TB-Profiler result

Run: SRR12416840
Summary

Run ID: SRR12416840

Sample name:

Date: 2024-10-04T15:14:23.319158

Number of reads: 5197564

Percentage reads mapped: 67.7

Median coverage: 152.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: MDR-TB

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.14
lineage4 Euro-American None 0.93
lineage6.2.3 West-Africa 2 RD702 0.07
lineage4.9 Euro-American (H37Rv-like) None 0.93
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser450Leu Assoc w R
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.Met306Ile Assoc w R
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761155 p.Ser450Leu missense_variant 0.68 rifampicin Assoc w R
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance Mutation from literature
katG 2155168 p.Ser315Thr missense_variant 0.97 isoniazid Assoc w R High-level resistance
embB 4247431 p.Met306Ile missense_variant 0.85 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 819 c.819C>T synonymous_variant 0.16 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.17 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.17 isoniazid
dnaA 894 c.894G>A synonymous_variant 0.16 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.17 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.18 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.19 isoniazid
dnaA 996 c.996A>T synonymous_variant 0.19 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>A synonymous_variant 0.18 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.18 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.19 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.18 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.18 isoniazid
dnaA 1062 c.1062C>G synonymous_variant 0.21 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.23 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.24 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.24 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.24 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.23 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.23 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.23 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.24 isoniazid
dnaA 1158 c.1158C>T synonymous_variant 0.23 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.23 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.25 isoniazid
dnaA 1185 c.1185C>G synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 1188 c.1188G>A synonymous_variant 0.23 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.23 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.24 isoniazid
dnaA 1218 c.1218C>G synonymous_variant 0.22 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.21 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.23 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.22 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.22 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.23 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.21 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.2 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.18 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 0.18 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.18 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.17 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.17 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.17 isoniazid
gyrB 6169 c.930C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6178 c.939C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.26 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6334 c.-968G>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.24 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.26 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6892 c.-410C>T upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6901 c.-401G>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.2 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7000 c.-302C>T upstream_gene_variant 0.16 levofloxacin
moxifloxacin
gyrA 7093 c.-209T>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>A upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7198 c.1959C>A synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.22 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8096 c.795T>A synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.21 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8318 c.1017C>G synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8330 c.1029C>G synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.23 levofloxacin
moxifloxacin
gyrA 8402 c.1101C>T synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8528 c.1227G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8543 c.1242C>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8570 p.Glu423Asp missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8730 p.Gly477Arg missense_variant 0.19 levofloxacin Uncertain significance
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.21 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>T synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Ser missense_variant 0.19 levofloxacin
moxifloxacin
gyrA 8762 c.1461G>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.22 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8818 p.Ser506Asn missense_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.18 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9065 c.1764C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.21 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9146 c.1845C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9153 p.Thr618Asp missense_variant 0.17 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 0.17 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9233 c.1932C>G synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.21 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 0.21 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9329 c.2028C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
fgd1 491106 c.324T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491142 c.360C>T synonymous_variant 0.21 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491144 p.Ala121Asp missense_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.19 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491296 p.Val172Ile missense_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491302 p.Ile174Val missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491307 c.525C>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
mshA 575623 c.276C>G synonymous_variant 0.18 isoniazid
ethionamide
mshA 575629 c.282A>G synonymous_variant 0.18 isoniazid
ethionamide
mshA 575638 c.291T>C synonymous_variant 0.17 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.17 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 0.18 isoniazid
ethionamide
mshA 575674 c.327G>C synonymous_variant 0.2 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.22 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>G synonymous_variant 0.22 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.23 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.23 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.25 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.26 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.26 isoniazid
ethionamide
mshA 575749 c.402C>A synonymous_variant 0.26 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.25 isoniazid
ethionamide
mshA 575770 c.423G>A synonymous_variant 0.26 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.26 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.27 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.27 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 575812 c.465C>T synonymous_variant 0.24 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.21 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.22 isoniazid
ethionamide
mshA 575830 c.483C>G synonymous_variant 0.21 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.2 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.21 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.18 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.18 isoniazid
ethionamide
ccsA 619528 c.-363C>G upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>C upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619555 c.-336C>G upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619572 c.-319T>A upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619574 c.-317G>A upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619584 c.-307A>T upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619594 c.-297G>C upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620254 p.Leu122Phe missense_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620265 c.375C>G synonymous_variant 0.18 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>C synonymous_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620659 c.769_771delCGCinsAGG synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620664 c.774C>T synonymous_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620682 c.792G>A synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620688 c.798G>C synonymous_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>G synonymous_variant 0.22 kanamycin
capreomycin
amikacin
Rv0565c 656219 p.His418Tyr missense_variant 0.15 ethionamide
Rv0565c 656243 p.Leu410Met missense_variant 0.16 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.17 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.17 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.18 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.2 ethionamide
hadA 732373 c.444G>A synonymous_variant 0.16 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.19 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.2 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.19 isoniazid
nusG 734403 c.150C>T synonymous_variant 0.2 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.2 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.22 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.22 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.27 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.28 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.27 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>C synonymous_variant 0.3 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>G synonymous_variant 0.32 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734547 c.294G>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.23 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.23 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.19 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.2 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
nusG 734847 c.594T>C synonymous_variant 0.22 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.21 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.2 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.2 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.2 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.2 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.19 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.19 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.18 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.24 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.25 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.26 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.32 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.28 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.28 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.28 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760346 c.540C>T synonymous_variant 0.28 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.28 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.28 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.27 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.25 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760519 p.Thr238Ser missense_variant 0.23 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.22 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.24 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.28 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.27 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.3 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.3 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.27 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.25 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.26 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.25 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.23 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.23 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.24 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.24 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 0.23 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.27 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.22 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.23 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.25 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.23 rifampicin
rpoB 760910 c.1104C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 0.28 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.31 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.29 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.28 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.3 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.32 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.32 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.32 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.33 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.3 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.23 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.2 rifampicin
rpoB 761373 p.Val523Gln missense_variant 0.18 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.18 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.22 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.28 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.31 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.29 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.26 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.18 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.2 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.22 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.21 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.21 rifampicin
rpoB 761789 c.1983G>C synonymous_variant 0.21 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.21 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.21 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.19 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.22 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.22 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.23 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.25 rifampicin
rpoB 761867 c.2061C>T synonymous_variant 0.25 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.26 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.26 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.23 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.23 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.22 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.23 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.25 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 0.24 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.25 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762026 c.2220G>C synonymous_variant 0.25 rifampicin
rpoB 762050 c.2244G>A synonymous_variant 0.25 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.23 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.26 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.25 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.26 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.28 rifampicin
rpoB 762221 c.2415G>A synonymous_variant 0.26 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.28 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.28 rifampicin
rpoB 762278 c.2472C>T synonymous_variant 0.26 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762299 c.2493G>C synonymous_variant 0.23 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.21 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762323 c.2517C>G synonymous_variant 0.23 rifampicin
rpoB 762329 c.2523G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.24 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.23 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.25 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.26 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.22 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.22 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.24 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.24 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.26 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.23 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.2 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.2 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 0.21 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.18 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.19 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.19 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.17 rifampicin
rpoB 762789 p.Leu995Met missense_variant 0.17 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.17 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.19 rifampicin Uncertain significance
rpoB 762810 p.Ala1002Ser missense_variant 0.18 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.19 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.32 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 763145 c.3339G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.22 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.23 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>A synonymous_variant 0.25 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.28 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.31 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.37 rifampicin
rpoC 763492 c.123G>T synonymous_variant 0.35 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.31 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.28 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.27 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.27 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.27 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.25 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.25 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.19 rifampicin
rpoC 763836 p.Ala156Val missense_variant 0.16 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.16 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763948 c.579G>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763954 c.585C>G synonymous_variant 0.17 rifampicin
rpoC 763963 c.594C>G synonymous_variant 0.19 rifampicin
rpoC 763969 c.600C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.19 rifampicin
rpoC 763993 p.Ile208Met missense_variant 0.17 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.19 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.18 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.18 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.19 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.18 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.19 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.2 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.21 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.22 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.23 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.23 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.21 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.2 rifampicin
rpoC 764272 c.903G>A synonymous_variant 0.21 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.18 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764362 c.993C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764381 p.Ser338Thr missense_variant 0.17 rifampicin
rpoC 764389 p.Leu340Phe missense_variant 0.17 rifampicin Uncertain significance
rpoC 764407 p.Arg346Ser missense_variant 0.17 rifampicin
rpoC 764419 c.1050C>G synonymous_variant 0.18 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.18 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.19 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764576 p.Ser403Thr missense_variant 0.16 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.16 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.18 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.23 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>C synonymous_variant 0.27 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.21 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.21 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764941 c.1572G>T synonymous_variant 0.17 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.18 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.19 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 0.2 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765371 c.2002C>T synonymous_variant 0.27 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.29 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.28 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.28 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.29 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.29 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.3 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.31 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.32 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.29 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.3 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.31 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.3 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.3 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.31 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.32 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.31 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.31 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.32 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765862 c.2493C>T synonymous_variant 0.32 rifampicin
rpoC 765883 c.2514C>G synonymous_variant 0.33 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.32 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.31 rifampicin
rpoC 765937 c.2568T>A synonymous_variant 0.31 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.29 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.27 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.28 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.3 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.31 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.31 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.29 rifampicin
rpoC 766070 c.2701C>T synonymous_variant 0.28 rifampicin Not assoc w R
rpoC 766081 c.2712T>C synonymous_variant 0.24 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.24 rifampicin
rpoC 766087 c.2718C>T synonymous_variant 0.24 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.24 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.24 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.21 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.17 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766327 c.2958C>A synonymous_variant 0.18 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.2 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.21 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.21 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.21 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.22 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.23 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.26 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.26 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.29 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.27 rifampicin
rpoC 766462 c.3093G>T synonymous_variant 0.22 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.19 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.18 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.18 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>G synonymous_variant 0.25 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.25 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.23 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.22 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.22 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.21 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.2 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.19 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.19 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.2 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.2 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.23 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.29 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.27 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.25 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.25 rifampicin
rpoC 766723 c.3354G>A synonymous_variant 0.3 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.3 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.33 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.34 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.33 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.29 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.31 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.31 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.32 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 0.33 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 766966 c.3597G>A synonymous_variant 0.32 rifampicin
rpoC 766972 c.3603G>C synonymous_variant 0.32 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.23 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.27 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.25 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.22 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.17 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.18 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.19 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.25 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.25 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.25 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.27 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.25 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.24 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.24 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.24 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.24 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.26 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.27 streptomycin
rpsL 781769 c.210G>A synonymous_variant 0.25 streptomycin
rpsL 781772 c.213C>G synonymous_variant 0.27 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.26 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.27 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.29 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.28 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.29 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.28 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.28 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.28 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.29 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.28 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.27 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.24 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.23 streptomycin Uncertain significance
rplC 800174 c.-635G>A upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.16 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.19 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.24 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.24 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.29 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.3 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.29 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.28 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.25 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.26 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.26 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.25 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.26 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.24 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.23 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.22 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 0.22 linezolid
rplC 800814 c.6A>G synonymous_variant 0.19 linezolid
rplC 800817 c.9A>T synonymous_variant 0.2 linezolid
rplC 800844 c.36T>C synonymous_variant 0.19 linezolid
rplC 801321 c.513C>T synonymous_variant 0.16 linezolid Not assoc w R - Interim
rplC 801367 p.Ala187Thr missense_variant 0.16 linezolid
rplC 801402 c.594T>C synonymous_variant 0.18 linezolid
rplC 801405 c.597T>C synonymous_variant 0.18 linezolid
rplC 801423 c.615G>C synonymous_variant 0.19 linezolid
rplC 801426 c.618C>G synonymous_variant 0.19 linezolid
rplC 801427 p.Met207Val missense_variant 0.19 linezolid
rplC 801438 c.630T>C synonymous_variant 0.23 linezolid
rplC 801442 p.Ile212Val missense_variant 0.23 linezolid
fbiC 1303489 c.559C>T synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1303492 c.562T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1303501 c.571C>T synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303530 c.600G>A synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1303681 c.751T>C synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>T synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1303812 c.882C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>T synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1304727 c.1797A>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.17 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304958 c.2028T>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1305075 c.2145T>C synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1305092 p.Ala721Gly missense_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1305114 c.2184T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1305117 c.2187T>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 0.2 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1305150 c.2220C>G synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1305173 p.Asn748Ser missense_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1305177 c.2247A>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1305181 c.2251T>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1305187 c.2257C>T synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1305204 c.2274C>G synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1305215 p.Ser762Thr missense_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1305219 c.2289T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1305231 c.2301C>A synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1305252 c.2322G>A synonymous_variant 0.15 pretomanid
delamanid
clofazimine
sigE 1364950 p.Ala180Ser missense_variant 0.16 pyrazinamide
atpE 1461194 c.150C>T synonymous_variant 0.16 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.2 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.23 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.28 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.28 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.31 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445delCinsTT non_coding_transcript_exon_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.29 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.24 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.31 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.31 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
inhA 1673633 c.-569G>A upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673637 c.-565C>G upstream_gene_variant 0.2 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673652 c.-550C>G upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673657 c.-545C>A upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 0.2 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673941 c.-261G>T upstream_gene_variant 0.16 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.17 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.18 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.18 isoniazid
ethionamide
inhA 1674552 c.351C>G synonymous_variant 0.18 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.18 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.22 isoniazid
ethionamide
inhA 1674601 p.Leu134Ala missense_variant 0.2 isoniazid
ethionamide
inhA 1674609 c.408G>C synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674621 c.420C>G synonymous_variant 0.22 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.22 isoniazid
ethionamide
inhA 1674657 c.456C>T synonymous_variant 0.22 isoniazid
ethionamide
inhA 1674660 c.459G>T synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674669 c.468G>C synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674714 c.513C>G synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674723 c.522C>T synonymous_variant 0.19 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674726 c.525G>C synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674732 c.531C>T synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674738 c.537C>A synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 0.23 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.24 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.24 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.25 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674813 c.612C>T synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674816 c.615T>C synonymous_variant 0.26 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674840 c.639C>G synonymous_variant 0.25 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.25 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.18 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.18 isoniazid
ethionamide
rpsA 1833589 c.48A>T synonymous_variant 0.17 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.19 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.28 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.3 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.3 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.3 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.29 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.29 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.3 pyrazinamide
rpsA 1833790 c.249T>A synonymous_variant 0.3 pyrazinamide
rpsA 1833799 c.258C>T synonymous_variant 0.29 pyrazinamide
rpsA 1833805 c.264C>G synonymous_variant 0.28 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.28 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.31 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.31 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.32 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.31 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.29 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.33 pyrazinamide
rpsA 1833970 c.429G>A synonymous_variant 0.33 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.34 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.33 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.3 pyrazinamide
rpsA 1834066 c.525G>A synonymous_variant 0.24 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.21 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.2 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.21 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.23 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.19 pyrazinamide
rpsA 1834154 p.Asn205His missense_variant 0.17 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.24 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGT synonymous_variant 0.21 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 0.23 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.29 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.29 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.29 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.28 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.29 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.31 pyrazinamide
rpsA 1834499 c.958C>T synonymous_variant 0.32 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 0.35 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.34 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.36 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.39 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.33 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.34 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.35 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.35 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.34 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.29 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.28 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.28 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.25 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.25 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.29 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.27 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.29 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.31 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.33 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.29 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.26 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.24 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.21 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.18 linezolid
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1918383 c.444C>G synonymous_variant 0.97 capreomycin
bacA 2064993 c.-265T>C upstream_gene_variant 0.19 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101830 p.Ile405Val missense_variant 0.17 isoniazid
delamanid
ethionamide
ndh 2101837 p.Ala402Val missense_variant 0.17 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101849 c.1194G>C synonymous_variant 0.16 isoniazid
delamanid
ethionamide
ndh 2101920 c.1123A>C synonymous_variant 0.16 isoniazid
delamanid
ethionamide
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517923 c.-192C>G upstream_gene_variant 0.29 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.25 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.2 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.18 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.19 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.22 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.22 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.23 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.19 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.19 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.19 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.18 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.19 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.2 isoniazid
kasA 2518603 c.489G>C synonymous_variant 0.21 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.22 isoniazid
kasA 2518618 c.504G>T synonymous_variant 0.24 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.24 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.24 isoniazid
kasA 2518657 c.543G>A synonymous_variant 0.22 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.22 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.22 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.23 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.21 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.21 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.21 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.21 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.22 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.24 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.23 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.23 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.24 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.24 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.23 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.22 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.23 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.23 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.2 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.21 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.21 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.23 isoniazid
kasA 2518882 c.768C>G synonymous_variant 0.22 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.22 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.2 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.2 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.19 isoniazid
kasA 2518915 c.801T>C synonymous_variant 0.18 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.17 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.16 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.21 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.22 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 0.22 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.24 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.26 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.26 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.27 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.28 isoniazid
kasA 2519170 c.1056G>T synonymous_variant 0.29 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.3 isoniazid
kasA 2519206 c.1092C>T synonymous_variant 0.32 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.31 isoniazid
kasA 2519230 c.1116C>T synonymous_variant 0.29 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 0.26 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.26 isoniazid
kasA 2519260 c.1146T>G synonymous_variant 0.17 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 0.17 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 0.17 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 0.17 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.16 isoniazid
folC 2747023 c.576C>G synonymous_variant 0.22 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 0.18 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.18 para-aminosalicylic_acid
Rv2477c 2782936 c.1107G>A synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.19 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782960 c.1083C>G synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782966 c.1077C>T synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>T synonymous_variant 0.2 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782981 c.1062G>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.23 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.28 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783053 c.990C>T synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783065 c.978C>T synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.26 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.28 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.27 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783305 c.738G>A synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.16 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783497 p.Leu182Phe missense_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783521 c.522G>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.25 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783566 p.Asn159Lys missense_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783629 c.414C>T synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783673 c.370C>A synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.26 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783695 c.348C>T synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783853 c.190C>T synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.22 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.22 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.21 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.18 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784441 c.-399G>C upstream_gene_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3065993 p.Val67Ile missense_variant 0.17 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 0.16 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066009 c.183G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066071 c.121T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066537 c.-346C>T upstream_gene_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067457 c.489C>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067691 p.Ile85Leu missense_variant 0.21 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.25 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.26 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067853 c.93C>T synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.2 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.17 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.16 para-aminosalicylic_acid
thyA 3073878 c.594G>A synonymous_variant 0.17 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.22 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3073914 c.558C>T synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3073917 c.555C>A synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073983 c.489C>T synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.25 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.26 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3074100 c.372T>C synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074118 c.354G>A synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3074147 p.Ile109Val missense_variant 0.23 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074163 p.Ala103Thr missense_variant 0.19 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074199 c.273G>A synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.19 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074379 c.93C>T synonymous_variant 0.16 para-aminosalicylic_acid
thyA 3074391 c.81C>A synonymous_variant 0.16 para-aminosalicylic_acid
lpqB 3624077 c.834G>C synonymous_variant 0.17 rifampicin
bedaquiline
lpqB 3624086 c.825C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624094 c.817A>C synonymous_variant 0.19 rifampicin
bedaquiline
lpqB 3624101 c.810C>G synonymous_variant 0.17 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624116 c.795A>G synonymous_variant 0.18 rifampicin
bedaquiline
lpqB 3624124 p.Leu263Val missense_variant 0.17 rifampicin
bedaquiline
lpqB 3624146 c.765C>G synonymous_variant 0.2 rifampicin
bedaquiline
lpqB 3624185 c.726C>T synonymous_variant 0.15 rifampicin
bedaquiline
lpqB 3624431 c.480C>T synonymous_variant 0.18 rifampicin
bedaquiline
lpqB 3624728 c.183C>T synonymous_variant 0.17 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.156A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3625135 c.1479A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 0.18 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.2 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 0.2 rifampicin
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrB 3625206 p.Ser470Ala missense_variant 0.17 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 0.17 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.22 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrB 3625592 p.Ser341Asn missense_variant 0.24 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.24 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 0.22 rifampicin
bedaquiline
mtrB 3625636 c.978C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.25 rifampicin
bedaquiline
lpqB 3625696 c.-786A>G upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3625705 c.909C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.34 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625777 c.-867C>G upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.31 rifampicin Uncertain significance
bedaquiline Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625840 c.-930A>G upstream_gene_variant 0.24 rifampicin
bedaquiline
lpqB 3625843 c.-933C>G upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3625876 c.738G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626765 c.585C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrA 3626869 c.481C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrB 3626912 c.-299T>G upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrA 3626939 c.411A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3627005 c.-392G>C upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3627065 c.-452G>C upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627074 c.-461G>C upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627125 c.-512C>G upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrA 3627175 c.175C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627196 c.-583C>T upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.19 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.15 rifampicin
bedaquiline
alr 3840547 p.Gly292Ser missense_variant 0.18 cycloserine
alr 3840551 c.870G>C synonymous_variant 0.19 cycloserine
alr 3840575 c.846G>A synonymous_variant 0.19 cycloserine
alr 3840578 c.843T>G synonymous_variant 0.18 cycloserine
rpoA 3877535 p.Val325Ile missense_variant 0.87 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.19 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.25 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.26 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.26 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3877743 c.765T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877748 c.760C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.22 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.24 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.22 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.22 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.2 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.18 rifampicin
rpoA 3877899 p.Ser203Asn missense_variant 0.17 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.21 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.23 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.3 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.29 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.28 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>A synonymous_variant 0.28 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.28 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.28 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.27 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.27 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.26 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.28 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.26 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.25 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.25 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.26 rifampicin
rpoA 3878130 c.378C>A synonymous_variant 0.27 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.25 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.23 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.23 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.25 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.26 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.29 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.29 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.31 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Ala missense_variant 0.32 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.34 rifampicin
rpoA 3878313 c.195G>T synonymous_variant 0.35 rifampicin
rpoA 3878322 c.186A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.34 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.33 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.33 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.33 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.32 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.31 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.3 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.25 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.19 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.18 rifampicin
rpoA 3878683 c.-176G>C upstream_gene_variant 0.16 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.18 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 0.18 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 0.2 rifampicin
rpoA 3878716 c.-209C>G upstream_gene_variant 0.21 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.24 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.23 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.23 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.23 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.23 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.24 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.24 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.31 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.32 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.34 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.35 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.32 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.26 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.27 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.32 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.35 rifampicin Uncertain significance
rpoA 3878890 c.-383C>G upstream_gene_variant 0.36 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.36 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.34 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.32 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.31 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoA 3878953 c.-446C>T upstream_gene_variant 0.3 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.32 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.31 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.26 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.27 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.26 rifampicin
rpoA 3879033 c.-526C>T upstream_gene_variant 0.25 rifampicin
rpoA 3879034 c.-527G>A upstream_gene_variant 0.25 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.28 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.27 rifampicin
rpoA 3879085 c.-578C>T upstream_gene_variant 0.25 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.25 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.25 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.23 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.23 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.2 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.19 rifampicin
clpC1 4038356 c.2349T>C synonymous_variant 0.19 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.19 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.17 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.17 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.19 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.19 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.18 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.17 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.17 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.18 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.18 pyrazinamide
clpC1 4038487 p.Gly740Ser missense_variant 0.16 pyrazinamide
clpC1 4038498 p.Ser736Asn missense_variant 0.16 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.19 pyrazinamide
clpC1 4038539 c.2166G>C synonymous_variant 0.21 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.21 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.22 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.24 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.27 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.26 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.26 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.26 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.25 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.27 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.24 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.23 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.25 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.28 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.25 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.28 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.26 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.28 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.29 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.28 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.3 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.29 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.28 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.28 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.25 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.22 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.23 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.26 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.27 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.27 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.27 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>G synonymous_variant 0.26 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.27 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.27 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.27 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.27 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.26 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.28 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.32 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.32 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.31 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.28 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039457 c.1248C>G synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.23 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.26 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.25 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.25 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.25 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.24 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.25 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 0.24 pyrazinamide
clpC1 4039576 p.Ala377Pro missense_variant 0.24 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.28 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.31 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.3 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.28 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.27 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.26 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.25 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.27 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.25 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.25 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.27 pyrazinamide
clpC1 4039805 c.900C>A synonymous_variant 0.22 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.19 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.24 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.24 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.24 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.26 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.26 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.26 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.2 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.21 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.18 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.19 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.19 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.2 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.19 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.19 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.17 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.16 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.18 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.19 pyrazinamide
clpC1 4040459 c.246C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.18 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.18 pyrazinamide
clpC1 4040486 c.219G>C synonymous_variant 0.18 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
panD 4044700 c.-419C>A upstream_gene_variant 0.16 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 0.17 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.17 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.19 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.21 pyrazinamide
panD 4044746 c.-467_-465delGTGinsATC upstream_gene_variant 0.2 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.19 pyrazinamide
embC 4240543 c.681G>C synonymous_variant 0.17 ethambutol
embC 4240558 c.696C>G synonymous_variant 0.18 ethambutol
embC 4240561 c.699C>G synonymous_variant 0.18 ethambutol
embC 4240570 c.708C>G synonymous_variant 0.17 ethambutol
embC 4240578 p.Ala239Val missense_variant 0.16 ethambutol
embC 4240587 p.Gly242Ala missense_variant 0.18 ethambutol
embC 4240592 p.Ala244Ser missense_variant 0.19 ethambutol
embC 4240600 c.738G>C synonymous_variant 0.19 ethambutol
embC 4240610 p.Ile250Arg missense_variant 0.19 ethambutol
embC 4240615 c.753G>C synonymous_variant 0.21 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.25 ethambutol
embC 4240642 c.780G>C synonymous_variant 0.27 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.27 ethambutol
embC 4240670 p.Thr270Leu missense_variant 0.26 ethambutol
embC 4240678 c.816T>G synonymous_variant 0.27 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.26 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.25 ethambutol
embC 4240695 p.Ile278Thr missense_variant 0.25 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embC 4240759 c.897C>G synonymous_variant 0.3 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.26 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.27 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.28 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.28 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.27 ethambutol
embC 4240831 c.969T>C synonymous_variant 0.26 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.2 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.18 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.18 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.16 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.18 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.18 ethambutol Not assoc w R - Interim
embC 4241501 p.Ser547Thr missense_variant 0.17 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.18 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.21 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>A synonymous_variant 0.21 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.2 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 0.19 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.19 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.19 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.19 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.18 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.18 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.19 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.21 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.23 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.21 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.22 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.2 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.19 ethambutol
embC 4241647 c.1785G>A synonymous_variant 0.19 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embC 4241657 p.Ser599Pro missense_variant 0.17 ethambutol
embC 4242791 p.Ala977Ser missense_variant 0.16 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.17 ethambutol
embA 4242809 c.-424C>T upstream_gene_variant 0.2 ethambutol
embA 4242820 c.-413G>C upstream_gene_variant 0.22 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.23 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 0.24 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.24 ethambutol
embC 4242841 c.2979C>T synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4242844 c.-389A>G upstream_gene_variant 0.24 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.24 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.23 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.23 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embA 4242886 c.-347G>A upstream_gene_variant 0.22 ethambutol
embA 4242892 c.-341G>C upstream_gene_variant 0.23 ethambutol
embA 4242901 c.-332G>C upstream_gene_variant 0.23 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.2 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.3 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.3 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.3 ethambutol
embA 4245173 c.1941G>C synonymous_variant 0.32 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.31 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.28 ethambutol
embA 4245206 c.1974A>G synonymous_variant 0.26 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.26 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.26 ethambutol
embA 4245222 p.Tyr664Gln missense_variant 0.26 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.23 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embA 4245355 p.Ala708Gly missense_variant 0.16 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.18 ethambutol
embB 4246184 c.-330A>G upstream_gene_variant 0.17 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.16 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.17 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.18 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.2 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.23 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.21 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.2 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.19 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.18 ethambutol
embB 4247455 c.942C>A synonymous_variant 0.19 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.19 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.21 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.21 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.19 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.19 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.18 ethambutol
embB 4247521 c.1008G>C synonymous_variant 0.17 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.22 ethambutol
embB 4247764 c.1251G>C synonymous_variant 0.23 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.28 ethambutol
embB 4247776 c.1263G>C synonymous_variant 0.28 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.28 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.27 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.29 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.29 ethambutol Uncertain significance
embB 4247830 c.1317A>C synonymous_variant 0.31 ethambutol
embB 4247836 c.1323A>G synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embB 4247876 c.1363C>T synonymous_variant 0.32 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.3 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.25 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.24 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embB 4247914 c.1401G>C synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.18 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.19 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.18 ethambutol
embB 4248011 p.Ser500Pro missense_variant 0.17 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.17 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.2 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.2 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.2 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.2 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.23 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.22 ethambutol
embB 4248073 c.1560C>G synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embB 4248085 c.1572T>C synonymous_variant 0.21 ethambutol
embB 4248094 c.1581C>T synonymous_variant 0.2 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.2 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.23 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.24 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.25 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.23 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.23 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>G synonymous_variant 0.23 ethambutol
embB 4248172 c.1659G>C synonymous_variant 0.23 ethambutol
embB 4248199 c.1686A>C synonymous_variant 0.24 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.25 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.25 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.26 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.18 ethambutol
embB 4248382 c.1869C>G synonymous_variant 0.16 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.17 ethambutol
embB 4249486 c.2973T>A synonymous_variant 0.18 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.21 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.16 ethambutol
ubiA 4269075 p.Ile253Val missense_variant 0.19 ethambutol
aftB 4269081 c.-245G>C upstream_gene_variant 0.19 ethambutol
aftB 4269084 c.-248G>C upstream_gene_variant 0.19 ethambutol
aftB 4269102 c.-268_-266delAGCinsTCG upstream_gene_variant 0.18 ethambutol
ubiA 4269107 p.Tyr243His missense_variant 0.17 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.19 ethambutol
ubiA 4269131 c.703C>T synonymous_variant 0.19 ethambutol Not assoc w R - Interim
aftB 4269132 c.-296G>C upstream_gene_variant 0.19 ethambutol
aftB 4269138 c.-302C>T upstream_gene_variant 0.19 ethambutol
ubiA 4269141 p.Leu231Val missense_variant 0.18 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.18 ethambutol Not assoc w R - Interim
aftB 4269165 c.-329G>C upstream_gene_variant 0.18 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
gid 4407790 p.Ala138Glu missense_variant 1.0 streptomycin Uncertain significance