TB-Profiler result

Run: SRR1175507
Summary

Run ID: SRR1175507

Sample name:

Date: 2024-03-26T14:25:47.850192

Number of reads: 351501

Percentage reads mapped: 8.61

Median coverage: 5.0

Strain: lineage4.1.1.3;lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1 Euro-American None 0.31
lineage4.1.1.3 Euro-American (X-type) RD193 0.13
lineage4 Euro-American None 1.0
lineage4.1.1 Euro-American (X-type) None 0.11
lineage4.9 Euro-American (H37Rv-like) None 0.65
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 693 c.693A>C synonymous_variant 0.6 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.61 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.61 isoniazid
dnaA 714 c.714C>T synonymous_variant 0.61 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.65 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>T synonymous_variant 0.59 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.59 isoniazid Uncertain significance
dnaA 763 p.Lys255Arg missense_variant 0.59 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.7 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.69 isoniazid Uncertain significance
dnaA 801 c.801G>T synonymous_variant 0.7 isoniazid
dnaA 804 c.804G>C synonymous_variant 0.7 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.7 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 0.79 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.78 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.76 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.79 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.76 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 885 c.885T>C synonymous_variant 0.75 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.75 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.73 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.63 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.55 isoniazid
gyrB 6136 c.897G>A synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6193 c.954G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6203 p.Ser322Ala missense_variant 0.47 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6229 c.990G>A synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.52 levofloxacin Uncertain significance
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6754 c.-548C>T upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.35 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6808 c.1569C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>A upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrB 6872 c.1633_1635delTTGinsCT frameshift_variant&synonymous_variant 0.41 levofloxacin Uncertain significance
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>A upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.56 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>T upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7403 c.102C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7511 c.210C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7589 c.288G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8121 c.820T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8159 c.858G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8187 c.886_888delCTGinsAT frameshift_variant&missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8192 c.891C>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCA frameshift_variant&missense_variant 0.52 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8327 c.1026C>T synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8330 c.1029C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.71 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8580 p.Ile427Val missense_variant 0.57 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8603 c.1302A>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8957 c.1656C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Lys missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 8978 c.1677C>T synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8993 c.1692C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.46 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9018 p.Gln573Lys missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin
hadA 731738 c.-192G>C upstream_gene_variant 0.56 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.72 isoniazid
hadA 731753 c.-177A>T upstream_gene_variant 0.69 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.72 isoniazid
hadA 731760 c.-170_-169delGTinsAC upstream_gene_variant 0.61 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.64 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.52 isoniazid
hadA 731810 c.-120G>A upstream_gene_variant 0.57 isoniazid
hadA 731813 c.-117C>T upstream_gene_variant 0.47 isoniazid
nusG 734472 c.219T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734497 c.244_246delGTGinsAC frameshift_variant&missense_variant 0.74 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
nusG 734535 c.282C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760079 c.273G>A synonymous_variant 0.5 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760110 c.304_306delTCTinsAGC synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760118 c.312T>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.61 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.55 rifampicin Uncertain significance
rpoB 760276 p.Lys157Met missense_variant 0.53 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760588 p.Thr261Ile missense_variant 0.65 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.68 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.65 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.65 rifampicin
rpoB 760608 c.802C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760668 c.862_864delACGinsGC frameshift_variant&missense_variant 0.71 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760826 c.1020C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.89 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760865 c.1059C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760886 p.Glu360Asp missense_variant 0.87 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.87 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760928 c.1122G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760943 c.1137C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.58 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761657 c.1851C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.94 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.93 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.83 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.8 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.64 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.57 rifampicin
rpoB 761847 p.Cys681Lys missense_variant 0.54 rifampicin
rpoB 761863 p.Ala686Glu missense_variant 0.54 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 0.54 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 0.54 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.54 rifampicin
rpoB 761880 p.Ala692Thr missense_variant 0.61 rifampicin Uncertain significance
rpoB 761891 c.2085G>C synonymous_variant 0.7 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.65 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.68 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.68 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.7 rifampicin
rpoB 761924 c.2118G>A synonymous_variant 0.74 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.64 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 0.68 rifampicin
rpoB 761936 c.2130C>T synonymous_variant 0.68 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>A synonymous_variant 0.74 rifampicin
rpoB 761955 p.Ile717Val missense_variant 0.77 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.88 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.81 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.89 rifampicin
rpoB 762134 c.2328C>A synonymous_variant 0.77 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.79 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.84 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762515 c.2709C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.63 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.63 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.63 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.6 rifampicin
rpoC 762830 c.-540C>T upstream_gene_variant 0.75 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762866 c.3060C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.86 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 763145 c.3339G>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763193 c.3387C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.8 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.92 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.92 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.85 rifampicin
rpoC 763732 c.363C>A synonymous_variant 0.91 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.92 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.92 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.67 rifampicin
rpoC 764054 c.685C>T synonymous_variant 0.79 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.81 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.76 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.76 rifampicin
rpoC 764095 c.726C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764098 c.729A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764311 c.942C>G synonymous_variant 0.7 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.7 rifampicin
rpoC 764332 c.963G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.93 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764534 c.1165C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.84 rifampicin Not assoc w R
rpoC 764810 p.Pro481Ala missense_variant 0.85 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.84 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.82 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579_1581delTTGinsCC frameshift_variant&missense_variant 0.76 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.5 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765449 c.2080_2082delGCCinsTG frameshift_variant&missense_variant 0.89 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765469 c.2100G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>G synonymous_variant 0.82 rifampicin
rpoC 765480 p.Tyr704Phe missense_variant 0.82 rifampicin Uncertain significance
rpoC 765499 c.2130C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765533 p.Tyr722His missense_variant 0.72 rifampicin Uncertain significance
rpoC 765544 c.2175C>G synonymous_variant 0.69 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.65 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.69 rifampicin
rpoC 765562 c.2193G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765841 c.2472G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765861 p.Phe831Tyr missense_variant 0.81 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.91 rifampicin Uncertain significance
rpoC 765907 c.2538G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.82 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 0.79 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.82 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.83 rifampicin
rpoC 766507 c.3138C>T synonymous_variant 0.83 rifampicin
rpoC 766513 c.3144C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>A synonymous_variant 0.86 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.86 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.86 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.86 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.86 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.88 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.92 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 0.93 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766588 c.3219G>A synonymous_variant 0.96 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.96 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.94 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.93 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.92 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.92 rifampicin
rpoC 766633 c.3264G>C synonymous_variant 0.92 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767107 c.3738C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767179 c.3810C>T synonymous_variant 0.94 rifampicin
rpoC 767180 p.Ala1271Ser missense_variant 0.93 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.81 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.85 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767264 c.3895_3897delGCGinsTC frameshift_variant&missense_variant 0.88 rifampicin
rpoC 767267 p.Ala1300Asn missense_variant 0.84 rifampicin Uncertain significance
rpoC 767281 c.3912C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpsL 781616 c.57C>G synonymous_variant 0.8 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.84 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.83 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.8 streptomycin
rpsL 781658 c.99A>C synonymous_variant 0.8 streptomycin Not assoc w R - Interim
rpsL 781670 c.111G>C synonymous_variant 0.76 streptomycin
rpsL 781706 c.147T>C synonymous_variant 0.47 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.33 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.37 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.37 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.44 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.7 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.76 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.8 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.83 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.82 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.81 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.83 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.86 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.8 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.81 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.77 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.7 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.66 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.59 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.58 streptomycin
rplC 800672 c.-137G>C upstream_gene_variant 0.65 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.74 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.78 linezolid
rplC 800703 c.-106_-104delTTGinsCC upstream_gene_variant 0.86 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.92 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.94 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.94 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.94 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.86 linezolid
rplC 800780 c.-29C>G upstream_gene_variant 0.79 linezolid
atpE 1461101 c.57T>A synonymous_variant 0.62 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.81 bedaquiline
atpE 1461146 c.102G>T synonymous_variant 0.8 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.82 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.7 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.73 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.68 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.72 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.68 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.68 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472043 n.198T>A non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472050 n.205G>C non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.47 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473684 n.27G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1473707 n.50T>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473839 n.182G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1473950 n.293G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474074 n.417C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474103 n.446A>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474106 n.449_450insCT non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474109 n.453_454delAT non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756A>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474415 n.759_781delCACACGCGCATACGCGCGTGTGA non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1052_1060delGTGGTGTAAinsAATAAGTTAG non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1406delA non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1475220 n.1563G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475766 n.2109G>T non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476114 n.2457T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.22 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.21 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.21 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.27 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.89 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476684 n.3027C>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
inhA 1674903 c.702T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.8 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674949 c.748C>T synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 0.64 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 0.56 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.89 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.88 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.88 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833616 c.75A>T synonymous_variant 0.85 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.82 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.8 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.76 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.76 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.73 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.75 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.67 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.72 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 0.73 pyrazinamide
rpsA 1833700 c.159C>T synonymous_variant 0.74 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.82 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.78 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.86 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 0.79 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.83 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.86 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.89 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.89 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.89 pyrazinamide
rpsA 1833823 c.282G>A synonymous_variant 0.85 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.88 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.79 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.78 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.75 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.72 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.83 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.82 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.87 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.86 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.88 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.85 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.84 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 0.82 pyrazinamide
rpsA 1834073 p.Lys178Arg missense_variant 0.83 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.77 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834228 c.687C>A synonymous_variant 0.5 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.52 pyrazinamide
rpsA 1834234 c.693G>T synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.57 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.59 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>T synonymous_variant 0.78 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.76 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.78 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.89 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.72 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.69 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834420 c.879C>T synonymous_variant 0.7 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834438 c.897C>T synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.68 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.62 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834520 c.979_981delGCCinsTG frameshift_variant&missense_variant 0.68 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834534 c.993C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.69 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.67 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.7 pyrazinamide
rpsA 1834557 p.Ala339Gly missense_variant 0.7 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.81 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.87 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834645 c.1104C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.88 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834700 p.Gln387Ala missense_variant 0.88 pyrazinamide
rpsA 1834705 c.1164C>G synonymous_variant 0.88 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.87 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.78 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.75 pyrazinamide
ndh 2102857 c.186T>C synonymous_variant 0.53 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 0.53 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102875 c.168C>T synonymous_variant 0.47 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
kasA 2517917 c.-198G>C upstream_gene_variant 0.98 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.94 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.93 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.93 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.91 isoniazid
kasA 2517968 c.-147T>A upstream_gene_variant 0.86 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.84 isoniazid
Rv2477c 2783344 c.699C>T synonymous_variant 0.73 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
mtrB 3625705 c.909C>G synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625708 c.906C>T synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625744 c.870G>A synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.87 bedaquiline
rifampicin Uncertain significance
mtrB 3625761 p.Gln285Glu missense_variant 0.82 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>T synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626669 c.-56T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3626681 c.-68C>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626717 c.-104C>T upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626756 c.594C>G synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626759 c.591T>C synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626762 c.588G>C synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626786 c.564A>G synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626804 c.546A>G synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627073 c.277C>T synonymous_variant 0.5 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>T upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>G upstream_gene_variant 0.6 bedaquiline
rifampicin
rpoA 3877542 c.966C>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877545 c.963G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877554 c.954G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877563 c.945C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsAC frameshift_variant&missense_variant 0.64 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877614 c.894G>A synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877620 c.888G>A synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877677 c.831G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3877797 c.711G>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877815 c.693C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>A synonymous_variant 0.89 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 0.85 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.89 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877977 p.Lys177Asn missense_variant 0.87 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878091 c.417C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878102 p.Val136Ile missense_variant 0.85 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.85 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.92 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.83 rifampicin
rpoA 3878142 p.Gly122Asp missense_variant 0.82 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.78 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.89 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878343 c.165C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.84 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.91 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.86 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.86 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.86 rifampicin
rpoA 3878381 c.127C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878391 c.117T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878400 c.108T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3879058 c.-551C>T upstream_gene_variant 0.57 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.6 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.65 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 0.68 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.7 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.72 rifampicin
rpoA 3879097 c.-590C>T upstream_gene_variant 0.72 rifampicin
rpoA 3879121 c.-615_-614delTTinsAG upstream_gene_variant 0.81 rifampicin
rpoA 3879124 c.-618_-617delTGinsGC upstream_gene_variant 0.72 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.76 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.79 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.65 rifampicin
clpC1 4038545 c.2158_2160delCACinsGG frameshift_variant&missense_variant 0.79 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038584 c.2121G>T synonymous_variant 0.75 pyrazinamide
clpC1 4038587 c.2118C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.75 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.73 pyrazinamide
clpC1 4038737 c.1968C>T synonymous_variant 0.57 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.67 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.64 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.61 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.58 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.75 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.82 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.84 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.77 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.77 pyrazinamide
clpC1 4038857 c.1848C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.77 pyrazinamide
clpC1 4038911 c.1794G>C synonymous_variant 0.72 pyrazinamide
clpC1 4038914 c.1791G>T synonymous_variant 0.69 pyrazinamide
clpC1 4038923 c.1782A>T synonymous_variant 0.76 pyrazinamide
clpC1 4038928 c.1777C>A synonymous_variant 0.82 pyrazinamide
clpC1 4038929 c.1776G>A synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4038932 c.1773G>C synonymous_variant 0.79 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.81 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.76 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.62 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.56 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.59 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.92 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.76 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.78 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.77 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4039430 c.1275T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4039466 c.1239T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039528 c.1177C>A synonymous_variant 0.94 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.93 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039619 c.1086G>A synonymous_variant 0.8 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.75 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.67 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.68 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.64 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039964 c.741C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039975 p.Asp244Asn missense_variant 0.74 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4040009 c.696C>G synonymous_variant 0.77 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 0.78 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.96 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040174 c.531C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.67 pyrazinamide
clpC1 4040309 c.396C>T synonymous_variant 0.68 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040342 c.363C>A synonymous_variant 0.78 pyrazinamide
clpC1 4040348 c.357G>T synonymous_variant 0.76 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.68 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.62 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.57 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.62 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.71 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.71 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>T synonymous_variant 0.79 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.89 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040558 c.147G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.94 pyrazinamide
panD 4044150 c.132A>C synonymous_variant 0.93 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
panD 4044167 c.115C>T synonymous_variant 1.0 pyrazinamide
panD 4044171 c.111C>T synonymous_variant 1.0 pyrazinamide
panD 4044174 c.108C>T synonymous_variant 1.0 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 1.0 pyrazinamide
panD 4044186 c.94_96delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
panD 4044189 c.93C>T synonymous_variant 1.0 pyrazinamide
panD 4044194 p.Ala30Pro missense_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
glpK 4138601 c.1155G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4240819 c.957A>C synonymous_variant 0.8 ethambutol