TB-Profiler result

Run: SRR29093105
Summary

Run ID: SRR29093105

Sample name:

Date: 2025-02-11T14:03:01.878104

Number of reads: 357823

Percentage reads mapped: 54.48

Median coverage: 7.0

Strain: lineage2.2.2;lineage4

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.21
lineage2.2.2 East-Asian (Beijing) RD105;RD207 0.33
lineage2.2 East-Asian (Beijing) RD105;RD207 0.49
lineage4 Euro-American None 0.72
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
p.Ala659Thr Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.9 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.94 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.72 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.79 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.75 ethambutol Mutation from literature
embB 4248488 p.Ala659Thr missense_variant 0.67 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 876 c.876C>G synonymous_variant 0.73 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.68 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.71 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.65 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.59 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.59 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.56 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.53 isoniazid Not assoc w R - Interim
dnaA 1008 c.1008G>A synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 1137 c.1137C>G synonymous_variant 0.67 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.67 isoniazid
gyrB 6123 p.Ala295Gly missense_variant 0.64 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.88 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.82 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8387 c.1086C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 p.Tyr364His missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318_1320delTTGinsCTA synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Ser missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8837 c.1536C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.85 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.84 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.91 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13852 c.-296_-294delTTAinsCTG upstream_gene_variant 0.8 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 0.8 isoniazid
Rv0010c 13864 c.-306A>G upstream_gene_variant 0.8 isoniazid
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.8 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.86 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.86 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.86 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.86 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.86 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.86 isoniazid
mshA 574616 c.-732G>C upstream_gene_variant 0.58 isoniazid
ethionamide
mshA 574619 c.-729C>G upstream_gene_variant 0.58 isoniazid
ethionamide
mshA 574640 c.-708G>A upstream_gene_variant 0.73 isoniazid
ethionamide
mshA 574650 c.-698A>C upstream_gene_variant 0.82 isoniazid
ethionamide
mshA 574655 c.-693C>G upstream_gene_variant 0.82 isoniazid
ethionamide
mshA 574664 c.-684G>C upstream_gene_variant 0.82 isoniazid
ethionamide
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.75 isoniazid
ethionamide
mshA 574676 c.-672G>C upstream_gene_variant 0.75 isoniazid
ethionamide
mshA 574683 c.-665T>C upstream_gene_variant 0.75 isoniazid Uncertain significance
ethionamide
mshA 574688 c.-660G>C upstream_gene_variant 0.75 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.75 isoniazid
ethionamide
mshA 574712 c.-636A>G upstream_gene_variant 0.82 isoniazid
ethionamide
mshA 574718 c.-630A>G upstream_gene_variant 0.82 isoniazid
ethionamide
mshA 574724 c.-624T>C upstream_gene_variant 0.9 isoniazid
ethionamide
mshA 574731 c.-617A>G upstream_gene_variant 0.9 isoniazid
ethionamide
mshA 574739 c.-609T>C upstream_gene_variant 0.9 isoniazid
ethionamide
ccsA 620226 c.336G>A synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.61 kanamycin
capreomycin
amikacin
ccsA 620265 c.375C>G synonymous_variant 0.62 kanamycin
capreomycin
amikacin
ccsA 620268 c.378G>C synonymous_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.66 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620298 c.408G>C synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.78 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.79 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.77 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.77 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.74 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.74 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.9 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620424 c.534G>C synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 0.79 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.79 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>G synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620481 c.591T>G synonymous_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620482 p.Val198Leu missense_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620490 c.600A>C synonymous_variant 0.43 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620569 p.Gly227Arg missense_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620583 c.693G>C synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620586 c.696C>G synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 620601 c.711C>T synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>C synonymous_variant 0.74 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>G synonymous_variant 0.77 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>G synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620646 c.756G>A synonymous_variant 0.96 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620659 c.769_771delCGCinsAGG synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620664 c.774C>T synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620682 c.792G>A synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620688 c.798G>C synonymous_variant 0.98 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620763 c.873G>A synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620769 c.879C>G synonymous_variant 0.9 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620784 c.894C>G synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620790 c.900C>T synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620809 c.919C>T synonymous_variant 0.84 kanamycin
capreomycin
amikacin
ccsA 620823 c.933C>T synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620832 c.942C>T synonymous_variant 0.69 kanamycin
capreomycin
amikacin
Rv0565c 657318 c.153T>C synonymous_variant 0.7 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.7 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.7 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.64 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.64 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.64 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.64 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.64 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.69 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.74 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.83 ethionamide
hadA 731717 c.-213T>G upstream_gene_variant 0.81 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.82 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.81 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.75 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.62 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.58 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.58 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.58 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.54 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.54 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.54 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.55 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.76 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.79 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.79 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.79 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.83 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.83 isoniazid
