Run ID: ERR3797069
Sample name:
Date: 2024-04-15T13:51:30.574099
Number of reads: 256074
Percentage reads mapped: 25.43
Median coverage: 10.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| La1.2.BCG | M.bovis | None | 0.09 |
| lineage4 | Euro-American | None | 0.95 |
| lineage6.2.3 | West-Africa 2 | RD702 | 0.06 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.93 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.95 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| embB | 4247448 | p.His312Arg | missense_variant | 0.88 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 645 | c.645A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 649 | c.649C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 654 | c.654A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 660 | c.660G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 678 | c.678A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 681 | c.681G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 693 | c.693A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 720 | c.720G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 0.93 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 969 | c.969G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 975 | c.975G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 984 | c.984T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 993 | c.993A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 996 | c.996A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 999 | c.999C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1003 | c.1003C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1008 | c.1008G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1014 | c.1014C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1038 | c.1038A>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1041 | c.1041G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1047 | c.1047A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1098 | c.1098A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1110 | c.1110T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1113 | c.1113A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1125 | c.1125G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1254 | c.1254T>C | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6256 | c.1017G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6265 | c.1026C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6289 | c.1050C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6304 | c.-998C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 0.93 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6742 | c.-560A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6751 | c.-551G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6763 | c.1524G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6865 | c.-437G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642_1644delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6889 | c.-413G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6898 | c.-404G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6901 | c.-401G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6910 | c.-392G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6916 | c.-386G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7093 | c.-209T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7124 | c.1885_1887delTCGinsAC | frameshift_variant&missense_variant | 0.95 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7186 | c.1947C>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7216 | c.1977G>C | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7228 | c.-74C>T | upstream_gene_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7361 | c.60C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7562 | c.261C>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7625 | c.324G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7676 | c.375G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7823 | c.522G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8189 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8330 | c.1029C>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8337 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8342 | c.1041G>C | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8528 | c.1227G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8543 | c.1242C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8553 | c.1252C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8780 | p.Asp493Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8807 | c.1506C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8816 | c.1515C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8891 | c.1590G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8933 | c.1632G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9017 | c.1716C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9023 | c.1722A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9065 | c.1764C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9122 | c.1821C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9218 | c.1917C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9227 | c.1926C>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9293 | c.1992G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9299 | c.1998G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | c.2007C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9312 | c.2011C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9317 | c.2016G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9365 | c.2064G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9374 | c.2073G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| fgd1 | 490848 | c.66A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 490851 | c.69A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490868 | p.Ala29Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490887 | c.105G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490890 | c.108C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490935 | c.153C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490962 | c.180T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491077 | p.Asn99Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491130 | c.348C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491144 | p.Ala121Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491151 | c.369G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491643 | c.861G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491646 | c.864G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575649 | p.Val101Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575662 | c.315C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575665 | c.318G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575674 | c.327G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575701 | c.354G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575752 | c.405G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575755 | c.408G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575770 | c.423G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575809 | c.462C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575887 | c.540G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575950 | c.603C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575965 | c.618C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| ccsA | 619507 | c.-384A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619528 | c.-363C>G | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619531 | c.-360T>C | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619609 | c.-282G>T | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620265 | c.375C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620268 | c.378G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | c.394_396delGCGinsCC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620310 | c.420C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620346 | c.456C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620376 | c.486G>C | synonymous_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620389 | c.499C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620659 | c.769_771delCGCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620664 | c.774C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620682 | c.792G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620688 | c.798G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620710 | c.820_822delGTGinsAA | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620745 | c.855G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620763 | c.873G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620769 | c.879C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 656448 | c.1021_1023delATTinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656454 | c.1017G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656457 | c.1014T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656469 | c.1002T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656475 | c.996A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656484 | c.987T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731717 | c.-213T>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731732 | c.-198G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734370 | c.117A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734376 | c.123G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| nusG | 734556 | c.303C>T | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734559 | c.306T>C | synonymous_variant | 0.96 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734601 | c.348C>G | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734610 | c.357C>G | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734631 | c.378G>C | synonymous_variant | 0.93 | rifampicin | |
| nusG | 734634 | c.381G>C | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734637 | c.384G>C | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734643 | c.390G>C | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734652 | c.399T>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.92 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 0.92 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 760412 | c.606C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 0.95 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.91 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 760718 | c.912C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761006 | c.1200C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761129 | c.1323G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761213 | c.1407G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761219 | c.1413G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761306 | c.1500C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761312 | c.1506G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761477 | c.1671C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761588 | c.1782C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761815 | p.Ala670Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.91 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762206 | c.2400C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 762246 | c.2440C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.95 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762419 | c.-951C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762488 | c.2682G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 762521 | c.-849C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762810 | c.3004_3006delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762926 | c.3120C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763013 | c.-357C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763025 | c.-345C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763853 | p.Val162Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763936 | c.567C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763942 | c.573C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763948 | c.579G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763949 | c.580C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763954 | c.585C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763963 | c.594C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764236 | c.867G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764248 | c.879C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764353 | c.984G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764419 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764489 | c.1120C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 0.93 | rifampicin | Uncertain significance |
| rpoC | 765404 | p.Leu679Val | missense_variant | 0.89 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765580 | c.2211G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765613 | p.His748Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 0.89 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 0.89 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766030 | c.2661C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766096 | c.2727G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766462 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766660 | c.3291G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766673 | p.Gly1102Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766876 | c.3507C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766882 | c.3513C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.93 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpsL | 781700 | c.141G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781703 | c.144G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781772 | c.213C>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800794 | c.-15A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800796 | c.-13A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800817 | c.9A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800874 | c.66A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800875 | c.67_69delGTAinsAT | frameshift_variant&missense_variant | 1.0 | linezolid | |
| rplC | 800880 | c.72A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800892 | c.84G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800939 | p.Arg44Gln | missense_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800967 | c.159C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801300 | c.492C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801309 | c.501C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801321 | c.513C>T | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 1.0 | linezolid | |
| rplC | 801438 | c.630T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801442 | p.Ile212Val | missense_variant | 1.0 | linezolid | |
| fbiC | 1303497 | c.567G>A | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303501 | c.571C>T | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303521 | c.591C>T | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303530 | c.600G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303539 | c.609G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303728 | c.798G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303731 | c.801A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303761 | c.831T>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303785 | c.855G>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303797 | c.867A>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303836 | c.906G>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303845 | c.915C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303846 | p.Phe306Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303860 | c.930A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303914 | c.984C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303920 | c.990C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303998 | c.1068T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304031 | c.1101C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304034 | c.1104A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304046 | c.1116C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304049 | c.1119T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304050 | c.1120T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304058 | c.1128G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304059 | c.1129C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304067 | c.1137G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304085 | c.1155C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304097 | c.1167G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304106 | c.1176G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304127 | c.1197A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304132 | p.Ala401Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304142 | c.1212G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304661 | c.1731C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304711 | p.Ala594Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304739 | c.1809C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304832 | c.1902C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304862 | c.1932G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304875 | p.Ile649Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304883 | p.Glu651Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304891 | p.Ile654Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304907 | c.1977C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304983 | c.2053C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304995 | p.Leu689Met | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305030 | c.2100G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305033 | c.2103T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305173 | p.Asn748Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305177 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305181 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305186 | c.2256C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305210 | c.2280G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305215 | p.Ser762Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305231 | c.2301C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305234 | c.2304G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305240 | c.2310T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305243 | c.2313T>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305244 | c.2314T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305252 | c.2322G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305276 | c.2346G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305279 | p.His783Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305297 | c.2367G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305300 | c.2370A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305303 | c.2373T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305306 | c.2376A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305309 | c.2379G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305310 | p.Arg794Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305318 | c.2388C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305336 | c.2406T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305372 | c.2442G>A | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305384 | c.2454G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.95 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Not assoc w R | |||||
| rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673568 | c.-634C>G | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673580 | c.-622T>G | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673591 | c.-611C>T | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673596 | p.Lys53Glu | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673615 | p.Glu59Val | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674504 | c.303C>G | synonymous_variant | 0.82 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674507 | c.306G>C | synonymous_variant | 0.83 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674537 | c.336C>G | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674555 | c.354G>A | synonymous_variant | 0.93 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674561 | c.360C>T | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674601 | p.Leu134Thr | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674672 | c.471C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674708 | c.507G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674738 | c.537C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674741 | c.540C>T | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674753 | c.552G>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 0.92 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674759 | c.558G>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674774 | c.573A>G | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674789 | c.588G>C | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674816 | c.615T>C | synonymous_variant | 0.92 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674828 | c.627G>A | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674846 | p.Ile215Met | missense_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674864 | c.663C>T | synonymous_variant | 0.92 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674888 | c.687C>G | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833589 | c.48A>T | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833721 | c.180A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833886 | c.345C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834081 | c.540C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834096 | c.555G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834108 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834123 | c.582C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834210 | c.669C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834231 | c.690T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834618 | c.1077G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tlyA | 1917990 | c.51G>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1917993 | c.54A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| tlyA | 1917996 | c.57A>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918002 | c.63A>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918036 | p.Arg33Ser | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918048 | p.Leu37Met | missense_variant | 1.0 | capreomycin | |
| bacA | 2064933 | c.-205A>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064936 | c.-208C>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064942 | c.-214G>A | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064948 | c.-220G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064972 | c.-244T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064978 | c.-250G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064979 | c.-251C>T | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064984 | c.-256A>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064993 | c.-265T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| ndh | 2101894 | c.1149T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| katG | 2155661 | p.Val151Ile | missense_variant | 0.91 | isoniazid | |
| katG | 2155680 | c.432G>C | synonymous_variant | 0.91 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 0.91 | isoniazid | |
| katG | 2155695 | c.417C>G | synonymous_variant | 0.91 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 0.92 | isoniazid | |
| katG | 2155716 | c.396T>G | synonymous_variant | 0.92 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 0.92 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 0.92 | isoniazid | |
| katG | 2155740 | p.Gly124Gln | missense_variant | 0.92 | isoniazid | |
| katG | 2155743 | c.369G>C | synonymous_variant | 0.92 | isoniazid | |
| katG | 2155782 | c.330C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155785 | c.327T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518639 | c.525G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518657 | c.543G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518693 | c.579C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518696 | c.582C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518702 | c.588C>T | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518705 | c.591T>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518744 | c.630C>T | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518768 | c.654C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518777 | c.663C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518879 | c.765A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518910 | p.Leu266Met | missense_variant | 1.0 | isoniazid | |
| kasA | 2518921 | c.807T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518927 | c.813C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518936 | c.822C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518939 | c.825T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518942 | c.828T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518951 | c.837G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518954 | c.840C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518963 | c.849T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518969 | c.855T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518975 | c.861C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518979 | c.865A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518990 | c.876T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518993 | c.879C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518999 | c.885G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519008 | c.894C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519017 | c.903G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519020 | c.906G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519021 | p.Ala303Lys | missense_variant | 1.0 | isoniazid | |
| kasA | 2519027 | c.913_915delATCinsGT | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519050 | c.936C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519053 | c.939G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519062 | c.948T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519068 | c.954C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519072 | p.Ala320Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2519107 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519108 | c.994_996delGATinsCG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519116 | c.1002C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519122 | c.1008G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519158 | c.1044C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| folC | 2746468 | c.1131G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746478 | p.Phe374Tyr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746480 | c.1119A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746492 | c.1107G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746495 | p.His368Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746507 | c.1092A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746510 | c.1089A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746516 | c.1083T>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746519 | p.Ser360Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746525 | c.1074G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746531 | c.1068G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746564 | c.1035A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746576 | c.1023C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783044 | c.999G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.951A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783095 | c.948C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783101 | c.942G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783140 | c.903C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783146 | c.897G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783149 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783179 | c.864G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783182 | c.861C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783185 | c.858G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783209 | c.834G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783221 | c.822G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783224 | c.819C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783230 | c.813T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783235 | c.808T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783275 | c.768C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783293 | c.750G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783359 | c.684G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783485 | c.558G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783497 | c.544_546delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783521 | c.522G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783539 | c.504G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783554 | c.489C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783839 | c.204C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783863 | c.180C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783887 | c.156C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783929 | c.114C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783932 | c.111C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783953 | c.90G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065151 | c.1041G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065183 | p.Ser337Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065196 | c.996T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065202 | c.990T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065205 | c.987T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065210 | c.982T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065223 | c.969T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065229 | c.963G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065232 | c.960T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065451 | c.741G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065457 | c.735A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065463 | c.729T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065481 | c.711T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065487 | c.705T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065490 | c.702A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065493 | c.699G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065499 | c.693A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065502 | p.Asp230Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065508 | c.684T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065511 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065517 | c.675C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065523 | c.669C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066102 | c.90C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066522 | c.-331C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066855 | c.-664T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066859 | c.-668C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066864 | c.-673C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066867 | c.-676T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066876 | c.-685T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066879 | c.-688T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067274 | c.672C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067277 | c.669C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067281 | p.Val222Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067284 | p.Ala221Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067286 | c.660C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067289 | c.657C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067292 | c.654G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067295 | c.651C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067325 | c.621A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067349 | c.597G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067367 | c.579G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067376 | c.570G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067445 | c.501C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067465 | p.Ile161Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067475 | c.471A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067490 | c.456C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067493 | c.453A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067530 | p.Ala139Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067545 | p.Glu134Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067549 | p.Thr133Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067556 | p.His130Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067559 | c.387C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067565 | p.Asp127Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067570 | p.Ala126Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067577 | c.369G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067583 | c.363C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067601 | p.Arg115His | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067611 | p.Lys112Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067619 | c.327A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067631 | c.315C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067634 | c.312C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067685 | c.261A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067691 | c.253_255delATCinsCG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067736 | c.208_210delTTCinsCT | frameshift_variant&missense_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067739 | c.207T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067761 | p.Arg62Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067772 | c.174C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067799 | c.147G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073836 | c.636C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073839 | c.633T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073860 | c.612C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073866 | c.606C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073872 | c.598_600delATCinsGG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073892 | c.580T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073898 | p.Ala192Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073917 | c.555C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074079 | c.393G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074097 | c.375C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074100 | c.370_372delGATinsAC | frameshift_variant&synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074127 | c.345G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074130 | c.342G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074154 | c.318T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074157 | c.315C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074160 | c.312A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074163 | c.307_309delGCTinsAG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074172 | c.300G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074175 | c.297A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074181 | c.291A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074187 | c.285T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074205 | p.Glu89Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074214 | c.258T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| lpqB | 3623492 | c.1419T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623512 | p.Gly467Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623612 | p.Thr433Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623630 | c.1281G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624041 | p.Glu290Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624050 | c.861C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624077 | c.834G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624082 | c.829A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624086 | c.825C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624092 | c.817_819delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624100 | c.811T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624101 | c.810C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624107 | c.804C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624116 | c.795A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624119 | c.792C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624124 | p.Leu263Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624125 | c.786A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624143 | c.768T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624166 | p.Met249Leu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624167 | c.744C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624173 | c.738A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624179 | c.732C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624185 | c.726C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624194 | c.717C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624200 | c.711A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624204 | p.Ser236Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624209 | c.702A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624673 | p.Ala80Ser | missense_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624674 | c.237C>T | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624680 | c.231T>A | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624686 | c.223_225delGAAinsCG | frameshift_variant&missense_variant | 0.9 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624701 | c.210T>C | synonymous_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624707 | c.204G>C | synonymous_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624722 | c.189C>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625087 | c.1525_1527delGCCinsTG | frameshift_variant&missense_variant | 0.8 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625093 | p.Glu507Asp | missense_variant | 0.8 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625099 | c.-189C>G | upstream_gene_variant | 0.83 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.87 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.87 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 0.88 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625135 | c.1479A>G | synonymous_variant | 0.88 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 0.88 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 0.88 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625149 | p.Val489Ile | missense_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.94 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625165 | c.-255G>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625206 | p.Ser470Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.91 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625572 | p.Thr348Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625616 | p.Arg333Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625636 | c.978C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625705 | c.909C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625750 | c.864G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625797 | p.Val273Met | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625807 | c.807C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625876 | c.738G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | c.411A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627071 | c.279G>T | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627188 | c.162A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627221 | c.129C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiB | 3642620 | c.1086T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642656 | c.1122G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642662 | c.1128C>G | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642668 | c.1134A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642684 | c.1150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642701 | c.1167C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rpoA | 3877507 | p.Gly334Ala | missense_variant | 0.85 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 0.86 | rifampicin | |
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.94 | rifampicin | |
| rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.94 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 0.95 | rifampicin | |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877679 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877791 | c.717C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.88 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.86 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 0.9 | rifampicin | |
| rpoA | 3877878 | c.630G>C | synonymous_variant | 0.89 | rifampicin | |
| rpoA | 3877890 | c.618C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 0.89 | rifampicin | |
| rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.89 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.95 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878043 | c.465G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878076 | c.432C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878082 | c.426T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878141 | p.Met123Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878172 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878181 | c.327C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878199 | c.309T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878226 | c.282C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878232 | c.276G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878284 | p.Glu75Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878860 | c.-353C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4035698 | c.2504_*2459del | frameshift_variant&stop_lost&splice_region_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038407 | c.2298G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038489 | p.Ala739Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038497 | p.Ser736Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038821 | c.1884G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038845 | c.1860G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039186 | c.1519C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039229 | c.1476C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039364 | c.1341C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039480 | c.1225C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039570 | p.Met379Leu | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039576 | p.Ala377Pro | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039625 | c.1080G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039988 | c.717C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040231 | c.474C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040318 | c.387C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040501 | c.204C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040537 | c.168G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044737 | c.-456T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044746 | c.-467_-465delGTGinsAC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044752 | c.-471T>C | upstream_gene_variant | 0.91 | pyrazinamide | |
| panD | 4044758 | c.-477C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045000 | c.-719A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045001 | c.-720G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045019 | c.-738G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045022 | c.-741C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045028 | c.-747C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045034 | c.-753A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045055 | c.-774T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045067 | c.-786C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 0.9 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138695 | p.Pro354Asp | missense_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138721 | c.1035G>A | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138730 | c.1026C>G | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138763 | c.993G>A | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138769 | c.987G>C | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139561 | c.195G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139581 | p.Asn59Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4139588 | c.168G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240685 | p.Thr275Ala | missense_variant | 0.9 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| embC | 4240789 | c.927T>C | synonymous_variant | 0.91 | ethambutol | |
| embC | 4241032 | c.1170G>C | synonymous_variant | 0.8 | ethambutol | |
| embC | 4241038 | c.1176G>C | synonymous_variant | 0.82 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 0.83 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 0.92 | ethambutol | |
| embC | 4241053 | c.1191G>C | synonymous_variant | 0.83 | ethambutol | |
| embC | 4241089 | c.1227C>G | synonymous_variant | 0.9 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 0.95 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 0.95 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241146 | c.1284C>G | synonymous_variant | 0.94 | ethambutol | |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241170 | c.1308G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241173 | c.1311C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241206 | c.1344G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241453 | p.Ile531Val | missense_variant | 0.9 | ethambutol | |
| embC | 4241479 | c.1617C>G | synonymous_variant | 0.93 | ethambutol | |
| embC | 4241480 | c.1618T>C | synonymous_variant | 0.93 | ethambutol | |
| embC | 4241488 | c.1626G>C | synonymous_variant | 0.93 | ethambutol | |
| embC | 4241496 | p.Ala545Gly | missense_variant | 0.92 | ethambutol | |
| embC | 4241500 | c.1638A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241501 | p.Ser547Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4241506 | c.1644G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241530 | c.1668C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241545 | c.1683T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241548 | c.1686T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241551 | c.1689A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241567 | p.Ile569Val | missense_variant | 1.0 | ethambutol | |
| embA | 4242748 | c.-485A>G | upstream_gene_variant | 0.82 | ethambutol | |
| embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.85 | ethambutol | |
| embC | 4242764 | p.Val968Leu | missense_variant | 0.87 | ethambutol | |
| embC | 4242779 | p.Asn973Asp | missense_variant | 0.86 | ethambutol | |
| embC | 4242791 | c.2929_2931delGCAinsTC | frameshift_variant&missense_variant | 0.87 | ethambutol | |
| embA | 4242796 | c.-437G>C | upstream_gene_variant | 0.87 | ethambutol | |
| embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.87 | ethambutol | |
| embA | 4242820 | c.-413G>C | upstream_gene_variant | 0.88 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.89 | ethambutol | |
| embA | 4242832 | c.-401A>C | upstream_gene_variant | 0.88 | ethambutol | |
| embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.93 | ethambutol | |
| embC | 4242841 | c.2979C>T | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.93 | ethambutol | |
| embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.93 | ethambutol | |
| embA | 4242859 | c.-374C>T | upstream_gene_variant | 0.87 | ethambutol | |
| embA | 4242862 | c.-371A>G | upstream_gene_variant | 0.86 | ethambutol | |
| embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.86 | ethambutol | |
| embA | 4244611 | p.Ala460Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245146 | c.1914G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245153 | p.Ile641Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245189 | c.1957C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4246103 | c.2871C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246109 | c.-405C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4247386 | c.873T>C | synonymous_variant | 0.82 | ethambutol | |
| embB | 4247389 | c.876C>G | synonymous_variant | 0.83 | ethambutol | |
| embB | 4247395 | c.882C>G | synonymous_variant | 0.85 | ethambutol | |
| embB | 4247401 | c.888T>C | synonymous_variant | 0.86 | ethambutol | |
| embB | 4247407 | c.894G>C | synonymous_variant | 0.86 | ethambutol | |
| embB | 4247413 | c.900C>T | synonymous_variant | 0.87 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 0.88 | ethambutol | Not assoc w R - Interim |
| embB | 4247440 | c.927C>G | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247446 | c.933C>T | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 0.94 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 0.89 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 0.9 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 0.9 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 0.89 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 0.92 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 0.91 | ethambutol | |
| embB | 4247566 | c.1053C>A | synonymous_variant | 0.9 | ethambutol | |
| embB | 4247776 | c.1263G>T | synonymous_variant | 0.91 | ethambutol | |
| embB | 4247797 | c.1284C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247800 | c.1287A>T | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247803 | c.1290G>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247815 | c.1302C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247819 | c.1306_1308delGTTinsAC | frameshift_variant&missense_variant | 0.92 | ethambutol | |
| embB | 4247830 | c.1317A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247836 | c.1323A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247839 | c.1326G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247866 | c.1353G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247875 | c.1362G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247876 | c.1363C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247881 | c.1368G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247887 | c.1374C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247893 | c.1380C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247899 | p.Met462Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247905 | c.1392G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247909 | c.1396T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247932 | c.1419C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247940 | p.Leu476Trp | missense_variant | 1.0 | ethambutol | |
| embB | 4247945 | c.1432T>C | synonymous_variant | 0.94 | ethambutol | |
| embB | 4247951 | p.Ser480Ala | missense_variant | 0.94 | ethambutol | |
| embB | 4247956 | c.1443G>C | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embB | 4247974 | c.1461C>G | synonymous_variant | 0.94 | ethambutol | |
| embB | 4248007 | c.1494C>G | synonymous_variant | 0.94 | ethambutol | |
| embB | 4248035 | p.Val508Ile | missense_variant | 0.94 | ethambutol | |
| embB | 4248040 | c.1527C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 0.93 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 0.93 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248139 | c.1626C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248205 | c.1692C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248304 | c.1791G>C | synonymous_variant | 0.94 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248343 | c.1830G>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248355 | c.1842A>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248358 | c.1845C>G | synonymous_variant | 0.92 | ethambutol | |
| embB | 4248361 | c.1848A>C | synonymous_variant | 0.92 | ethambutol | |
| embB | 4248362 | p.Ser617Ala | missense_variant | 0.92 | ethambutol | |
| embB | 4248373 | c.1860C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248386 | c.1873C>A | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248407 | p.Leu632Val | missense_variant | 0.95 | ethambutol | |
| embB | 4248410 | c.1897_1899delTTCinsCG | frameshift_variant&missense_variant | 0.95 | ethambutol | |
| embB | 4248419 | p.Leu636Met | missense_variant | 0.95 | ethambutol | |
| embB | 4248425 | c.1912T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248430 | c.1917T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248432 | p.Trp640Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4248457 | c.1944T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248472 | c.1959T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248475 | c.1962G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248488 | c.1975_1977delGCGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248500 | p.Ile663Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248504 | p.Asp664Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248508 | c.1995G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248512 | c.1999_2001delACAinsTG | frameshift_variant&stop_gained | 1.0 | ethambutol |
