TB-Profiler

Lineage	Family	RDs	Frequency
La1.2.BCG	M.bovis	None	0.06
lineage4.9	Euro-American (H37Rv-like)	None	0.94

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rrs	1472307	n.462C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance	Mutation from literature
embB	4247448	p.His312Arg	missense_variant	0.95	ethambutol		Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
dnaA	571	c.571T>C	synonymous_variant	0.91	isoniazid
dnaA	582	c.582A>C	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	588	c.588A>G	synonymous_variant	0.83	isoniazid
dnaA	591	c.591C>G	synonymous_variant	0.83	isoniazid
dnaA	597	c.597C>G	synonymous_variant	0.83	isoniazid	Not assoc w R - Interim
dnaA	600	c.600T>G	synonymous_variant	0.83	isoniazid
dnaA	609	c.609C>G	synonymous_variant	0.83	isoniazid
dnaA	610	c.610C>T	synonymous_variant	0.83	isoniazid
dnaA	645	c.645A>T	synonymous_variant	0.86	isoniazid
dnaA	708	c.708T>C	synonymous_variant	0.82	isoniazid
dnaA	711	c.711C>G	synonymous_variant	0.87	isoniazid
dnaA	741	c.741T>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	750	c.750C>T	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	756	c.756T>C	synonymous_variant	0.91	isoniazid
dnaA	771	c.771A>G	synonymous_variant	1.0	isoniazid
dnaA	777	c.777A>G	synonymous_variant	0.92	isoniazid
dnaA	786	c.786C>T	synonymous_variant	0.89	isoniazid
dnaA	792	c.792C>T	synonymous_variant	0.92	isoniazid
dnaA	795	c.795A>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	805	c.805T>C	synonymous_variant	1.0	isoniazid
dnaA	813	c.813C>T	synonymous_variant	0.88	isoniazid
dnaA	822	c.822A>G	synonymous_variant	0.89	isoniazid
dnaA	828	c.828T>C	synonymous_variant	0.89	isoniazid	Not assoc w R - Interim
dnaA	837	c.837A>G	synonymous_variant	0.87	isoniazid
dnaA	840	c.840G>A	synonymous_variant	0.87	isoniazid
dnaA	846	c.846T>C	synonymous_variant	0.87	isoniazid
dnaA	849	c.849A>G	synonymous_variant	0.87	isoniazid
dnaA	852	c.852G>A	synonymous_variant	0.82	isoniazid	Not assoc w R - Interim
dnaA	876	c.876C>G	synonymous_variant	0.88	isoniazid
dnaA	877	c.877T>C	synonymous_variant	0.88	isoniazid
dnaA	882	c.882C>T	synonymous_variant	0.88	isoniazid
dnaA	885	c.885T>C	synonymous_variant	0.88	isoniazid
dnaA	897	c.897A>G	synonymous_variant	0.82	isoniazid
dnaA	909	c.909A>C	synonymous_variant	0.79	isoniazid	Not assoc w R - Interim
dnaA	912	c.912T>G	synonymous_variant	0.79	isoniazid
dnaA	918	c.918C>G	synonymous_variant	0.92	isoniazid
dnaA	1220	p.Asn407Ser	missense_variant	0.87	isoniazid
dnaA	1230	c.1230A>G	synonymous_variant	0.83	isoniazid
dnaA	1236	c.1236C>T	synonymous_variant	0.86	isoniazid
dnaA	1242	c.1242G>C	synonymous_variant	0.86	isoniazid
dnaA	1245	c.1245G>C	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	1254	c.1254T>G	synonymous_variant	0.95	isoniazid
dnaA	1278	c.1278T>C	synonymous_variant	0.89	isoniazid
dnaA	1290	c.1290G>A	synonymous_variant	0.86	isoniazid
dnaA	1293	c.1293T>C	synonymous_variant	0.85	isoniazid
dnaA	1302	c.1302C>G	synonymous_variant	0.85	isoniazid
dnaA	1317	c.1317A>C	synonymous_variant	1.0	isoniazid
dnaA	1428	c.1428C>G	synonymous_variant	0.91	isoniazid
dnaA	1431	c.1431A>G	synonymous_variant	0.91	isoniazid
dnaA	1440	c.1440C>T	synonymous_variant	0.91	isoniazid
dnaA	1441	c.1441C>T	synonymous_variant	1.0	isoniazid
gyrB	6223	c.984G>C	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrB	6223	c.984G>C	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrB	6242	p.Arg335Lys	missense_variant	0.92	levofloxacin
gyrB	6242	p.Arg335Lys	missense_variant	0.92	moxifloxacin
gyrB	6250	c.1011A>G	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrB	6250	c.1011A>G	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrB	6262	c.1023G>A	synonymous_variant	0.94	levofloxacin
gyrB	6262	c.1023G>A	synonymous_variant	0.94	moxifloxacin
gyrB	6268	c.1029C>G	synonymous_variant	0.94	levofloxacin
gyrB	6268	c.1029C>G	synonymous_variant	0.94	moxifloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.94	levofloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.94	moxifloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.95	levofloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.95	moxifloxacin
gyrB	6292	c.1053G>T	synonymous_variant	0.94	levofloxacin
gyrB	6292	c.1053G>T	synonymous_variant	0.94	moxifloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.84	levofloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.84	moxifloxacin
gyrB	6307	c.1068T>G	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrB	6307	c.1068T>G	synonymous_variant	0.89	moxifloxacin	Not assoc w R - Interim
gyrB	6319	c.1080G>C	synonymous_variant	0.82	levofloxacin	Not assoc w R - Interim
gyrB	6319	c.1080G>C	synonymous_variant	0.82	moxifloxacin
gyrA	6355	c.-947G>A	upstream_gene_variant	0.94	levofloxacin
gyrA	6355	c.-947G>A	upstream_gene_variant	0.94	moxifloxacin
gyrA	6362	c.-940T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6362	c.-940T>C	upstream_gene_variant	0.94	moxifloxacin
gyrA	6376	c.-926G>A	upstream_gene_variant	0.93	levofloxacin
gyrA	6376	c.-926G>A	upstream_gene_variant	0.93	moxifloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	0.94	moxifloxacin
gyrB	6391	c.1152G>C	synonymous_variant	0.82	levofloxacin	Not assoc w R - Interim
gyrB	6391	c.1152G>C	synonymous_variant	0.82	moxifloxacin	Not assoc w R - Interim
gyrB	6397	c.1158G>A	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrB	6397	c.1158G>A	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	6403	c.-899T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	0.94	moxifloxacin
gyrA	6412	c.-890G>A	upstream_gene_variant	0.92	levofloxacin
gyrA	6412	c.-890G>A	upstream_gene_variant	0.92	moxifloxacin
gyrA	6415	c.-887G>C	upstream_gene_variant	0.91	levofloxacin
gyrA	6415	c.-887G>C	upstream_gene_variant	0.91	moxifloxacin
gyrA	6418	c.-884C>G	upstream_gene_variant	0.91	levofloxacin
gyrA	6418	c.-884C>G	upstream_gene_variant	0.91	moxifloxacin
gyrA	6427	c.-875T>C	upstream_gene_variant	0.91	levofloxacin
gyrA	6427	c.-875T>C	upstream_gene_variant	0.91	moxifloxacin
gyrA	6610	c.-692C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6610	c.-692C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.73	levofloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.73	moxifloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.8	levofloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.8	moxifloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	0.91	levofloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	0.91	moxifloxacin
gyrB	6793	c.1554T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrB	6798	p.Gly520Ala	missense_variant	0.92	levofloxacin	Not assoc w R
gyrB	6798	p.Gly520Ala	missense_variant	0.92	moxifloxacin	Uncertain significance
gyrA	6803	c.-499C>T	upstream_gene_variant	0.73	levofloxacin
gyrA	6803	c.-499C>T	upstream_gene_variant	0.73	moxifloxacin
gyrA	7141	c.-161T>C	upstream_gene_variant	0.8	levofloxacin
gyrA	7141	c.-161T>C	upstream_gene_variant	0.8	moxifloxacin
gyrA	7147	c.-155G>C	upstream_gene_variant	0.91	levofloxacin
gyrA	7147	c.-155G>C	upstream_gene_variant	0.91	moxifloxacin
gyrA	7150	c.-152G>C	upstream_gene_variant	0.92	levofloxacin
gyrA	7150	c.-152G>C	upstream_gene_variant	0.92	moxifloxacin
gyrB	7162	c.1923C>T	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrB	7162	c.1923C>T	synonymous_variant	0.89	moxifloxacin	Not assoc w R - Interim
gyrA	7178	c.-124T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	7178	c.-124T>C	upstream_gene_variant	0.94	moxifloxacin
gyrA	7210	c.-92C>T	upstream_gene_variant	0.91	levofloxacin
gyrA	7210	c.-92C>T	upstream_gene_variant	0.91	moxifloxacin
gyrB	7216	c.1977G>C	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrB	7216	c.1977G>C	synonymous_variant	0.91	moxifloxacin
gyrA	7361	c.60C>T	synonymous_variant	0.8	levofloxacin
gyrA	7361	c.60C>T	synonymous_variant	0.8	moxifloxacin
gyrA	7362	p.Glu21Gln	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7362	p.Glu21Gln	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7406	c.105G>C	synonymous_variant	0.95	levofloxacin
gyrA	7406	c.105G>C	synonymous_variant	0.95	moxifloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.87	levofloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.87	moxifloxacin
gyrA	7433	c.132G>T	synonymous_variant	0.83	levofloxacin
gyrA	7433	c.132G>T	synonymous_variant	0.83	moxifloxacin
gyrA	7442	c.141G>T	synonymous_variant	1.0	levofloxacin
gyrA	7442	c.141G>T	synonymous_variant	1.0	moxifloxacin
gyrA	7445	c.144C>T	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	7445	c.144C>T	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	7451	c.150C>G	synonymous_variant	1.0	levofloxacin
gyrA	7451	c.150C>G	synonymous_variant	1.0	moxifloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.85	levofloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.85	moxifloxacin
gyrA	7475	c.174A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7475	c.174A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7480	p.Phe60Tyr	missense_variant	0.88	levofloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.88	moxifloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.96	levofloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.96	moxifloxacin
gyrA	7508	c.207C>T	synonymous_variant	0.83	levofloxacin
gyrA	7508	c.207C>T	synonymous_variant	0.83	moxifloxacin
gyrA	7523	c.222C>G	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	7523	c.222C>G	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	7532	c.231T>G	synonymous_variant	0.84	levofloxacin	Not assoc w R - Interim
gyrA	7532	c.231T>G	synonymous_variant	0.84	moxifloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	7547	c.246C>T	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrA	7547	c.246C>T	synonymous_variant	0.89	moxifloxacin	Not assoc w R - Interim
gyrA	7571	c.270G>C	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	7571	c.270G>C	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	7577	c.276C>T	synonymous_variant	0.83	levofloxacin
gyrA	7577	c.276C>T	synonymous_variant	0.83	moxifloxacin
gyrA	7585	p.Ser95Thr	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7587	c.286C>T	synonymous_variant	0.82	levofloxacin	Not assoc w R - Interim
gyrA	7587	c.286C>T	synonymous_variant	0.82	moxifloxacin	Not assoc w R - Interim
gyrA	7592	c.291G>C	synonymous_variant	0.86	levofloxacin	Not assoc w R - Interim
gyrA	7592	c.291G>C	synonymous_variant	0.86	moxifloxacin	Not assoc w R - Interim
gyrA	7595	c.294C>G	synonymous_variant	0.95	levofloxacin
gyrA	7595	c.294C>G	synonymous_variant	0.95	moxifloxacin
gyrA	7607	c.306C>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	7607	c.306C>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	7763	c.462T>C	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	7763	c.462T>C	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	7769	c.468C>T	synonymous_variant	0.93	levofloxacin
gyrA	7769	c.468C>T	synonymous_variant	0.93	moxifloxacin
gyrA	7778	c.477G>C	synonymous_variant	0.93	levofloxacin
gyrA	7778	c.477G>C	synonymous_variant	0.93	moxifloxacin
gyrA	7784	c.483A>G	synonymous_variant	0.93	levofloxacin
gyrA	7784	c.483A>G	synonymous_variant	0.93	moxifloxacin
gyrA	7793	c.492G>C	synonymous_variant	0.93	levofloxacin
gyrA	7793	c.492G>C	synonymous_variant	0.93	moxifloxacin
gyrA	7796	c.495G>A	synonymous_variant	0.93	levofloxacin
gyrA	7796	c.495G>A	synonymous_variant	0.93	moxifloxacin
gyrA	7799	c.498A>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	7799	c.498A>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	7832	c.531G>C	synonymous_variant	1.0	levofloxacin
gyrA	7832	c.531G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7835	c.534A>C	synonymous_variant	1.0	levofloxacin
gyrA	7835	c.534A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8099	c.798T>C	synonymous_variant	1.0	levofloxacin
gyrA	8099	c.798T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8121	c.820T>C	synonymous_variant	0.94	levofloxacin
gyrA	8121	c.820T>C	synonymous_variant	0.94	moxifloxacin
gyrA	8135	c.834C>G	synonymous_variant	0.95	levofloxacin
gyrA	8135	c.834C>G	synonymous_variant	0.95	moxifloxacin
gyrA	8156	c.855T>C	synonymous_variant	1.0	levofloxacin
gyrA	8156	c.855T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8168	c.867A>G	synonymous_variant	1.0	levofloxacin
gyrA	8168	c.867A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8174	c.873C>T	synonymous_variant	0.96	levofloxacin
gyrA	8174	c.873C>T	synonymous_variant	0.96	moxifloxacin
gyrA	8177	c.876A>C	synonymous_variant	1.0	levofloxacin
gyrA	8177	c.876A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8198	c.897T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8198	c.897T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8207	c.906T>C	synonymous_variant	0.95	levofloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.95	moxifloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.95	levofloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.95	moxifloxacin
gyrA	8219	c.918T>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8219	c.918T>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8228	c.927G>C	synonymous_variant	0.94	levofloxacin
gyrA	8228	c.927G>C	synonymous_variant	0.94	moxifloxacin
gyrA	8237	c.936A>G	synonymous_variant	0.95	levofloxacin
gyrA	8237	c.936A>G	synonymous_variant	0.95	moxifloxacin
gyrA	8246	c.945C>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8246	c.945C>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8247	p.Ile316Val	missense_variant	0.94	levofloxacin
gyrA	8247	p.Ile316Val	missense_variant	0.94	moxifloxacin
gyrA	8264	c.963T>C	synonymous_variant	0.93	levofloxacin
gyrA	8264	c.963T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8267	c.966G>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8267	c.966G>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8283	p.Ile328Leu	missense_variant	0.92	levofloxacin	Uncertain significance
gyrA	8283	p.Ile328Leu	missense_variant	0.92	moxifloxacin	Uncertain significance
gyrA	8288	c.987T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8288	c.987T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8324	c.1023T>C	synonymous_variant	1.0	levofloxacin
gyrA	8324	c.1023T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8337	c.1036_1038delCTAinsTTG	synonymous_variant	1.0	levofloxacin
gyrA	8337	c.1036_1038delCTAinsTTG	synonymous_variant	1.0	moxifloxacin
gyrA	8340	p.Ala347Ser	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	8340	p.Ala347Ser	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	8360	c.1059G>A	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	8360	c.1059G>A	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	8369	c.1068G>A	synonymous_variant	0.93	levofloxacin
gyrA	8369	c.1068G>A	synonymous_variant	0.93	moxifloxacin
gyrA	8372	c.1071G>A	synonymous_variant	0.92	levofloxacin
gyrA	8372	c.1071G>A	synonymous_variant	0.92	moxifloxacin
gyrA	8375	c.1074G>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8375	c.1074G>C	synonymous_variant	0.92	moxifloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.92	levofloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.92	moxifloxacin
gyrA	8393	c.1092T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8393	c.1092T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8399	c.1098T>C	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrA	8399	c.1098T>C	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrA	8405	c.1104C>T	synonymous_variant	0.9	levofloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.9	moxifloxacin
gyrA	8420	c.1119T>C	synonymous_variant	1.0	levofloxacin
gyrA	8420	c.1119T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8423	c.1122G>C	synonymous_variant	0.83	levofloxacin
gyrA	8423	c.1122G>C	synonymous_variant	0.83	moxifloxacin
gyrA	8585	c.1284C>T	synonymous_variant	1.0	levofloxacin
gyrA	8585	c.1284C>T	synonymous_variant	1.0	moxifloxacin
gyrA	8603	c.1302A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8603	c.1302A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>C	synonymous_variant	0.94	levofloxacin
gyrA	8624	c.1323G>C	synonymous_variant	0.94	moxifloxacin
gyrA	8627	c.1326C>G	synonymous_variant	1.0	levofloxacin
gyrA	8627	c.1326C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8636	c.1335A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8636	c.1335A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8655	p.Ile452Val	missense_variant	0.95	levofloxacin
gyrA	8655	p.Ile452Val	missense_variant	0.95	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8693	c.1392T>C	synonymous_variant	1.0	levofloxacin
gyrA	8693	c.1392T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8711	c.1410A>C	synonymous_variant	1.0	levofloxacin
gyrA	8711	c.1410A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8714	c.1413A>G	synonymous_variant	1.0	levofloxacin
gyrA	8714	c.1413A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8729	c.1428T>C	synonymous_variant	1.0	levofloxacin
gyrA	8729	c.1428T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8730	p.Gly477Arg	missense_variant	0.92	levofloxacin	Uncertain significance
gyrA	8730	p.Gly477Arg	missense_variant	0.92	moxifloxacin
gyrA	8740	p.Arg480His	missense_variant	0.92	levofloxacin
gyrA	8740	p.Arg480His	missense_variant	0.92	moxifloxacin
gyrA	8747	c.1446A>G	synonymous_variant	0.82	levofloxacin
gyrA	8747	c.1446A>G	synonymous_variant	0.82	moxifloxacin
gyrA	8897	c.1596T>C	synonymous_variant	0.67	levofloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	0.67	moxifloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8915	c.1614A>G	synonymous_variant	0.77	levofloxacin	Not assoc w R - Interim
gyrA	8915	c.1614A>G	synonymous_variant	0.77	moxifloxacin	Not assoc w R - Interim
gyrA	8939	c.1638T>C	synonymous_variant	1.0	levofloxacin
gyrA	8939	c.1638T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.75	levofloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.75	moxifloxacin
gyrA	8945	c.1644G>C	synonymous_variant	1.0	levofloxacin
gyrA	8945	c.1644G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8946	c.1645_1647delTTGinsCTC	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8946	c.1645_1647delTTGinsCTC	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8963	c.1662C>A	synonymous_variant	0.67	levofloxacin
gyrA	8963	c.1662C>A	synonymous_variant	0.67	moxifloxacin
gyrA	8966	c.1665C>G	synonymous_variant	0.67	levofloxacin	Not assoc w R - Interim
gyrA	8966	c.1665C>G	synonymous_variant	0.67	moxifloxacin	Not assoc w R - Interim
gyrA	8967	p.Ala556Arg	missense_variant	0.67	levofloxacin
gyrA	8967	p.Ala556Arg	missense_variant	0.67	moxifloxacin
gyrA	8983	p.Cys561Ser	missense_variant	0.67	levofloxacin
gyrA	8983	p.Cys561Ser	missense_variant	0.67	moxifloxacin
gyrA	9304	p.Gly668Asp	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	9304	p.Gly668Asp	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	9308	p.Asp669Glu	missense_variant	0.82	levofloxacin
gyrA	9308	p.Asp669Glu	missense_variant	0.82	moxifloxacin
gyrA	9315	c.2014C>T	synonymous_variant	0.75	levofloxacin	Not assoc w R - Interim
gyrA	9315	c.2014C>T	synonymous_variant	0.75	moxifloxacin	Not assoc w R - Interim
gyrA	9318	c.2017C>T	synonymous_variant	0.77	levofloxacin	Not assoc w R - Interim
gyrA	9318	c.2017C>T	synonymous_variant	0.77	moxifloxacin
gyrA	9329	c.2028C>G	synonymous_variant	0.83	levofloxacin
gyrA	9329	c.2028C>G	synonymous_variant	0.83	moxifloxacin
gyrA	9335	c.2034G>C	synonymous_variant	0.92	levofloxacin
gyrA	9335	c.2034G>C	synonymous_variant	0.92	moxifloxacin
mshA	574683	c.-665T>C	upstream_gene_variant	0.91	isoniazid	Uncertain significance
mshA	574683	c.-665T>C	upstream_gene_variant	0.91	ethionamide
mshA	574688	c.-660G>C	upstream_gene_variant	1.0	isoniazid	Uncertain significance
mshA	574688	c.-660G>C	upstream_gene_variant	1.0	ethionamide	Uncertain significance
mshA	574694	c.-654C>G	upstream_gene_variant	0.91	isoniazid
mshA	574694	c.-654C>G	upstream_gene_variant	0.91	ethionamide
mshA	575737	c.390T>C	synonymous_variant	1.0	isoniazid
mshA	575737	c.390T>C	synonymous_variant	1.0	ethionamide
mshA	575746	c.399C>G	synonymous_variant	0.64	isoniazid
mshA	575746	c.399C>G	synonymous_variant	0.64	ethionamide
ccsA	619570	c.-321G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619574	c.-317G>A	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619579	c.-312G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619591	c.-300G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619618	c.-273C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619627	c.-264C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619634	c.-257T>A	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619645	c.-246G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619654	c.-237A>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620198	p.Gln103Leu	missense_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620362	p.Ala158Thr	missense_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620373	c.483C>G	synonymous_variant	0.9	kanamycin
					capreomycin
					amikacin
ccsA	620385	c.495G>T	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620412	c.522T>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620433	c.543C>G	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
ccsA	620436	c.546T>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620439	c.549T>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620445	c.555A>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620454	c.564C>T	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620763	c.873G>A	synonymous_variant	0.7	kanamycin
					capreomycin
					amikacin
ccsA	620809	c.919C>T	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620823	c.933C>T	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620829	c.939G>C	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
Rv0565c	656457	c.1014T>C	synonymous_variant	0.91	ethionamide
Rv0565c	656481	c.990A>G	synonymous_variant	1.0	ethionamide
Rv0565c	656484	c.987T>C	synonymous_variant	1.0	ethionamide
Rv0565c	656487	c.984T>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
Rv0565c	656493	c.978C>G	synonymous_variant	1.0	ethionamide
Rv0565c	656502	p.His323Lys	missense_variant	0.94	ethionamide
Rv0565c	656511	p.His320Gln	missense_variant	1.0	ethionamide
Rv0565c	656533	c.937_938delCGinsAGA	frameshift_variant&missense_variant	0.83	ethionamide	Uncertain significance
Rv0565c	656535	c.936C>G	synonymous_variant	0.83	ethionamide
Rv0565c	656539	c.931delA	frameshift_variant	1.0	ethionamide	Uncertain significance
Rv0565c	657632	c.-162G>A	upstream_gene_variant	0.9	ethionamide
Rv0565c	657649	c.-179G>A	upstream_gene_variant	0.94	ethionamide
Rv0565c	657650	c.-180G>A	upstream_gene_variant	0.94	ethionamide
Rv0565c	657671	c.-201A>G	upstream_gene_variant	0.82	ethionamide
Rv0565c	657678	c.-208A>C	upstream_gene_variant	0.86	ethionamide
Rv0565c	657680	c.-210G>A	upstream_gene_variant	0.86	ethionamide
Rv0565c	657686	c.-216C>G	upstream_gene_variant	0.86	ethionamide
Rv0565c	657689	c.-220_-219delCAinsAC	upstream_gene_variant	1.0	ethionamide
Rv0565c	657701	c.-231C>G	upstream_gene_variant	0.86	ethionamide
Rv0565c	657734	c.-264T>C	upstream_gene_variant	1.0	ethionamide
hadA	731768	c.-162G>A	upstream_gene_variant	0.9	isoniazid
hadA	731774	c.-156T>C	upstream_gene_variant	0.9	isoniazid
hadA	731789	c.-141A>G	upstream_gene_variant	0.91	isoniazid
hadA	731792	c.-138G>A	upstream_gene_variant	0.91	isoniazid
hadA	731801	c.-129C>G	upstream_gene_variant	0.9	isoniazid
hadA	732270	p.Glu114Val	missense_variant	0.91	isoniazid
hadA	732272	p.Ala115Ser	missense_variant	0.91	isoniazid
hadA	732301	c.372G>A	synonymous_variant	0.93	isoniazid
hadA	732305	p.Ile126Val	missense_variant	0.93	isoniazid
hadA	732308	p.Val127Ile	missense_variant	0.93	isoniazid
hadA	732319	c.390G>A	synonymous_variant	0.93	isoniazid
hadA	732321	p.Glu131Ala	missense_variant	0.92	isoniazid
hadA	732329	p.Leu134Val	missense_variant	0.88	isoniazid	Uncertain significance
hadA	732346	c.417T>C	synonymous_variant	0.94	isoniazid
hadA	732370	c.441C>T	synonymous_variant	0.92	isoniazid
hadA	732378	c.450_452dupAGA	disruptive_inframe_insertion	0.93	isoniazid
hadA	732389	p.Ser154Thr	missense_variant	0.88	isoniazid
hadA	732396	p.Gly156Ala	missense_variant	0.94	isoniazid
hadA	732398	p.Ala157Thr	missense_variant	0.94	isoniazid
nusG	734093	c.-161A>C	upstream_gene_variant	1.0	rifampicin
nusG	734102	c.-152G>C	upstream_gene_variant	1.0	rifampicin
nusG	734111	c.-143A>G	upstream_gene_variant	1.0	rifampicin
nusG	734129	c.-125G>C	upstream_gene_variant	0.91	rifampicin
nusG	734132	c.-122G>C	upstream_gene_variant	0.91	rifampicin
nusG	734135	c.-119G>T	upstream_gene_variant	1.0	rifampicin
nusG	734144	c.-110G>T	upstream_gene_variant	1.0	rifampicin
nusG	734403	c.150C>T	synonymous_variant	0.92	rifampicin
nusG	734407	p.Val52Ile	missense_variant	1.0	rifampicin
nusG	734421	c.168A>G	synonymous_variant	1.0	rifampicin
nusG	734424	c.171G>A	synonymous_variant	1.0	rifampicin
nusG	734442	c.189G>A	synonymous_variant	1.0	rifampicin
nusG	734451	c.198G>C	synonymous_variant	1.0	rifampicin
nusG	734457	c.204C>G	synonymous_variant	0.89	rifampicin
nusG	734460	c.207G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734472	c.219T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734475	c.222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734502	c.249G>A	synonymous_variant	0.88	rifampicin
nusG	734520	c.267C>G	synonymous_variant	0.85	rifampicin
nusG	734532	c.279A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734541	c.288A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734559	c.306T>C	synonymous_variant	1.0	rifampicin
nusG	734580	c.327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734589	c.336G>C	synonymous_variant	1.0	rifampicin
nusG	734595	c.342C>T	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
nusG	734596	c.343T>C	synonymous_variant	1.0	rifampicin
nusG	734610	c.357C>G	synonymous_variant	0.92	rifampicin
nusG	734826	c.573A>G	synonymous_variant	1.0	rifampicin
nusG	734829	c.576C>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
nusG	734832	c.579C>G	synonymous_variant	0.91	rifampicin
nusG	734850	c.597C>G	synonymous_variant	0.86	rifampicin
nusG	734853	c.600A>G	synonymous_variant	0.86	rifampicin
nusG	734854	c.601T>C	synonymous_variant	0.93	rifampicin
nusG	734865	c.612G>C	synonymous_variant	0.87	rifampicin
nusG	734882	p.Ala210Gly	missense_variant	0.94	rifampicin
nusG	734895	c.642A>G	synonymous_variant	0.91	rifampicin
rpoB	760101	c.295T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760112	c.306T>C	synonymous_variant	0.93	rifampicin
rpoB	760118	c.312T>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	760130	p.Asp108Glu	missense_variant	0.93	rifampicin	Uncertain significance
rpoB	760139	c.333A>G	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	760142	c.336C>G	synonymous_variant	0.87	rifampicin
rpoB	760181	c.375T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760184	c.378A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760196	c.390C>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	760223	c.417T>C	synonymous_variant	0.75	rifampicin
rpoB	760235	c.429T>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	760307	c.501T>C	synonymous_variant	0.9	rifampicin
rpoB	760328	c.522G>C	synonymous_variant	0.86	rifampicin
rpoB	760331	c.525G>C	synonymous_variant	1.0	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	760357	p.Thr184Ser	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	760361	c.555T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760370	c.564C>G	synonymous_variant	0.93	rifampicin
rpoB	760376	p.Asp190Glu	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	760380	p.Thr192Leu	missense_variant	0.78	rifampicin
rpoB	760403	c.597C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoB	760412	c.606C>G	synonymous_variant	0.74	rifampicin
rpoB	760415	c.609C>T	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	760418	c.612G>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	760424	c.618C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760451	c.645C>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoB	760463	c.657C>G	synonymous_variant	0.95	rifampicin
rpoB	760475	c.669A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760478	c.672C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760484	c.678A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760522	p.Ser239Asn	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	760532	c.726T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Thr	missense_variant	1.0	rifampicin
rpoB	760547	c.741G>T	synonymous_variant	0.96	rifampicin
rpoB	760563	p.Arg253Met	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760589	c.783C>G	synonymous_variant	0.89	rifampicin
rpoB	760591	p.Val262Ala	missense_variant	1.0	rifampicin
rpoB	760611	c.805T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760643	c.837G>A	synonymous_variant	0.83	rifampicin
rpoB	760646	c.840C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760655	c.849A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760661	c.855A>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>C	synonymous_variant	0.9	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760724	c.918T>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	760730	c.924T>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	760769	c.963C>G	synonymous_variant	0.91	rifampicin
rpoB	760784	c.978G>C	synonymous_variant	0.91	rifampicin
rpoB	760793	c.987A>G	synonymous_variant	0.92	rifampicin
rpoB	760805	c.999G>C	synonymous_variant	0.92	rifampicin
rpoB	760820	c.1014T>C	synonymous_variant	1.0	rifampicin
rpoB	760859	c.1053T>C	synonymous_variant	1.0	rifampicin
rpoB	760862	c.1056G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760877	c.1071G>T	synonymous_variant	1.0	rifampicin
rpoB	760886	c.1080A>G	synonymous_variant	1.0	rifampicin
rpoB	760919	c.1113C>G	synonymous_variant	1.0	rifampicin
rpoB	760925	c.1119T>C	synonymous_variant	1.0	rifampicin
rpoB	760928	c.1122G>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760931	c.1125C>G	synonymous_variant	0.95	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760964	c.1158C>T	synonymous_variant	0.88	rifampicin
rpoB	760970	c.1164G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760982	c.1176G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761015	c.1209G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761021	c.1215G>C	synonymous_variant	0.84	rifampicin
rpoB	761027	c.1221A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761036	c.1230G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761057	c.1251G>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	761097	c.1291_1293delAGCinsTCG	synonymous_variant	1.0	rifampicin
rpoB	761102	c.1296A>G	synonymous_variant	1.0	rifampicin
rpoB	761132	c.1326G>T	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	761133	c.1327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761147	c.1341C>T	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761165	c.1359G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761180	c.1374A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761189	c.1383T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761195	c.1389G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761198	c.1392G>A	synonymous_variant	0.89	rifampicin
rpoB	761207	c.1401C>G	synonymous_variant	0.87	rifampicin
rpoB	761249	c.1443A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761255	c.1449T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761258	c.1452G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761261	c.1455G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761286	c.1480C>T	synonymous_variant	1.0	rifampicin
rpoB	761297	c.1491C>T	synonymous_variant	1.0	rifampicin
rpoB	761327	c.1521A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761333	c.1527G>A	synonymous_variant	0.93	rifampicin
rpoB	761345	c.1539G>T	synonymous_variant	0.93	rifampicin
rpoB	761354	c.1548C>T	synonymous_variant	1.0	rifampicin
rpoB	761358	p.Val518Ile	missense_variant	0.92	rifampicin
rpoB	761373	p.Val523His	missense_variant	0.9	rifampicin
rpoB	761492	c.1686G>C	synonymous_variant	1.0	rifampicin
rpoB	761510	c.1704T>C	synonymous_variant	1.0	rifampicin
rpoB	761531	c.1725C>G	synonymous_variant	0.89	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761600	c.1794T>G	synonymous_variant	0.93	rifampicin
rpoB	761606	c.1800C>G	synonymous_variant	0.94	rifampicin
rpoB	761612	c.1806G>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761954	c.2148C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761969	c.2163G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762014	c.2208C>T	synonymous_variant	1.0	rifampicin
rpoB	762053	c.2247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762062	c.2256T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762095	c.2289C>T	synonymous_variant	0.92	rifampicin
rpoB	762101	c.2295C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	762138	c.2332C>T	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762143	c.2337T>C	synonymous_variant	1.0	rifampicin
rpoB	762149	c.2343G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762161	c.2355C>G	synonymous_variant	0.94	rifampicin
rpoB	762185	c.2379G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762209	c.2403C>T	synonymous_variant	0.83	rifampicin
rpoB	762233	c.2427G>T	synonymous_variant	1.0	rifampicin
rpoB	762254	c.2448T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762284	c.2478G>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762296	c.2490G>A	synonymous_variant	0.85	rifampicin
rpoB	762317	c.2511A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	762329	c.2523G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	762338	c.2532T>C	synonymous_variant	0.89	rifampicin
rpoB	762347	c.2541T>C	synonymous_variant	0.94	rifampicin
rpoB	762362	p.Glu852Asp	missense_variant	0.95	rifampicin
rpoB	762369	c.2563T>C	synonymous_variant	0.95	rifampicin
rpoC	762389	c.-981G>A	upstream_gene_variant	0.95	rifampicin
rpoC	762398	c.-972T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762401	c.-969G>C	upstream_gene_variant	1.0	rifampicin
rpoB	762404	c.2598T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762410	c.-960T>C	upstream_gene_variant	1.0	rifampicin