nusG 734442 c.189G>A synonymous_variant 0.92 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.93 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.93 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.89 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.88 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.83 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.83 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.86 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.86 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.83 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.83 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.95 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.88 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.94 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.98 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.98 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.98 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.98 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.96 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.97 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.94 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.9 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.93 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.92 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.88 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.88 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.81 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.81 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.74 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.72 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.72 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.72 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.71 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.74 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.77 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.71 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.65 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.6 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.64 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.73 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.85 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.91 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.91 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.91 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.91 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.89 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.88 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.88 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.87 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.86 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.93 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.9 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.94 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.94 rifampicin
rpoB 761373 p.Val523His missense_variant 0.93 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.95 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.91 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.9 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.9 rifampicin
rpoB 761439 p.Asp545Lys missense_variant 0.9 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.89 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.93 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.9 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.93 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.97 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.97 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.95 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.96 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.96 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.96 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.95 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.96 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 0.96 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.96 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.96 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.97 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.97 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.95 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.95 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.93 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.93 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.93 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.91 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.86 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.87 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.9 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.91 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.84 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.85 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.85 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.85 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.85 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.81 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.88 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.93 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.93 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.93 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.96 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.98 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.98 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.98 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.98 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.95 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.95 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.95 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.95 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.94 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.94 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.94 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.94 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.93 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.9 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.93 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.96 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.96 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.96 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.96 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.95 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.95 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.95 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.95 rifampicin
rpoB 762860 c.3054G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.81 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.82 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.86 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.87 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.84 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.86 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.86 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.86 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.86 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.87 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.86 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.82 rifampicin
rpoC 763402 c.33C>G synonymous_variant 0.85 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.88 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.9 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.93 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.89 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.9 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.9 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.88 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.87 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.84 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.84 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.85 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.82 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.82 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.8 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.8 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.8 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.8 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.82 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.82 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.82 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.77 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.81 