Run ID: SRR6045503
Sample name:
Date: 2024-10-04T09:56:11.394875
Number of reads: 220387
Percentage reads mapped: 9.18
Median coverage: 1.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.1.2.1.1 | Euro-American (Haarlem) | RD182 | 0.05 |
| lineage4 | Euro-American | None | 0.98 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.97 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 744 | c.744C>T | synonymous_variant | 0.62 | isoniazid | |
| dnaA | 747 | c.747G>T | synonymous_variant | 0.62 | isoniazid | |
| dnaA | 748 | c.748_750delCTCinsTTG | synonymous_variant | 0.62 | isoniazid | |
| dnaA | 762 | c.762C>T | synonymous_variant | 0.67 | isoniazid | |
| dnaA | 763 | p.Lys255Arg | missense_variant | 0.67 | isoniazid | |
| dnaA | 771 | c.771A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 793 | p.Val265Ile | missense_variant | 0.71 | isoniazid | Uncertain significance |
| dnaA | 801 | c.801G>T | synonymous_variant | 0.75 | isoniazid | |
| dnaA | 804 | c.804G>C | synonymous_variant | 0.75 | isoniazid | |
| dnaA | 819 | c.819C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 837 | c.837A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| gyrB | 6133 | c.894G>C | synonymous_variant | 0.73 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6604 | c.-698G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6631 | c.-671C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6697 | c.1458C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6706 | c.-596G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6715 | c.1476C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6727 | c.-575G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6764 | c.-538C>T | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6772 | c.1533C>G | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6775 | c.-527G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6796 | c.-506C>T | upstream_gene_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6798 | p.Gly520Ala | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Uncertain significance | |||||
| gyrB | 6808 | c.1569C>G | synonymous_variant | 0.74 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6824 | c.1585C>T | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.4 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6866 | c.-436C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6881 | c.-421_-419delTTGinsCTA | upstream_gene_variant | 0.54 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7010 | p.Leu591Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7018 | c.-284G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7024 | c.-278G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7100 | c.1861T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7126 | c.1887G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7159 | c.1920C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7162 | c.-140C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7168 | c.-134C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7397 | c.96G>C | synonymous_variant | 0.62 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 0.7 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7466 | c.165G>C | synonymous_variant | 0.7 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>T | synonymous_variant | 0.7 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>G | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 0.88 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7559 | c.258G>A | synonymous_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7574 | c.273G>C | synonymous_variant | 0.86 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7587 | c.286C>T | synonymous_variant | 0.83 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7595 | c.294C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7619 | c.318C>T | synonymous_variant | 0.84 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7698 | c.397C>A | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7706 | c.405C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7721 | c.420G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7760 | c.459C>T | synonymous_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7781 | c.480G>C | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7782 | p.Gln161Met | missense_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7802 | c.501C>G | synonymous_variant | 0.81 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 0.81 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8882 | c.1581G>A | synonymous_variant | 0.55 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8924 | c.1623C>T | synonymous_variant | 0.56 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8933 | c.1632G>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 0.69 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8967 | p.Ala556Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8993 | c.1692C>T | synonymous_variant | 0.76 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9018 | p.Gln573Lys | missense_variant | 0.81 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9026 | c.1725G>C | synonymous_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9044 | c.1743C>G | synonymous_variant | 0.79 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9063 | p.Ser588Ala | missense_variant | 0.73 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9086 | c.1785C>T | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9092 | c.1791C>G | synonymous_variant | 0.67 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9263 | c.1962C>T | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9329 | c.2028C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| mshA | 575740 | c.393G>A | synonymous_variant | 0.67 | isoniazid | |
| ethionamide | ||||||
| mshA | 575744 | p.Ala133Thr | missense_variant | 0.69 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575792 | p.Asp149Asn | missense_variant | 0.6 | isoniazid | |
| ethionamide | ||||||
| mshA | 575795 | p.Ile150Leu | missense_variant | 0.6 | isoniazid | |
| ethionamide | ||||||
| mshA | 575800 | c.453G>T | synonymous_variant | 0.6 | isoniazid | |
| ethionamide | ||||||
| mshA | 575818 | c.471G>T | synonymous_variant | 0.57 | isoniazid | |
| ethionamide | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575829 | p.Val161Ala | missense_variant | 0.57 | isoniazid | |
| ethionamide | ||||||
| nusG | 734415 | c.162C>G | synonymous_variant | 0.69 | rifampicin | |
| nusG | 734424 | c.171G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734445 | c.192C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
| nusG | 734452 | p.Glu67Gln | missense_variant | 0.68 | rifampicin | Uncertain significance |
