TB-Profiler result

Run: SRR1915487
Summary

Run ID: SRR1915487

Sample name:

Date: 2024-04-15T17:28:59.628368

Number of reads: 2078338

Percentage reads mapped: 85.03

Median coverage: 57.0

Strain: La1.2.BCG

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 1.0
La1.2 M.bovis None 0.99
La1 M.bovis None 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide pncA p.His57Asp Assoc w R
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 467 p.His156Arg missense_variant 1.0 isoniazid Not assoc w R
gyrB 5752 c.513G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6406 c.1167C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6446 p.Ala403Ser missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8285 c.984C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8741 c.1440C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13197 p.Thr121Ser missense_variant 1.0 isoniazid Not assoc w R
Rv0010c 13228 c.330delG frameshift_variant 1.0 isoniazid Uncertain significance
Rv0010c 13460 c.99T>C synonymous_variant 0.98 isoniazid Not assoc w R
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
nusG 734451 c.198G>C synonymous_variant 0.14 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.14 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.15 rifampicin
nusG 734499 c.246G>C synonymous_variant 0.14 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 0.15 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.17 rifampicin
rpoB 760337 c.531C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760340 c.534G>C synonymous_variant 0.16 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760407 p.Ser201Gly missense_variant 0.15 rifampicin Uncertain significance
rpoB 760457 c.651C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 0.21 rifampicin
rpoB 760514 c.708C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.21 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 0.19 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.2 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.2 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.21 rifampicin
rpoB 760585 p.Asn260Thr missense_variant 0.19 rifampicin
rpoB 760590 p.Val262Ser missense_variant 0.18 rifampicin
rpoB 760607 c.801G>C synonymous_variant 0.14 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.14 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.35 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.33 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.34 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.21 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.24 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761303 c.1497G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.22 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.18 rifampicin
rpoB 761347 p.Val514Glu missense_variant 0.17 rifampicin
rpoB 761349 p.Asp515Asn missense_variant 0.17 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.17 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.17 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.16 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.17 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.18 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.24 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.25 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.25 rifampicin
rpoB 761657 c.1851C>A synonymous_variant 0.24 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.25 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.25 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.23 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.21 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.18 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.16 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.27 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.26 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.22 rifampicin Uncertain significance
rpoB 762134 c.2328C>T synonymous_variant 0.22 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.2 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.2 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>T synonymous_variant 0.21 rifampicin
rpoB 762218 c.2412T>C synonymous_variant 0.16 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.19 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.18 rifampicin Uncertain significance
rpoB 762810 c.3004_3006delGCCinsTG frameshift_variant&missense_variant 0.26 rifampicin
rpoB 762814 p.Met1003Thr missense_variant 0.27 rifampicin Uncertain significance
rpoB 762818 c.3012C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.3 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.35 rifampicin Uncertain significance
rpoB 762899 c.3093G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.28 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.28 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.24 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.75 rifampicin Not assoc w R
rpoB 763040 c.3234C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763049 c.-321G>A upstream_gene_variant 0.26 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.33 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 0.32 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.2 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 0.24 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.16 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.25 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 0.25 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 0.26 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.25 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.28 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 0.4 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763575 p.Arg69Pro missense_variant 0.58 rifampicin Not assoc w R
rpoC 763594 c.225C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.4 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>T synonymous_variant 0.36 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.39 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.39 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763741 c.372C>T synonymous_variant 0.27 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.26 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.19 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.21 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763858 c.489A>G synonymous_variant 0.15 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.15 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.15 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.15 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.15 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.15 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.17 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.17 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.19 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.18 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.18 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763967 p.Gly200Ser missense_variant 0.18 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.15 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.15 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.14 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.14 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.19 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.19 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.2 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.21 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.24 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.29 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.32 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.3 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.32 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.3 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764296 c.927G>C synonymous_variant 0.26 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.26 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.29 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.31 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 0.26 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.24 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.32 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.32 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.32 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.29 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.33 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.35 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.33 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>C synonymous_variant 0.31 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.33 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.42 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.39 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.39 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.3 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCT frameshift_variant&synonymous_variant 0.25 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.25 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.25 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.25 rifampicin Uncertain significance
rpoC 764920 c.1551G>C synonymous_variant 0.25 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.26 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765338 p.Gln657Lys missense_variant 0.16 rifampicin
rpoC 765357 p.Met663Thr missense_variant 0.15 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.15 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.15 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.16 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.15 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.15 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.16 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.17 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.16 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.15 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.16 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.16 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.17 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.17 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.17 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.17 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766911 p.Ile1181Thr missense_variant 0.14 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.14 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 0.15 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.14 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.16 rifampicin
rpoC 766951 c.3582G>C synonymous_variant 0.18 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767163 p.Asn1265Ser missense_variant 0.36 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.31 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781568 c.9C>T synonymous_variant 0.87 streptomycin Not assoc w R
rpsL 781608 p.Ser17Ala missense_variant 0.16 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.14 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.15 streptomycin Not assoc w R - Interim
rpsL 781652 c.93T>C synonymous_variant 0.18 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.2 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.19 streptomycin
rpsL 781664 c.105C>G synonymous_variant 0.18 streptomycin
rpsL 781670 c.111G>T synonymous_variant 0.18 streptomycin Not assoc w R - Interim
rpsL 781706 c.147T>C synonymous_variant 0.16 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.15 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.15 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.15 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.17 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.16 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.14 streptomycin
rpsL 781781 c.222G>T synonymous_variant 0.22 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.26 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.28 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.3 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.28 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.25 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.29 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.29 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.3 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.3 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.31 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.3 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.31 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.3 streptomycin
rpsL 781910 c.351C>T synonymous_variant 0.29 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.29 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.27 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.28 streptomycin
rplC 800654 c.-155T>C upstream_gene_variant 0.15 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.15 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
Rv1129c 1254582 c.-48A>G upstream_gene_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
sigE 1364961 c.549A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.15 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 0.16 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.17 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472290 n.445C>A non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>T non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472518 n.673G>C non_coding_transcript_exon_variant 0.14 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.34 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472544 n.699C>G non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472553 n.708C>T non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472572 n.727T>C non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
rrs 1472574 n.729T>C non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472582 n.738_739delTA non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472594 n.749G>C non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472678 n.833_834delTTinsGCC non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472684 n.839_845delGGGATCCinsA non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 0.14 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>C non_coding_transcript_exon_variant 0.14 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.16 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472836 n.991G>C non_coding_transcript_exon_variant 0.15 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473094 n.1249T>A non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>C non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473127 n.1282G>T non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473131 n.1286G>T non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473147 n.1302G>C non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473172 n.1327T>C non_coding_transcript_exon_variant 0.21 streptomycin Not assoc w R
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.21 streptomycin Not assoc w R
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473201 n.1356_1357delACinsT non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.22 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1474095 n.438A>G non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474104 n.448_452delTATCA non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474285 n.630_637delTCCTTTTC non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474298 n.641T>G non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474299 n.642C>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474302 n.645_646delGAinsTGTCGT non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474305 n.649_653delAGGGT non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474420 n.764_769delGCGCAT non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1474428 n.771C>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTCCAAG non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.21 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.21 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474797 n.1140_1141insTATA non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474800 n.1144_1147delGTGC non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474955 n.1298T>G non_coding_transcript_exon_variant 0.15 capreomycin
linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1475017 n.1360_1361insA non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475202 n.1545G>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1475343 n.1686A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475358 n.1701T>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475378 n.1721A>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1475387 n.1730C>T non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475398 n.1741C>G non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475399 n.1742T>G non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475762 n.2105G>C non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475764 n.2107_2108delAAinsTTTGG non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.45 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.31 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.3 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.31 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.31 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.75 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.61 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.19 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rpsA 1833547 c.6G>A synonymous_variant 0.27 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.32 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.4 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.4 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.39 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.45 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.45 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.45 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.45 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.5 pyrazinamide
rpsA 1833658 c.117C>G synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
rpsA 1833664 c.123C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.58 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.58 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.56 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.56 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.55 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.56 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.56 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.57 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.59 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 0.66 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.64 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.63 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.63 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.66 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.63 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.62 pyrazinamide
rpsA 1833838 c.297G>A synonymous_variant 0.59 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.59 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.58 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.61 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.59 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.55 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.55 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 0.59 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.62 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.63 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.64 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.67 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.58 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.57 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.58 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.57 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.59 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 0.61 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.57 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.63 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.64 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.63 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.58 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.56 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.51 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.52 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.5 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.45 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.38 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.39 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.37 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.36 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.45 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.45 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.51 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.47 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.5 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.49 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.48 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.46 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.43 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.43 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.41 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.42 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 0.34 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834859 p.Ala440Thr missense_variant 0.96 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2062922 p.Ile603Val missense_variant 1.0 streptomycin Not assoc w R