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.81 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.79 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.77 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.82 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.8 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.79 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.8 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.77 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.77 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.78 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.83 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.83 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.82 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.82 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.86 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.9 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.89 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.87 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.89 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.9 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.81 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764392 c.1023C>T synonymous_variant 0.83 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.76 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.68 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.68 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.68 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.81 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.8 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.84 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.85 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.85 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.89 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.89 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.89 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.97 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.94 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.88 rifampicin Not assoc w R
rpoC 765421 c.2052C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.76 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.76 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.74 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.74 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.65 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.9 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.91 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.91 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.93 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.9 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.9 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.89 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.9 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.88 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.88 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 0.79 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.84 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.85 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.86 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.87 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.88 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.88 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.88 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.91 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.91 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.94 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.97 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.97 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.92 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.92 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.93 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.94 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.95 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.95 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.96 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.96 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.93 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.93 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.93 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.94 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.94 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.93 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.97 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.95 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.95 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.95 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.96 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.96 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.94 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.96 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.97 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.96 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.98 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.92 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.95 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.94 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.97 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.96 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.95 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpsL 781571 c.12C>T synonymous_variant 0.85 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.92 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.92 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.92 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.95 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.94 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.94 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.95 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.93 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.94 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.94 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.93 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.93 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.92 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.92 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.92 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.92 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.92 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.93 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.93 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.93 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.92 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.91 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.93 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.93 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.95 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.93 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.91 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.93 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.92 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.91 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.85 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.88 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.88 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.89 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.91 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.93 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.91 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.9 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.91 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.91 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.9 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.88 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.88 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.89 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.89 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.89 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.89 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.93 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.9 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.9 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.9 linezolid
rplC 800814 c.6A>G synonymous_variant 0.86 linezolid
rplC 800817 c.9A>T synonymous_variant 0.85 linezolid
rplC 800844 c.36T>C synonymous_variant 0.93 linezolid
