Run ID: SRR3675390
Sample name:
Date: 2024-04-14T15:24:48.420648
Number of reads: 372439
Percentage reads mapped: 29.57
Median coverage: 10.0
Strain: La3;M.canetti;lineage4.2;lineage4.6.4;lineage4.9
Spoligotype:
Drug-resistance: MDR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.2 | Euro-American | None | 0.05 |
| lineage4.6.4 | Euro-American | None | 0.07 |
| lineage4 | Euro-American | None | 0.78 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.85 |
| La3 | M.orygis | None | 0.06 |
| M.canetti | M.canetti | None | 0.07 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| isoniazid | katG | c.496_498delGTTinsAC | Assoc w R | High-level resistance |
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| p.Tyr384Asn | Mutation from literature | |||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fbiC | c.562_564delTTGinsCT | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.751_753delTTGinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| fbiC | 1303492 | c.562_564delTTGinsCT | frameshift_variant&synonymous_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303681 | c.751_753delTTGinsCC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| katG | 2155614 | c.496_498delGTTinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| embB | 4247448 | p.His312Arg | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 1220 | p.Asn407Thr | missense_variant | 1.0 | isoniazid | |
| dnaA | 1222 | p.Thr408Ala | missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 1245 | c.1245G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1254 | c.1254T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1281 | c.1281C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1293 | c.1293T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1299 | c.1299G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1302 | c.1302C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1311 | c.1311C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1332 | c.1332A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1338 | c.1338T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1350 | c.1350G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1356 | c.1356T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1371 | c.1371T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1374 | c.1374G>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1375 | c.1375T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1383 | c.1383A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1389 | c.1389C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1392 | c.1392A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1404 | c.1404T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1416 | c.1416C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1441 | c.1441C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1449 | c.1449G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1458 | c.1458G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1464 | c.1464T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1467 | c.1467G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1473 | c.1473T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| gyrB | 5284 | c.45G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5287 | c.48T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5293 | c.54C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5302 | c.63A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5305 | c.66G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5308 | c.69G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5341 | c.102T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5359 | c.120C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 5363 | c.124_126delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 5377 | c.138T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 5422 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5425 | c.186A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5426 | p.Thr63Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5431 | c.192A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5434 | c.195G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5436 | p.Asn66Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrB | 5440 | c.201A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5449 | c.210T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5455 | c.216T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5470 | c.231C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5485 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5488 | c.249C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5491 | c.252T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5500 | c.261C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5502 | p.Thr88Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5812 | c.573C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5815 | c.576C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5819 | c.580C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 5824 | c.585A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5836 | c.597C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5851 | c.612G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6145 | c.906C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6178 | c.939C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6181 | c.942C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6196 | c.957C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6247 | c.1008G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6259 | p.Asp340Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6298 | c.1059C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6299 | c.1060C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 6331 | c.-971A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7151 | c.1912C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7165 | c.-137C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7838 | c.537C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7850 | c.549C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7886 | c.585T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7889 | c.588G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7892 | c.591G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8057 | c.756A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8069 | c.768T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8078 | c.777A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8084 | c.783G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8090 | c.789C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8096 | c.795T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8099 | c.798T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8105 | c.804G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8111 | c.810G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8121 | c.820T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8174 | c.873C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8189 | c.888G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8195 | c.894C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8199 | p.Ser300Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8217 | p.Ser306Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8225 | p.Asp308Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8235 | c.934_936delTTAinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | c.1039_1041delGCGinsTC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8393 | c.1092T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8402 | p.Asp367Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8421 | c.1120_1122delGTGinsAC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8433 | p.Thr378Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8447 | c.1146C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8450 | c.1149G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8510 | c.1209G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8513 | c.1212C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8561 | c.1260A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8562 | c.1261C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8571 | c.1270C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8609 | c.1308G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8627 | c.1326C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8633 | c.1332C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8645 | c.1344C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8666 | c.1365G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8694 | c.1393C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8723 | c.1422G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8732 | c.1431G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8752 | p.Ala484Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8783 | c.1482G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8795 | c.1494C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8796 | p.Ile499Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | c.1512C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8825 | c.1524G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8876 | c.1575C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8924 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8933 | c.1632G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8945 | c.1644G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9003 | c.1702C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9017 | c.1716C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9065 | c.1764C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9101 | c.1800A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9257 | c.1956C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9315 | c.2014C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9323 | c.2022C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9371 | c.2070G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9374 | c.2073G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9398 | c.2097T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9401 | c.2100G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9413 | c.2112G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9419 | c.2118T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9420 | p.Ile707Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9449 | c.2148C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9452 | c.2151G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9476 | c.2175G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9479 | c.2178G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9485 | c.2184A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9488 | c.2187G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9491 | c.2190C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9494 | c.2193T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9497 | c.2196G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9503 | c.2202T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9518 | c.2217A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9527 | c.2226A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9542 | c.2241T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9545 | c.2244A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9551 | c.2250G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9557 | c.2256G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9560 | c.2259C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9566 | c.2265C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9585 | c.2284T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9590 | c.2289T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9593 | c.2292G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9602 | c.2301T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9604 | p.Val768Ala | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9629 | c.2328C>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9644 | c.2343T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9650 | c.2349G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9656 | c.2355C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9659 | c.2358C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9668 | c.2367C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9689 | c.2388G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 490851 | c.69A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490853 | p.Ala24Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490863 | c.81C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490869 | c.87C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490890 | c.108C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490911 | c.129T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490921 | p.Gln47Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490935 | c.153C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490945 | c.163C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490962 | c.180T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490971 | c.189A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490974 | c.192T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490980 | p.Asn66Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490984 | p.Leu68Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490995 | c.213C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490998 | c.216T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491067 | c.285C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491077 | p.Asn99Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491085 | c.303T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491091 | c.309T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491094 | c.312C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491142 | c.360C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491151 | c.369G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491154 | p.Glu124Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491163 | c.381G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491166 | c.384G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491226 | c.444C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491265 | c.483G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491523 | c.741G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491553 | c.771G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491604 | c.822G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491628 | c.846G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575561 | p.Met72Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575586 | p.Ala80Gly | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575590 | c.243T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575593 | c.246G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575596 | c.249C>T | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575629 | c.282A>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575633 | c.286_288delGCAinsAG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575652 | p.Arg102Gln | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575662 | c.315C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575665 | c.318G>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575686 | c.339G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575692 | c.345G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575732 | c.385_387delCTTinsTG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575767 | c.420G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575770 | c.423G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575772 | p.Val142Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575848 | c.501C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575872 | c.525C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575902 | c.555C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619669 | c.-222G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619672 | c.-219A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619681 | c.-210G>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619697 | c.-194A>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619708 | c.-183G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619713 | c.-178_-177delCGinsTC | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619720 | c.-171C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619727 | c.-164_-162delACGinsGC | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619734 | c.-157_-156delCGinsATACCCCC | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619744 | c.-147A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619766 | c.-125A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619771 | c.-120C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | p.Leu119Met | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620257 | p.Ile123Val | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620271 | c.381C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620290 | p.Tyr134Asn | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620314 | c.424C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620325 | c.435G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620337 | c.447C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620358 | c.468C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620397 | c.507C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620404 | c.514C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620418 | c.528G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620571 | c.681A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| Rv0565c | 657219 | p.Ala84Glu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657233 | p.Ile80Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657240 | c.229_231delGAAinsAG | frameshift_variant&synonymous_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657243 | c.228C>A | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657267 | c.202_204delTCGinsAGC | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657300 | c.171C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657303 | c.168C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657686 | c.-216C>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731738 | c.-192G>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731753 | c.-177A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731795 | c.-135C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732238 | c.309G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732247 | c.318C>T | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732250 | c.321C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732263 | p.Val112Met | missense_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732319 | c.390G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732322 | p.Glu131Asp | missense_variant | 1.0 | isoniazid | |
| hadA | 732329 | c.400_402delCTCinsAT | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732361 | c.432C>T | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732376 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.449_450insGGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732381 | p.Glu151Val | missense_variant | 0.9 | isoniazid | |
| hadA | 732391 | c.462T>A | synonymous_variant | 1.0 | isoniazid | |
| nusG | 734352 | c.99T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734361 | c.108C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734370 | c.117A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734376 | c.123G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734481 | c.228C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734616 | c.363C>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734631 | c.378G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734634 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734643 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734652 | c.399T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734661 | c.408A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734664 | c.411T>G | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734670 | c.417G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734673 | c.420A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734680 | p.Ala143Ser | missense_variant | 1.0 | rifampicin | |
| nusG | 734703 | c.450T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734781 | c.528A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734790 | c.537G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734793 | c.540C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760106 | c.300G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760172 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760193 | c.387C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760202 | c.396G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760256 | c.450C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760343 | c.537G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760409 | c.603C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760412 | c.606C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760415 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760418 | c.612G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760445 | c.639C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760604 | c.798G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760607 | c.801G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760625 | c.819C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760920 | c.1114C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760971 | c.1165C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760994 | c.1188G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761006 | c.1200C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761066 | c.1260G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761183 | c.1377T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761201 | c.1395G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761204 | c.1398C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761502 | p.Pro566Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761603 | c.1797C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761682 | c.1876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761687 | c.1881C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761693 | c.1887G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761708 | c.1902C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761822 | c.2016C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761870 | p.Asp688Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761876 | c.2070C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761913 | c.2107_2109delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761990 | c.2184G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762011 | c.2205G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762020 | c.2214G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762024 | c.2218_2220delGTGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762071 | c.2265C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762119 | c.2313C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762134 | c.2328C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762224 | c.2418C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762236 | c.2430G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762269 | c.2463G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762278 | c.2472C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762486 | p.Pro894Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 762518 | c.-852C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762557 | c.-813G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762581 | c.-789T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762587 | c.-783G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762599 | c.-771T>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762776 | c.-594C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | c.3007_3009delATGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762830 | c.-540C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762860 | c.-510G>T | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 762899 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763050 | c.-320C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763076 | c.-294C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763124 | c.-246C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763435 | c.66A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763505 | c.136C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763561 | c.192G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763600 | c.231C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763606 | c.237C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763618 | c.249C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763639 | c.270G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763666 | c.297G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763699 | c.330G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763771 | c.402C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763781 | p.Ser138Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763819 | c.450G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763867 | c.498C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763916 | p.Glu183Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763948 | c.579G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763951 | c.582G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763987 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 764119 | c.750G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764217 | p.Asn283Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 764254 | c.885G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764272 | c.903G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764284 | c.915G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764317 | c.948C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764344 | c.975C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764347 | c.978G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764419 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764524 | c.1155C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764533 | c.1164C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764536 | c.1167G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764587 | c.1218C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764648 | c.1279C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764653 | c.1284G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764656 | c.1287C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764674 | c.1305G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764681 | c.1312C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764755 | c.1386C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764767 | c.1398G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764800 | c.1431G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764830 | c.1461C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764833 | c.1464A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764902 | c.1533C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764918 | c.1549_1551delGTGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765496 | c.2127C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765526 | c.2157C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765541 | c.2172C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765547 | c.2178C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765583 | c.2214G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765586 | c.2217G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765589 | c.2220G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765610 | c.2241C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765612 | p.His748Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765622 | p.Glu751Asp | missense_variant | 0.95 | rifampicin | |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765676 | c.2307G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765688 | c.2319G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765689 | c.2320C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765694 | c.2325G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765724 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765727 | c.2358T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765748 | c.2379C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 765757 | c.2388C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765790 | c.2421C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765910 | c.2541G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765952 | c.2583G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765997 | c.2628T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766043 | p.Gln892Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766070 | c.2701C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 766270 | c.2901G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766280 | p.Ser971Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766300 | c.2931C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766303 | c.2934C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766306 | c.2937C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766315 | c.2946C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766324 | c.2955C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766351 | c.2982C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766360 | c.2991C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766387 | c.3018C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766397 | c.3028C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766417 | c.3048C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766495 | c.3126C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766519 | c.3150C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766537 | c.3168G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766543 | c.3174C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.92 | rifampicin | |
| rpoC | 766621 | c.3252G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766654 | c.3285C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766681 | c.3312C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766684 | c.3315C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766700 | c.3331C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766714 | c.3345G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766747 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766792 | c.3423C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766795 | c.3426C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766801 | c.3432C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766907 | c.3538C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766975 | c.3606C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767185 | c.3816G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767200 | c.3831G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767206 | c.3837C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767209 | c.3840T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781721 | c.162C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781847 | c.288G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781880 | c.321C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800237 | c.-572T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800244 | c.-565A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800267 | c.-542T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800272 | c.-537C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800278 | c.-531A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800285 | c.-524_-523insC | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800295 | c.-513_-502delCTTGAAATTGAT | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800311 | c.-498delGinsCT | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800321 | c.-488T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800341 | c.-468G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800349 | c.-460delCinsGT | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800358 | c.-450delT | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.93 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800579 | c.-230C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800597 | c.-212A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800609 | c.-200G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800714 | c.-95C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800735 | c.-74C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800783 | c.-26C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800797 | c.-12T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800799 | c.-10G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800800 | c.-9G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800801 | c.-8A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800817 | c.9A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800913 | c.105G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800922 | c.114C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800955 | c.147C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800958 | c.150G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 800976 | c.168G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801210 | c.402T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801216 | c.408C>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801219 | c.411C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801220 | p.Ser138Ala | missense_variant | 1.0 | linezolid | |
| rplC | 801246 | c.438C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801252 | c.444G>C | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303464 | c.534A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303467 | c.537C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303476 | c.546G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303479 | c.549G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303488 | c.558G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303503 | c.573G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303551 | c.621G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303578 | c.648G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303584 | c.654C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303611 | c.681G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303614 | c.684C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303620 | c.690C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303644 | c.714G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303661 | p.Val244Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303689 | c.759T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303731 | c.801A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303768 | p.Ser280Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304091 | c.1161C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304112 | c.1182G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304625 | c.1695C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304628 | c.1698G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304649 | c.1719C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304661 | c.1731C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304679 | c.1749G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304703 | c.1773C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304715 | c.1785G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304751 | c.1821C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304790 | c.1860C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304799 | c.1869G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304809 | p.Ser627Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304832 | c.1902C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305066 | c.2136T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305069 | c.2139G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305074 | p.Ser715Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305078 | c.2148A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305088 | p.Val720Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305111 | c.2181C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1305117 | c.2187T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305120 | c.2190G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305126 | c.2196T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1305150 | c.2220C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305154 | c.2224T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305159 | c.2229G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305162 | c.2232C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305165 | c.2235G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305186 | c.2256C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305192 | c.2262C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305195 | c.2265T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364844 | c.432C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364847 | c.435G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364866 | c.454_456delGCTinsAC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364889 | c.477A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364898 | c.486C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364922 | p.Glu170Asp | missense_variant | 1.0 | pyrazinamide | |
| atpE | 1461101 | c.57T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461107 | c.63C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461131 | c.87T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461161 | c.117C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461167 | c.123G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>A | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461224 | c.180T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461230 | c.186G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461233 | c.189A>C | synonymous_variant | 1.0 | bedaquiline | |
| rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| inhA | 1673547 | c.-655T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673568 | c.-634C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673574 | c.-628C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673589 | c.-613A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673596 | p.Lys53Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673609 | p.Gly57Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673616 | c.-586A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673619 | c.-583T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673679 | c.-523T>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673682 | c.-520G>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1673685 | c.-517C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673710 | c.271_273delCTAinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673715 | c.-487C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673730 | c.-472C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673733 | p.Met98Ile | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673736 | c.-466G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673767 | p.Asn110Asp | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673955 | c.-247G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673960 | p.Ala174Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673970 | c.-232C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673976 | c.-226T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673982 | c.-220G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673988 | c.-214G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673991 | c.-211C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674015 | c.-187C>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674018 | c.-184G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674033 | c.-169T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674037 | p.Gln200Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674675 | c.474C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674858 | c.657G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674882 | c.681G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674885 | c.684C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674912 | c.711G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674957 | c.756G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833256 | c.-286C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833262 | c.-280T>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833271 | c.-271G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833593 | c.52_54delTCTinsAC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833604 | c.63C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833610 | c.69C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833694 | c.153G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833718 | c.177C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833754 | c.213G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833850 | c.309C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834024 | c.483G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834051 | c.510G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834135 | c.594G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834148 | c.607C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCA | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834174 | c.633C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834336 | c.795C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834339 | c.798C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834369 | c.828C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834495 | c.954G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834615 | c.1074C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834618 | c.1077G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853360 | c.-246G>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853393 | c.-213C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853408 | c.-198C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853426 | c.-180G>A | upstream_gene_variant | 1.0 | linezolid | |
| bacA | 2063640 | p.Asp363Glu | missense_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063643 | c.1086C>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063646 | c.1083G>A | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063658 | c.1071A>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063667 | c.1062G>A | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | Not assoc w R - Interim | |||||
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| bacA | 2063676 | c.1053C>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063697 | c.1032A>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063703 | c.1026C>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064096 | p.Ala211Gly | missense_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064099 | c.630G>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064111 | c.618C>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064114 | c.615T>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064117 | c.612T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064120 | c.609G>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064123 | c.606T>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064129 | c.600C>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064132 | p.Ala199Val | missense_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064135 | c.594G>A | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064150 | c.579T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064155 | p.Val192Ile | missense_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064165 | c.564T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| katG | 2155596 | c.516G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155600 | p.Cys171Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155617 | c.495T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155632 | c.480A>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155637 | p.Leu159Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155641 | p.Lys157Asn | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155649 | p.Tyr155His | missense_variant | 1.0 | isoniazid | |
| katG | 2155680 | c.432G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517956 | c.-159G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518025 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518252 | c.138C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518279 | c.165T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518312 | c.198T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518348 | c.234A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518439 | p.Ala109Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518444 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518447 | c.333T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518459 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518462 | c.348A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518468 | c.354A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518471 | c.357C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518475 | c.361A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518492 | c.378C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518513 | c.399C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518537 | c.423C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518573 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518618 | c.504G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518633 | c.519G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518648 | c.534C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518681 | c.567C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518735 | c.621C>A | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518744 | c.630C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518756 | c.642G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518798 | c.684G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518816 | c.702C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518822 | c.708C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518855 | c.741C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518856 | p.Ile248Leu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518894 | c.780G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518903 | c.789C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518910 | c.796C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518939 | c.825T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518942 | c.828T>C | synonymous_variant | 1.0 | isoniazid | |
| Rv2477c | 2782861 | c.1182T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782864 | c.1179T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782897 | c.1146G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782905 | p.Val380Ile | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782918 | c.1125C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782928 | p.Thr372Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782930 | c.1113G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782999 | c.1044C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783737 | c.306C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783749 | c.292_294delATCinsGA | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | c.222A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783837 | p.Thr69Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783842 | c.201C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783848 | c.195C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783926 | c.117C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783935 | c.108C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783950 | c.93C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783953 | c.90G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | c.87T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2784348 | c.-306G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784351 | c.-309C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784354 | c.-312T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784358 | c.-316T>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784366 | c.-324G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784375 | c.-333T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784378 | c.-336A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784381 | c.-339T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784396 | c.-354A>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784414 | c.-372A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784417 | c.-375C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784428 | c.-386T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784429 | c.-387A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784432 | c.-390A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784438 | c.-396G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784441 | c.-399G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784445 | c.-403C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784456 | c.-414A>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784465 | c.-423T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2681 | 2997183 | c.445C>T | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997189 | p.Ala151Thr | missense_variant | 1.0 | capreomycin | |
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065163 | c.1029C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065442 | c.750T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065451 | c.741G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065457 | c.735A>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065463 | c.729T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065469 | c.723C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065478 | c.714C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065481 | c.711T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065484 | c.708G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065487 | c.705T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065490 | c.702A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065493 | c.699G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065499 | c.693A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065502 | p.Asp230Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065508 | c.684T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065517 | c.673_675delCTCinsTG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065532 | c.660A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065556 | c.636G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065580 | c.612G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065583 | c.609G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065594 | c.598C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065595 | p.Leu199Phe | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065612 | p.Thr194Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065625 | c.567G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065634 | c.558G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065637 | c.555A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065640 | c.552T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065652 | c.540C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065658 | p.Pro178Leu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065661 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065666 | c.526T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065675 | p.Phe173Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065699 | p.Ile165Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065703 | c.489A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067325 | c.621A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067331 | c.615C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067784 | c.162C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067787 | p.Lys53Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067832 | c.114C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067838 | c.108C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073997 | c.475C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074045 | c.427C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074056 | p.Glu139Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074061 | p.Glu137Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074307 | c.165A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074313 | c.159A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074334 | c.138T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074349 | c.123T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074355 | c.117G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074360 | c.112T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074361 | c.111T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074367 | c.103_105delCGCinsAG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074370 | p.Met34Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3623411 | c.1500T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623428 | c.1483T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623443 | p.Ser490Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623444 | c.1467T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623468 | c.1443T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623471 | c.1440C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623489 | c.1422C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623492 | c.1419T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623510 | c.1401C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623531 | p.Gly460Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623549 | c.1362C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623561 | c.1350T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623564 | c.1347C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623756 | c.1155G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623782 | p.Val377Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623987 | c.924G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624002 | c.909G>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624008 | c.903T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624014 | c.897T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624017 | p.Thr298Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624023 | c.888G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624026 | c.885G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624041 | p.Glu290Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624071 | c.840C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624080 | c.831G>A | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624263 | c.648T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624276 | p.Arg212His | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624280 | p.Ala211Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624290 | c.621C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624301 | p.Ala204Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624302 | c.609G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624308 | c.603A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624314 | c.597C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624317 | c.594C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624323 | c.588G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624339 | p.Arg191His | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624341 | c.570C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624356 | c.555C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624368 | c.543C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624389 | c.522C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624406 | c.505C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625327 | c.-417A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625366 | c.-456C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625381 | c.-471T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625384 | c.-474G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625387 | c.-477T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625396 | c.-486G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625405 | c.1207_1209delCAGinsGA | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625408 | c.1204_1206delGAGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625414 | c.-504C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625419 | c.1195C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625420 | p.Asp398Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625426 | c.-516G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625432 | c.-522G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625459 | c.-549C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625465 | c.-555T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625471 | c.-561C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625474 | c.-564G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625480 | p.Asn378Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625486 | c.-576G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625489 | c.-579A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625497 | c.1117T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625510 | c.-600T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625522 | c.-612C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625572 | p.Thr348Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625588 | c.-678G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625612 | c.-702G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625615 | c.-705G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625633 | c.981C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625684 | c.-774G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625747 | c.-837G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625750 | c.864G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625798 | c.-888G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625803 | c.-893C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625804 | c.808_810delAGGinsCA | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625819 | c.795G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625837 | c.-927C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625915 | c.699G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625972 | c.642G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625978 | c.636T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625989 | p.Thr209Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625993 | c.621G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625999 | c.615A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626006 | p.Ser203Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626008 | c.606G>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626029 | c.585A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626043 | p.Ala191Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626054 | p.Leu187Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626062 | c.552T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626065 | c.549G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626070 | p.Ile182Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626071 | c.543C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626074 | c.540G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626083 | c.531G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626088 | p.Ser176Ala | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3626092 | c.522T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626095 | p.Glu173Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626101 | p.Gln171His | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626107 | c.507G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626119 | c.495C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626372 | p.Ile81Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626383 | c.231G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626386 | c.228G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626390 | p.Arg75Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626394 | p.Val74Leu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626395 | c.219G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626400 | p.Ile72Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626410 | c.204T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626413 | c.201T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626711 | c.-98T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626776 | c.-163A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626843 | c.-230G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626849 | c.-236C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626930 | c.-317A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626936 | c.-323C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626945 | c.-332C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626963 | c.387G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626981 | c.-368C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626990 | c.-377G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627002 | c.-389G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627032 | c.-419G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627056 | c.294C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627140 | c.-527G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627155 | c.-542C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627188 | c.160_162delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627287 | c.-674C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627311 | c.39C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | ||||||
| mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627323 | c.25_27delTTGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiA | 3640247 | c.-296T>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640260 | c.-283T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640261 | c.-282C>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640269 | c.-274A>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640282 | c.-261C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640298 | c.-245A>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640318 | c.-225A>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640365 | c.-178C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641909 | c.375T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641924 | c.390A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641925 | p.Thr131Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641928 | c.394T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641948 | c.414G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641951 | c.417G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641957 | c.423C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rpoA | 3877533 | c.975C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877567 | p.Ser314Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877569 | c.939G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877575 | c.933C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877593 | c.915C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877602 | c.906C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877620 | c.888G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877647 | c.861C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877659 | c.849G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877674 | c.834C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877679 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877685 | c.823C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877689 | c.819C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877731 | c.777G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877734 | c.774G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877746 | c.762G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877752 | c.756C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877755 | c.753C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877836 | c.672A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877886 | c.622C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877899 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877909 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877929 | c.579C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877950 | c.558C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878043 | c.465G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878058 | c.450G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878085 | c.423G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878097 | c.411G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878100 | c.408C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878126 | c.382C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878172 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878202 | c.306G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878211 | c.297G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878262 | c.246C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878295 | c.213A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878364 | c.144A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878376 | c.132G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878381 | c.127C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878391 | c.117T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878403 | c.105C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878406 | c.102G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878412 | c.96C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878424 | c.84G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | p.Val22Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878713 | c.-206G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878719 | c.-212G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878728 | c.-221G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878791 | c.-284C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878836 | c.-330_-329delAGinsCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878920 | c.-413C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878962 | c.-455G>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878977 | c.-470C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879004 | c.-499_-497delAAGinsCGA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879043 | c.-536C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879100 | c.-593G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879148 | c.-641G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879235 | c.-728C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879238 | c.-731C>T | upstream_gene_variant | 1.0 | rifampicin | |
| clpC1 | 4038314 | c.2391T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038335 | c.2370C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038344 | c.2361G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038350 | c.2355C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038383 | c.2322G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038407 | c.2298G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038436 | p.Ala757Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038508 | c.2197C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038519 | p.Arg729Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038533 | c.2172C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038536 | c.2169C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038587 | c.2118C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038665 | c.2040C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038668 | c.2037G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038677 | c.2028G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038686 | c.2019C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038695 | c.2010C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038698 | c.2007C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038703 | c.2002C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038800 | c.1905C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038838 | c.1867C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038839 | c.1866G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038902 | c.1803C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038980 | c.1725C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038995 | c.1710G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039009 | c.1696C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039037 | c.1668T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039090 | c.1615C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | c.1368A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1261_1263delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039448 | c.1257A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039454 | c.1251A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039493 | c.1212C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039514 | c.1191C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039541 | c.1164C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039552 | c.1153C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039553 | c.1152C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039574 | p.Ala377Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039586 | c.1119G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039601 | c.1104G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039693 | c.1012C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039754 | c.951G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039763 | c.942C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039766 | c.939T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039784 | c.921C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039787 | c.916_918delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039802 | c.903G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039868 | c.837C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039942 | c.763C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039996 | p.Glu237Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040018 | c.687G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040036 | c.669C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040510 | c.195G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040513 | c.192G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040594 | c.111G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040600 | c.105A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043865 | c.415_417delGGAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| panD | 4043876 | p.Leu136Ile | missense_variant | 1.0 | pyrazinamide | |
| panD | 4043880 | c.402C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4043889 | c.393G>A | synonymous_variant | 1.0 | pyrazinamide | |
| glpK | 4138418 | c.1338T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138424 | c.1332T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138429 | c.1327T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138451 | c.1305T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138456 | c.1300C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138459 | p.Asp433Asn | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138465 | p.Gly431Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138472 | c.1284G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138490 | c.1264_1266delGTGinsAT | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138862 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138868 | c.888G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138877 | c.879A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138880 | c.876T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138889 | c.867G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138898 | c.858T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138910 | c.846G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138913 | c.843T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138919 | c.837C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138922 | c.834A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138925 | c.831G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138931 | c.825G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138934 | c.820_822delCCAinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138938 | p.Ala273Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138943 | c.813T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138946 | c.810C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138949 | c.807A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138973 | c.783T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139588 | c.168G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139594 | c.162C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139600 | c.156G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139633 | c.123C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139648 | c.108T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139651 | p.His35Arg | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240123 | c.261C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240128 | p.Gln89Arg | missense_variant | 1.0 | ethambutol | |
| embC | 4240150 | c.288A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240151 | p.Ser97Pro | missense_variant | 1.0 | ethambutol | |
| embC | 4240171 | c.309G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240175 | c.313T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240777 | c.915G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 0.92 | ethambutol | |
| embC | 4240795 | c.933C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240801 | c.939C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240858 | c.996G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240859 | p.Leu333Met | missense_variant | 1.0 | ethambutol | |
| embC | 4240867 | c.1005T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240876 | c.1014C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240879 | c.1017G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240886 | p.Ile342Val | missense_variant | 1.0 | ethambutol | |
| embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240900 | c.1038A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240918 | c.1056G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240924 | c.1062C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240945 | c.1083T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241026 | c.1164C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241056 | c.1194C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241153 | p.Ile431Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241713 | c.1851G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241719 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241728 | c.1866C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242838 | c.-395C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242863 | p.Tyr1001Asn | missense_variant | 1.0 | ethambutol | |
| embA | 4242871 | c.-362C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242873 | p.Asp1004Val | missense_variant | 1.0 | ethambutol | |
| embA | 4244780 | c.1548C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244783 | c.1551C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244786 | c.1554G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244792 | c.1560G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244802 | p.Leu524Met | missense_variant | 0.93 | ethambutol | |
| embA | 4244805 | c.1573C>T | synonymous_variant | 0.93 | ethambutol | |
| embA | 4244808 | c.1576_1578delTTCinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4244822 | c.1590G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244823 | p.Val531Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244856 | p.Ala542Pro | missense_variant | 1.0 | ethambutol | |
| embA | 4245101 | c.1869G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245110 | c.1878C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245186 | p.Thr652Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245194 | c.1962G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245195 | c.1963_1965delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245200 | c.1968C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245206 | c.1974A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245224 | c.1992T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245248 | c.2016G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245257 | c.2025A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245263 | c.2031A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245281 | c.2049C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245285 | c.2053T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245345 | p.Met705Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245355 | p.Ala708Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245368 | c.2136T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245674 | c.2442A>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245677 | c.-837G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245683 | c.-831C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245693 | p.Ile821Val | missense_variant | 1.0 | ethambutol | |
| embB | 4245714 | c.-800C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245725 | c.-789A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245726 | c.-788T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245734 | c.-780G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245737 | c.-777A>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245764 | c.-750G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245772 | p.Asn847Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245803 | c.-711C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245806 | c.-708G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245807 | c.2575_2577delTTAinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4245812 | c.-702G>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245813 | p.Pro861Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245822 | p.Pro864Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4245839 | c.-675G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245843 | c.2611_2613delGTTinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4245848 | c.-666C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245851 | c.-663G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245857 | c.-657C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245869 | c.2637C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245875 | c.-639G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245887 | c.-627T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245891 | p.Ile887Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245935 | c.2703G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245942 | p.Arg904Gly | missense_variant | 1.0 | ethambutol | |
| embB | 4245953 | c.-561A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245956 | c.-558G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246013 | c.-501T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246020 | p.Ala930Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4246028 | c.2796G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246070 | c.-444G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246115 | c.-399T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246128 | c.2896_2898delTCTinsAG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4246138 | p.Arg969Gln | missense_variant | 1.0 | ethambutol | |
| embB | 4246140 | c.-374T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246148 | c.-366G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246151 | c.-363A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246152 | p.Ala974Arg | missense_variant | 1.0 | ethambutol | |
| embB | 4246172 | c.-342C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246184 | c.-330A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246205 | c.-309A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246211 | c.-303T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246217 | c.-297G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246220 | c.2988T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246223 | c.-291C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246227 | c.2995_2997delATTinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4246235 | c.3003G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246244 | c.-270G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246254 | p.Leu1008Met | missense_variant | 1.0 | ethambutol | |
| embB | 4246259 | c.-255G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246265 | c.3033C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246268 | c.-246G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246279 | p.Ala1016Val | missense_variant | 1.0 | ethambutol | |
| embB | 4246292 | c.-222A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246307 | c.-207G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246316 | c.-198T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246346 | c.-168C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246359 | c.3127_3129delGCCinsTG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4246373 | c.-141T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246376 | c.-138G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246398 | p.Ser1056Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4247440 | c.927C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247555 | c.1042_1044delCTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247579 | p.Ala356Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247608 | c.1095G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247611 | c.1098G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247632 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247657 | p.Pro382Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4247671 | c.1158G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247679 | p.Met389Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4247684 | c.1171T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247722 | c.1209G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247725 | c.1212G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247728 | c.1215G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247743 | c.1230C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247839 | c.1326G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247858 | c.1345C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247899 | p.Met462Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247911 | p.Leu466Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4247915 | p.Arg468Lys | missense_variant | 1.0 | ethambutol | |
| embB | 4247920 | c.1407T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247923 | c.1410T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247932 | c.1419C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247948 | p.Val479Leu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4247975 | p.Val488Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4247989 | c.1476G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248001 | c.1488C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248007 | c.1494C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248042 | p.Ala510Gly | missense_variant | 1.0 | ethambutol | |
| embB | 4248052 | c.1539G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248055 | c.1542G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248058 | c.1545C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248061 | c.1548G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248064 | c.1551G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248094 | c.1581C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248154 | c.1641G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248163 | c.1650G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248169 | c.1656C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248175 | c.1662G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248178 | c.1665C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248214 | c.1701C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248217 | c.1704C>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4248220 | c.1707A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248233 | c.1720C>T | synonymous_variant | 0.96 | ethambutol | |
| embB | 4248252 | p.Gly580Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248266 | c.1753C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248277 | c.1764G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248280 | c.1767C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248334 | c.1821C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248349 | c.1836G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248358 | c.1845C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248361 | c.1848A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248379 | c.1866G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248407 | c.1894_1896delTTAinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248412 | p.Phe633Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4248416 | p.Leu635Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248424 | c.1911G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248430 | c.1917T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248448 | c.1935C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248457 | c.1944T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248472 | c.1959T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248496 | c.1983G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249375 | c.2862G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249381 | c.2868A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249459 | c.2946G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249474 | c.2961C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249486 | c.2973T>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249487 | c.2974_2976delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4249492 | c.2979C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249501 | c.2988C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249521 | p.Ala1003Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249525 | c.3012T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249529 | p.Ile1006Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249532 | p.Ala1007Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4249540 | c.3027C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249546 | c.3033G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249568 | p.Ser1019Asn | missense_variant | 1.0 | ethambutol | |
| embB | 4249573 | c.3060T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249594 | c.3081G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249607 | p.Thr1032Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249618 | c.3105C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249624 | c.3111C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249627 | c.3114G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249640 | c.3127T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249648 | c.3135G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249654 | c.3141C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249657 | c.3144C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249675 | c.3162C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267580 | c.1257G>A | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267592 | c.1245C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4269045 | c.-209G>C | upstream_gene_variant | 1.0 | ethambutol |
