Run ID: ERR3799304
Sample name:
Date: 2024-10-05T08:31:54.022099
Number of reads: 3164986
Percentage reads mapped: 69.88
Median coverage: 151.0
Strain: lineage6.1.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage6.1.1 | West-Africa 2 | RD702 | 0.99 |
lineage6 | West-Africa 2 | RD702 | 0.96 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
embB | 4247580 | p.Ala356Val | missense_variant | 0.26 | ethambutol | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrB | 6446 | p.Ala403Ser | missense_variant | 0.96 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7502 | c.201C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7526 | c.225G>T | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7626 | c.325C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7643 | c.342C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.2 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8360 | c.1059G>A | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8372 | c.1071G>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8392 | p.Tyr364Phe | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8402 | p.Asp367Glu | missense_variant | 0.21 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8408 | c.1107A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8417 | c.1116C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8426 | c.1125G>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8429 | c.1128C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8447 | c.1146C>A | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8450 | c.1149G>A | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8492 | c.1191G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8493 | p.Leu398Phe | missense_variant | 0.78 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8531 | c.1230G>T | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8535 | p.Glu412Gln | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8555 | c.1254G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8585 | c.1284C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>T | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8694 | c.1393C>T | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8717 | c.1416C>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8720 | c.1419G>A | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8765 | p.Asp488Glu | missense_variant | 0.31 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.31 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8789 | c.1488C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8792 | c.1491G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8798 | c.1497C>T | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8813 | p.Asp504Glu | missense_variant | 0.3 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8840 | c.1539C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8888 | c.1587C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8924 | c.1623C>T | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8930 | c.1629C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8936 | c.1635G>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9003 | c.1702C>T | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9038 | c.1737C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9062 | c.1761C>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9074 | c.1773G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9095 | c.1794C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9101 | c.1800A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9104 | c.1803C>A | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9110 | c.1809G>A | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9128 | c.1827C>A | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9147 | p.Gly616Ser | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9167 | c.1866C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9183 | p.Arg628Lys | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9236 | c.1935G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9248 | c.1947G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9266 | c.1965C>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9287 | c.1986G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9315 | c.2014C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9326 | c.2025G>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13460 | c.99T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13482 | p.Ala26Val | missense_variant | 1.0 | isoniazid | Not assoc w R |
fgd1 | 490971 | c.189A>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490983 | c.201G>A | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490988 | p.Leu69Gln | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490995 | c.213C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491016 | c.234C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491094 | c.312C>T | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491110 | p.Ala110Ser | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491115 | c.333G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491136 | c.354C>T | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491168 | p.Phe129Tyr | missense_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491668 | p.Lys296Glu | missense_variant | 1.0 | pretomanid | |
delamanid | Uncertain significance | |||||
clofazimine | Uncertain significance | |||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 656432 | p.Gly347Ser | missense_variant | 0.95 | ethionamide | Uncertain significance |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760274 | c.468G>A | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760295 | c.489C>T | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760358 | c.552C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.26 | rifampicin | |
rpoB | 760403 | c.597C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760412 | c.606C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760457 | c.651C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760472 | c.666C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760478 | c.672C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760493 | c.687C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760520 | c.714C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760526 | c.720G>A | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.26 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.27 | rifampicin | |
rpoB | 760601 | c.795C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760622 | c.816C>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760649 | c.843G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760748 | c.942C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.3 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.31 | rifampicin | |
rpoB | 760855 | p.Thr350Met | missense_variant | 0.69 | rifampicin | |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760916 | c.1110C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760937 | c.1131G>A | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760969 | p.Ser388Leu | missense_variant | 0.75 | rifampicin | Not assoc w R |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760982 | c.1176G>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760985 | c.1179G>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760991 | c.1185G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761006 | c.1200C>T | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761096 | c.1290G>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327_1329delTTGinsCTC | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761192 | c.1386C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761240 | c.1434C>T | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761345 | c.1539G>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.22 | rifampicin | |
rpoB | 761374 | p.Val523Glu | missense_variant | 0.22 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761432 | c.1626C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.22 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.22 | rifampicin | |
rpoB | 761465 | c.1659G>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761471 | c.1665C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761477 | c.1671C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761504 | c.1698C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761558 | c.1752C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>A | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761666 | c.1860G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761723 | p.Glu639Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.2 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.21 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.2 | rifampicin | |
rpoB | 761828 | c.2022C>T | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.2 | rifampicin | |
rpoB | 761921 | c.2115C>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761930 | c.2124G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762038 | c.2232C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762047 | c.2241G>A | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.35 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762134 | c.2328C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>T | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.32 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 762281 | c.2475G>A | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762341 | c.2535G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.3 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762431 | c.2625C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762441 | c.2635C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762491 | c.2685T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.23 | rifampicin | Uncertain significance |
rpoC | 762902 | c.-468C>T | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762917 | c.-453C>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763050 | c.-320C>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 763082 | c.3276C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoC | 763205 | c.-165G>T | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763726 | c.357C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763771 | c.402C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763836 | p.Ala156Val | missense_variant | 0.31 | rifampicin | |
rpoC | 763851 | p.Ala161Gly | missense_variant | 0.28 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.29 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.3 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763891 | c.522G>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763919 | c.550C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763951 | c.582G>A | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763963 | c.594C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.32 | rifampicin | |
rpoC | 763972 | c.603C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.33 | rifampicin | |
rpoC | 764044 | c.675T>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764159 | c.790C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764167 | c.798G>A | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.29 | rifampicin | |
rpoC | 764215 | c.846A>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764218 | c.849C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764242 | c.873C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764245 | c.876C>A | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764246 | c.877_879delCTCinsTTG | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764263 | c.894G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764293 | c.924G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764320 | c.951C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764605 | c.1236G>A | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764686 | c.1317C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764696 | c.1327C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764746 | c.1377G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764782 | c.1413C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764803 | c.1434C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R |
rpoC | 765370 | c.2001G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoC | 765391 | c.2022C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765406 | c.2037G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765452 | p.Ala695Ser | missense_variant | 0.31 | rifampicin | |
rpoC | 765466 | c.2097C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765493 | c.2124G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765517 | c.2148C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765571 | c.2202C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765622 | p.Glu751Asp | missense_variant | 0.33 | rifampicin | |
rpoC | 765625 | c.2256C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765728 | p.Gln787Lys | missense_variant | 0.3 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765752 | p.Asp795Ser | missense_variant | 0.3 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765790 | c.2421C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765934 | c.2565C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766012 | c.2643C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766231 | c.2862T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766402 | c.3033C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.29 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766585 | c.3216T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.3 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766660 | c.3291G>A | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766700 | c.3331C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766733 | c.3364C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766741 | c.3372G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766798 | c.3429C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 766883 | p.Ser1172Ala | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766903 | c.3534C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.34 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.28 | rifampicin | |
rpoC | 767158 | c.3789T>A | synonymous_variant | 0.25 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.22 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781832 | c.273T>G | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781835 | c.276T>C | synonymous_variant | 0.21 | streptomycin | Not assoc w R - Interim |
rpsL | 781859 | c.300T>G | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781883 | c.324G>A | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781886 | c.327C>T | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.24 | streptomycin | Uncertain significance |
rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 0.25 | streptomycin | |
rplC | 800232 | c.-577G>T | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800714 | c.-95C>T | upstream_gene_variant | 0.19 | linezolid | |
rplC | 801255 | c.447C>A | synonymous_variant | 0.2 | linezolid | |
rplC | 801285 | c.477G>A | synonymous_variant | 0.21 | linezolid | |
rplC | 801330 | c.522G>T | synonymous_variant | 0.19 | linezolid | |
rplC | 801333 | c.525G>C | synonymous_variant | 0.19 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 1.0 | pretomanid | |
delamanid | Uncertain significance | |||||
clofazimine | Uncertain significance | |||||
fbiC | 1303629 | c.699C>T | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303662 | c.732C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304610 | c.1680C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304797 | p.Ala623Thr | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304823 | c.1893C>T | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304868 | c.1938G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304872 | c.1942_1943delAGinsTC | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304934 | c.2004C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304955 | c.2025G>A | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364790 | c.378T>C | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364799 | c.387G>C | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364802 | c.390C>A | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364820 | c.408A>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364847 | c.435G>C | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364868 | c.456T>C | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364871 | c.459C>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364883 | c.471G>A | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364889 | c.477A>G | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364892 | c.480C>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364913 | c.501C>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364925 | c.513C>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364928 | c.516C>T | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364984 | p.Ala191Asp | missense_variant | 0.18 | pyrazinamide | |
Rv1258c | 1406685 | p.Val219Ala | missense_variant | 1.0 | streptomycin | Uncertain significance |
pyrazinamide | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
embR | 1416633 | p.Leu239Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
embR | 1417554 | c.-207C>G | upstream_gene_variant | 1.0 | ethambutol | |
atpE | 1461251 | c.207G>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472460 | n.615T>C | non_coding_transcript_exon_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472463 | n.618G>C | non_coding_transcript_exon_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.22 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472686 | n.841G>A | non_coding_transcript_exon_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.24 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473797 | n.140G>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1473831 | n.174G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1473918 | n.261C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1473994 | n.337C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474011 | n.354G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474018 | n.361G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1474030 | n.373G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474061 | n.404T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474100 | n.443C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474110 | n.453A>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474945 | n.1288C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474952 | n.1296_1300delCATCC | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474962 | n.1305T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474967 | n.1311_1315delGGGTG | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474991 | n.1334T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474995 | n.1338T>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475005 | n.1348C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475007 | n.1350C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475018 | n.1361G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475027 | n.1370G>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475028 | n.1371G>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475404 | n.1747A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475453 | n.1796T>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475487 | n.1830C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475605 | n.1948A>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475637 | n.1980T>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475760 | n.2103C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475999 | n.2342G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476077 | n.2420T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1674434 | p.Val78Ala | missense_variant | 0.96 | isoniazid | Not assoc w R |
ethionamide | Uncertain significance | |||||
inhA | 1674729 | c.528G>A | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674745 | p.Tyr182Asp | missense_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674765 | c.564C>T | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674777 | c.576C>A | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674792 | c.591G>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674820 | c.619_621delCTCinsTTG | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674876 | c.675C>G | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674888 | c.687C>T | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833613 | c.72C>A | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833703 | c.162C>T | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833760 | c.219C>T | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833859 | c.318C>T | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833895 | c.354G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833970 | c.429G>A | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.25 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834231 | c.690T>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834297 | c.756C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834336 | c.795C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834357 | c.816T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834396 | c.855G>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834423 | c.882G>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834456 | c.915T>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834477 | c.936C>T | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834519 | c.978G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834603 | c.1062G>A | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834612 | c.1071G>A | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834654 | c.1113G>A | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834699 | p.Glu386Asp | missense_variant | 0.2 | pyrazinamide | |
tsnR | 1853370 | c.-236G>T | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853375 | c.-231G>A | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853393 | c.-213C>T | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853395 | c.-211T>C | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1854026 | p.Gly141Arg | missense_variant | 0.99 | linezolid | Uncertain significance |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2062922 | p.Ile603Val | missense_variant | 0.99 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
bacA | 2063121 | c.1608A>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
katG | 2154286 | p.Met609Thr | missense_variant | 1.0 | isoniazid | Uncertain significance |
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155503 | c.609C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.21 | isoniazid | |
kasA | 2517965 | c.-150C>T | upstream_gene_variant | 0.19 | isoniazid | |
kasA | 2518132 | c.18C>T | synonymous_variant | 0.99 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518573 | c.459G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.27 | isoniazid | |
kasA | 2518582 | c.468G>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518583 | p.Gln157Glu | missense_variant | 0.28 | isoniazid | |
kasA | 2518594 | c.480C>T | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518597 | c.483C>G | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518606 | c.492G>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.36 | isoniazid | |
kasA | 2518636 | c.522C>A | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518639 | c.525G>C | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518645 | c.531G>C | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518651 | c.537C>G | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518681 | c.567C>T | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518687 | p.Asp191Glu | missense_variant | 0.36 | isoniazid | |
kasA | 2518693 | c.579C>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518717 | c.603C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518723 | c.609G>A | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518735 | c.621C>T | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518768 | c.654C>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518795 | c.681C>A | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518798 | c.684G>C | synonymous_variant | 0.24 | isoniazid | |
Rv2477c | 2783419 | c.624G>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783427 | p.Pro206Ala | missense_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | ||||||
Rv2477c | 2783431 | c.612C>T | synonymous_variant | 0.21 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783437 | c.606G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783632 | c.411C>G | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783743 | c.300C>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783788 | c.255T>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783794 | c.249G>A | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783806 | c.237G>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783827 | c.216C>T | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783836 | c.207C>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783857 | c.186C>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>T | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2752c | 3066384 | c.-193G>A | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066387 | c.-196G>A | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066399 | c.-210_-208delATTinsGTC | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066402 | c.-211C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066420 | c.-229C>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066423 | c.-232C>T | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066426 | c.-235T>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066429 | c.-238G>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066437 | c.-246G>A | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066459 | c.-268T>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066465 | c.-276_-274delGGGinsAGC | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066474 | c.-283G>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066477 | c.-286C>T | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066480 | c.-291_-289delGCCinsTCT | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066483 | c.-292T>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066513 | c.-322C>G | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066527 | c.-336C>T | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066543 | c.-352C>A | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066560 | c.-369C>T | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066567 | c.-376C>A | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066597 | c.-406C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyA | 3073854 | c.618C>T | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073889 | p.Ser195Ala | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3073905 | c.567C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
ald | 3086728 | c.-92C>T | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3087084 | c.266delA | frameshift_variant | 0.99 | cycloserine | |
Rv3236c | 3612143 | p.Arg325His | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
lpqB | 3624350 | c.561G>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624486 | p.Asp142Gly | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625147 | c.-237C>G | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625198 | c.-288C>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625207 | c.-297C>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625213 | c.-303C>T | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625234 | c.-324G>A | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625243 | c.-333T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625251 | c.-341C>T | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625255 | c.-345T>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625699 | c.915C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625717 | c.-807C>T | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625747 | c.867G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.24 | rifampicin | Uncertain significance |
bedaquiline | ||||||
lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625783 | c.-873C>T | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626924 | c.-311G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626927 | c.-314G>A | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626933 | c.-320C>T | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626996 | c.-383G>A | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627023 | c.-410C>G | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627137 | c.-526_-524delTTGinsCTA | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627143 | c.-530G>C | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627187 | c.163T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627212 | c.-599C>T | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>G | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627239 | c.111C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877557 | c.951C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877587 | c.921A>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.29 | rifampicin | |
rpoA | 3877617 | c.891G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877638 | c.870T>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877656 | c.852T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.31 | rifampicin | |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877685 | c.823C>T | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877758 | c.750G>C | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3877815 | c.693C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3877830 | c.678C>T | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877851 | c.657C>T | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877865 | c.643C>T | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877887 | c.621G>C | synonymous_variant | 0.42 | rifampicin | |
rpoA | 3877900 | p.Ser203Thr | missense_variant | 0.4 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.4 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoA | 3877968 | c.540C>G | synonymous_variant | 0.41 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878025 | c.483C>T | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878043 | c.465G>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878046 | c.462T>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878082 | c.426T>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878097 | c.411G>A | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878145 | c.363C>G | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878166 | c.342C>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878184 | c.324C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3878205 | c.303T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3878229 | c.279C>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878256 | c.252G>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878264 | p.Ser82Gly | missense_variant | 0.37 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.35 | rifampicin | Uncertain significance |
rpoA | 3878295 | c.213A>G | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878364 | c.144A>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3878384 | c.124C>T | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878391 | c.117T>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878418 | c.90C>T | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878458 | p.Asn17Ser | missense_variant | 0.35 | rifampicin | |
rpoA | 3878471 | p.Val13Leu | missense_variant | 0.35 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.35 | rifampicin | |
rpoA | 3878484 | c.24C>A | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878490 | c.18C>A | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878496 | c.12A>T | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878713 | c.-206G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.31 | rifampicin | Uncertain significance |
rpoA | 3878761 | c.-254G>A | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3878776 | c.-269G>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878779 | c.-274_-272delATCinsGTT | upstream_gene_variant | 0.28 | rifampicin | |
rpoA | 3878788 | c.-281G>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3878803 | c.-296G>C | upstream_gene_variant | 0.29 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoA | 3878836 | c.-329G>C | upstream_gene_variant | 0.31 | rifampicin | Uncertain significance |
rpoA | 3878842 | c.-335G>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878869 | c.-362G>C | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.32 | rifampicin | Uncertain significance |
rpoA | 3878881 | c.-374C>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878894 | c.-387A>G | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.36 | rifampicin | Uncertain significance |
rpoA | 3878923 | c.-417_-416delGCinsCG | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.39 | rifampicin | Uncertain significance |
rpoA | 3878953 | c.-446C>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.36 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.35 | rifampicin | Uncertain significance |
rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.28 | rifampicin | Uncertain significance |
rpoA | 3879001 | c.-494C>T | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879037 | c.-530G>A | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3879049 | c.-542A>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.24 | rifampicin | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038809 | c.1896G>A | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038875 | c.1830C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038893 | c.1812C>T | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038902 | c.1803C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039025 | c.1680C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>T | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>A | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039119 | c.1585_1586delTCinsAG | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.31 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039190 | c.1515C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039193 | c.1512C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039223 | c.1482C>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039238 | c.1467C>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039243 | c.1462C>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039259 | c.1446G>A | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039262 | c.1443C>T | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039268 | c.1437C>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039304 | c.1401G>A | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039319 | p.Ala462Thr | missense_variant | 0.26 | pyrazinamide | |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.25 | pyrazinamide | |
clpC1 | 4039361 | c.1344C>A | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039382 | c.1323C>T | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>A | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.24 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039472 | c.1233G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039484 | c.1221T>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039508 | c.1197G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039526 | c.1179G>A | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039532 | c.1173C>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039553 | c.1152C>A | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.33 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039583 | c.1122C>T | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039670 | c.1035G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039739 | c.966C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039748 | c.957G>A | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039787 | c.916_918delTCGinsAGC | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039796 | c.909C>T | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039805 | c.900C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039943 | c.762G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039964 | c.741C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040000 | c.705C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040015 | c.690G>A | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040090 | p.Ser205Thr | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040195 | c.510G>T | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040200 | c.505T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040204 | c.501G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040207 | c.498T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040228 | c.477G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040231 | c.474C>T | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4040309 | c.396C>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4040348 | c.357G>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040419 | c.286C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040456 | c.249C>T | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040462 | c.243C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040486 | c.219G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040495 | c.210C>A | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040525 | c.180C>T | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040573 | c.132T>A | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040600 | c.103_105delTTAinsCTG | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.29 | pyrazinamide | |
glpK | 4138377 | p.Val460Ala | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
glpK | 4138568 | c.1188A>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138574 | c.1182G>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138583 | c.1173G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138631 | c.1125C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138643 | c.1113A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138646 | c.1110G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138681 | p.Met359Val | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138682 | c.1074C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138702 | p.Gln352Glu | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138703 | c.1053C>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138706 | c.1050C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138714 | p.Ala348Ser | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138715 | c.1041G>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138751 | c.1005T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139183 | c.572dupG | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
embC | 4240671 | p.Thr270Ile | missense_variant | 0.99 | ethambutol | Not assoc w R |
embC | 4241452 | c.1590G>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4241455 | c.1593C>T | synonymous_variant | 0.2 | ethambutol | |
embC | 4241461 | c.1599C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241623 | c.1761C>G | synonymous_variant | 0.17 | ethambutol | |
embC | 4241843 | p.Leu661Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4243570 | p.Thr113Arg | missense_variant | 1.0 | ethambutol | Uncertain significance |
embA | 4244220 | c.988C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4244379 | p.Pro383Ser | missense_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4245078 | p.Trp616Gly | missense_variant | 0.21 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.22 | ethambutol | |
embA | 4245093 | p.Ile621Val | missense_variant | 0.22 | ethambutol | Uncertain significance |
embA | 4245125 | c.1893G>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.24 | ethambutol | |
embA | 4245183 | c.1951C>T | synonymous_variant | 0.21 | ethambutol | |
embA | 4245186 | p.Thr652Ala | missense_variant | 0.21 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.21 | ethambutol | |
embA | 4245223 | p.Tyr664Phe | missense_variant | 0.2 | ethambutol | |
embB | 4246864 | c.351C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4247470 | c.957T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247500 | c.987C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247506 | c.993C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247527 | c.1014G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4247550 | p.Ala346Asp | missense_variant | 0.26 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.27 | ethambutol | |
embB | 4247566 | c.1053C>G | synonymous_variant | 0.28 | ethambutol | |
embB | 4247572 | c.1059A>C | synonymous_variant | 0.27 | ethambutol | |
embB | 4247590 | c.1077A>G | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
embB | 4247629 | c.1116C>G | synonymous_variant | 0.25 | ethambutol | |
embB | 4247632 | c.1119C>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4247638 | c.1125G>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4248118 | c.1605T>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4248127 | c.1614G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4248133 | c.1620C>A | synonymous_variant | 0.26 | ethambutol | |
embB | 4248139 | c.1626C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4248146 | p.Ile545Leu | missense_variant | 0.26 | ethambutol | |
embB | 4248149 | p.Thr546Ser | missense_variant | 0.26 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embB | 4248161 | c.1648C>T | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embB | 4248169 | c.1656C>A | synonymous_variant | 0.29 | ethambutol | |
embB | 4248190 | c.1677G>C | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
embB | 4248200 | p.Ile563Val | missense_variant | 0.25 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.25 | ethambutol | Uncertain significance |
embB | 4248211 | c.1698G>A | synonymous_variant | 0.25 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4248241 | c.1728C>T | synonymous_variant | 0.25 | ethambutol | |
embB | 4248277 | c.1764G>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248631 | c.2118G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
ubiA | 4269351 | c.483C>T | synonymous_variant | 0.92 | ethambutol | Not assoc w R |
ubiA | 4269387 | p.Glu149Asp | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269522 | c.312C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269606 | c.228T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ethA | 4326465 | p.Ile337Val | missense_variant | 0.99 | ethionamide | Uncertain significance |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4408034 | p.Glu57Lys | missense_variant | 1.0 | streptomycin | Uncertain significance |