Run ID: ERR4797588
Sample name:
Date: 2024-10-04T01:50:17.774516
Number of reads: 3648035
Percentage reads mapped: 75.47
Median coverage: 95.0
Strain: lineage3
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage3 | East-African-Indian | RD750 | 0.98 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Asp435Val | Assoc w R | |
isoniazid | katG | p.Ala172Thr | Uncertain significance | Mutation from literature |
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Leu359Ile | Uncertain significance | Mutation from literature | ||
p.Asp1024Asn | Uncertain significance | Mutation from literature | ||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761110 | p.Asp435Val | missense_variant | 0.77 | rifampicin | Assoc w R | |
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.35 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2155598 | p.Ala172Thr | missense_variant | 1.0 | isoniazid | Uncertain significance | Mutation from literature |
embB | 4247448 | p.His312Arg | missense_variant | 0.18 | ethambutol | Mutation from literature | |
embB | 4247588 | p.Leu359Ile | missense_variant | 0.16 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4249583 | p.Asp1024Asn | missense_variant | 0.88 | ethambutol | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 42 | c.42C>T | synonymous_variant | 0.14 | isoniazid | |
dnaA | 558 | c.558G>C | synonymous_variant | 0.17 | isoniazid | |
dnaA | 561 | c.561C>T | synonymous_variant | 0.17 | isoniazid | |
dnaA | 567 | c.567C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 591 | c.591C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 600 | c.600T>A | synonymous_variant | 0.19 | isoniazid | |
dnaA | 612 | c.612G>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 627 | c.627G>A | synonymous_variant | 0.27 | isoniazid | |
dnaA | 645 | c.645A>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 649 | c.649C>T | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 660 | c.660G>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 669 | c.669C>T | synonymous_variant | 0.24 | isoniazid | |
dnaA | 672 | c.672T>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 681 | c.681G>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 682 | c.682T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 720 | c.720G>A | synonymous_variant | 0.26 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.21 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805_807delTTGinsCTC | synonymous_variant | 0.26 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.25 | isoniazid | |
dnaA | 819 | c.819C>T | synonymous_variant | 0.25 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.27 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.25 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.18 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 942 | c.942C>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.2 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.21 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 969 | c.969G>A | synonymous_variant | 0.2 | isoniazid | |
dnaA | 975 | c.975G>T | synonymous_variant | 0.17 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>G | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 996 | c.996A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 999 | c.999C>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1041 | c.1041G>A | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.15 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.16 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.18 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 1311 | c.1311C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1320 | c.1320G>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1375 | c.1375T>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.18 | isoniazid | |
gyrB | 6238 | c.999G>A | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6415 | c.-887G>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6628 | c.-674C>T | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7123 | c.-179C>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | p.Ser629Thr | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7228 | c.-74C>T | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7234 | c.1995C>T | synonymous_variant | 0.14 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>A | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7562 | c.261C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7673 | c.372G>A | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7721 | c.420G>A | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7725 | c.424C>T | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7739 | c.438C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8579 | p.Asp426Glu | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8627 | c.1326C>A | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8708 | c.1407G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8750 | c.1449C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Ser | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.2 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8807 | c.1506C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.18 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>A | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9218 | c.1917C>T | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9293 | c.1992G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | c.2007C>T | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9312 | c.2011C>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9317 | c.2016G>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9365 | c.2064G>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13905 | c.-347G>T | upstream_gene_variant | 0.91 | isoniazid | |
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490935 | c.153C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490962 | c.180T>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490984 | p.Leu68Ile | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490987 | p.Leu69Met | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491001 | c.219G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491082 | c.300T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491083 | p.Val101Ile | missense_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491100 | c.318C>T | synonymous_variant | 0.31 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491173 | c.391C>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491302 | p.Ile174Val | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491307 | c.525C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491643 | c.861G>A | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491649 | c.867C>T | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491661 | c.879C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.18 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620688 | c.798G>C | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620710 | p.Val274Ile | missense_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657231 | p.Ile80Val | missense_variant | 0.19 | ethionamide | |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.22 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.22 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.19 | ethionamide | |
Rv0565c | 657327 | c.144C>G | synonymous_variant | 0.2 | ethionamide | |
Rv0565c | 657337 | p.Arg45Gln | missense_variant | 0.21 | ethionamide | Uncertain significance |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657347 | c.124A>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657356 | p.Ile39Val | missense_variant | 0.22 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.17 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.19 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.22 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.19 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.2 | ethionamide | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.18 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.16 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.16 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.22 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.24 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.25 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.27 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.3 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.29 | isoniazid | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.18 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.18 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.21 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.24 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.2 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.19 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 759746 | c.-61C>T | upstream_gene_variant | 0.98 | rifampicin | Not assoc w R |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760313 | c.507G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760340 | c.534G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760343 | c.537G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.29 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.27 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243His | missense_variant | 0.3 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760561 | c.757_758delCG | frameshift_variant | 0.31 | rifampicin | |
rpoB | 760567 | p.Ser254Trp | missense_variant | 0.3 | rifampicin | |
rpoB | 760568 | c.762_763insGC | frameshift_variant | 0.3 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.29 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.17 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761096 | c.1290G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761204 | c.1398C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761273 | c.1467T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761345 | c.1539G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.2 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.2 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761439 | p.Asp545Ser | missense_variant | 0.21 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.23 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.26 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761483 | c.1677G>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761504 | c.1698C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761564 | c.1758G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761689 | p.Ala628Glu | missense_variant | 0.81 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.16 | rifampicin | |
rpoB | 761834 | c.2028T>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.17 | rifampicin | |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.18 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.18 | rifampicin | |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoB | 762122 | c.2316C>T | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762158 | c.2352G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762248 | c.2442G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.17 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 762380 | c.-990T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762389 | c.-981G>A | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762434 | c.2628T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R |
rpoC | 762446 | c.-924C>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoB | 762486 | p.Pro894Ala | missense_variant | 0.2 | rifampicin | |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.19 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.17 | rifampicin | Uncertain significance |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.28 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762836 | c.3030C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 763034 | c.-336C>A | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 763187 | c.-183C>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.24 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763504 | c.135C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763657 | c.288G>A | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763729 | c.360G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763768 | c.399C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.36 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.3 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.28 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.3 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763951 | c.582G>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763960 | c.591T>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.43 | rifampicin | |
rpoC | 763996 | c.627T>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.43 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764110 | c.741C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764194 | p.Glu275Asp | missense_variant | 0.41 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764287 | c.918C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764293 | c.924G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764344 | c.975C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764410 | c.1041G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 764585 | c.1216_1218delCTCinsTTG | synonymous_variant | 0.43 | rifampicin | |
rpoC | 764611 | c.1242G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764749 | c.1380G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764983 | c.1614T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765016 | c.1647C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.32 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765752 | p.Asp795Ser | missense_variant | 0.25 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765947 | c.2578T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.24 | rifampicin | |
rpoC | 766061 | p.Val898Leu | missense_variant | 0.2 | rifampicin | |
rpoC | 766081 | c.2712T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.18 | rifampicin | |
rpoC | 766258 | c.2889T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.23 | rifampicin | |
rpoC | 766279 | c.2910C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.22 | rifampicin | |
rpoC | 766300 | c.2931C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766321 | c.2952C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766369 | c.3000C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766387 | c.3018C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766402 | c.3033C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766471 | c.3102G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.32 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766579 | c.3210C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.25 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.28 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766633 | c.3264G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766651 | c.3282T>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766942 | c.3573C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 767035 | c.3666G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.42 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.32 | rifampicin | |
rpoC | 767152 | c.3783T>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.28 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.2 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781605 | p.Ile16Val | missense_variant | 0.17 | streptomycin | Uncertain significance |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.17 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.31 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.3 | streptomycin | Uncertain significance |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.4 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.34 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.21 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.19 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.24 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.18 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.18 | linezolid | |
rplC | 800875 | p.Val23Ile | missense_variant | 0.16 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.18 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800939 | p.Arg44His | missense_variant | 0.15 | linezolid | |
rplC | 800967 | c.159C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.17 | linezolid | Not assoc w R - Interim |
rplC | 801195 | c.387G>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.17 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.19 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.17 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.17 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.17 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.2 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.22 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.23 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.19 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.2 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.23 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.17 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.17 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.19 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303866 | p.Glu312Asp | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.27 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305063 | c.2133G>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305066 | c.2136T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305069 | c.2139G>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305075 | c.2145T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305078 | c.2148A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
atpE | 1461089 | c.45G>C | synonymous_variant | 0.21 | bedaquiline | |
atpE | 1461097 | p.Ala18Gly | missense_variant | 0.2 | bedaquiline | |
atpE | 1461101 | c.57T>C | synonymous_variant | 0.2 | bedaquiline | |
atpE | 1461107 | c.63C>G | synonymous_variant | 0.19 | bedaquiline | |
atpE | 1461113 | c.69C>T | synonymous_variant | 0.25 | bedaquiline | |
atpE | 1461132 | p.Val30Ile | missense_variant | 0.3 | bedaquiline | |
atpE | 1461149 | c.105T>G | synonymous_variant | 0.31 | bedaquiline | |
atpE | 1461150 | p.Ile36Val | missense_variant | 0.31 | bedaquiline | |
atpE | 1461158 | c.114T>G | synonymous_variant | 0.31 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 0.31 | bedaquiline | Uncertain significance |
atpE | 1461170 | c.126A>G | synonymous_variant | 0.3 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.28 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.27 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.3 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 0.18 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.27 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.27 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.24 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474044 | n.387C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474964 | n.1307T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475028 | n.1371G>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476717 | n.3060C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
inhA | 1673568 | c.-634C>G | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1673580 | c.-622T>G | upstream_gene_variant | 0.22 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673591 | c.-611C>T | upstream_gene_variant | 0.18 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673596 | c.-606A>G | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673602 | c.-600C>T | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673615 | c.-587_-586delAAinsTG | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673633 | c.-569G>A | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1673637 | c.-565C>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673641 | c.-561G>A | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673985 | c.-217C>A | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674006 | c.-196T>G | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674018 | c.-184G>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674021 | c.-181G>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674033 | c.-169T>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674037 | c.-165_-164delCAinsGC | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674042 | c.-160G>T | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674049 | c.-153_-151delCAAinsGAC | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674054 | c.-148T>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674060 | c.-142A>G | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674063 | c.-139G>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674079 | c.-123C>G | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833877 | c.336C>T | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834096 | c.555G>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834333 | c.792C>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.23 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.18 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.17 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.17 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2064912 | c.-184A>G | upstream_gene_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064915 | c.-187G>C | upstream_gene_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064933 | c.-205A>G | upstream_gene_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064936 | c.-208C>G | upstream_gene_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064942 | c.-214G>A | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 0.19 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 0.17 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.18 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101939 | c.1104A>G | synonymous_variant | 0.19 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155691 | c.421T>C | synonymous_variant | 0.19 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 0.21 | isoniazid | |
katG | 2155704 | c.408C>G | synonymous_variant | 0.23 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.23 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.23 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.23 | isoniazid | |
katG | 2155740 | p.Gly124Gln | missense_variant | 0.23 | isoniazid | |
katG | 2155743 | c.369G>C | synonymous_variant | 0.23 | isoniazid | |
katG | 2155785 | c.327T>C | synonymous_variant | 0.17 | isoniazid | |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
PPE35 | 2169599 | p.Asn338Lys | missense_variant | 1.0 | pyrazinamide | |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
pncA | 2289047 | c.195C>T | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R |
pncA | 2289365 | c.-125delC | upstream_gene_variant | 1.0 | pyrazinamide | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.19 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.16 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.17 | isoniazid | |
ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 0.99 | isoniazid | Not assoc w R |
ahpC | 2726116 | c.-77T>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
ahpC | 2726579 | c.387T>C | synonymous_variant | 0.19 | isoniazid | |
ahpC | 2726591 | c.399C>G | synonymous_variant | 0.24 | isoniazid | |
ahpC | 2726593 | p.Val134Ala | missense_variant | 0.24 | isoniazid | |
ahpC | 2726600 | c.408T>C | synonymous_variant | 0.24 | isoniazid | |
ahpC | 2726601 | p.Ile137Leu | missense_variant | 0.25 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.19 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.19 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
folC | 2747314 | c.285A>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
Rv2477c | 2782498 | c.1545C>T | synonymous_variant | 0.99 | kanamycin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.15 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782894 | c.1149C>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.34 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.29 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.35 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>A | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.27 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.28 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.28 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.16 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783602 | c.441G>A | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.25 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784414 | c.-372A>G | upstream_gene_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065988 | c.204A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066003 | c.189C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066009 | c.183G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066024 | c.168T>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066066 | c.126T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067249 | p.Thr233Ser | missense_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067252 | p.Val232Met | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067462 | c.484C>T | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067490 | p.Ala152Glu | missense_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067510 | c.436C>T | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067559 | c.387C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067577 | c.369G>A | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067598 | c.348C>T | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067601 | p.Arg115His | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067631 | c.315C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067691 | p.Ile85Leu | missense_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067736 | c.210C>T | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067877 | c.69G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074034 | c.438T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074079 | c.393G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074097 | c.375C>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3074100 | p.Asp124Asn | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3074127 | c.345G>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3074130 | c.342G>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074154 | c.318T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074157 | c.315C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074160 | c.312A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074163 | p.Ala103Thr | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3074172 | c.300G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074175 | c.297A>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074181 | c.291A>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074187 | c.285T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3083 | 3449158 | p.Ser219Ala | missense_variant | 1.0 | ethionamide | Uncertain significance |
lpqB | 3624701 | c.210T>C | synonymous_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624704 | c.207G>C | synonymous_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624707 | c.204G>C | synonymous_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624749 | c.162G>A | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624755 | c.154_156delTTAinsCTG | synonymous_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3625087 | p.Ala509Ser | missense_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625093 | p.Glu507Asp | missense_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625135 | c.1479A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625149 | p.Val489Ile | missense_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625165 | c.-255G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625206 | p.Ser470Ala | missense_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.31 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.32 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625876 | c.738G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626900 | c.-287G>A | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626945 | c.-332C>T | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627146 | c.204C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTA | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
fbiA | 3640346 | c.-196delA | upstream_gene_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.24 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.24 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.27 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.25 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.28 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.27 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3877962 | c.546G>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878046 | c.462T>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878058 | c.450G>T | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.16 | rifampicin | Uncertain significance |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.2 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878310 | c.198G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878364 | c.144A>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878463 | c.45C>A | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 0.18 | rifampicin | Uncertain significance |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>A | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878838 | c.-331A>T | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoA | 3878890 | c.-383C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878896 | c.-389G>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.21 | rifampicin | Uncertain significance |
rpoA | 3878932 | c.-425G>A | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.22 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.22 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.24 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.17 | rifampicin | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4038460 | p.Leu749Met | missense_variant | 0.23 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038498 | p.Ser736Asn | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.25 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.24 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038857 | c.1848C>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.28 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039336 | c.1369C>T | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039382 | c.1323C>A | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.21 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039480 | c.1225C>A | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>G | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039484 | c.1221T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.3 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.3 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039805 | c.900C>T | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040215 | p.Ser164Thr | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040228 | c.477G>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040231 | c.474C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040444 | c.261C>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040492 | c.213G>A | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.18 | pyrazinamide | |
panD | 4044737 | c.-456T>C | upstream_gene_variant | 0.19 | pyrazinamide | |
panD | 4044746 | c.-467_-465delGTGinsATC | upstream_gene_variant | 0.18 | pyrazinamide | |
panD | 4044752 | c.-471T>C | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044758 | c.-477C>T | upstream_gene_variant | 0.19 | pyrazinamide | |
panD | 4044781 | c.-500C>T | upstream_gene_variant | 0.15 | pyrazinamide | |
panD | 4044791 | c.-510G>C | upstream_gene_variant | 0.17 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 0.19 | pyrazinamide | |
panD | 4044823 | c.-542G>C | upstream_gene_variant | 0.19 | pyrazinamide | |
panD | 4044844 | c.-563T>C | upstream_gene_variant | 0.23 | pyrazinamide | |
panD | 4044848 | c.-567T>A | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044854 | c.-573A>G | upstream_gene_variant | 0.19 | pyrazinamide | |
panD | 4044860 | c.-579C>G | upstream_gene_variant | 0.17 | pyrazinamide | |
panD | 4044872 | c.-591C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
panD | 4045001 | c.-720G>C | upstream_gene_variant | 0.17 | pyrazinamide | |
panD | 4045019 | c.-738G>C | upstream_gene_variant | 0.18 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.17 | pyrazinamide | |
panD | 4045070 | c.-789C>T | upstream_gene_variant | 0.15 | pyrazinamide | |
glpK | 4138622 | c.1134C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
glpK | 4139537 | c.219G>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139541 | p.Ile72Thr | missense_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139545 | c.211T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139552 | p.Ala68Ser | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139561 | c.195G>A | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.44 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
glpK | 4139588 | c.168G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139601 | p.Arg52Gln | missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139615 | c.141G>A | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
glpK | 4139651 | p.His35Glu | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4240699 | c.837C>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embC | 4240726 | c.864G>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.21 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.27 | ethambutol | |
embC | 4240828 | c.966G>A | synonymous_variant | 0.28 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.28 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.29 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.29 | ethambutol | |
embC | 4240873 | c.1011C>G | synonymous_variant | 0.27 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.28 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.28 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.27 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.24 | ethambutol | Not assoc w R |
embC | 4240898 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.23 | ethambutol | |
embC | 4240903 | c.1041C>G | synonymous_variant | 0.25 | ethambutol | |
embC | 4240911 | p.Ala350Val | missense_variant | 0.26 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4240924 | c.1062C>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4240936 | c.1074A>G | synonymous_variant | 0.27 | ethambutol | |
embC | 4240945 | c.1083T>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4241047 | c.1185C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.18 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.24 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.31 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.29 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.28 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.26 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4241206 | c.1344G>C | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embC | 4241218 | c.1356G>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 0.16 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4241488 | c.1626G>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4241496 | p.Ala545Gly | missense_variant | 0.19 | ethambutol | |
embC | 4241500 | c.1638A>C | synonymous_variant | 0.18 | ethambutol | |
embC | 4241501 | p.Ser547Thr | missense_variant | 0.18 | ethambutol | |
embC | 4241506 | c.1644G>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4241518 | c.1656A>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241521 | c.1659T>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embC | 4241530 | c.1668C>A | synonymous_variant | 0.23 | ethambutol | |
embC | 4241536 | c.1674A>G | synonymous_variant | 0.21 | ethambutol | |
embC | 4241539 | c.1677T>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embC | 4241545 | c.1683T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4241548 | c.1686T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4241551 | c.1689A>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.23 | ethambutol | |
embC | 4241572 | c.1710C>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4241578 | c.1716G>C | synonymous_variant | 0.21 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4241587 | c.1725C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241591 | p.Leu577Val | missense_variant | 0.2 | ethambutol | |
embC | 4241611 | c.1749G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4242075 | p.Arg738Gln | missense_variant | 0.97 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.98 | ethambutol | Not assoc w R |
embA | 4242748 | c.-485A>G | upstream_gene_variant | 0.17 | ethambutol | |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.16 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.18 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.26 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.27 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.26 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.26 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.27 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.24 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.21 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 0.2 | ethambutol | |
embA | 4245222 | p.Tyr664Gln | missense_variant | 0.2 | ethambutol | |
embA | 4245248 | c.2016G>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245257 | c.2025A>G | synonymous_variant | 0.23 | ethambutol | |
embA | 4245263 | c.2031A>G | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embA | 4245282 | p.Ile684Val | missense_variant | 0.16 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 0.16 | ethambutol | |
embB | 4247425 | c.912G>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4247434 | c.921C>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
embB | 4247440 | c.927C>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4247446 | c.933C>T | synonymous_variant | 0.17 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 0.17 | ethambutol | |
embB | 4247579 | p.Ala356Phe | missense_variant | 0.16 | ethambutol | |
embB | 4247776 | c.1263G>T | synonymous_variant | 0.17 | ethambutol | |
embB | 4247797 | c.1284C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247800 | c.1287A>T | synonymous_variant | 0.21 | ethambutol | |
embB | 4247803 | c.1290G>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247815 | c.1302C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247819 | p.Val436Ile | missense_variant | 0.21 | ethambutol | Uncertain significance |
embB | 4247830 | c.1317A>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4247836 | c.1323A>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4247839 | c.1326G>C | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4247866 | c.1353G>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4247875 | c.1362G>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 0.24 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embB | 4247893 | c.1380C>T | synonymous_variant | 0.23 | ethambutol | |
embB | 4247899 | p.Met462Ile | missense_variant | 0.23 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247914 | c.1401G>C | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embB | 4248035 | p.Val508Ile | missense_variant | 0.21 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 0.2 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.2 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.21 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.17 | ethambutol | |
embB | 4248208 | c.1695C>T | synonymous_variant | 0.16 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.27 | ethambutol | |
embB | 4248316 | c.1803C>G | synonymous_variant | 0.28 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.29 | ethambutol | |
embB | 4248343 | c.1830G>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4248355 | c.1842A>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248358 | c.1845C>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4248361 | c.1848A>G | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
embB | 4248362 | p.Ser617Ala | missense_variant | 0.18 | ethambutol | |
embB | 4248386 | c.1873C>A | synonymous_variant | 0.16 | ethambutol | |
embB | 4249469 | p.Leu986Met | missense_variant | 0.19 | ethambutol | |
ubiA | 4269436 | p.Ala133Gly | missense_variant | 0.17 | ethambutol | |
ubiA | 4269448 | p.Val129Ala | missense_variant | 0.17 | ethambutol | |
aftB | 4269458 | c.-622C>T | upstream_gene_variant | 0.17 | ethambutol | |
aftB | 4269471 | c.-635C>G | upstream_gene_variant | 0.16 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |