Run ID: SRR3675270
Sample name:
Date: 2024-10-04T23:42:32.528360
Number of reads: 235470
Percentage reads mapped: 20.05
Median coverage: 1.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| La1.2.BCG | M.bovis | None | 0.05 |
| lineage4 | Euro-American | None | 0.97 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.97 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| embB | 4247580 | p.Ala356Val | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 600 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 624 | c.624C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 747 | c.747G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 793 | p.Val265Ile | missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 798 | c.798C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 805 | c.805_807delTTGinsCTC | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 864 | c.864C>T | synonymous_variant | 1.0 | isoniazid | |
| gyrA | 7412 | c.111C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7421 | c.120G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7436 | c.135C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 0.93 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7613 | c.312G>A | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7673 | c.372G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7706 | c.405C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7758 | p.Ile153Val | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7778 | c.477G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7853 | c.552C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7886 | c.585T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7892 | c.591G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7898 | p.Asp199Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8309 | c.1008G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8408 | c.1107A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8438 | c.1137C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8649 | p.Arg450Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8705 | c.1404C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8717 | c.1416C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8723 | c.1422G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8731 | p.Gly477Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8740 | p.Arg480His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8761 | p.Val487Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8769 | p.His490Tyr | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8783 | c.1482G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8804 | c.1503C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8930 | c.1629C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9227 | c.1926C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| fgd1 | 491382 | c.600G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491478 | c.696G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491493 | c.711C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491523 | c.741G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491535 | c.753G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491563 | c.781_782delAGinsTC | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491595 | c.813C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| mshA | 575725 | c.378C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575751 | p.Gly135Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575761 | c.414C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| mshA | 575772 | p.Val142Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575795 | p.Ile150Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575840 | c.494dupC | frameshift_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 575844 | c.498delC | frameshift_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 575848 | c.501C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575851 | c.504C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734544 | c.291C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734614 | p.Ala121Ser | missense_variant | 0.92 | rifampicin | |
| nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734820 | c.567A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734826 | c.573A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734841 | c.588G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734859 | c.606G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734863 | p.Thr204Ser | missense_variant | 1.0 | rifampicin | |
| nusG | 734889 | c.636G>A | synonymous_variant | 0.88 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 0.88 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 0.85 | rifampicin | |
| nusG | 734922 | c.669C>T | synonymous_variant | 0.85 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760148 | p.Asp114Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760155 | p.Lys117Arg | missense_variant | 1.0 | rifampicin | |
| rpoB | 760172 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760178 | c.372G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760181 | c.375T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760199 | c.393C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760317 | c.511_512delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760337 | c.531C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760587 | p.Thr261Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760593 | p.Gly263Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 760596 | p.Thr264Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761201 | c.1395G>A | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761204 | c.1398C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761222 | c.1416G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761516 | c.1710G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761687 | c.1881C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761711 | c.1905C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 761723 | p.Glu639Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 761724 | p.Glu640Lys | missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | p.Ser641Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761789 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761814 | p.Ala670Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761847 | p.Cys681Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761868 | p.Asp688Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761897 | c.2091C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761903 | c.2097T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762006 | c.2200_2202delCGCinsAGG | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762024 | p.Val740Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762134 | c.2328C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762179 | c.2373C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762212 | c.2406G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762236 | c.2430G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762281 | c.2475G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762296 | c.2490G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762314 | c.2508C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762407 | c.-963G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762452 | c.2646G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoC | 762521 | c.-849C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762527 | c.-843G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762768 | p.Pro988Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762795 | p.Asp997Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762831 | c.3025_3026delAGinsTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762917 | c.3111C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763447 | c.78C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763465 | c.96G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763492 | c.123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763615 | c.246G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763618 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763705 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 763933 | c.564C>T | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoC | 763936 | c.567C>G | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 0.83 | rifampicin | Uncertain significance |
| rpoC | 763951 | c.582G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoC | 763972 | c.603C>T | synonymous_variant | 0.86 | rifampicin | |
| rpoC | 763987 | c.618C>T | synonymous_variant | 0.88 | rifampicin | |
| rpoC | 763991 | p.Ile208Leu | missense_variant | 0.88 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 0.88 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 764020 | c.651C>T | synonymous_variant | 0.87 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 0.87 | rifampicin | |
| rpoC | 764029 | p.Glu220Asp | missense_variant | 0.86 | rifampicin | |
| rpoC | 764030 | p.Asp221Asn | missense_variant | 0.86 | rifampicin | Uncertain significance |
| rpoC | 764039 | p.Ser224Asp | missense_variant | 0.92 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764048 | p.Thr227Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764085 | p.Asn239Thr | missense_variant | 0.92 | rifampicin | Uncertain significance |
| rpoC | 764087 | p.Leu240Val | missense_variant | 0.92 | rifampicin | Uncertain significance |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764134 | c.765C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764207 | p.Val280Thr | missense_variant | 0.94 | rifampicin | Uncertain significance |
| rpoC | 764213 | p.Arg282Lys | missense_variant | 0.89 | rifampicin | Uncertain significance |
| rpoC | 764242 | c.873C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764287 | c.918C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764293 | c.924G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764317 | c.948C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764341 | c.972G>T | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764347 | c.978G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764410 | c.1041G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764429 | c.1060C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066_1068delAGGinsCGA | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764489 | c.1120C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764548 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764605 | c.1236G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764611 | c.1242G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764809 | c.1440C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764863 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764908 | c.1539G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764971 | c.1602C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764983 | c.1614T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765076 | c.1707A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765104 | c.1735C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765445 | c.2076G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765453 | p.Ala695Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765508 | c.2139C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765547 | c.2178C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765619 | c.2250G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765662 | c.2293_2295delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765718 | p.Asp783Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765724 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765730 | c.2361G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765742 | p.Glu791Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766043 | p.Gln892Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766291 | c.2922G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766309 | c.2940G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766312 | c.2943T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766315 | c.2946C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766366 | c.2997C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766459 | c.3090G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766468 | c.3099G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | p.Val1039Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766517 | p.Thr1050Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766537 | c.3168G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766547 | p.Arg1060Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766576 | c.3207C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766582 | c.3213C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766610 | p.Ser1081Pro | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766661 | p.Val1098Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766667 | p.Ser1100Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766696 | c.3327G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766702 | c.3333G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766708 | c.3339A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766787 | p.Glu1140Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766888 | c.3519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766911 | p.Ile1181Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766915 | p.Asp1182Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766931 | p.Ala1188Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766942 | c.3573C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766978 | c.3609C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | p.Asn1246Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781664 | c.105C>T | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781772 | c.213C>T | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781829 | c.270G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800700 | c.-109C>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800714 | c.-95C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801210 | c.402T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801220 | p.Ser138Gly | missense_variant | 1.0 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>G | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303464 | c.534A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303492 | c.562T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303500 | c.570C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303512 | c.582T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303536 | c.606G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303581 | c.651G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303584 | c.654C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304751 | c.1821C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304760 | c.1830G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304769 | c.1839C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304772 | c.1842C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304790 | c.1860C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304826 | c.1896G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304832 | c.1902C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304845 | p.Ala639Thr | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304853 | c.1923C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304857 | p.Thr643Ser | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304868 | c.1938G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304880 | c.1950C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| sigE | 1364901 | c.489C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364913 | c.501C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364926 | p.Asn172Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364960 | p.Gly183Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364964 | c.552T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364976 | c.564T>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364979 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364989 | c.577C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364992 | p.Pro194Ala | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1365003 | c.591T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365006 | c.594T>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365009 | c.597C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365012 | c.600G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365024 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471926 | n.81C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471985 | n.140T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472017 | n.172C>T | non_coding_transcript_exon_variant | 0.6 | kanamycin | |
| capreomycin | ||||||
| streptomycin | Uncertain significance | |||||
| amikacin | ||||||
| rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.9 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473111 | n.1266A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.96 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445delCinsTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.8 | capreomycin | |
| linezolid | ||||||
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| inhA | 1673799 | c.-403T>C | upstream_gene_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673805 | c.-397G>C | upstream_gene_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673808 | c.-394A>C | upstream_gene_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673811 | c.-391G>A | upstream_gene_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673901 | c.-301A>G | upstream_gene_variant | 0.91 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674789 | c.588G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674830 | p.Glu210Gly | missense_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674837 | c.636C>T | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674839 | p.Ala213Glu | missense_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674848 | p.Gln216Arg | missense_variant | 0.94 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674883 | p.Ile228Val | missense_variant | 0.95 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1674892 | p.Asn231Asp | missense_variant | 0.95 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1674900 | c.699G>A | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674909 | c.708G>C | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674915 | c.714C>G | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674927 | c.726G>C | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674933 | c.732G>A | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674942 | c.741T>G | synonymous_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833616 | c.75A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833730 | c.189C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833769 | c.228C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833770 | p.Asn77His | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833778 | c.237C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833781 | c.240T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833814 | c.273C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833886 | c.345C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833892 | c.351G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.96 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834040 | p.Lys167Arg | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834051 | c.510G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | p.Asn205Gln | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834172 | p.Ile211Val | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834432 | c.891G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834527 | p.Arg329Gln | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834558 | c.1017C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834603 | p.Glu354Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834666 | c.1125G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834684 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834747 | c.1206A>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834751 | p.Leu404Ile | missense_variant | 0.96 | pyrazinamide | |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.96 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsACC | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853417 | c.-189G>C | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853444 | c.-162C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853474 | c.-132C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853480 | c.-126G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853481 | c.-125A>G | upstream_gene_variant | 1.0 | linezolid | |
| kasA | 2517926 | c.-189G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517956 | c.-159G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517965 | c.-150C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518579 | c.465T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518585 | c.471G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518594 | c.480C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518606 | c.492G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518636 | c.522C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518688 | p.Val192Phe | missense_variant | 1.0 | isoniazid | |
| kasA | 2518693 | c.579C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518715 | p.Pro201Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2518726 | c.612G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518756 | c.642G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518759 | c.645C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518780 | p.Glu222Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518787 | p.Arg225Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518811 | p.Asp233Asn | missense_variant | 1.0 | isoniazid | |
| kasA | 2518816 | c.702C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518834 | c.720C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>C | synonymous_variant | 1.0 | isoniazid | |
| Rv2477c | 2782447 | c.1596C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782453 | c.1590C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782491 | p.Asn518Asp | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782496 | p.Asp516Ala | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782510 | c.1533G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782537 | c.1506T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782555 | c.1488G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782558 | c.1485T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782567 | c.1476C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782576 | c.1467C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782582 | c.1461C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.82 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783329 | c.714G>A | synonymous_variant | 0.85 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.85 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783335 | c.708C>T | synonymous_variant | 0.85 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783344 | c.699C>G | synonymous_variant | 0.87 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.9 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783373 | p.Glu224Gln | missense_variant | 0.91 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>C | synonymous_variant | 0.93 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783443 | p.Gln200Ala | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783485 | c.558G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783509 | c.534C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783926 | c.117C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783935 | c.108C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073950 | c.522G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625135 | c.1479A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625138 | c.-228C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625255 | c.-345T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625263 | p.Tyr451His | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625301 | p.Ala438Gly | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625313 | p.Arg434Val | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625321 | c.1293A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625351 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625572 | p.Thr348Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625585 | c.-675G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625591 | c.-681C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625599 | p.Met339Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625623 | p.Thr331Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625627 | p.Asp329Glu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625636 | p.Ala326Glu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625648 | p.Tyr322His | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625657 | c.-747C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625720 | c.-810G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625732 | c.882C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3625762 | c.852A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625804 | c.-896_-894delAGGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625807 | c.807C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625852 | c.-942A>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625882 | c.-972G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626756 | c.-143C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626776 | c.-163A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626804 | c.-191A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626822 | p.Asp176Glu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626843 | c.-230G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626858 | c.-245A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626881 | c.-268C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626915 | c.-302C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626942 | p.Val136Ile | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626995 | c.-382C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626999 | c.-386G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627026 | c.324G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrA | 3627056 | c.294C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627068 | c.282T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627188 | c.-577_-575delTTAinsCTG | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627191 | c.-578G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627213 | p.Arg46His | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627224 | c.-611G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627227 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627247 | p.Ile35Val | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627275 | c.-662G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| rpoA | 3877514 | p.Thr332Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877524 | c.984C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877548 | c.960C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877569 | p.Pro313Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877575 | c.933C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877581 | c.927G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877593 | c.915C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877611 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877629 | c.879C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877662 | c.846C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877674 | c.834C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | c.831G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877689 | c.819C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877695 | c.813C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3877710 | c.798C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877731 | c.777G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877785 | c.723C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877788 | c.720G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877881 | c.627G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877893 | c.615C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877905 | c.603A>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877929 | p.Ile193Val | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877974 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878145 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878175 | c.333G>T | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878196 | p.Glu104Ala | missense_variant | 0.89 | rifampicin | Uncertain significance |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3878253 | c.255G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878262 | p.Ser82Gly | missense_variant | 0.96 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878276 | c.232C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.94 | rifampicin | Uncertain significance |
| rpoA | 3878295 | c.213A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878304 | c.204G>T | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878394 | c.114G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878403 | c.105C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 0.83 | rifampicin | |
| rpoA | 3878725 | c.-218A>T | upstream_gene_variant | 0.91 | rifampicin | |
| rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.91 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.83 | rifampicin | Uncertain significance |
| rpoA | 3878758 | c.-251G>C | upstream_gene_variant | 0.86 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.86 | rifampicin | |
| rpoA | 3878775 | c.-268A>G | upstream_gene_variant | 0.86 | rifampicin | Uncertain significance |
| rpoA | 3878779 | c.-272C>T | upstream_gene_variant | 0.86 | rifampicin | Uncertain significance |
| rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 0.88 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.88 | rifampicin | Uncertain significance |
| rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 0.88 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.87 | rifampicin | |
| rpoA | 3878830 | c.-325_-323delCTGinsATC | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878843 | c.-337_-336delCGinsAA | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878845 | c.-338G>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878873 | c.-366G>A | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.92 | rifampicin | Uncertain significance |
| rpoA | 3878947 | c.-440G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 1.0 | rifampicin | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.82 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>G | synonymous_variant | 0.83 | pyrazinamide | |
| clpC1 | 4038650 | c.2055C>T | synonymous_variant | 0.82 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038679 | p.Pro676Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038698 | c.2007C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038726 | p.Thr660Cys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038779 | c.1926C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038794 | c.1909_1911delAGCinsTCG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038875 | c.1830C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038905 | c.1800A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038986 | c.1719C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038995 | c.1708_1710delTTGinsCTC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039001 | p.Asn568Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039016 | c.1689C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039070 | c.1635G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039073 | c.1632C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039124 | c.1581C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039127 | p.Lys526Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039141 | p.Glu522Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039187 | c.1518G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039223 | c.1482C>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039271 | c.1434G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039313 | c.1392C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039328 | c.1377A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039501 | c.1204C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039522 | c.1183C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039532 | c.1173C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>A | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039568 | p.Met379Ile | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039576 | p.Ala377Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039581 | p.Thr375Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039601 | c.1104G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039655 | c.1050G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039736 | c.969C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039754 | c.951G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039802 | c.903G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039805 | c.900C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039855 | c.850C>T | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039871 | c.834C>T | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039925 | c.780C>T | synonymous_variant | 0.94 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>A | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040001 | p.His235Ala | missense_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040009 | c.696C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040027 | c.678C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040057 | c.648C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040126 | c.579C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040135 | c.570C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040144 | c.561G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040168 | c.537G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040180 | c.525C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040200 | c.505T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040204 | c.501G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040213 | c.492T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040234 | c.471C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040252 | c.453C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040257 | p.Ala150Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040276 | c.427_429delTCCinsAGT | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040303 | c.402G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040315 | p.Glu130Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040330 | c.375C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040468 | c.237G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040513 | c.192G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040531 | c.174T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040540 | c.165G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040600 | c.103_105delTTAinsCTC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040618 | c.87C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040645 | c.60C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040660 | c.45G>C | synonymous_variant | 1.0 | pyrazinamide | |
| glpK | 4138547 | c.1209C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138550 | c.1206C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138568 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138598 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138601 | c.1155G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138622 | c.1134C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138634 | c.1122G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241008 | c.1146G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 0.92 | ethambutol | |
| embC | 4241024 | p.Val388Phe | missense_variant | 1.0 | ethambutol | |
| embC | 4241036 | c.1174C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241053 | c.1191G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241084 | p.Leu408Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4241135 | p.Val425Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241197 | c.1335G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241578 | c.1716G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241584 | c.1722T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241587 | c.1725C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241591 | p.Leu577Ile | missense_variant | 1.0 | ethambutol | |
| embC | 4241608 | c.1746C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241611 | c.1749G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241614 | c.1752A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241623 | c.1761C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241644 | c.1782G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241648 | c.1786T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241659 | c.1797G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241665 | c.1803G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241671 | c.1809T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241677 | c.1815G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4242919 | c.-314A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242922 | c.-311C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242928 | c.3066A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244801 | c.1569G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244802 | c.1570T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244814 | p.Leu528Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244821 | p.Gly530Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4244823 | p.Val531Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244829 | p.Phe533Val | missense_variant | 1.0 | ethambutol | |
| embA | 4244849 | c.1617C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244853 | p.Val541Ile | missense_variant | 1.0 | ethambutol | |
| embA | 4244856 | p.Ala542Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4244862 | p.Leu544Val | missense_variant | 1.0 | ethambutol | |
| embA | 4244885 | c.1653A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244894 | c.1662C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244895 | p.Thr555Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4244900 | c.1668G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244906 | c.1674C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244919 | c.1687_1689delCTCinsTTG | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244930 | c.1698G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247536 | c.1023C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247543 | c.1030_1031delAGinsTC | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247555 | p.Leu348Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247563 | p.Met350Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247567 | c.1054C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247576 | c.1063C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248052 | c.1539G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248055 | c.1542G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248064 | c.1551G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248139 | c.1626C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248173 | p.Val554Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248190 | c.1677G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248202 | c.1689T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248203 | p.Pro564Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248215 | p.Arg568Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248225 | p.Ala571Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248244 | c.1731C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248248 | p.Phe579Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4248252 | p.Gly580Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248256 | c.1743C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248264 | p.Phe584Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248275 | p.Thr588Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248298 | c.1785C>T | synonymous_variant | 1.0 | ethambutol |