rplC 800865 c.57A>G synonymous_variant 0.92 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.91 linezolid
rplC 800874 c.66A>G synonymous_variant 0.9 linezolid
rplC 800875 p.Val23Ile missense_variant 0.9 linezolid
rplC 800880 c.72A>G synonymous_variant 0.95 linezolid
rplC 800889 c.81C>G synonymous_variant 0.95 linezolid
rplC 800892 c.84G>C synonymous_variant 0.95 linezolid
rplC 800907 c.99C>G synonymous_variant 0.95 linezolid
rplC 800916 c.108A>G synonymous_variant 0.95 linezolid
rplC 800934 c.126C>G synonymous_variant 0.9 linezolid
rplC 800937 c.129A>G synonymous_variant 0.89 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.89 linezolid
rplC 800946 c.138T>C synonymous_variant 0.89 linezolid
rplC 800949 c.141T>C synonymous_variant 0.89 linezolid
rplC 800967 c.159C>G synonymous_variant 0.92 linezolid
rplC 800970 c.162T>C synonymous_variant 0.92 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.9 linezolid
rplC 801246 c.438C>T synonymous_variant 0.75 linezolid
rplC 801249 c.441T>C synonymous_variant 0.75 linezolid
rplC 801255 c.447C>T synonymous_variant 0.75 linezolid
rplC 801264 c.456C>T synonymous_variant 0.75 linezolid
rplC 801267 c.459A>T synonymous_variant 0.75 linezolid
rplC 801270 c.462T>C synonymous_variant 0.69 linezolid
rplC 801276 c.468G>C synonymous_variant 0.69 linezolid
rplC 801279 c.471G>C synonymous_variant 0.69 linezolid
rplC 801282 c.474G>C synonymous_variant 0.69 linezolid
rplC 801285 c.477G>C synonymous_variant 0.67 linezolid
rplC 801300 c.492C>G synonymous_variant 0.75 linezolid
rplC 801309 c.501C>G synonymous_variant 0.79 linezolid
rplC 801312 c.504G>C synonymous_variant 0.75 linezolid
rplC 801321 c.513C>T synonymous_variant 0.77 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.77 linezolid
rplC 801339 c.531T>C synonymous_variant 0.77 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.77 linezolid
rplC 801348 c.540T>G synonymous_variant 0.77 linezolid
rplC 801357 c.549T>C synonymous_variant 0.8 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.75 linezolid
rplC 801402 c.594T>C synonymous_variant 0.71 linezolid
rplC 801405 c.597T>C synonymous_variant 0.71 linezolid
rplC 801423 c.615G>C synonymous_variant 0.75 linezolid
rplC 801426 c.618C>G synonymous_variant 0.75 linezolid
rplC 801427 p.Met207Val missense_variant 0.74 linezolid
rplC 801438 c.630T>C synonymous_variant 0.83 linezolid
rplC 801442 p.Ile212Val missense_variant 0.79 linezolid
fbiC 1303761 c.831T>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303797 c.867A>G synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304034 c.1104A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304040 c.1110C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304046 c.1116C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304050 c.1120T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304058 c.1128G>A synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304059 c.1129C>T synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304085 c.1155C>T synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304091 p.Asp387Glu missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304097 c.1167G>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1304132 p.Ala401Gly missense_variant 0.85 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>C synonymous_variant 0.85 pretomanid
delamanid
clofazimine
fbiC 1304511 c.1581C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304535 c.1605G>A synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304545 p.Val539Thr missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
sigE 1364814 c.402C>G synonymous_variant 0.8 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.9 pyrazinamide
sigE 1364839 c.427_429delTTGinsCTC synonymous_variant 0.9 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.9 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.75 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.69 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.64 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.64 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.69 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.67 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.62 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.58 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.58 pyrazinamide
atpE 1461097 p.Ala18Gly missense_variant 0.73 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.73 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.76 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 0.76 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.74 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.74 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 0.74 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.77 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.77 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.77 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.81 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.81 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.79 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.75 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.73 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.92 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
inhA 1673955 c.-247G>C upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.53 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 0.68 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1674015 c.-187C>T upstream_gene_variant 0.75 isoniazid Uncertain significance
ethionamide
inhA 1674018 c.-184G>C upstream_gene_variant 0.72 isoniazid
ethionamide
inhA 1674021 c.-181G>C upstream_gene_variant 0.72 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.8 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1674037 c.-165_-164delCAinsGC upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1674042 c.-160G>T upstream_gene_variant 0.77 isoniazid
ethionamide
inhA 1674049 c.-153_-151delCAAinsGAC upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 0.84 isoniazid
ethionamide
inhA 1674063 c.-139G>C upstream_gene_variant 0.84 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 0.88 isoniazid
ethionamide
inhA 1674114 c.-88T>A upstream_gene_variant 0.77 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.7 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.75 isoniazid
ethionamide
inhA 1674504 c.303C>G synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.88 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.92 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674552 c.351C>G synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.91 isoniazid
ethionamide
inhA 1674601 p.Leu134Thr missense_variant 0.91 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674630 c.429C>G synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674672 c.471C>G synonymous_variant 0.89 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.89 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.89 isoniazid
ethionamide
inhA 1674723 c.522C>T synonymous_variant 0.89 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674738 c.537C>G synonymous_variant 0.85 isoniazid
ethionamide
inhA 1674741 c.540C>T synonymous_variant 0.85 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674746 p.Tyr182Phe missense_variant 0.81 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674753 c.552G>C synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.78 isoniazid
ethionamide
rpsA 1833554 p.Thr5Ala missense_variant 0.82 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.88 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.88 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.88 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.9 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.88 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.8 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.81 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.84 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.84 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.82 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.78 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.67 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.72 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.68 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.77 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.65 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.53 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.75 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.85 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.82 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.82 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.76 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.74 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.72 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.69 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.67 pyrazinamide
bacA 2064870 c.-142A>G upstream_gene_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064873 c.-145A>T upstream_gene_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064882 c.-154C>G upstream_gene_variant 0.71 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064892 c.-164A>G upstream_gene_variant 0.79 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064897 c.-169C>G upstream_gene_variant 0.79 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064903 c.-175G>A upstream_gene_variant 0.76 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064912 c.-184A>G upstream_gene_variant 0.78 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064915 c.-187G>C upstream_gene_variant 0.78 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064933 c.-205A>G upstream_gene_variant 0.84 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.84 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 0.86 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.88 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.97 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.94 kanamycin
capreomycin
streptomycin
amikacin
kasA 2517950 c.-165C>G upstream_gene_variant 0.94 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.87 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.86 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.83 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.8 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.75 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.82 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.82 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.82 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.82 isoniazid
kasA 2518053 c.-62_-60delATTinsCTG upstream_gene_variant 0.8 isoniazid
kasA 2518059 c.-56_-54delTCGinsACC upstream_gene_variant 0.8 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.82 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.93 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.92 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.82 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.71 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.73 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.84 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.84 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.84 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.79 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.79 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.79 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.78 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.78 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.78 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.85 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.86 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.87 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.87 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.87 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.87 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.87 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.93 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.93 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.93 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.93 isoniazid
kasA 2518951 c.837G>C synonymous_variant 0.94 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.93 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.94 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.94 isoniazid
kasA 2518975 c.861C>G synonymous_variant 0.93 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.93 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.92 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.91 isoniazid
kasA 2518999 c.885G>C synonymous_variant 0.88 isoniazid
kasA 2519008 c.894C>G synonymous_variant 0.86 isoniazid
kasA 2519017 c.903G>C synonymous_variant 0.78 isoniazid
kasA 2519020 c.906G>C synonymous_variant 0.82 isoniazid
kasA 2519021 p.Ala303Lys missense_variant 0.82 isoniazid
kasA 2519027 p.Ile305Val missense_variant 0.82 isoniazid
kasA 2519050 c.936C>G synonymous_variant 0.79 isoniazid
kasA 2519053 c.939G>C synonymous_variant 0.8 isoniazid
kasA 2519056 c.942G>C synonymous_variant 0.8 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.79 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.67 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.64 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.55 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.64 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.64 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.67 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 0.7 isoniazid
folC 2746438 c.1161G>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.71 para-aminosalicylic_acid
folC 2746471 c.1128C>A synonymous_variant 0.75 para-aminosalicylic_acid
folC 2746478 p.Phe374Tyr missense_variant 0.75 para-aminosalicylic_acid
folC 2746480 c.1119A>C synonymous_variant 0.75 para-aminosalicylic_acid
folC 2746492 c.1107G>A synonymous_variant 0.67 para-aminosalicylic_acid
folC 2746495 p.His368Gly missense_variant 0.67 para-aminosalicylic_acid
folC 2746507 c.1092A>G synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746510 c.1089A>G synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 0.74 para-aminosalicylic_acid
folC 2746522 c.1077G>C synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746525 c.1074G>T synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746531 c.1068G>C synonymous_variant 0.78 para-aminosalicylic_acid
folC 2746534 c.1065T>C synonymous_variant 0.78 para-aminosalicylic_acid
folC 2746558 c.1041G>T synonymous_variant 0.78 para-aminosalicylic_acid
folC 2746564 c.1035A>G synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746576 c.1023C>G synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747021 p.Val193Ala missense_variant 0.69 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.73 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747248 c.351G>C synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747264 p.Gly112Ala missense_variant 0.78 para-aminosalicylic_acid
folC 2747266 c.333C>T synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.79 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.83 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.83 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.68 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.69 para-aminosalicylic_acid
folC 2747410 c.187_188delAG frameshift_variant 0.73 para-aminosalicylic_acid
folC 2747415 c.184delCinsTTG frameshift_variant&missense_variant 0.73 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747422 c.177G>A synonymous_variant 0.61 para-aminosalicylic_acid
folC 2747425 c.174C>T synonymous_variant 0.61 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.58 para-aminosalicylic_acid
Rv2477c 2783140 c.903C>G synonymous_variant 0.89 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.89 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.9 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.85 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.81 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.72 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783497 c.544_546delTTGinsCTC synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.73 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.69 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.94 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2681 2996278 c.-461T>C upstream_gene_variant 0.7 capreomycin
Rv2681 2996287 c.-452A>C upstream_gene_variant 0.7 capreomycin
Rv2680 2996294 p.Ile64Val missense_variant 0.73 capreomycin
Rv2680 2996308 p.Glu68Asp missense_variant 0.8 capreomycin
Rv2681 2996320 c.-419T>C upstream_gene_variant 0.8 capreomycin
Rv2681 2996323 c.-416G>C upstream_gene_variant 0.8 capreomycin
Rv2681 2996326 c.-413G>A upstream_gene_variant 0.8 capreomycin
Rv2681 2996329 c.-410T>G upstream_gene_variant 0.8 capreomycin
Rv2680 2996335 p.Glu77Asp missense_variant 0.83 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.85 capreomycin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.81 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.81 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.78 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.78 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
fbiB 3642566 c.1032A>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiB 3642581 c.1047A>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiB 3642587 p.Met351Ile missense_variant 0.77 pretomanid
delamanid
clofazimine
fbiB 3642593 c.1059G>T synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiB 3642602 c.1068A>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiB 3642605 c.1071A>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiB 3642609 c.1075_1076delAGinsTC synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiB 3642614 c.1080C>T synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiB 3642617 c.1083C>G synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiB 3642620 c.1086T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiB 3642656 c.1122G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiB 3642659 c.1125C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiB 3642668 c.1134A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiB 3642677 c.1143A>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiB 3642680 c.1146A>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiB 3642684 c.1150T>C synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiB 3642701 c.1167C>G synonymous_variant 0.82 pretomanid
delamanid
clofazimine
rpoA 3877553 p.Glu319Gln missense_variant 0.85 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.84 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.91 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.93 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.91 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.93 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.96 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.98 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.98 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 1.0 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 1.0 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 1.0 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.98 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.96 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.92 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.89 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.89 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.85 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.85 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.86 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.86 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.85 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.83 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.83 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.86 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878094 c.414C>G synonymous_variant 0.85 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.85 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.84 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.85 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.85 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.87 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.86 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.85 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.87 rifampicin
rpoA 3878181 c.327C>T synonymous_variant 0.93 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.93 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.93 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.93 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.92 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.9 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.88 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.86 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.86 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.84 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.81 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.82 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.82 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.83 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.85 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.85 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.83 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.81 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.83 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.83 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.83 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.78 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.74 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.73 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.88 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.88 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.89 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.91 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.91 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.92 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.92 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.92 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.96 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.96 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.97 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.98 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.98 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.98 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.98 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.98 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.98 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.96 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.94 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.94 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.94 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.94 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.96 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.95 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.94 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.96 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.95 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.95 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.94 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.96 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.96 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.95 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.95 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.94 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.97 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 1.0 rifampicin
clpC1 4038596 c.2109A>G synonymous_variant 0.83 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.88 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.93 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.93 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.93 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.98 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.96 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.95 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.78 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.58 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.61 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.58 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.62 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.71 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.72 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.72 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.83 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.83 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.75 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.88 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.89 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.78 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.78 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.84 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.83 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.83 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.83 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.8 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.68 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.65 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.71 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.73 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.71 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.7 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.69 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.69 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.7 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.66 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.71 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.73 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.74 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.79 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.76 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.76 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 0.88 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.88 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.81 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.71 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.69 pyrazinamide
clpC1 4040596 c.109C>T synonymous_variant 0.64 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.69 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.69 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.64 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.64 pyrazinamide
panD 4044084 c.198T>C synonymous_variant 0.92 pyrazinamide
panD 4044105 c.177G>C synonymous_variant 0.93 pyrazinamide
panD 4044117 c.165G>C synonymous_variant 0.93 pyrazinamide
panD 4044120 c.162A>C synonymous_variant 0.93 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.93 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.93 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.94 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.93 pyrazinamide
panD 4044174 c.108C>G synonymous_variant 0.93 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
panD 4044188 c.94T>C synonymous_variant 0.93 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.93 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.93 pyrazinamide
panD 4044213 c.69C>G synonymous_variant 0.91 pyrazinamide
embC 4240693 c.831T>G synonymous_variant 0.7 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.84 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.84 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.87 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.89 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.88 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.88 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.89 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.89 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.89 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.89 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.89 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.89 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.88 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTTG synonymous_variant 0.88 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.88 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.88 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.92 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.92 ethambutol
embA 4245248 c.2016G>C synonymous_variant 0.58 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.54 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.57 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.57 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.67 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.67 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.67 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.73 ethambutol
embA 4245470 c.2238T>C synonymous_variant 0.71 ethambutol
embA 4245473 c.2241C>G synonymous_variant 0.71 ethambutol
embA 4245483 p.Gln751Ala missense_variant 0.75 ethambutol
embA 4245490 p.Val753Ala missense_variant 0.75 ethambutol
embA 4245501 p.Ala757Thr missense_variant 0.75 ethambutol
embA 4245509 c.2277A>G synonymous_variant 0.75 ethambutol
embA 4245512 c.2280G>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4245518 c.-996A>G upstream_gene_variant 0.8 ethambutol
embA 4245524 c.2292G>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4245527 c.-987C>G upstream_gene_variant 0.8 ethambutol
embB 4245530 c.-984T>C upstream_gene_variant 0.86 ethambutol
embA 4245531 p.Ile767Val missense_variant 0.86 ethambutol
embA 4245535 p.Ser768Asn missense_variant 0.86 ethambutol
embB 4245539 c.-975C>G upstream_gene_variant 0.86 ethambutol
embB 4245542 c.-972C>G upstream_gene_variant 0.86 ethambutol
embB 4245557 c.-957G>A upstream_gene_variant 0.84 ethambutol
embB 4245575 c.-939C>G upstream_gene_variant 0.81 ethambutol
embA 4245576 p.Lys782Gln missense_variant 0.81 ethambutol
embA 4245623 c.2391G>C synonymous_variant 0.62 ethambutol Not assoc w R - Interim
embB 4245659 c.-855C>G upstream_gene_variant 0.65 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.59 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.53 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.53 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.53 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.64 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.64 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.72 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.74 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.77 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.74 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.76 ethambutol
embB 4245812 c.-702G>C upstream_gene_variant 0.75 ethambutol
embA 4245813 p.Pro861Ala missense_variant 0.75 ethambutol
embA 4245820 p.Ser863Thr missense_variant 0.77 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.77 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.8 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.77 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.77 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.77 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.73 ethambutol
embA 4245885 p.Asp885Thr missense_variant 0.43 ethambutol
embA 4245892 p.Ile887Thr missense_variant 0.47 ethambutol Uncertain significance
embA 4245899 c.2667C>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4245902 c.-612G>A upstream_gene_variant 0.54 ethambutol
embB 4245905 c.-609C>G upstream_gene_variant 0.5 ethambutol
embB 4245911 c.-603A>G upstream_gene_variant 0.5 ethambutol
embB 4245917 c.-597G>A upstream_gene_variant 0.5 ethambutol
embA 4246055 c.2823T>C synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embB 4246064 c.-450T>C upstream_gene_variant 0.64 ethambutol
embA 4246080 p.Pro950Ser missense_variant 0.67 ethambutol
embA 4246088 c.2856A>G synonymous_variant 0.73 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.75 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.77 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.76 ethambutol
embA 4246128 p.Ser966Thr missense_variant 0.71 ethambutol
embA 4246138 p.Arg969Gln missense_variant 0.73 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 0.7 ethambutol
embA 4246143 p.Ile971Val missense_variant 0.7 ethambutol
embA 4246151 c.2919A>G synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embA 4246152 p.Ala974Gln missense_variant 0.73 ethambutol
embB 4246157 c.-357A>G upstream_gene_variant 0.8 ethambutol
embA 4246164 c.2932T>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4246184 c.-330A>C upstream_gene_variant 0.77 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.81 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.82 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.78 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.78 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.77 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.77 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.73 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.73 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.73 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.74 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.74 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.77 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.74 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.74 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.76 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.76 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.79 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.69 ethambutol
embA 4246359 p.Ala1043Ser missense_variant 0.62 ethambutol
embB 4246367 c.-147C>T upstream_gene_variant 0.68 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.68 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.68 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.68 ethambutol Not assoc w R - Interim