rpoB	762416	c.2610A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762419	c.-951C>G	upstream_gene_variant	1.0	rifampicin
rpoB	762449	c.2643C>A	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	762452	c.2646G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	762509	c.-861T>G	upstream_gene_variant	0.92	rifampicin
rpoB	762510	p.Ala902Pro	missense_variant	0.92	rifampicin	Uncertain significance
rpoC	762521	c.-849C>G	upstream_gene_variant	0.73	rifampicin
rpoC	762527	c.-843G>C	upstream_gene_variant	0.73	rifampicin
rpoC	762533	c.-837T>C	upstream_gene_variant	0.91	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	0.91	rifampicin
rpoC	762537	c.-833T>C	upstream_gene_variant	0.73	rifampicin
rpoC	762758	c.-612G>C	upstream_gene_variant	0.9	rifampicin
rpoC	762776	c.-594C>T	upstream_gene_variant	0.92	rifampicin
rpoB	762785	p.Asp993Glu	missense_variant	0.92	rifampicin	Uncertain significance
rpoB	762788	c.2982G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	762789	p.Leu995Met	missense_variant	0.85	rifampicin	Uncertain significance
rpoB	762799	p.Ala998Gly	missense_variant	0.87	rifampicin	Uncertain significance
rpoB	762812	c.3006C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	762813	p.Met1003Val	missense_variant	0.93	rifampicin
rpoC	762818	c.-552C>A	upstream_gene_variant	0.87	rifampicin
rpoB	762827	c.3021G>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	762836	c.3030C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762857	c.3051C>G	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	762860	c.3054G>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	762929	c.3123G>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	762962	c.3156C>T	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoC	762983	c.-387C>T	upstream_gene_variant	1.0	rifampicin
rpoC	762989	c.-381G>C	upstream_gene_variant	0.77	rifampicin
rpoB	763034	c.3228C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	763040	c.3234C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	763070	c.3264T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	763085	c.3279C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	763115	c.3309T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	763136	c.3330C>T	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	763139	c.-231C>T	upstream_gene_variant	0.82	rifampicin
rpoC	763148	c.-222G>C	upstream_gene_variant	0.84	rifampicin
rpoC	763158	c.-212C>T	upstream_gene_variant	0.95	rifampicin
rpoB	763166	c.3360A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763169	c.-201A>G	upstream_gene_variant	0.96	rifampicin
rpoC	763178	c.-192G>C	upstream_gene_variant	0.88	rifampicin
rpoC	763181	c.-189G>C	upstream_gene_variant	0.88	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	0.95	rifampicin
rpoC	763205	c.-165G>C	upstream_gene_variant	0.89	rifampicin
rpoC	763208	c.-162T>C	upstream_gene_variant	0.95	rifampicin
rpoC	763226	c.-144A>G	upstream_gene_variant	0.94	rifampicin
rpoB	763238	c.3432T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	763441	c.72C>T	synonymous_variant	1.0	rifampicin
rpoC	763444	c.75T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763456	c.87A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763486	c.117T>G	synonymous_variant	1.0	rifampicin
rpoC	763495	c.126G>A	synonymous_variant	0.96	rifampicin
rpoC	763528	c.159G>A	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>T	synonymous_variant	0.83	rifampicin
rpoC	763573	c.204G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	763576	c.207C>G	synonymous_variant	0.75	rifampicin
rpoC	763594	c.225C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763603	c.234C>T	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoC	763615	c.246G>A	synonymous_variant	0.83	rifampicin
rpoC	763636	c.267T>C	synonymous_variant	1.0	rifampicin
rpoC	763657	c.288G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763660	c.291T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763669	c.300C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763675	c.306C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763696	c.327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763711	c.342G>C	synonymous_variant	0.93	rifampicin
rpoC	763723	c.354G>C	synonymous_variant	1.0	rifampicin
rpoC	763732	c.363C>G	synonymous_variant	1.0	rifampicin
rpoC	763741	c.372C>T	synonymous_variant	0.95	rifampicin
rpoC	763744	c.375G>C	synonymous_variant	1.0	rifampicin
rpoC	763765	c.396T>C	synonymous_variant	1.0	rifampicin
rpoC	763807	c.438T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763831	c.462A>G	synonymous_variant	0.85	rifampicin
rpoC	763835	p.Ala156Met	missense_variant	0.82	rifampicin
rpoC	763853	p.Val162Ile	missense_variant	0.9	rifampicin
rpoC	763858	c.489A>G	synonymous_variant	1.0	rifampicin
rpoC	763872	p.Gly168Ala	missense_variant	1.0	rifampicin
rpoC	763876	p.Glu169Asp	missense_variant	1.0	rifampicin
rpoC	763879	c.510A>G	synonymous_variant	1.0	rifampicin
rpoC	763888	c.519G>C	synonymous_variant	1.0	rifampicin
rpoC	763891	c.522G>C	synonymous_variant	0.86	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	1.0	rifampicin
rpoC	763933	c.564C>T	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoC	763945	c.576T>C	synonymous_variant	0.8	rifampicin
rpoC	763951	c.582G>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	763960	c.591T>C	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoC	763969	c.600C>T	synonymous_variant	0.69	rifampicin	Not assoc w R - Interim
rpoC	763972	c.603C>T	synonymous_variant	0.69	rifampicin
rpoC	763991	p.Ile208Leu	missense_variant	0.64	rifampicin
rpoC	763996	c.627T>C	synonymous_variant	0.92	rifampicin
rpoC	764005	c.636G>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	764011	c.642T>C	synonymous_variant	0.75	rifampicin
rpoC	764083	c.714A>G	synonymous_variant	1.0	rifampicin
rpoC	764098	c.729A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764101	c.732C>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	764102	p.Val245Ile	missense_variant	0.91	rifampicin
rpoC	764110	c.741C>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764131	c.762T>C	synonymous_variant	1.0	rifampicin
rpoC	764159	c.790C>T	synonymous_variant	0.88	rifampicin
rpoC	764206	c.837T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764242	c.873C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764257	c.888G>C	synonymous_variant	0.92	rifampicin
rpoC	764269	c.900G>C	synonymous_variant	0.93	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	1.0	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764293	c.924G>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764320	c.951C>T	synonymous_variant	0.81	rifampicin
rpoC	764338	c.969G>A	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764365	c.996C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764383	c.1014C>G	synonymous_variant	0.92	rifampicin
rpoC	764405	c.1036A>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764419	c.1050C>G	synonymous_variant	0.73	rifampicin
rpoC	764428	c.1059G>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoC	764431	c.1062G>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	764434	c.1065A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764446	c.1077T>C	synonymous_variant	0.91	rifampicin
rpoC	764449	c.1080G>C	synonymous_variant	0.91	rifampicin
rpoC	764452	c.1083T>C	synonymous_variant	0.9	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764489	c.1120C>T	synonymous_variant	0.76	rifampicin
rpoC	764497	c.1128A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	764500	c.1131C>G	synonymous_variant	0.81	rifampicin
rpoC	764521	c.1152T>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>C	synonymous_variant	0.88	rifampicin
rpoC	764539	c.1170C>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764554	c.1185C>T	synonymous_variant	0.89	rifampicin
rpoC	764560	c.1191T>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	764566	c.1197C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	764575	c.1206T>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764576	c.1207_1208delTCinsAG	synonymous_variant	0.92	rifampicin
rpoC	764593	c.1224C>A	synonymous_variant	1.0	rifampicin
rpoC	764626	c.1257C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764668	c.1299C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764692	c.1323C>T	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	764746	c.1377G>A	synonymous_variant	0.91	rifampicin
rpoC	764752	c.1383G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764764	c.1395T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764803	c.1434C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764809	c.1440C>T	synonymous_variant	1.0	rifampicin	Not assoc w R
rpoC	764815	c.1446A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764827	c.1458G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764858	c.1489T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764872	c.1503A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764932	c.1563C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764948	c.1579T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	764959	c.1590G>A	synonymous_variant	0.93	rifampicin
rpoC	764968	c.1599T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764971	c.1602C>T	synonymous_variant	1.0	rifampicin
rpoC	765352	c.1983G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	765370	c.2001G>A	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	765371	c.2002C>T	synonymous_variant	0.86	rifampicin
rpoC	765383	p.Met672Leu	missense_variant	0.88	rifampicin	Uncertain significance
rpoC	765404	p.Leu679Val	missense_variant	0.93	rifampicin
rpoC	765409	c.2040T>C	synonymous_variant	1.0	rifampicin
rpoC	765421	c.2052C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765451	c.2082C>T	synonymous_variant	0.8	rifampicin
rpoC	765452	p.Ala695Ser	missense_variant	0.9	rifampicin
rpoC	765478	c.2109T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765508	c.2139C>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	765580	c.2211G>C	synonymous_variant	0.9	rifampicin
rpoC	765613	p.His748Gln	missense_variant	0.92	rifampicin
rpoC	765625	c.2256C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765628	c.2259G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765631	p.Asp754Glu	missense_variant	0.93	rifampicin
rpoC	765658	c.2289C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765700	c.2331T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765751	c.2382C>G	synonymous_variant	0.87	rifampicin
rpoC	765753	p.Asp795Ala	missense_variant	0.93	rifampicin	Uncertain significance
rpoC	765772	c.2403C>G	synonymous_variant	0.9	rifampicin
rpoC	765784	c.2415C>G	synonymous_variant	0.95	rifampicin
rpoC	765793	c.2424C>G	synonymous_variant	1.0	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	1.0	rifampicin
rpoC	765811	c.2442T>G	synonymous_variant	1.0	rifampicin
rpoC	765826	c.2457T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765835	c.2466C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765871	c.2502T>C	synonymous_variant	0.94	rifampicin
rpoC	765886	c.2517C>G	synonymous_variant	1.0	rifampicin
rpoC	765967	c.2598C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765973	c.2604C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765982	c.2613C>G	synonymous_variant	1.0	rifampicin
rpoC	765994	c.2625A>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766010	c.2641_2642delTCinsAG	synonymous_variant	1.0	rifampicin
rpoC	766021	c.2652G>C	synonymous_variant	1.0	rifampicin
rpoC	766027	c.2658G>C	synonymous_variant	0.86	rifampicin
rpoC	766528	c.3159T>C	synonymous_variant	1.0	rifampicin
rpoC	766531	c.3162G>T	synonymous_variant	0.54	rifampicin
rpoC	766573	c.3204T>C	synonymous_variant	1.0	rifampicin
rpoC	766591	c.3222A>G	synonymous_variant	0.73	rifampicin
rpoC	766594	c.3225G>T	synonymous_variant	0.79	rifampicin
rpoC	766607	p.Ile1080Leu	missense_variant	1.0	rifampicin
rpoC	766651	c.3282T>C	synonymous_variant	1.0	rifampicin
rpoC	766657	c.3288A>G	synonymous_variant	1.0	rifampicin
rpoC	766666	c.3297C>G	synonymous_variant	0.71	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	1.0	rifampicin
rpoC	766711	c.3342C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	766726	c.3357T>C	synonymous_variant	1.0	rifampicin
rpoC	766738	c.3369G>C	synonymous_variant	0.84	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766774	c.3405T>C	synonymous_variant	1.0	rifampicin
rpoC	766801	c.3432C>T	synonymous_variant	0.93	rifampicin
rpoC	766804	c.3435A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766813	c.3444G>C	synonymous_variant	0.93	rifampicin
rpoC	766861	c.3492G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766864	c.3495G>C	synonymous_variant	0.94	rifampicin
rpoC	766894	c.3525T>C	synonymous_variant	1.0	rifampicin
rpoC	766895	c.3526T>C	synonymous_variant	1.0	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	1.0	rifampicin
rpoC	766903	c.3534C>T	synonymous_variant	1.0	rifampicin
rpoC	766933	c.3564A>G	synonymous_variant	1.0	rifampicin
rpoC	766945	c.3576A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766963	c.3594T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766972	c.3603G>C	synonymous_variant	1.0	rifampicin
rpoC	766978	c.3609C>A	synonymous_variant	1.0	rifampicin
rpoC	766996	c.3627C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767033	c.3664_3666delTCGinsAGT	synonymous_variant	0.75	rifampicin
rpoC	767059	c.3690T>G	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoC	767062	c.3693C>A	synonymous_variant	0.8	rifampicin
rpoC	767098	c.3729T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767119	c.3750A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	767134	c.3765C>A	synonymous_variant	0.85	rifampicin
rpoC	767167	c.3798C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	767180	p.Ala1271Gln	missense_variant	0.96	rifampicin
rpoC	767191	c.3822C>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	767206	c.3837C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767209	c.3840T>G	synonymous_variant	1.0	rifampicin
rpoC	767212	c.3843G>C	synonymous_variant	1.0	rifampicin
rpoC	767221	c.3852C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mmpL5	775912	c.2569C>A	synonymous_variant	0.9	bedaquiline
mmpL5	775912	c.2569C>A	synonymous_variant	0.9	clofazimine
mmpL5	775916	c.2565T>G	synonymous_variant	1.0	bedaquiline
mmpL5	775916	c.2565T>G	synonymous_variant	1.0	clofazimine
mmpL5	775922	c.2559G>C	synonymous_variant	0.92	bedaquiline
mmpL5	775922	c.2559G>C	synonymous_variant	0.92	clofazimine
mmpL5	775937	c.2544G>C	synonymous_variant	1.0	bedaquiline
mmpL5	775937	c.2544G>C	synonymous_variant	1.0	clofazimine
mmpL5	775966	p.Ala839Ser	missense_variant	1.0	bedaquiline
mmpL5	775966	p.Ala839Ser	missense_variant	1.0	clofazimine
mmpL5	775975	c.2506T>C	synonymous_variant	1.0	bedaquiline
mmpL5	775975	c.2506T>C	synonymous_variant	1.0	clofazimine
mmpL5	775981	p.Leu834Met	missense_variant	1.0	bedaquiline
mmpL5	775981	p.Leu834Met	missense_variant	1.0	clofazimine
mmpL5	775991	c.2490G>A	synonymous_variant	0.94	bedaquiline
mmpL5	775991	c.2490G>A	synonymous_variant	0.94	clofazimine
mmpL5	776000	p.Leu827Ile	missense_variant	1.0	bedaquiline
mmpL5	776000	p.Leu827Ile	missense_variant	1.0	clofazimine
mmpL5	776005	p.Ile826Leu	missense_variant	0.93	bedaquiline
mmpL5	776005	p.Ile826Leu	missense_variant	0.93	clofazimine
mmpL5	776030	c.2451G>C	synonymous_variant	0.9	bedaquiline
mmpL5	776030	c.2451G>C	synonymous_variant	0.9	clofazimine
rpsL	781628	c.69T>C	synonymous_variant	0.91	streptomycin	Not assoc w R - Interim
rpsL	781649	c.90T>C	synonymous_variant	0.94	streptomycin
rpsL	781655	c.96T>C	synonymous_variant	0.94	streptomycin
rpsL	781682	c.123T>C	synonymous_variant	0.8	streptomycin
rpsL	781715	c.156T>C	synonymous_variant	0.91	streptomycin
rpsL	781724	c.165G>C	synonymous_variant	0.9	streptomycin
rpsL	781728	c.169T>C	synonymous_variant	0.91	streptomycin
rpsL	781733	c.174G>C	synonymous_variant	0.91	streptomycin
rpsL	781736	c.177T>C	synonymous_variant	0.91	streptomycin
rpsL	781742	c.183C>T	synonymous_variant	0.92	streptomycin
rpsL	781751	c.192G>C	synonymous_variant	0.89	streptomycin
rpsL	781754	c.195G>C	synonymous_variant	0.78	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	0.9	streptomycin
rpsL	781763	c.204C>G	synonymous_variant	0.81	streptomycin
rpsL	781772	c.213C>G	synonymous_variant	0.92	streptomycin
rpsL	781808	c.249C>T	synonymous_variant	0.88	streptomycin
rpsL	781814	c.255C>G	synonymous_variant	0.87	streptomycin
rpsL	781817	c.258G>A	synonymous_variant	0.86	streptomycin
rpsL	781820	c.261G>C	synonymous_variant	0.86	streptomycin
rpsL	781832	c.273T>C	synonymous_variant	0.95	streptomycin
rpsL	781838	c.279G>C	synonymous_variant	0.89	streptomycin
rpsL	781841	c.282C>G	synonymous_variant	0.94	streptomycin
rpsL	781853	c.294C>T	synonymous_variant	0.93	streptomycin
rpsL	781859	c.300T>C	synonymous_variant	1.0	streptomycin	Not assoc w R - Interim
rpsL	781880	c.321C>G	synonymous_variant	0.92	streptomycin
rplC	800537	c.-272C>T	upstream_gene_variant	0.82	linezolid
rplC	800546	c.-263T>G	upstream_gene_variant	1.0	linezolid
rplC	800567	c.-242A>G	upstream_gene_variant	1.0	linezolid
rplC	800582	c.-227C>G	upstream_gene_variant	0.81	linezolid
rplC	800591	c.-218C>T	upstream_gene_variant	0.87	linezolid
rplC	800594	c.-215C>T	upstream_gene_variant	1.0	linezolid
rplC	800600	c.-209G>T	upstream_gene_variant	1.0	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	1.0	linezolid
rplC	800648	c.-161A>G	upstream_gene_variant	1.0	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.93	linezolid
rplC	800690	c.-119C>T	upstream_gene_variant	0.85	linezolid
rplC	800693	c.-116A>G	upstream_gene_variant	0.92	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.92	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	0.92	linezolid
rplC	800720	c.-89T>C	upstream_gene_variant	0.92	linezolid
rplC	800747	c.-62C>G	upstream_gene_variant	0.9	linezolid
rplC	800771	c.-38C>T	upstream_gene_variant	0.85	linezolid
rplC	800806	c.-3G>C	upstream_gene_variant	0.8	linezolid
rplC	800807	c.-2C>T	upstream_gene_variant	0.8	linezolid
rplC	800808	c.-1A>C	upstream_gene_variant	0.8	linezolid	Uncertain significance
rplC	800815	c.7C>A	synonymous_variant	0.9	linezolid
rplC	800820	c.12G>A	synonymous_variant	0.8	linezolid
rplC	800829	c.21C>G	synonymous_variant	0.82	linezolid
rplC	800844	c.36T>C	synonymous_variant	0.75	linezolid
rplC	800856	c.48A>G	synonymous_variant	0.8	linezolid
rplC	801171	c.363A>G	synonymous_variant	1.0	linezolid
rplC	801174	c.366T>C	synonymous_variant	0.94	linezolid
rplC	801195	c.387G>C	synonymous_variant	0.95	linezolid
rplC	801246	c.438C>T	synonymous_variant	1.0	linezolid
rplC	801249	c.441T>C	synonymous_variant	0.94	linezolid
rplC	801255	c.447C>T	synonymous_variant	1.0	linezolid
rplC	801357	c.549T>C	synonymous_variant	1.0	linezolid
rplC	801367	p.Ala187Thr	missense_variant	1.0	linezolid
fbiC	1303521	c.591C>T	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1303534	p.Ser202Ala	missense_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1303545	c.615A>G	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1303575	c.645G>C	synonymous_variant	0.89	pretomanid
					delamanid
					clofazimine
fbiC	1303584	c.654C>G	synonymous_variant	0.86	pretomanid
					delamanid
					clofazimine
fbiC	1303587	c.657G>A	synonymous_variant	0.85	pretomanid
					delamanid
					clofazimine
fbiC	1303590	c.660A>G	synonymous_variant	0.85	pretomanid
					delamanid
					clofazimine
fbiC	1303632	c.702T>G	synonymous_variant	0.9	pretomanid
					delamanid
					clofazimine
fbiC	1303641	c.711C>T	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1303647	c.717G>C	synonymous_variant	0.9	pretomanid
					delamanid
					clofazimine
fbiC	1303695	c.765T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303704	c.774T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303708	c.778T>C	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1303716	c.786C>A	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1303728	c.798G>C	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1303731	c.801A>C	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1303732	p.Ser268Ala	missense_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1303737	c.807G>A	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1303746	c.816T>C	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1303752	c.822A>G	synonymous_variant	0.95	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1303785	c.855G>A	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1303788	c.858T>C	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1303789	p.Ile287Val	missense_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1303812	c.882C>T	synonymous_variant	0.96	pretomanid
					delamanid
					clofazimine
fbiC	1303821	c.891C>G	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1303845	c.915C>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1303846	p.Phe306Val	missense_variant	0.9	pretomanid
					delamanid
					clofazimine
fbiC	1303854	c.924T>C	synonymous_variant	0.96	pretomanid
					delamanid
					clofazimine
fbiC	1303860	c.930A>C	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1303884	c.954T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303890	c.960G>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303897	c.967C>T	synonymous_variant	1.0	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1303902	c.972G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303908	c.978C>T	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1303911	c.981G>C	synonymous_variant	0.9	pretomanid
					delamanid
					clofazimine
fbiC	1304772	c.1842C>T	synonymous_variant	0.79	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1304778	c.1848T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304784	c.1854T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304787	c.1857T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304796	c.1866G>A	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1304808	c.1878C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304811	c.1881C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304817	c.1887T>C	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1304829	c.1899T>C	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1304832	c.1902C>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304853	c.1923C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304856	c.1926C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304916	c.1986T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305276	c.2346G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305279	p.His783Gln	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305300	c.2370A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305303	c.2373T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305306	c.2376A>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305310	p.Arg794Glu	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305331	p.Glu801Asn	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305336	c.2406T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305348	c.2418C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305349	c.2419C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305396	c.2466C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305405	c.2475A>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
sigE	1365015	c.603G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365024	c.612T>C	synonymous_variant	1.0	pyrazinamide
sigE	1365033	c.621G>A	synonymous_variant	1.0	pyrazinamide
sigE	1365042	c.630G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365063	c.651A>C	synonymous_variant	1.0	pyrazinamide
sigE	1365072	c.660G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365075	c.663G>A	synonymous_variant	1.0	pyrazinamide
sigE	1365081	c.669G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365084	c.672G>T	synonymous_variant	1.0	pyrazinamide
sigE	1365090	c.678T>C	synonymous_variant	1.0	pyrazinamide
sigE	1365096	c.684G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365099	c.687A>C	synonymous_variant	1.0	pyrazinamide
atpE	1460816	c.-229T>C	upstream_gene_variant	1.0	bedaquiline
atpE	1460831	c.-214T>C	upstream_gene_variant	1.0	bedaquiline
atpE	1460840	c.-205A>C	upstream_gene_variant	1.0	bedaquiline
atpE	1460852	c.-193C>G	upstream_gene_variant	1.0	bedaquiline
atpE	1460855	c.-190T>C	upstream_gene_variant	1.0	bedaquiline
atpE	1460858	c.-187C>G	upstream_gene_variant	1.0	bedaquiline
atpE	1460882	c.-163T>C	upstream_gene_variant	1.0	bedaquiline
atpE	1460894	c.-151A>G	upstream_gene_variant	1.0	bedaquiline
atpE	1460897	c.-148A>C	upstream_gene_variant	0.78	bedaquiline
atpE	1460900	c.-145T>C	upstream_gene_variant	1.0	bedaquiline
atpE	1460915	c.-130C>G	upstream_gene_variant	0.64	bedaquiline
atpE	1461189	c.145C>T	synonymous_variant	1.0	bedaquiline
atpE	1461194	c.150C>T	synonymous_variant	1.0	bedaquiline
atpE	1461197	c.153A>G	synonymous_variant	1.0	bedaquiline
atpE	1461219	c.175T>C	synonymous_variant	1.0	bedaquiline
rrs	1471923	n.78T>C	non_coding_transcript_exon_variant	0.95	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471934	n.89A>G	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471969	n.124T>C	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1471970	n.125G>A	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472027	n.182C>T	non_coding_transcript_exon_variant	0.35	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472028	n.183A>T	non_coding_transcript_exon_variant	0.93	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472029	n.184C>T	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472030	n.185G>T	non_coding_transcript_exon_variant	0.59	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472031	n.186G>A	non_coding_transcript_exon_variant	0.95	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472034	n.189T>C	non_coding_transcript_exon_variant	0.59	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472044	n.199G>T	non_coding_transcript_exon_variant	0.68	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472053	n.211_212delGC	non_coding_transcript_exon_variant	0.95	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472100	n.255T>C	non_coding_transcript_exon_variant	0.29	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472106	n.261G>A	non_coding_transcript_exon_variant	0.39	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472113	n.268T>C	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472127	n.282C>T	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472129	n.284G>C	non_coding_transcript_exon_variant	0.54	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472137	n.292G>A	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472150	n.305T>A	non_coding_transcript_exon_variant	0.69	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472151	n.306C>A	non_coding_transcript_exon_variant	0.71	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472172	n.327T>C	non_coding_transcript_exon_variant	0.78	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472203	n.358G>A	non_coding_transcript_exon_variant	0.75	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472210	n.365A>C	non_coding_transcript_exon_variant	0.77	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472213	n.368G>C	non_coding_transcript_exon_variant	0.77	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472215	n.370A>G	non_coding_transcript_exon_variant	0.78	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472234	n.389T>C	non_coding_transcript_exon_variant	0.68	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472236	n.391C>G	non_coding_transcript_exon_variant	0.67	kanamycin
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472240	n.395G>A	non_coding_transcript_exon_variant	0.67	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472251	n.406G>A	non_coding_transcript_exon_variant	0.41	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472530	n.685G>A	non_coding_transcript_exon_variant	0.37	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472537	n.692C>T	non_coding_transcript_exon_variant	0.36	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472544	n.699C>G	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472545	n.700A>T	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472557	n.712G>A	non_coding_transcript_exon_variant	0.54	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472570	n.725G>A	non_coding_transcript_exon_variant	0.58	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472571	n.726G>C	non_coding_transcript_exon_variant	0.57	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472573	n.728C>T	non_coding_transcript_exon_variant	0.57	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472581	n.736A>T	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472598	n.753A>C	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472616	n.771G>A	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472734	n.889C>T	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472741	n.896G>A	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472744	n.899A>G	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472767	n.922G>A	non_coding_transcript_exon_variant	0.56	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472779	n.934G>A	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472781	n.936C>T	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472786	n.941C>T	non_coding_transcript_exon_variant	0.58	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472793	n.948A>T	non_coding_transcript_exon_variant	0.58	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472803	n.958T>A	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472969	n.1124A>G	non_coding_transcript_exon_variant	0.93	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472970	n.1125C>G	non_coding_transcript_exon_variant	0.93	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472977	n.1132G>C	non_coding_transcript_exon_variant	0.88	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472978	n.1133T>C	non_coding_transcript_exon_variant	0.94	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473035	n.1190G>A	non_coding_transcript_exon_variant	0.42	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473053	n.1208T>A	non_coding_transcript_exon_variant	0.39	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473056	n.1211A>T	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473062	n.1217T>A	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473068	n.1223A>G	non_coding_transcript_exon_variant	0.37	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473070	n.1225G>A	non_coding_transcript_exon_variant	0.37	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473089	n.1244A>C	non_coding_transcript_exon_variant	0.34	kanamycin
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473093	n.1248C>A	non_coding_transcript_exon_variant	0.31	kanamycin
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	0.68	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473105	n.1260G>A	non_coding_transcript_exon_variant	0.62	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTT	non_coding_transcript_exon_variant	0.95	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	0.82	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	0.81	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473290	n.1445C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrl	1473756	n.99G>A	non_coding_transcript_exon_variant	0.74	capreomycin
rrl	1473756	n.99G>A	non_coding_transcript_exon_variant	0.74	linezolid
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.76	capreomycin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.76	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473813	n.156C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473813	n.156C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473839	n.182G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473839	n.182G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473877	n.220G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473877	n.220G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473899	n.242A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473899	n.242A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473944	n.287G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473944	n.287G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473971	n.314G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473971	n.314G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473981	n.324_325insT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473981	n.324_325insT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	1.0	linezolid	Not assoc w R
rrl	1474009	n.352A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474009	n.352A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474012	n.355C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474012	n.355C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474036	n.379G>A	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1474036	n.379G>A	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474040	n.383G>A	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1474040	n.383G>A	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474054	n.397T>C	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1474054	n.397T>C	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1474061	n.404T>C	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1474061	n.404T>C	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474104	n.447G>T	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474104	n.447G>T	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474110	n.453A>G	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1474110	n.453A>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.67	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.67	linezolid	Uncertain significance
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	0.83	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474790	n.1133C>T	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1474790	n.1133C>T	non_coding_transcript_exon_variant	0.39	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.52	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.52	linezolid	Uncertain significance
rrl	1474798	n.1141C>T	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1474798	n.1141C>T	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1474804	n.1147C>T	non_coding_transcript_exon_variant	0.56	capreomycin	Uncertain significance
rrl	1474804	n.1147C>T	non_coding_transcript_exon_variant	0.56	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	0.3	linezolid	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474827	n.1170C>T	non_coding_transcript_exon_variant	0.67	capreomycin	Uncertain significance
rrl	1474827	n.1170C>T	non_coding_transcript_exon_variant	0.67	linezolid	Uncertain significance
rrl	1474831	n.1174A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474831	n.1174A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474844	n.1187G>T	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1474844	n.1187G>T	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1474866	n.1209C>A	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1474866	n.1209C>A	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1474896	n.1239A>G	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1474896	n.1239A>G	non_coding_transcript_exon_variant	0.6	linezolid	Uncertain significance
rrl	1474902	n.1245T>C	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1474902	n.1245T>C	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1474904	n.1247G>A	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1474904	n.1247G>A	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1474913	n.1256T>A	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1474913	n.1256T>A	non_coding_transcript_exon_variant	0.4	linezolid	Uncertain significance
rrl	1474920	n.1263G>A	non_coding_transcript_exon_variant	0.35	capreomycin	Uncertain significance
rrl	1474920	n.1263G>A	non_coding_transcript_exon_variant	0.35	linezolid	Uncertain significance
rrl	1474956	n.1299C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474956	n.1299C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474961	n.1304T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474961	n.1304T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474963	n.1306G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474963	n.1306G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474964	n.1307T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474964	n.1307T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474970	n.1313G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474970	n.1313G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475006	n.1349A>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475006	n.1349A>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475013	n.1356G>A	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475013	n.1356G>A	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475088	n.1431A>T	non_coding_transcript_exon_variant	0.85	capreomycin
rrl	1475088	n.1431A>T	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.69	capreomycin
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.69	linezolid
rrl	1475201	n.1544G>A	non_coding_transcript_exon_variant	0.69	capreomycin
rrl	1475201	n.1544G>A	non_coding_transcript_exon_variant	0.69	linezolid
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.71	linezolid
rrl	1475209	n.1552G>A	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1475209	n.1552G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	0.75	capreomycin	Uncertain significance
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	0.75	linezolid
rrl	1475249	n.1592T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1475249	n.1592T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1475252	n.1595C>T	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1475252	n.1595C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1475266	n.1609T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1475266	n.1609T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1475267	n.1610G>A	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1475267	n.1610G>A	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1475275	n.1618C>T	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1475275	n.1618C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1475276	n.1619T>C	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1475276	n.1619T>C	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475313	n.1656G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475313	n.1656G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475333	n.1676T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475333	n.1676T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475401	n.1745delC	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475401	n.1745delC	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475405	n.1748A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475405	n.1748A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475599	n.1942A>G	non_coding_transcript_exon_variant	0.71	capreomycin
rrl	1475599	n.1942A>G	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475621	n.1964T>C	non_coding_transcript_exon_variant	0.32	capreomycin	Uncertain significance
rrl	1475621	n.1964T>C	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1475638	n.1981C>T	non_coding_transcript_exon_variant	0.72	capreomycin
rrl	1475638	n.1981C>T	non_coding_transcript_exon_variant	0.72	linezolid
rrl	1475642	n.1985T>C	non_coding_transcript_exon_variant	0.7	capreomycin
rrl	1475642	n.1985T>C	non_coding_transcript_exon_variant	0.7	linezolid
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	0.32	capreomycin
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	0.61	capreomycin
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	0.61	linezolid
rrl	1475659	n.2002G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475659	n.2002G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475761	n.2104_2106delCGCinsGT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475761	n.2104_2106delCGCinsGT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475765	n.2111delG	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475765	n.2111delG	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475803	n.2146T>C	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1475803	n.2146T>C	non_coding_transcript_exon_variant	0.39	linezolid	Uncertain significance
rrl	1475804	n.2147G>C	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1475804	n.2147G>C	non_coding_transcript_exon_variant	0.39	linezolid	Uncertain significance
rrl	1475816	n.2159C>G	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1475816	n.2159C>G	non_coding_transcript_exon_variant	0.38	linezolid	Uncertain significance
rrl	1475817	n.2160A>G	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1475817	n.2160A>G	non_coding_transcript_exon_variant	0.38	linezolid	Uncertain significance
rrl	1475843	n.2186G>A	non_coding_transcript_exon_variant	0.35	capreomycin	Uncertain significance
rrl	1475843	n.2186G>A	non_coding_transcript_exon_variant	0.35	linezolid	Uncertain significance
rrl	1475853	n.2196C>T	non_coding_transcript_exon_variant	0.31	capreomycin	Uncertain significance
rrl	1475853	n.2196C>T	non_coding_transcript_exon_variant	0.31	linezolid	Uncertain significance
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.93	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.69	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.69	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.69	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.69	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476246	n.2589G>A	non_coding_transcript_exon_variant	0.32	capreomycin
rrl	1476246	n.2589G>A	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1476251	n.2594T>C	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1476251	n.2594T>C	non_coding_transcript_exon_variant	0.38	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476297	n.2640C>T	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1476297	n.2640C>T	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1476299	n.2642C>T	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1476299	n.2642C>T	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.59	capreomycin	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.59	linezolid	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.69	capreomycin	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.69	linezolid	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.72	capreomycin	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.72	linezolid	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.76	capreomycin	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.76	linezolid	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.76	capreomycin	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.76	linezolid	Uncertain significance
rrl	1476408	n.2751G>A	non_coding_transcript_exon_variant	0.79	capreomycin	Uncertain significance
rrl	1476408	n.2751G>A	non_coding_transcript_exon_variant	0.79	linezolid	Uncertain significance
rrl	1476425	n.2768G>A	non_coding_transcript_exon_variant	0.79	capreomycin	Uncertain significance
rrl	1476425	n.2768G>A	non_coding_transcript_exon_variant	0.79	linezolid	Uncertain significance
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.77	capreomycin	Not assoc w R
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.77	linezolid	Uncertain significance
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.71	capreomycin	Not assoc w R
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.63	capreomycin	Not assoc w R
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.63	linezolid	Uncertain significance
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.41	capreomycin	Not assoc w R
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	0.42	capreomycin	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	0.42	linezolid	Uncertain significance
rrl	1476573	n.2916A>T	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1476573	n.2916A>T	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1476577	n.2920T>G	non_coding_transcript_exon_variant	0.39	capreomycin	Uncertain significance
rrl	1476577	n.2920T>G	non_coding_transcript_exon_variant	0.39	linezolid	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	0.51	linezolid
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.43	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	0.38	capreomycin	Not assoc w R
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	0.38	linezolid	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	0.6	linezolid
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	0.42	capreomycin	Uncertain significance
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	0.42	linezolid	Uncertain significance
rrl	1476607	n.2950C>T	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1476607	n.2950C>T	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476614	n.2957A>G	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1476614	n.2957A>G	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.47	capreomycin	Not assoc w R
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.47	linezolid	Uncertain significance
rrl	1476624	n.2967T>A	non_coding_transcript_exon_variant	0.47	capreomycin	Uncertain significance
rrl	1476624	n.2967T>A	non_coding_transcript_exon_variant	0.47	linezolid	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476630	n.2973A>G	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1476630	n.2973A>G	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1476637	n.2980C>G	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1476637	n.2980C>G	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.69	capreomycin
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.69	linezolid
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.69	capreomycin	Uncertain significance
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.69	linezolid
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.91	linezolid
inhA	1673633	c.-569G>A	upstream_gene_variant	1.0	isoniazid
inhA	1673633	c.-569G>A	upstream_gene_variant	1.0	ethionamide
inhA	1673724	c.-478A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673724	c.-478A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673733	c.-469G>C	upstream_gene_variant	0.64	isoniazid
inhA	1673733	c.-469G>C	upstream_gene_variant	0.64	ethionamide
inhA	1673748	c.-454A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673748	c.-454A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673749	c.-453_-452delAAinsCG	upstream_gene_variant	0.6	isoniazid
inhA	1673749	c.-453_-452delAAinsCG	upstream_gene_variant	0.6	ethionamide
inhA	1673758	c.-444A>G	upstream_gene_variant	0.6	isoniazid
inhA	1673758	c.-444A>G	upstream_gene_variant	0.6	ethionamide
inhA	1673763	c.-439C>G	upstream_gene_variant	0.6	isoniazid
inhA	1673763	c.-439C>G	upstream_gene_variant	0.6	ethionamide
inhA	1674037	c.-165_-163delCAGinsGCC	upstream_gene_variant	0.8	isoniazid
inhA	1674037	c.-165_-163delCAGinsGCC	upstream_gene_variant	0.8	ethionamide
inhA	1674054	c.-148T>C	upstream_gene_variant	0.8	isoniazid
inhA	1674054	c.-148T>C	upstream_gene_variant	0.8	ethionamide
inhA	1674060	c.-142A>G	upstream_gene_variant	0.82	isoniazid
inhA	1674060	c.-142A>G	upstream_gene_variant	0.82	ethionamide
inhA	1674079	c.-123C>G	upstream_gene_variant	0.92	isoniazid
inhA	1674079	c.-123C>G	upstream_gene_variant	0.92	ethionamide
inhA	1674084	c.-118C>G	upstream_gene_variant	0.75	isoniazid
inhA	1674084	c.-118C>G	upstream_gene_variant	0.75	ethionamide
inhA	1674480	c.279T>C	synonymous_variant	0.82	isoniazid
inhA	1674480	c.279T>C	synonymous_variant	0.82	ethionamide
inhA	1674486	c.285T>C	synonymous_variant	0.93	isoniazid
inhA	1674486	c.285T>C	synonymous_variant	0.93	ethionamide
inhA	1674489	c.288G>T	synonymous_variant	0.86	isoniazid
inhA	1674489	c.288G>T	synonymous_variant	0.86	ethionamide
inhA	1674501	c.300G>A	synonymous_variant	0.81	isoniazid
inhA	1674501	c.300G>A	synonymous_variant	0.81	ethionamide
inhA	1674507	c.306G>C	synonymous_variant	0.82	isoniazid
inhA	1674507	c.306G>C	synonymous_variant	0.82	ethionamide
inhA	1674537	c.336C>G	synonymous_variant	0.85	isoniazid
inhA	1674537	c.336C>G	synonymous_variant	0.85	ethionamide
inhA	1674540	c.339C>T	synonymous_variant	0.85	isoniazid
inhA	1674540	c.339C>T	synonymous_variant	0.85	ethionamide
inhA	1674542	p.Ala114Glu	missense_variant	0.95	isoniazid
inhA	1674542	p.Ala114Glu	missense_variant	0.95	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	0.96	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	0.96	ethionamide
inhA	1674555	c.354G>A	synonymous_variant	0.85	isoniazid	Not assoc w R - Interim
inhA	1674555	c.354G>A	synonymous_variant	0.85	ethionamide	Not assoc w R - Interim
inhA	1674561	c.360C>T	synonymous_variant	0.88	isoniazid
inhA	1674561	c.360C>T	synonymous_variant	0.88	ethionamide
inhA	1674573	c.372G>C	synonymous_variant	0.83	isoniazid
inhA	1674573	c.372G>C	synonymous_variant	0.83	ethionamide
inhA	1674582	c.381T>C	synonymous_variant	0.91	isoniazid
inhA	1674582	c.381T>C	synonymous_variant	0.91	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	0.95	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	0.95	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	0.95	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	0.95	ethionamide
inhA	1674601	p.Leu134Thr	missense_variant	0.9	isoniazid
inhA	1674601	p.Leu134Thr	missense_variant	0.9	ethionamide
inhA	1674624	c.423A>C	synonymous_variant	0.94	isoniazid
inhA	1674624	c.423A>C	synonymous_variant	0.94	ethionamide
inhA	1674627	c.426T>C	synonymous_variant	0.88	isoniazid
inhA	1674627	c.426T>C	synonymous_variant	0.88	ethionamide
inhA	1674636	c.435C>G	synonymous_variant	0.88	isoniazid
inhA	1674636	c.435C>G	synonymous_variant	0.88	ethionamide
inhA	1674654	c.453G>C	synonymous_variant	0.93	isoniazid
inhA	1674654	c.453G>C	synonymous_variant	0.93	ethionamide
inhA	1674660	c.459G>C	synonymous_variant	0.93	isoniazid
inhA	1674660	c.459G>C	synonymous_variant	0.93	ethionamide
inhA	1674846	p.Ile215Met	missense_variant	0.92	isoniazid
inhA	1674846	p.Ile215Met	missense_variant	0.92	ethionamide
inhA	1674849	c.648G>A	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
inhA	1674849	c.648G>A	synonymous_variant	0.92	ethionamide	Not assoc w R - Interim
inhA	1674858	c.657G>A	synonymous_variant	1.0	isoniazid
inhA	1674858	c.657G>A	synonymous_variant	1.0	ethionamide
inhA	1674870	c.669T>C	synonymous_variant	1.0	isoniazid
inhA	1674870	c.669T>C	synonymous_variant	1.0	ethionamide
inhA	1674873	c.672G>A	synonymous_variant	1.0	isoniazid
inhA	1674873	c.672G>A	synonymous_variant	1.0	ethionamide
inhA	1674879	c.678T>C	synonymous_variant	1.0	isoniazid
inhA	1674879	c.678T>C	synonymous_variant	1.0	ethionamide
inhA	1674903	c.702T>C	synonymous_variant	1.0	isoniazid
inhA	1674903	c.702T>C	synonymous_variant	1.0	ethionamide
inhA	1674904	p.Ala235Pro	missense_variant	1.0	isoniazid
inhA	1674904	p.Ala235Pro	missense_variant	1.0	ethionamide
inhA	1674934	c.733C>T	synonymous_variant	1.0	isoniazid
inhA	1674934	c.733C>T	synonymous_variant	1.0	ethionamide
inhA	1674939	c.738G>C	synonymous_variant	0.87	isoniazid
inhA	1674939	c.738G>C	synonymous_variant	0.87	ethionamide
inhA	1674942	c.741T>C	synonymous_variant	1.0	isoniazid
inhA	1674942	c.741T>C	synonymous_variant	1.0	ethionamide
inhA	1674960	c.759C>G	synonymous_variant	1.0	isoniazid
inhA	1674960	c.759C>G	synonymous_variant	1.0	ethionamide
rpsA	1833517	c.-24delC	upstream_gene_variant	1.0	pyrazinamide
rpsA	1833554	p.Thr5Ala	missense_variant	0.82	pyrazinamide	Uncertain significance
rpsA	1833589	c.48A>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833595	c.54T>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833604	c.63C>T	synonymous_variant	0.79	pyrazinamide
rpsA	1833667	c.126C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833703	c.162C>T	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1833721	c.180A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833742	c.201A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833745	c.204G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833760	c.219C>T	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1833772	c.231C>T	synonymous_variant	0.96	pyrazinamide
rpsA	1833782	p.Ser81Thr	missense_variant	0.96	pyrazinamide
rpsA	1833793	c.252C>T	synonymous_variant	0.96	pyrazinamide
rpsA	1833811	c.270G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833838	c.297G>T	synonymous_variant	0.95	pyrazinamide
rpsA	1833844	c.303C>T	synonymous_variant	0.95	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833901	c.360G>A	synonymous_variant	0.95	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833940	c.399C>G	synonymous_variant	0.95	pyrazinamide
rpsA	1833971	c.430C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833991	c.450C>A	synonymous_variant	0.94	pyrazinamide
rpsA	1834000	c.459G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834021	c.480C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834030	c.489C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834051	c.510G>A	synonymous_variant	0.89	pyrazinamide
rpsA	1834097	c.556_557delTCinsAG	synonymous_variant	0.82	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834252	c.711C>T	synonymous_variant	0.88	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834294	c.753G>T	synonymous_variant	0.9	pyrazinamide
rpsA	1834297	c.756C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834303	c.762T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834333	c.792C>T	synonymous_variant	0.92	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834366	c.825A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834369	c.828C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834375	c.834G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1834396	c.855G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834417	c.876G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834423	c.882G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834435	c.894G>C	synonymous_variant	0.85	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834468	c.927A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834474	c.933C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834477	c.936C>G	synonymous_variant	0.85	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834495	c.954G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1834498	c.957C>T	synonymous_variant	0.8	pyrazinamide
rpsA	1834528	c.987T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834540	c.999G>C	synonymous_variant	0.85	pyrazinamide
rpsA	1834546	c.1005T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834570	c.1029C>T	synonymous_variant	0.83	pyrazinamide	Not assoc w R - Interim
rpsA	1834606	c.1065C>G	synonymous_variant	0.9	pyrazinamide
rpsA	1834609	c.1068T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834633	c.1092A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834639	c.1098T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834690	c.1149T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834732	c.1191T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834738	c.1197A>G	synonymous_variant	0.87	pyrazinamide
rpsA	1834753	c.1212T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834756	c.1215G>A	synonymous_variant	0.94	pyrazinamide
rpsA	1834765	c.1224A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834780	c.1239A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834786	c.1245A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834789	c.1248T>C	synonymous_variant	1.0	pyrazinamide
bacA	2063565	c.1164C>T	synonymous_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2063588	c.1141T>C	synonymous_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2063610	p.Ser373Ala	missense_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2063613	c.1116T>G	synonymous_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2063625	c.1104G>T	synonymous_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2063628	c.1101C>G	synonymous_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2063640	c.1089C>T	synonymous_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
kasA	2517926	c.-189G>A	upstream_gene_variant	0.83	isoniazid
kasA	2517956	c.-159G>A	upstream_gene_variant	0.77	isoniazid
kasA	2517965	c.-150C>T	upstream_gene_variant	0.94	isoniazid
kasA	2517974	c.-141T>C	upstream_gene_variant	1.0	isoniazid
kasA	2517989	c.-126T>C	upstream_gene_variant	1.0	isoniazid
kasA	2517993	c.-122_-121delGCinsTA	upstream_gene_variant	0.6	isoniazid
kasA	2518162	c.48G>A	synonymous_variant	1.0	isoniazid
kasA	2518174	c.60A>G	synonymous_variant	1.0	isoniazid
kasA	2518183	c.69G>T	synonymous_variant	1.0	isoniazid
kasA	2518190	p.Ser26Ala	missense_variant	1.0	isoniazid
kasA	2518220	c.106C>T	synonymous_variant	1.0	isoniazid
kasA	2518459	c.345T>G	synonymous_variant	0.82	isoniazid
kasA	2518462	c.348A>C	synonymous_variant	0.91	isoniazid
kasA	2518468	c.354A>C	synonymous_variant	0.86	isoniazid
kasA	2518474	c.360G>A	synonymous_variant	0.67	isoniazid
kasA	2518475	c.361A>C	synonymous_variant	0.87	isoniazid
kasA	2518480	c.366T>C	synonymous_variant	0.93	isoniazid
kasA	2518483	c.369C>G	synonymous_variant	0.93	isoniazid
kasA	2518504	c.390T>C	synonymous_variant	0.92	isoniazid
kasA	2518506	p.Ala131Glu	missense_variant	0.92	isoniazid
kasA	2518519	c.405G>C	synonymous_variant	0.88	isoniazid
kasA	2518528	c.414C>G	synonymous_variant	0.89	isoniazid
kasA	2518534	c.420G>C	synonymous_variant	0.88	isoniazid
kasA	2518537	c.423C>G	synonymous_variant	0.75	isoniazid
kasA	2518561	c.447T>C	synonymous_variant	0.77	isoniazid
kasA	2518570	c.456G>C	synonymous_variant	0.79	isoniazid
kasA	2518574	p.Ile154Val	missense_variant	0.89	isoniazid
kasA	2518579	c.465T>A	synonymous_variant	0.89	isoniazid
kasA	2518582	c.468G>T	synonymous_variant	0.89	isoniazid
kasA	2518588	c.474T>C	synonymous_variant	0.89	isoniazid
kasA	2518591	c.477G>C	synonymous_variant	0.84	isoniazid
kasA	2518609	p.Met165Ile	missense_variant	0.81	isoniazid
kasA	2518618	c.504G>T	synonymous_variant	0.88	isoniazid
kasA	2518636	c.522C>T	synonymous_variant	0.79	isoniazid
kasA	2518657	c.543G>C	synonymous_variant	0.8	isoniazid
kasA	2518672	c.558G>C	synonymous_variant	0.85	isoniazid
kasA	2518678	c.564C>T	synonymous_variant	0.81	isoniazid
kasA	2518693	c.579C>G	synonymous_variant	0.82	isoniazid
kasA	2518696	c.582C>G	synonymous_variant	0.88	isoniazid
kasA	2518714	c.600A>C	synonymous_variant	0.94	isoniazid
kasA	2518732	c.618C>G	synonymous_variant	1.0	isoniazid
kasA	2518747	c.633C>G	synonymous_variant	1.0	isoniazid
kasA	2518768	c.654C>G	synonymous_variant	0.83	isoniazid
kasA	2518777	c.663C>T	synonymous_variant	0.86	isoniazid
kasA	2518789	c.675G>C	synonymous_variant	0.85	isoniazid
kasA	2518792	c.678C>A	synonymous_variant	1.0	isoniazid
kasA	2518795	c.681C>G	synonymous_variant	1.0	isoniazid
kasA	2518825	c.711T>C	synonymous_variant	1.0	isoniazid
kasA	2518834	c.720C>T	synonymous_variant	0.91	isoniazid
kasA	2518843	c.729T>G	synonymous_variant	0.95	isoniazid
kasA	2518864	c.750G>C	synonymous_variant	1.0	isoniazid
kasA	2518873	c.759C>T	synonymous_variant	0.92	isoniazid
kasA	2518879	c.765A>G	synonymous_variant	1.0	isoniazid
kasA	2518882	c.768C>A	synonymous_variant	0.9	isoniazid
kasA	2518885	c.771T>C	synonymous_variant	1.0	isoniazid
ahpC	2726348	c.156T>C	synonymous_variant	0.92	isoniazid
ahpC	2726357	c.165A>G	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
ahpC	2726366	c.174G>C	synonymous_variant	1.0	isoniazid
ahpC	2726369	c.177C>T	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
ahpC	2726378	c.186T>G	synonymous_variant	1.0	isoniazid
Rv2477c	2782450	c.1593C>A	synonymous_variant	0.92	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782483	c.1560G>C	synonymous_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782510	c.1533G>C	synonymous_variant	0.76	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782528	c.1515G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782540	c.1503T>C	synonymous_variant	0.62	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782549	c.1494T>C	synonymous_variant	0.92	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2477c	2782913	p.Ser377Thr	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782927	p.Thr372Gln	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2782936	c.1107G>T	synonymous_variant	0.9	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783140	c.903C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783149	c.894G>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol
					amikacin	Not assoc w R - Interim
Rv2477c	2783158	c.885A>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783182	c.861C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783194	c.849A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783203	c.840C>T	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783224	c.819C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783230	c.813T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783254	c.789A>G	synonymous_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783263	c.780G>C	synonymous_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783275	c.768C>G	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783278	c.765A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783287	c.756C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783293	p.Glu250Asp	missense_variant	0.79	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783299	c.744A>G	synonymous_variant	0.92	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783302	c.741A>G	synonymous_variant	0.93	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783311	c.732T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783332	c.711T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783341	c.702C>T	synonymous_variant	0.83	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783350	c.693T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783353	c.690T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783356	c.687C>G	synonymous_variant	0.8	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783359	c.684G>A	synonymous_variant	0.8	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783374	c.669G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783395	c.648T>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783410	c.633G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783446	c.597A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783461	c.582T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783464	c.579A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783467	c.576G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783473	c.570A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783499	c.544T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783611	c.432C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783620	c.423C>G	synonymous_variant	0.92	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783628	p.Ala139Ser	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783629	c.414C>T	synonymous_variant	0.86	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783656	c.387G>C	synonymous_variant	0.91	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783659	c.384A>G	synonymous_variant	0.91	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783665	c.378A>G	synonymous_variant	0.91	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783674	c.369T>C	synonymous_variant	0.96	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783683	c.360A>G	synonymous_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783691	c.352C>T	synonymous_variant	0.91	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783700	p.Thr115Ser	missense_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783719	c.324A>G	synonymous_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783746	c.297G>A	synonymous_variant	0.92	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783751	p.Ile98Val	missense_variant	0.91	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783846	p.Thr66Asn	missense_variant	0.7	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783863	c.180C>T	synonymous_variant	0.69	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783883	c.160T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783884	c.159T>C	synonymous_variant	0.92	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783914	c.129T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783920	c.123G>C	synonymous_variant	0.81	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783929	c.114C>G	synonymous_variant	0.84	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783932	c.111C>T	synonymous_variant	0.8	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783953	c.90G>A	synonymous_variant	0.8	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783962	c.81T>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783971	c.72G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783980	c.63C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783992	c.51T>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2477c	2784016	c.27G>A	synonymous_variant	0.7	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2752c	3065475	c.717C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065481	c.711T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065487	c.705T>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065493	c.699G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065496	c.696G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065499	c.693A>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065508	c.684T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065511	c.681G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065517	c.673_675delCTCinsTTG	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065532	c.660A>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065553	c.639A>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065562	c.630T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065568	p.Ile208Leu	missense_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065576	p.Ala206Ser	missense_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065577	c.615C>T	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065580	c.612G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065595	p.Leu199Phe	missense_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065607	c.585C>G	synonymous_variant	0.9	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066476	c.-285C>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066480	c.-291_-289delGCCinsTCT	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066501	c.-311_-310delCGinsTC	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066531	c.-340C>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066543	c.-352C>A	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066549	c.-358T>C	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066556	c.-365C>T	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066561	c.-370A>T	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066567	c.-376C>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066573	c.-382G>C	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066579	c.-388A>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066583	c.-392C>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066780	c.-589C>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066804	c.-613G>T	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066807	c.-616T>C	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066819	c.-628T>C	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066822	c.-631T>C	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066839	c.-648A>G	upstream_gene_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
thyX	3067243	c.703C>T	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067277	c.669C>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyX	3067284	p.Ala221Gly	missense_variant	0.94	para-aminosalicylic_acid
thyX	3067289	c.657C>G	synonymous_variant	0.88	para-aminosalicylic_acid
thyX	3067316	c.630A>G	synonymous_variant	0.9	para-aminosalicylic_acid
thyX	3067355	c.591A>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067367	c.579G>C	synonymous_variant	0.87	para-aminosalicylic_acid
thyX	3067373	c.573C>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067382	c.564C>T	synonymous_variant	0.86	para-aminosalicylic_acid
thyX	3067388	c.558C>G	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067394	c.552G>C	synonymous_variant	0.88	para-aminosalicylic_acid
thyX	3067430	c.516C>G	synonymous_variant	0.82	para-aminosalicylic_acid
thyX	3067649	c.297C>T	synonymous_variant	0.9	para-aminosalicylic_acid
thyX	3067658	c.288C>T	synonymous_variant	0.92	para-aminosalicylic_acid
thyX	3067661	c.285C>G	synonymous_variant	0.92	para-aminosalicylic_acid
thyX	3067667	c.279G>C	synonymous_variant	0.88	para-aminosalicylic_acid
thyX	3067694	c.252G>C	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067706	c.240C>T	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067715	c.231C>T	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067718	c.228C>G	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067721	c.225T>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067724	c.222G>A	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067727	c.219A>C	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067739	c.207T>C	synonymous_variant	0.79	para-aminosalicylic_acid
thyX	3067742	c.204A>C	synonymous_variant	0.92	para-aminosalicylic_acid
thyX	3067781	c.165C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067849	p.Pro33Ser	missense_variant	0.93	para-aminosalicylic_acid
thyX	3067850	c.96A>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067869	p.Thr26Ser	missense_variant	0.94	para-aminosalicylic_acid
thyX	3067874	c.72C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067883	c.63C>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyX	3067886	c.60A>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067889	c.57C>G	synonymous_variant	0.93	para-aminosalicylic_acid
thyA	3073898	p.Ala192Ser	missense_variant	1.0	para-aminosalicylic_acid
thyA	3073920	c.552C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073926	c.546G>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073929	c.543T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073953	c.519T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073977	c.495A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073983	c.489C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073989	c.483T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074004	c.468T>C	synonymous_variant	1.0	para-aminosalicylic_acid
lpqB	3623423	c.1488C>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
lpqB	3623423	c.1488C>G	synonymous_variant	0.9	bedaquiline
lpqB	3624680	c.231T>G	synonymous_variant	1.0	rifampicin
lpqB	3624680	c.231T>G	synonymous_variant	1.0	bedaquiline
lpqB	3624683	c.228G>C	synonymous_variant	0.85	rifampicin
lpqB	3624683	c.228G>C	synonymous_variant	0.85	bedaquiline
lpqB	3624686	p.Glu75Gln	missense_variant	1.0	rifampicin
lpqB	3624686	p.Glu75Gln	missense_variant	1.0	bedaquiline
lpqB	3624701	c.210T>C	synonymous_variant	1.0	rifampicin
lpqB	3624701	c.210T>C	synonymous_variant	1.0	bedaquiline
lpqB	3624704	c.207G>T	synonymous_variant	0.85	rifampicin
lpqB	3624704	c.207G>T	synonymous_variant	0.85	bedaquiline
lpqB	3624707	c.204G>C	synonymous_variant	0.92	rifampicin
lpqB	3624707	c.204G>C	synonymous_variant	0.92	bedaquiline
lpqB	3624728	c.183C>T	synonymous_variant	1.0	rifampicin
lpqB	3624728	c.183C>T	synonymous_variant	1.0	bedaquiline
mtrB	3625656	c.958T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrB	3625656	c.958T>C	synonymous_variant	0.93	bedaquiline	Not assoc w R - Interim
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.86	rifampicin
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.86	bedaquiline
lpqB	3625675	c.-765G>C	upstream_gene_variant	0.78	rifampicin
lpqB	3625675	c.-765G>C	upstream_gene_variant	0.78	bedaquiline
lpqB	3625696	c.-786A>G	upstream_gene_variant	0.83	rifampicin
lpqB	3625696	c.-786A>G	upstream_gene_variant	0.83	bedaquiline
mtrB	3625705	c.909C>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
mtrB	3625705	c.909C>G	synonymous_variant	0.83	bedaquiline
mtrB	3625708	c.906C>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrB	3625708	c.906C>T	synonymous_variant	0.92	bedaquiline
lpqB	3625714	c.-804C>T	upstream_gene_variant	0.86	rifampicin
lpqB	3625714	c.-804C>T	upstream_gene_variant	0.86	bedaquiline
mtrB	3625720	c.894G>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
mtrB	3625720	c.894G>C	synonymous_variant	0.83	bedaquiline
mtrB	3625729	c.885A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3625729	c.885A>G	synonymous_variant	0.96	bedaquiline
mtrB	3625732	c.882C>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
mtrB	3625732	c.882C>T	synonymous_variant	0.79	bedaquiline
lpqB	3625735	c.-825C>T	upstream_gene_variant	0.93	rifampicin
lpqB	3625735	c.-825C>T	upstream_gene_variant	0.93	bedaquiline
mtrB	3625755	p.Ala287Thr	missense_variant	0.87	rifampicin	Uncertain significance
mtrB	3625755	p.Ala287Thr	missense_variant	0.87	bedaquiline
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.96	rifampicin
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3625765	c.849C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
mtrB	3625765	c.849C>G	synonymous_variant	0.97	bedaquiline
mtrB	3625774	c.840G>A	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrB	3625774	c.840G>A	synonymous_variant	0.93	bedaquiline
mtrB	3625806	c.808A>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3625806	c.808A>C	synonymous_variant	0.96	bedaquiline
mtrB	3625852	c.762A>G	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
mtrB	3625852	c.762A>G	synonymous_variant	0.87	bedaquiline
mtrB	3625855	c.759G>A	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
mtrB	3625855	c.759G>A	synonymous_variant	0.88	bedaquiline
lpqB	3625864	c.-954T>G	upstream_gene_variant	0.93	rifampicin
lpqB	3625864	c.-954T>G	upstream_gene_variant	0.93	bedaquiline
mtrB	3626732	c.-119A>G	upstream_gene_variant	0.6	rifampicin
mtrB	3626732	c.-119A>G	upstream_gene_variant	0.6	bedaquiline
mtrB	3626735	c.-122C>T	upstream_gene_variant	0.6	rifampicin
mtrB	3626735	c.-122C>T	upstream_gene_variant	0.6	bedaquiline
mtrB	3626746	c.-133C>A	upstream_gene_variant	0.62	rifampicin
mtrB	3626746	c.-133C>A	upstream_gene_variant	0.62	bedaquiline
mtrA	3626765	c.585C>T	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
mtrA	3626765	c.585C>T	synonymous_variant	0.87	bedaquiline
mtrB	3626783	c.-170C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626783	c.-170C>G	upstream_gene_variant	1.0	bedaquiline
mtrA	3626804	c.546A>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
mtrA	3626804	c.546A>G	synonymous_variant	0.91	bedaquiline
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.69	rifampicin
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.69	bedaquiline
mtrA	3626846	c.504G>A	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrA	3626846	c.504G>A	synonymous_variant	0.93	bedaquiline
mtrB	3626876	c.-263A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626876	c.-263A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626891	c.-278G>C	upstream_gene_variant	0.58	rifampicin
mtrB	3626891	c.-278G>C	upstream_gene_variant	0.58	bedaquiline
mtrB	3626894	c.-281C>T	upstream_gene_variant	0.62	rifampicin
mtrB	3626894	c.-281C>T	upstream_gene_variant	0.62	bedaquiline
mtrB	3626903	c.-290T>C	upstream_gene_variant	0.58	rifampicin
mtrB	3626903	c.-290T>C	upstream_gene_variant	0.58	bedaquiline
mtrB	3627011	c.-398T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627011	c.-398T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627023	c.-410C>G	upstream_gene_variant	0.78	rifampicin
mtrB	3627023	c.-410C>G	upstream_gene_variant	0.78	bedaquiline
mtrB	3627065	c.-452G>C	upstream_gene_variant	0.67	rifampicin
mtrB	3627065	c.-452G>C	upstream_gene_variant	0.67	bedaquiline
mtrA	3627068	c.282T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrA	3627068	c.282T>C	synonymous_variant	0.92	bedaquiline
mtrB	3627074	c.-461G>C	upstream_gene_variant	0.59	rifampicin
mtrB	3627074	c.-461G>C	upstream_gene_variant	0.59	bedaquiline
mtrA	3627080	c.270T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
mtrA	3627080	c.270T>C	synonymous_variant	0.94	bedaquiline
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.94	rifampicin
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.94	bedaquiline
mtrA	3627098	c.252A>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrA	3627098	c.252A>C	synonymous_variant	0.93	bedaquiline
mtrA	3627101	c.249C>T	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
mtrA	3627101	c.249C>T	synonymous_variant	0.67	bedaquiline	Not assoc w R - Interim
mtrB	3627104	c.-491C>G	upstream_gene_variant	0.69	rifampicin
mtrB	3627104	c.-491C>G	upstream_gene_variant	0.69	bedaquiline
mtrA	3627119	c.231T>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrA	3627119	c.231T>G	synonymous_variant	0.92	bedaquiline
mtrA	3627137	c.213G>A	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
mtrA	3627137	c.213G>A	synonymous_variant	0.86	bedaquiline
mtrB	3627167	c.-554T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627167	c.-554T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627181	c.-568T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627181	c.-568T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627182	c.-569T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627182	c.-569T>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627188	c.162A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627188	c.162A>G	synonymous_variant	1.0	bedaquiline
mtrB	3627194	c.-583_-581delCTGinsTTA	upstream_gene_variant	1.0	rifampicin
mtrB	3627194	c.-583_-581delCTGinsTTA	upstream_gene_variant	1.0	bedaquiline
mtrA	3627208	c.142C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627208	c.142C>T	synonymous_variant	1.0	bedaquiline
mtrB	3627209	c.-596G>A	upstream_gene_variant	1.0	rifampicin
mtrB	3627209	c.-596G>A	upstream_gene_variant	1.0	bedaquiline
mtrA	3627221	c.129C>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrA	3627221	c.129C>T	synonymous_variant	0.93	bedaquiline
mtrA	3627227	c.123T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrA	3627227	c.123T>C	synonymous_variant	0.92	bedaquiline
mtrB	3627233	c.-620T>C	upstream_gene_variant	0.91	rifampicin
mtrB	3627233	c.-620T>C	upstream_gene_variant	0.91	bedaquiline
mtrB	3627236	c.-623T>C	upstream_gene_variant	0.92	rifampicin
mtrB	3627236	c.-623T>C	upstream_gene_variant	0.92	bedaquiline
mtrA	3627242	c.108C>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrA	3627242	c.108C>T	synonymous_variant	0.92	bedaquiline
mtrB	3627254	c.-641C>T	upstream_gene_variant	0.75	rifampicin
mtrB	3627254	c.-641C>T	upstream_gene_variant	0.75	bedaquiline
mtrB	3627266	c.-653A>G	upstream_gene_variant	0.91	rifampicin
mtrB	3627266	c.-653A>G	upstream_gene_variant	0.91	bedaquiline
mtrB	3627272	c.-659G>T	upstream_gene_variant	0.91	rifampicin
mtrB	3627272	c.-659G>T	upstream_gene_variant	0.91	bedaquiline
mtrB	3627275	c.-662G>T	upstream_gene_variant	0.91	rifampicin
mtrB	3627275	c.-662G>T	upstream_gene_variant	0.91	bedaquiline
mtrB	3627296	c.-683T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627296	c.-683T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627299	c.-688_-686delTTGinsCTA	upstream_gene_variant	0.85	rifampicin
mtrB	3627299	c.-688_-686delTTGinsCTA	upstream_gene_variant	0.85	bedaquiline
mtrB	3627314	c.-701C>T	upstream_gene_variant	0.88	rifampicin
mtrB	3627314	c.-701C>T	upstream_gene_variant	0.88	bedaquiline
mtrB	3627317	c.-704T>C	upstream_gene_variant	0.93	rifampicin
mtrB	3627317	c.-704T>C	upstream_gene_variant	0.93	bedaquiline
mtrA	3627342	p.Thr3Phe	missense_variant	0.82	rifampicin
mtrA	3627342	p.Thr3Phe	missense_variant	0.82	bedaquiline
mtrA	3627345	p.Asp2Val	missense_variant	0.82	rifampicin
mtrA	3627345	p.Asp2Val	missense_variant	0.82	bedaquiline
fbiB	3642656	c.1122G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642659	c.1125C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642662	c.1128C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642668	c.1134A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642677	c.1143A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642680	c.1146A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642684	c.1150T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642701	c.1167C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642711	p.Leu393Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642716	c.1182C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiB	3642719	c.1185T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
rpoA	3877542	c.966C>T	synonymous_variant	0.85	rifampicin
rpoA	3877553	p.Glu319Gln	missense_variant	0.85	rifampicin
rpoA	3877587	c.921A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877613	p.Ile299Val	missense_variant	0.92	rifampicin
rpoA	3877656	c.852T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoA	3877668	c.840A>G	synonymous_variant	0.94	rifampicin
rpoA	3877677	p.Ala277Ser	missense_variant	0.8	rifampicin
rpoA	3877680	c.828G>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoA	3877686	c.822A>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoA	3877692	c.816G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877704	c.804G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoA	3877746	c.762G>T	synonymous_variant	0.88	rifampicin
rpoA	3877764	c.744C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877770	c.738A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877776	c.732T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877782	c.726T>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoA	3877818	c.690A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3877829	p.Val227Ile	missense_variant	0.96	rifampicin
rpoA	3877839	c.669G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3877857	c.651G>A	synonymous_variant	1.0	rifampicin
rpoA	3877866	c.642G>C	synonymous_variant	0.96	rifampicin
rpoA	3877872	c.636C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877875	c.633T>G	synonymous_variant	1.0	rifampicin
rpoA	3877896	c.612G>C	synonymous_variant	1.0	rifampicin
rpoA	3877900	p.Ser203Asn	missense_variant	1.0	rifampicin
rpoA	3877905	c.603A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877908	p.Asn200Ser	missense_variant	1.0	rifampicin
rpoA	3877920	c.588G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877962	c.546G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877983	c.525C>T	synonymous_variant	1.0	rifampicin
rpoA	3877986	c.522G>C	synonymous_variant	1.0	rifampicin
rpoA	3877989	c.519A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878001	c.507A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878022	c.486T>C	synonymous_variant	0.93	rifampicin
rpoA	3878025	c.483C>T	synonymous_variant	0.92	rifampicin
rpoA	3878028	c.480G>C	synonymous_variant	0.92	rifampicin
rpoA	3878031	c.477T>C	synonymous_variant	0.92	rifampicin
rpoA	3878040	c.468T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoA	3878055	c.453A>G	synonymous_variant	0.91	rifampicin
rpoA	3878061	c.447G>C	synonymous_variant	0.9	rifampicin
rpoA	3878148	c.360C>T	synonymous_variant	1.0	rifampicin
rpoA	3878163	c.345C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878166	c.342C>G	synonymous_variant	0.93	rifampicin
rpoA	3878169	c.339G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878184	c.324C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878187	c.321C>G	synonymous_variant	0.94	rifampicin
rpoA	3878193	c.315T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878217	c.291A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878271	c.237T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoA	3878276	c.232C>T	synonymous_variant	0.69	rifampicin	Not assoc w R - Interim
rpoA	3878284	p.Glu75Ala	missense_variant	0.93	rifampicin
rpoA	3878292	c.216T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoA	3878298	c.210A>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoA	3878304	c.204G>C	synonymous_variant	0.93	rifampicin
rpoA	3878307	c.201C>G	synonymous_variant	0.79	rifampicin
rpoA	3878313	c.195G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878322	c.186A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878331	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878334	c.174T>C	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoA	3878337	c.171T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878364	c.144A>T	synonymous_variant	1.0	rifampicin
rpoA	3878367	c.141C>G	synonymous_variant	0.92	rifampicin
rpoA	3878376	c.132G>C	synonymous_variant	0.92	rifampicin
rpoA	3878385	c.123C>G	synonymous_variant	1.0	rifampicin
rpoA	3878415	c.93C>T	synonymous_variant	0.9	rifampicin
rpoA	3878436	c.72A>G	synonymous_variant	0.8	rifampicin
rpoA	3878909	c.-402A>G	upstream_gene_variant	0.88	rifampicin
rpoA	3878914	c.-407T>C	upstream_gene_variant	0.88	rifampicin	Uncertain significance
rpoA	3878917	c.-410G>A	upstream_gene_variant	0.88	rifampicin	Uncertain significance
rpoA	3878935	c.-428C>T	upstream_gene_variant	0.87	rifampicin
rpoA	3878938	c.-431T>G	upstream_gene_variant	0.86	rifampicin
rpoA	3878962	c.-455G>T	upstream_gene_variant	0.88	rifampicin
rpoA	3878968	c.-461T>C	upstream_gene_variant	0.88	rifampicin	Uncertain significance
rpoA	3878974	c.-469_-467delATCinsGTG	upstream_gene_variant	0.83	rifampicin
rpoA	3878998	c.-491C>G	upstream_gene_variant	0.93	rifampicin	Uncertain significance
rpoA	3879004	c.-499_-497delAAGinsCGC	upstream_gene_variant	0.73	rifampicin
rpoA	3879016	c.-509A>G	upstream_gene_variant	0.91	rifampicin
rpoA	3879019	c.-512T>C	upstream_gene_variant	0.69	rifampicin
rpoA	3879022	c.-515G>C	upstream_gene_variant	0.92	rifampicin
rpoA	3879033	c.-526C>T	upstream_gene_variant	0.67	rifampicin
rpoA	3879040	c.-535_-533delGTGinsTCC	upstream_gene_variant	0.67	rifampicin
rpoA	3879050	c.-543A>C	upstream_gene_variant	0.75	rifampicin
rpoA	3879094	c.-587T>C	upstream_gene_variant	0.92	rifampicin
rpoA	3879121	c.-614T>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879124	c.-617G>C	upstream_gene_variant	0.88	rifampicin
rpoA	3879127	c.-620T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879136	c.-629A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879154	c.-647T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879160	c.-653A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879190	c.-683C>G	upstream_gene_variant	1.0	rifampicin
ddn	3986636	c.-208C>G	upstream_gene_variant	1.0	pretomanid
ddn	3986636	c.-208C>G	upstream_gene_variant	1.0	delamanid
ddn	3986637	c.-207C>T	upstream_gene_variant	1.0	pretomanid
ddn	3986637	c.-207C>T	upstream_gene_variant	1.0	delamanid
ddn	3986645	c.-199G>A	upstream_gene_variant	1.0	pretomanid
ddn	3986645	c.-199G>A	upstream_gene_variant	1.0	delamanid
ddn	3986648	c.-196C>G	upstream_gene_variant	1.0	pretomanid
ddn	3986648	c.-196C>G	upstream_gene_variant	1.0	delamanid
ddn	3986655	c.-189A>T	upstream_gene_variant	1.0	pretomanid
ddn	3986655	c.-189A>T	upstream_gene_variant	1.0	delamanid
clpC1	4038248	c.2457C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038260	p.Asp815Glu	missense_variant	0.9	pyrazinamide
clpC1	4038271	p.Pro812Ala	missense_variant	1.0	pyrazinamide
clpC1	4038274	p.Gly811Ser	missense_variant	1.0	pyrazinamide
clpC1	4038275	c.2430A>G	synonymous_variant	0.82	pyrazinamide
clpC1	4038278	c.2427T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038302	c.2403C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4038308	c.2397G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038314	c.2391T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038317	c.2388G>C	synonymous_variant	0.8	pyrazinamide
clpC1	4038320	c.2385G>A	synonymous_variant	1.0	pyrazinamide
clpC1	4038326	c.2379G>A	synonymous_variant	0.84	pyrazinamide
clpC1	4038350	c.2355C>G	synonymous_variant	0.82	pyrazinamide
clpC1	4038356	c.2349T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038359	c.2346A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038368	c.2337T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038388	c.2317T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038392	c.2313C>T	synonymous_variant	0.77	pyrazinamide
clpC1	4038398	c.2307G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038403	c.2302T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038456	p.Val750Glu	missense_variant	1.0	pyrazinamide
clpC1	4038458	c.2247G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038461	c.2244G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038486	p.Gly740Thr	missense_variant	1.0	pyrazinamide
clpC1	4038498	p.Ser736Thr	missense_variant	0.94	pyrazinamide
clpC1	4038530	p.Glu725Asp	missense_variant	0.86	pyrazinamide
clpC1	4038533	p.Arg724Lys	missense_variant	0.83	pyrazinamide
clpC1	4038596	c.2109A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038623	c.2082A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038640	p.Asp689Asn	missense_variant	0.88	pyrazinamide
clpC1	4038653	c.2052C>T	synonymous_variant	0.92	pyrazinamide
clpC1	4038658	p.Lys683Gln	missense_variant	0.9	pyrazinamide
clpC1	4038661	p.Ser682Thr	missense_variant	1.0	pyrazinamide
clpC1	4038662	c.2043T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038671	c.2034T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038683	c.2022T>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038713	c.1992T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038740	c.1965G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038755	c.1950G>T	synonymous_variant	0.71	pyrazinamide
clpC1	4038773	c.1932T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038782	c.1923G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038790	c.1915C>T	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
clpC1	4038812	c.1893T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4038815	c.1890G>C	synonymous_variant	0.85	pyrazinamide
clpC1	4038869	c.1836G>A	synonymous_variant	0.91	pyrazinamide
clpC1	4038890	c.1815G>A	synonymous_variant	1.0	pyrazinamide
clpC1	4038914	c.1791G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038917	c.1788C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038923	c.1780_1782delCTAinsTTG	synonymous_variant	1.0	pyrazinamide
clpC1	4038953	c.1752A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038965	c.1740T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038971	c.1734T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038974	c.1731T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038989	c.1716T>C	synonymous_variant	0.85	pyrazinamide
clpC1	4038997	c.1708T>C	synonymous_variant	0.95	pyrazinamide	Not assoc w R - Interim
clpC1	4039022	c.1683A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4039046	c.1659C>A	synonymous_variant	0.74	pyrazinamide
clpC1	4039064	c.1641C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4039070	c.1635G>A	synonymous_variant	0.79	pyrazinamide
clpC1	4039097	c.1608G>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039103	c.1602T>C	synonymous_variant	0.77	pyrazinamide
clpC1	4039106	c.1599G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039128	p.Lys526Arg	missense_variant	0.67	pyrazinamide
clpC1	4039142	c.1563A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039158	p.Lys516Arg	missense_variant	0.8	pyrazinamide
clpC1	4039169	p.Glu512Asp	missense_variant	1.0	pyrazinamide
clpC1	4039172	c.1533A>G	synonymous_variant	0.91	pyrazinamide
clpC1	4039178	c.1527G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039183	c.1522T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039256	c.1449G>A	synonymous_variant	1.0	pyrazinamide
clpC1	4039442	c.1263A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039454	c.1251A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039463	c.1242C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039469	c.1236T>C	synonymous_variant	0.73	pyrazinamide
clpC1	4039472	c.1233G>C	synonymous_variant	0.73	pyrazinamide
clpC1	4039481	c.1224T>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039484	c.1221T>C	synonymous_variant	0.77	pyrazinamide
clpC1	4039508	c.1197G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039514	c.1191C>T	synonymous_variant	0.79	pyrazinamide
clpC1	4039552	c.1153C>T	synonymous_variant	0.79	pyrazinamide
clpC1	4039553	c.1152C>T	synonymous_variant	0.85	pyrazinamide
clpC1	4039556	c.1149G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039559	c.1146C>G	synonymous_variant	0.85	pyrazinamide
clpC1	4039574	p.Ala377Gly	missense_variant	1.0	pyrazinamide
clpC1	4039577	c.1128T>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4039610	c.1095G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4039613	c.1092C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4039616	c.1089G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039622	c.1083C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4039661	c.1044T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039826	c.879C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4039831	c.874T>C	synonymous_variant	0.86	pyrazinamide
clpC1	4039850	c.855T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039865	c.840T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039913	c.792C>T	synonymous_variant	0.95	pyrazinamide
clpC1	4039931	c.774T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039946	c.759A>T	synonymous_variant	0.96	pyrazinamide
clpC1	4039952	c.753T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039955	c.750G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039958	c.747G>C	synonymous_variant	0.96	pyrazinamide
clpC1	4039979	c.726C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039982	c.723G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039985	c.720G>A	synonymous_variant	1.0	pyrazinamide
clpC1	4039991	c.714G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039996	p.Glu237Gln	missense_variant	1.0	pyrazinamide
clpC1	4040009	c.696C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040021	c.684A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040024	c.681A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040033	c.672G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040042	c.663C>T	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040048	c.657C>T	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
clpC1	4040090	c.613_615delTCTinsAGC	synonymous_variant	1.0	pyrazinamide
clpC1	4040093	c.610_612delCTCinsTTG	synonymous_variant	1.0	pyrazinamide
clpC1	4040105	c.600C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040147	c.558A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040153	c.552A>G	synonymous_variant	0.94	pyrazinamide
clpC1	4040162	c.543G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040165	c.540G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040171	c.534C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040200	c.505T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040201	c.504C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040207	c.498T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040213	c.492T>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040225	c.480A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040228	c.477G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040237	c.468C>A	synonymous_variant	1.0	pyrazinamide
clpC1	4040258	c.447G>A	synonymous_variant	0.93	pyrazinamide
clpC1	4040267	c.438A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040314	c.391C>T	synonymous_variant	0.9	pyrazinamide
clpC1	4040465	c.240T>C	synonymous_variant	0.9	pyrazinamide
clpC1	4040477	c.228G>A	synonymous_variant	0.92	pyrazinamide
clpC1	4040480	c.225T>C	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
clpC1	4040486	c.219G>C	synonymous_variant	0.85	pyrazinamide
clpC1	4040522	c.183T>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4040528	c.177G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4040531	c.174T>C	synonymous_variant	0.82	pyrazinamide
clpC1	4040534	c.171A>G	synonymous_variant	0.91	pyrazinamide	Not assoc w R - Interim
clpC1	4040537	c.168G>C	synonymous_variant	0.82	pyrazinamide
clpC1	4040546	c.159G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040551	c.154T>C	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
panD	4044204	c.78G>C	synonymous_variant	0.7	pyrazinamide
panD	4045028	c.-747C>G	upstream_gene_variant	0.9	pyrazinamide
panD	4045055	c.-774T>G	upstream_gene_variant	0.93	pyrazinamide
panD	4045066	c.-785G>T	upstream_gene_variant	1.0	pyrazinamide
panD	4045067	c.-786C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4045073	c.-792C>T	upstream_gene_variant	1.0	pyrazinamide
panD	4045076	c.-795A>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045085	c.-804G>A	upstream_gene_variant	1.0	pyrazinamide
panD	4045088	c.-807T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045094	c.-813T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045097	c.-816T>C	upstream_gene_variant	1.0	pyrazinamide
glpK	4138606	c.1150T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138607	c.1149G>A	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138615	p.Ile381Val	missense_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138622	c.1134C>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138631	c.1125C>T	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138634	c.1122G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
embC	4239305	c.-558G>C	upstream_gene_variant	0.9	ethambutol
embC	4239329	c.-534C>T	upstream_gene_variant	0.85	ethambutol
embC	4239336	c.-527T>C	upstream_gene_variant	0.92	ethambutol
embC	4239341	c.-522G>A	upstream_gene_variant	0.92	ethambutol
embC	4239344	c.-519G>C	upstream_gene_variant	0.85	ethambutol
embC	4239350	c.-513G>C	upstream_gene_variant	0.85	ethambutol
embC	4239377	c.-486C>T	upstream_gene_variant	0.91	ethambutol
embC	4239378	c.-485T>C	upstream_gene_variant	1.0	ethambutol
embC	4240671	p.Thr270Ile	missense_variant	0.92	ethambutol	Not assoc w R
embC	4240678	c.816T>C	synonymous_variant	0.92	ethambutol
embC	4240685	p.Thr275Ala	missense_variant	0.93	ethambutol
embC	4240693	c.831T>C	synonymous_variant	0.95	ethambutol
embC	4240699	c.837C>G	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embC	4240703	c.841C>T	synonymous_variant	0.86	ethambutol
embC	4240726	c.864G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embC	4240780	c.918T>C	synonymous_variant	0.86	ethambutol
embC	4240783	c.921G>C	synonymous_variant	0.96	ethambutol
embC	4240789	c.927T>C	synonymous_variant	0.96	ethambutol
embC	4240819	c.957A>C	synonymous_variant	0.94	ethambutol
embC	4240822	c.960C>G	synonymous_variant	0.95	ethambutol
embC	4240831	c.969T>G	synonymous_variant	0.95	ethambutol
embC	4240861	c.999G>A	synonymous_variant	0.89	ethambutol	Not assoc w R - Interim
embC	4240867	c.1005T>C	synonymous_variant	0.94	ethambutol
embC	4240879	c.1017G>C	synonymous_variant	1.0	ethambutol
embC	4240880	p.Ala340Thr	missense_variant	1.0	ethambutol	Uncertain significance
embC	4240886	p.Ile342Val	missense_variant	0.92	ethambutol
embC	4240897	c.1035C>G	synonymous_variant	1.0	ethambutol	Not assoc w R
embC	4240898	c.1036_1038delCTAinsTTG	synonymous_variant	0.92	ethambutol
embC	4241017	c.1155T>C	synonymous_variant	1.0	ethambutol
embC	4241023	c.1161T>C	synonymous_variant	1.0	ethambutol
embC	4241050	c.1188T>G	synonymous_variant	1.0	ethambutol
embC	4241053	c.1191G>T	synonymous_variant	1.0	ethambutol
embC	4241065	c.1203C>T	synonymous_variant	0.94	ethambutol
embC	4241071	c.1209C>G	synonymous_variant	0.94	ethambutol
embC	4241104	c.1242G>A	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embC	4241107	c.1245G>C	synonymous_variant	1.0	ethambutol
embC	4241140	c.1278A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embC	4241161	c.1299C>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embC	4241162	c.1300T>C	synonymous_variant	1.0	ethambutol
embC	4241167	c.1305C>G	synonymous_variant	0.93	ethambutol
embC	4241179	c.1317G>A	synonymous_variant	0.92	ethambutol
embC	4241188	c.1326C>A	synonymous_variant	0.92	ethambutol
embC	4241230	c.1368A>G	synonymous_variant	0.91	ethambutol
embA	4245074	c.1842G>C	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
embA	4245078	p.Trp616Val	missense_variant	0.92	ethambutol
embA	4245083	c.1851A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embA	4245089	c.1857G>C	synonymous_variant	0.92	ethambutol
embA	4245093	p.Ile621Val	missense_variant	0.92	ethambutol	Uncertain significance
embA	4245101	c.1869G>C	synonymous_variant	1.0	ethambutol
embA	4245137	c.1905T>C	synonymous_variant	1.0	ethambutol
embA	4245149	c.1917C>G	synonymous_variant	1.0	ethambutol
embA	4245164	c.1932C>T	synonymous_variant	0.82	ethambutol
embA	4245173	c.1941G>C	synonymous_variant	0.82	ethambutol
embA	4245182	c.1950T>C	synonymous_variant	0.9	ethambutol
embA	4245183	c.1951C>T	synonymous_variant	0.8	ethambutol
embA	4245189	c.1957C>T	synonymous_variant	0.8	ethambutol
embA	4245198	p.Leu656Ile	missense_variant	0.67	ethambutol
embB	4247407	c.894G>C	synonymous_variant	1.0	ethambutol
embB	4247437	c.924A>C	synonymous_variant	1.0	ethambutol
embB	4247464	c.951C>G	synonymous_variant	0.96	ethambutol
embB	4247470	c.957T>C	synonymous_variant	1.0	ethambutol
embB	4247491	c.978G>C	synonymous_variant	0.94	ethambutol
embB	4247497	c.984T>C	synonymous_variant	1.0	ethambutol
embB	4247512	c.999T>C	synonymous_variant	1.0	ethambutol
embB	4248226	c.1713G>C	synonymous_variant	0.91	ethambutol
embB	4248277	c.1764G>C	synonymous_variant	0.92	ethambutol
embB	4248280	c.1767C>T	synonymous_variant	0.92	ethambutol
embB	4248307	c.1794G>T	synonymous_variant	0.8	ethambutol
embB	4249339	c.2826T>C	synonymous_variant	1.0	ethambutol
embB	4249342	c.2829C>G	synonymous_variant	1.0	ethambutol
embB	4249343	p.Val944Phe	missense_variant	0.9	ethambutol
embB	4249351	c.2838C>G	synonymous_variant	0.9	ethambutol
aftB	4267595	c.1242C>T	synonymous_variant	0.91	ethambutol
aftB	4267604	c.1233C>T	synonymous_variant	0.91	ethambutol
aftB	4267625	c.1212T>C	synonymous_variant	1.0	ethambutol
aftB	4267631	c.1206C>G	synonymous_variant	0.91	ethambutol
aftB	4267634	p.Arg401His	missense_variant	0.91	ethambutol
aftB	4267649	c.1188T>C	synonymous_variant	0.91	ethambutol	Not assoc w R - Interim
aftB	4267655	c.1182C>G	synonymous_variant	1.0	ethambutol
ubiA	4269177	c.657G>A	synonymous_variant	0.8	ethambutol	Not assoc w R - Interim
aftB	4269183	c.-347T>C	upstream_gene_variant	0.9	ethambutol
aftB	4269201	c.-365A>G	upstream_gene_variant	0.82	ethambutol

TB-Profiler result