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
ndh 2102106 p.Gly313Arg missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Not assoc w R - Interim
ndh 2103173 c.-132delG upstream_gene_variant 1.0 ethionamide
delamanid
isoniazid
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155503 c.609C>T synonymous_variant 1.0 isoniazid Not assoc w R
katG 2156025 c.87C>A synonymous_variant 1.0 isoniazid Not assoc w R
katG 2156465 c.-354C>T upstream_gene_variant 1.0 isoniazid Not assoc w R - Interim
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
PPE35 2168011 p.Ser868Arg missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168814 c.1798dupA frameshift_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168920 p.Val565Phe missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2221058 c.-8682_*660del transcript_ablation 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
kasA 2517941 c.-174C>G upstream_gene_variant 0.31 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.3 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.29 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.28 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.26 isoniazid
kasA 2517980 c.-135C>G upstream_gene_variant 0.24 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 0.22 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 0.22 isoniazid
kasA 2517992 c.-123C>T upstream_gene_variant 0.22 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.21 isoniazid
kasA 2518633 c.519G>C synonymous_variant 0.22 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.24 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.32 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.31 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.3 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.3 isoniazid
kasA 2518687 c.573C>T synonymous_variant 0.32 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.31 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.33 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.31 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.31 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.31 isoniazid
kasA 2518727 c.613C>T synonymous_variant 0.42 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.43 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.41 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.27 isoniazid
kasA 2518763 c.649_651delTCGinsAGC synonymous_variant 0.25 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.24 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.25 isoniazid
kasA 2518783 c.669T>G synonymous_variant 0.23 isoniazid
kasA 2518784 p.Glu224Gln missense_variant 0.23 isoniazid
kasA 2518787 c.673_675delCGGinsGC frameshift_variant&missense_variant 0.21 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.21 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.21 isoniazid
kasA 2518798 c.684G>T synonymous_variant 0.21 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.2 isoniazid
Rv2477c 2782928 p.Thr372Lys missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Not assoc w R
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Not assoc w R
amikacin Uncertain significance
Rv2681 2997325 p.Ala196Val missense_variant 1.0 capreomycin Uncertain significance
ald 3086728 c.-92C>T upstream_gene_variant 1.0 cycloserine
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087084 c.266delA frameshift_variant 1.0 cycloserine
Rv3083 3448745 p.Ile81Ser missense_variant 1.0 ethionamide Uncertain significance
Rv3083 3448783 p.Val94Ile missense_variant 1.0 ethionamide Uncertain significance
lpqB 3623730 p.Ser394Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624350 c.561G>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624486 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624593 c.318G>A synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624710 c.201G>A synonymous_variant 0.94 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
rpoA 3877638 c.870T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.17 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.18 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.18 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.19 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.16 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.14 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3878630 c.-124delC upstream_gene_variant 1.0 rifampicin Not assoc w R
rpoA 3878938 c.-431T>G upstream_gene_variant 0.17 rifampicin
rpoA 3878944 c.-437G>C upstream_gene_variant 0.15 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 0.15 rifampicin
rpoA 3878950 c.-443C>G upstream_gene_variant 0.15 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 0.2 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 0.2 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 0.2 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.19 rifampicin
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.21 rifampicin
rpoA 3879013 c.-508_-506delGAAinsAC upstream_gene_variant 0.22 rifampicin
rpoA 3879016 c.-509A>C upstream_gene_variant 0.25 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.29 rifampicin
rpoA 3879040 c.-535_-533delGTGinsAAC upstream_gene_variant 0.26 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.4 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.4 rifampicin
rpoA 3879088 c.-582_-581delCAinsGC upstream_gene_variant 0.4 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.42 rifampicin
rpoA 3879121 c.-615_-614delTTinsAG upstream_gene_variant 0.39 rifampicin
rpoA 3879124 c.-618_-617delTGinsGT upstream_gene_variant 0.4 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.4 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.42 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.46 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.45 rifampicin
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038474 p.Ser744Thr missense_variant 0.18 pyrazinamide
clpC1 4038486 p.Gly740Asp missense_variant 0.16 pyrazinamide
clpC1 4038491 c.2214C>G synonymous_variant 0.14 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.16 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 0.16 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.17 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.23 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.22 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.24 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.3 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.27 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.34 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.34 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>T synonymous_variant 0.46 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.47 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.46 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.43 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.45 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.44 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.44 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.45 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.47 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.49 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.41 pyrazinamide
clpC1 4039007 c.1698G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.42 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.16 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.16 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.16 pyrazinamide
clpC1 4039199 c.1506C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039238 c.1467C>G synonymous_variant 0.17 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4039466 c.1239T>C synonymous_variant 0.24 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.19 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039574 c.1129_1131delGCGinsTC frameshift_variant&missense_variant 0.16 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039610 c.1095G>T synonymous_variant 0.24 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.3 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.34 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.3 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.3 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.32 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.34 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.22 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.22 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.17 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.17 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.16 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.14 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.14 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.14 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.14 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.35 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.44 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.44 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.42 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.26 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040393 c.312G>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040417 c.288G>C synonymous_variant 0.18 pyrazinamide
clpC1 4040426 c.279T>C synonymous_variant 0.18 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>T synonymous_variant 0.17 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.17 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.15 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.15 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.15 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
glpK 4138377 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
embC 4242029 c.2167C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242970 c.3108C>T synonymous_variant 0.97 ethambutol Not assoc w R
embA 4244220 c.988C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4246551 p.Asn13Ser missense_variant 1.0 ethambutol Not assoc w R
embB 4246864 c.351C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247173 c.660G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
aftB 4267858 p.Ile327Val missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269351 c.483C>T synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269689 p.Val49Ile missense_variant 1.0 ethambutol Not assoc w R - Interim
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R