TB-Profiler result

Run: SRR6045371
Summary

Run ID: SRR6045371

Sample name:

Date: 2024-04-15T05:45:19.145557

Number of reads: 253399

Percentage reads mapped: 13.52

Median coverage: 4.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.2.1.1 Euro-American (TUR) None 0.1
lineage4.9 Euro-American (H37Rv-like) None 0.76
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.1774_1776delCACinsTT Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1304704 c.1774_1776delCACinsTT frameshift_variant&missense_variant 0.86 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 819 c.819C>T synonymous_variant 0.5 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.47 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.5 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.5 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.5 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.5 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.5 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.54 isoniazid Not assoc w R - Interim
gyrB 6178 c.939C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrB 6551 c.1312T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6556 c.-746C>T upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6631 c.-671C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 0.97 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6727 c.-575G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.97 levofloxacin Uncertain significance
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6775 c.-527G>T upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 6798 p.Gly520Ala missense_variant 0.83 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6808 c.1569C>G synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.76 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7006 c.-296T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 7010 p.Leu591Met missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.75 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>T upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>T upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7120 c.-182T>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrB 7126 c.1887G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7129 c.-173T>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>A upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 7159 c.1920C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7162 c.-140C>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7370 c.69G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7430 c.129G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7466 c.165G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7571 c.270G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7601 c.300C>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7640 c.339G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7643 c.342C>A synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7658 c.357A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7670 c.369A>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7671 c.370_372delCCGinsGC frameshift_variant&missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCT frameshift_variant&missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7698 c.397C>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7706 c.405C>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7725 c.424C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7831 c.531_532delGT frameshift_variant 0.79 levofloxacin
moxifloxacin
gyrA 7837 c.536_540delGCGGCinsCGGCGGT frameshift_variant&missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 7847 c.546G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7853 c.552C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7868 p.Ile189Met missense_variant 0.86 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.6 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Lys missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8993 c.1692C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.87 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9018 p.Gln573Lys missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9063 p.Ser588Ala missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
mshA 575734 c.387T>G synonymous_variant 0.53 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.5 ethionamide
isoniazid
mshA 575740 c.393G>A synonymous_variant 0.53 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.5 ethionamide
isoniazid Uncertain significance
mshA 575756 c.409C>T synonymous_variant 0.6 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.62 ethionamide
isoniazid
nusG 734445 c.192C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734452 c.199_201delGAAinsCG frameshift_variant&missense_variant 0.83 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734497 c.244_246delGTGinsAC frameshift_variant&missense_variant 0.81 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
nusG 734544 c.291C>T synonymous_variant 0.87 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.85 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.89 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.88 rifampicin Uncertain significance
rpoB 760276 p.Lys157Met missense_variant 0.88 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.94 rifampicin
rpoB 760370 c.564C>G synonymous_variant 0.94 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.94 rifampicin Uncertain significance
rpoB 760382 c.576G>C synonymous_variant 0.94 rifampicin
rpoB 760400 c.594G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.87 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.87 rifampicin Uncertain significance
rpoB 760412 c.606C>T synonymous_variant 0.87 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>A synonymous_variant 0.87 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760433 c.627C>T synonymous_variant 0.88 rifampicin
rpoB 760454 c.648C>G synonymous_variant 0.89 rifampicin
rpoB 760457 c.651C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760469 c.663C>T synonymous_variant 0.89 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.94 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 1.0 rifampicin
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.92 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>T synonymous_variant 0.85 rifampicin
rpoB 760561 c.757_758delCG frameshift_variant 0.77 rifampicin
rpoB 760567 c.761delCinsGGG frameshift_variant&missense_variant 0.77 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.79 rifampicin
rpoB 760588 p.Thr261Ile missense_variant 0.82 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.82 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.82 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.83 rifampicin
rpoB 760607 c.801G>C synonymous_variant 0.88 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760668 p.Thr288Ala missense_variant 0.81 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.8 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Leu missense_variant 0.8 rifampicin
rpoB 760877 c.1071G>C synonymous_variant 0.8 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.8 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.8 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.8 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.86 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.83 rifampicin Uncertain significance
rpoB 760973 c.1167G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.71 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.7 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.7 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761178 c.1372_1374delTCAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761186 p.Glu460Asp missense_variant 1.0 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761639 c.1833G>C synonymous_variant 0.75 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.79 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.79 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.81 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.8 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.86 rifampicin
rpoB 761690 c.1884G>T synonymous_variant 0.86 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.86 rifampicin
rpoB 761720 c.1914_1916delCGAinsGG frameshift_variant&synonymous_variant 0.92 rifampicin
rpoB 761727 p.Ser641Gly missense_variant 0.92 rifampicin
rpoB 761728 c.1923dupC frameshift_variant 0.92 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761741 c.1935G>A synonymous_variant 0.85 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.85 rifampicin
rpoB 761760 p.Ile652Val missense_variant 0.82 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.9 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>T synonymous_variant 0.83 rifampicin
rpoB 761955 p.Ile717Val missense_variant 0.83 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>T synonymous_variant 0.84 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.87 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.87 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.85 rifampicin
rpoB 762134 c.2328C>A synonymous_variant 0.85 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.85 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.81 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.82 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.91 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.8 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.7 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>A upstream_gene_variant 0.73 rifampicin
rpoB 762863 c.3057T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.88 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762911 c.-459C>T upstream_gene_variant 0.93 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.93 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763034 c.-336C>A upstream_gene_variant 0.94 rifampicin
rpoB 763040 c.3234C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.87 rifampicin
rpoB 763157 c.3351G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763187 c.-183C>G upstream_gene_variant 0.71 rifampicin
rpoB 763193 c.3387C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763365 c.-5_-4insT upstream_gene_variant 0.54 rifampicin Uncertain significance
rpoC 763375 c.6C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.72 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763415 c.46_48delACCinsTG frameshift_variant&missense_variant 0.76 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.72 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.74 rifampicin
rpoC 763450 c.81G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.91 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763687 c.318C>T synonymous_variant 0.92 rifampicin
rpoC 763699 c.330G>T synonymous_variant 0.92 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.92 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.86 rifampicin
rpoC 763714 c.345G>A synonymous_variant 0.83 rifampicin
rpoC 763717 c.348T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.83 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.86 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.78 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.76 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.55 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.73 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.73 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.73 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.73 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.73 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.73 rifampicin
rpoC 764077 c.708C>G synonymous_variant 0.69 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.69 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.69 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764104 c.735C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>T synonymous_variant 0.82 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.89 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.91 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764506 c.1137C>T synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 1.0 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.96 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>T synonymous_variant 0.97 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764719 c.1350G>A synonymous_variant 0.93 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764810 c.1441_1443delCCCinsGT frameshift_variant&missense_variant 0.91 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.97 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.87 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.86 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.87 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>A synonymous_variant 0.82 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.75 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.75 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.71 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.71 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.75 rifampicin
rpoC 765379 c.2010G>C synonymous_variant 0.58 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.58 rifampicin Uncertain significance
rpoC 765394 c.2025G>A synonymous_variant 0.71 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 0.68 rifampicin
rpoC 765405 p.Leu679His missense_variant 0.68 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765412 c.2043T>C synonymous_variant 0.76 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765449 c.2080_2082delGCCinsTG frameshift_variant&missense_variant 0.83 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765469 c.2100G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>G synonymous_variant 0.81 rifampicin
rpoC 765480 p.Tyr704Phe missense_variant 0.81 rifampicin Uncertain significance
rpoC 765496 c.2127C>T synonymous_variant 0.78 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.82 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.82 rifampicin Uncertain significance
rpoC 765861 p.Phe831Tyr missense_variant 0.85 rifampicin Uncertain significance
rpoC 765868 c.2499G>A synonymous_variant 0.89 rifampicin
rpoC 765871 c.2502T>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.85 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.85 rifampicin
rpoC 765907 c.2538G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.78 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.78 rifampicin
rpoC 765973 c.2604C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.63 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.69 rifampicin
rpoC 766522 c.3153C>A synonymous_variant 0.64 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.7 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.91 rifampicin
rpoC 766568 c.3199_3201delGTTinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766576 c.3207C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.88 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.88 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 0.94 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.95 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.94 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.85 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.85 rifampicin
rpoC 766633 c.3264G>C synonymous_variant 0.85 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.84 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.83 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.83 rifampicin
rpoC 766660 c.3291G>T synonymous_variant 0.83 rifampicin
rpoC 766661 p.Val1098Pro missense_variant 0.83 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.79 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.79 rifampicin Uncertain significance
rpoC 766690 c.3321G>C synonymous_variant 0.83 rifampicin
rpoC 766693 c.3324C>A synonymous_variant 0.78 rifampicin
rpoC 766702 c.3333G>C synonymous_variant 0.69 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.55 rifampicin
rpoC 766858 c.3489C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGA frameshift_variant&missense_variant 0.69 rifampicin
rpoC 766891 c.3522G>A synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.69 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.75 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.75 rifampicin
rpoC 766909 c.3540G>C synonymous_variant 0.82 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.82 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.82 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766920 p.Ala1184Gly missense_variant 0.9 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.85 rifampicin
rpoC 766935 p.Glu1189Ala missense_variant 0.85 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766961 p.Gly1198Asn missense_variant 0.87 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767080 c.3711G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767100 p.Lys1244Arg missense_variant 0.82 rifampicin
rpoC 767104 c.3735C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767107 c.3738C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Ser missense_variant 0.7 rifampicin Uncertain significance
rpoC 767188 c.3819G>A synonymous_variant 0.65 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.61 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.59 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767264 c.3895_3897delGCGinsTC frameshift_variant&missense_variant 0.58 rifampicin
rpoC 767267 p.Ala1300Asn missense_variant 0.58 rifampicin Uncertain significance
rpoC 767281 c.3912C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767302 c.3933C>A synonymous_variant 0.5 rifampicin
rpsL 781658 c.99A>G synonymous_variant 0.9 streptomycin
rpsL 781670 c.111G>C synonymous_variant 0.87 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.84 streptomycin
rpsL 781706 c.147T>G synonymous_variant 0.8 streptomycin
rpsL 781715 c.156T>G synonymous_variant 0.88 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.89 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 0.78 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.84 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.84 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.84 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 0.74 streptomycin
rpsL 781742 c.183C>G synonymous_variant 0.82 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.86 streptomycin
rpsL 781754 c.195G>T synonymous_variant 0.73 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.82 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.82 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.83 streptomycin Not assoc w R - Interim
rpsL 781784 c.225G>A synonymous_variant 0.77 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.72 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.75 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.75 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.72 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.72 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.68 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.65 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.65 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.65 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.65 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.71 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.71 streptomycin
rplC 800618 c.-191T>C upstream_gene_variant 0.8 linezolid
rplC 800639 c.-170C>T upstream_gene_variant 0.87 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.87 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.87 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.88 linezolid
rplC 800666 c.-143C>T upstream_gene_variant 0.83 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.83 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.71 linezolid
rplC 800703 c.-106_-104delTTGinsCC upstream_gene_variant 0.71 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.71 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.71 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.71 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.6 linezolid
rplC 800747 c.-62C>T upstream_gene_variant 0.53 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.5 linezolid
fbiC 1304619 c.1689G>T synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304660 p.Tyr577Phe missense_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304672 p.Val581Ala missense_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304684 p.Ala585Gly missense_variant 0.83 clofazimine Uncertain significance
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>T synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304784 c.1854T>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
atpE 1461107 c.63C>G synonymous_variant 0.9 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 0.93 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.94 bedaquiline
atpE 1461146 c.102G>C synonymous_variant 0.94 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.94 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.94 bedaquiline
atpE 1461161 c.117C>G synonymous_variant 0.94 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.94 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.94 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 0.94 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.88 bedaquiline
atpE 1461183 c.139_141delGGGinsAC frameshift_variant&missense_variant 0.88 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.85 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.9 bedaquiline
atpE 1461230 c.186G>T synonymous_variant 0.89 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.89 bedaquiline
atpE 1461242 c.198C>T synonymous_variant 0.88 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.82 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.82 bedaquiline
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472043 n.198T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472050 n.205G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472431 n.586G>A non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474074 n.417C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474103 n.446A>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474106 n.449_450insCT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474109 n.453_454delAT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474415 n.759_781delCACACGCGCATACGCGCGTGTGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.89 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
inhA 1673778 c.-424C>G upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673784 c.-418G>A upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673799 c.-403T>C upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1673808 c.-394A>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673816 p.Ser126Thr missense_variant 0.82 ethionamide
isoniazid
rpsA 1833540 c.-2_-1delATinsC upstream_gene_variant 0.73 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 0.79 pyrazinamide
rpsA 1833559 c.18C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.89 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.86 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.86 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833616 c.75A>T synonymous_variant 0.86 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.86 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.9 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.86 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.88 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.88 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833700 c.159C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.83 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833751 c.210C>T synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
rpsA 1833760 c.219C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.92 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.93 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.98 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.96 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.9 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.87 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.88 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.87 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.88 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.89 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834073 p.Lys178Arg missense_variant 0.87 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.86 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1834228 c.687C>A synonymous_variant 0.86 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.84 pyrazinamide
rpsA 1834234 c.693G>T synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.85 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.95 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 0.93 pyrazinamide
rpsA 1834405 c.864C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.91 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.9 pyrazinamide
rpsA 1834480 c.939C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.91 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834498 c.957C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.86 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.88 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.88 pyrazinamide
rpsA 1834557 p.Ala339Gly missense_variant 0.88 pyrazinamide
rpsA 1834564 c.1023C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834606 c.1065C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.81 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.76 pyrazinamide
rpsA 1834684 c.1143C>G synonymous_variant 0.73 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834700 p.Gln387Ala missense_variant 0.73 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.82 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.8 linezolid
tsnR 1853372 c.-234A>G upstream_gene_variant 0.8 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.8 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 0.8 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.8 linezolid
tsnR 1853390 c.-216G>T upstream_gene_variant 0.8 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.76 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.71 linezolid
tsnR 1853418 c.-188_-186delCTTinsTC upstream_gene_variant 0.71 linezolid
tsnR 1853429 c.-177G>T upstream_gene_variant 0.69 linezolid
kasA 2517917 c.-198G>C upstream_gene_variant 0.89 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.91 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.85 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.82 isoniazid
kasA 2518738 c.624G>C synonymous_variant 0.82 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.75 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.82 isoniazid
kasA 2518771 c.657C>A synonymous_variant 0.82 isoniazid
kasA 2518774 c.660C>T synonymous_variant 0.82 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.82 isoniazid
kasA 2518783 c.669T>G synonymous_variant 0.82 isoniazid
kasA 2518787 p.Arg225Lys missense_variant 0.82 isoniazid
kasA 2518792 c.678C>T synonymous_variant 0.75 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.69 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.64 isoniazid
kasA 2518807 c.693C>T synonymous_variant 0.64 isoniazid
kasA 2518822 c.708C>A synonymous_variant 0.64 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.69 isoniazid
kasA 2518849 c.735G>C synonymous_variant 0.69 isoniazid
kasA 2518853 p.Leu247Val missense_variant 0.64 isoniazid
thyA 3073950 c.522G>T synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073971 c.501C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073980 c.492C>T synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 0.89 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074010 c.462C>T synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074013 c.459C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074022 c.450C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.8 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.8 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074067 c.405C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.6 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
mtrB 3625687 c.927G>A synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625744 c.870G>A synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625753 c.859_861delGCCinsAT frameshift_variant&missense_variant 0.83 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625761 p.Gln285Glu missense_variant 0.83 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625768 c.-858G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625774 c.840G>A synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625792 c.822G>T synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625801 c.-891G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625807 c.-897C>A upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625819 p.Glu265Val missense_variant 0.87 bedaquiline
rifampicin Uncertain significance
lpqB 3625822 c.-912C>T upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrB 3626681 c.-68C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626717 c.-104C>T upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrA 3626756 c.594C>G synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626759 c.591T>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626762 c.588G>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626765 c.585C>T synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626776 c.-163A>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3627083 c.-470G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627133 p.Ala73Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627134 c.-521C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627149 c.-536G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627161 c.189C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627167 c.-554T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877542 c.966C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877545 c.963G>C synonymous_variant 0.93 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 0.94 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877596 c.912G>C synonymous_variant 0.96 rifampicin
rpoA 3877602 c.906C>T synonymous_variant 0.97 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.88 rifampicin
rpoA 3877665 c.843C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.88 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>T synonymous_variant 0.83 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.83 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.86 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.86 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.84 rifampicin
rpoA 3877758 c.750G>C synonymous_variant 0.83 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 0.83 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.84 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>T synonymous_variant 0.97 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877860 c.648C>T synonymous_variant 0.93 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 0.93 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.93 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 0.82 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 0.81 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.86 rifampicin
rpoA 3877974 c.534G>C synonymous_variant 0.79 rifampicin
rpoA 3877977 p.Lys177Asn missense_variant 0.82 rifampicin Uncertain significance
rpoA 3877983 c.525C>G synonymous_variant 0.83 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 0.79 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>C synonymous_variant 0.85 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.84 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.84 rifampicin
rpoA 3878028 c.480G>T synonymous_variant 0.84 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.84 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.85 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 0.88 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.88 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.9 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.9 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.86 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 0.88 rifampicin
rpoA 3878102 p.Val136Ile missense_variant 0.89 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.9 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.93 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.89 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.88 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.9 rifampicin Uncertain significance
rpoA 3878184 c.324C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>A synonymous_variant 0.78 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878274 c.234G>C synonymous_variant 0.76 rifampicin
rpoA 3878283 p.Glu75Asp missense_variant 0.75 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.74 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.7 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.7 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.7 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.7 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3878400 c.108T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
clpC1 4038725 c.1980C>T synonymous_variant 0.77 pyrazinamide
clpC1 4038737 c.1968C>T synonymous_variant 0.81 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.81 pyrazinamide
clpC1 4038743 c.1962G>A synonymous_variant 0.81 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>A synonymous_variant 0.95 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038770 c.1935C>A synonymous_variant 0.95 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.92 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.92 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038842 c.1863G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.94 pyrazinamide
clpC1 4038860 c.1845G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>A synonymous_variant 0.93 pyrazinamide
clpC1 4038884 c.1821C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.97 pyrazinamide
clpC1 4038896 c.1809C>A synonymous_variant 0.96 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.96 pyrazinamide
clpC1 4038914 c.1791G>T synonymous_variant 0.96 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038923 c.1782A>T synonymous_variant 0.96 pyrazinamide
clpC1 4038928 c.1777C>A synonymous_variant 0.96 pyrazinamide
clpC1 4038929 c.1776G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038932 c.1773G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039031 c.1674T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039077 p.Lys543Arg missense_variant 0.83 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4039082 c.1623C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.8 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.8 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.8 pyrazinamide
clpC1 4039100 c.1605C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039139 c.1566G>A synonymous_variant 0.85 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039145 c.1560G>T synonymous_variant 0.85 pyrazinamide
clpC1 4039166 c.1539G>A synonymous_variant 0.9 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.88 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.88 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039238 c.1467C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039280 c.1425G>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039283 c.1422C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 0.88 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039316 p.Glu463Asp missense_variant 0.77 pyrazinamide
clpC1 4039319 c.1386T>A synonymous_variant 0.77 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 0.77 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 0.77 pyrazinamide
clpC1 4039336 c.1369C>T synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4039338 p.Thr456Gln missense_variant 0.83 pyrazinamide
clpC1 4039346 p.Arg453Ser missense_variant 0.83 pyrazinamide
clpC1 4039360 p.Ser449Arg missense_variant 0.89 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.91 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.91 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039457 c.1248C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039553 c.1152C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.74 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.62 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039610 c.1095G>T synonymous_variant 0.84 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039649 c.1056G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039730 c.975C>T synonymous_variant 0.86 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039805 c.900C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039814 c.891C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.95 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039844 c.861C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039964 c.741C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039975 p.Asp244Asn missense_variant 0.83 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040000 c.705C>T synonymous_variant 0.75 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.71 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.69 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 0.68 pyrazinamide
clpC1 4040087 c.618G>T synonymous_variant 0.68 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.65 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040132 c.573C>T synonymous_variant 0.6 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.64 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.82 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040284 c.421C>T synonymous_variant 0.78 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.84 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.86 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040342 c.363C>T synonymous_variant 0.86 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040360 c.345G>A synonymous_variant 0.86 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.86 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.8 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040405 c.300C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040510 c.195G>A synonymous_variant 0.5 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.5 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040540 c.165G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040543 c.162C>T synonymous_variant 0.6 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 0.6 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.6 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.55 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.55 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.55 pyrazinamide
glpK 4138478 c.1278T>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138487 c.1267_1269delTTGinsCC frameshift_variant&missense_variant 0.46 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138495 p.Gln421Glu missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138500 p.Arg419His missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138508 c.1248C>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138514 c.1242A>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 c.1239A>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138526 p.Asp410Glu missense_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 p.Asp407Glu missense_variant 0.78 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138568 c.1188A>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138579 c.1177C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138580 c.1176C>T synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138589 c.1167C>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138604 c.1150_1152delTTGinsCT frameshift_variant&missense_variant 0.93 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138607 c.1149G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim