Run ID: SRR6045233
Sample name:
Date: 2024-04-15T08:12:27.174574
Number of reads: 290577
Percentage reads mapped: 26.5
Median coverage: 7.0
Strain: M.canetti;lineage4.9
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 0.91 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.94 |
M.canetti | M.canetti | None | 0.06 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.166_168delTCCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
fbiC | c.1963_1965delGGCinsAT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 490948 | c.166_168delTCCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304893 | c.1963_1965delGGCinsAT | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 741 | c.741T>C | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
dnaA | 756 | c.756T>C | synonymous_variant | 0.92 | isoniazid | |
dnaA | 771 | c.771A>G | synonymous_variant | 0.93 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.94 | isoniazid | |
dnaA | 810 | c.810C>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.95 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.95 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.95 | isoniazid | Not assoc w R - Interim |
dnaA | 876 | c.876C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 894 | c.894G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 930 | c.930G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 975 | c.975G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1350 | c.1350G>A | synonymous_variant | 0.92 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1362 | c.1362C>G | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
dnaA | 1369 | c.1369_1371delCTTinsTG | frameshift_variant&missense_variant | 0.93 | isoniazid | Uncertain significance |
dnaA | 1375 | c.1375T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1434 | c.1434C>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1441 | c.1441C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1467 | c.1467G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
gyrB | 5254 | c.15A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5261 | c.22_24delGCCinsCT | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5269 | p.Asp10Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5271 | p.Glu11Gly | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5282 | c.43_45delGCGinsTA | frameshift_variant&stop_gained | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5287 | c.48T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5294 | c.55_57delATTinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 5317 | c.78C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5326 | c.87T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5329 | c.90C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5332 | c.93C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 5338 | c.99C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5341 | c.102T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5347 | c.108G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5362 | c.123T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5371 | c.132T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6184 | c.945C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6259 | p.Asp340Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6266 | p.Pro343Ala | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6316 | c.-986G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6346 | c.-956C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6385 | c.-917G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6766 | c.-536G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6772 | c.1533C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6794 | p.Ile519Leu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6797 | p.Gly520Ser | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6808 | c.1569C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6869 | c.-433T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6889 | c.-413G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6898 | c.-404G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6904 | c.-398C>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6926 | c.1687T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6937 | c.-365G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6950 | c.1711_1713delCTCinsTG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6970 | c.-332C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7018 | c.-284G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7069 | c.-233C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7096 | c.-206G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7100 | c.1861T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7114 | c.-188C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7123 | c.-179C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7150 | c.-152G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7162 | c.-140C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7189 | c.-113C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7190 | c.-112C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7412 | c.111C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7421 | c.120G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7526 | c.225G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7587 | c.286C>T | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7619 | c.318C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7622 | c.321C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7628 | c.327G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7667 | c.366C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382_384delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7821 | c.520C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7838 | c.537C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8354 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8360 | c.1059G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8438 | c.1137C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8537 | c.1236G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8555 | c.1254G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8618 | c.1317G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8633 | c.1332C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8717 | c.1416C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8723 | c.1422G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Thr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8783 | c.1482G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8796 | p.Ile499Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528_1530delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8906 | c.1605C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9164 | c.1863G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9174 | c.1873C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9179 | c.1878C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9263 | c.1962C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9268 | p.Asn656Ser | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9338 | c.2037G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9629 | c.2328C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9650 | c.2349G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9659 | c.2358C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9665 | c.2364A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9674 | c.2373T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490929 | c.147C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490938 | c.156G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491280 | c.498C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491289 | c.507C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491307 | c.525C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491310 | c.528C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491340 | c.558C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575593 | c.246G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575803 | c.456C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575806 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575887 | c.540G>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575899 | c.552G>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575908 | c.561A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575920 | c.573C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619576 | c.-315C>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619588 | c.-303C>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619627 | c.-264C>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620319 | c.429C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620343 | c.453G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620583 | c.693G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620622 | c.732G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620659 | c.769_771delCGCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620724 | c.834C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620758 | c.868_870delCGCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620766 | c.876C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620769 | c.879C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620783 | p.Ala298Val | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620793 | c.903G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656511 | p.His320Arg | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656540 | p.Ser311Gly | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656542 | p.Thr310Ser | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656546 | p.Ile309Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656556 | c.915G>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656945 | c.526C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656952 | c.519A>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656973 | c.498A>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656976 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656982 | p.Gly163Ala | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656985 | c.486T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656988 | p.Lys161Arg | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656991 | p.Glu160Asp | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657000 | p.Gly157Pro | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657015 | c.456C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657027 | c.444T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657231 | c.238_240delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657242 | p.Glu77Lys | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657297 | c.174G>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657303 | c.168C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657337 | p.Arg45Gln | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657639 | c.-169C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657644 | c.-174G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657686 | c.-216C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657732 | c.-263_-262delAGinsGA | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
hadA | 731682 | c.-248C>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731687 | c.-243G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731688 | c.-242C>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731689 | c.-241A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731690 | c.-240A>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731694 | c.-235_-234delCG | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731698 | c.-232_-231insCCTAGAGAGC | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731711 | c.-219T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731753 | c.-177A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731756 | c.-174C>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731933 | p.Ala2Ser | missense_variant | 1.0 | isoniazid | |
hadA | 731944 | c.15A>G | synonymous_variant | 1.0 | isoniazid | |
hadA | 731945 | c.16_18delGACinsAT | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
hadA | 731953 | c.24T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 731962 | c.33T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 731968 | c.39G>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 731977 | c.48C>T | synonymous_variant | 1.0 | isoniazid | |
hadA | 731980 | c.51C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
hadA | 732238 | c.309G>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732252 | p.Tyr108Trp | missense_variant | 1.0 | isoniazid | |
hadA | 732259 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732268 | c.339T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
hadA | 732272 | p.Ala115Ser | missense_variant | 1.0 | isoniazid | |
hadA | 732298 | c.369C>G | synonymous_variant | 1.0 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
hadA | 732314 | p.Asn129Asp | missense_variant | 1.0 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
hadA | 732329 | c.400_402delCTCinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732370 | c.441C>T | synonymous_variant | 1.0 | isoniazid | |
hadA | 732391 | c.462T>A | synonymous_variant | 1.0 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734139 | c.-115C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734150 | c.-104G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734173 | c.-81C>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734175 | c.-79_-77delGGTinsCTG | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734180 | c.-74T>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734186 | c.-68G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734193 | c.-61A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734201 | c.-53G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734205 | c.-49A>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734208 | c.-46T>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734224 | c.-30G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734226 | c.-28T>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734227 | c.-27C>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734232 | c.-22G>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734415 | c.162C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734421 | c.168A>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734472 | c.219T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.9 | rifampicin | |
rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760106 | c.300G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760124 | c.318C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760172 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760313 | c.507G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760971 | c.1165C>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761171 | c.1365C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761300 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761301 | c.1495C>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761457 | p.Pro551Gly | missense_variant | 1.0 | rifampicin | |
rpoB | 761465 | c.1659G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761504 | c.1698C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761600 | c.1794T>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761693 | c.1887G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761720 | c.1914C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsG | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 1.0 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
rpoB | 761951 | c.2145G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761969 | c.2163G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762161 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.89 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 762389 | c.-981G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762446 | c.-924C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762485 | c.2679G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762486 | p.Pro894Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 762503 | c.-867G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762590 | c.-780C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762596 | c.-774G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762599 | c.2793T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762605 | c.-765T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762608 | c.-762C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762630 | p.Ala942Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762634 | p.Ala943Gly | missense_variant | 1.0 | rifampicin | |
rpoC | 762644 | c.-726T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762728 | c.-642C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762795 | p.Asp997Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762868 | p.Tyr1021Phe | missense_variant | 1.0 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763184 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763409 | c.40_42delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763492 | c.123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763648 | c.279C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763672 | c.303C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763729 | c.360G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763768 | c.399C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763791 | p.Glu141Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
rpoC | 763851 | p.Ala161Gly | missense_variant | 1.0 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 763876 | c.507A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763948 | c.579G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763960 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763963 | c.594C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764089 | c.720C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764099 | p.Leu244Ile | missense_variant | 1.0 | rifampicin | |
rpoC | 764113 | c.744C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Asn | missense_variant | 1.0 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 764217 | p.Asn283Ser | missense_variant | 1.0 | rifampicin | |
rpoC | 764245 | c.876C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764248 | c.879C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764254 | c.885G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764317 | c.948C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764326 | c.957G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764665 | c.1296C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764749 | c.1380G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764833 | c.1464A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764962 | c.1593G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765016 | c.1647C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765085 | c.1716T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765121 | c.1752G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765413 | p.Pro682Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765691 | c.2322G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765694 | c.2325G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765724 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365_2367delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 765739 | c.2370G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766021 | c.2652G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766081 | c.2712T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 766087 | c.2718C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766366 | c.2997C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766387 | c.3018C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766489 | c.3120G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
rpoC | 766627 | c.3258G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766642 | c.3273C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766795 | c.3426C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767074 | c.3705T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767152 | c.3783T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767242 | p.Gln1291His | missense_variant | 1.0 | rifampicin | |
rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767275 | c.3906T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767302 | c.3933C>G | synonymous_variant | 1.0 | rifampicin | |
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775915 | p.Ala856Ser | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
rpsL | 781608 | c.49_51delAGTinsGC | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781742 | c.183C>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781820 | c.261G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 1.0 | streptomycin | |
rplC | 800600 | c.-209G>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800690 | c.-119C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800708 | c.-101C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800798 | c.-11_-8delTGGAinsC | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800806 | c.-3G>A | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800808 | c.-1A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800815 | c.7C>A | synonymous_variant | 1.0 | linezolid | |
rplC | 800820 | c.12G>A | synonymous_variant | 1.0 | linezolid | |
rplC | 800826 | c.18T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800829 | c.21C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800856 | c.48A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
rplC | 800872 | c.64_66delAGAinsCG | frameshift_variant&synonymous_variant | 1.0 | linezolid | |
rplC | 800877 | c.69A>T | synonymous_variant | 1.0 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801183 | c.375C>A | synonymous_variant | 1.0 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801249 | c.441T>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801387 | c.579G>C | synonymous_variant | 1.0 | linezolid | |
fbiC | 1303980 | c.1050G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303998 | c.1068T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304013 | c.1083G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304025 | c.1095C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304049 | c.1119T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304050 | c.1120T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304068 | p.Val380Ile | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304079 | c.1149A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304082 | c.1152C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304085 | c.1155C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304104 | c.1174C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304115 | c.1185A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>T | synonymous_variant | 0.82 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304911 | c.1981C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304922 | c.1992C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304949 | c.2019C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304970 | c.2040G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305042 | c.2112A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305066 | c.2136T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305069 | c.2139G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305075 | c.2145T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305078 | c.2148A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305092 | p.Ala721Gly | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305114 | c.2184T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305117 | c.2187T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305126 | c.2196T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305150 | c.2220C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305173 | p.Asn748Ser | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305177 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305181 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305273 | c.2343C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305276 | c.2346G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364898 | c.486C>T | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364916 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
atpE | 1460804 | c.-241T>C | upstream_gene_variant | 1.0 | bedaquiline | |
atpE | 1460807 | c.-238C>T | upstream_gene_variant | 1.0 | bedaquiline | |
atpE | 1460816 | c.-229T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rrs | 1473290 | n.1445delCinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476711 | n.3054G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476719 | n.3062C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476740 | n.3083G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673931 | c.-271C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673941 | p.Ala168Ser | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673946 | c.-256C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673949 | c.-253G>A | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673976 | c.-226T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673982 | c.-220G>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
fabG1 | 1674006 | p.Asp189Glu | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674729 | c.528G>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674738 | c.537C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674742 | p.Lys181Pro | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674750 | c.549T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674771 | c.570C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674774 | c.573A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674819 | c.618G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
rpsA | 1833250 | c.-292A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
rpsA | 1833256 | c.-286C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
rpsA | 1833262 | c.-280T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
rpsA | 1833265 | c.-277A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
rpsA | 1833268 | c.-274C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
rpsA | 1833589 | c.48A>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833604 | c.63C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834051 | c.510G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834102 | c.561T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834258 | c.717G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834297 | c.756C>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834387 | c.846C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834459 | c.918G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834558 | c.1017C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834561 | c.1020C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834570 | c.1029C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834612 | c.1071G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834657 | c.1116G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834753 | c.1212T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834759 | c.1218A>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Asn | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834798 | c.1257C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834810 | c.1269C>T | synonymous_variant | 1.0 | pyrazinamide | |
tsnR | 1853370 | c.-236_-234delGCAinsTC | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853387 | c.-219T>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853411 | c.-195C>T | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853485 | c.-121G>C | upstream_gene_variant | 1.0 | linezolid | |
tsnR | 1853489 | c.-117C>T | upstream_gene_variant | 1.0 | linezolid | |
ndh | 2101804 | c.1239T>G | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101808 | p.Thr412Ser | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101812 | p.Ile411Val | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101819 | c.1224G>A | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101830 | p.Ile405Val | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101837 | p.Ala402Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
delamanid | ||||||
isoniazid | Uncertain significance | |||||
ndh | 2101858 | p.Ile395Met | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101873 | c.1170T>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101876 | c.1167C>G | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101888 | c.1153_1155delGTTinsCG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
delamanid | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
ndh | 2101891 | c.1152C>G | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2101894 | c.1149T>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101939 | c.1104A>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101966 | c.1077T>G | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101969 | p.Glu358Asp | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101980 | p.Asn355Asp | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101988 | p.Ala352Asp | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102305 | c.738T>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102310 | c.733C>T | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102718 | p.Gln109Glu | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102728 | c.315T>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102736 | c.307T>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102737 | p.Glu102Asp | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102750 | p.Cys98Phe | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102755 | c.288G>C | synonymous_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102758 | p.Ala95Glu | missense_variant | 1.0 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
katG | 2155670 | c.442C>T | synonymous_variant | 1.0 | isoniazid | |
katG | 2155680 | c.432G>C | synonymous_variant | 1.0 | isoniazid | |
katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
katG | 2155695 | p.Ala139Val | missense_variant | 1.0 | isoniazid | |
katG | 2155704 | c.408C>G | synonymous_variant | 1.0 | isoniazid | |
katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2517959 | c.-156C>T | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518245 | p.His44Arg | missense_variant | 1.0 | isoniazid | |
kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
kasA | 2518255 | c.141A>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518279 | c.165T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518283 | c.169_171delGCGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | |
kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518300 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518312 | p.Asp66Glu | missense_variant | 1.0 | isoniazid | |
kasA | 2518315 | c.201G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518323 | p.Ser70Asn | missense_variant | 1.0 | isoniazid | |
kasA | 2518334 | c.220_222delCGAinsAG | frameshift_variant&synonymous_variant | 1.0 | isoniazid | |
kasA | 2518343 | p.Met77Leu | missense_variant | 1.0 | isoniazid | |
kasA | 2518348 | c.234A>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518594 | c.480C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518603 | c.489G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518645 | c.531G>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518651 | c.537C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518666 | c.552G>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518669 | c.555C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518759 | c.645C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518780 | c.666G>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518789 | c.675G>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518798 | c.684G>T | synonymous_variant | 1.0 | isoniazid | |
folC | 2746464 | p.Leu379Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747314 | c.285A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747330 | p.His90Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747341 | c.258C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747365 | c.234G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747395 | c.204T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747398 | c.201C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747412 | p.Ser63Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747413 | p.Arg62Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747419 | c.180C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747425 | c.174C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747442 | c.157T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747443 | c.156G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747467 | p.Asp44Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747473 | p.Arg42Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747479 | c.120G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747482 | c.117G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782495 | p.Asp516Glu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782504 | c.1539G>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782549 | c.1494T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782570 | c.1473C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782573 | c.1470C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782633 | c.1410G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782639 | c.1404A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782900 | c.1143C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Gln | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782960 | c.1083C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782987 | c.1056C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783071 | c.972C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783080 | c.963G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783083 | c.960G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783119 | c.924G>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783215 | c.828G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783218 | c.825C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783286 | p.Ala253Ser | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783287 | c.756C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783407 | c.636C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783419 | c.624G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783425 | c.618C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783499 | c.544T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783509 | c.534C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783557 | c.486T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783596 | c.447C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783611 | c.432C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783626 | c.415_417delGCGinsTC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783788 | c.255T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783791 | c.252C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783821 | c.222A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783860 | p.Asp61Glu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783872 | c.171G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783950 | c.93C>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
pepQ | 2859704 | c.715T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859723 | c.696T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | ||||||
pepQ | 2859735 | c.684G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859765 | c.654G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859771 | c.648T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859778 | p.Val214Asp | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859780 | p.Gln213Ala | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859787 | p.Val211Ala | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859801 | c.618G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859813 | c.606C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
Rv2681 | 2996984 | c.246C>G | synonymous_variant | 1.0 | capreomycin | |
Rv2681 | 2996987 | c.249A>G | synonymous_variant | 1.0 | capreomycin | |
Rv2681 | 2996990 | c.252G>C | synonymous_variant | 1.0 | capreomycin | |
Rv2681 | 2997013 | p.Gly92Ala | missense_variant | 1.0 | capreomycin | |
Rv2681 | 2997021 | c.283T>C | synonymous_variant | 1.0 | capreomycin | |
Rv2752c | 3065418 | c.774A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065457 | c.735A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065481 | c.711T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065487 | c.705T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065490 | c.702A>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065493 | c.699G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065496 | c.696G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065499 | c.693A>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065508 | c.684T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065511 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065517 | c.675C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065528 | c.664C>T | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065532 | c.660A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065541 | c.651A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065553 | c.639A>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065562 | c.630T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065576 | p.Ala206Ser | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065577 | c.615C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065580 | c.612G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065610 | c.580_582delACCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065619 | c.573C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065625 | c.567G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065634 | c.558G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065637 | c.555A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065640 | c.552T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065649 | c.543T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065666 | c.526T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065667 | c.525A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065675 | p.Phe173Leu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066926 | c.-735A>C | upstream_gene_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066927 | c.-736A>G | upstream_gene_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066933 | c.-743_-742delGGinsAC | upstream_gene_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067784 | c.162C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067817 | c.129C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067898 | p.Asp16Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067901 | c.45C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
ald | 3087750 | p.Tyr311Val | missense_variant | 1.0 | cycloserine | |
ald | 3087779 | c.960T>C | synonymous_variant | 1.0 | cycloserine | |
whiB7 | 3569178 | c.-499C>G | upstream_gene_variant | 1.0 | streptomycin | |
amikacin | ||||||
kanamycin | ||||||
whiB7 | 3569245 | c.-566C>G | upstream_gene_variant | 1.0 | streptomycin | |
amikacin | ||||||
kanamycin | ||||||
whiB7 | 3569250 | c.-571T>C | upstream_gene_variant | 1.0 | streptomycin | |
amikacin | ||||||
kanamycin | ||||||
lpqB | 3623756 | c.1155G>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623771 | c.1140C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624071 | c.840C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624077 | c.834G>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624082 | c.829A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624089 | c.822C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624094 | c.817A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624100 | c.811T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624101 | c.810C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624107 | c.804C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624116 | c.795A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624125 | c.786A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624133 | c.778A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624166 | p.Met249Leu | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624167 | c.744C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624172 | p.Val247Ile | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624173 | c.738A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624176 | c.735G>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624188 | c.723G>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624192 | p.Arg240Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
lpqB | 3624194 | c.717C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624200 | c.711A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624204 | p.Ser236Asn | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624209 | c.702A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624224 | c.687T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624323 | c.588G>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624339 | p.Arg191His | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624341 | c.570C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624346 | p.Ser189Ala | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624362 | c.549G>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624371 | c.540T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624389 | c.522C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624407 | c.504C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624698 | c.213G>A | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624701 | c.210T>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624731 | c.180C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625198 | c.-288C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625579 | c.-669A>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625615 | p.Arg333Ala | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3625762 | c.852A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625867 | c.747A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625891 | c.-981G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625915 | c.699G>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.92 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626882 | c.-269G>A | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626888 | c.460_462delTTGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626999 | c.-386G>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627122 | c.-509T>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627143 | c.-530G>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627170 | c.-557C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627188 | c.160_162delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627200 | c.-587C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627208 | c.142C>T | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627227 | c.-614T>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627233 | c.-620T>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627254 | c.-641C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
fbiB | 3640782 | c.-753C>G | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiA | 3640785 | p.Gln81His | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640788 | c.-747T>C | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640797 | c.-738T>A | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiA | 3640808 | p.Met89Lys | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiA | 3640810 | p.Gln90Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640816 | c.-719C>T | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiA | 3640820 | p.Val93Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640827 | c.-708T>C | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiA | 3640849 | p.Glu103Gln | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640857 | c.-678G>C | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640866 | c.-669T>C | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiA | 3640871 | p.Ala110Gly | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3640878 | c.-657T>C | upstream_gene_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
alr | 3841018 | p.Leu135Val | missense_variant | 1.0 | cycloserine | |
alr | 3841033 | p.Val130Ile | missense_variant | 1.0 | cycloserine | |
alr | 3841036 | p.Gln129Glu | missense_variant | 1.0 | cycloserine | |
alr | 3841041 | p.Asp127Gly | missense_variant | 1.0 | cycloserine | |
alr | 3841055 | c.366C>G | synonymous_variant | 1.0 | cycloserine | |
alr | 3841079 | c.342T>C | synonymous_variant | 1.0 | cycloserine | |
rpoA | 3877545 | c.963G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877567 | p.Ser314Thr | missense_variant | 1.0 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877773 | c.735G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877785 | c.723C>A | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877968 | c.540C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878019 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878046 | c.462T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878082 | c.426T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878088 | c.420C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878262 | c.244_246delAGCinsGT | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878301 | c.207C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878415 | c.93C>T | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878432 | c.76C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878458 | p.Asn17Thr | missense_variant | 1.0 | rifampicin | |
rpoA | 3878472 | c.36C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878490 | c.18C>A | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878728 | c.-221G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsGGC | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878842 | c.-335G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878845 | c.-338G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878890 | c.-383C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878893 | c.-388_-386delCACinsAG | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878926 | c.-419C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878962 | c.-455G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879037 | c.-530G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879079 | c.-572A>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879130 | c.-623A>G | upstream_gene_variant | 0.9 | rifampicin | |
rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 1.0 | rifampicin | |
ddn | 3986978 | c.135G>C | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987015 | p.Gln58Glu | missense_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987020 | c.177G>C | synonymous_variant | 0.93 | delamanid | |
pretomanid | ||||||
ddn | 3987023 | c.180G>C | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987028 | p.Asn62Ser | missense_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987035 | c.192C>G | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987042 | c.199C>T | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987053 | c.210T>C | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987055 | p.Gly71Asp | missense_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987062 | c.219C>G | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987065 | c.222T>C | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987089 | c.246G>C | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3987091 | p.Glu83Ala | missense_variant | 1.0 | delamanid | Uncertain significance |
pretomanid | ||||||
ddn | 3987113 | c.270C>G | synonymous_variant | 1.0 | delamanid | |
pretomanid | ||||||
clpC1 | 4038212 | c.2493T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038230 | c.2475G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038239 | c.2466T>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038242 | p.Thr821Val | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038248 | c.2457C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038271 | p.Pro812Ala | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038272 | c.2433T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038278 | c.2427T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038302 | c.2403C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038308 | c.2397G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038314 | c.2391T>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038317 | c.2388G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038329 | c.2376G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038347 | c.2358G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038350 | c.2355C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038436 | p.Ala757Ser | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038440 | c.2265C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038461 | c.2244G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Thr | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038488 | c.2217C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038498 | p.Ser736Thr | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038559 | p.Ile716Val | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038560 | p.Asp715Glu | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038857 | c.1848C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038884 | c.1821C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039031 | c.1674T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039259 | c.1446G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039286 | c.1417_1419delCTTinsAG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039316 | c.1389G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039322 | c.1383T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039406 | c.1299G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039433 | c.1272C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039544 | c.1161C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039568 | p.Met379Ile | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
clpC1 | 4039571 | c.1134G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039574 | p.Ala377Gly | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039581 | p.Thr375Ser | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039673 | c.1032G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039925 | c.779_780delGCinsTCGAGG | frameshift_variant&synonymous_variant | 0.91 | pyrazinamide | |
clpC1 | 4039927 | c.774_777delTAGC | frameshift_variant | 1.0 | pyrazinamide | |
clpC1 | 4039934 | c.771G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039996 | p.Glu237Gln | missense_variant | 0.94 | pyrazinamide | |
clpC1 | 4040021 | c.684A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4040057 | c.648C>T | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040285 | c.420G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4040342 | c.363C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040444 | c.261C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040669 | c.36C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040695 | c.10C>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040708 | c.-4A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
clpC1 | 4040711 | c.-7G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
panD | 4044024 | c.258T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044033 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044036 | c.246G>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044042 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044050 | c.232T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044051 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
panD | 4044057 | c.225C>G | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044063 | c.219T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
panD | 4044072 | c.210C>T | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044075 | c.207T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044081 | c.201T>G | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044084 | p.Ser66Thr | missense_variant | 1.0 | pyrazinamide | |
panD | 4044120 | c.162A>G | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044123 | c.159T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044126 | c.156T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044138 | c.144T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
panD | 4044150 | c.132A>G | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044162 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044165 | c.117G>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044180 | p.Asp34Glu | missense_variant | 1.0 | pyrazinamide | |
panD | 4044195 | c.87T>C | synonymous_variant | 1.0 | pyrazinamide | |
panD | 4044744 | c.-463T>A | upstream_gene_variant | 1.0 | pyrazinamide | |
panD | 4044746 | c.-465G>T | upstream_gene_variant | 1.0 | pyrazinamide | |
glpK | 4138292 | c.1464A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138298 | c.1458G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138311 | p.Arg482Gln | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138337 | p.Ala473Asp | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138352 | c.1404C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138360 | c.1396T>C | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138361 | c.1395C>G | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138376 | p.Val460Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
glpK | 4138379 | c.1377T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138382 | c.1374A>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138385 | c.1371A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138418 | c.1338T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138424 | c.1332T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138429 | c.1327T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138433 | c.1323C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138451 | c.1305T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138466 | c.1290C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138472 | c.1284G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138478 | c.1278T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138481 | c.1275G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138490 | c.1266G>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138495 | p.Gln421Glu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138496 | c.1260G>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138502 | c.1254T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138511 | c.1245C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138514 | c.1242A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138517 | c.1237_1239delGAAinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138523 | c.1233C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138562 | c.1194G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138568 | c.1188A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138586 | c.1170C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138610 | c.1146C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138625 | c.1131G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138628 | c.1128T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138685 | c.1071C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138706 | c.1050C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138714 | p.Ala348Ser | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138733 | c.1023C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138757 | c.997_999delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138781 | c.973_975delGTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138787 | c.969C>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138796 | c.960A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138808 | c.948G>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139312 | c.444T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139315 | c.441C>T | synonymous_variant | 0.93 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139318 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139321 | c.435T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139324 | c.432A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139339 | c.417G>C | synonymous_variant | 0.91 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139588 | c.168G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139594 | c.162C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139600 | c.156G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139630 | c.126C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139642 | c.114G>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139648 | c.108T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139653 | p.His35Asp | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
embC | 4240543 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240544 | p.Pro228Thr | missense_variant | 1.0 | ethambutol | |
embC | 4240547 | c.685C>T | synonymous_variant | 1.0 | ethambutol | |
embC | 4240558 | c.696C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240561 | c.699C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240576 | c.714A>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240578 | p.Ala239Val | missense_variant | 1.0 | ethambutol | |
embC | 4240582 | c.720C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240585 | c.723C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240587 | p.Gly242Ala | missense_variant | 1.0 | ethambutol | |
embC | 4240600 | c.738G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240603 | c.741G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240610 | p.Ile250Val | missense_variant | 1.0 | ethambutol | |
embC | 4240630 | c.768C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240632 | p.Met257Thr | missense_variant | 1.0 | ethambutol | |
embC | 4240642 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240645 | c.783G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240669 | c.807G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240670 | p.Thr270Val | missense_variant | 1.0 | ethambutol | |
embC | 4240675 | c.813C>T | synonymous_variant | 1.0 | ethambutol | |
embC | 4240678 | c.816T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 1.0 | ethambutol | |
embC | 4240690 | c.828G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240693 | c.831T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240707 | p.Val282Ala | missense_variant | 1.0 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4240735 | c.873C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240756 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240771 | c.909G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240828 | c.966G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240859 | p.Leu333Val | missense_variant | 1.0 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4240900 | c.1038A>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240924 | c.1062C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240936 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241023 | c.1161T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241084 | c.1222C>T | synonymous_variant | 1.0 | ethambutol | |
embC | 4241101 | c.1239G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241104 | c.1242G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241140 | c.1278A>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241665 | c.1803G>T | synonymous_variant | 1.0 | ethambutol | |
embC | 4241671 | c.1809T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241691 | p.Gly610Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
embC | 4241695 | c.1833T>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241704 | c.1842C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241713 | c.1851G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241719 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241741 | c.1879_1881delGTCinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