embB 4246400 c.-114G>C upstream_gene_variant 0.65 ethambutol
embB 4247386 c.873T>C synonymous_variant 1.0 ethambutol
embB 4247389 c.876C>G synonymous_variant 1.0 ethambutol
embB 4247395 c.882C>G synonymous_variant 1.0 ethambutol
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.96 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.9 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.94 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.93 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.92 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.95 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.96 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.98 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.96 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.94 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.94 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.94 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.94 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.94 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.94 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.92 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.87 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.87 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.86 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.85 ethambutol
embB 4247638 c.1125G>T synonymous_variant 0.85 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.81 ethambutol Not assoc w R
embB 4247656 c.1143A>G synonymous_variant 0.74 ethambutol
embB 4247659 c.1146C>G synonymous_variant 0.71 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.75 ethambutol
embB 4247683 c.1170C>G synonymous_variant 0.75 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.74 ethambutol
embB 4247716 c.1203C>T synonymous_variant 0.75 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.77 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.77 ethambutol
embB 4247729 p.Gly406Pro missense_variant 0.77 ethambutol
embB 4247746 c.1233C>T synonymous_variant 0.82 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.91 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.92 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.92 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.87 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.87 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.88 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.89 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.89 ethambutol Uncertain significance
embB 4247830 c.1317A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.94 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.93 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.93 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.94 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.94 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.92 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.93 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.93 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.94 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.98 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.98 ethambutol
embB 4247956 c.1443G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 1.0 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.98 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.98 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.98 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.98 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.95 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.97 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.97 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.97 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.95 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.95 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.96 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.95 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.95 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.98 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.97 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.97 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.97 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.97 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.97 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.98 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.98 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.98 ethambutol
embB 4248343 c.1830G>C synonymous_variant 1.0 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.97 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.97 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.97 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.97 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.97 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.97 ethambutol
embB 4248382 c.1869C>G synonymous_variant 0.97 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.97 ethambutol
embB 4248407 p.Leu632Val missense_variant 0.97 ethambutol
embB 4248410 p.Phe633Leu missense_variant 0.97 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.97 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.97 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.97 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.91 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.87 ethambutol
embB 4248475 c.1962G>C synonymous_variant 0.86 ethambutol
embB 4248504 p.Asp664Gly missense_variant 0.67 ethambutol Uncertain significance
embB 4248508 c.1995G>A synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4248512 p.Thr667Ser missense_variant 0.64 ethambutol
embB 4248535 c.2022C>G synonymous_variant 0.6 ethambutol
embB 4249268 p.Asp919Tyr missense_variant 0.58 ethambutol
embB 4249276 c.2763A>G synonymous_variant 0.58 ethambutol
embB 4249277 p.Tyr922Asn missense_variant 0.58 ethambutol
embB 4249282 c.2769A>C synonymous_variant 0.64 ethambutol
embB 4249291 c.2778C>A synonymous_variant 0.7 ethambutol
embB 4249297 c.2784G>C synonymous_variant 0.7 ethambutol
embB 4249312 c.2799C>T synonymous_variant 0.64 ethambutol
embB 4249321 c.2808A>C synonymous_variant 0.64 ethambutol
embB 4249322 p.Ala937Ser missense_variant 0.64 ethambutol
embB 4249325 p.Lys938Asp missense_variant 0.7 ethambutol
embB 4249333 c.2820C>G synonymous_variant 0.7 ethambutol
embB 4249336 c.2823C>G synonymous_variant 0.7 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.7 ethambutol
embB 4249342 c.2829C>G synonymous_variant 0.64 ethambutol
embB 4249348 c.2835G>C synonymous_variant 0.67 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.67 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.72 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.78 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.79 ethambutol
embB 4249384 c.2871G>T synonymous_variant 0.79 ethambutol
embB 4249444 c.2931T>C synonymous_variant 0.64 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.71 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.69 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.7 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.58 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.55 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.55 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.55 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.52 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.55 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.52 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 0.48 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.48 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.47 ethambutol
aftB 4268096 c.741C>G synonymous_variant 0.67 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.67 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.79 ethambutol
aftB 4268123 p.Ser238Gly missense_variant 0.79 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.73 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.79 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.79 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.73 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.73 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.79 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.79 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.79 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.79 ethambutol
aftB 4268213 c.624T>G synonymous_variant 0.77 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.67 ethambutol