| nusG | 734460 | c.207G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734472 | c.219T>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734497 | p.Val82Ile | missense_variant | 0.61 | rifampicin | Uncertain significance |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734544 | c.291C>T | synonymous_variant | 0.62 | rifampicin | |
| nusG | 734556 | c.303C>T | synonymous_variant | 0.45 | rifampicin | |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760244 | c.438G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
| rpoB | 760274 | p.Glu156Asp | missense_variant | 0.66 | rifampicin | Uncertain significance |
| rpoB | 760276 | p.Lys157Met | missense_variant | 0.67 | rifampicin | Uncertain significance |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.42 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 0.58 | rifampicin | |
| rpoB | 760316 | c.510C>G | synonymous_variant | 0.58 | rifampicin | |
| rpoB | 760317 | c.511_513delAGCinsTCG | synonymous_variant | 0.58 | rifampicin | |
| rpoB | 760325 | c.519G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760343 | c.537G>C | synonymous_variant | 0.57 | rifampicin | |
| rpoB | 760357 | p.Thr184Asn | missense_variant | 0.7 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760382 | c.576G>C | synonymous_variant | 0.75 | rifampicin | |
| rpoB | 760400 | c.594G>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 0.81 | rifampicin | Uncertain significance |
| rpoB | 760412 | c.606C>T | synonymous_variant | 0.79 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoB | 760418 | c.612G>A | synonymous_variant | 0.79 | rifampicin | |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760433 | c.627C>T | synonymous_variant | 0.79 | rifampicin | |
| rpoB | 760454 | c.648C>G | synonymous_variant | 0.8 | rifampicin | |
| rpoB | 760457 | c.651C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoB | 760469 | c.663C>T | synonymous_variant | 0.8 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760478 | c.672C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760487 | c.681G>C | synonymous_variant | 0.79 | rifampicin | |
| rpoB | 760502 | c.696C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoB | 760508 | c.702G>A | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 760511 | c.705G>C | synonymous_variant | 0.81 | rifampicin | |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760541 | c.735G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760561 | c.757_758delCG | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 760567 | c.761delCinsGGG | frameshift_variant&missense_variant | 0.86 | rifampicin | |
| rpoB | 760571 | c.765G>C | synonymous_variant | 0.87 | rifampicin | |
| rpoB | 760588 | p.Thr261Ile | missense_variant | 0.95 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760595 | c.789C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760596 | p.Thr264Pro | missense_variant | 0.95 | rifampicin | |
| rpoB | 760607 | c.801G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760668 | p.Thr288Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 760858 | p.Val351Ala | missense_variant | 0.91 | rifampicin | Uncertain significance |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760869 | p.Val355Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760877 | c.1071G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 760883 | c.1077G>C | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760887 | p.Thr361Val | missense_variant | 0.83 | rifampicin | Uncertain significance |
| rpoB | 760910 | c.1104C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 760919 | c.1113C>T | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760973 | c.1167G>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 760997 | c.1191G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761006 | c.1200C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 761054 | c.1248G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 761084 | c.1278C>A | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.72 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761126 | c.1320G>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761147 | c.1341C>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761159 | c.1353G>T | synonymous_variant | 0.8 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761171 | c.1365C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
| rpoB | 761178 | p.Ser458Thr | missense_variant | 0.74 | rifampicin | Uncertain significance |
| rpoB | 761186 | p.Glu460Asp | missense_variant | 0.75 | rifampicin | Uncertain significance |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761192 | c.1386C>T | synonymous_variant | 0.77 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 761219 | c.1413G>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761555 | c.1749G>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 0.86 | rifampicin | |
| rpoB | 761675 | c.1869G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761693 | c.1887G>C | synonymous_variant | 0.86 | rifampicin | |
| rpoB | 761720 | c.1914_1916delCGAinsGG | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761727 | p.Ser641Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | c.1923dupC | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>T | synonymous_variant | 0.85 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761924 | c.2118G>A | synonymous_variant | 0.85 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 0.85 | rifampicin | |
| rpoB | 761933 | c.2127G>C | synonymous_variant | 0.85 | rifampicin | |
| rpoB | 761936 | c.2130C>T | synonymous_variant | 0.89 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761955 | p.Ile717Val | missense_variant | 0.93 | rifampicin | Uncertain significance |
| rpoB | 761969 | c.2163G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761990 | c.2184G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762038 | c.2232C>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762056 | c.2250G>A | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762071 | c.2265C>T | synonymous_variant | 0.89 | rifampicin | |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 0.82 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762134 | c.2328C>A | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 762137 | c.2331C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762194 | c.2388G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoB | 762221 | c.2415G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 762236 | c.2430G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoB | 762245 | c.2439G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762296 | c.2490G>T | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 762879 | p.Met1025Leu | missense_variant | 0.64 | rifampicin | Uncertain significance |
| rpoB | 762894 | c.3088C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
| rpoB | 762899 | c.3093G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| rpoC | 762911 | c.-459C>T | upstream_gene_variant | 0.81 | rifampicin | |
| rpoB | 762917 | c.3111C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoB | 762920 | c.3114C>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 762923 | c.3117C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoB | 762959 | c.3153G>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.83 | rifampicin | |
| rpoB | 762989 | c.3183G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763034 | c.-336C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763082 | c.3276C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763088 | c.3282C>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763142 | c.-228C>G | upstream_gene_variant | 0.88 | rifampicin | |
| rpoB | 763157 | c.3351G>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763172 | c.3366G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoC | 763187 | c.-183C>G | upstream_gene_variant | 0.86 | rifampicin | |
| rpoC | 763375 | c.6C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
| rpoC | 763415 | p.Thr16Ser | missense_variant | 0.67 | rifampicin | Uncertain significance |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 0.57 | rifampicin | Uncertain significance |
| rpoC | 763430 | c.61_63delAGGinsCGT | synonymous_variant | 0.57 | rifampicin | |
| rpoC | 763433 | p.Gln22Asn | missense_variant | 0.53 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 763443 | p.Tyr25Phe | missense_variant | 0.59 | rifampicin | |
| rpoC | 763450 | c.81G>A | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763492 | c.123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763531 | c.162G>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>T | synonymous_variant | 0.8 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 763699 | c.330G>T | synonymous_variant | 0.57 | rifampicin | |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>T | synonymous_variant | 0.58 | rifampicin | |
| rpoC | 763711 | c.342G>C | synonymous_variant | 0.56 | rifampicin | |
| rpoC | 763714 | c.345G>A | synonymous_variant | 0.56 | rifampicin | |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763747 | c.378G>A | synonymous_variant | 0.62 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 0.44 | rifampicin | |
| rpoC | 763796 | p.Met143Leu | missense_variant | 0.5 | rifampicin | |
| rpoC | 763801 | c.432C>T | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763831 | c.462A>G | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 763840 | c.471G>C | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 763844 | p.Arg159Lys | missense_variant | 0.54 | rifampicin | |
| rpoC | 763852 | c.483C>T | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 763857 | p.Glu163Ala | missense_variant | 0.54 | rifampicin | |
| rpoC | 763861 | c.492C>T | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 0.6 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763921 | c.552G>C | synonymous_variant | 0.69 | rifampicin | |
| rpoC | 763933 | c.564C>T | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
| rpoC | 763940 | p.Ala191Ser | missense_variant | 0.75 | rifampicin | Uncertain significance |
| rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764506 | c.1137C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764530 | c.1161C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764533 | c.1164C>A | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764548 | c.1179G>A | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764602 | c.1233C>T | synonymous_variant | 0.88 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764635 | c.1266C>T | synonymous_variant | 0.85 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764810 | p.Pro481Ala | missense_variant | 0.86 | rifampicin | Uncertain significance |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>A | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 0.83 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.74 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 0.74 | rifampicin | Uncertain significance |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765011 | c.1642_1644delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765016 | c.1647C>G | synonymous_variant | 0.75 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765055 | c.1686C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 0.64 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765356 | p.Met663Val | missense_variant | 0.46 | rifampicin | |
| rpoC | 765371 | c.2002C>T | synonymous_variant | 0.43 | rifampicin | |
| rpoC | 765379 | c.2010G>C | synonymous_variant | 0.62 | rifampicin | |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765394 | c.2025G>A | synonymous_variant | 0.59 | rifampicin | |
| rpoC | 765403 | c.2034G>C | synonymous_variant | 0.59 | rifampicin | |
| rpoC | 765404 | p.Leu679Asp | missense_variant | 0.41 | rifampicin | |
| rpoC | 765409 | c.2040T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 0.62 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765449 | p.Ala694Ser | missense_variant | 0.71 | rifampicin | Uncertain significance |
| rpoC | 765454 | c.2085C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765469 | c.2100G>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765480 | p.Tyr704Phe | missense_variant | 0.74 | rifampicin | Uncertain significance |
| rpoC | 765496 | c.2127C>T | synonymous_variant | 0.72 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765861 | p.Phe831Tyr | missense_variant | 0.62 | rifampicin | Uncertain significance |
| rpoC | 765868 | c.2499G>A | synonymous_variant | 0.65 | rifampicin | |
| rpoC | 765871 | c.2502T>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 0.79 | rifampicin | Uncertain significance |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765907 | c.2538G>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 765928 | c.2559C>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765940 | c.2571A>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765946 | c.2577C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 765947 | c.2578T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765962 | c.2593_2595delTTGinsCTT | synonymous_variant | 0.89 | rifampicin | |
| rpoC | 765973 | c.2604C>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766009 | c.2640G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 0.6 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 0.64 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>T | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 766624 | c.3255G>C | synonymous_variant | 0.5 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 766633 | c.3264G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 766693 | c.3324C>A | synonymous_variant | 0.54 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 767008 | c.3639G>A | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 767044 | c.3675G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoC | 767080 | c.3711G>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767100 | p.Lys1244Arg | missense_variant | 0.67 | rifampicin | |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoC | 767107 | c.3738C>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767125 | c.3756G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767138 | c.3769C>T | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| rpoC | 767149 | c.3780C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>T | synonymous_variant | 0.72 | rifampicin | |
| rpoC | 767180 | p.Ala1271Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 767188 | c.3819G>A | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767197 | c.3828G>A | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoC | 767203 | c.3834C>G | synonymous_variant | 0.8 | rifampicin | |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767254 | c.3885G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767264 | p.Ala1299Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 767267 | p.Ala1300Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767284 | c.3915C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781616 | c.57C>G | synonymous_variant | 0.73 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781670 | c.111G>C | synonymous_variant | 0.76 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.8 | streptomycin | |
| rpsL | 781706 | c.147T>G | synonymous_variant | 0.85 | streptomycin | |
| rpsL | 781715 | c.156T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781721 | c.162C>T | synonymous_variant | 0.84 | streptomycin | |
| rpsL | 781725 | p.Lys56Arg | missense_variant | 0.83 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 0.83 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781737 | p.Gln60Ala | missense_variant | 0.83 | streptomycin | |
| rpsL | 781742 | c.183C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 0.8 | streptomycin | |
| rpsL | 781754 | c.195G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 0.84 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 0.86 | streptomycin | Not assoc w R - Interim |
| rpsL | 781802 | c.243G>C | synonymous_variant | 0.93 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781814 | c.255C>T | synonymous_variant | 0.92 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 0.88 | streptomycin | |
| rpsL | 781829 | c.270G>C | synonymous_variant | 0.94 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 0.9 | streptomycin | Not assoc w R - Interim |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 0.89 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.5 | linezolid | |
| rplC | 800639 | c.-170C>T | upstream_gene_variant | 0.59 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 0.57 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.6 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800666 | c.-143C>T | upstream_gene_variant | 0.64 | linezolid | |
| rplC | 800672 | c.-137G>C | upstream_gene_variant | 0.64 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106_-104delTTGinsCTC | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800735 | c.-74C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 0.59 | linezolid | |
| fbiC | 1303812 | c.882C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.6 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305331 | p.Glu801Asn | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305336 | c.2406T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| atpE | 1461113 | c.69C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461146 | c.102G>C | synonymous_variant | 0.84 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461155 | c.111C>G | synonymous_variant | 0.84 | bedaquiline | |
| atpE | 1461161 | c.117C>G | synonymous_variant | 0.84 | bedaquiline | |
| atpE | 1461167 | c.123G>T | synonymous_variant | 0.79 | bedaquiline | |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461179 | c.135G>T | synonymous_variant | 0.83 | bedaquiline | |
| atpE | 1461182 | c.138A>G | synonymous_variant | 0.83 | bedaquiline | |
| atpE | 1461183 | p.Gly47Ser | missense_variant | 0.83 | bedaquiline | |
| atpE | 1461197 | c.153A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461230 | c.186G>T | synonymous_variant | 0.88 | bedaquiline | |
| atpE | 1461233 | c.189A>G | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471931 | n.87delA | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471985 | n.140T>C | non_coding_transcript_exon_variant | 0.91 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 0.91 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472031 | n.186G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472032 | n.187G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472033 | n.188A>C | non_coding_transcript_exon_variant | 0.94 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472035 | n.190G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472040 | n.195T>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472043 | n.198T>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472050 | n.205G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.8 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.92 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472113 | n.268T>C | non_coding_transcript_exon_variant | 0.81 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.92 | kanamycin | Uncertain significance |
| capreomycin | Not assoc w R | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.93 | kanamycin | Uncertain significance |
| capreomycin | Not assoc w R | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472380 | n.535G>C | non_coding_transcript_exon_variant | 0.96 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 0.97 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 0.97 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472566 | n.721G>A | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.4 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
| capreomycin | Not assoc w R | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472658 | n.813G>A | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472734 | n.889C>T | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
| capreomycin | Not assoc w R | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472741 | n.896G>A | non_coding_transcript_exon_variant | 0.73 | kanamycin | Uncertain significance |
| capreomycin | Not assoc w R | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472846 | n.1001C>T | non_coding_transcript_exon_variant | 0.93 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472847 | n.1002G>A | non_coding_transcript_exon_variant | 0.93 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472848 | n.1003T>C | non_coding_transcript_exon_variant | 0.9 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472860 | n.1015C>T | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472861 | n.1016G>A | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472989 | n.1144G>A | non_coding_transcript_exon_variant | 0.91 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.96 | kanamycin | Not assoc w R |
| capreomycin | Not assoc w R | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1473082 | n.1237G>A | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.87 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473099 | n.1254T>A | non_coding_transcript_exon_variant | 0.78 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.94 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.85 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.85 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473121 | n.1276_1278delTTAinsCTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473129 | n.1284C>T | non_coding_transcript_exon_variant | 0.82 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473288 | n.1443_1445delCTCinsTTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.89 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrl | 1473707 | n.50T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473717 | n.60G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473731 | n.74T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473746 | n.89T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473756 | n.99G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473812 | n.155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473814 | n.157A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473829 | n.172G>C | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473831 | n.174G>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473839 | n.182G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473887 | n.230T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473888 | n.231T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473923 | n.266C>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1473935 | n.278C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473950 | n.293G>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524_525insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474184 | n.527C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474185 | n.529delA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474263 | n.606G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474282 | n.625G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474376 | n.719T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474496 | n.839C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474497 | n.840G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474506 | n.849C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474507 | n.850G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474709 | n.1052_1060delGTGGTGTAAinsAATAAGTTAG | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474722 | n.1065T>C | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474743 | n.1086T>G | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475090 | n.1433A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475114 | n.1457C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475120 | n.1463G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475129 | n.1472G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475443 | n.1786G>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475475 | n.1818C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475479 | n.1822C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475480 | n.1823A>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475760 | n.2105_2106delGC | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1475764 | n.2107A>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1475765 | n.2108A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.76 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476295 | n.2638C>T | non_coding_transcript_exon_variant | 0.86 | capreomycin | |
| linezolid | ||||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476311 | n.2654G>A | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
| linezolid | ||||||
| rrl | 1476338 | n.2681C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476353 | n.2696G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| inhA | 1673703 | c.-499C>T | upstream_gene_variant | 0.58 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673710 | c.-492C>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673728 | c.-474_-472delCTCinsTTG | upstream_gene_variant | 0.54 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673736 | c.-466G>C | upstream_gene_variant | 0.54 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673772 | c.-430C>G | upstream_gene_variant | 0.81 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673778 | c.-424C>G | upstream_gene_variant | 0.81 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673784 | c.-418G>A | upstream_gene_variant | 0.87 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673787 | c.-415G>A | upstream_gene_variant | 0.87 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673799 | c.-403T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673808 | c.-394A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673816 | c.-386_-385delGCinsCG | upstream_gene_variant | 0.83 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674601 | p.Leu134Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674609 | c.408G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674687 | c.486G>C | synonymous_variant | 0.55 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833540 | c.-2_-1delATinsC | upstream_gene_variant | 0.89 | pyrazinamide | |
| rpsA | 1833547 | c.6G>A | synonymous_variant | 0.9 | pyrazinamide | |
| rpsA | 1833559 | c.18C>G | synonymous_variant | 0.87 | pyrazinamide | |
| rpsA | 1833583 | c.42C>T | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.93 | pyrazinamide | |
| rpsA | 1833604 | c.63C>T | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833616 | c.75A>T | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.86 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.87 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 0.87 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 0.85 | pyrazinamide | |
| rpsA | 1833685 | c.144G>C | synonymous_variant | 0.8 | pyrazinamide | |
| rpsA | 1833691 | c.150G>A | synonymous_variant | 0.8 | pyrazinamide | |
| rpsA | 1833694 | c.153G>T | synonymous_variant | 0.79 | pyrazinamide | |
| rpsA | 1833697 | c.156C>T | synonymous_variant | 0.8 | pyrazinamide | |
| rpsA | 1833700 | c.159C>T | synonymous_variant | 0.8 | pyrazinamide | |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 0.81 | pyrazinamide | |
| rpsA | 1833724 | c.183C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833733 | c.192C>G | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.88 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833751 | c.210C>T | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 0.83 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 0.8 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833829 | c.288A>G | synonymous_variant | 0.76 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 0.78 | pyrazinamide | |
| rpsA | 1833838 | c.297G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>T | synonymous_variant | 0.78 | pyrazinamide | |
| rpsA | 1833874 | c.333T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833886 | c.345C>G | synonymous_variant | 0.78 | pyrazinamide | |
| rpsA | 1833892 | c.351G>A | synonymous_variant | 0.78 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.79 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 0.86 | pyrazinamide | |
| rpsA | 1833970 | c.429G>C | synonymous_variant | 0.9 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833991 | c.450C>G | synonymous_variant | 0.86 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 0.85 | pyrazinamide | |
| rpsA | 1834012 | c.471G>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 0.83 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834033 | c.492C>T | synonymous_variant | 0.83 | pyrazinamide | |
| rpsA | 1834069 | c.528G>C | synonymous_variant | 0.68 | pyrazinamide | |
| rpsA | 1834073 | p.Lys178Arg | missense_variant | 0.7 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.75 | pyrazinamide | |
| rpsA | 1834123 | c.582C>G | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1834228 | c.687C>A | synonymous_variant | 0.73 | pyrazinamide | |
| rpsA | 1834231 | c.690T>G | synonymous_variant | 0.67 | pyrazinamide | |
| rpsA | 1834234 | c.693G>T | synonymous_variant | 0.67 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 0.67 | pyrazinamide | |
| rpsA | 1834246 | c.705G>T | synonymous_variant | 0.69 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834252 | c.711C>G | synonymous_variant | 0.76 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 0.84 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834339 | c.798C>T | synonymous_variant | 0.79 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 0.81 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834396 | c.855G>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834405 | c.864C>T | synonymous_variant | 0.82 | pyrazinamide | |
| rpsA | 1834408 | c.867C>T | synonymous_variant | 0.82 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834480 | c.939C>G | synonymous_variant | 0.89 | pyrazinamide | |
| rpsA | 1834483 | c.942G>A | synonymous_variant | 0.9 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834520 | p.Ala327Ser | missense_variant | 0.93 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.91 | pyrazinamide | |
| rpsA | 1834552 | c.1011G>T | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834557 | p.Ala339Gly | missense_variant | 0.93 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834612 | c.1071G>C | synonymous_variant | 0.87 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 0.87 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834666 | c.1125G>T | synonymous_variant | 0.79 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 0.79 | pyrazinamide | |
| rpsA | 1834684 | c.1143C>G | synonymous_variant | 0.64 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834700 | p.Gln387Ala | missense_variant | 0.57 | pyrazinamide | |
| rpsA | 1834720 | c.1179C>G | synonymous_variant | 0.53 | pyrazinamide | |
| rpsA | 1834726 | c.1185C>T | synonymous_variant | 0.5 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Asn | missense_variant | 0.64 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.55 | linezolid | |
| tsnR | 1853375 | c.-231G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853384 | c.-222G>T | upstream_gene_variant | 0.47 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>T | upstream_gene_variant | 0.45 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.72 | linezolid | |
| tsnR | 1853444 | c.-162C>T | upstream_gene_variant | 0.67 | linezolid | |
| tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.67 | linezolid | |
| ndh | 2102895 | c.148C>T | synonymous_variant | 0.9 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| kasA | 2517917 | c.-198G>C | upstream_gene_variant | 0.86 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.81 | isoniazid | |
| kasA | 2517953 | c.-162C>T | upstream_gene_variant | 0.73 | isoniazid | |
| kasA | 2517959 | c.-156C>T | upstream_gene_variant | 0.73 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.73 | isoniazid | |
| Rv2477c | 2783182 | c.861C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783275 | c.768C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783287 | p.Leu252Met | missense_variant | 0.47 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783290 | c.753G>C | synonymous_variant | 0.59 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.39 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783317 | c.726G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783341 | c.702C>G | synonymous_variant | 0.81 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783356 | c.687C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 0.81 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.672A>G | synonymous_variant | 0.81 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783377 | c.666C>G | synonymous_variant | 0.81 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783410 | c.633G>C | synonymous_variant | 0.85 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783419 | c.624G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | c.618C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783929 | c.114C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783932 | c.111C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783953 | c.90G>A | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | ||||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| thyA | 3073892 | c.580T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073917 | c.555C>A | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
| thyA | 3073950 | c.522G>T | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
| thyA | 3073971 | c.501C>T | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073980 | c.492C>T | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
| thyA | 3073983 | c.489C>G | synonymous_variant | 0.65 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
| thyA | 3073999 | p.Arg158Lys | missense_variant | 0.71 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074010 | c.462C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074013 | c.459C>T | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
| thyA | 3074022 | c.450C>T | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3074045 | c.427C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074056 | p.Glu139Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074061 | c.411A>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074067 | c.405C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| mtrB | 3625711 | c.903C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625735 | c.879C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625744 | c.870G>A | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3625761 | p.Gln285Glu | missense_variant | 0.78 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3625762 | c.852A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625768 | c.-858G>C | upstream_gene_variant | 0.84 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625792 | c.822G>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625801 | c.-891G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625807 | c.-897C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625819 | p.Glu265Val | missense_variant | 0.81 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 0.81 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625855 | c.759G>A | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626681 | c.-68C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626684 | c.-71G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626717 | c.-104C>T | upstream_gene_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626741 | c.609C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626750 | c.-137T>G | upstream_gene_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626756 | c.594C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626762 | c.588G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626765 | c.585C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626776 | c.-163A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.38 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 0.55 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627056 | c.294C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 0.71 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627083 | c.-470G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 0.69 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 0.8 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627149 | c.-536G>A | upstream_gene_variant | 0.85 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627161 | c.189C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627221 | c.129C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.5 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627242 | p.Gly36Ser | missense_variant | 0.5 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.55 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| rpoA | 3877542 | c.966C>A | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877545 | c.963G>C | synonymous_variant | 0.77 | rifampicin | |
| rpoA | 3877554 | c.954G>C | synonymous_variant | 0.77 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877560 | c.948C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877569 | p.Pro313Thr | missense_variant | 0.88 | rifampicin | Uncertain significance |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877596 | c.912G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoA | 3877602 | c.906C>T | synonymous_variant | 0.88 | rifampicin | |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877662 | c.846C>T | synonymous_variant | 0.8 | rifampicin | |
| rpoA | 3877665 | c.843C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | c.831G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877680 | c.828G>T | synonymous_variant | 0.79 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877728 | c.780C>G | synonymous_variant | 0.71 | rifampicin | |
| rpoA | 3877734 | c.774G>C | synonymous_variant | 0.77 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 0.78 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877752 | p.Asp252Glu | missense_variant | 0.82 | rifampicin | |
| rpoA | 3877758 | c.750G>C | synonymous_variant | 0.82 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877773 | c.735G>C | synonymous_variant | 0.84 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877785 | c.723C>A | synonymous_variant | 0.85 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877856 | c.652T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877860 | c.648C>T | synonymous_variant | 0.82 | rifampicin | |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877881 | c.627G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoA | 3877887 | c.621G>C | synonymous_variant | 0.85 | rifampicin | |
| rpoA | 3877893 | c.615C>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877929 | p.Ile193Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877962 | c.546G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877974 | c.534G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3877977 | p.Lys177Asn | missense_variant | 0.94 | rifampicin | Uncertain significance |
| rpoA | 3877983 | c.525C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878019 | c.489A>C | synonymous_variant | 0.85 | rifampicin | |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 0.85 | rifampicin | |
| rpoA | 3878028 | c.480G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878034 | c.474A>G | synonymous_variant | 0.85 | rifampicin | |
| rpoA | 3878046 | c.462T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 0.86 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878079 | c.429C>T | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 0.89 | rifampicin | |
| rpoA | 3878102 | p.Val136Ile | missense_variant | 0.89 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878175 | c.333G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878205 | c.303T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878259 | c.249G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878274 | c.234G>C | synonymous_variant | 0.89 | rifampicin | |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878301 | c.207C>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878307 | c.201C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878310 | c.198G>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 0.75 | rifampicin | |
| rpoA | 3878373 | c.135G>C | synonymous_variant | 0.67 | rifampicin | |
| rpoA | 3879058 | c.-551C>T | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3879061 | c.-554C>T | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3879073 | c.-566A>G | upstream_gene_variant | 0.57 | rifampicin | |
| rpoA | 3879085 | c.-578C>T | upstream_gene_variant | 0.5 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-615_-614delTTinsAG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.76 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038725 | c.1980C>T | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4038737 | c.1968C>T | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4038743 | c.1962G>A | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>T | synonymous_variant | 0.59 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038779 | c.1926C>A | synonymous_variant | 0.63 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038795 | p.Ser637Thr | missense_variant | 0.64 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038842 | c.1863G>T | synonymous_variant | 0.72 | pyrazinamide | |
| clpC1 | 4038845 | c.1858_1860delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038881 | c.1824C>A | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4038884 | c.1821C>T | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4038896 | c.1809C>A | synonymous_variant | 0.7 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 0.68 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.68 | pyrazinamide | |
| clpC1 | 4038923 | p.Leu594Phe | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038928 | c.1777C>A | synonymous_variant | 0.59 | pyrazinamide | |
| clpC1 | 4038929 | c.1776G>A | synonymous_variant | 0.59 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038932 | c.1773G>T | synonymous_variant | 0.61 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.64 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039031 | c.1674T>C | synonymous_variant | 0.56 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039070 | c.1635G>C | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4039077 | p.Lys543Arg | missense_variant | 0.54 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.57 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039136 | c.1569C>T | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4039139 | c.1566G>A | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039166 | c.1539G>A | synonymous_variant | 0.56 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>T | synonymous_variant | 0.7 | pyrazinamide | |
| clpC1 | 4039238 | c.1467C>T | synonymous_variant | 0.67 | pyrazinamide | |
| clpC1 | 4039265 | c.1440C>T | synonymous_variant | 0.71 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039316 | p.Glu463Asp | missense_variant | 0.75 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>G | synonymous_variant | 0.75 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039336 | c.1369C>T | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039338 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | p.Arg453Ser | missense_variant | 0.75 | pyrazinamide | |
| clpC1 | 4039360 | p.Ser449Arg | missense_variant | 0.76 | pyrazinamide | |
| clpC1 | 4039361 | c.1344C>T | synonymous_variant | 0.76 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039391 | c.1314T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039451 | c.1254G>A | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039457 | c.1248C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039472 | c.1233G>C | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4039478 | c.1227G>C | synonymous_variant | 0.84 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.84 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>T | synonymous_variant | 0.72 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>T | synonymous_variant | 0.71 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 0.71 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.79 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.87 | pyrazinamide | |
| clpC1 | 4039739 | c.966C>G | synonymous_variant | 0.81 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 0.87 | pyrazinamide | |
| clpC1 | 4039805 | c.900C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039907 | c.798G>A | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039943 | c.762G>C | synonymous_variant | 0.85 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039964 | c.741C>G | synonymous_variant | 0.86 | pyrazinamide | |
| clpC1 | 4039975 | p.Asp244Asn | missense_variant | 0.86 | pyrazinamide | Uncertain significance |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039982 | c.723G>A | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040000 | c.705C>T | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040042 | c.663C>T | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040057 | c.648C>T | synonymous_variant | 0.78 | pyrazinamide | |
| clpC1 | 4040087 | c.618G>T | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040126 | c.579C>T | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040132 | c.573C>T | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040141 | c.564C>T | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| glpK | 4138451 | c.1305T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138472 | c.1284G>T | synonymous_variant | 0.64 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>C | synonymous_variant | 0.64 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138565 | c.1191G>C | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| embC | 4240717 | c.855T>C | synonymous_variant | 0.62 | ethambutol | |
| embC | 4240720 | c.858C>T | synonymous_variant | 0.67 | ethambutol | |
| embC | 4240723 | c.861C>G | synonymous_variant | 0.67 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240741 | c.879C>T | synonymous_variant | 0.73 | ethambutol | |
| embC | 4240756 | c.894G>C | synonymous_variant | 0.78 | ethambutol | |
| embC | 4240768 | c.906G>C | synonymous_variant | 0.82 | ethambutol | |
| embC | 4240771 | c.909G>C | synonymous_variant | 0.82 | ethambutol | |
| embC | 4240772 | p.Ser304Ala | missense_variant | 0.82 | ethambutol | |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240781 | p.Ala307Ser | missense_variant | 0.82 | ethambutol | Uncertain significance |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240826 | p.Ala322Ser | missense_variant | 0.76 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol |
