TB-Profiler

Lineage	Family	RDs	Frequency
lineage3.1.2.2	East-African-Indian	RD750	0.07
lineage4	Euro-American	None	0.92
lineage4.9	Euro-American (H37Rv-like)	None	0.92

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
embB	4247448	p.His312Arg	missense_variant	0.48	ethambutol		Mutation from literature
embB	4247580	p.Ala356Val	missense_variant	1.0	ethambutol	Uncertain significance	Mutation from literature
embB	4247663	p.Tyr384Asn	missense_variant	0.93	ethambutol		Mutation from literature
embB	4247708	p.Asn399Asp	missense_variant	1.0	ethambutol		Mutation from literature
embB	4248488	p.Ala659Thr	missense_variant	1.0	ethambutol		Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
gyrB	6172	c.933C>T	synonymous_variant	1.0	levofloxacin
gyrB	6172	c.933C>T	synonymous_variant	1.0	moxifloxacin
gyrB	6190	c.951A>G	synonymous_variant	1.0	levofloxacin
gyrB	6190	c.951A>G	synonymous_variant	1.0	moxifloxacin
gyrB	6214	c.975G>C	synonymous_variant	1.0	levofloxacin
gyrB	6214	c.975G>C	synonymous_variant	1.0	moxifloxacin
gyrB	6238	c.999G>A	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6242	p.Arg335Lys	missense_variant	1.0	levofloxacin
gyrB	6242	p.Arg335Lys	missense_variant	1.0	moxifloxacin
gyrB	6253	c.1014G>C	synonymous_variant	1.0	levofloxacin
gyrB	6253	c.1014G>C	synonymous_variant	1.0	moxifloxacin
gyrB	6265	c.1026C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6265	c.1026C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6280	c.1041T>C	synonymous_variant	1.0	levofloxacin
gyrB	6280	c.1041T>C	synonymous_variant	1.0	moxifloxacin
gyrB	6286	c.1047T>C	synonymous_variant	1.0	levofloxacin
gyrB	6286	c.1047T>C	synonymous_variant	1.0	moxifloxacin
gyrB	6292	c.1053G>A	synonymous_variant	1.0	levofloxacin
gyrB	6292	c.1053G>A	synonymous_variant	1.0	moxifloxacin
gyrB	6298	c.1059C>G	synonymous_variant	1.0	levofloxacin
gyrB	6298	c.1059C>G	synonymous_variant	1.0	moxifloxacin
gyrB	6299	c.1060C>T	synonymous_variant	1.0	levofloxacin
gyrB	6299	c.1060C>T	synonymous_variant	1.0	moxifloxacin
gyrB	6307	c.1068T>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6307	c.1068T>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8555	c.1254G>C	synonymous_variant	1.0	levofloxacin
gyrA	8555	c.1254G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8561	c.1260A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8561	c.1260A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8585	c.1284C>T	synonymous_variant	1.0	levofloxacin
gyrA	8585	c.1284C>T	synonymous_variant	1.0	moxifloxacin
gyrA	8588	c.1287G>A	synonymous_variant	1.0	levofloxacin
gyrA	8588	c.1287G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8619	c.1318T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8619	c.1318T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8627	c.1326C>A	synonymous_variant	0.96	levofloxacin
gyrA	8627	c.1326C>A	synonymous_variant	0.96	moxifloxacin
gyrA	8636	c.1335A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8636	c.1335A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8642	c.1341A>G	synonymous_variant	1.0	levofloxacin
gyrA	8642	c.1341A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8655	p.Ile452Val	missense_variant	1.0	levofloxacin
gyrA	8655	p.Ile452Val	missense_variant	1.0	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8678	c.1377G>A	synonymous_variant	1.0	levofloxacin
gyrA	8678	c.1377G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8694	c.1393C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8694	c.1393C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8711	c.1410A>C	synonymous_variant	1.0	levofloxacin
gyrA	8711	c.1410A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8714	c.1413A>G	synonymous_variant	1.0	levofloxacin
gyrA	8714	c.1413A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8717	c.1416C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8717	c.1416C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8720	c.1419G>A	synonymous_variant	1.0	levofloxacin
gyrA	8720	c.1419G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8729	c.1428T>C	synonymous_variant	1.0	levofloxacin
gyrA	8729	c.1428T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8747	c.1446A>G	synonymous_variant	1.0	levofloxacin
gyrA	8747	c.1446A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8765	p.Asp488Glu	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	8765	p.Asp488Glu	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	8767	p.Arg489Lys	missense_variant	0.93	levofloxacin	Uncertain significance
gyrA	8767	p.Arg489Lys	missense_variant	0.93	moxifloxacin	Uncertain significance
gyrA	8779	p.Asp493Ala	missense_variant	1.0	levofloxacin
gyrA	8779	p.Asp493Ala	missense_variant	1.0	moxifloxacin
gyrA	8786	c.1485T>C	synonymous_variant	1.0	levofloxacin
gyrA	8786	c.1485T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8789	c.1488C>T	synonymous_variant	1.0	levofloxacin
gyrA	8789	c.1488C>T	synonymous_variant	1.0	moxifloxacin
gyrA	8792	c.1491G>C	synonymous_variant	1.0	levofloxacin
gyrA	8792	c.1491G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8798	c.1497C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8798	c.1497C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8810	c.1509A>C	synonymous_variant	1.0	levofloxacin
gyrA	8810	c.1509A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8813	p.Asp504Glu	missense_variant	0.92	levofloxacin	Uncertain significance
gyrA	8813	p.Asp504Glu	missense_variant	0.92	moxifloxacin	Uncertain significance
gyrA	8818	p.Ser506Asn	missense_variant	0.92	levofloxacin	Uncertain significance
gyrA	8818	p.Ser506Asn	missense_variant	0.92	moxifloxacin	Uncertain significance
gyrA	8829	c.1528T>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8829	c.1528T>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8840	c.1539C>G	synonymous_variant	0.93	levofloxacin
gyrA	8840	c.1539C>G	synonymous_variant	0.93	moxifloxacin
gyrA	8852	c.1551T>C	synonymous_variant	0.93	levofloxacin
gyrA	8852	c.1551T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8858	c.1557T>G	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	8858	c.1557T>G	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>T	synonymous_variant	0.92	levofloxacin
gyrA	8873	c.1572A>T	synonymous_variant	0.92	moxifloxacin
gyrA	8888	c.1587C>G	synonymous_variant	0.93	levofloxacin
gyrA	8888	c.1587C>G	synonymous_variant	0.93	moxifloxacin
gyrA	8897	c.1596T>C	synonymous_variant	0.86	levofloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	0.86	moxifloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	8915	c.1614A>G	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	8915	c.1614A>G	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	8924	c.1623C>T	synonymous_variant	0.88	levofloxacin
gyrA	8924	c.1623C>T	synonymous_variant	0.88	moxifloxacin
gyrA	8930	c.1629C>G	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	8930	c.1629C>G	synonymous_variant	0.88	moxifloxacin
gyrA	8933	c.1632G>C	synonymous_variant	0.88	levofloxacin
gyrA	8933	c.1632G>C	synonymous_variant	0.88	moxifloxacin
gyrA	8936	c.1635G>A	synonymous_variant	0.88	levofloxacin
gyrA	8936	c.1635G>A	synonymous_variant	0.88	moxifloxacin
gyrA	8939	c.1638T>C	synonymous_variant	0.88	levofloxacin
gyrA	8939	c.1638T>C	synonymous_variant	0.88	moxifloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.88	levofloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.88	moxifloxacin
gyrA	8946	c.1645_1647delTTGinsCTC	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	8946	c.1645_1647delTTGinsCTC	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	8983	p.Cys561Ser	missense_variant	0.95	levofloxacin
gyrA	8983	p.Cys561Ser	missense_variant	0.95	moxifloxacin
gyrA	8987	c.1686C>G	synonymous_variant	0.95	levofloxacin
gyrA	8987	c.1686C>G	synonymous_variant	0.95	moxifloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.95	levofloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.95	moxifloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.95	levofloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.95	moxifloxacin
gyrA	8998	p.Leu566Trp	missense_variant	0.95	levofloxacin	Uncertain significance
gyrA	8998	p.Leu566Trp	missense_variant	0.95	moxifloxacin	Uncertain significance
gyrA	9003	c.1702C>T	synonymous_variant	0.96	levofloxacin
gyrA	9003	c.1702C>T	synonymous_variant	0.96	moxifloxacin
gyrA	9023	c.1722A>C	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	9029	c.1728T>A	synonymous_variant	0.95	levofloxacin
gyrA	9029	c.1728T>A	synonymous_variant	0.95	moxifloxacin
gyrA	9032	c.1731T>C	synonymous_variant	0.96	levofloxacin
gyrA	9032	c.1731T>C	synonymous_variant	0.96	moxifloxacin
gyrA	9035	c.1734G>C	synonymous_variant	0.9	levofloxacin	Not assoc w R - Interim
gyrA	9035	c.1734G>C	synonymous_variant	0.9	moxifloxacin
gyrA	9038	c.1737C>G	synonymous_variant	0.91	levofloxacin
gyrA	9038	c.1737C>G	synonymous_variant	0.91	moxifloxacin
gyrA	9050	p.Asp583Glu	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	9050	p.Asp583Glu	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	9051	c.1750T>C	synonymous_variant	1.0	levofloxacin
gyrA	9051	c.1750T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9062	c.1761C>A	synonymous_variant	0.94	levofloxacin
gyrA	9062	c.1761C>A	synonymous_variant	0.94	moxifloxacin
gyrA	9071	c.1770G>C	synonymous_variant	0.95	levofloxacin
gyrA	9071	c.1770G>C	synonymous_variant	0.95	moxifloxacin
gyrA	9074	c.1773G>C	synonymous_variant	0.86	levofloxacin
gyrA	9074	c.1773G>C	synonymous_variant	0.86	moxifloxacin
gyrA	9080	c.1779G>T	synonymous_variant	0.93	levofloxacin
gyrA	9080	c.1779G>T	synonymous_variant	0.93	moxifloxacin
gyrA	9089	c.1788G>C	synonymous_variant	0.93	levofloxacin
gyrA	9089	c.1788G>C	synonymous_variant	0.93	moxifloxacin
gyrA	9101	c.1800A>G	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	9101	c.1800A>G	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	9104	c.1803C>A	synonymous_variant	0.96	levofloxacin
gyrA	9104	c.1803C>A	synonymous_variant	0.96	moxifloxacin
gyrA	9110	c.1809G>A	synonymous_variant	0.73	levofloxacin	Not assoc w R - Interim
gyrA	9110	c.1809G>A	synonymous_variant	0.73	moxifloxacin	Not assoc w R - Interim
gyrA	9128	c.1827C>A	synonymous_variant	0.64	levofloxacin	Not assoc w R - Interim
gyrA	9128	c.1827C>A	synonymous_variant	0.64	moxifloxacin	Not assoc w R - Interim
gyrA	9143	c.1842T>C	synonymous_variant	0.96	levofloxacin	Not assoc w R
gyrA	9143	c.1842T>C	synonymous_variant	0.96	moxifloxacin	Not assoc w R
gyrA	9147	p.Gly616Ser	missense_variant	0.62	levofloxacin
gyrA	9147	p.Gly616Ser	missense_variant	0.62	moxifloxacin
gyrA	9153	p.Thr618Glu	missense_variant	0.95	levofloxacin
gyrA	9153	p.Thr618Glu	missense_variant	0.95	moxifloxacin
gyrA	9161	c.1860C>G	synonymous_variant	0.95	levofloxacin
gyrA	9161	c.1860C>G	synonymous_variant	0.95	moxifloxacin
gyrA	9164	c.1863G>C	synonymous_variant	0.5	levofloxacin
gyrA	9164	c.1863G>C	synonymous_variant	0.5	moxifloxacin
gyrA	9167	c.1866C>T	synonymous_variant	0.55	levofloxacin
gyrA	9167	c.1866C>T	synonymous_variant	0.55	moxifloxacin
gyrA	9182	c.1881T>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	9182	c.1881T>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	9183	p.Arg628Lys	missense_variant	0.56	levofloxacin
gyrA	9183	p.Arg628Lys	missense_variant	0.56	moxifloxacin
gyrA	9197	c.1896G>C	synonymous_variant	0.67	levofloxacin
gyrA	9197	c.1896G>C	synonymous_variant	0.67	moxifloxacin
gyrA	9230	c.1929T>C	synonymous_variant	1.0	levofloxacin
gyrA	9230	c.1929T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9236	c.1935G>C	synonymous_variant	0.72	levofloxacin
gyrA	9236	c.1935G>C	synonymous_variant	0.72	moxifloxacin
gyrA	9242	c.1941A>C	synonymous_variant	0.72	levofloxacin
gyrA	9242	c.1941A>C	synonymous_variant	0.72	moxifloxacin
gyrA	9248	c.1947G>C	synonymous_variant	0.71	levofloxacin
gyrA	9248	c.1947G>C	synonymous_variant	0.71	moxifloxacin
gyrA	9252	p.Val651Ile	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	9252	p.Val651Ile	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	9266	c.1965C>T	synonymous_variant	0.71	levofloxacin
gyrA	9266	c.1965C>T	synonymous_variant	0.71	moxifloxacin
gyrA	9284	c.1983T>C	synonymous_variant	1.0	levofloxacin
gyrA	9284	c.1983T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9287	c.1986G>C	synonymous_variant	0.75	levofloxacin
gyrA	9287	c.1986G>C	synonymous_variant	0.75	moxifloxacin
gyrA	9291	c.1990C>T	synonymous_variant	1.0	levofloxacin
gyrA	9291	c.1990C>T	synonymous_variant	1.0	moxifloxacin
gyrA	9296	c.1995T>C	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	9296	c.1995T>C	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	9304	p.Gly668Glu	missense_variant	1.0	levofloxacin
gyrA	9304	p.Gly668Glu	missense_variant	1.0	moxifloxacin
gyrA	9308	p.Asp669Glu	missense_variant	0.97	levofloxacin
gyrA	9308	p.Asp669Glu	missense_variant	0.97	moxifloxacin
gyrA	9315	c.2014C>T	synonymous_variant	0.72	levofloxacin	Not assoc w R - Interim
gyrA	9315	c.2014C>T	synonymous_variant	0.72	moxifloxacin	Not assoc w R - Interim
gyrA	9326	c.2025G>T	synonymous_variant	0.7	levofloxacin
gyrA	9326	c.2025G>T	synonymous_variant	0.7	moxifloxacin
gyrA	9335	c.2034G>C	synonymous_variant	0.32	levofloxacin
gyrA	9335	c.2034G>C	synonymous_variant	0.32	moxifloxacin
gyrA	9338	c.2037G>A	synonymous_variant	0.66	levofloxacin
gyrA	9338	c.2037G>A	synonymous_variant	0.66	moxifloxacin
gyrA	9341	c.2040C>G	synonymous_variant	0.63	levofloxacin
gyrA	9341	c.2040C>G	synonymous_variant	0.63	moxifloxacin
gyrA	9345	c.2044A>C	synonymous_variant	0.62	levofloxacin
gyrA	9345	c.2044A>C	synonymous_variant	0.62	moxifloxacin
gyrA	9374	c.2073G>C	synonymous_variant	0.37	levofloxacin
gyrA	9374	c.2073G>C	synonymous_variant	0.37	moxifloxacin
gyrA	9377	c.2076A>G	synonymous_variant	0.37	levofloxacin	Not assoc w R - Interim
gyrA	9377	c.2076A>G	synonymous_variant	0.37	moxifloxacin	Not assoc w R - Interim
gyrA	9386	c.2085T>C	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	9386	c.2085T>C	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	9389	c.2088C>T	synonymous_variant	0.5	levofloxacin
gyrA	9389	c.2088C>T	synonymous_variant	0.5	moxifloxacin
gyrA	9395	c.2094G>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	9398	c.2097T>C	synonymous_variant	0.92	levofloxacin
gyrA	9398	c.2097T>C	synonymous_variant	0.92	moxifloxacin
mshA	574616	c.-732G>C	upstream_gene_variant	0.93	isoniazid
mshA	574616	c.-732G>C	upstream_gene_variant	0.93	ethionamide
mshA	574640	c.-708G>A	upstream_gene_variant	0.94	isoniazid
mshA	574640	c.-708G>A	upstream_gene_variant	0.94	ethionamide
mshA	574650	c.-698A>C	upstream_gene_variant	0.94	isoniazid
mshA	574650	c.-698A>C	upstream_gene_variant	0.94	ethionamide
mshA	574676	c.-672G>C	upstream_gene_variant	0.93	isoniazid
mshA	574676	c.-672G>C	upstream_gene_variant	0.93	ethionamide
mshA	574683	c.-665T>C	upstream_gene_variant	0.93	isoniazid	Uncertain significance
mshA	574683	c.-665T>C	upstream_gene_variant	0.93	ethionamide
mshA	574688	c.-660G>C	upstream_gene_variant	0.93	isoniazid	Uncertain significance
mshA	574688	c.-660G>C	upstream_gene_variant	0.93	ethionamide	Uncertain significance
mshA	574694	c.-654C>G	upstream_gene_variant	0.93	isoniazid
mshA	574694	c.-654C>G	upstream_gene_variant	0.93	ethionamide
mshA	574712	c.-636A>G	upstream_gene_variant	1.0	isoniazid
mshA	574712	c.-636A>G	upstream_gene_variant	1.0	ethionamide
mshA	574718	c.-630A>G	upstream_gene_variant	1.0	isoniazid
mshA	574718	c.-630A>G	upstream_gene_variant	1.0	ethionamide
mshA	574724	c.-624T>C	upstream_gene_variant	0.92	isoniazid
mshA	574724	c.-624T>C	upstream_gene_variant	0.92	ethionamide
mshA	574731	c.-617A>G	upstream_gene_variant	0.92	isoniazid
mshA	574731	c.-617A>G	upstream_gene_variant	0.92	ethionamide
mshA	574739	c.-609T>C	upstream_gene_variant	0.92	isoniazid
mshA	574739	c.-609T>C	upstream_gene_variant	0.92	ethionamide
mshA	575695	c.348C>G	synonymous_variant	0.93	isoniazid	Not assoc w R - Interim
mshA	575695	c.348C>G	synonymous_variant	0.93	ethionamide
mshA	575704	c.357T>C	synonymous_variant	0.81	isoniazid
mshA	575704	c.357T>C	synonymous_variant	0.81	ethionamide
mshA	575705	c.358T>C	synonymous_variant	0.81	isoniazid
mshA	575705	c.358T>C	synonymous_variant	0.81	ethionamide
mshA	575713	c.366G>A	synonymous_variant	0.85	isoniazid
mshA	575713	c.366G>A	synonymous_variant	0.85	ethionamide
mshA	575719	c.372C>T	synonymous_variant	0.87	isoniazid	Not assoc w R - Interim
mshA	575719	c.372C>T	synonymous_variant	0.87	ethionamide	Not assoc w R - Interim
mshA	575734	c.387T>G	synonymous_variant	0.9	isoniazid
mshA	575734	c.387T>G	synonymous_variant	0.9	ethionamide
mshA	575746	c.399C>G	synonymous_variant	0.9	isoniazid
mshA	575746	c.399C>G	synonymous_variant	0.9	ethionamide
mshA	575767	c.420G>A	synonymous_variant	0.9	isoniazid
mshA	575767	c.420G>A	synonymous_variant	0.9	ethionamide
mshA	575771	p.Val142Ser	missense_variant	0.9	isoniazid
mshA	575771	p.Val142Ser	missense_variant	0.9	ethionamide
mshA	575779	p.Glu144Asp	missense_variant	0.9	isoniazid
mshA	575779	p.Glu144Asp	missense_variant	0.9	ethionamide
mshA	575780	p.Pro145Ala	missense_variant	0.9	isoniazid
mshA	575780	p.Pro145Ala	missense_variant	0.9	ethionamide
mshA	575821	c.474G>C	synonymous_variant	0.85	isoniazid
mshA	575821	c.474G>C	synonymous_variant	0.85	ethionamide
mshA	575824	c.477T>G	synonymous_variant	0.88	isoniazid
mshA	575824	c.477T>G	synonymous_variant	0.88	ethionamide
mshA	575842	c.495G>C	synonymous_variant	0.9	isoniazid
mshA	575842	c.495G>C	synonymous_variant	0.9	ethionamide
mshA	575845	c.498C>G	synonymous_variant	0.89	isoniazid
mshA	575845	c.498C>G	synonymous_variant	0.89	ethionamide
mshA	575848	c.501C>T	synonymous_variant	0.89	isoniazid
mshA	575848	c.501C>T	synonymous_variant	0.89	ethionamide
mshA	575851	c.504C>G	synonymous_variant	0.89	isoniazid
mshA	575851	c.504C>G	synonymous_variant	0.89	ethionamide
mshA	575864	c.517T>C	synonymous_variant	1.0	isoniazid
mshA	575864	c.517T>C	synonymous_variant	1.0	ethionamide
ccsA	619507	c.-384A>G	upstream_gene_variant	0.94	kanamycin
					capreomycin
					amikacin
ccsA	619528	c.-363C>G	upstream_gene_variant	0.7	kanamycin
					capreomycin
					amikacin
ccsA	619531	c.-360T>C	upstream_gene_variant	0.97	kanamycin
					capreomycin
					amikacin
ccsA	619535	c.-356_-354delCAAinsGCG	upstream_gene_variant	0.69	kanamycin
					capreomycin
					amikacin
ccsA	619543	c.-348C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619552	c.-339A>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619555	c.-336C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619561	c.-330G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619570	c.-321G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619574	c.-317G>A	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619579	c.-312G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619584	c.-307A>T	upstream_gene_variant	0.75	kanamycin
					capreomycin
					amikacin
ccsA	619591	c.-300G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619609	c.-282G>C	upstream_gene_variant	0.71	kanamycin
					capreomycin
					amikacin
ccsA	619634	c.-257T>A	upstream_gene_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	619645	c.-246G>C	upstream_gene_variant	0.87	kanamycin
					capreomycin
					amikacin
ccsA	619654	c.-237A>G	upstream_gene_variant	0.92	kanamycin
					capreomycin
					amikacin
ccsA	620317	p.Val143Leu	missense_variant	0.9	kanamycin
					capreomycin
					amikacin
ccsA	620362	p.Ala158Thr	missense_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620367	c.477T>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620373	c.483C>G	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620376	c.486G>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620389	c.499C>T	synonymous_variant	0.87	kanamycin
					capreomycin
					amikacin
ccsA	620412	c.522T>C	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620415	c.525T>C	synonymous_variant	0.86	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
ccsA	620433	c.543C>G	synonymous_variant	0.86	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
ccsA	620439	c.549T>C	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620442	c.552G>C	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620625	c.735A>C	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620631	c.741T>G	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620649	c.759A>G	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620661	c.771C>G	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620685	c.795G>A	synonymous_variant	0.71	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin
ccsA	620698	p.Val270Ile	missense_variant	0.74	kanamycin
					capreomycin
					amikacin
ccsA	620712	c.822G>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620715	c.825C>T	synonymous_variant	0.8	kanamycin
					capreomycin
					amikacin
ccsA	620721	c.831G>A	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620733	c.843G>C	synonymous_variant	0.94	kanamycin
					capreomycin
					amikacin
ccsA	620739	c.849A>G	synonymous_variant	0.94	kanamycin
					capreomycin
					amikacin
ccsA	620742	c.852G>C	synonymous_variant	0.94	kanamycin
					capreomycin
					amikacin
ccsA	620748	c.858T>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620778	c.888T>C	synonymous_variant	0.96	kanamycin
					capreomycin
					amikacin
ccsA	620781	c.891C>G	synonymous_variant	0.89	kanamycin
					capreomycin
					amikacin
ccsA	620783	p.Ala298Val	missense_variant	0.89	kanamycin
					capreomycin
					amikacin
ccsA	620787	c.897C>A	synonymous_variant	0.89	kanamycin
					capreomycin
					amikacin
ccsA	620796	c.906C>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620829	c.939G>C	synonymous_variant	0.85	kanamycin
					capreomycin
					amikacin
ccsA	620835	c.945C>G	synonymous_variant	0.9	kanamycin
					capreomycin
					amikacin
Rv0565c	657183	c.288G>A	synonymous_variant	0.8	ethionamide
Rv0565c	657193	p.Met93Thr	missense_variant	1.0	ethionamide
Rv0565c	657196	p.Asp92Ala	missense_variant	1.0	ethionamide
Rv0565c	657200	p.Thr91Ala	missense_variant	1.0	ethionamide	Uncertain significance
Rv0565c	657210	c.261C>T	synonymous_variant	0.73	ethionamide	Not assoc w R - Interim
Rv0565c	657213	c.258C>T	synonymous_variant	0.73	ethionamide
Rv0565c	657219	p.Ala84Val	missense_variant	1.0	ethionamide
Rv0565c	657233	p.Ile80Val	missense_variant	1.0	ethionamide
Rv0565c	657240	p.Glu77Lys	missense_variant	0.69	ethionamide
Rv0565c	657252	c.219G>C	synonymous_variant	0.56	ethionamide
Rv0565c	657255	c.216G>A	synonymous_variant	0.59	ethionamide
Rv0565c	657259	p.Tyr71Phe	missense_variant	0.94	ethionamide
Rv0565c	657261	c.210C>G	synonymous_variant	0.41	ethionamide
Rv0565c	657264	c.207T>C	synonymous_variant	0.41	ethionamide
Rv0565c	657267	c.204G>C	synonymous_variant	0.41	ethionamide
Rv0565c	657294	c.177C>A	synonymous_variant	0.58	ethionamide
Rv0565c	657300	c.171C>G	synonymous_variant	0.44	ethionamide
Rv0565c	657306	c.165C>T	synonymous_variant	0.56	ethionamide
Rv0565c	657312	c.159C>T	synonymous_variant	0.46	ethionamide
Rv0565c	657318	c.153T>C	synonymous_variant	1.0	ethionamide
Rv0565c	657324	c.147C>G	synonymous_variant	1.0	ethionamide
Rv0565c	657327	c.144C>G	synonymous_variant	0.64	ethionamide
Rv0565c	657337	p.Arg45Gln	missense_variant	1.0	ethionamide	Uncertain significance
Rv0565c	657342	c.129T>C	synonymous_variant	1.0	ethionamide
Rv0565c	657347	c.124A>C	synonymous_variant	1.0	ethionamide
Rv0565c	657348	c.123A>G	synonymous_variant	1.0	ethionamide
Rv0565c	657356	p.Ile39Val	missense_variant	0.7	ethionamide
hadA	731687	c.-243_-237delGCAAGACinsATGTGCA	upstream_gene_variant	0.92	isoniazid
hadA	731695	c.-235C>T	upstream_gene_variant	0.81	isoniazid
hadA	731698	c.-232T>G	upstream_gene_variant	0.93	isoniazid
hadA	731708	c.-222G>A	upstream_gene_variant	1.0	isoniazid
hadA	731711	c.-219T>C	upstream_gene_variant	1.0	isoniazid
hadA	731726	c.-204C>G	upstream_gene_variant	0.88	isoniazid
hadA	731729	c.-201C>T	upstream_gene_variant	0.88	isoniazid
hadA	731753	c.-177A>C	upstream_gene_variant	0.83	isoniazid
hadA	731756	c.-174C>T	upstream_gene_variant	0.88	isoniazid
hadA	731774	c.-156T>C	upstream_gene_variant	0.83	isoniazid
hadA	732305	p.Ile126Val	missense_variant	1.0	isoniazid
hadA	732308	p.Val127Ile	missense_variant	1.0	isoniazid
hadA	732314	p.Asn129Asp	missense_variant	0.4	isoniazid
hadA	732319	c.390G>A	synonymous_variant	0.4	isoniazid
hadA	732321	p.Glu131Ala	missense_variant	1.0	isoniazid
hadA	732329	p.Leu134Val	missense_variant	1.0	isoniazid	Uncertain significance
hadA	732337	c.408G>A	synonymous_variant	0.55	isoniazid
hadA	732346	c.417T>C	synonymous_variant	0.45	isoniazid
hadA	732378	c.450_452dupAGA	disruptive_inframe_insertion	1.0	isoniazid
hadA	732396	p.Gly156Ala	missense_variant	1.0	isoniazid
hadA	732398	p.Ala157Thr	missense_variant	1.0	isoniazid
nusG	734407	p.Val52Ile	missense_variant	1.0	rifampicin
nusG	734439	c.186C>G	synonymous_variant	0.57	rifampicin
nusG	734451	c.198G>C	synonymous_variant	1.0	rifampicin
nusG	734454	c.201A>G	synonymous_variant	0.6	rifampicin
nusG	734475	c.222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734478	c.225C>G	synonymous_variant	0.6	rifampicin	Not assoc w R - Interim
rpoB	760046	c.240G>C	synonymous_variant	1.0	rifampicin
rpoB	760070	c.264T>G	synonymous_variant	1.0	rifampicin
rpoB	760091	c.285G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760101	c.295T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760109	c.303C>T	synonymous_variant	0.59	rifampicin
rpoB	760112	c.306T>C	synonymous_variant	0.95	rifampicin
rpoB	760118	c.312T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760121	c.315T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760130	p.Asp108Glu	missense_variant	0.93	rifampicin	Uncertain significance
rpoB	760139	c.333A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760142	c.336C>G	synonymous_variant	0.96	rifampicin
rpoB	760145	c.339C>G	synonymous_variant	0.52	rifampicin
rpoB	760181	c.375T>A	synonymous_variant	0.93	rifampicin
rpoB	760184	c.378A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760196	c.390C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760235	c.429T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760244	c.438G>C	synonymous_variant	0.52	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	0.58	rifampicin	Not assoc w R - Interim
rpoB	760298	c.492G>C	synonymous_variant	0.59	rifampicin	Not assoc w R - Interim
rpoB	760307	c.501T>C	synonymous_variant	1.0	rifampicin
rpoB	760310	c.504G>C	synonymous_variant	1.0	rifampicin
rpoB	760328	c.522G>C	synonymous_variant	1.0	rifampicin
rpoB	760331	c.525G>C	synonymous_variant	1.0	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760358	c.552C>G	synonymous_variant	0.33	rifampicin
rpoB	760361	c.555T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760370	c.564C>G	synonymous_variant	1.0	rifampicin
rpoB	760376	p.Asp190Glu	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760380	p.Thr192Leu	missense_variant	0.96	rifampicin
rpoB	760406	c.600G>C	synonymous_variant	0.81	rifampicin
rpoB	760412	c.606C>G	synonymous_variant	1.0	rifampicin
rpoB	760424	c.618C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760475	c.669A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760484	c.678A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760522	p.Ser239Asn	missense_variant	0.93	rifampicin	Uncertain significance
rpoB	760532	c.726T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Thr	missense_variant	0.92	rifampicin
rpoB	760541	c.735G>C	synonymous_variant	0.69	rifampicin	Not assoc w R - Interim
rpoB	760547	c.741G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760563	p.Arg253Met	missense_variant	0.85	rifampicin	Uncertain significance
rpoB	760591	p.Val262Ala	missense_variant	0.88	rifampicin
rpoB	760611	c.805T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760646	c.840C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760655	c.849A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760661	c.855A>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>C	synonymous_variant	0.96	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760724	c.918T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760730	c.924T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760757	c.951T>C	synonymous_variant	1.0	rifampicin
rpoB	760817	c.1011A>G	synonymous_variant	1.0	rifampicin
rpoB	760820	c.1014T>C	synonymous_variant	1.0	rifampicin
rpoB	760826	c.1020C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760830	c.1024T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760841	c.1035T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760845	p.Thr347Pro	missense_variant	1.0	rifampicin
rpoB	760856	c.1050C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760916	c.1110C>G	synonymous_variant	0.79	rifampicin
rpoB	760919	c.1113C>G	synonymous_variant	0.75	rifampicin
rpoB	760925	c.1119T>C	synonymous_variant	1.0	rifampicin
rpoB	760928	c.1122G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760931	c.1125C>G	synonymous_variant	1.0	rifampicin
rpoB	760937	c.1131G>A	synonymous_variant	0.75	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760973	c.1167G>C	synonymous_variant	0.58	rifampicin
rpoB	760982	c.1176G>T	synonymous_variant	1.0	rifampicin
rpoB	760985	c.1179G>T	synonymous_variant	1.0	rifampicin
rpoB	760991	c.1185G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761006	c.1200C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761015	c.1209G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761021	c.1215G>C	synonymous_variant	1.0	rifampicin
rpoB	761027	c.1221A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761036	c.1230G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761057	c.1251G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761102	c.1296A>G	synonymous_variant	1.0	rifampicin
rpoB	761129	c.1323G>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	761132	c.1326G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761133	c.1327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761153	c.1347G>C	synonymous_variant	0.75	rifampicin
rpoB	761165	c.1359G>C	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoB	761180	c.1374A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761189	c.1383T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761195	c.1389G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761207	c.1401C>T	synonymous_variant	0.74	rifampicin
rpoB	761213	c.1407G>C	synonymous_variant	0.74	rifampicin
rpoB	761219	c.1413G>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	761249	c.1443A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761255	c.1449T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761261	c.1455G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761282	c.1476C>G	synonymous_variant	0.33	rifampicin
rpoB	761306	c.1500C>G	synonymous_variant	0.64	rifampicin
rpoB	761312	c.1506G>C	synonymous_variant	0.67	rifampicin
rpoB	761327	c.1521A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761330	c.1524G>C	synonymous_variant	0.61	rifampicin
rpoB	761345	c.1539G>T	synonymous_variant	0.56	rifampicin
rpoB	761354	c.1548C>T	synonymous_variant	1.0	rifampicin
rpoB	761360	c.1554T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761362	p.Ser519Thr	missense_variant	1.0	rifampicin
rpoB	761374	p.Val523Glu	missense_variant	1.0	rifampicin
rpoB	761414	c.1608A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761510	c.1704T>C	synonymous_variant	1.0	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761570	c.1764T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761606	c.1800C>G	synonymous_variant	1.0	rifampicin
rpoB	761615	c.1809A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761648	c.1842T>C	synonymous_variant	1.0	rifampicin
rpoB	761690	c.1884G>C	synonymous_variant	0.75	rifampicin
rpoB	761735	c.1929C>G	synonymous_variant	0.91	rifampicin
rpoB	761750	c.1944G>C	synonymous_variant	0.93	rifampicin
rpoB	761765	c.1959T>C	synonymous_variant	0.89	rifampicin
rpoB	761772	p.His656Ala	missense_variant	0.89	rifampicin
rpoB	761778	p.Asn658Asp	missense_variant	0.89	rifampicin
rpoB	761791	p.Arg662His	missense_variant	0.88	rifampicin
rpoB	761813	c.2007T>C	synonymous_variant	0.91	rifampicin
rpoB	761828	c.2022C>T	synonymous_variant	0.55	rifampicin
rpoB	761834	c.2028T>C	synonymous_variant	0.9	rifampicin
rpoB	761837	c.2031C>T	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoB	761848	p.Cys681Ser	missense_variant	0.9	rifampicin
rpoB	761852	c.2046C>G	synonymous_variant	0.94	rifampicin
rpoB	761858	c.2052G>C	synonymous_variant	0.94	rifampicin
rpoB	761873	c.2067A>C	synonymous_variant	0.95	rifampicin
rpoB	761885	c.2079T>C	synonymous_variant	0.96	rifampicin
rpoB	761906	c.2100C>G	synonymous_variant	0.62	rifampicin
rpoB	761909	c.2103T>C	synonymous_variant	0.95	rifampicin
rpoB	761912	c.2106T>C	synonymous_variant	1.0	rifampicin
rpoB	761916	p.Asp704Asn	missense_variant	1.0	rifampicin
rpoB	761948	c.2142G>C	synonymous_variant	0.57	rifampicin	Not assoc w R - Interim
rpoB	761954	c.2148C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762008	c.2202C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762014	c.2208C>T	synonymous_variant	1.0	rifampicin
rpoB	762017	c.2211A>G	synonymous_variant	0.52	rifampicin	Not assoc w R - Interim
rpoB	762053	c.2247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762062	c.2256T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	762101	c.2295C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	0.94	rifampicin	Uncertain significance
rpoB	762131	c.2325C>G	synonymous_variant	0.91	rifampicin
rpoB	762134	c.2328C>G	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
rpoB	762140	c.2334G>C	synonymous_variant	0.44	rifampicin
rpoB	762143	c.2337T>C	synonymous_variant	0.91	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	0.4	rifampicin	Not assoc w R - Interim
rpoB	762167	c.2361T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762176	c.2370T>C	synonymous_variant	0.43	rifampicin	Not assoc w R - Interim
rpoB	762185	c.2379G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	762206	c.2400C>G	synonymous_variant	0.55	rifampicin
rpoB	762233	c.2427G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762246	c.2440C>T	synonymous_variant	0.67	rifampicin
rpoB	762254	c.2448T>G	synonymous_variant	0.94	rifampicin
rpoB	762257	c.2451C>G	synonymous_variant	0.94	rifampicin
rpoB	762266	c.2460T>C	synonymous_variant	0.94	rifampicin
rpoB	762284	c.2478G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762314	c.2508C>T	synonymous_variant	0.77	rifampicin
rpoB	762317	c.2511A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762329	c.2523G>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	762338	c.2532T>C	synonymous_variant	0.97	rifampicin
rpoB	762347	c.2541T>C	synonymous_variant	0.96	rifampicin
rpoB	762362	p.Glu852Asp	missense_variant	0.96	rifampicin
rpoB	762369	c.2563T>C	synonymous_variant	0.96	rifampicin
rpoC	762395	c.-975G>C	upstream_gene_variant	0.37	rifampicin
rpoC	762398	c.-972T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762401	c.-969G>C	upstream_gene_variant	1.0	rifampicin
rpoB	762404	c.2598T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762410	c.-960T>C	upstream_gene_variant	1.0	rifampicin
rpoB	762413	c.2607G>A	synonymous_variant	0.52	rifampicin	Not assoc w R - Interim
rpoB	762416	c.2610A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	762419	c.-951C>G	upstream_gene_variant	0.52	rifampicin
rpoB	762431	c.2625C>T	synonymous_variant	0.41	rifampicin	Not assoc w R - Interim
rpoC	762434	c.-936T>C	upstream_gene_variant	0.54	rifampicin
rpoB	762449	c.2643C>A	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	762467	c.-903C>T	upstream_gene_variant	0.44	rifampicin
rpoB	762470	c.2664G>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoB	762488	c.2682G>C	synonymous_variant	0.4	rifampicin	Not assoc w R - Interim
rpoB	762489	p.Val895His	missense_variant	0.38	rifampicin
rpoC	762509	c.-861T>G	upstream_gene_variant	0.95	rifampicin
rpoB	762510	p.Ala902Pro	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	762521	c.-849C>T	upstream_gene_variant	0.45	rifampicin
rpoC	762533	c.-837T>C	upstream_gene_variant	0.93	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	0.93	rifampicin
rpoC	762537	c.-833T>C	upstream_gene_variant	0.93	rifampicin
rpoC	762551	c.-819C>T	upstream_gene_variant	0.9	rifampicin
rpoC	762794	c.-576C>G	upstream_gene_variant	1.0	rifampicin
rpoB	762799	p.Ala998Gly	missense_variant	0.6	rifampicin	Uncertain significance
rpoB	762810	p.Ala1002Ser	missense_variant	0.46	rifampicin
rpoB	762813	p.Met1003Val	missense_variant	0.92	rifampicin
rpoB	762818	c.3012C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762827	c.3021G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762857	c.3051C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762860	c.3054G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762863	c.3057T>C	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoC	762917	c.-453C>T	upstream_gene_variant	0.27	rifampicin
rpoB	762929	c.3123G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762983	c.-387C>G	upstream_gene_variant	0.39	rifampicin
rpoC	762989	c.-381G>C	upstream_gene_variant	0.57	rifampicin
rpoB	762995	c.3189G>T	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoC	763013	c.-357C>G	upstream_gene_variant	0.54	rifampicin
rpoB	763028	c.3222T>C	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoB	763031	c.3225T>C	synonymous_variant	1.0	rifampicin	Not assoc w R
rpoB	763034	c.3228C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763040	c.3234C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763050	c.-320C>T	upstream_gene_variant	0.54	rifampicin
rpoB	763070	c.3264T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763082	c.3276C>T	synonymous_variant	0.61	rifampicin	Not assoc w R - Interim
rpoB	763085	c.3279C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763115	c.3309T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763127	c.3321G>C	synonymous_variant	0.59	rifampicin	Not assoc w R - Interim
rpoB	763136	c.3330C>T	synonymous_variant	0.42	rifampicin	Not assoc w R - Interim
rpoC	763158	c.-212C>T	upstream_gene_variant	0.5	rifampicin
rpoB	763166	c.3360A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763169	c.-201A>G	upstream_gene_variant	0.46	rifampicin
rpoC	763190	c.-180C>T	upstream_gene_variant	0.55	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	1.0	rifampicin
rpoC	763206	c.-164_-162delAGTinsTCG	upstream_gene_variant	1.0	rifampicin
rpoB	763214	c.3408T>C	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
rpoC	763226	c.-144A>G	upstream_gene_variant	1.0	rifampicin
rpoB	763227	c.3421C>T	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
rpoB	763238	c.3432T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763241	c.-129G>A	upstream_gene_variant	0.38	rifampicin
rpoC	763250	c.-120C>T	upstream_gene_variant	0.35	rifampicin
rpoC	763253	c.-117G>C	upstream_gene_variant	0.9	rifampicin
rpoC	763256	c.-114G>A	upstream_gene_variant	0.6	rifampicin
rpoB	763268	c.3462C>G	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoC	763402	c.33C>T	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	763409	c.40_42delCTTinsTTG	synonymous_variant	0.45	rifampicin
rpoC	763414	c.45T>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	763441	c.72C>T	synonymous_variant	0.96	rifampicin
rpoC	763444	c.75T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763456	c.87A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763486	c.117T>G	synonymous_variant	0.97	rifampicin
rpoC	763528	c.159G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763573	c.204G>C	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
rpoC	763594	c.225C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	763603	c.234C>T	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoC	763618	c.249C>T	synonymous_variant	0.48	rifampicin
rpoC	763633	c.264T>C	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
rpoC	763636	c.267T>C	synonymous_variant	0.95	rifampicin
rpoC	763660	c.291T>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763669	c.300C>G	synonymous_variant	0.42	rifampicin	Not assoc w R - Interim
rpoC	763675	c.306C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763696	c.327T>C	synonymous_variant	0.49	rifampicin	Not assoc w R - Interim
rpoC	763702	c.333C>G	synonymous_variant	0.51	rifampicin	Not assoc w R - Interim
rpoC	763703	c.334_336delTCGinsAGC	synonymous_variant	0.42	rifampicin
rpoC	763709	c.340C>T	synonymous_variant	0.41	rifampicin
rpoC	763714	c.345G>C	synonymous_variant	0.41	rifampicin	Not assoc w R - Interim
rpoC	763717	c.348T>C	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
rpoC	763723	c.354G>C	synonymous_variant	0.53	rifampicin
rpoC	763726	c.357C>T	synonymous_variant	0.44	rifampicin
rpoC	763732	c.363C>G	synonymous_variant	0.97	rifampicin
rpoC	763741	c.372C>T	synonymous_variant	0.97	rifampicin
rpoC	763744	c.375G>C	synonymous_variant	0.97	rifampicin
rpoC	763765	c.396T>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763771	c.402C>T	synonymous_variant	0.6	rifampicin	Not assoc w R - Interim
rpoC	763774	c.405G>C	synonymous_variant	0.38	rifampicin
rpoC	763780	c.411C>G	synonymous_variant	0.6	rifampicin
rpoC	763792	p.Glu141Asp	missense_variant	0.58	rifampicin
rpoC	763801	c.432C>G	synonymous_variant	0.62	rifampicin
rpoC	763807	c.438T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763816	c.447C>G	synonymous_variant	0.38	rifampicin
rpoC	763835	p.Ala156Met	missense_variant	0.4	rifampicin
rpoC	763851	p.Ala161Gly	missense_variant	0.57	rifampicin
rpoC	763853	p.Val162Ile	missense_variant	0.42	rifampicin
rpoC	763858	c.489A>G	synonymous_variant	1.0	rifampicin
rpoC	763872	p.Gly168Ala	missense_variant	0.97	rifampicin
rpoC	763876	p.Glu169Asp	missense_variant	0.98	rifampicin
rpoC	763877	c.508_510delCTAinsTTG	synonymous_variant	0.37	rifampicin
rpoC	763888	c.519G>C	synonymous_variant	0.97	rifampicin
rpoC	763891	c.522G>C	synonymous_variant	0.97	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	0.97	rifampicin
rpoC	763900	c.531G>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
rpoC	763936	c.567C>G	synonymous_variant	0.97	rifampicin
rpoC	763939	c.570G>A	synonymous_variant	0.53	rifampicin
rpoC	763945	c.576T>C	synonymous_variant	0.41	rifampicin
rpoC	763951	c.582G>A	synonymous_variant	0.96	rifampicin
rpoC	763960	c.591T>C	synonymous_variant	0.38	rifampicin	Not assoc w R - Interim
rpoC	763963	c.594C>G	synonymous_variant	0.63	rifampicin
rpoC	763967	p.Gly200Ser	missense_variant	0.63	rifampicin
rpoC	763972	c.603C>T	synonymous_variant	0.62	rifampicin
rpoC	763987	c.618C>T	synonymous_variant	0.68	rifampicin
rpoC	763996	c.627T>C	synonymous_variant	0.98	rifampicin
rpoC	764005	c.636G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764011	c.642T>C	synonymous_variant	0.69	rifampicin
rpoC	764024	c.655T>C	synonymous_variant	1.0	rifampicin
rpoC	764040	p.Ser224Thr	missense_variant	1.0	rifampicin
rpoC	764044	c.675T>G	synonymous_variant	1.0	rifampicin
rpoC	764059	c.690G>T	synonymous_variant	1.0	rifampicin
rpoC	764083	c.714A>G	synonymous_variant	1.0	rifampicin
rpoC	764098	c.729A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764101	c.732C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764102	p.Val245Ile	missense_variant	0.36	rifampicin
rpoC	764112	p.Tyr248Phe	missense_variant	0.35	rifampicin
rpoC	764116	c.747C>T	synonymous_variant	0.33	rifampicin	Not assoc w R - Interim
rpoC	764140	c.771C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764159	c.790C>T	synonymous_variant	0.54	rifampicin
rpoC	764167	c.798G>A	synonymous_variant	0.56	rifampicin
rpoC	764188	c.819A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764195	p.Ser276Ile	missense_variant	1.0	rifampicin
rpoC	764203	c.834G>C	synonymous_variant	0.43	rifampicin
rpoC	764206	c.837T>C	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoC	764215	c.846A>C	synonymous_variant	1.0	rifampicin
rpoC	764218	c.849C>T	synonymous_variant	0.5	rifampicin
rpoC	764236	c.867G>A	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoC	764242	c.873C>T	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
rpoC	764245	c.876C>A	synonymous_variant	0.48	rifampicin
rpoC	764246	c.877_879delCTCinsTTG	synonymous_variant	0.5	rifampicin
rpoC	764257	c.888G>C	synonymous_variant	0.5	rifampicin
rpoC	764263	c.894G>C	synonymous_variant	0.5	rifampicin
rpoC	764266	c.897T>C	synonymous_variant	1.0	rifampicin
rpoC	764269	c.900G>C	synonymous_variant	0.52	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	0.52	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764338	c.969G>A	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	764353	c.984G>C	synonymous_variant	0.67	rifampicin
rpoC	764365	c.996C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764405	c.1036A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764419	c.1050C>G	synonymous_variant	0.72	rifampicin
rpoC	764428	c.1059G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764431	c.1062G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764434	c.1065A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764446	c.1077T>C	synonymous_variant	1.0	rifampicin
rpoC	764449	c.1080G>C	synonymous_variant	1.0	rifampicin
rpoC	764452	c.1083T>C	synonymous_variant	1.0	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764489	c.1120C>T	synonymous_variant	0.76	rifampicin
rpoC	764497	c.1128A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764510	c.1141C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	764521	c.1152T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764527	c.1158C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>C	synonymous_variant	0.94	rifampicin
rpoC	764539	c.1170C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764554	c.1185C>T	synonymous_variant	1.0	rifampicin
rpoC	764560	c.1191T>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	764566	c.1197C>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	764575	c.1206T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764581	c.1212T>C	synonymous_variant	0.72	rifampicin
rpoC	764593	c.1224C>T	synonymous_variant	0.96	rifampicin
rpoC	764611	c.1242G>T	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>C	synonymous_variant	0.85	rifampicin
rpoC	764651	c.1282_1284delTCGinsAGC	synonymous_variant	0.55	rifampicin
rpoC	764752	c.1383G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764764	c.1395T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764809	c.1440C>T	synonymous_variant	1.0	rifampicin	Not assoc w R
rpoC	764815	c.1446A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764827	c.1458G>C	synonymous_variant	0.61	rifampicin	Not assoc w R - Interim
rpoC	764858	c.1489T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764872	c.1503A>G	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoC	764887	c.1518G>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519_1521delTTGinsCTC	synonymous_variant	0.97	rifampicin
rpoC	764896	c.1527C>T	synonymous_variant	0.55	rifampicin
rpoC	764902	c.1533C>T	synonymous_variant	0.55	rifampicin
rpoC	764911	c.1542A>G	synonymous_variant	0.97	rifampicin
rpoC	764923	c.1554A>G	synonymous_variant	0.65	rifampicin	Not assoc w R - Interim
rpoC	764932	c.1563C>G	synonymous_variant	0.95	rifampicin
rpoC	764935	c.1566T>C	synonymous_variant	0.36	rifampicin
rpoC	764948	c.1579T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764968	c.1599T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764995	c.1626C>G	synonymous_variant	0.65	rifampicin	Not assoc w R
rpoC	765007	c.1638T>G	synonymous_variant	0.35	rifampicin	Not assoc w R - Interim
rpoC	765013	c.1644C>T	synonymous_variant	0.35	rifampicin	Not assoc w R - Interim
rpoC	765019	c.1650A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765034	c.1665T>C	synonymous_variant	0.7	rifampicin
rpoC	765040	c.1671T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765041	c.1672T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765047	c.1678T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765053	c.1684_1685delTCinsAG	synonymous_variant	1.0	rifampicin
rpoC	765073	c.1704G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765076	c.1707A>G	synonymous_variant	1.0	rifampicin
rpoC	765079	c.1710T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765082	c.1713G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765089	c.1720T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765103	c.1734G>T	synonymous_variant	0.93	rifampicin
rpoC	765300	p.Val644Ala	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	765319	c.1950A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765334	c.1965C>T	synonymous_variant	0.56	rifampicin
rpoC	765343	c.1974G>A	synonymous_variant	0.56	rifampicin
rpoC	765346	c.1977C>G	synonymous_variant	0.41	rifampicin
rpoC	765349	c.1980T>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
rpoC	765352	c.1983G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765367	c.1998C>G	synonymous_variant	0.44	rifampicin
rpoC	765370	c.2001G>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
rpoC	765383	p.Met672Leu	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	765391	c.2022C>T	synonymous_variant	0.35	rifampicin
rpoC	765404	p.Leu679Val	missense_variant	0.62	rifampicin
rpoC	765409	c.2040T>C	synonymous_variant	1.0	rifampicin
rpoC	765412	c.2043T>C	synonymous_variant	0.36	rifampicin
rpoC	765421	c.2052C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765478	c.2109T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	765499	c.2130C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765529	c.2160C>T	synonymous_variant	0.96	rifampicin
rpoC	765541	c.2172C>G	synonymous_variant	0.95	rifampicin
rpoC	765553	c.2184C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765556	c.2187G>C	synonymous_variant	0.95	rifampicin
rpoC	765559	c.2190G>C	synonymous_variant	0.58	rifampicin
rpoC	765580	c.2211G>C	synonymous_variant	0.61	rifampicin
rpoC	765613	p.His748Gln	missense_variant	0.57	rifampicin
rpoC	765625	c.2256C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765631	p.Asp754Glu	missense_variant	0.67	rifampicin
rpoC	765700	c.2331T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765734	c.2365T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765739	c.2370G>T	synonymous_variant	0.94	rifampicin
rpoC	765751	c.2382C>G	synonymous_variant	0.67	rifampicin
rpoC	765772	c.2403C>G	synonymous_variant	0.95	rifampicin
rpoC	765784	c.2415C>G	synonymous_variant	0.95	rifampicin
rpoC	765787	c.2418C>T	synonymous_variant	0.64	rifampicin
rpoC	765793	c.2424C>G	synonymous_variant	0.95	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	0.96	rifampicin
rpoC	765811	c.2442T>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoC	765814	c.2445A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	765826	c.2457T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765835	c.2466C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765850	c.2481G>C	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
rpoC	765883	c.2514C>G	synonymous_variant	1.0	rifampicin
rpoC	765886	c.2517C>G	synonymous_variant	1.0	rifampicin
rpoC	765892	c.2523T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765934	c.2565C>T	synonymous_variant	0.47	rifampicin
rpoC	765937	c.2568T>C	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoC	765967	c.2598C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765982	c.2613C>G	synonymous_variant	1.0	rifampicin
rpoC	765994	c.2625A>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766010	c.2641_2642delTCinsAG	synonymous_variant	0.77	rifampicin
rpoC	766021	c.2652G>C	synonymous_variant	1.0	rifampicin
rpoC	766027	c.2658G>C	synonymous_variant	0.75	rifampicin
rpoC	766030	c.2661C>G	synonymous_variant	0.75	rifampicin
rpoC	766036	c.2667C>T	synonymous_variant	0.78	rifampicin
rpoC	766043	p.Gln892Glu	missense_variant	0.81	rifampicin
rpoC	766054	c.2685C>G	synonymous_variant	0.87	rifampicin
rpoC	766082	p.Ala905Gln	missense_variant	1.0	rifampicin
rpoC	766096	c.2727G>C	synonymous_variant	1.0	rifampicin
rpoC	766258	c.2889T>C	synonymous_variant	0.92	rifampicin
rpoC	766273	c.2904T>C	synonymous_variant	1.0	rifampicin
rpoC	766274	p.Ala969Thr	missense_variant	1.0	rifampicin
rpoC	766280	p.Ser971Gly	missense_variant	1.0	rifampicin
rpoC	766288	c.2919C>G	synonymous_variant	1.0	rifampicin
rpoC	766309	c.2940G>A	synonymous_variant	0.47	rifampicin
rpoC	766312	c.2943T>G	synonymous_variant	0.53	rifampicin
rpoC	766315	c.2946C>G	synonymous_variant	0.48	rifampicin
rpoC	766321	c.2952C>G	synonymous_variant	0.52	rifampicin
rpoC	766327	c.2958C>A	synonymous_variant	0.48	rifampicin
rpoC	766345	c.2976T>C	synonymous_variant	0.52	rifampicin
rpoC	766348	c.2979A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766357	c.2988C>T	synonymous_variant	0.5	rifampicin
rpoC	766363	c.2994G>C	synonymous_variant	0.5	rifampicin
rpoC	766369	c.3000C>G	synonymous_variant	0.53	rifampicin
rpoC	766381	c.3012C>T	synonymous_variant	1.0	rifampicin
rpoC	766384	c.3015A>G	synonymous_variant	1.0	rifampicin
rpoC	766393	c.3024C>G	synonymous_variant	0.54	rifampicin
rpoC	766402	c.3033C>G	synonymous_variant	0.54	rifampicin
rpoC	766408	c.3039C>G	synonymous_variant	0.45	rifampicin
rpoC	766408	c.3039C>T	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoC	766411	c.3042C>G	synonymous_variant	0.45	rifampicin
rpoC	766426	c.3057C>T	synonymous_variant	1.0	rifampicin
rpoC	766447	c.3078T>C	synonymous_variant	0.62	rifampicin
rpoC	766456	c.3087C>G	synonymous_variant	0.35	rifampicin
rpoC	766462	c.3093G>C	synonymous_variant	0.63	rifampicin
rpoC	766483	c.3114G>C	synonymous_variant	0.76	rifampicin
rpoC	766484	p.Val1039Ile	missense_variant	0.72	rifampicin	Uncertain significance
rpoC	766492	c.3123T>C	synonymous_variant	1.0	rifampicin
rpoC	766522	c.3153C>G	synonymous_variant	1.0	rifampicin
rpoC	766528	c.3159T>C	synonymous_variant	1.0	rifampicin
rpoC	766530	p.Arg1054His	missense_variant	0.29	rifampicin
rpoC	766540	p.Asp1057Glu	missense_variant	0.65	rifampicin
rpoC	766549	c.3180G>C	synonymous_variant	1.0	rifampicin
rpoC	766573	c.3204T>C	synonymous_variant	1.0	rifampicin
rpoC	766582	c.3213C>G	synonymous_variant	0.48	rifampicin
rpoC	766583	p.Gly1072Ser	missense_variant	0.44	rifampicin
rpoC	766591	c.3222A>G	synonymous_variant	0.44	rifampicin
rpoC	766594	c.3225G>C	synonymous_variant	0.96	rifampicin
rpoC	766597	c.3228C>G	synonymous_variant	0.46	rifampicin	Not assoc w R - Interim
rpoC	766607	p.Ile1080Leu	missense_variant	0.97	rifampicin
rpoC	766630	c.3261G>T	synonymous_variant	0.9	rifampicin
rpoC	766657	c.3288A>G	synonymous_variant	0.38	rifampicin
rpoC	766660	c.3291G>A	synonymous_variant	0.57	rifampicin
rpoC	766666	c.3297C>G	synonymous_variant	0.53	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	0.98	rifampicin
rpoC	766673	p.Gly1102Asn	missense_variant	0.44	rifampicin
rpoC	766700	c.3331C>T	synonymous_variant	0.5	rifampicin
rpoC	766726	c.3357T>C	synonymous_variant	0.98	rifampicin
rpoC	766733	c.3364C>T	synonymous_variant	0.52	rifampicin
rpoC	766738	c.3369G>C	synonymous_variant	1.0	rifampicin
rpoC	766741	c.3372G>C	synonymous_variant	0.51	rifampicin
rpoC	766750	c.3381C>G	synonymous_variant	0.51	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766774	c.3405T>C	synonymous_variant	1.0	rifampicin
rpoC	766798	c.3429C>G	synonymous_variant	0.37	rifampicin	Not assoc w R - Interim
rpoC	766801	c.3432C>G	synonymous_variant	0.98	rifampicin
rpoC	766804	c.3435A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766861	c.3492G>C	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoC	766864	c.3495G>C	synonymous_variant	0.97	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	0.96	rifampicin
rpoC	766933	c.3564A>G	synonymous_variant	0.95	rifampicin
rpoC	766945	c.3576A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766963	c.3594T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766972	c.3603G>C	synonymous_variant	0.63	rifampicin
rpoC	766996	c.3627C>G	synonymous_variant	1.0	rifampicin
rpoC	767002	c.3633G>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoC	767009	c.3640_3642delTCGinsAGC	synonymous_variant	1.0	rifampicin
rpoC	767014	c.3645G>C	synonymous_variant	1.0	rifampicin
rpoC	767033	c.3664_3666delTCGinsAGT	synonymous_variant	1.0	rifampicin
rpoC	767059	c.3690T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767062	c.3693C>A	synonymous_variant	1.0	rifampicin
rpoC	767098	c.3729T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767119	c.3750A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767134	c.3765C>A	synonymous_variant	1.0	rifampicin
rpoC	767158	c.3789T>A	synonymous_variant	1.0	rifampicin
rpoC	767167	c.3798C>G	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoC	767180	p.Ala1271Gln	missense_variant	1.0	rifampicin
rpoC	767191	c.3822C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767206	c.3837C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767209	c.3840T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767212	c.3843G>C	synonymous_variant	0.36	rifampicin
rpoC	767221	c.3852C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767230	c.3861G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpsL	781754	c.195G>C	synonymous_variant	1.0	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	1.0	streptomycin
rpsL	781772	c.213C>A	synonymous_variant	1.0	streptomycin
rpsL	781808	c.249C>T	synonymous_variant	1.0	streptomycin
rpsL	781811	c.252C>T	synonymous_variant	0.67	streptomycin
rpsL	781832	c.273T>C	synonymous_variant	1.0	streptomycin
rpsL	781838	c.279G>C	synonymous_variant	0.52	streptomycin
rpsL	781841	c.282C>G	synonymous_variant	0.52	streptomycin
rpsL	781865	c.306G>C	synonymous_variant	1.0	streptomycin
rpsL	781868	c.309T>C	synonymous_variant	1.0	streptomycin
rpsL	781871	c.312G>C	synonymous_variant	1.0	streptomycin
rpsL	781877	c.318T>C	synonymous_variant	0.46	streptomycin
rpsL	781892	c.333A>G	synonymous_variant	1.0	streptomycin
rpsL	781898	c.339A>T	synonymous_variant	1.0	streptomycin
rpsL	781916	c.357T>C	synonymous_variant	1.0	streptomycin
rpsL	781929	p.Gly124Ser	missense_variant	1.0	streptomycin	Uncertain significance
rpsL	781933	c.374G>A	splice_region_variant&stop_retained_variant	0.68	streptomycin
rplC	800516	c.-293G>T	upstream_gene_variant	1.0	linezolid
rplC	800537	c.-272C>T	upstream_gene_variant	0.46	linezolid
rplC	800540	c.-269T>C	upstream_gene_variant	1.0	linezolid
rplC	800567	c.-242A>G	upstream_gene_variant	1.0	linezolid
rplC	800582	c.-227C>G	upstream_gene_variant	1.0	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	1.0	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	1.0	linezolid
rplC	800627	c.-182C>T	upstream_gene_variant	1.0	linezolid
rplC	800648	c.-161A>T	upstream_gene_variant	1.0	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	1.0	linezolid
rplC	800693	c.-116A>G	upstream_gene_variant	1.0	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	1.0	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	1.0	linezolid
rplC	800720	c.-89T>C	upstream_gene_variant	0.87	linezolid
rplC	800723	c.-86C>G	upstream_gene_variant	1.0	linezolid
rplC	800747	c.-62C>G	upstream_gene_variant	1.0	linezolid
rplC	800771	c.-38C>T	upstream_gene_variant	0.93	linezolid
rplC	800794	c.-15A>G	upstream_gene_variant	1.0	linezolid
rplC	800796	c.-13A>G	upstream_gene_variant	1.0	linezolid
rplC	800798	c.-10_-9delGG	upstream_gene_variant	1.0	linezolid
rplC	800814	c.6A>G	synonymous_variant	1.0	linezolid
rplC	800817	c.9A>T	synonymous_variant	1.0	linezolid
rplC	800844	c.36T>C	synonymous_variant	1.0	linezolid
rplC	801341	p.Leu178Gln	missense_variant	1.0	linezolid
rplC	801348	c.540T>G	synonymous_variant	1.0	linezolid
rplC	801357	c.549T>C	synonymous_variant	1.0	linezolid
rplC	801423	c.615G>C	synonymous_variant	0.83	linezolid
rplC	801426	c.618C>G	synonymous_variant	0.83	linezolid
rplC	801427	p.Met207Val	missense_variant	0.83	linezolid
rplC	801438	c.630T>C	synonymous_variant	0.86	linezolid
rplC	801442	p.Ile212Val	missense_variant	0.86	linezolid
fbiC	1303512	c.582T>C	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1303534	p.Ser202Ala	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303538	p.Arg203Leu	missense_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1303545	c.615A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303575	c.645G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303578	c.648G>A	synonymous_variant	0.84	pretomanid
					delamanid
					clofazimine
fbiC	1303584	c.654C>G	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1303596	c.666G>C	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1303605	c.675C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303608	c.678G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303614	c.684C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303617	c.687C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303620	c.690C>T	synonymous_variant	0.77	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1303629	c.699C>T	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1303632	c.702T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303659	c.729T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303661	p.Val244Ala	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303674	c.744C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303686	c.756C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303695	c.765T>C	synonymous_variant	0.32	pretomanid
					delamanid
					clofazimine
fbiC	1303704	c.774T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303708	c.778T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303729	c.799_801delCTAinsTTG	synonymous_variant	0.53	pretomanid
					delamanid
					clofazimine
fbiC	1303732	p.Ser268Ala	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303737	c.807G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303746	c.816T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303749	c.819G>C	synonymous_variant	0.48	pretomanid
					delamanid
					clofazimine
fbiC	1303750	c.820_822delTTAinsCTG	synonymous_variant	0.52	pretomanid
					delamanid
					clofazimine
fbiC	1303755	c.825T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303761	c.831T>C	synonymous_variant	0.48	pretomanid
					delamanid
					clofazimine
fbiC	1303785	c.855G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303789	p.Ile287Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303797	c.867A>G	synonymous_variant	0.64	pretomanid
					delamanid
					clofazimine
fbiC	1303818	c.888C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303836	c.906G>C	synonymous_variant	0.64	pretomanid
					delamanid
					clofazimine
fbiC	1303846	p.Phe306Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303854	c.924T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303860	c.930A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303884	c.954T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303905	c.975G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304496	c.1566T>A	synonymous_variant	0.73	pretomanid
					delamanid
					clofazimine
fbiC	1304502	c.1572G>C	synonymous_variant	0.73	pretomanid
					delamanid
					clofazimine
fbiC	1304526	c.1596T>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1304532	c.1602G>C	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1304533	c.1603T>C	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1304541	c.1611C>G	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1304544	c.1614T>C	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1304546	p.Val539Ala	missense_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1304559	p.Glu543Asp	missense_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1304565	c.1635C>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1304568	c.1638T>C	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1304574	c.1644C>G	synonymous_variant	0.68	pretomanid
					delamanid
					clofazimine
fbiC	1304580	c.1650T>C	synonymous_variant	0.96	pretomanid
					delamanid
					clofazimine
fbiC	1304610	c.1680C>G	synonymous_variant	0.62	pretomanid
					delamanid
					clofazimine
fbiC	1304613	c.1683T>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304625	c.1695C>T	synonymous_variant	0.6	pretomanid
					delamanid
					clofazimine
fbiC	1304634	c.1704C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304640	c.1710A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304646	c.1716T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304658	c.1728C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304694	c.1764A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304778	c.1848T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304808	c.1878C>G	synonymous_variant	0.67	pretomanid
					delamanid
					clofazimine
fbiC	1304811	c.1881C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304817	c.1887T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304829	c.1899T>C	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiC	1304856	c.1926C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304869	c.1939C>T	synonymous_variant	0.8	pretomanid
					delamanid
					clofazimine
fbiC	1304875	p.Ile649Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304883	p.Glu651Asp	missense_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1304891	p.Ile654Thr	missense_variant	0.65	pretomanid
					delamanid
					clofazimine
fbiC	1304893	p.Gly655Ser	missense_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1304907	c.1977C>G	synonymous_variant	0.67	pretomanid
					delamanid
					clofazimine
fbiC	1304910	c.1980G>C	synonymous_variant	0.65	pretomanid
					delamanid
					clofazimine
fbiC	1304916	c.1986T>C	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1304928	c.1998T>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1304937	c.2007G>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1304958	c.2028T>G	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1304983	c.2053C>T	synonymous_variant	0.67	pretomanid
					delamanid
					clofazimine
fbiC	1304994	c.2064A>G	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304995	p.Leu689Met	missense_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1305006	c.2076A>G	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1305012	c.2082G>C	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1305015	c.2085G>C	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
rrs	1473105	n.1260G>A	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTT	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473288	n.1443C>T	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473290	n.1445C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473291	n.1446G>T	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473797	n.140G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473797	n.140G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473813	n.156C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473813	n.156C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473831	n.174G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473831	n.174G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473887	n.230T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473887	n.230T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473888	n.231T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473888	n.231T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473899	n.242A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473899	n.242A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473918	n.261C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473918	n.261C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474018	n.361G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474018	n.361G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474030	n.373G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474030	n.373G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474061	n.404T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474061	n.404T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474089	n.432C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474089	n.432C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474100	n.443C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474100	n.443C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474110	n.453A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474110	n.453A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474111	n.454T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474111	n.454T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474130	n.473C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474130	n.473C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
inhA	1674507	c.306G>A	synonymous_variant	1.0	isoniazid
inhA	1674507	c.306G>A	synonymous_variant	1.0	ethionamide
inhA	1674522	c.321G>C	synonymous_variant	1.0	isoniazid
inhA	1674522	c.321G>C	synonymous_variant	1.0	ethionamide
inhA	1674534	c.333G>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674534	c.333G>C	synonymous_variant	1.0	ethionamide
inhA	1674537	c.336C>A	synonymous_variant	1.0	isoniazid
inhA	1674537	c.336C>A	synonymous_variant	1.0	ethionamide
inhA	1674540	c.339C>T	synonymous_variant	1.0	isoniazid
inhA	1674540	c.339C>T	synonymous_variant	1.0	ethionamide
inhA	1674542	p.Ala114Glu	missense_variant	1.0	isoniazid
inhA	1674542	p.Ala114Glu	missense_variant	1.0	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	1.0	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	1.0	ethionamide
inhA	1674555	c.354G>A	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674555	c.354G>A	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674561	c.360C>T	synonymous_variant	1.0	isoniazid
inhA	1674561	c.360C>T	synonymous_variant	1.0	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	0.92	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	0.92	ethionamide
inhA	1674588	c.387G>A	synonymous_variant	0.92	isoniazid
inhA	1674588	c.387G>A	synonymous_variant	0.92	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	0.92	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	0.92	ethionamide
inhA	1674601	p.Leu134Val	missense_variant	0.94	isoniazid
inhA	1674601	p.Leu134Val	missense_variant	0.94	ethionamide
inhA	1674618	c.417C>T	synonymous_variant	0.91	isoniazid
inhA	1674618	c.417C>T	synonymous_variant	0.91	ethionamide
inhA	1674619	p.Pro140Ser	missense_variant	0.91	isoniazid
inhA	1674619	p.Pro140Ser	missense_variant	0.91	ethionamide
inhA	1674624	c.423A>T	synonymous_variant	0.9	isoniazid
inhA	1674624	c.423A>T	synonymous_variant	0.9	ethionamide
inhA	1674627	c.426T>C	synonymous_variant	0.9	isoniazid
inhA	1674627	c.426T>C	synonymous_variant	0.9	ethionamide
inhA	1674669	c.468G>C	synonymous_variant	0.91	isoniazid
inhA	1674669	c.468G>C	synonymous_variant	0.91	ethionamide
inhA	1674687	c.486G>A	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
inhA	1674687	c.486G>A	synonymous_variant	0.92	ethionamide	Not assoc w R - Interim
inhA	1674690	c.489C>G	synonymous_variant	0.92	isoniazid
inhA	1674690	c.489C>G	synonymous_variant	0.92	ethionamide
inhA	1674696	c.495G>A	synonymous_variant	0.92	isoniazid
inhA	1674696	c.495G>A	synonymous_variant	0.92	ethionamide
inhA	1674703	c.502T>C	synonymous_variant	0.93	isoniazid
inhA	1674703	c.502T>C	synonymous_variant	0.93	ethionamide
inhA	1674718	c.517A>C	synonymous_variant	0.94	isoniazid
inhA	1674718	c.517A>C	synonymous_variant	0.94	ethionamide
inhA	1674729	c.528G>A	synonymous_variant	1.0	isoniazid
inhA	1674729	c.528G>A	synonymous_variant	1.0	ethionamide
inhA	1674745	p.Tyr182Ala	missense_variant	1.0	isoniazid
inhA	1674745	p.Tyr182Ala	missense_variant	1.0	ethionamide
inhA	1674756	c.555T>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674756	c.555T>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674759	c.558G>C	synonymous_variant	1.0	isoniazid
inhA	1674759	c.558G>C	synonymous_variant	1.0	ethionamide
inhA	1674765	c.564C>T	synonymous_variant	1.0	isoniazid
inhA	1674765	c.564C>T	synonymous_variant	1.0	ethionamide
inhA	1674774	c.573A>C	synonymous_variant	1.0	isoniazid
inhA	1674774	c.573A>C	synonymous_variant	1.0	ethionamide
inhA	1674777	c.576C>A	synonymous_variant	1.0	isoniazid
inhA	1674777	c.576C>A	synonymous_variant	1.0	ethionamide
inhA	1674780	c.579T>G	synonymous_variant	1.0	isoniazid
inhA	1674780	c.579T>G	synonymous_variant	1.0	ethionamide
inhA	1674792	c.591G>C	synonymous_variant	1.0	isoniazid
inhA	1674792	c.591G>C	synonymous_variant	1.0	ethionamide
inhA	1674801	c.600T>C	synonymous_variant	1.0	isoniazid
inhA	1674801	c.600T>C	synonymous_variant	1.0	ethionamide
inhA	1674820	c.619_621delCTCinsTTG	synonymous_variant	1.0	isoniazid
inhA	1674820	c.619_621delCTCinsTTG	synonymous_variant	1.0	ethionamide
inhA	1674828	c.627G>A	synonymous_variant	1.0	isoniazid
inhA	1674828	c.627G>A	synonymous_variant	1.0	ethionamide
inhA	1674846	p.Ile215Met	missense_variant	1.0	isoniazid
inhA	1674846	p.Ile215Met	missense_variant	1.0	ethionamide
inhA	1674870	c.669T>C	synonymous_variant	1.0	isoniazid
inhA	1674870	c.669T>C	synonymous_variant	1.0	ethionamide
inhA	1674876	c.675C>G	synonymous_variant	1.0	isoniazid
inhA	1674876	c.675C>G	synonymous_variant	1.0	ethionamide
inhA	1674879	c.678T>C	synonymous_variant	1.0	isoniazid
inhA	1674879	c.678T>C	synonymous_variant	1.0	ethionamide
inhA	1674888	c.687C>T	synonymous_variant	1.0	isoniazid
inhA	1674888	c.687C>T	synonymous_variant	1.0	ethionamide
inhA	1674939	c.738G>A	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
inhA	1674939	c.738G>A	synonymous_variant	0.92	ethionamide	Not assoc w R - Interim
inhA	1674942	c.741T>C	synonymous_variant	0.91	isoniazid
inhA	1674942	c.741T>C	synonymous_variant	0.91	ethionamide
inhA	1674966	c.765T>C	synonymous_variant	0.92	isoniazid
inhA	1674966	c.765T>C	synonymous_variant	0.92	ethionamide
inhA	1674967	p.Asp256Thr	missense_variant	0.92	isoniazid
inhA	1674967	p.Asp256Thr	missense_variant	0.92	ethionamide
inhA	1674993	c.792G>C	synonymous_variant	0.92	isoniazid
inhA	1674993	c.792G>C	synonymous_variant	0.92	ethionamide
inhA	1674994	p.His265Ser	missense_variant	0.92	isoniazid
inhA	1674994	p.His265Ser	missense_variant	0.92	ethionamide
inhA	1675006	c.805_807delCTCinsTTG	synonymous_variant	0.92	isoniazid
inhA	1675006	c.805_807delCTCinsTTG	synonymous_variant	0.92	ethionamide
rpsA	1833532	c.-10A>C	upstream_gene_variant	0.92	pyrazinamide
rpsA	1833554	p.Thr5Ala	missense_variant	0.59	pyrazinamide	Uncertain significance
rpsA	1833568	c.27G>C	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
rpsA	1833589	c.48A>T	synonymous_variant	0.95	pyrazinamide
rpsA	1833595	c.54T>C	synonymous_variant	0.95	pyrazinamide
rpsA	1833613	c.72C>A	synonymous_variant	0.43	pyrazinamide
rpsA	1833619	c.78A>C	synonymous_variant	0.46	pyrazinamide
rpsA	1833661	c.120A>G	synonymous_variant	0.94	pyrazinamide
rpsA	1833667	c.126C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1833703	c.162C>T	synonymous_variant	0.45	pyrazinamide	Not assoc w R - Interim
rpsA	1833721	c.180A>G	synonymous_variant	0.48	pyrazinamide
rpsA	1833724	c.183C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833742	c.201A>G	synonymous_variant	0.53	pyrazinamide
rpsA	1833745	c.204G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833748	c.207C>G	synonymous_variant	0.52	pyrazinamide
rpsA	1833760	c.219C>T	synonymous_variant	0.42	pyrazinamide	Not assoc w R - Interim
rpsA	1833787	c.246C>G	synonymous_variant	0.52	pyrazinamide
rpsA	1833790	c.249T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833793	c.252C>T	synonymous_variant	0.48	pyrazinamide
rpsA	1833802	c.261A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833808	c.267G>C	synonymous_variant	0.46	pyrazinamide
rpsA	1833811	c.270G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833832	c.291G>A	synonymous_variant	0.54	pyrazinamide
rpsA	1833838	c.297G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833859	c.318C>T	synonymous_variant	0.66	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833895	c.354G>C	synonymous_variant	0.69	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833940	c.399C>G	synonymous_variant	0.4	pyrazinamide
rpsA	1833949	c.408T>C	synonymous_variant	0.61	pyrazinamide
rpsA	1833970	c.429G>A	synonymous_variant	0.55	pyrazinamide
rpsA	1833971	c.430C>T	synonymous_variant	0.45	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834000	c.459G>C	synonymous_variant	0.43	pyrazinamide
rpsA	1834015	c.474G>C	synonymous_variant	0.52	pyrazinamide
rpsA	1834021	c.480C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834030	c.489C>G	synonymous_variant	0.54	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834105	c.564C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834150	c.609G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834153	c.612T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834154	p.Asn205Gln	missense_variant	1.0	pyrazinamide
rpsA	1834157	c.616T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834162	c.621A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834165	c.624A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834177	c.636A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834186	c.645C>G	synonymous_variant	0.62	pyrazinamide
rpsA	1834189	c.648G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834195	c.654G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834210	c.669C>T	synonymous_variant	0.43	pyrazinamide
rpsA	1834222	c.681T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834225	c.684C>G	synonymous_variant	0.5	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834297	c.756C>T	synonymous_variant	0.56	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834336	c.795C>G	synonymous_variant	0.63	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834366	c.825A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834375	c.834G>A	synonymous_variant	0.75	pyrazinamide
rpsA	1834396	c.855G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834423	c.882G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834456	c.915T>G	synonymous_variant	0.66	pyrazinamide
rpsA	1834465	c.924T>C	synonymous_variant	0.96	pyrazinamide
rpsA	1834468	c.927A>G	synonymous_variant	0.96	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	0.96	pyrazinamide
rpsA	1834546	c.1005T>C	synonymous_variant	0.92	pyrazinamide
rpsA	1834555	c.1014T>G	synonymous_variant	0.46	pyrazinamide
rpsA	1834603	c.1062G>A	synonymous_variant	0.73	pyrazinamide
rpsA	1834609	c.1068T>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834612	c.1071G>A	synonymous_variant	0.73	pyrazinamide	Not assoc w R - Interim
rpsA	1834633	c.1092A>G	synonymous_variant	0.94	pyrazinamide
rpsA	1834639	c.1098T>C	synonymous_variant	0.94	pyrazinamide
rpsA	1834654	c.1113G>A	synonymous_variant	0.92	pyrazinamide
rpsA	1834690	c.1149T>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834699	p.Glu386Asp	missense_variant	0.63	pyrazinamide
rpsA	1834732	c.1191T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834733	p.Ala398Ser	missense_variant	0.38	pyrazinamide
rpsA	1834738	c.1197A>G	synonymous_variant	0.43	pyrazinamide
rpsA	1834747	c.1206A>G	synonymous_variant	0.62	pyrazinamide
rpsA	1834751	p.Leu404Met	missense_variant	0.62	pyrazinamide
rpsA	1834756	c.1215G>A	synonymous_variant	0.62	pyrazinamide
rpsA	1834759	c.1218A>C	synonymous_variant	0.62	pyrazinamide
rpsA	1834765	p.Glu408Asp	missense_variant	1.0	pyrazinamide
rpsA	1834766	p.Lys409Ala	missense_variant	0.67	pyrazinamide
rpsA	1834780	c.1239A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834789	c.1248T>C	synonymous_variant	1.0	pyrazinamide
tsnR	1853370	c.-236_-234delGCAinsTCG	upstream_gene_variant	1.0	linezolid
tsnR	1853387	c.-219T>G	upstream_gene_variant	1.0	linezolid
tsnR	1853394	c.-212_-211delCTinsGC	upstream_gene_variant	0.93	linezolid
bacA	2064972	c.-244T>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064978	c.-250G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064979	c.-251C>T	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064984	c.-256A>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064993	c.-265T>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
pncA	2289943	c.-702T>G	upstream_gene_variant	1.0	pyrazinamide
pncA	2289948	c.-707C>T	upstream_gene_variant	1.0	pyrazinamide
pncA	2289949	c.-708A>G	upstream_gene_variant	1.0	pyrazinamide
pncA	2289987	c.-746C>T	upstream_gene_variant	1.0	pyrazinamide
pncA	2289991	c.-750G>C	upstream_gene_variant	1.0	pyrazinamide
pncA	2289994	c.-753A>G	upstream_gene_variant	1.0	pyrazinamide
pncA	2289997	c.-756G>C	upstream_gene_variant	1.0	pyrazinamide
pncA	2290009	c.-768A>G	upstream_gene_variant	0.94	pyrazinamide
pncA	2290015	c.-774A>C	upstream_gene_variant	0.94	pyrazinamide
pncA	2290024	c.-783C>G	upstream_gene_variant	0.94	pyrazinamide
pncA	2290030	c.-791_-789delAATinsCAC	upstream_gene_variant	0.93	pyrazinamide
pncA	2290033	c.-792C>G	upstream_gene_variant	0.93	pyrazinamide
pncA	2290038	c.-797G>A	upstream_gene_variant	0.93	pyrazinamide
pncA	2290042	c.-801T>C	upstream_gene_variant	0.93	pyrazinamide
pncA	2290069	c.-830_-828delAGCinsGGA	upstream_gene_variant	0.92	pyrazinamide
pncA	2290072	c.-831T>C	upstream_gene_variant	0.91	pyrazinamide
pncA	2290075	c.-834C>G	upstream_gene_variant	0.91	pyrazinamide
kasA	2517941	c.-174C>G	upstream_gene_variant	0.73	isoniazid
kasA	2517950	c.-165C>G	upstream_gene_variant	1.0	isoniazid
kasA	2517962	c.-153C>G	upstream_gene_variant	0.76	isoniazid
kasA	2517965	c.-150C>T	upstream_gene_variant	0.75	isoniazid
kasA	2517974	c.-141T>C	upstream_gene_variant	0.75	isoniazid
kasA	2517983	c.-132T>C	upstream_gene_variant	0.82	isoniazid
kasA	2517989	c.-126T>G	upstream_gene_variant	0.92	isoniazid
kasA	2517993	c.-122G>T	upstream_gene_variant	1.0	isoniazid
kasA	2518019	c.-96A>G	upstream_gene_variant	1.0	isoniazid
kasA	2518025	c.-90G>C	upstream_gene_variant	1.0	isoniazid
kasA	2518031	c.-84G>T	upstream_gene_variant	1.0	isoniazid
kasA	2518528	c.414C>G	synonymous_variant	1.0	isoniazid
kasA	2518636	c.522C>A	synonymous_variant	0.71	isoniazid
kasA	2518639	c.525G>C	synonymous_variant	1.0	isoniazid
kasA	2518642	c.528A>G	synonymous_variant	0.71	isoniazid
kasA	2518645	c.531G>C	synonymous_variant	0.71	isoniazid
kasA	2518651	c.537C>G	synonymous_variant	0.71	isoniazid
kasA	2518657	c.543G>C	synonymous_variant	1.0	isoniazid
kasA	2518663	c.549T>C	synonymous_variant	0.67	isoniazid
kasA	2518672	c.558G>C	synonymous_variant	1.0	isoniazid
kasA	2518678	c.564C>T	synonymous_variant	1.0	isoniazid
kasA	2518684	c.570C>G	synonymous_variant	1.0	isoniazid
kasA	2518693	c.579C>G	synonymous_variant	1.0	isoniazid
kasA	2518702	c.588C>T	synonymous_variant	1.0	isoniazid
kasA	2518705	c.591T>C	synonymous_variant	0.46	isoniazid
kasA	2518711	c.597A>G	synonymous_variant	1.0	isoniazid
kasA	2518714	c.600A>C	synonymous_variant	1.0	isoniazid
kasA	2518747	c.633C>G	synonymous_variant	1.0	isoniazid
kasA	2518825	c.711T>C	synonymous_variant	1.0	isoniazid
kasA	2518840	c.726C>G	synonymous_variant	0.67	isoniazid
kasA	2518843	c.729T>G	synonymous_variant	0.67	isoniazid
kasA	2518846	c.732G>C	synonymous_variant	0.67	isoniazid
kasA	2518855	c.741C>G	synonymous_variant	0.73	isoniazid
kasA	2518864	c.750G>C	synonymous_variant	1.0	isoniazid
Rv2477c	2783502	c.541T>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783512	c.531A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783520	c.523T>C	synonymous_variant	0.56	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2477c	2783521	c.522G>C	synonymous_variant	0.56	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783527	c.516A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783539	c.504G>C	synonymous_variant	0.53	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783554	c.489C>T	synonymous_variant	0.47	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783557	c.486T>C	synonymous_variant	0.5	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783563	c.480A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783572	c.471A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783578	c.465G>A	synonymous_variant	0.44	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783586	p.Ala153Pro	missense_variant	0.58	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783593	c.450T>C	synonymous_variant	0.54	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783602	c.441G>A	synonymous_variant	0.46	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783605	c.438T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783620	c.423C>G	synonymous_variant	0.58	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783623	c.420G>A	synonymous_variant	0.42	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783628	p.Ala139Ser	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783632	c.411C>G	synonymous_variant	0.38	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783656	c.387G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783665	c.378A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783674	c.369T>C	synonymous_variant	0.64	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783683	c.360A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783700	p.Thr115Ser	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783718	c.325T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783719	c.324A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783751	p.Ile98Val	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783758	p.Asp95Glu	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783761	c.282G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783776	c.267G>C	synonymous_variant	0.52	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783779	c.264T>C	synonymous_variant	0.45	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783788	c.255T>G	synonymous_variant	0.54	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783794	c.249G>A	synonymous_variant	0.53	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783797	p.Asp82Glu	missense_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783806	c.237G>C	synonymous_variant	0.51	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783815	c.228A>G	synonymous_variant	0.47	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783821	p.Gln74Leu	missense_variant	0.97	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783827	c.216C>T	synonymous_variant	0.44	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783833	c.210G>C	synonymous_variant	0.97	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783836	c.207C>G	synonymous_variant	0.5	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783839	c.204C>G	synonymous_variant	0.48	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783843	p.Gly67Asp	missense_variant	0.97	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783846	p.Thr66Asn	missense_variant	0.97	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783857	c.186C>G	synonymous_variant	0.46	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783860	c.183T>C	synonymous_variant	0.97	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783863	c.180C>T	synonymous_variant	0.51	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783881	c.160_162delTTGinsCTC	synonymous_variant	0.49	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783884	c.159T>G	synonymous_variant	0.95	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783887	c.156C>G	synonymous_variant	0.47	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783914	c.129T>C	synonymous_variant	0.44	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783920	c.123G>T	synonymous_variant	0.5	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2477c	2783920	c.123G>C	synonymous_variant	0.48	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783929	c.114C>G	synonymous_variant	0.45	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783932	c.111C>T	synonymous_variant	0.5	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783938	c.105T>C	synonymous_variant	0.97	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783953	c.90G>A	synonymous_variant	0.55	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783956	p.Tyr29Phe	missense_variant	0.47	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783962	c.81T>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783968	c.75G>C	synonymous_variant	0.48	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783971	c.72G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783980	c.63C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783992	c.51T>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
pepQ	2859791	p.Ala210Ser	missense_variant	0.82	bedaquiline
pepQ	2859791	p.Ala210Ser	missense_variant	0.82	clofazimine
pepQ	2859824	p.Asn199His	missense_variant	0.92	bedaquiline
pepQ	2859824	p.Asn199His	missense_variant	0.92	clofazimine
pepQ	2859825	p.Ala198Pro	missense_variant	0.86	bedaquiline
pepQ	2859825	p.Ala198Pro	missense_variant	0.86	clofazimine
pepQ	2859828	c.591G>A	synonymous_variant	0.86	bedaquiline
pepQ	2859828	c.591G>A	synonymous_variant	0.86	clofazimine
pepQ	2859833	p.Ala196Ser	missense_variant	0.92	bedaquiline
pepQ	2859833	p.Ala196Ser	missense_variant	0.92	clofazimine
pepQ	2859834	c.585T>G	synonymous_variant	0.92	bedaquiline
pepQ	2859834	c.585T>G	synonymous_variant	0.92	clofazimine
Rv2752c	3065040	c.1150_1152delCTCinsTTG	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065049	c.1143G>A	synonymous_variant	0.64	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065055	c.1137T>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065064	c.1128G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065070	c.1122C>A	synonymous_variant	0.79	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065073	c.1119C>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065085	c.1105_1107delAGGinsCGC	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065088	c.1104A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
					moxifloxacin
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065097	c.1095C>T	synonymous_variant	0.71	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065106	c.1086C>G	synonymous_variant	0.71	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065109	c.1081_1083delAGAinsCGG	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065130	c.1062A>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065133	c.1059T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065142	c.1050A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065146	p.Phe349Tyr	missense_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065154	c.1038G>A	synonymous_variant	0.64	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065174	c.1018C>T	synonymous_variant	0.65	levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
Rv2752c	3065186	c.1006T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065190	p.Ile334Val	missense_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065199	c.993T>C	synonymous_variant	0.65	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065202	c.990T>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065205	c.987T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065210	c.982T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065223	c.969T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065229	c.963G>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065232	c.960T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065235	c.957G>C	synonymous_variant	0.57	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065241	c.951A>G	synonymous_variant	0.93	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065262	c.930G>A	synonymous_variant	0.58	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065268	c.924A>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065979	c.213T>C	synonymous_variant	0.92	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3065993	p.Val67Ile	missense_variant	0.92	levofloxacin
					moxifloxacin
					isoniazid	Uncertain significance
					rifampicin	Uncertain significance
					ethambutol	Uncertain significance
Rv2752c	3065994	c.198T>C	synonymous_variant	0.92	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066002	p.Met64Leu	missense_variant	0.9	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066009	c.183G>C	synonymous_variant	0.69	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066018	c.174T>C	synonymous_variant	0.69	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066501	c.-310G>C	upstream_gene_variant	0.73	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066522	c.-331C>G	upstream_gene_variant	0.77	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066531	c.-340C>G	upstream_gene_variant	0.71	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066549	c.-358T>C	upstream_gene_variant	0.83	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066561	c.-370A>G	upstream_gene_variant	0.6	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066573	c.-382G>C	upstream_gene_variant	0.93	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066579	c.-388A>G	upstream_gene_variant	0.94	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066583	c.-392C>G	upstream_gene_variant	0.95	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066603	c.-412A>G	upstream_gene_variant	0.95	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066617	c.-426G>A	upstream_gene_variant	0.95	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066618	c.-427A>G	upstream_gene_variant	0.95	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066633	c.-442T>C	upstream_gene_variant	0.94	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066638	c.-447T>G	upstream_gene_variant	0.57	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066839	c.-648A>G	upstream_gene_variant	0.75	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
Rv2752c	3066855	c.-664T>C	upstream_gene_variant	0.91	levofloxacin
					moxifloxacin
					isoniazid
					rifampicin
					ethambutol
thyX	3067274	c.672C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067277	c.669C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067281	p.Val222Ala	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067284	p.Ala221Gly	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067286	c.660C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067289	c.657C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067292	c.654G>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067295	c.651C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067316	c.630A>G	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067325	c.621A>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyX	3067328	c.618G>A	synonymous_variant	0.79	para-aminosalicylic_acid
thyX	3067349	c.597G>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067355	c.591A>C	synonymous_variant	0.9	para-aminosalicylic_acid
thyX	3067367	c.579G>C	synonymous_variant	0.66	para-aminosalicylic_acid
thyX	3067373	c.573C>G	synonymous_variant	0.66	para-aminosalicylic_acid
thyX	3067391	c.555G>C	synonymous_variant	0.68	para-aminosalicylic_acid
thyX	3067394	c.552G>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067439	c.507A>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067445	c.501C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067457	c.489C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067465	p.Ile161Val	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067466	c.480G>C	synonymous_variant	0.79	para-aminosalicylic_acid
thyX	3067475	c.471A>G	synonymous_variant	0.82	para-aminosalicylic_acid
thyX	3067490	c.456C>G	synonymous_variant	0.86	para-aminosalicylic_acid
thyX	3067493	c.453A>G	synonymous_variant	0.86	para-aminosalicylic_acid
thyX	3067515	p.Ser144Thr	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067530	p.Ala139Ser	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067545	p.Glu134Ala	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067549	p.Thr133Ala	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067556	p.His130Gln	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067559	c.387C>G	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067565	p.Asp127Glu	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067570	p.Ala126Pro	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067577	c.369G>A	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067601	p.Arg115His	missense_variant	0.9	para-aminosalicylic_acid
thyX	3067611	p.Lys112Thr	missense_variant	0.95	para-aminosalicylic_acid
thyX	3067619	c.327A>C	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067631	c.315C>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067634	c.312C>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067652	c.294T>C	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067661	c.285C>G	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067685	c.261A>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067691	p.Ile85Leu	missense_variant	1.0	para-aminosalicylic_acid
thyX	3067694	c.252G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067718	c.228C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067721	c.225T>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067727	c.219A>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067736	p.Phe70Leu	missense_variant	0.88	para-aminosalicylic_acid
thyX	3067739	c.207T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyX	3067761	p.Arg62Lys	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067765	p.Leu61Ile	missense_variant	0.96	para-aminosalicylic_acid
thyX	3067772	c.174C>G	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067781	c.165C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067793	c.153T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067799	c.147G>A	synonymous_variant	0.87	para-aminosalicylic_acid
thyX	3067802	c.144C>G	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067814	c.132T>C	synonymous_variant	0.97	para-aminosalicylic_acid
thyX	3067850	c.96A>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067869	p.Thr26Ser	missense_variant	0.95	para-aminosalicylic_acid
thyX	3067874	c.72C>G	synonymous_variant	0.9	para-aminosalicylic_acid
thyX	3067883	c.63C>G	synonymous_variant	0.9	para-aminosalicylic_acid
thyX	3067886	c.60A>C	synonymous_variant	0.94	para-aminosalicylic_acid
thyX	3067889	c.57C>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067898	p.Asp16Glu	missense_variant	1.0	para-aminosalicylic_acid
thyA	3073944	c.528C>T	synonymous_variant	0.92	para-aminosalicylic_acid
thyA	3073953	c.519T>C	synonymous_variant	0.92	para-aminosalicylic_acid
thyA	3073956	c.516G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073959	c.513T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073968	c.504C>G	synonymous_variant	0.85	para-aminosalicylic_acid
thyA	3073977	c.495A>G	synonymous_variant	0.93	para-aminosalicylic_acid
thyA	3073989	c.483T>C	synonymous_variant	0.93	para-aminosalicylic_acid
thyA	3074001	c.471C>G	synonymous_variant	0.62	para-aminosalicylic_acid
thyA	3074004	c.468T>C	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074037	c.435C>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3074053	p.Arg140Gln	missense_variant	0.93	para-aminosalicylic_acid
mtrB	3625636	p.Ala326Glu	missense_variant	0.91	rifampicin
mtrB	3625636	p.Ala326Glu	missense_variant	0.91	bedaquiline
mtrB	3625656	c.958T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrB	3625656	c.958T>C	synonymous_variant	0.92	bedaquiline	Not assoc w R - Interim
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.93	rifampicin
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.93	bedaquiline
lpqB	3625687	c.-777G>C	upstream_gene_variant	1.0	rifampicin
lpqB	3625687	c.-777G>C	upstream_gene_variant	1.0	bedaquiline
lpqB	3625696	c.-786A>G	upstream_gene_variant	1.0	rifampicin
lpqB	3625696	c.-786A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3625699	c.915C>T	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
mtrB	3625699	c.915C>T	synonymous_variant	0.81	bedaquiline
lpqB	3625717	c.-807C>T	upstream_gene_variant	0.9	rifampicin
lpqB	3625717	c.-807C>T	upstream_gene_variant	0.9	bedaquiline
mtrB	3625747	c.867G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
mtrB	3625747	c.867G>C	synonymous_variant	0.85	bedaquiline
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.82	rifampicin
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.82	bedaquiline
mtrB	3625765	c.849C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3625765	c.849C>G	synonymous_variant	0.96	bedaquiline
lpqB	3625783	c.-873C>T	upstream_gene_variant	0.75	rifampicin
lpqB	3625783	c.-873C>T	upstream_gene_variant	0.75	bedaquiline
lpqB	3625801	c.-891G>C	upstream_gene_variant	0.72	rifampicin
lpqB	3625801	c.-891G>C	upstream_gene_variant	0.72	bedaquiline
mtrB	3625806	c.808A>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrB	3625806	c.808A>C	synonymous_variant	0.92	bedaquiline
lpqB	3625849	c.-939T>C	upstream_gene_variant	0.8	rifampicin
lpqB	3625849	c.-939T>C	upstream_gene_variant	0.8	bedaquiline
mtrB	3625852	c.762A>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
mtrB	3625852	c.762A>G	synonymous_variant	0.88	bedaquiline
lpqB	3625864	c.-954T>G	upstream_gene_variant	0.77	rifampicin
lpqB	3625864	c.-954T>G	upstream_gene_variant	0.77	bedaquiline
mtrB	3625876	c.738G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
mtrB	3625876	c.738G>C	synonymous_variant	0.92	bedaquiline
mtrA	3626759	c.591T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrA	3626759	c.591T>C	synonymous_variant	0.96	bedaquiline
mtrB	3626774	c.-163_-161delAGGinsCGC	upstream_gene_variant	0.96	rifampicin
mtrB	3626774	c.-163_-161delAGGinsCGC	upstream_gene_variant	0.96	bedaquiline
mtrB	3626783	c.-170C>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626783	c.-170C>G	upstream_gene_variant	0.95	bedaquiline
mtrA	3626786	c.564A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrA	3626786	c.564A>G	synonymous_variant	0.96	bedaquiline
mtrA	3626792	c.558G>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrA	3626792	c.558G>T	synonymous_variant	0.96	bedaquiline
mtrB	3626795	c.-182C>T	upstream_gene_variant	0.65	rifampicin
mtrB	3626795	c.-182C>T	upstream_gene_variant	0.65	bedaquiline
mtrB	3626798	c.-185T>C	upstream_gene_variant	0.94	rifampicin
mtrB	3626798	c.-185T>C	upstream_gene_variant	0.94	bedaquiline
mtrA	3626804	c.546A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrA	3626804	c.546A>G	synonymous_variant	0.96	bedaquiline
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.59	rifampicin
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.59	bedaquiline
mtrA	3626846	c.504G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626846	c.504G>A	synonymous_variant	1.0	bedaquiline
mtrB	3626858	c.-245A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626858	c.-245A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626861	c.-248C>G	upstream_gene_variant	0.57	rifampicin
mtrB	3626861	c.-248C>G	upstream_gene_variant	0.57	bedaquiline
mtrB	3626866	c.-253T>C	upstream_gene_variant	0.59	rifampicin
mtrB	3626866	c.-253T>C	upstream_gene_variant	0.59	bedaquiline
mtrB	3626876	c.-263A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626876	c.-263A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626885	c.-272A>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626885	c.-272A>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626890	c.-277T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626890	c.-277T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626903	c.-290T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626903	c.-290T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626912	c.-299T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626912	c.-299T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626927	c.-314G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626927	c.-314G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626930	c.-317A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626930	c.-317A>G	upstream_gene_variant	1.0	bedaquiline
mtrA	3626939	c.411A>G	synonymous_variant	0.59	rifampicin	Not assoc w R - Interim
mtrA	3626939	c.411A>G	synonymous_variant	0.59	bedaquiline
mtrB	3626942	c.-329A>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626942	c.-329A>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.36	rifampicin
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.36	bedaquiline
mtrB	3626957	c.-344G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626957	c.-344G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3626972	c.-359A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626972	c.-359A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626987	c.-374C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626987	c.-374C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3626996	c.-383G>A	upstream_gene_variant	0.38	rifampicin
mtrB	3626996	c.-383G>A	upstream_gene_variant	0.38	bedaquiline
mtrB	3627008	c.-395G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627008	c.-395G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627011	c.-398T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627011	c.-398T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627023	c.-410C>G	upstream_gene_variant	0.38	rifampicin
mtrB	3627023	c.-410C>G	upstream_gene_variant	0.38	bedaquiline
mtrB	3627059	c.-446G>C	upstream_gene_variant	0.48	rifampicin
mtrB	3627059	c.-446G>C	upstream_gene_variant	0.48	bedaquiline
mtrB	3627065	c.-452G>C	upstream_gene_variant	0.55	rifampicin
mtrB	3627065	c.-452G>C	upstream_gene_variant	0.55	bedaquiline
mtrA	3627068	c.282T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627068	c.282T>C	synonymous_variant	1.0	bedaquiline
mtrA	3627071	c.279G>T	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
mtrA	3627071	c.279G>T	synonymous_variant	0.48	bedaquiline
mtrB	3627074	c.-461G>C	upstream_gene_variant	0.48	rifampicin
mtrB	3627074	c.-461G>C	upstream_gene_variant	0.48	bedaquiline
mtrA	3627080	c.270T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627080	c.270T>C	synonymous_variant	1.0	bedaquiline
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.52	rifampicin
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.52	bedaquiline
mtrA	3627098	c.252A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627098	c.252A>C	synonymous_variant	1.0	bedaquiline
mtrB	3627104	c.-491C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627104	c.-491C>G	upstream_gene_variant	1.0	bedaquiline
mtrA	3627119	c.231T>G	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
mtrA	3627119	c.231T>G	synonymous_variant	0.56	bedaquiline
mtrB	3627122	c.-509T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627122	c.-509T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627167	c.-554T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627167	c.-554T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627181	c.-568T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627181	c.-568T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627182	c.-569T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627182	c.-569T>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627188	c.162A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627188	c.162A>G	synonymous_variant	1.0	bedaquiline
mtrB	3627209	c.-596G>A	upstream_gene_variant	0.95	rifampicin
mtrB	3627209	c.-596G>A	upstream_gene_variant	0.95	bedaquiline
mtrA	3627221	c.129C>T	synonymous_variant	0.58	rifampicin	Not assoc w R - Interim
mtrA	3627221	c.129C>T	synonymous_variant	0.58	bedaquiline
mtrA	3627227	c.123T>C	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
mtrA	3627227	c.123T>C	synonymous_variant	0.56	bedaquiline
mtrB	3627233	c.-620T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627233	c.-620T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627236	c.-623T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627236	c.-623T>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627239	c.111C>T	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
mtrA	3627239	c.111C>T	synonymous_variant	0.48	bedaquiline	Not assoc w R - Interim
mtrA	3627242	c.108C>T	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
mtrA	3627242	c.108C>T	synonymous_variant	0.48	bedaquiline
mtrB	3627254	c.-641C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627254	c.-641C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627263	c.-650C>T	upstream_gene_variant	0.44	rifampicin
mtrB	3627263	c.-650C>T	upstream_gene_variant	0.44	bedaquiline
mtrB	3627266	c.-653A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627266	c.-653A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627272	c.-659G>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627272	c.-659G>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627275	c.-662G>T	upstream_gene_variant	0.48	rifampicin
mtrB	3627275	c.-662G>T	upstream_gene_variant	0.48	bedaquiline
mtrB	3627278	c.-665G>T	upstream_gene_variant	0.52	rifampicin
mtrB	3627278	c.-665G>T	upstream_gene_variant	0.52	bedaquiline
mtrB	3627287	c.-674C>G	upstream_gene_variant	0.52	rifampicin
mtrB	3627287	c.-674C>G	upstream_gene_variant	0.52	bedaquiline
mtrB	3627296	c.-683T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627296	c.-683T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627299	c.-688_-686delTTGinsCTA	upstream_gene_variant	1.0	rifampicin
mtrB	3627299	c.-688_-686delTTGinsCTA	upstream_gene_variant	1.0	bedaquiline
mtrB	3627314	c.-701C>T	upstream_gene_variant	0.48	rifampicin
mtrB	3627314	c.-701C>T	upstream_gene_variant	0.48	bedaquiline
mtrB	3627317	c.-704T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627317	c.-704T>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627343	p.Thr3Ser	missense_variant	1.0	rifampicin
mtrA	3627343	p.Thr3Ser	missense_variant	1.0	bedaquiline
fbiB	3641586	p.Ile18Ala	missense_variant	0.9	pretomanid
					delamanid
					clofazimine
alr	3840542	c.879G>A	synonymous_variant	1.0	cycloserine
alr	3840548	c.873G>A	synonymous_variant	1.0	cycloserine
alr	3840551	c.870G>T	synonymous_variant	1.0	cycloserine
alr	3840554	c.867G>C	synonymous_variant	1.0	cycloserine
alr	3840562	p.Ile287Val	missense_variant	1.0	cycloserine
alr	3840566	c.855A>G	synonymous_variant	1.0	cycloserine
alr	3840574	c.847C>T	synonymous_variant	1.0	cycloserine
alr	3840578	c.843T>G	synonymous_variant	1.0	cycloserine
alr	3840599	c.822G>C	synonymous_variant	1.0	cycloserine
rpoA	3877515	c.993G>C	synonymous_variant	1.0	rifampicin
rpoA	3877557	c.951C>G	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
rpoA	3877587	c.921A>C	synonymous_variant	1.0	rifampicin
rpoA	3877613	p.Ile299Val	missense_variant	1.0	rifampicin
rpoA	3877617	c.891G>C	synonymous_variant	0.62	rifampicin
rpoA	3877638	c.870T>G	synonymous_variant	0.57	rifampicin
rpoA	3877656	c.852T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877668	c.840A>G	synonymous_variant	0.48	rifampicin
rpoA	3877677	p.Ala277Cys	missense_variant	0.48	rifampicin
rpoA	3877680	c.828G>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoA	3877685	c.823C>T	synonymous_variant	0.5	rifampicin
rpoA	3877686	c.822A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877692	c.816G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877704	c.804G>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoA	3877737	c.771G>C	synonymous_variant	0.64	rifampicin
rpoA	3877743	c.765T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877758	c.750G>C	synonymous_variant	0.56	rifampicin
rpoA	3877764	c.744C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877770	c.738A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877776	c.732T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877782	c.726T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877791	c.717C>G	synonymous_variant	0.42	rifampicin
rpoA	3877815	c.693C>T	synonymous_variant	0.58	rifampicin	Not assoc w R - Interim
rpoA	3877818	c.690A>G	synonymous_variant	0.43	rifampicin	Not assoc w R - Interim
rpoA	3877839	c.669G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877851	c.657C>T	synonymous_variant	0.53	rifampicin
rpoA	3877857	c.651G>A	synonymous_variant	1.0	rifampicin
rpoA	3877865	c.643C>T	synonymous_variant	0.48	rifampicin
rpoA	3877866	c.642G>C	synonymous_variant	1.0	rifampicin
rpoA	3877872	c.636C>T	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
rpoA	3877875	c.633T>G	synonymous_variant	1.0	rifampicin
rpoA	3877887	c.621G>C	synonymous_variant	0.52	rifampicin
rpoA	3877900	p.Ser203Thr	missense_variant	0.9	rifampicin
rpoA	3877905	c.603A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877908	p.Asn200Ser	missense_variant	0.53	rifampicin
rpoA	3877920	c.588G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877962	c.546G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877968	c.540C>G	synonymous_variant	0.69	rifampicin
rpoA	3877989	c.519A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878001	c.507A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878022	c.486T>C	synonymous_variant	1.0	rifampicin
rpoA	3878025	c.483C>T	synonymous_variant	0.72	rifampicin
rpoA	3878028	c.480G>C	synonymous_variant	1.0	rifampicin
rpoA	3878031	c.477T>C	synonymous_variant	1.0	rifampicin
rpoA	3878043	c.465G>C	synonymous_variant	1.0	rifampicin
rpoA	3878046	c.462T>G	synonymous_variant	0.71	rifampicin
rpoA	3878055	c.453A>G	synonymous_variant	1.0	rifampicin
rpoA	3878061	c.447G>C	synonymous_variant	1.0	rifampicin
rpoA	3878067	c.441C>G	synonymous_variant	1.0	rifampicin
rpoA	3878070	c.438T>C	synonymous_variant	1.0	rifampicin
rpoA	3878082	c.426T>C	synonymous_variant	0.6	rifampicin
rpoA	3878094	c.414C>G	synonymous_variant	0.41	rifampicin
rpoA	3878097	c.411G>A	synonymous_variant	0.57	rifampicin
rpoA	3878103	c.405A>G	synonymous_variant	1.0	rifampicin
rpoA	3878106	c.402G>C	synonymous_variant	1.0	rifampicin
rpoA	3878118	c.390T>C	synonymous_variant	1.0	rifampicin
rpoA	3878130	c.378C>G	synonymous_variant	1.0	rifampicin
rpoA	3878169	c.339G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878187	c.321C>G	synonymous_variant	1.0	rifampicin
rpoA	3878193	c.315T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878217	c.291A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878226	c.282C>G	synonymous_variant	0.55	rifampicin
rpoA	3878247	c.261G>C	synonymous_variant	0.96	rifampicin
rpoA	3878271	c.237T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878292	c.216T>C	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoA	3878295	c.213A>G	synonymous_variant	0.41	rifampicin
rpoA	3878298	c.210A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3878304	c.204G>C	synonymous_variant	0.97	rifampicin
rpoA	3878313	c.195G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3878322	c.186A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3878331	c.177A>C	synonymous_variant	0.97	rifampicin
rpoA	3878334	c.174T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3878337	c.171T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3878340	c.168C>T	synonymous_variant	0.32	rifampicin
rpoA	3878346	c.162T>C	synonymous_variant	0.96	rifampicin
rpoA	3878364	c.144A>C	synonymous_variant	0.97	rifampicin
rpoA	3878370	c.138T>C	synonymous_variant	0.68	rifampicin
rpoA	3878376	c.132G>C	synonymous_variant	0.98	rifampicin
rpoA	3878384	c.124C>T	synonymous_variant	0.67	rifampicin
rpoA	3878385	c.123C>G	synonymous_variant	0.98	rifampicin
rpoA	3878391	c.117T>G	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoA	3878418	c.90C>T	synonymous_variant	0.74	rifampicin
rpoA	3878442	c.66G>C	synonymous_variant	0.97	rifampicin
rpoA	3878454	c.54A>G	synonymous_variant	0.96	rifampicin
rpoA	3878458	p.Asn17Ser	missense_variant	0.78	rifampicin
rpoA	3878471	p.Val13Leu	missense_variant	0.62	rifampicin
rpoA	3878472	p.Asp12Glu	missense_variant	0.88	rifampicin
rpoA	3878484	c.24C>A	synonymous_variant	0.87	rifampicin
rpoA	3878490	c.18C>A	synonymous_variant	0.92	rifampicin
rpoA	3878496	c.12A>T	synonymous_variant	1.0	rifampicin
rpoA	3878742	c.-235G>A	upstream_gene_variant	0.8	rifampicin
rpoA	3878746	c.-239A>G	upstream_gene_variant	0.8	rifampicin	Uncertain significance
rpoA	3878761	c.-254G>A	upstream_gene_variant	0.64	rifampicin	Uncertain significance
rpoA	3878764	c.-257A>G	upstream_gene_variant	0.86	rifampicin
rpoA	3878776	c.-269G>C	upstream_gene_variant	0.53	rifampicin
rpoA	3878779	c.-274_-272delATCinsGTT	upstream_gene_variant	0.53	rifampicin
rpoA	3878788	c.-281G>T	upstream_gene_variant	0.75	rifampicin
rpoA	3878803	c.-296G>C	upstream_gene_variant	0.5	rifampicin	Uncertain significance
rpoA	3878809	c.-302T>C	upstream_gene_variant	0.86	rifampicin
rpoA	3878824	c.-317G>C	upstream_gene_variant	0.86	rifampicin
rpoA	3878833	c.-326C>G	upstream_gene_variant	0.86	rifampicin
rpoA	3878836	c.-330_-329delAGinsCC	upstream_gene_variant	0.86	rifampicin
rpoA	3878842	c.-335G>C	upstream_gene_variant	0.57	rifampicin
rpoA	3878853	c.-346G>A	upstream_gene_variant	0.91	rifampicin
rpoA	3878869	c.-362G>C	upstream_gene_variant	0.59	rifampicin
rpoA	3878878	c.-371T>C	upstream_gene_variant	0.82	rifampicin	Uncertain significance
rpoA	3878881	c.-374C>G	upstream_gene_variant	0.47	rifampicin
rpoA	3878914	c.-407T>C	upstream_gene_variant	0.92	rifampicin	Uncertain significance
rpoA	3878923	c.-417_-416delGCinsCG	upstream_gene_variant	0.64	rifampicin
rpoA	3878947	c.-440G>C	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878953	c.-446C>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878962	c.-455G>A	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878968	c.-461T>C	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878974	c.-469_-467delATCinsGTG	upstream_gene_variant	1.0	rifampicin
rpoA	3878995	c.-488A>G	upstream_gene_variant	0.61	rifampicin
rpoA	3878998	c.-491C>G	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3879001	c.-494C>T	upstream_gene_variant	0.61	rifampicin
rpoA	3879004	c.-499_-497delAAGinsCGC	upstream_gene_variant	0.61	rifampicin
rpoA	3879013	c.-506A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879016	c.-509A>G	upstream_gene_variant	0.6	rifampicin
rpoA	3879022	c.-515G>C	upstream_gene_variant	0.62	rifampicin
rpoA	3879037	c.-530G>A	upstream_gene_variant	0.58	rifampicin
rpoA	3879049	c.-542A>G	upstream_gene_variant	0.52	rifampicin
rpoA	3879079	c.-572A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879088	c.-581A>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879094	c.-587T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879117	c.-610C>T	upstream_gene_variant	0.41	rifampicin
rpoA	3879121	c.-614T>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879127	c.-620T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879145	c.-638G>C	upstream_gene_variant	0.4	rifampicin
rpoA	3879148	c.-641G>C	upstream_gene_variant	0.4	rifampicin
rpoA	3879154	c.-647T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879160	c.-653A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879190	c.-683C>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879202	c.-695T>C	upstream_gene_variant	0.38	rifampicin
rpoA	3879208	c.-701C>G	upstream_gene_variant	0.35	rifampicin
rpoA	3879222	c.-715T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879226	c.-719G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3879229	c.-722A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3879232	c.-725A>G	upstream_gene_variant	1.0	rifampicin
clpC1	4038239	c.2466T>C	synonymous_variant	0.8	pyrazinamide
clpC1	4038255	p.Val817Lys	missense_variant	0.67	pyrazinamide
clpC1	4038271	p.Pro812Ala	missense_variant	0.92	pyrazinamide
clpC1	4038272	p.Gly811Ser	missense_variant	0.92	pyrazinamide
clpC1	4038275	c.2430A>G	synonymous_variant	0.67	pyrazinamide
clpC1	4038278	c.2427T>C	synonymous_variant	0.92	pyrazinamide
clpC1	4038293	c.2412G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4038302	c.2403C>G	synonymous_variant	0.9	pyrazinamide
clpC1	4038308	c.2397G>T	synonymous_variant	0.69	pyrazinamide
clpC1	4038314	c.2391T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4038317	c.2388G>C	synonymous_variant	0.87	pyrazinamide
clpC1	4038320	c.2385G>C	synonymous_variant	0.87	pyrazinamide
clpC1	4038347	c.2358G>C	synonymous_variant	0.37	pyrazinamide
clpC1	4038356	c.2349T>C	synonymous_variant	0.82	pyrazinamide
clpC1	4038359	c.2346A>G	synonymous_variant	0.89	pyrazinamide
clpC1	4038368	c.2337T>C	synonymous_variant	0.9	pyrazinamide
clpC1	4038388	c.2317T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4038392	c.2313C>T	synonymous_variant	0.48	pyrazinamide
clpC1	4038398	c.2307G>T	synonymous_variant	0.96	pyrazinamide
clpC1	4038403	c.2302T>C	synonymous_variant	0.96	pyrazinamide	Not assoc w R - Interim
clpC1	4038407	c.2298G>C	synonymous_variant	0.43	pyrazinamide
clpC1	4038419	c.2286T>C	synonymous_variant	0.4	pyrazinamide
clpC1	4038425	c.2280C>A	synonymous_variant	0.58	pyrazinamide
clpC1	4038434	c.2271G>A	synonymous_variant	0.36	pyrazinamide
clpC1	4038444	p.Ala754Lys	missense_variant	0.96	pyrazinamide
clpC1	4038446	c.2259T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038456	p.Val750Glu	missense_variant	0.96	pyrazinamide
clpC1	4038486	p.Gly740Asn	missense_variant	1.0	pyrazinamide
clpC1	4038491	c.2214C>T	synonymous_variant	0.8	pyrazinamide
clpC1	4038502	p.Ile735Val	missense_variant	0.79	pyrazinamide
clpC1	4038508	c.2197C>T	synonymous_variant	0.78	pyrazinamide
clpC1	4038518	c.2187G>T	synonymous_variant	0.78	pyrazinamide
clpC1	4038530	p.Glu725Asp	missense_variant	1.0	pyrazinamide
clpC1	4038537	p.Thr723Ser	missense_variant	0.87	pyrazinamide
clpC1	4038539	c.2166G>C	synonymous_variant	0.87	pyrazinamide
clpC1	4038569	c.2136C>T	synonymous_variant	0.64	pyrazinamide
clpC1	4038575	c.2130C>G	synonymous_variant	0.54	pyrazinamide
clpC1	4038596	c.2109A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038623	c.2082A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038640	p.Asp689Asn	missense_variant	0.54	pyrazinamide
clpC1	4038653	c.2052C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038658	p.Lys683Gln	missense_variant	1.0	pyrazinamide
clpC1	4038661	p.Ser682Thr	missense_variant	1.0	pyrazinamide
clpC1	4038662	c.2043T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038668	c.2037G>C	synonymous_variant	0.41	pyrazinamide
clpC1	4038671	c.2034T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038677	c.2028G>C	synonymous_variant	0.41	pyrazinamide
clpC1	4038683	c.2022T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038692	c.2013C>G	synonymous_variant	0.42	pyrazinamide	Not assoc w R - Interim
clpC1	4038695	c.2010C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038698	c.2007C>T	synonymous_variant	0.46	pyrazinamide	Not assoc w R - Interim
clpC1	4038701	c.2004G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038704	c.2001T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038707	c.1998C>G	synonymous_variant	0.5	pyrazinamide
clpC1	4038710	c.1995G>C	synonymous_variant	0.48	pyrazinamide
clpC1	4038713	c.1992T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038740	c.1965G>C	synonymous_variant	0.63	pyrazinamide
clpC1	4038749	c.1956C>T	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038755	c.1950G>T	synonymous_variant	0.43	pyrazinamide
clpC1	4038770	c.1935C>T	synonymous_variant	0.46	pyrazinamide
clpC1	4038773	c.1932T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038782	c.1923G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038790	c.1915C>T	synonymous_variant	0.48	pyrazinamide	Not assoc w R - Interim
clpC1	4038809	c.1896G>A	synonymous_variant	0.47	pyrazinamide
clpC1	4038812	c.1893T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038845	c.1860G>C	synonymous_variant	0.48	pyrazinamide
clpC1	4038860	c.1845G>C	synonymous_variant	0.5	pyrazinamide	Not assoc w R - Interim
clpC1	4038875	c.1830C>G	synonymous_variant	0.43	pyrazinamide
clpC1	4038878	c.1827A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038893	c.1812C>T	synonymous_variant	0.41	pyrazinamide
clpC1	4038908	c.1797C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038914	c.1791G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038923	c.1780_1782delCTAinsTTG	synonymous_variant	1.0	pyrazinamide
clpC1	4038953	c.1752A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038956	c.1749T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038965	c.1740T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038971	c.1734T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038974	c.1731T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038989	c.1716T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038997	c.1708T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039004	c.1701C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039022	c.1683A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039064	c.1641C>T	synonymous_variant	0.78	pyrazinamide
clpC1	4039097	c.1608G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039103	c.1602T>C	synonymous_variant	0.65	pyrazinamide
clpC1	4039106	c.1599G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039112	c.1593C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039121	c.1584T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039142	c.1563A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039145	c.1560G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039169	p.Glu512Asp	missense_variant	1.0	pyrazinamide
clpC1	4039172	c.1533A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039178	c.1527G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039223	c.1482C>T	synonymous_variant	0.62	pyrazinamide
clpC1	4039226	c.1479T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039274	c.1431G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039286	c.1419T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039295	c.1410A>C	synonymous_variant	0.57	pyrazinamide
clpC1	4039298	c.1407T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039319	p.Ala462Thr	missense_variant	1.0	pyrazinamide
clpC1	4039322	c.1383T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039328	c.1377A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039331	c.1374C>G	synonymous_variant	0.58	pyrazinamide
clpC1	4039337	p.Thr456Gln	missense_variant	0.56	pyrazinamide
clpC1	4039349	c.1356C>T	synonymous_variant	0.56	pyrazinamide
clpC1	4039352	c.1353C>G	synonymous_variant	0.56	pyrazinamide
clpC1	4039364	c.1341C>G	synonymous_variant	0.61	pyrazinamide
clpC1	4039391	c.1314T>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039409	c.1296T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039415	p.Glu430Asp	missense_variant	1.0	pyrazinamide	Uncertain significance
clpC1	4039481	c.1224T>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039484	c.1221T>G	synonymous_variant	0.75	pyrazinamide
clpC1	4039508	c.1197G>C	synonymous_variant	0.79	pyrazinamide
clpC1	4039526	c.1179G>A	synonymous_variant	0.77	pyrazinamide
clpC1	4039532	c.1173C>T	synonymous_variant	0.77	pyrazinamide
clpC1	4039553	c.1152C>A	synonymous_variant	0.76	pyrazinamide
clpC1	4039562	c.1143C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039565	c.1140G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039576	p.Ala377Ser	missense_variant	1.0	pyrazinamide
clpC1	4039577	c.1128T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039583	c.1122C>T	synonymous_variant	0.76	pyrazinamide
clpC1	4039622	c.1083C>T	synonymous_variant	0.77	pyrazinamide
clpC1	4039664	c.1041G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039670	c.1035G>C	synonymous_variant	0.47	pyrazinamide
clpC1	4039694	c.1011G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039724	c.981A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039751	c.954A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039757	c.948A>G	synonymous_variant	0.76	pyrazinamide
clpC1	4039760	c.945T>C	synonymous_variant	0.76	pyrazinamide
clpC1	4039766	c.939T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039769	c.936C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039775	c.930G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039778	c.927A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039781	c.924G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039790	c.915C>G	synonymous_variant	0.78	pyrazinamide
clpC1	4039817	c.888A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039826	c.879C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039865	c.840T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039898	c.807C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039931	c.774T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039937	c.768G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039946	c.759A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039952	c.753T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039982	c.723G>A	synonymous_variant	0.5	pyrazinamide	Not assoc w R - Interim
clpC1	4039988	c.717C>G	synonymous_variant	0.48	pyrazinamide
clpC1	4039991	c.714G>C	synonymous_variant	0.46	pyrazinamide
clpC1	4040021	c.684A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040024	c.681A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040033	c.672G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040036	c.669C>G	synonymous_variant	0.48	pyrazinamide
clpC1	4040090	c.613_615delTCTinsAGC	synonymous_variant	1.0	pyrazinamide
clpC1	4040093	c.612C>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040105	c.600C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040147	c.558A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040162	c.543G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040165	c.540G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040171	c.534C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040195	c.510G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4040200	c.505T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040201	c.504C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040204	c.501G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040207	c.498T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040213	c.490_492delTCTinsAGC	synonymous_variant	1.0	pyrazinamide
clpC1	4040225	c.480A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040228	c.477G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040231	c.474C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4040246	c.459C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040249	c.456A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040267	c.438A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040273	c.432T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040291	c.414G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040342	c.363C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040354	c.351A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040369	c.336C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040380	c.325T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040387	c.318A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040393	c.312G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040411	c.294T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040419	c.286C>T	synonymous_variant	0.65	pyrazinamide
clpC1	4040423	c.282A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040426	c.279T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040431	c.274T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040444	c.261C>T	synonymous_variant	0.46	pyrazinamide
clpC1	4040450	c.255A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040456	c.249C>T	synonymous_variant	0.57	pyrazinamide	Not assoc w R - Interim
clpC1	4040459	c.246C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040462	c.243C>T	synonymous_variant	0.52	pyrazinamide
clpC1	4040465	c.240T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040471	c.234T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040477	c.228G>C	synonymous_variant	0.48	pyrazinamide
clpC1	4040480	c.225T>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040486	c.219G>C	synonymous_variant	0.5	pyrazinamide
clpC1	4040495	c.210C>A	synonymous_variant	0.52	pyrazinamide
clpC1	4040522	c.183T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040525	c.180C>T	synonymous_variant	0.52	pyrazinamide	Not assoc w R - Interim
clpC1	4040528	c.177G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040531	c.174T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040534	c.171A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040537	c.168G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040546	c.159G>C	synonymous_variant	0.46	pyrazinamide
clpC1	4040551	c.154T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040561	c.144A>G	synonymous_variant	1.0	pyrazinamide
panD	4045067	c.-786C>G	upstream_gene_variant	0.7	pyrazinamide
panD	4045070	c.-789C>T	upstream_gene_variant	0.7	pyrazinamide
panD	4045076	c.-795A>C	upstream_gene_variant	0.7	pyrazinamide
glpK	4138418	c.1338T>C	synonymous_variant	0.8	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138568	c.1188A>C	synonymous_variant	0.92	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138580	c.1176C>T	synonymous_variant	0.92	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138606	c.1150T>C	synonymous_variant	0.94	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138631	c.1125C>G	synonymous_variant	0.86	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138640	c.1116C>T	synonymous_variant	0.87	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138643	c.1113A>G	synonymous_variant	0.95	levofloxacin
					moxifloxacin
					isoniazid	Not assoc w R - Interim
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
glpK	4138646	c.1110G>C	synonymous_variant	0.96	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138670	c.1086G>C	synonymous_variant	0.97	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138681	p.Met359Val	missense_variant	0.97	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138682	c.1074C>G	synonymous_variant	0.77	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138702	p.Gln352Glu	missense_variant	0.77	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138703	c.1053C>T	synonymous_variant	0.77	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138706	c.1050C>G	synonymous_variant	0.77	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138714	p.Ala348Ser	missense_variant	0.81	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138715	c.1041G>A	synonymous_variant	0.81	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138718	c.1038T>C	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138724	c.1032A>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138751	c.1005T>C	synonymous_variant	0.71	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138757	c.999A>G	synonymous_variant	1.0	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
glpK	4138793	c.963T>G	synonymous_variant	0.57	levofloxacin
					moxifloxacin
					isoniazid
					streptomycin
					rifampicin
					ethambutol
embC	4240685	p.Thr275Ala	missense_variant	1.0	ethambutol
embC	4240690	c.828G>C	synonymous_variant	0.73	ethambutol
embC	4240698	p.Ala279Gly	missense_variant	0.67	ethambutol
embC	4240726	c.864G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embC	4240729	c.867C>G	synonymous_variant	0.64	ethambutol
embC	4240747	c.885C>T	synonymous_variant	0.56	ethambutol	Not assoc w R - Interim
embC	4240759	c.897C>G	synonymous_variant	0.56	ethambutol
embC	4240765	c.903C>G	synonymous_variant	0.56	ethambutol
embC	4240783	c.921G>C	synonymous_variant	0.94	ethambutol
embC	4240789	c.927T>C	synonymous_variant	0.94	ethambutol
embC	4240819	c.957A>G	synonymous_variant	0.9	ethambutol
embC	4240828	c.966G>A	synonymous_variant	0.77	ethambutol
embC	4240831	c.969T>G	synonymous_variant	0.92	ethambutol
embB	4245737	c.-777A>C	upstream_gene_variant	1.0	ethambutol
embB	4245740	c.-774T>C	upstream_gene_variant	1.0	ethambutol
embB	4245764	c.-750G>C	upstream_gene_variant	1.0	ethambutol
embA	4245772	p.Asn847Thr	missense_variant	1.0	ethambutol
embA	4245785	c.2553G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4245807	c.-707_-705delTTAinsCTG	upstream_gene_variant	1.0	ethambutol
embB	4245812	c.-702G>C	upstream_gene_variant	1.0	ethambutol
embA	4245813	p.Pro861Ala	missense_variant	1.0	ethambutol
embA	4245820	p.Ser863Thr	missense_variant	1.0	ethambutol
embB	4245824	c.-690G>C	upstream_gene_variant	1.0	ethambutol
embB	4245833	c.-681G>C	upstream_gene_variant	0.93	ethambutol
embB	4245842	c.-672G>C	upstream_gene_variant	1.0	ethambutol
embB	4245845	c.-669T>C	upstream_gene_variant	1.0	ethambutol
embB	4245851	c.-663G>C	upstream_gene_variant	1.0	ethambutol
embB	4245860	c.-654C>G	upstream_gene_variant	1.0	ethambutol
embB	4246064	c.-450T>C	upstream_gene_variant	1.0	ethambutol
embA	4246080	p.Pro950Ser	missense_variant	1.0	ethambutol
embA	4246088	c.2856A>G	synonymous_variant	1.0	ethambutol	Not assoc w R
embB	4246097	c.-417C>G	upstream_gene_variant	1.0	ethambutol
embA	4246103	c.2871C>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4246109	c.-405C>G	upstream_gene_variant	1.0	ethambutol
embB	4246115	c.-399T>G	upstream_gene_variant	1.0	ethambutol
embA	4246128	p.Ser966Thr	missense_variant	1.0	ethambutol
embA	4246138	p.Arg969Gln	missense_variant	1.0	ethambutol
embB	4246140	c.-374T>C	upstream_gene_variant	1.0	ethambutol
embA	4246143	p.Ile971Val	missense_variant	1.0	ethambutol
embA	4246151	c.2919A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embA	4246152	p.Ala974Gln	missense_variant	1.0	ethambutol
embB	4246157	c.-357A>G	upstream_gene_variant	1.0	ethambutol
embA	4246164	c.2932T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4246184	c.-330A>C	upstream_gene_variant	1.0	ethambutol
embB	4246196	c.-318C>G	upstream_gene_variant	1.0	ethambutol
embB	4246205	c.-309A>G	upstream_gene_variant	1.0	ethambutol
embB	4246211	c.-303T>C	upstream_gene_variant	1.0	ethambutol
embA	4246329	p.Thr1033Ala	missense_variant	1.0	ethambutol
embB	4247407	c.894G>C	synonymous_variant	1.0	ethambutol
embB	4247425	c.912G>C	synonymous_variant	1.0	ethambutol
embB	4247434	c.921C>G	synonymous_variant	0.5	ethambutol
embB	4247437	c.924A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247440	c.927C>G	synonymous_variant	0.5	ethambutol
embB	4247446	c.933C>T	synonymous_variant	0.5	ethambutol
embB	4247452	c.939C>G	synonymous_variant	0.52	ethambutol
embB	4247464	c.951C>G	synonymous_variant	0.43	ethambutol
embB	4247470	c.957T>C	synonymous_variant	1.0	ethambutol
embB	4247497	c.984T>C	synonymous_variant	1.0	ethambutol
embB	4247500	c.987C>G	synonymous_variant	0.61	ethambutol
embB	4247506	c.993C>G	synonymous_variant	0.64	ethambutol
embB	4247512	c.999T>C	synonymous_variant	1.0	ethambutol
embB	4247527	c.1014G>C	synonymous_variant	0.61	ethambutol
embB	4247539	c.1026T>C	synonymous_variant	1.0	ethambutol
embB	4247550	p.Ala346Asp	missense_variant	0.66	ethambutol
embB	4247554	c.1041T>C	synonymous_variant	1.0	ethambutol
embB	4247566	c.1053C>G	synonymous_variant	1.0	ethambutol
embB	4247572	c.1059A>C	synonymous_variant	1.0	ethambutol
embB	4247590	c.1077A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247611	c.1098G>T	synonymous_variant	0.29	ethambutol	Not assoc w R - Interim
embB	4247629	c.1116C>G	synonymous_variant	1.0	ethambutol
embB	4247632	c.1119C>G	synonymous_variant	1.0	ethambutol
embB	4247638	c.1125G>C	synonymous_variant	1.0	ethambutol
embB	4247656	c.1143A>G	synonymous_variant	1.0	ethambutol
embB	4247662	c.1149C>G	synonymous_variant	1.0	ethambutol
embB	4247683	c.1170C>G	synonymous_variant	0.39	ethambutol
embB	4247692	c.1179C>G	synonymous_variant	0.35	ethambutol
embB	4247746	c.1233C>T	synonymous_variant	0.8	ethambutol
embB	4247797	c.1284C>G	synonymous_variant	1.0	ethambutol
embB	4247800	c.1287A>T	synonymous_variant	1.0	ethambutol
embB	4247803	c.1290G>C	synonymous_variant	1.0	ethambutol
embB	4247815	c.1302C>G	synonymous_variant	1.0	ethambutol
embB	4247819	p.Val436Ile	missense_variant	1.0	ethambutol	Uncertain significance
embB	4247830	c.1317A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247836	c.1323A>G	synonymous_variant	0.93	ethambutol	Not assoc w R - Interim
embB	4247839	c.1326G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247866	c.1353G>C	synonymous_variant	1.0	ethambutol
embB	4247875	c.1362G>C	synonymous_variant	1.0	ethambutol
embB	4247876	c.1363C>T	synonymous_variant	1.0	ethambutol
embB	4247881	c.1368G>C	synonymous_variant	1.0	ethambutol
embB	4247887	c.1374C>T	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247893	c.1380C>T	synonymous_variant	1.0	ethambutol
embB	4247899	p.Met462Ile	missense_variant	1.0	ethambutol
embB	4247905	c.1392G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247909	c.1396T>C	synonymous_variant	1.0	ethambutol
embB	4247914	c.1401G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247932	c.1419C>G	synonymous_variant	1.0	ethambutol
embB	4247940	p.Leu476Trp	missense_variant	1.0	ethambutol
embB	4247945	c.1432T>C	synonymous_variant	1.0	ethambutol
embB	4247951	p.Ser480Ala	missense_variant	1.0	ethambutol
embB	4247956	c.1443G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247974	c.1461C>G	synonymous_variant	1.0	ethambutol
embB	4248007	c.1494C>G	synonymous_variant	1.0	ethambutol
embB	4248011	p.Ser500Arg	missense_variant	1.0	ethambutol
embB	4248014	p.Thr501Ala	missense_variant	0.95	ethambutol	Uncertain significance
embB	4248035	p.Val508Ile	missense_variant	1.0	ethambutol
embB	4248040	c.1527C>G	synonymous_variant	0.96	ethambutol
embB	4248041	p.Ala510Thr	missense_variant	1.0	ethambutol	Uncertain significance
embB	4248044	p.Lys511Ala	missense_variant	1.0	ethambutol
embB	4248070	c.1557T>C	synonymous_variant	1.0	ethambutol
embB	4248085	c.1572T>C	synonymous_variant	1.0	ethambutol
embB	4248097	c.1584C>G	synonymous_variant	1.0	ethambutol
embB	4248130	c.1617G>C	synonymous_variant	1.0	ethambutol
embB	4248142	c.1629T>C	synonymous_variant	1.0	ethambutol
embB	4248143	c.1630T>C	synonymous_variant	1.0	ethambutol
embB	4248157	c.1644A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4248172	c.1659G>C	synonymous_variant	0.62	ethambutol
embB	4248199	c.1686A>G	synonymous_variant	0.67	ethambutol
embB	4248200	p.Ile563Val	missense_variant	1.0	ethambutol
embB	4248205	c.1692C>G	synonymous_variant	0.74	ethambutol
embB	4248206	p.Ser565Gly	missense_variant	1.0	ethambutol	Uncertain significance
embB	4248220	c.1707A>C	synonymous_variant	1.0	ethambutol
embB	4248304	c.1791G>C	synonymous_variant	1.0	ethambutol
embB	4248316	c.1803C>G	synonymous_variant	1.0	ethambutol
embB	4248319	c.1806A>G	synonymous_variant	1.0	ethambutol
embB	4248343	c.1830G>C	synonymous_variant	0.86	ethambutol
embB	4248350	c.1837T>C	synonymous_variant	1.0	ethambutol
embB	4248355	c.1842A>G	synonymous_variant	0.85	ethambutol
embB	4248358	c.1845C>G	synonymous_variant	1.0	ethambutol
embB	4248361	c.1848A>C	synonymous_variant	1.0	ethambutol
embB	4248362	p.Ser617Ala	missense_variant	1.0	ethambutol
embB	4248373	c.1860C>G	synonymous_variant	1.0	ethambutol
embB	4248386	c.1873C>A	synonymous_variant	0.88	ethambutol
embB	4248407	p.Leu632Val	missense_variant	1.0	ethambutol
embB	4248410	p.Phe633Leu	missense_variant	1.0	ethambutol
embB	4248419	p.Leu636Met	missense_variant	1.0	ethambutol
embB	4248425	c.1912T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4248430	c.1917T>C	synonymous_variant	0.87	ethambutol
embB	4248432	p.Trp640Phe	missense_variant	1.0	ethambutol
embB	4248457	c.1944T>C	synonymous_variant	0.87	ethambutol
embB	4248472	c.1959T>C	synonymous_variant	1.0	ethambutol
embB	4248475	c.1962G>C	synonymous_variant	1.0	ethambutol
embB	4248504	p.Asp664Gly	missense_variant	1.0	ethambutol	Uncertain significance
embB	4248508	c.1995G>A	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4248512	p.Thr667Ser	missense_variant	1.0	ethambutol
embB	4249444	c.2931T>C	synonymous_variant	1.0	ethambutol
embB	4249469	p.Leu986Met	missense_variant	1.0	ethambutol
embB	4249486	c.2973T>G	synonymous_variant	1.0	ethambutol
embB	4249498	c.2985G>C	synonymous_variant	1.0	ethambutol

TB-Profiler result