embA | 4244666 | c.1434G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244669 | c.1437G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244675 | c.1443A>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244681 | c.1449A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embA | 4244921 | c.1689C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244930 | c.1698G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244933 | c.1701A>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244960 | c.1728A>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244978 | c.1746G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244980 | p.Val583Ala | missense_variant | 1.0 | ethambutol | |
embA | 4244982 | c.1750T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244987 | c.1755T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244996 | c.1764C>T | synonymous_variant | 1.0 | ethambutol | |
embA | 4245050 | c.1818C>T | synonymous_variant | 0.88 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 0.83 | ethambutol | |
embA | 4245083 | c.1851A>G | synonymous_variant | 0.87 | ethambutol | Not assoc w R - Interim |
embA | 4245086 | c.1854C>G | synonymous_variant | 0.87 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.87 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 0.87 | ethambutol | |
embA | 4245093 | p.Ile621Val | missense_variant | 0.87 | ethambutol | Uncertain significance |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.88 | ethambutol | |
embA | 4245128 | c.1896G>C | synonymous_variant | 0.89 | ethambutol | |
embA | 4245131 | c.1899G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embA | 4245136 | p.Tyr635Trp | missense_variant | 1.0 | ethambutol | |
embA | 4245140 | c.1908C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embA | 4245152 | c.1920C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4245158 | c.1926C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4245164 | c.1932C>T | synonymous_variant | 1.0 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 1.0 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 1.0 | ethambutol | |
embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247875 | c.1362G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247899 | p.Met462Ile | missense_variant | 1.0 | ethambutol | |
embB | 4247909 | c.1396T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247920 | c.1407T>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4247938 | c.1425G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 1.0 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247950 | c.1437G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247951 | c.1438_1440delTCGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247971 | c.1458C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4247983 | c.1470G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248025 | c.1512A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
embB | 4248052 | c.1539G>A | synonymous_variant | 1.0 | ethambutol | |
embB | 4248055 | c.1542G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248064 | c.1551G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248253 | c.1740C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248277 | c.1764G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249369 | c.2856T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249375 | c.2862G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249381 | c.2868A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249387 | p.Glu958Asp | missense_variant | 1.0 | ethambutol | |
embB | 4249411 | c.2898G>A | synonymous_variant | 1.0 | ethambutol | |
embB | 4249417 | c.2904A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249423 | p.Asp970Glu | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4249432 | c.2919A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249441 | c.2928A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4249444 | c.2931T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249447 | c.2934G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249486 | c.2973T>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249487 | c.2974T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249492 | c.2979C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249505 | p.Gln998Lys | missense_variant | 1.0 | ethambutol | |
embB | 4249523 | c.3010_3012delAATinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
embB | 4249529 | p.Ile1006Val | missense_variant | 1.0 | ethambutol | |
embB | 4249532 | p.Ala1007Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4249537 | c.3024A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249558 | c.3045A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249568 | p.Ser1019Asn | missense_variant | 1.0 | ethambutol | |
embB | 4249573 | c.3060T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249581 | p.Leu1023Gln | missense_variant | 1.0 | ethambutol | |
embB | 4249594 | c.3081G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249600 | c.3087A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249607 | p.Thr1032Val | missense_variant | 1.0 | ethambutol | |
embB | 4249624 | c.3111C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249627 | c.3114G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249640 | c.3127T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4249648 | c.3135G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249657 | c.3144C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249661 | p.Ala1050Ser | missense_variant | 1.0 | ethambutol | |
embB | 4249686 | p.Ala1058Gly | missense_variant | 1.0 | ethambutol | |
embB | 4249693 | c.3180T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4249699 | c.3186T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4249702 | c.3189C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249717 | p.Asp1068Glu | missense_variant | 1.0 | ethambutol | |
embB | 4249720 | c.3207C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249721 | c.3208_3210delCTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
embB | 4249725 | p.Val1071Ala | missense_variant | 1.0 | ethambutol | |
embB | 4249734 | p.Pro1074Gln | missense_variant | 1.0 | ethambutol | |
embB | 4249741 | c.3228C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249750 | p.Glu1079Asp | missense_variant | 1.0 | ethambutol | |
embB | 4249751 | c.3238T>C | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267253 | c.1584T>C | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267256 | c.1581C>G | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267262 | c.1575T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
aftB | 4267266 | p.Ala524Gly | missense_variant | 1.0 | ethambutol | |
aftB | 4267268 | c.1569T>C | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267274 | c.1563G>C | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267290 | p.Ala516Gln | missense_variant | 1.0 | ethambutol | |
aftB | 4267295 | c.1540_1542delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
aftB | 4267305 | p.Val511Ala | missense_variant | 1.0 | ethambutol | |
aftB | 4267310 | c.1527G>T | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267316 | c.1521A>G | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267559 | c.1278C>G | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267571 | c.1266T>C | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267592 | c.1245C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
aftB | 4267619 | c.1218C>A | synonymous_variant | 1.0 | ethambutol | |
aftB | 4267625 | c.1212T>C | synonymous_variant | 1.0 | ethambutol | |
ubiA | 4269059 | p.Ile259Val | missense_variant | 0.86 | ethambutol | Uncertain significance |
ubiA | 4269075 | c.757_759delATTinsGC | frameshift_variant&missense_variant | 0.85 | ethambutol | |
ubiA | 4269088 | p.Ala249Val | missense_variant | 0.83 | ethambutol | Uncertain significance |
aftB | 4269123 | c.-287T>G | upstream_gene_variant | 0.85 | ethambutol | |
aftB | 4269143 | c.-307T>C | upstream_gene_variant | 0.88 | ethambutol | |
ubiA | 4269144 | c.690C>G | synonymous_variant | 0.88 | ethambutol | Not assoc w R - Interim |
ubiA | 4269164 | p.Leu224Met | missense_variant | 0.87 | ethambutol | |
aftB | 4269183 | c.-347T>C | upstream_gene_variant | 1.0 | ethambutol | |
aftB | 4269192 | c.-356C>G | upstream_gene_variant | 1.0 | ethambutol | |
ubiA | 4269222 | c.612T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
ethA | 4326942 | p.Ile178Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
ethA | 4326949 | p.Ala175Gly | missense_variant | 1.0 | ethionamide | |
ethA | 4326953 | p.Asp174Ala | missense_variant | 1.0 | ethionamide |