TB-Profiler

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	0.91
lineage4.9	Euro-American (H37Rv-like)	None	0.89

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rrs	1472307	n.462C>T	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance	Mutation from literature
embB	4247448	p.His312Arg	missense_variant	1.0	ethambutol		Mutation from literature
embB	4247588	p.Leu359Ile	missense_variant	1.0	ethambutol	Uncertain significance	Mutation from literature
embB	4247676	p.Ala388Gly	missense_variant	0.85	ethambutol		Mutation from literature
embB	4247708	p.Asn399Asp	missense_variant	0.89	ethambutol		Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
dnaA	909	c.909A>C	synonymous_variant	0.8	isoniazid	Not assoc w R - Interim
dnaA	912	c.912T>G	synonymous_variant	0.8	isoniazid
dnaA	918	c.918C>G	synonymous_variant	0.8	isoniazid
dnaA	921	c.921A>G	synonymous_variant	0.8	isoniazid	Not assoc w R - Interim
dnaA	969	c.969G>A	synonymous_variant	0.7	isoniazid
dnaA	975	c.975G>T	synonymous_variant	0.7	isoniazid
dnaA	993	c.993A>G	synonymous_variant	0.7	isoniazid
dnaA	996	c.996A>C	synonymous_variant	0.7	isoniazid	Not assoc w R - Interim
dnaA	999	c.999C>G	synonymous_variant	0.7	isoniazid
dnaA	1092	c.1092T>C	synonymous_variant	0.73	isoniazid	Not assoc w R - Interim
dnaA	1098	c.1098A>G	synonymous_variant	0.76	isoniazid
dnaA	1104	c.1104T>C	synonymous_variant	0.76	isoniazid
dnaA	1110	c.1110T>C	synonymous_variant	0.76	isoniazid
dnaA	1113	c.1113A>G	synonymous_variant	0.76	isoniazid
dnaA	1125	c.1125G>C	synonymous_variant	0.85	isoniazid
dnaA	1137	c.1137C>G	synonymous_variant	0.88	isoniazid
dnaA	1143	c.1143G>C	synonymous_variant	0.92	isoniazid
dnaA	1152	c.1152A>G	synonymous_variant	0.96	isoniazid
dnaA	1153	c.1153T>C	synonymous_variant	0.96	isoniazid
dnaA	1161	c.1161A>G	synonymous_variant	0.96	isoniazid
dnaA	1164	c.1164A>C	synonymous_variant	0.96	isoniazid
dnaA	1167	c.1167A>G	synonymous_variant	0.96	isoniazid	Not assoc w R - Interim
dnaA	1176	c.1176A>G	synonymous_variant	0.96	isoniazid
dnaA	1188	c.1188G>A	synonymous_variant	0.96	isoniazid
dnaA	1191	c.1191T>C	synonymous_variant	0.96	isoniazid
dnaA	1197	c.1197T>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	1204	c.1204C>T	synonymous_variant	1.0	isoniazid
dnaA	1220	p.Asn407Ser	missense_variant	1.0	isoniazid
dnaA	1230	c.1230A>G	synonymous_variant	1.0	isoniazid
gyrB	6123	p.Ala295Gly	missense_variant	0.8	levofloxacin
gyrB	6123	p.Ala295Gly	missense_variant	0.8	moxifloxacin
gyrB	6127	c.888G>C	synonymous_variant	0.8	levofloxacin
gyrB	6127	c.888G>C	synonymous_variant	0.8	moxifloxacin
gyrB	6130	c.891T>C	synonymous_variant	0.91	levofloxacin
gyrB	6130	c.891T>C	synonymous_variant	0.91	moxifloxacin
gyrB	6136	c.897G>A	synonymous_variant	0.83	levofloxacin	Not assoc w R - Interim
gyrB	6136	c.897G>A	synonymous_variant	0.83	moxifloxacin
gyrB	6139	c.900G>C	synonymous_variant	0.85	levofloxacin
gyrB	6139	c.900G>C	synonymous_variant	0.85	moxifloxacin
gyrB	6238	c.999G>A	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrB	6242	p.Arg335Lys	missense_variant	0.91	levofloxacin
gyrB	6242	p.Arg335Lys	missense_variant	0.91	moxifloxacin
gyrB	6250	c.1011A>G	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrB	6250	c.1011A>G	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrB	6256	c.1017G>A	synonymous_variant	0.93	levofloxacin
gyrB	6256	c.1017G>A	synonymous_variant	0.93	moxifloxacin
gyrB	6268	c.1029C>G	synonymous_variant	0.98	levofloxacin
gyrB	6268	c.1029C>G	synonymous_variant	0.98	moxifloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.95	levofloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.95	moxifloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.95	levofloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.95	moxifloxacin
gyrB	6289	c.1050C>T	synonymous_variant	0.95	levofloxacin
gyrB	6289	c.1050C>T	synonymous_variant	0.95	moxifloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.95	levofloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.95	moxifloxacin
gyrB	6307	c.1068T>G	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrB	6307	c.1068T>G	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrB	6319	c.1080G>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrB	6319	c.1080G>C	synonymous_variant	0.94	moxifloxacin
gyrA	6362	c.-940T>C	upstream_gene_variant	0.86	levofloxacin
gyrA	6362	c.-940T>C	upstream_gene_variant	0.86	moxifloxacin
gyrA	6376	c.-926G>A	upstream_gene_variant	0.87	levofloxacin
gyrA	6376	c.-926G>A	upstream_gene_variant	0.87	moxifloxacin
gyrA	6379	c.-923C>G	upstream_gene_variant	0.86	levofloxacin
gyrA	6379	c.-923C>G	upstream_gene_variant	0.86	moxifloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	0.86	levofloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	0.86	moxifloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	0.86	levofloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	0.86	moxifloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	0.82	levofloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	0.82	moxifloxacin
gyrA	6415	c.-887G>C	upstream_gene_variant	0.77	levofloxacin
gyrA	6415	c.-887G>C	upstream_gene_variant	0.77	moxifloxacin
gyrA	6598	c.-704C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6598	c.-704C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6610	c.-692C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6610	c.-692C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	1.0	levofloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	1.0	moxifloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6637	c.-665T>A	upstream_gene_variant	1.0	levofloxacin
gyrA	6637	c.-665T>A	upstream_gene_variant	1.0	moxifloxacin
gyrA	6640	c.-662A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6640	c.-662A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6646	c.-656C>T	upstream_gene_variant	1.0	levofloxacin
gyrA	6646	c.-656C>T	upstream_gene_variant	1.0	moxifloxacin
gyrA	6649	c.-653T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6649	c.-653T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6670	c.-632G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6670	c.-632G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6680	c.1441C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6680	c.1441C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6700	c.-602T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6700	c.-602T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6712	c.-590G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6712	c.-590G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6728	c.-574_-572delCTAinsTTG	upstream_gene_variant	1.0	levofloxacin
gyrA	6728	c.-574_-572delCTAinsTTG	upstream_gene_variant	1.0	moxifloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6745	c.1506T>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6745	c.1506T>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	6751	c.-551G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6751	c.-551G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6763	c.1524G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6763	c.1524G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6775	c.1536G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6775	c.1536G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6797	p.Gly520Thr	missense_variant	1.0	levofloxacin
gyrB	6797	p.Gly520Thr	missense_variant	1.0	moxifloxacin
gyrA	7763	c.462T>C	synonymous_variant	0.87	levofloxacin	Not assoc w R - Interim
gyrA	7763	c.462T>C	synonymous_variant	0.87	moxifloxacin	Not assoc w R - Interim
gyrA	7775	c.474C>A	synonymous_variant	0.81	levofloxacin
gyrA	7775	c.474C>A	synonymous_variant	0.81	moxifloxacin
gyrA	7781	c.480G>C	synonymous_variant	0.81	levofloxacin
gyrA	7781	c.480G>C	synonymous_variant	0.81	moxifloxacin
gyrA	7784	c.483A>G	synonymous_variant	0.81	levofloxacin
gyrA	7784	c.483A>G	synonymous_variant	0.81	moxifloxacin
gyrA	7790	c.489G>C	synonymous_variant	0.81	levofloxacin
gyrA	7790	c.489G>C	synonymous_variant	0.81	moxifloxacin
gyrA	7793	c.492G>C	synonymous_variant	0.81	levofloxacin
gyrA	7793	c.492G>C	synonymous_variant	0.81	moxifloxacin
gyrA	7796	c.495G>C	synonymous_variant	0.81	levofloxacin
gyrA	7796	c.495G>C	synonymous_variant	0.81	moxifloxacin
gyrA	7799	c.498A>G	synonymous_variant	0.81	levofloxacin	Not assoc w R - Interim
gyrA	7799	c.498A>G	synonymous_variant	0.81	moxifloxacin	Not assoc w R - Interim
gyrA	7814	c.513C>G	synonymous_variant	0.81	levofloxacin	Not assoc w R - Interim
gyrA	7814	c.513C>G	synonymous_variant	0.81	moxifloxacin	Not assoc w R - Interim
gyrA	7823	c.522G>C	synonymous_variant	0.81	levofloxacin
gyrA	7823	c.522G>C	synonymous_variant	0.81	moxifloxacin
gyrA	7832	c.531G>T	synonymous_variant	0.79	levofloxacin
gyrA	7832	c.531G>T	synonymous_variant	0.79	moxifloxacin
gyrA	7835	c.534A>C	synonymous_variant	0.85	levofloxacin
gyrA	7835	c.534A>C	synonymous_variant	0.85	moxifloxacin
gyrA	7853	c.552C>G	synonymous_variant	0.85	levofloxacin
gyrA	7853	c.552C>G	synonymous_variant	0.85	moxifloxacin
gyrA	7859	c.558A>G	synonymous_variant	0.79	levofloxacin
gyrA	7859	c.558A>G	synonymous_variant	0.79	moxifloxacin
gyrA	8069	c.768T>C	synonymous_variant	0.92	levofloxacin
gyrA	8069	c.768T>C	synonymous_variant	0.92	moxifloxacin
gyrA	8078	c.777A>G	synonymous_variant	1.0	levofloxacin
gyrA	8078	c.777A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8090	c.789C>A	synonymous_variant	1.0	levofloxacin
gyrA	8090	c.789C>A	synonymous_variant	1.0	moxifloxacin
gyrA	8093	c.792C>T	synonymous_variant	1.0	levofloxacin
gyrA	8093	c.792C>T	synonymous_variant	1.0	moxifloxacin
gyrA	8096	c.795T>A	synonymous_variant	1.0	levofloxacin
gyrA	8096	c.795T>A	synonymous_variant	1.0	moxifloxacin
gyrA	8099	c.798T>C	synonymous_variant	1.0	levofloxacin
gyrA	8099	c.798T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8111	c.810G>C	synonymous_variant	1.0	levofloxacin
gyrA	8111	c.810G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8121	c.820T>C	synonymous_variant	1.0	levofloxacin
gyrA	8121	c.820T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8129	c.828T>C	synonymous_variant	1.0	levofloxacin
gyrA	8129	c.828T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8135	c.834C>G	synonymous_variant	1.0	levofloxacin
gyrA	8135	c.834C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8156	c.855T>C	synonymous_variant	1.0	levofloxacin
gyrA	8156	c.855T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8168	c.867A>G	synonymous_variant	1.0	levofloxacin
gyrA	8168	c.867A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8172	p.Val291Ile	missense_variant	1.0	levofloxacin
gyrA	8172	p.Val291Ile	missense_variant	1.0	moxifloxacin
gyrA	8177	c.876A>C	synonymous_variant	1.0	levofloxacin
gyrA	8177	c.876A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8198	c.897T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8198	c.897T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8207	c.906T>C	synonymous_variant	0.97	levofloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8219	c.918T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8219	c.918T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8225	c.924T>C	synonymous_variant	0.97	levofloxacin
gyrA	8225	c.924T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8234	c.933T>C	synonymous_variant	0.96	levofloxacin
gyrA	8234	c.933T>C	synonymous_variant	0.96	moxifloxacin
gyrA	8237	c.936A>G	synonymous_variant	0.96	levofloxacin
gyrA	8237	c.936A>G	synonymous_variant	0.96	moxifloxacin
gyrA	8247	p.Ile316Val	missense_variant	0.96	levofloxacin
gyrA	8247	p.Ile316Val	missense_variant	0.96	moxifloxacin
gyrA	8264	c.963T>C	synonymous_variant	0.93	levofloxacin
gyrA	8264	c.963T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8267	c.966G>C	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	8267	c.966G>C	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	8270	c.969G>C	synonymous_variant	0.93	levofloxacin
gyrA	8270	c.969G>C	synonymous_variant	0.93	moxifloxacin
gyrA	8276	c.975G>A	synonymous_variant	0.93	levofloxacin
gyrA	8276	c.975G>A	synonymous_variant	0.93	moxifloxacin
gyrA	8283	p.Ile328Leu	missense_variant	0.92	levofloxacin	Uncertain significance
gyrA	8283	p.Ile328Leu	missense_variant	0.92	moxifloxacin	Uncertain significance
gyrA	8288	c.987T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	8288	c.987T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8324	c.1023T>C	synonymous_variant	0.9	levofloxacin
gyrA	8324	c.1023T>C	synonymous_variant	0.9	moxifloxacin
gyrA	8330	c.1029C>G	synonymous_variant	0.88	levofloxacin	Not assoc w R - Interim
gyrA	8330	c.1029C>G	synonymous_variant	0.88	moxifloxacin	Not assoc w R - Interim
gyrA	8339	c.1038A>G	synonymous_variant	0.88	levofloxacin
gyrA	8339	c.1038A>G	synonymous_variant	0.88	moxifloxacin
gyrA	8340	p.Ala347Ser	missense_variant	0.92	levofloxacin	Uncertain significance
gyrA	8340	p.Ala347Ser	missense_variant	0.92	moxifloxacin	Uncertain significance
gyrA	8372	c.1071G>C	synonymous_variant	0.89	levofloxacin
gyrA	8372	c.1071G>C	synonymous_variant	0.89	moxifloxacin
gyrA	8375	c.1074G>C	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrA	8375	c.1074G>C	synonymous_variant	0.89	moxifloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.88	levofloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.88	moxifloxacin
gyrA	8387	c.1086C>T	synonymous_variant	0.85	levofloxacin	Not assoc w R - Interim
gyrA	8387	c.1086C>T	synonymous_variant	0.85	moxifloxacin	Not assoc w R - Interim
gyrA	8391	p.Tyr364His	missense_variant	0.88	levofloxacin
gyrA	8391	p.Tyr364His	missense_variant	0.88	moxifloxacin
gyrA	8399	c.1098T>G	synonymous_variant	0.91	levofloxacin
gyrA	8399	c.1098T>G	synonymous_variant	0.91	moxifloxacin
gyrA	8401	p.Asp367Ala	missense_variant	0.91	levofloxacin
gyrA	8401	p.Asp367Ala	missense_variant	0.91	moxifloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.92	levofloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.92	moxifloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.93	levofloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8442	c.1141C>T	synonymous_variant	0.94	levofloxacin
gyrA	8442	c.1141C>T	synonymous_variant	0.94	moxifloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.92	levofloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.92	moxifloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.91	levofloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.91	moxifloxacin
gyrA	8462	c.1161A>T	synonymous_variant	0.91	levofloxacin
gyrA	8462	c.1161A>T	synonymous_variant	0.91	moxifloxacin
gyrA	8465	c.1164C>G	synonymous_variant	0.95	levofloxacin
gyrA	8465	c.1164C>G	synonymous_variant	0.95	moxifloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.95	levofloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.95	moxifloxacin
gyrA	8472	c.1171C>T	synonymous_variant	0.95	levofloxacin
gyrA	8472	c.1171C>T	synonymous_variant	0.95	moxifloxacin
gyrA	8480	c.1179C>A	synonymous_variant	0.95	levofloxacin
gyrA	8480	c.1179C>A	synonymous_variant	0.95	moxifloxacin
gyrA	8486	c.1185T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8486	c.1185T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8504	c.1203G>C	synonymous_variant	0.85	levofloxacin
gyrA	8504	c.1203G>C	synonymous_variant	0.85	moxifloxacin
gyrA	8516	c.1215T>C	synonymous_variant	0.93	levofloxacin
gyrA	8516	c.1215T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8519	c.1218A>C	synonymous_variant	1.0	levofloxacin
gyrA	8519	c.1218A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8520	c.1219C>T	synonymous_variant	1.0	levofloxacin
gyrA	8520	c.1219C>T	synonymous_variant	1.0	moxifloxacin
gyrA	8528	c.1227G>C	synonymous_variant	1.0	levofloxacin
gyrA	8528	c.1227G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8543	c.1242C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8543	c.1242C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8552	c.1251C>A	synonymous_variant	1.0	levofloxacin
gyrA	8552	c.1251C>A	synonymous_variant	1.0	moxifloxacin
gyrA	8561	c.1260A>G	synonymous_variant	1.0	levofloxacin
gyrA	8561	c.1260A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8576	c.1275C>G	synonymous_variant	1.0	levofloxacin
gyrA	8576	c.1275C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8579	c.1278C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8579	c.1278C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8588	c.1287G>A	synonymous_variant	1.0	levofloxacin
gyrA	8588	c.1287G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8597	c.1296C>G	synonymous_variant	1.0	levofloxacin
gyrA	8597	c.1296C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8603	c.1302A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8603	c.1302A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8619	c.1318_1320delTTGinsCTA	synonymous_variant	1.0	levofloxacin
gyrA	8619	c.1318_1320delTTGinsCTA	synonymous_variant	1.0	moxifloxacin
gyrA	8624	c.1323G>C	synonymous_variant	1.0	levofloxacin
gyrA	8624	c.1323G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8636	c.1335A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8636	c.1335A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8642	c.1341A>G	synonymous_variant	1.0	levofloxacin
gyrA	8642	c.1341A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8678	c.1377G>A	synonymous_variant	1.0	levofloxacin
gyrA	8678	c.1377G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8693	c.1392T>C	synonymous_variant	1.0	levofloxacin
gyrA	8693	c.1392T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8696	c.1395G>C	synonymous_variant	1.0	levofloxacin
gyrA	8696	c.1395G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8699	c.1398A>G	synonymous_variant	1.0	levofloxacin
gyrA	8699	c.1398A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8711	c.1410A>C	synonymous_variant	1.0	levofloxacin
gyrA	8711	c.1410A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8714	c.1413A>G	synonymous_variant	1.0	levofloxacin
gyrA	8714	c.1413A>G	synonymous_variant	1.0	moxifloxacin
gyrA	8729	c.1428T>C	synonymous_variant	1.0	levofloxacin
gyrA	8729	c.1428T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8730	p.Gly477Arg	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	8730	p.Gly477Arg	missense_variant	1.0	moxifloxacin
gyrA	8740	p.Arg480His	missense_variant	1.0	levofloxacin
gyrA	8740	p.Arg480His	missense_variant	1.0	moxifloxacin
gyrA	8828	c.1527T>C	synonymous_variant	1.0	levofloxacin
gyrA	8828	c.1527T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8837	c.1536C>T	synonymous_variant	1.0	levofloxacin
gyrA	8837	c.1536C>T	synonymous_variant	1.0	moxifloxacin
gyrA	8852	c.1551T>C	synonymous_variant	1.0	levofloxacin
gyrA	8852	c.1551T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8858	c.1557T>C	synonymous_variant	1.0	levofloxacin
gyrA	8858	c.1557T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8867	c.1566A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8867	c.1566A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8891	c.1590G>A	synonymous_variant	1.0	levofloxacin
gyrA	8891	c.1590G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8897	c.1596T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8933	c.1632G>C	synonymous_variant	1.0	levofloxacin
gyrA	8933	c.1632G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8939	c.1638T>C	synonymous_variant	1.0	levofloxacin
gyrA	8939	c.1638T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8942	c.1641G>C	synonymous_variant	1.0	levofloxacin
gyrA	8942	c.1641G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8946	c.1645_1647delTTGinsCTC	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8946	c.1645_1647delTTGinsCTC	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8966	c.1665C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8966	c.1665C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8967	p.Ala556Arg	missense_variant	1.0	levofloxacin
gyrA	8967	p.Ala556Arg	missense_variant	1.0	moxifloxacin
gyrA	8987	c.1686C>G	synonymous_variant	1.0	levofloxacin
gyrA	8987	c.1686C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8990	c.1689C>G	synonymous_variant	1.0	levofloxacin
gyrA	8990	c.1689C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8996	c.1695T>C	synonymous_variant	1.0	levofloxacin
gyrA	8996	c.1695T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8998	p.Leu566Trp	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	8998	p.Leu566Trp	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	9017	c.1716C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9017	c.1716C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9089	c.1788G>C	synonymous_variant	1.0	levofloxacin
gyrA	9089	c.1788G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9099	c.1798_1800delTTAinsCTG	synonymous_variant	0.93	levofloxacin
gyrA	9099	c.1798_1800delTTAinsCTG	synonymous_variant	0.93	moxifloxacin
gyrA	9104	c.1803C>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	9104	c.1803C>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	9119	c.1818A>G	synonymous_variant	0.94	levofloxacin
gyrA	9119	c.1818A>G	synonymous_variant	0.94	moxifloxacin
gyrA	9122	c.1821C>G	synonymous_variant	0.89	levofloxacin	Not assoc w R - Interim
gyrA	9122	c.1821C>G	synonymous_variant	0.89	moxifloxacin	Not assoc w R - Interim
gyrA	9143	c.1842T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R
gyrA	9143	c.1842T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R
gyrA	9152	c.1851C>T	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrA	9152	c.1851C>T	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrA	9153	p.Thr618Glu	missense_variant	0.91	levofloxacin
gyrA	9153	p.Thr618Glu	missense_variant	0.91	moxifloxacin
gyrA	9158	c.1857C>T	synonymous_variant	0.91	levofloxacin	Not assoc w R - Interim
gyrA	9158	c.1857C>T	synonymous_variant	0.91	moxifloxacin	Not assoc w R - Interim
gyrA	9161	c.1860C>G	synonymous_variant	0.91	levofloxacin
gyrA	9161	c.1860C>G	synonymous_variant	0.91	moxifloxacin
gyrA	9182	c.1881T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	9182	c.1881T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	9191	c.1890G>C	synonymous_variant	0.92	levofloxacin
gyrA	9191	c.1890G>C	synonymous_variant	0.92	moxifloxacin
gyrA	9200	c.1899A>G	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	9200	c.1899A>G	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	9204	p.Ser635Thr	missense_variant	0.92	levofloxacin
gyrA	9204	p.Ser635Thr	missense_variant	0.92	moxifloxacin
gyrA	9224	c.1923C>T	synonymous_variant	0.92	levofloxacin
gyrA	9224	c.1923C>T	synonymous_variant	0.92	moxifloxacin
gyrA	9230	c.1929T>C	synonymous_variant	0.93	levofloxacin
gyrA	9230	c.1929T>C	synonymous_variant	0.93	moxifloxacin
gyrA	9233	c.1932C>G	synonymous_variant	0.93	levofloxacin
gyrA	9233	c.1932C>G	synonymous_variant	0.93	moxifloxacin
gyrA	9239	c.1938C>T	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrA	9239	c.1938C>T	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	9252	p.Val651Ile	missense_variant	0.96	levofloxacin	Uncertain significance
gyrA	9252	p.Val651Ile	missense_variant	0.96	moxifloxacin	Uncertain significance
gyrA	9284	c.1983T>C	synonymous_variant	1.0	levofloxacin
gyrA	9284	c.1983T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9291	c.1990C>T	synonymous_variant	1.0	levofloxacin
gyrA	9291	c.1990C>T	synonymous_variant	1.0	moxifloxacin
gyrA	9296	c.1995T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9296	c.1995T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9299	c.1998G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9299	c.1998G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9300	p.Ala667Ser	missense_variant	1.0	levofloxacin
gyrA	9300	p.Ala667Ser	missense_variant	1.0	moxifloxacin
gyrA	9304	p.Gly668Asp	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	9304	p.Gly668Asp	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	9308	p.Asp669Glu	missense_variant	1.0	levofloxacin
gyrA	9308	p.Asp669Glu	missense_variant	1.0	moxifloxacin
gyrA	9323	c.2022C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9323	c.2022C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9335	c.2034G>C	synonymous_variant	1.0	levofloxacin
gyrA	9335	c.2034G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9365	c.2064G>A	synonymous_variant	1.0	levofloxacin
gyrA	9365	c.2064G>A	synonymous_variant	1.0	moxifloxacin
gyrA	9374	c.2073G>C	synonymous_variant	1.0	levofloxacin
gyrA	9374	c.2073G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9377	c.2076A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9377	c.2076A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9383	c.2082T>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9383	c.2082T>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9386	c.2085T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9386	c.2085T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9398	c.2097T>C	synonymous_variant	1.0	levofloxacin
gyrA	9398	c.2097T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9566	c.2265C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9566	c.2265C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9572	c.2271C>G	synonymous_variant	1.0	levofloxacin
gyrA	9572	c.2271C>G	synonymous_variant	1.0	moxifloxacin
gyrA	9578	c.2277C>T	synonymous_variant	1.0	levofloxacin
gyrA	9578	c.2277C>T	synonymous_variant	1.0	moxifloxacin
gyrA	9582	c.2281A>C	synonymous_variant	1.0	levofloxacin
gyrA	9582	c.2281A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9585	c.2284T>C	synonymous_variant	1.0	levofloxacin
gyrA	9585	c.2284T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9590	c.2289T>C	synonymous_variant	1.0	levofloxacin
gyrA	9590	c.2289T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9593	c.2292G>C	synonymous_variant	1.0	levofloxacin
gyrA	9593	c.2292G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9602	c.2301T>C	synonymous_variant	1.0	levofloxacin
gyrA	9602	c.2301T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9611	p.Asp770Glu	missense_variant	1.0	levofloxacin
gyrA	9611	p.Asp770Glu	missense_variant	1.0	moxifloxacin
gyrA	9626	c.2325T>C	synonymous_variant	1.0	levofloxacin
gyrA	9626	c.2325T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9629	c.2328C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9629	c.2328C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9630	p.Val777Ile	missense_variant	1.0	levofloxacin
gyrA	9630	p.Val777Ile	missense_variant	1.0	moxifloxacin
gyrA	9635	c.2334T>C	synonymous_variant	1.0	levofloxacin
gyrA	9635	c.2334T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9638	c.2337C>G	synonymous_variant	1.0	levofloxacin
gyrA	9638	c.2337C>G	synonymous_variant	1.0	moxifloxacin
gyrA	9641	c.2340C>A	synonymous_variant	1.0	levofloxacin
gyrA	9641	c.2340C>A	synonymous_variant	1.0	moxifloxacin
gyrA	9644	c.2343T>C	synonymous_variant	1.0	levofloxacin
gyrA	9644	c.2343T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9650	c.2349G>C	synonymous_variant	1.0	levofloxacin
gyrA	9650	c.2349G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9656	c.2355C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9656	c.2355C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9665	c.2364A>C	synonymous_variant	1.0	levofloxacin
gyrA	9665	c.2364A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9666	p.Arg789Gly	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	9666	p.Arg789Gly	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	9674	c.2373T>C	synonymous_variant	1.0	levofloxacin
gyrA	9674	c.2373T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9704	c.2403T>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9704	c.2403T>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
ccsA	619507	c.-384A>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619528	c.-363C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619531	c.-360T>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619535	c.-356_-354delCAAinsGCG	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619543	c.-348C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619552	c.-339A>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619555	c.-336C>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619561	c.-330G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619570	c.-321G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619574	c.-317G>A	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619579	c.-312G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619584	c.-307A>T	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619591	c.-300G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619609	c.-282G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619634	c.-257T>A	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619645	c.-246G>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	619654	c.-237A>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620265	c.375C>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620268	c.378G>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620283	c.393T>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620284	p.Ala132Pro	missense_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620288	p.Arg133Gln	missense_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620295	c.405G>T	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620298	c.408G>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620310	c.420C>T	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620317	p.Val143Leu	missense_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620340	c.450C>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620346	c.456C>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620362	p.Ala158Thr	missense_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620367	c.477T>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620373	c.483C>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620376	c.486G>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620385	c.495G>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620388	c.498A>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620389	c.499C>T	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620412	c.522T>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620415	c.525T>C	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
ccsA	620421	c.531G>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620424	c.534G>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620433	c.543C>G	synonymous_variant	1.0	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
ccsA	620436	c.546T>A	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620439	c.549T>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620445	c.555A>G	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620583	c.693G>C	synonymous_variant	0.75	kanamycin
					capreomycin
					amikacin
ccsA	620586	c.696C>G	synonymous_variant	0.79	kanamycin
					capreomycin
					amikacin
ccsA	620598	c.708C>G	synonymous_variant	0.81	kanamycin
					capreomycin
					amikacin
ccsA	620601	c.711C>T	synonymous_variant	0.81	kanamycin
					capreomycin
					amikacin
ccsA	620604	c.714C>G	synonymous_variant	0.81	kanamycin
					capreomycin
					amikacin
ccsA	620607	c.717T>C	synonymous_variant	0.76	kanamycin
					capreomycin
					amikacin
ccsA	620613	c.723C>G	synonymous_variant	0.79	kanamycin
					capreomycin
					amikacin
ccsA	620622	c.732G>C	synonymous_variant	0.81	kanamycin
					capreomycin
					amikacin
ccsA	620625	c.735A>C	synonymous_variant	1.0	kanamycin
					capreomycin
					amikacin
ccsA	620631	c.741T>G	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620646	c.756G>A	synonymous_variant	0.88	kanamycin
					capreomycin
					amikacin
ccsA	620649	c.759A>G	synonymous_variant	0.88	kanamycin
					capreomycin
					amikacin
ccsA	620659	c.769_771delCGCinsAGG	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620664	c.774C>T	synonymous_variant	0.86	kanamycin
					capreomycin
					amikacin
ccsA	620682	c.792G>A	synonymous_variant	0.9	kanamycin
					capreomycin
					amikacin
ccsA	620688	c.798G>C	synonymous_variant	0.92	kanamycin
					capreomycin
					amikacin
ccsA	620710	p.Val274Ile	missense_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620718	c.828G>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620721	c.831G>C	synonymous_variant	0.93	kanamycin
					capreomycin
					amikacin
ccsA	620733	c.843G>C	synonymous_variant	0.97	kanamycin
					capreomycin
					amikacin
ccsA	620734	c.844C>A	synonymous_variant	0.97	kanamycin
					capreomycin
					amikacin
ccsA	620739	c.849A>G	synonymous_variant	0.92	kanamycin
					capreomycin
					amikacin
ccsA	620742	c.852G>C	synonymous_variant	0.92	kanamycin
					capreomycin
					amikacin
ccsA	620745	c.855G>C	synonymous_variant	0.92	kanamycin
					capreomycin
					amikacin
ccsA	620748	c.858T>A	synonymous_variant	0.92	kanamycin
					capreomycin
					amikacin
ccsA	620763	c.873G>A	synonymous_variant	0.94	kanamycin
					capreomycin
					amikacin
ccsA	620769	c.879C>G	synonymous_variant	0.94	kanamycin	Not assoc w R - Interim
					capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
ccsA	620778	c.888T>C	synonymous_variant	0.91	kanamycin
					capreomycin
					amikacin
ccsA	620784	c.894C>G	synonymous_variant	0.91	kanamycin
					capreomycin
					amikacin
ccsA	620790	c.900C>T	synonymous_variant	0.9	kanamycin
					capreomycin
					amikacin
ccsA	620796	c.906C>G	synonymous_variant	0.9	kanamycin
					capreomycin
					amikacin
ccsA	620809	c.919C>T	synonymous_variant	0.94	kanamycin
					capreomycin
					amikacin
Rv0565c	656192	p.Asp427Asn	missense_variant	1.0	ethionamide	Uncertain significance
Rv0565c	656196	p.Leu425Arg	missense_variant	1.0	ethionamide
Rv0565c	656219	p.His418Tyr	missense_variant	0.94	ethionamide
Rv0565c	656220	c.1251A>C	synonymous_variant	0.94	ethionamide
Rv0565c	656223	c.1248T>C	synonymous_variant	0.94	ethionamide	Not assoc w R - Interim
Rv0565c	656226	p.Ala415Ser	missense_variant	0.94	ethionamide
Rv0565c	656238	p.Ala411Glu	missense_variant	0.89	ethionamide
Rv0565c	656243	p.Leu410Met	missense_variant	0.89	ethionamide
Rv0565c	656244	c.1227A>C	synonymous_variant	0.89	ethionamide
Rv0565c	656265	c.1206G>C	synonymous_variant	0.89	ethionamide
Rv0565c	656268	p.Met401Ile	missense_variant	0.89	ethionamide
Rv0565c	656277	c.1194C>G	synonymous_variant	0.89	ethionamide
Rv0565c	656289	c.1182C>G	synonymous_variant	0.92	ethionamide
Rv0565c	656298	c.1173G>C	synonymous_variant	0.93	ethionamide
Rv0565c	656304	c.1167T>C	synonymous_variant	0.93	ethionamide
Rv0565c	656325	c.1146C>G	synonymous_variant	0.92	ethionamide
Rv0565c	656358	c.1113T>C	synonymous_variant	0.93	ethionamide	Not assoc w R - Interim
Rv0565c	656361	c.1110C>G	synonymous_variant	0.93	ethionamide
Rv0565c	656364	c.1107T>C	synonymous_variant	0.93	ethionamide
Rv0565c	656367	c.1101_1104delTCGGinsGC	frameshift_variant&synonymous_variant	0.93	ethionamide	Uncertain significance
Rv0565c	656371	p.Pro367His	missense_variant	0.93	ethionamide
Rv0565c	656375	c.1095_1096insAA	frameshift_variant	0.88	ethionamide	Uncertain significance
Rv0565c	656383	p.Val363Asn	missense_variant	1.0	ethionamide
Rv0565c	656391	c.1080C>G	synonymous_variant	1.0	ethionamide
Rv0565c	656402	p.Ala357Thr	missense_variant	1.0	ethionamide
Rv0565c	656412	c.1059T>G	synonymous_variant	1.0	ethionamide
Rv0565c	656418	c.1053A>G	synonymous_variant	1.0	ethionamide
Rv0565c	656423	c.1048T>C	synonymous_variant	1.0	ethionamide
Rv0565c	656448	p.Ile341Val	missense_variant	1.0	ethionamide
Rv0565c	656454	c.1017G>C	synonymous_variant	1.0	ethionamide
Rv0565c	656457	c.1014T>C	synonymous_variant	1.0	ethionamide
Rv0565c	656469	c.1002T>C	synonymous_variant	1.0	ethionamide
Rv0565c	656475	c.996A>G	synonymous_variant	1.0	ethionamide
Rv0565c	656484	c.987T>C	synonymous_variant	1.0	ethionamide
Rv0565c	656487	c.984T>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
Rv0565c	656493	c.978C>G	synonymous_variant	1.0	ethionamide
Rv0565c	656502	c.969C>T	synonymous_variant	1.0	ethionamide
Rv0565c	656511	c.960T>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
Rv0565c	657300	c.171C>G	synonymous_variant	1.0	ethionamide
Rv0565c	657689	c.-220_-219delCAinsAC	upstream_gene_variant	0.83	ethionamide
Rv0565c	657701	c.-231C>G	upstream_gene_variant	0.86	ethionamide
Rv0565c	657734	c.-264T>C	upstream_gene_variant	0.81	ethionamide
nusG	734407	p.Val52Ile	missense_variant	1.0	rifampicin
nusG	734421	c.168A>G	synonymous_variant	1.0	rifampicin
nusG	734424	c.171G>A	synonymous_variant	1.0	rifampicin
nusG	734442	c.189G>A	synonymous_variant	0.94	rifampicin
nusG	734451	c.198G>C	synonymous_variant	0.94	rifampicin
nusG	734457	c.204C>G	synonymous_variant	0.94	rifampicin
nusG	734472	c.219T>C	synonymous_variant	0.9	rifampicin
nusG	734475	c.222T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
nusG	734499	c.246G>C	synonymous_variant	0.86	rifampicin
nusG	734532	c.279A>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
nusG	734541	c.288A>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	760091	c.285G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760101	c.295T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760112	c.306T>C	synonymous_variant	1.0	rifampicin
rpoB	760118	c.312T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760121	c.315T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760130	p.Asp108Glu	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760139	c.333A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760142	c.336C>G	synonymous_variant	1.0	rifampicin
rpoB	760181	c.375T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760184	c.378A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760196	c.390C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760223	c.417T>C	synonymous_variant	1.0	rifampicin
rpoB	760235	c.429T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760298	c.492G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760307	c.501T>C	synonymous_variant	1.0	rifampicin
rpoB	760310	c.504G>C	synonymous_variant	1.0	rifampicin
rpoB	760328	c.522G>C	synonymous_variant	1.0	rifampicin
rpoB	760331	c.525G>C	synonymous_variant	1.0	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760361	c.555T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760370	c.564C>G	synonymous_variant	0.93	rifampicin
rpoB	760376	p.Asp190Glu	missense_variant	0.9	rifampicin	Uncertain significance
rpoB	760380	p.Thr192Leu	missense_variant	0.9	rifampicin
rpoB	760406	c.600G>C	synonymous_variant	0.9	rifampicin
rpoB	760412	c.606C>G	synonymous_variant	0.89	rifampicin
rpoB	760424	c.618C>G	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	760475	c.669A>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	760484	c.678A>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoB	760522	p.Ser239Asn	missense_variant	0.94	rifampicin	Uncertain significance
rpoB	760532	c.726T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Thr	missense_variant	1.0	rifampicin
rpoB	760541	c.735G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760547	c.741G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760563	p.Arg253Met	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760591	p.Val262Ala	missense_variant	0.88	rifampicin
rpoB	760611	c.805T>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	760646	c.840C>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	760655	c.849A>G	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoB	760661	c.855A>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>C	synonymous_variant	0.85	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	760715	c.909C>G	synonymous_variant	0.87	rifampicin
rpoB	760718	c.912C>T	synonymous_variant	0.87	rifampicin
rpoB	760724	c.918T>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	760730	c.924T>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	760751	c.945G>C	synonymous_variant	0.92	rifampicin
rpoB	760757	c.951T>C	synonymous_variant	0.92	rifampicin
rpoB	760759	p.Val318Ala	missense_variant	0.92	rifampicin
rpoB	760769	c.963C>G	synonymous_variant	0.91	rifampicin
rpoB	760775	c.969G>C	synonymous_variant	0.91	rifampicin
rpoB	760776	c.970_972delTCGinsAGC	synonymous_variant	0.91	rifampicin
rpoB	760793	c.987A>G	synonymous_variant	0.85	rifampicin
rpoB	760805	c.999G>C	synonymous_variant	0.83	rifampicin
rpoB	760925	c.1119T>C	synonymous_variant	0.88	rifampicin
rpoB	760928	c.1122G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	760931	c.1125C>G	synonymous_variant	0.88	rifampicin
rpoB	760934	c.1128C>T	synonymous_variant	0.88	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760982	c.1176G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760985	c.1179G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760991	c.1185G>C	synonymous_variant	0.97	rifampicin
rpoB	761006	c.1200C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761015	c.1209G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761021	c.1215G>C	synonymous_variant	0.96	rifampicin
rpoB	761027	c.1221A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761036	c.1230G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761057	c.1251G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761102	c.1296A>G	synonymous_variant	1.0	rifampicin
rpoB	761129	c.1323G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761132	c.1326G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761133	c.1327T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761153	c.1347G>C	synonymous_variant	1.0	rifampicin
rpoB	761165	c.1359G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761180	c.1374A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761189	c.1383T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761195	c.1389G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761207	c.1401C>T	synonymous_variant	1.0	rifampicin
rpoB	761213	c.1407G>C	synonymous_variant	1.0	rifampicin
rpoB	761219	c.1413G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761249	c.1443A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761255	c.1449T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761261	c.1455G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761531	c.1725C>G	synonymous_variant	1.0	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761570	c.1764T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761588	c.1782C>T	synonymous_variant	1.0	rifampicin
rpoB	761606	c.1800C>G	synonymous_variant	1.0	rifampicin
rpoB	761612	c.1806G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761645	c.1839C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761648	c.1842T>C	synonymous_variant	1.0	rifampicin
rpoB	761657	c.1851C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761675	c.1869G>C	synonymous_variant	1.0	rifampicin
rpoB	761720	c.1914C>G	synonymous_variant	0.93	rifampicin
rpoB	761723	c.1917_1919delAGAinsC	frameshift_variant&missense_variant	0.93	rifampicin
rpoB	761732	c.1926C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761735	c.1929C>G	synonymous_variant	0.94	rifampicin
rpoB	761747	c.1941G>C	synonymous_variant	0.89	rifampicin
rpoB	761750	c.1944G>C	synonymous_variant	0.89	rifampicin
rpoB	761765	c.1959T>C	synonymous_variant	0.91	rifampicin
rpoB	761772	p.His656Ala	missense_variant	0.91	rifampicin
rpoB	761778	p.Asn658Asp	missense_variant	0.91	rifampicin
rpoB	761791	p.Arg662His	missense_variant	0.91	rifampicin
rpoB	761813	c.2007T>C	synonymous_variant	0.9	rifampicin
rpoB	761815	p.Ala670Glu	missense_variant	0.9	rifampicin
rpoB	761834	c.2028T>C	synonymous_variant	0.91	rifampicin
rpoB	761848	p.Cys681Ser	missense_variant	0.96	rifampicin
rpoB	761852	c.2046C>G	synonymous_variant	0.95	rifampicin
rpoB	761858	c.2052G>C	synonymous_variant	0.92	rifampicin
rpoB	761873	c.2067A>C	synonymous_variant	0.96	rifampicin
rpoB	761885	c.2079T>C	synonymous_variant	0.96	rifampicin
rpoB	761906	c.2100C>A	synonymous_variant	1.0	rifampicin
rpoB	761909	c.2103T>C	synonymous_variant	1.0	rifampicin
rpoB	761912	c.2106T>C	synonymous_variant	1.0	rifampicin
rpoB	761915	p.Asp703Glu	missense_variant	1.0	rifampicin
rpoB	761916	p.Asp704Asn	missense_variant	1.0	rifampicin
rpoB	761948	c.2142G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761954	c.2148C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762008	c.2202C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762014	c.2208C>T	synonymous_variant	1.0	rifampicin
rpoB	762017	c.2211A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762053	c.2247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762062	c.2256T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762101	c.2295C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762131	c.2325C>G	synonymous_variant	1.0	rifampicin
rpoB	762140	c.2334G>C	synonymous_variant	1.0	rifampicin
rpoB	762143	c.2337T>C	synonymous_variant	1.0	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762167	c.2361T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762170	c.2364C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762185	c.2379G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762233	c.2427G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762246	c.2440C>T	synonymous_variant	1.0	rifampicin
rpoB	762254	c.2448T>G	synonymous_variant	1.0	rifampicin
rpoB	762257	c.2451C>G	synonymous_variant	1.0	rifampicin
rpoB	762284	c.2478G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762449	c.2643C>A	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	762467	c.-903C>T	upstream_gene_variant	0.92	rifampicin
rpoB	762488	c.2682G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	762489	p.Val895Gln	missense_variant	0.92	rifampicin
rpoC	762509	c.-861T>G	upstream_gene_variant	1.0	rifampicin
rpoB	762510	p.Ala902Pro	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	762521	c.-849C>T	upstream_gene_variant	1.0	rifampicin
rpoC	762533	c.-837T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762537	c.-833T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762551	c.-819C>G	upstream_gene_variant	1.0	rifampicin
rpoB	762857	c.3051C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762860	c.3054G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762863	c.3057T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762929	c.3123G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762989	c.-381G>C	upstream_gene_variant	0.93	rifampicin
rpoB	762995	c.3189G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	763013	c.-357C>G	upstream_gene_variant	0.89	rifampicin
rpoB	763115	c.3309T>C	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoB	763136	c.3330C>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	763148	c.-222G>C	upstream_gene_variant	0.93	rifampicin
rpoC	763158	c.-212C>T	upstream_gene_variant	0.96	rifampicin
rpoB	763166	c.3360A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763190	c.-180C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	1.0	rifampicin
rpoC	763205	c.-165G>C	upstream_gene_variant	1.0	rifampicin
rpoC	763206	c.-164_-162delAGTinsTCG	upstream_gene_variant	1.0	rifampicin
rpoB	763214	c.3408T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763226	c.-144A>G	upstream_gene_variant	1.0	rifampicin
rpoB	763227	c.3421C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763238	c.3432T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763253	c.-117G>C	upstream_gene_variant	1.0	rifampicin
rpoC	763256	c.-114G>A	upstream_gene_variant	1.0	rifampicin
rpoC	763807	c.438T>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	763816	c.447C>G	synonymous_variant	0.87	rifampicin
rpoC	763835	p.Ala156Met	missense_variant	0.87	rifampicin
rpoC	763853	p.Val162Ile	missense_variant	0.87	rifampicin
rpoC	763858	c.489A>G	synonymous_variant	0.86	rifampicin
rpoC	763872	p.Gly168Ala	missense_variant	0.88	rifampicin
rpoC	763876	p.Glu169Asp	missense_variant	0.88	rifampicin
rpoC	763879	c.510A>G	synonymous_variant	0.88	rifampicin
rpoC	763888	c.519G>C	synonymous_variant	0.86	rifampicin
rpoC	763891	c.522G>C	synonymous_variant	0.86	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	0.86	rifampicin
rpoC	763900	c.531G>C	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoC	763945	c.576T>C	synonymous_variant	1.0	rifampicin
rpoC	763987	c.618C>T	synonymous_variant	1.0	rifampicin
rpoC	763991	p.Ile208Leu	missense_variant	1.0	rifampicin
rpoC	763996	c.627T>C	synonymous_variant	1.0	rifampicin
rpoC	764002	c.633C>G	synonymous_variant	1.0	rifampicin
rpoC	764005	c.636G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764024	c.655_657delTTGinsCTC	synonymous_variant	1.0	rifampicin
rpoC	764032	p.Asp221Glu	missense_variant	1.0	rifampicin
rpoC	764040	p.Ser224Thr	missense_variant	1.0	rifampicin
rpoC	764044	c.675T>C	synonymous_variant	1.0	rifampicin
rpoC	764059	c.690G>T	synonymous_variant	1.0	rifampicin
rpoC	764083	c.714A>G	synonymous_variant	1.0	rifampicin
rpoC	764098	c.729A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764101	c.732C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764102	p.Val245Ile	missense_variant	1.0	rifampicin
rpoC	764112	p.Tyr248Phe	missense_variant	1.0	rifampicin
rpoC	764116	c.747C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764131	c.762T>C	synonymous_variant	1.0	rifampicin
rpoC	764188	c.819A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764195	p.Ser276Ile	missense_variant	1.0	rifampicin
rpoC	764203	c.834G>C	synonymous_variant	1.0	rifampicin
rpoC	764206	c.837T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764215	c.846A>G	synonymous_variant	1.0	rifampicin
rpoC	764236	c.867G>A	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764248	c.879C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764257	c.888G>C	synonymous_variant	0.97	rifampicin
rpoC	764266	c.897T>C	synonymous_variant	0.96	rifampicin
rpoC	764269	c.900G>C	synonymous_variant	0.96	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	0.96	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764338	c.969G>A	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764353	c.984G>C	synonymous_variant	0.9	rifampicin
rpoC	764405	c.1036A>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764419	c.1050C>G	synonymous_variant	0.93	rifampicin
rpoC	764428	c.1059G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764431	c.1062G>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	764434	c.1065A>G	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	764446	c.1077T>C	synonymous_variant	0.88	rifampicin
rpoC	764449	c.1080G>C	synonymous_variant	0.88	rifampicin
rpoC	764452	c.1083T>C	synonymous_variant	0.87	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764489	c.1120C>T	synonymous_variant	0.96	rifampicin
rpoC	764497	c.1128A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764510	c.1141C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764521	c.1152T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764527	c.1158C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>C	synonymous_variant	0.96	rifampicin
rpoC	764539	c.1170C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764548	c.1179G>A	synonymous_variant	0.96	rifampicin
rpoC	764551	c.1182G>C	synonymous_variant	0.96	rifampicin
rpoC	764554	c.1185C>T	synonymous_variant	0.93	rifampicin
rpoC	764560	c.1191T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764566	c.1197C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764575	c.1206T>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764593	c.1224C>T	synonymous_variant	1.0	rifampicin
rpoC	764611	c.1242G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>C	synonymous_variant	1.0	rifampicin
rpoC	764651	c.1282_1284delTCGinsAGC	synonymous_variant	1.0	rifampicin
rpoC	764752	c.1383G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764764	c.1395T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764809	c.1440C>T	synonymous_variant	1.0	rifampicin	Not assoc w R
rpoC	764815	c.1446A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764827	c.1458G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764858	c.1489T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764872	c.1503A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764911	c.1542A>G	synonymous_variant	1.0	rifampicin
rpoC	764932	c.1563C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764948	c.1579T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764968	c.1599T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765529	c.2160C>T	synonymous_variant	1.0	rifampicin
rpoC	765541	c.2172C>G	synonymous_variant	1.0	rifampicin
rpoC	765553	c.2184C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765556	c.2187G>C	synonymous_variant	1.0	rifampicin
rpoC	765559	c.2190G>C	synonymous_variant	1.0	rifampicin
rpoC	765580	c.2211G>C	synonymous_variant	1.0	rifampicin
rpoC	765613	p.His748Gln	missense_variant	1.0	rifampicin
rpoC	765625	c.2256C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765631	p.Asp754Glu	missense_variant	1.0	rifampicin
rpoC	765700	c.2331T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765734	c.2365T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765739	c.2370G>T	synonymous_variant	1.0	rifampicin
rpoC	765751	c.2382C>G	synonymous_variant	1.0	rifampicin
rpoC	765753	p.Asp795Ala	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	765772	c.2403C>G	synonymous_variant	1.0	rifampicin
rpoC	765784	c.2415C>G	synonymous_variant	1.0	rifampicin
rpoC	765787	c.2418C>T	synonymous_variant	1.0	rifampicin
rpoC	765793	c.2424C>G	synonymous_variant	1.0	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	1.0	rifampicin
rpoC	765811	c.2442T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765814	c.2445A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765826	c.2457T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765835	c.2466C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765850	c.2481G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765883	c.2514C>G	synonymous_variant	1.0	rifampicin
rpoC	765886	c.2517C>G	synonymous_variant	1.0	rifampicin
rpoC	765892	c.2523T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766363	c.2994G>C	synonymous_variant	1.0	rifampicin
rpoC	766366	c.2997C>G	synonymous_variant	1.0	rifampicin
rpoC	766381	c.3012C>T	synonymous_variant	0.92	rifampicin
rpoC	766384	c.3015A>G	synonymous_variant	1.0	rifampicin
rpoC	766390	c.3021C>T	synonymous_variant	1.0	rifampicin
rpoC	766393	c.3024C>G	synonymous_variant	1.0	rifampicin
rpoC	766408	c.3039C>G	synonymous_variant	1.0	rifampicin
rpoC	766411	c.3042C>G	synonymous_variant	1.0	rifampicin
rpoC	766426	c.3057C>T	synonymous_variant	1.0	rifampicin
rpoC	766447	c.3078T>C	synonymous_variant	1.0	rifampicin
rpoC	766462	c.3093G>C	synonymous_variant	1.0	rifampicin
rpoC	766483	c.3114G>C	synonymous_variant	1.0	rifampicin
rpoC	766484	p.Val1039Ile	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	766492	c.3123T>C	synonymous_variant	1.0	rifampicin
rpoC	766522	c.3153C>G	synonymous_variant	1.0	rifampicin
rpoC	766528	c.3159T>C	synonymous_variant	1.0	rifampicin
rpoC	766531	c.3162G>C	synonymous_variant	1.0	rifampicin
rpoC	766540	p.Asp1057Glu	missense_variant	1.0	rifampicin
rpoC	766549	c.3180G>C	synonymous_variant	1.0	rifampicin
rpoC	766573	c.3204T>C	synonymous_variant	1.0	rifampicin
rpoC	766582	c.3213C>G	synonymous_variant	1.0	rifampicin
rpoC	766583	p.Gly1072Ser	missense_variant	1.0	rifampicin
rpoC	766591	c.3222A>G	synonymous_variant	1.0	rifampicin
rpoC	766594	c.3225G>C	synonymous_variant	1.0	rifampicin
rpoC	766597	c.3228C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766607	p.Ile1080Leu	missense_variant	1.0	rifampicin
rpoC	766630	c.3261G>C	synonymous_variant	1.0	rifampicin
rpoC	766657	c.3288A>G	synonymous_variant	1.0	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	1.0	rifampicin
rpoC	766673	p.Gly1102Asn	missense_variant	1.0	rifampicin
rpoC	766726	c.3357T>C	synonymous_variant	1.0	rifampicin
rpoC	766738	c.3369G>C	synonymous_variant	1.0	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766774	c.3405T>C	synonymous_variant	1.0	rifampicin
rpoC	766801	c.3432C>G	synonymous_variant	0.98	rifampicin
rpoC	766804	c.3435A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766861	c.3492G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766864	c.3495G>C	synonymous_variant	0.98	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	0.96	rifampicin
rpoC	766933	c.3564A>G	synonymous_variant	0.96	rifampicin
rpoC	766945	c.3576A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766963	c.3594T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766972	c.3603G>C	synonymous_variant	0.98	rifampicin
rpoC	766996	c.3627C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	767009	c.3640_3642delTCGinsAGC	synonymous_variant	0.98	rifampicin
rpoC	767014	c.3645G>C	synonymous_variant	0.98	rifampicin
rpoC	767033	c.3664_3666delTCGinsAGC	synonymous_variant	1.0	rifampicin
rpoC	767059	c.3690T>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	767062	c.3693C>A	synonymous_variant	0.97	rifampicin
rpoC	767098	c.3729T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	767119	c.3750A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	767134	c.3765C>A	synonymous_variant	0.95	rifampicin
rpoC	767158	c.3789T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	767180	p.Ala1271Gln	missense_variant	0.91	rifampicin
rpoC	767191	c.3822C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	767206	c.3837C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	767209	c.3840T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	767212	c.3843G>C	synonymous_variant	0.95	rifampicin
rpoC	767221	c.3852C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	767230	c.3861G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
mmpL5	777133	p.Val450Ile	missense_variant	1.0	bedaquiline
mmpL5	777133	p.Val450Ile	missense_variant	1.0	clofazimine
mmpL5	777158	c.1323C>G	synonymous_variant	1.0	bedaquiline
mmpL5	777158	c.1323C>G	synonymous_variant	1.0	clofazimine
mmpL5	777164	c.1317C>G	synonymous_variant	1.0	bedaquiline
mmpL5	777164	c.1317C>G	synonymous_variant	1.0	clofazimine
mmpL5	777170	c.1311T>C	synonymous_variant	1.0	bedaquiline
mmpL5	777170	c.1311T>C	synonymous_variant	1.0	clofazimine
mmpL5	777176	p.Glu435Asp	missense_variant	1.0	bedaquiline
mmpL5	777176	p.Glu435Asp	missense_variant	1.0	clofazimine
mmpL5	777191	c.1290C>G	synonymous_variant	1.0	bedaquiline
mmpL5	777191	c.1290C>G	synonymous_variant	1.0	clofazimine
mmpL5	777194	c.1287A>G	synonymous_variant	1.0	bedaquiline
mmpL5	777194	c.1287A>G	synonymous_variant	1.0	clofazimine
mmpL5	777206	c.1275A>G	synonymous_variant	1.0	bedaquiline
mmpL5	777206	c.1275A>G	synonymous_variant	1.0	clofazimine
rpsL	781832	c.273T>C	synonymous_variant	1.0	streptomycin
rpsL	781838	c.279G>C	synonymous_variant	1.0	streptomycin
rpsL	781841	c.282C>G	synonymous_variant	1.0	streptomycin
rpsL	781865	c.306G>C	synonymous_variant	1.0	streptomycin
rpsL	781868	c.309T>C	synonymous_variant	1.0	streptomycin
rpsL	781871	c.312G>C	synonymous_variant	1.0	streptomycin
rpsL	781877	c.318T>C	synonymous_variant	1.0	streptomycin
rpsL	781892	c.333A>G	synonymous_variant	1.0	streptomycin
rpsL	781898	c.339A>T	synonymous_variant	1.0	streptomycin
rpsL	781916	c.357T>C	synonymous_variant	1.0	streptomycin
rpsL	781929	p.Gly124Ser	missense_variant	1.0	streptomycin	Uncertain significance
rplC	800516	c.-293G>T	upstream_gene_variant	0.94	linezolid
rplC	800537	c.-272C>T	upstream_gene_variant	0.95	linezolid
rplC	800540	c.-269T>C	upstream_gene_variant	0.96	linezolid
rplC	800546	c.-263T>G	upstream_gene_variant	0.96	linezolid
rplC	800567	c.-242A>G	upstream_gene_variant	0.9	linezolid
rplC	800582	c.-227C>G	upstream_gene_variant	0.91	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	0.92	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	0.93	linezolid
rplC	800627	c.-182C>T	upstream_gene_variant	0.93	linezolid
rplC	800648	c.-161A>T	upstream_gene_variant	0.91	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.93	linezolid
rplC	800693	c.-116A>G	upstream_gene_variant	0.93	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.93	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	0.96	linezolid
rplC	800720	c.-89T>C	upstream_gene_variant	0.98	linezolid
rplC	800723	c.-86C>G	upstream_gene_variant	0.98	linezolid
rplC	800747	c.-62C>G	upstream_gene_variant	0.97	linezolid
rplC	800771	c.-38C>T	upstream_gene_variant	0.97	linezolid
rplC	800794	c.-15A>G	upstream_gene_variant	1.0	linezolid
rplC	800796	c.-13A>G	upstream_gene_variant	1.0	linezolid
rplC	800798	c.-10_-9delGG	upstream_gene_variant	1.0	linezolid
rplC	800814	c.6A>G	synonymous_variant	1.0	linezolid
rplC	800817	c.9A>T	synonymous_variant	1.0	linezolid
rplC	800844	c.36T>C	synonymous_variant	1.0	linezolid
rplC	800865	c.57A>G	synonymous_variant	1.0	linezolid
rplC	800867	p.Ser20Asn	missense_variant	1.0	linezolid
rplC	800874	c.66A>G	synonymous_variant	1.0	linezolid
rplC	800875	p.Val23Ile	missense_variant	1.0	linezolid
rplC	800880	c.72A>G	synonymous_variant	1.0	linezolid
rplC	800889	c.81C>G	synonymous_variant	1.0	linezolid
rplC	800892	c.84G>C	synonymous_variant	1.0	linezolid
rplC	800907	c.99C>G	synonymous_variant	1.0	linezolid
rplC	800916	c.108A>G	synonymous_variant	1.0	linezolid
rplC	800934	c.126C>G	synonymous_variant	1.0	linezolid
rplC	800937	c.129A>G	synonymous_variant	1.0	linezolid
rplC	800939	p.Arg44Gln	missense_variant	1.0	linezolid
rplC	800946	c.138T>C	synonymous_variant	1.0	linezolid
rplC	800949	c.141T>C	synonymous_variant	1.0	linezolid
rplC	800967	c.159C>G	synonymous_variant	1.0	linezolid
rplC	801300	c.492C>G	synonymous_variant	1.0	linezolid
rplC	801309	c.501C>G	synonymous_variant	1.0	linezolid
rplC	801312	c.504G>C	synonymous_variant	1.0	linezolid
rplC	801321	c.513C>T	synonymous_variant	1.0	linezolid	Not assoc w R - Interim
rplC	801324	c.516T>C	synonymous_variant	1.0	linezolid
rplC	801339	c.531T>C	synonymous_variant	1.0	linezolid
rplC	801341	p.Leu178Gln	missense_variant	1.0	linezolid
rplC	801348	c.540T>G	synonymous_variant	1.0	linezolid
rplC	801357	c.549T>C	synonymous_variant	1.0	linezolid
rplC	801367	p.Ala187Thr	missense_variant	1.0	linezolid
rplC	801402	c.594T>C	synonymous_variant	1.0	linezolid
rplC	801405	c.597T>C	synonymous_variant	1.0	linezolid
rplC	801423	c.615G>C	synonymous_variant	1.0	linezolid
rplC	801426	c.618C>G	synonymous_variant	1.0	linezolid
rplC	801427	p.Met207Val	missense_variant	1.0	linezolid
rplC	801438	c.630T>C	synonymous_variant	1.0	linezolid
rplC	801442	p.Ile212Val	missense_variant	1.0	linezolid
fbiC	1303632	c.702T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303641	c.711C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303650	c.720G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303654	c.724C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303659	c.729T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303661	p.Val244Ala	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303663	c.733C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303671	c.741C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine	Not assoc w R - Interim
fbiC	1303674	c.744C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303681	c.751T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303686	c.756C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303695	c.765T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303704	c.774T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303708	c.778T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303728	c.798G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303731	c.801A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303732	p.Ser268Ala	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303737	c.807G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303746	c.816T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303749	c.819G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303752	c.822A>G	synonymous_variant	1.0	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1303755	c.825T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303761	c.831T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303785	c.855G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303789	p.Ile287Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303797	c.867A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303818	c.888C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303836	c.906G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303845	c.915C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303846	p.Phe306Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303854	c.924T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303860	c.930A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303884	c.954T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303905	c.975G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303914	c.984C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303920	c.990C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303944	c.1014G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303947	c.1017T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303948	p.Gly340Arg	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303953	p.Asp341Glu	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303956	c.1026A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303961	p.Arg344Leu	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303971	c.1041T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1303980	c.1050G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304004	c.1074A>G	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304008	c.1078T>C	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304022	c.1092T>C	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304031	c.1101C>G	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1304034	c.1104A>G	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1304040	c.1110C>G	synonymous_variant	0.83	pretomanid
					delamanid
					clofazimine
fbiC	1304046	c.1116C>G	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiC	1304049	c.1119T>C	synonymous_variant	0.8	pretomanid
					delamanid
					clofazimine
fbiC	1304050	c.1120T>C	synonymous_variant	0.8	pretomanid
					delamanid
					clofazimine
fbiC	1304058	c.1128G>A	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiC	1304059	c.1129C>T	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiC	1304064	c.1134G>C	synonymous_variant	0.85	pretomanid
					delamanid
					clofazimine
fbiC	1304067	c.1137G>C	synonymous_variant	0.85	pretomanid
					delamanid
					clofazimine
fbiC	1304085	c.1155C>T	synonymous_variant	0.86	pretomanid
					delamanid
					clofazimine
fbiC	1304091	p.Asp387Glu	missense_variant	0.86	pretomanid
					delamanid
					clofazimine
fbiC	1304092	p.Met388Leu	missense_variant	0.86	pretomanid
					delamanid
					clofazimine
fbiC	1304097	c.1167G>C	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1304127	c.1197A>G	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiC	1304132	p.Ala401Gly	missense_variant	0.8	pretomanid
					delamanid
					clofazimine
fbiC	1304142	c.1212G>C	synonymous_variant	0.8	pretomanid
					delamanid
					clofazimine
fbiC	1304161	p.Arg411Ser	missense_variant	0.71	pretomanid
					delamanid
					clofazimine
fbiC	1304169	c.1239T>C	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiC	1304174	p.Val415Ala	missense_variant	0.69	pretomanid
					delamanid
					clofazimine
fbiC	1304184	c.1254G>C	synonymous_variant	0.69	pretomanid
					delamanid
					clofazimine
fbiC	1304187	c.1257T>C	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiC	1304208	c.1278C>T	synonymous_variant	0.67	pretomanid
					delamanid
					clofazimine
fbiC	1304499	c.1569T>C	synonymous_variant	0.73	pretomanid
					delamanid
					clofazimine
fbiC	1304511	c.1581C>G	synonymous_variant	0.79	pretomanid
					delamanid
					clofazimine
fbiC	1304526	c.1596T>G	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiC	1304535	c.1605G>A	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1304544	c.1614T>C	synonymous_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1304545	p.Val539Thr	missense_variant	0.91	pretomanid
					delamanid
					clofazimine
fbiC	1304553	c.1623C>T	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304559	p.Glu543Asp	missense_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304565	c.1635C>G	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304568	c.1638T>C	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1304580	c.1650T>C	synonymous_variant	0.96	pretomanid
					delamanid
					clofazimine
fbiC	1304613	c.1683T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304634	c.1704C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304640	c.1710A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304646	c.1716T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304658	c.1728C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304661	c.1731C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304670	c.1740G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304671	p.Val581Thr	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304675	p.Gly582Asp	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304691	c.1761G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304694	c.1764A>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304703	c.1773C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304711	p.Ala594Glu	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304715	c.1785G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304724	c.1794A>G	synonymous_variant	1.0	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1304727	c.1797A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304742	c.1812T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304748	c.1818T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304757	c.1827A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304778	c.1848T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304784	c.1854T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304787	c.1857T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304808	c.1878C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304811	c.1881C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304817	c.1887T>C	synonymous_variant	0.97	pretomanid
					delamanid
					clofazimine
fbiC	1304829	c.1899T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304832	c.1902C>T	synonymous_variant	1.0	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1304853	c.1923C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304856	c.1926C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304869	c.1939C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304875	p.Ile649Val	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304883	p.Glu651Asp	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304891	p.Ile654Thr	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304893	p.Gly655Ser	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304907	c.1977C>G	synonymous_variant	0.97	pretomanid
					delamanid
					clofazimine
fbiC	1304910	c.1980G>C	synonymous_variant	0.97	pretomanid
					delamanid
					clofazimine
fbiC	1304916	c.1986T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304928	c.1998T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304937	c.2007G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304958	c.2028T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304983	c.2053C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304994	c.2064A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1304995	p.Leu689Met	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305006	c.2076A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305012	c.2082G>C	synonymous_variant	0.97	pretomanid
					delamanid
					clofazimine
fbiC	1305015	c.2085G>C	synonymous_variant	0.97	pretomanid
					delamanid
					clofazimine
fbiC	1305021	c.2091C>G	synonymous_variant	0.97	pretomanid
					delamanid
					clofazimine
fbiC	1305030	c.2100G>C	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1305033	c.2103T>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1305042	c.2112A>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiC	1305063	c.2133G>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305066	c.2136T>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305069	c.2139G>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305075	c.2145T>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305078	c.2148A>G	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305081	c.2151G>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305090	c.2160C>G	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305092	p.Ala721Gly	missense_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305099	c.2169T>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiC	1305114	c.2184T>C	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1305117	c.2187T>C	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1305126	c.2196T>C	synonymous_variant	0.94	pretomanid
					delamanid	Not assoc w R - Interim
					clofazimine	Not assoc w R - Interim
fbiC	1305135	c.2205C>T	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiC	1305150	c.2220C>G	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1305154	c.2224_2226delTTGinsCTA	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiC	1305173	p.Asn748Ser	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305177	c.2247A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305181	c.2251T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305186	c.2256C>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305195	c.2265T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305201	c.2271G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305204	c.2274C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305210	c.2280G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305215	p.Ser762Thr	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305231	c.2301C>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305234	c.2304G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305240	c.2310T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305243	c.2313T>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine	Not assoc w R - Interim
fbiC	1305244	c.2314T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305252	c.2322G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305276	c.2346G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305279	p.His783Gln	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305282	c.2352T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305297	c.2367G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305300	c.2370A>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305303	c.2373T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305306	c.2376A>T	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305309	c.2379G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305310	p.Arg794Glu	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305318	c.2388C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305331	p.Glu801Asn	missense_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305336	c.2406T>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305372	c.2442G>A	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine	Not assoc w R - Interim
fbiC	1305384	c.2454G>C	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
fbiC	1305396	c.2466C>G	synonymous_variant	1.0	pretomanid
					delamanid
					clofazimine
sigE	1364820	c.408A>G	synonymous_variant	0.81	pyrazinamide
sigE	1364839	c.427_429delTTGinsCTC	synonymous_variant	0.8	pyrazinamide
sigE	1364847	c.435G>C	synonymous_variant	0.86	pyrazinamide
sigE	1364856	c.444C>G	synonymous_variant	0.85	pyrazinamide
sigE	1364862	c.450C>A	synonymous_variant	0.85	pyrazinamide
sigE	1364865	c.453G>C	synonymous_variant	0.85	pyrazinamide
sigE	1364868	c.456T>G	synonymous_variant	0.85	pyrazinamide
sigE	1364887	c.475_477delTTAinsCTG	synonymous_variant	0.83	pyrazinamide
sigE	1364898	c.486C>T	synonymous_variant	0.82	pyrazinamide
sigE	1364904	p.Asp164Glu	missense_variant	0.82	pyrazinamide
sigE	1364919	c.507T>C	synonymous_variant	0.93	pyrazinamide
sigE	1364943	c.531C>T	synonymous_variant	1.0	pyrazinamide
sigE	1364949	c.537C>T	synonymous_variant	1.0	pyrazinamide
sigE	1364950	p.Ala180Ser	missense_variant	1.0	pyrazinamide
sigE	1365000	c.588G>A	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
sigE	1365006	c.594T>C	synonymous_variant	1.0	pyrazinamide
sigE	1365009	c.597C>G	synonymous_variant	1.0	pyrazinamide
sigE	1365012	c.600G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365015	c.603G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365018	c.606G>C	synonymous_variant	1.0	pyrazinamide
sigE	1365024	c.612T>C	synonymous_variant	1.0	pyrazinamide
sigE	1365033	c.621G>A	synonymous_variant	1.0	pyrazinamide
sigE	1365036	c.624T>C	synonymous_variant	1.0	pyrazinamide
sigE	1365042	c.630G>C	synonymous_variant	1.0	pyrazinamide
atpE	1461113	c.69C>T	synonymous_variant	1.0	bedaquiline
atpE	1461132	p.Val30Ile	missense_variant	1.0	bedaquiline
atpE	1461149	c.105T>G	synonymous_variant	1.0	bedaquiline
atpE	1461150	p.Ile36Val	missense_variant	1.0	bedaquiline
atpE	1461158	c.114T>G	synonymous_variant	1.0	bedaquiline
atpE	1461159	p.Val39Ile	missense_variant	1.0	bedaquiline	Uncertain significance
atpE	1461170	c.126A>G	synonymous_variant	1.0	bedaquiline
atpE	1461185	c.141G>T	synonymous_variant	1.0	bedaquiline
atpE	1461197	c.153A>G	synonymous_variant	1.0	bedaquiline
atpE	1461219	c.175T>C	synonymous_variant	1.0	bedaquiline
atpE	1461233	c.189A>C	synonymous_variant	0.92	bedaquiline
rrs	1471934	n.89A>G	non_coding_transcript_exon_variant	0.87	kanamycin
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471969	n.124T>C	non_coding_transcript_exon_variant	0.94	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1471970	n.125G>A	non_coding_transcript_exon_variant	0.94	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472028	n.183A>T	non_coding_transcript_exon_variant	0.98	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472029	n.184C>T	non_coding_transcript_exon_variant	0.93	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472030	n.185G>T	non_coding_transcript_exon_variant	0.93	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472031	n.186G>A	non_coding_transcript_exon_variant	0.93	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472033	n.188A>G	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472034	n.189T>C	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472044	n.199G>T	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472045	n.200T>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472053	n.211_212delGC	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472969	n.1124A>G	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472970	n.1125C>G	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472977	n.1132G>C	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472978	n.1133T>C	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473105	n.1260G>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTT	non_coding_transcript_exon_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473290	n.1445C>T	non_coding_transcript_exon_variant	0.88	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473756	n.99G>A	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1473756	n.99G>A	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1473877	n.220G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473877	n.220G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473945	n.288T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473945	n.288T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473946	n.289A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473946	n.289A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473986	n.329T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473986	n.329T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473987	n.330G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473987	n.330G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	1.0	linezolid	Not assoc w R
rrl	1474009	n.352A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474009	n.352A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474012	n.355C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474012	n.355C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474093	n.436G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474093	n.436G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474291	n.635_649delTTCCTCTCCGGAGGA	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1474291	n.635_649delTTCCTCTCCGGAGGA	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1474376	n.719T>C	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1474376	n.719T>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1474409	n.756_766delACCCACACGCG	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1474409	n.756_766delACCCACACGCG	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1474427	n.770A>C	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1474427	n.770A>C	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1474429	n.772G>C	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1474429	n.772G>C	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1474431	n.774_775delGCinsTTTGGG	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474431	n.774_775delGCinsTTTGGG	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474435	n.780_783delGAAT	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474435	n.780_783delGAAT	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474823	n.1166C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474823	n.1166C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474904	n.1247G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474904	n.1247G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474956	n.1299C>T	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474956	n.1299C>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474960	n.1303C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474960	n.1303C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474963	n.1306G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474963	n.1306G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474964	n.1307T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474964	n.1307T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474965	n.1308G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474965	n.1308G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474970	n.1313G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474970	n.1313G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475006	n.1349A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475006	n.1349A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475088	n.1431A>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475088	n.1431A>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475249	n.1592T>C	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475249	n.1592T>C	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475252	n.1595C>T	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1475252	n.1595C>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475266	n.1609T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475266	n.1609T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475267	n.1610G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475267	n.1610G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475275	n.1618C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475275	n.1618C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475276	n.1619T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475276	n.1619T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475369	n.1712G>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475369	n.1712G>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475402	n.1745C>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475402	n.1745C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475436	n.1779C>T	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475436	n.1779C>T	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475599	n.1942A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475599	n.1942A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475642	n.1985T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475642	n.1985T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475659	n.2002G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475659	n.2002G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475761	n.2104_2106delCGCinsGT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475761	n.2104_2106delCGCinsGT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475765	n.2111delG	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475765	n.2111delG	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476031	n.2374C>T	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1476031	n.2374C>T	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476033	n.2376T>C	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476033	n.2376T>C	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476034	n.2377C>A	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476034	n.2377C>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476048	n.2391G>A	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1476048	n.2391G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1476214	n.2557G>A	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1476214	n.2557G>A	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476726	n.3069A>G	non_coding_transcript_exon_variant	0.89	capreomycin
rrl	1476726	n.3069A>G	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	0.89	capreomycin
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	0.85	capreomycin
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1476755	n.3098G>A	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1476755	n.3098G>A	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	0.77	capreomycin
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	0.77	linezolid
inhA	1673547	c.-655T>C	upstream_gene_variant	1.0	isoniazid
inhA	1673547	c.-655T>C	upstream_gene_variant	1.0	ethionamide
inhA	1673568	c.-634C>G	upstream_gene_variant	1.0	isoniazid
inhA	1673568	c.-634C>G	upstream_gene_variant	1.0	ethionamide
inhA	1673574	c.-628C>G	upstream_gene_variant	1.0	isoniazid
inhA	1673574	c.-628C>G	upstream_gene_variant	1.0	ethionamide
inhA	1673580	c.-622T>G	upstream_gene_variant	1.0	isoniazid	Uncertain significance
inhA	1673580	c.-622T>G	upstream_gene_variant	1.0	ethionamide
inhA	1673589	c.-613A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673589	c.-613A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673595	c.-607A>C	upstream_gene_variant	1.0	isoniazid
inhA	1673595	c.-607A>C	upstream_gene_variant	1.0	ethionamide
inhA	1673596	c.-606A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673596	c.-606A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673602	c.-600C>T	upstream_gene_variant	1.0	isoniazid
inhA	1673602	c.-600C>T	upstream_gene_variant	1.0	ethionamide
inhA	1673607	c.-595T>C	upstream_gene_variant	1.0	isoniazid
inhA	1673607	c.-595T>C	upstream_gene_variant	1.0	ethionamide
inhA	1673615	c.-587_-586delAAinsTG	upstream_gene_variant	1.0	isoniazid
inhA	1673615	c.-587_-586delAAinsTG	upstream_gene_variant	1.0	ethionamide
inhA	1673619	c.-583T>C	upstream_gene_variant	1.0	isoniazid
inhA	1673619	c.-583T>C	upstream_gene_variant	1.0	ethionamide
inhA	1673633	c.-569G>A	upstream_gene_variant	1.0	isoniazid
inhA	1673633	c.-569G>A	upstream_gene_variant	1.0	ethionamide
inhA	1673637	c.-565C>G	upstream_gene_variant	1.0	isoniazid
inhA	1673637	c.-565C>G	upstream_gene_variant	1.0	ethionamide
inhA	1673641	c.-561G>A	upstream_gene_variant	1.0	isoniazid
inhA	1673641	c.-561G>A	upstream_gene_variant	1.0	ethionamide
inhA	1673646	c.-556T>C	upstream_gene_variant	1.0	isoniazid
inhA	1673646	c.-556T>C	upstream_gene_variant	1.0	ethionamide
inhA	1673652	c.-550C>G	upstream_gene_variant	1.0	isoniazid
inhA	1673652	c.-550C>G	upstream_gene_variant	1.0	ethionamide
inhA	1673657	c.-545C>A	upstream_gene_variant	1.0	isoniazid
inhA	1673657	c.-545C>A	upstream_gene_variant	1.0	ethionamide
inhA	1673660	c.-542C>A	upstream_gene_variant	1.0	isoniazid
inhA	1673660	c.-542C>A	upstream_gene_variant	1.0	ethionamide
inhA	1673664	c.-538A>C	upstream_gene_variant	1.0	isoniazid
inhA	1673664	c.-538A>C	upstream_gene_variant	1.0	ethionamide
inhA	1673667	c.-535A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673667	c.-535A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673679	c.-523T>C	upstream_gene_variant	1.0	isoniazid	Uncertain significance
inhA	1673679	c.-523T>C	upstream_gene_variant	1.0	ethionamide	Uncertain significance
inhA	1673685	c.-517C>T	upstream_gene_variant	1.0	isoniazid
inhA	1673685	c.-517C>T	upstream_gene_variant	1.0	ethionamide
inhA	1673797	c.-405_-403delGCTinsACC	upstream_gene_variant	1.0	isoniazid
inhA	1673797	c.-405_-403delGCTinsACC	upstream_gene_variant	1.0	ethionamide
inhA	1673802	c.-400A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673802	c.-400A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673805	c.-397G>C	upstream_gene_variant	1.0	isoniazid
inhA	1673805	c.-397G>C	upstream_gene_variant	1.0	ethionamide
inhA	1673808	c.-394A>C	upstream_gene_variant	1.0	isoniazid
inhA	1673808	c.-394A>C	upstream_gene_variant	1.0	ethionamide
inhA	1673809	c.-393T>G	upstream_gene_variant	1.0	isoniazid
inhA	1673809	c.-393T>G	upstream_gene_variant	1.0	ethionamide
inhA	1673823	c.-378_-375delCGCA	upstream_gene_variant	0.92	isoniazid
inhA	1673823	c.-378_-375delCGCA	upstream_gene_variant	0.92	ethionamide
inhA	1673829	c.-373C>A	upstream_gene_variant	0.92	isoniazid
inhA	1673829	c.-373C>A	upstream_gene_variant	0.92	ethionamide
inhA	1673832	c.-370_-369insGCGG	upstream_gene_variant	0.86	isoniazid
inhA	1673832	c.-370_-369insGCGG	upstream_gene_variant	0.86	ethionamide
inhA	1673838	c.-364T>C	upstream_gene_variant	0.86	isoniazid
inhA	1673838	c.-364T>C	upstream_gene_variant	0.86	ethionamide
inhA	1673841	c.-361A>C	upstream_gene_variant	0.86	isoniazid
inhA	1673841	c.-361A>C	upstream_gene_variant	0.86	ethionamide
inhA	1673844	c.-358G>C	upstream_gene_variant	0.86	isoniazid
inhA	1673844	c.-358G>C	upstream_gene_variant	0.86	ethionamide
inhA	1673847	c.-355A>C	upstream_gene_variant	0.86	isoniazid
inhA	1673847	c.-355A>C	upstream_gene_variant	0.86	ethionamide
inhA	1673849	c.-353T>A	upstream_gene_variant	0.86	isoniazid
inhA	1673849	c.-353T>A	upstream_gene_variant	0.86	ethionamide
inhA	1673853	c.-349A>C	upstream_gene_variant	0.86	isoniazid
inhA	1673853	c.-349A>C	upstream_gene_variant	0.86	ethionamide
inhA	1673856	c.-346T>C	upstream_gene_variant	0.87	isoniazid
inhA	1673856	c.-346T>C	upstream_gene_variant	0.87	ethionamide
inhA	1673890	c.-312G>T	upstream_gene_variant	0.81	isoniazid
inhA	1673890	c.-312G>T	upstream_gene_variant	0.81	ethionamide
inhA	1673901	c.-301A>G	upstream_gene_variant	0.75	isoniazid
inhA	1673901	c.-301A>G	upstream_gene_variant	0.75	ethionamide
inhA	1673905	c.-297T>G	upstream_gene_variant	0.73	isoniazid
inhA	1673905	c.-297T>G	upstream_gene_variant	0.73	ethionamide
inhA	1673941	c.-261G>T	upstream_gene_variant	0.69	isoniazid
inhA	1673941	c.-261G>T	upstream_gene_variant	0.69	ethionamide
inhA	1673955	c.-247G>C	upstream_gene_variant	0.79	isoniazid
inhA	1673955	c.-247G>C	upstream_gene_variant	0.79	ethionamide
inhA	1673961	c.-241A>C	upstream_gene_variant	0.82	isoniazid
inhA	1673961	c.-241A>C	upstream_gene_variant	0.82	ethionamide
inhA	1673985	c.-217C>G	upstream_gene_variant	0.91	isoniazid
inhA	1673985	c.-217C>G	upstream_gene_variant	0.91	ethionamide
inhA	1674006	c.-196T>G	upstream_gene_variant	0.92	isoniazid
inhA	1674006	c.-196T>G	upstream_gene_variant	0.92	ethionamide
inhA	1674015	c.-187C>T	upstream_gene_variant	0.91	isoniazid	Uncertain significance
inhA	1674015	c.-187C>T	upstream_gene_variant	0.91	ethionamide
inhA	1674018	c.-184G>C	upstream_gene_variant	0.91	isoniazid
inhA	1674018	c.-184G>C	upstream_gene_variant	0.91	ethionamide
inhA	1674021	c.-181G>C	upstream_gene_variant	0.91	isoniazid
inhA	1674021	c.-181G>C	upstream_gene_variant	0.91	ethionamide
inhA	1674024	c.-178T>C	upstream_gene_variant	0.91	isoniazid
inhA	1674024	c.-178T>C	upstream_gene_variant	0.91	ethionamide
inhA	1674033	c.-169T>C	upstream_gene_variant	1.0	isoniazid
inhA	1674033	c.-169T>C	upstream_gene_variant	1.0	ethionamide
inhA	1674037	c.-165_-164delCAinsGC	upstream_gene_variant	1.0	isoniazid
inhA	1674037	c.-165_-164delCAinsGC	upstream_gene_variant	1.0	ethionamide
inhA	1674042	c.-160G>T	upstream_gene_variant	1.0	isoniazid
inhA	1674042	c.-160G>T	upstream_gene_variant	1.0	ethionamide
inhA	1674049	c.-153_-151delCAAinsGAC	upstream_gene_variant	1.0	isoniazid
inhA	1674049	c.-153_-151delCAAinsGAC	upstream_gene_variant	1.0	ethionamide
inhA	1674054	c.-148T>C	upstream_gene_variant	1.0	isoniazid
inhA	1674054	c.-148T>C	upstream_gene_variant	1.0	ethionamide
inhA	1674060	c.-142A>G	upstream_gene_variant	1.0	isoniazid
inhA	1674060	c.-142A>G	upstream_gene_variant	1.0	ethionamide
inhA	1674063	c.-139G>C	upstream_gene_variant	1.0	isoniazid
inhA	1674063	c.-139G>C	upstream_gene_variant	1.0	ethionamide
inhA	1674079	c.-123C>G	upstream_gene_variant	1.0	isoniazid
inhA	1674079	c.-123C>G	upstream_gene_variant	1.0	ethionamide
inhA	1674504	c.303C>G	synonymous_variant	0.92	isoniazid
inhA	1674504	c.303C>G	synonymous_variant	0.92	ethionamide
inhA	1674537	c.336C>G	synonymous_variant	0.96	isoniazid
inhA	1674537	c.336C>G	synonymous_variant	0.96	ethionamide
inhA	1674542	p.Ala114Glu	missense_variant	0.96	isoniazid
inhA	1674542	p.Ala114Glu	missense_variant	0.96	ethionamide
inhA	1674546	c.345T>C	synonymous_variant	0.96	isoniazid
inhA	1674546	c.345T>C	synonymous_variant	0.96	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	0.96	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	0.96	ethionamide
inhA	1674552	c.351C>G	synonymous_variant	0.96	isoniazid
inhA	1674552	c.351C>G	synonymous_variant	0.96	ethionamide
inhA	1674555	c.354G>A	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674555	c.354G>A	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674561	c.360C>T	synonymous_variant	1.0	isoniazid
inhA	1674561	c.360C>T	synonymous_variant	1.0	ethionamide
inhA	1674582	c.381T>C	synonymous_variant	1.0	isoniazid
inhA	1674582	c.381T>C	synonymous_variant	1.0	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	1.0	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	1.0	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	1.0	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	1.0	ethionamide
inhA	1674601	p.Leu134Thr	missense_variant	1.0	isoniazid
inhA	1674601	p.Leu134Thr	missense_variant	1.0	ethionamide
inhA	1674624	c.423A>C	synonymous_variant	1.0	isoniazid
inhA	1674624	c.423A>C	synonymous_variant	1.0	ethionamide
inhA	1674630	c.429C>G	synonymous_variant	1.0	isoniazid
inhA	1674630	c.429C>G	synonymous_variant	1.0	ethionamide
inhA	1674660	c.459G>C	synonymous_variant	1.0	isoniazid
inhA	1674660	c.459G>C	synonymous_variant	1.0	ethionamide
inhA	1674672	c.471C>G	synonymous_variant	1.0	isoniazid
inhA	1674672	c.471C>G	synonymous_variant	1.0	ethionamide
inhA	1674703	c.502T>C	synonymous_variant	1.0	isoniazid
inhA	1674703	c.502T>C	synonymous_variant	1.0	ethionamide
inhA	1674708	c.507G>A	synonymous_variant	1.0	isoniazid
inhA	1674708	c.507G>A	synonymous_variant	1.0	ethionamide
inhA	1674718	c.517A>C	synonymous_variant	1.0	isoniazid
inhA	1674718	c.517A>C	synonymous_variant	1.0	ethionamide
inhA	1674723	c.522C>T	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674723	c.522C>T	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674738	c.537C>G	synonymous_variant	1.0	isoniazid
inhA	1674738	c.537C>G	synonymous_variant	1.0	ethionamide
inhA	1674741	c.540C>T	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674741	c.540C>T	synonymous_variant	1.0	ethionamide
inhA	1674746	p.Tyr182Phe	missense_variant	1.0	isoniazid
inhA	1674746	p.Tyr182Phe	missense_variant	1.0	ethionamide
inhA	1674750	c.549T>C	synonymous_variant	1.0	isoniazid
inhA	1674750	c.549T>C	synonymous_variant	1.0	ethionamide
inhA	1674753	c.552G>C	synonymous_variant	1.0	isoniazid
inhA	1674753	c.552G>C	synonymous_variant	1.0	ethionamide
inhA	1674756	c.555T>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674756	c.555T>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674759	c.558G>C	synonymous_variant	1.0	isoniazid
inhA	1674759	c.558G>C	synonymous_variant	1.0	ethionamide
inhA	1674774	c.573A>G	synonymous_variant	1.0	isoniazid
inhA	1674774	c.573A>G	synonymous_variant	1.0	ethionamide
inhA	1674780	c.579T>G	synonymous_variant	1.0	isoniazid
inhA	1674780	c.579T>G	synonymous_variant	1.0	ethionamide
inhA	1674789	c.588G>C	synonymous_variant	1.0	isoniazid
inhA	1674789	c.588G>C	synonymous_variant	1.0	ethionamide
inhA	1674801	c.600T>C	synonymous_variant	1.0	isoniazid
inhA	1674801	c.600T>C	synonymous_variant	1.0	ethionamide
inhA	1674822	c.621C>G	synonymous_variant	1.0	isoniazid
inhA	1674822	c.621C>G	synonymous_variant	1.0	ethionamide
inhA	1674828	c.627G>A	synonymous_variant	1.0	isoniazid
inhA	1674828	c.627G>A	synonymous_variant	1.0	ethionamide
inhA	1674846	p.Ile215Met	missense_variant	0.97	isoniazid
inhA	1674846	p.Ile215Met	missense_variant	0.97	ethionamide
inhA	1674855	c.654C>G	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
inhA	1674855	c.654C>G	synonymous_variant	0.97	ethionamide
inhA	1674864	c.663C>T	synonymous_variant	0.96	isoniazid	Not assoc w R - Interim
inhA	1674864	c.663C>T	synonymous_variant	0.96	ethionamide	Not assoc w R - Interim
inhA	1674870	c.669T>C	synonymous_variant	0.92	isoniazid
inhA	1674870	c.669T>C	synonymous_variant	0.92	ethionamide
inhA	1674879	c.678T>C	synonymous_variant	0.92	isoniazid
inhA	1674879	c.678T>C	synonymous_variant	0.92	ethionamide
inhA	1674903	c.702T>C	synonymous_variant	0.92	isoniazid
inhA	1674903	c.702T>C	synonymous_variant	0.92	ethionamide
inhA	1674904	p.Ala235Pro	missense_variant	0.92	isoniazid
inhA	1674904	p.Ala235Pro	missense_variant	0.92	ethionamide
inhA	1674909	c.708G>A	synonymous_variant	0.91	isoniazid
inhA	1674909	c.708G>A	synonymous_variant	0.91	ethionamide
inhA	1674942	c.741T>G	synonymous_variant	0.89	isoniazid
inhA	1674942	c.741T>G	synonymous_variant	0.89	ethionamide
rpsA	1833554	p.Thr5Ala	missense_variant	1.0	pyrazinamide	Uncertain significance
rpsA	1833568	c.27G>C	synonymous_variant	0.95	pyrazinamide	Not assoc w R - Interim
rpsA	1833589	c.48A>T	synonymous_variant	0.92	pyrazinamide
rpsA	1833595	c.54T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1833661	c.120A>G	synonymous_variant	0.91	pyrazinamide
rpsA	1833667	c.126C>G	synonymous_variant	0.91	pyrazinamide
rpsA	1833721	c.180A>G	synonymous_variant	0.93	pyrazinamide
rpsA	1833724	c.183C>G	synonymous_variant	0.93	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	0.93	pyrazinamide
rpsA	1833742	c.201A>G	synonymous_variant	0.95	pyrazinamide
rpsA	1833745	c.204G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1833748	c.207C>G	synonymous_variant	0.98	pyrazinamide
rpsA	1833787	c.246C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833790	c.249T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833802	c.261A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833811	c.270G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833838	c.297G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833940	c.399C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833971	c.430C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834000	c.459G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834021	c.480C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834030	c.489C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834099	c.558C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	0.91	pyrazinamide
rpsA	1834105	c.564C>G	synonymous_variant	0.91	pyrazinamide
rpsA	1834108	c.567C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1834123	c.582C>G	synonymous_variant	0.94	pyrazinamide
rpsA	1834150	c.609G>C	synonymous_variant	0.9	pyrazinamide
rpsA	1834153	c.612T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834154	p.Asn205Gln	missense_variant	0.89	pyrazinamide
rpsA	1834157	c.616T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834162	c.621A>G	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
rpsA	1834165	c.624A>G	synonymous_variant	0.9	pyrazinamide
rpsA	1834169	p.Thr210Ala	missense_variant	0.91	pyrazinamide	Uncertain significance
rpsA	1834177	c.636A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834189	c.648G>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834195	c.654G>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834210	c.669C>T	synonymous_variant	0.94	pyrazinamide
rpsA	1834222	c.681T>C	synonymous_variant	0.92	pyrazinamide
rpsA	1834231	c.690T>C	synonymous_variant	0.96	pyrazinamide
rpsA	1834234	c.693G>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	0.94	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
rpsA	1834262	c.721_723delTCGinsAGC	synonymous_variant	1.0	pyrazinamide
rpsA	1834303	c.762T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834609	c.1068T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834633	c.1092A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834639	c.1098T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834654	p.Glu371Asp	missense_variant	1.0	pyrazinamide
rpsA	1834684	c.1143C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1834690	c.1149T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834732	c.1191T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834733	p.Ala398Ser	missense_variant	1.0	pyrazinamide
rpsA	1834738	c.1197A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834753	c.1212T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834765	p.Glu408Asp	missense_variant	1.0	pyrazinamide
rpsA	1834775	p.Ala412Thr	missense_variant	1.0	pyrazinamide
rpsA	1834780	c.1239A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834786	c.1245A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1834789	c.1248T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834792	c.1251G>C	synonymous_variant	1.0	pyrazinamide
bacA	2064892	c.-164A>G	upstream_gene_variant	0.8	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064897	c.-169C>G	upstream_gene_variant	0.82	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064903	c.-175G>A	upstream_gene_variant	0.83	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064912	c.-184A>G	upstream_gene_variant	0.86	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064915	c.-187G>C	upstream_gene_variant	0.86	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064933	c.-205A>G	upstream_gene_variant	0.9	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064936	c.-208C>G	upstream_gene_variant	0.9	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064942	c.-214G>A	upstream_gene_variant	0.9	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064948	c.-220G>C	upstream_gene_variant	0.91	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064972	c.-244T>C	upstream_gene_variant	0.96	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064978	c.-250G>C	upstream_gene_variant	0.96	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064979	c.-251C>T	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064984	c.-256A>G	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
bacA	2064993	c.-265T>C	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
kasA	2517950	c.-165C>G	upstream_gene_variant	1.0	isoniazid
kasA	2517989	c.-126T>C	upstream_gene_variant	1.0	isoniazid
kasA	2517993	c.-122G>T	upstream_gene_variant	1.0	isoniazid
kasA	2518768	c.654C>T	synonymous_variant	1.0	isoniazid
kasA	2518777	c.663C>T	synonymous_variant	1.0	isoniazid
kasA	2518783	c.669T>C	synonymous_variant	1.0	isoniazid
kasA	2518789	c.675G>C	synonymous_variant	1.0	isoniazid
kasA	2518792	c.678C>A	synonymous_variant	1.0	isoniazid
kasA	2518795	c.681C>G	synonymous_variant	1.0	isoniazid
kasA	2518825	c.711T>C	synonymous_variant	1.0	isoniazid
kasA	2519196	p.Thr361Ser	missense_variant	0.9	isoniazid
kasA	2519215	c.1101C>T	synonymous_variant	0.9	isoniazid
kasA	2519218	c.1104G>A	synonymous_variant	0.9	isoniazid
kasA	2519221	c.1107G>C	synonymous_variant	0.9	isoniazid
kasA	2519227	c.1113G>C	synonymous_variant	0.9	isoniazid
kasA	2519230	c.1116C>T	synonymous_variant	0.9	isoniazid
kasA	2519236	c.1122G>A	synonymous_variant	0.9	isoniazid
kasA	2519239	c.1125A>C	synonymous_variant	0.9	isoniazid
kasA	2519245	c.1131T>C	synonymous_variant	0.9	isoniazid
kasA	2519260	c.1146T>G	synonymous_variant	0.82	isoniazid
kasA	2519263	c.1149C>T	synonymous_variant	0.8	isoniazid
kasA	2519266	c.1152C>T	synonymous_variant	0.8	isoniazid
kasA	2519269	c.1155C>T	synonymous_variant	0.8	isoniazid
kasA	2519272	c.1158C>G	synonymous_variant	0.8	isoniazid
folC	2746321	c.1278A>G	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746328	p.Arg424Thr	missense_variant	1.0	para-aminosalicylic_acid
folC	2746335	p.Gly422Arg	missense_variant	1.0	para-aminosalicylic_acid
folC	2746336	c.1263C>G	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746345	c.1254G>C	synonymous_variant	0.92	para-aminosalicylic_acid
folC	2746351	p.Ala416Ser	missense_variant	0.92	para-aminosalicylic_acid
folC	2746354	c.1245G>A	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746363	p.Leu412Val	missense_variant	1.0	para-aminosalicylic_acid
folC	2746375	c.1224G>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746390	c.1209G>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746393	c.1206C>G	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746401	p.Ser400Ala	missense_variant	1.0	para-aminosalicylic_acid
folC	2746402	c.1197T>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746414	p.Glu395Gln	missense_variant	1.0	para-aminosalicylic_acid
folC	2746420	c.1179A>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746426	c.1173G>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746438	c.1161G>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746451	p.Gly383Ala	missense_variant	1.0	para-aminosalicylic_acid
folC	2746471	c.1128C>A	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2746478	p.Phe374Tyr	missense_variant	1.0	para-aminosalicylic_acid
folC	2746480	c.1119A>C	synonymous_variant	1.0	para-aminosalicylic_acid
folC	2747264	p.Gly112Ala	missense_variant	0.86	para-aminosalicylic_acid
folC	2747266	c.333C>T	synonymous_variant	0.86	para-aminosalicylic_acid
folC	2747275	c.324T>C	synonymous_variant	0.86	para-aminosalicylic_acid
folC	2747289	p.Pro104Ala	missense_variant	0.86	para-aminosalicylic_acid
folC	2747290	c.309A>G	synonymous_variant	0.86	para-aminosalicylic_acid
folC	2747293	c.306G>A	synonymous_variant	0.86	para-aminosalicylic_acid
folC	2747302	c.297A>G	synonymous_variant	0.87	para-aminosalicylic_acid
folC	2747314	c.285A>C	synonymous_variant	0.88	para-aminosalicylic_acid
folC	2747317	c.282C>G	synonymous_variant	0.88	para-aminosalicylic_acid
folC	2747343	p.Val86Ile	missense_variant	0.89	para-aminosalicylic_acid
folC	2747355	p.Val82Ile	missense_variant	0.89	para-aminosalicylic_acid
folC	2747359	c.240C>G	synonymous_variant	0.88	para-aminosalicylic_acid
folC	2747362	c.237G>C	synonymous_variant	0.88	para-aminosalicylic_acid
Rv2477c	2783194	c.849A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783221	c.822G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783224	c.819C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783230	c.813T>G	synonymous_variant	1.0	kanamycin
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2477c	2783235	c.808T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783254	c.789A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783263	c.780G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783275	c.768C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783278	c.765A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783293	c.750G>A	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783299	c.744A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783302	c.741A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783311	c.732T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783314	c.729C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2477c	2783317	c.726G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783332	c.711T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783335	c.708C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783350	c.693T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783353	c.690T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783359	c.684G>A	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783374	c.669G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783761	c.282G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783766	p.Met93Leu	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783776	c.267G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783779	c.264T>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783797	p.Asp82Glu	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783815	c.228A>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783821	p.Gln74Leu	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783833	c.210G>C	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783839	c.204C>G	synonymous_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783843	p.Gly67Asp	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783846	p.Thr66Asn	missense_variant	1.0	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783860	c.183T>C	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783863	c.180C>T	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783883	c.160T>C	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783884	c.159T>C	synonymous_variant	0.93	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783887	c.156C>G	synonymous_variant	0.94	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783914	c.129T>C	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783920	c.123G>C	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783929	c.114C>G	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783932	c.111C>T	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783938	c.105T>C	synonymous_variant	0.94	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783953	c.90G>A	synonymous_variant	0.93	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783962	c.81T>C	synonymous_variant	0.94	kanamycin	Not assoc w R - Interim
					levofloxacin
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783971	c.72G>C	synonymous_variant	0.93	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783980	c.63C>G	synonymous_variant	0.93	kanamycin
					levofloxacin
					moxifloxacin
					streptomycin
					rifampicin
					ethambutol
					amikacin
Rv2477c	2783992	c.51T>C	synonymous_variant	0.93	kanamycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					ethambutol	Not assoc w R - Interim
					amikacin
Rv2680	2996335	p.Glu77Asp	missense_variant	1.0	capreomycin
Rv2680	2996360	p.Met86Leu	missense_variant	1.0	capreomycin
Rv2681	2996368	c.-371T>C	upstream_gene_variant	1.0	capreomycin
mtrB	3626704	c.-91C>T	upstream_gene_variant	0.91	rifampicin
mtrB	3626704	c.-91C>T	upstream_gene_variant	0.91	bedaquiline
mtrB	3626711	c.-98T>C	upstream_gene_variant	0.92	rifampicin
mtrB	3626711	c.-98T>C	upstream_gene_variant	0.92	bedaquiline
mtrA	3626723	c.627C>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrA	3626723	c.627C>T	synonymous_variant	0.93	bedaquiline
mtrB	3626726	c.-113T>C	upstream_gene_variant	0.93	rifampicin
mtrB	3626726	c.-113T>C	upstream_gene_variant	0.93	bedaquiline
mtrB	3626729	c.-116G>A	upstream_gene_variant	0.93	rifampicin
mtrB	3626729	c.-116G>A	upstream_gene_variant	0.93	bedaquiline
mtrB	3626732	c.-119A>G	upstream_gene_variant	0.93	rifampicin
mtrB	3626732	c.-119A>G	upstream_gene_variant	0.93	bedaquiline
mtrA	3626759	c.591T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626759	c.591T>C	synonymous_variant	1.0	bedaquiline
mtrB	3626774	c.-163_-161delAGGinsCGC	upstream_gene_variant	1.0	rifampicin
mtrB	3626774	c.-163_-161delAGGinsCGC	upstream_gene_variant	1.0	bedaquiline
mtrB	3626783	c.-170C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3626783	c.-170C>G	upstream_gene_variant	1.0	bedaquiline
mtrA	3626786	c.564A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626786	c.564A>G	synonymous_variant	1.0	bedaquiline
mtrA	3626792	c.558G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626792	c.558G>T	synonymous_variant	1.0	bedaquiline
mtrB	3626795	c.-182C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3626795	c.-182C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3626798	c.-185T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3626798	c.-185T>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3626804	c.546A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3626804	c.546A>G	synonymous_variant	1.0	bedaquiline
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.9	rifampicin
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.9	bedaquiline
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.88	rifampicin
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.88	bedaquiline
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.89	rifampicin
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.89	bedaquiline
mtrB	3626987	c.-374C>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626987	c.-374C>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.96	rifampicin
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3627011	c.-398T>G	upstream_gene_variant	0.96	rifampicin
mtrB	3627011	c.-398T>G	upstream_gene_variant	0.96	bedaquiline
mtrB	3627065	c.-452G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627065	c.-452G>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627068	c.282T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627068	c.282T>C	synonymous_variant	1.0	bedaquiline
mtrA	3627071	c.279G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627071	c.279G>T	synonymous_variant	1.0	bedaquiline
mtrB	3627074	c.-461G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627074	c.-461G>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627080	c.270T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627080	c.270T>C	synonymous_variant	1.0	bedaquiline
mtrB	3627083	c.-470G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627083	c.-470G>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627098	c.252A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627098	c.252A>C	synonymous_variant	1.0	bedaquiline
mtrB	3627104	c.-491C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627104	c.-491C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627209	c.-596G>A	upstream_gene_variant	1.0	rifampicin
mtrB	3627209	c.-596G>A	upstream_gene_variant	1.0	bedaquiline
mtrA	3627221	c.129C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627221	c.129C>T	synonymous_variant	1.0	bedaquiline
mtrA	3627227	c.123T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627227	c.123T>C	synonymous_variant	1.0	bedaquiline
mtrB	3627233	c.-620T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627233	c.-620T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627236	c.-623T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627236	c.-623T>C	upstream_gene_variant	1.0	bedaquiline
mtrA	3627242	c.108C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrA	3627242	c.108C>T	synonymous_variant	1.0	bedaquiline
mtrB	3627254	c.-641C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627254	c.-641C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627263	c.-650C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627263	c.-650C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627266	c.-653A>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627266	c.-653A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627272	c.-659G>T	upstream_gene_variant	0.92	rifampicin
mtrB	3627272	c.-659G>T	upstream_gene_variant	0.92	bedaquiline
mtrB	3627275	c.-662G>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627275	c.-662G>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627296	c.-683T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627296	c.-683T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627299	c.-688_-686delTTGinsCTA	upstream_gene_variant	1.0	rifampicin
mtrB	3627299	c.-688_-686delTTGinsCTA	upstream_gene_variant	1.0	bedaquiline
fbiB	3641864	c.330A>C	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiB	3641876	c.342C>G	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiB	3641879	c.345G>C	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiB	3641880	p.Ser116Asp	missense_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiB	3641888	c.354A>G	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiB	3641891	c.357G>C	synonymous_variant	0.75	pretomanid
					delamanid
					clofazimine
fbiB	3641900	c.366G>C	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641906	c.372T>C	synonymous_variant	0.9	pretomanid
					delamanid
					clofazimine
fbiB	3641909	c.375T>G	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641914	p.Ala127Gly	missense_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641918	c.384T>C	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641924	c.390A>C	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641927	c.393C>G	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641928	c.394T>C	synonymous_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641938	p.Gly135Ala	missense_variant	0.82	pretomanid
					delamanid
					clofazimine
fbiB	3641961	p.Thr143Glu	missense_variant	0.8	pretomanid
					delamanid
					clofazimine
fbiB	3642656	c.1122G>C	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiB	3642659	c.1125C>G	synonymous_variant	0.89	pretomanid
					delamanid
					clofazimine
fbiB	3642668	c.1134A>G	synonymous_variant	0.89	pretomanid
					delamanid
					clofazimine
fbiB	3642677	c.1143A>G	synonymous_variant	0.9	pretomanid
					delamanid
					clofazimine
fbiB	3642680	c.1146A>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiB	3642684	c.1150T>C	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiB	3642701	c.1167C>G	synonymous_variant	0.95	pretomanid
					delamanid
					clofazimine
fbiB	3642719	c.1185T>C	synonymous_variant	0.89	pretomanid
					delamanid
					clofazimine
fbiB	3642731	c.1197C>G	synonymous_variant	0.88	pretomanid
					delamanid
					clofazimine
fbiB	3642743	c.1209T>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiB	3642749	c.1215T>C	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiB	3642758	c.1224C>G	synonymous_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiB	3642763	p.Asp410Ala	missense_variant	0.94	pretomanid
					delamanid
					clofazimine
fbiB	3642770	c.1236G>C	synonymous_variant	0.93	pretomanid
					delamanid
					clofazimine
fbiB	3642779	c.1245A>C	synonymous_variant	0.92	pretomanid
					delamanid
					clofazimine
fbiB	3642781	p.Val416Ala	missense_variant	0.92	pretomanid
					delamanid
					clofazimine
rpoA	3877503	c.1005G>C	synonymous_variant	1.0	rifampicin
rpoA	3877507	p.Gly334Ala	missense_variant	1.0	rifampicin
rpoA	3877515	c.993G>C	synonymous_variant	1.0	rifampicin
rpoA	3877553	p.Glu319Gln	missense_variant	1.0	rifampicin
rpoA	3877571	p.Pro313Ala	missense_variant	1.0	rifampicin
rpoA	3877587	c.921A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877613	p.Ile299Val	missense_variant	1.0	rifampicin
rpoA	3877656	c.852T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877668	c.840A>G	synonymous_variant	1.0	rifampicin
rpoA	3877679	p.Ala277Ser	missense_variant	1.0	rifampicin
rpoA	3877686	c.822A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877692	c.816G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877704	c.804G>C	synonymous_variant	1.0	rifampicin
rpoA	3877743	c.765T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877764	c.744C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877770	c.738A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877776	c.732T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877782	c.726T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877791	c.717C>G	synonymous_variant	1.0	rifampicin
rpoA	3877818	c.690A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877839	c.669G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877848	c.660C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877857	c.651G>A	synonymous_variant	1.0	rifampicin
rpoA	3877866	c.642G>C	synonymous_variant	1.0	rifampicin
rpoA	3877875	c.633T>G	synonymous_variant	1.0	rifampicin
rpoA	3877878	c.630G>C	synonymous_variant	1.0	rifampicin
rpoA	3877890	c.618C>T	synonymous_variant	1.0	rifampicin
rpoA	3877896	c.612G>C	synonymous_variant	1.0	rifampicin
rpoA	3877900	p.Ser203Asn	missense_variant	1.0	rifampicin
rpoA	3877905	c.603A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877909	p.Asn200Ser	missense_variant	1.0	rifampicin
rpoA	3877920	c.588G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877923	c.585C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877926	c.582G>C	synonymous_variant	0.97	rifampicin
rpoA	3877962	c.546G>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3877986	c.522G>C	synonymous_variant	0.97	rifampicin
rpoA	3877989	c.519A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3878001	c.507A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3878022	c.486T>C	synonymous_variant	0.93	rifampicin
rpoA	3878028	c.480G>C	synonymous_variant	0.93	rifampicin
rpoA	3878031	c.477T>C	synonymous_variant	0.93	rifampicin
rpoA	3878040	c.468T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoA	3878043	c.465G>A	synonymous_variant	0.92	rifampicin
rpoA	3878055	c.453A>G	synonymous_variant	0.89	rifampicin
rpoA	3878058	c.450G>T	synonymous_variant	0.89	rifampicin
rpoA	3878061	c.447G>C	synonymous_variant	0.89	rifampicin
rpoA	3878067	c.441C>G	synonymous_variant	0.89	rifampicin
rpoA	3878070	c.438T>C	synonymous_variant	0.94	rifampicin
rpoA	3878076	c.432C>T	synonymous_variant	0.95	rifampicin
rpoA	3878082	c.426T>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878094	c.414C>G	synonymous_variant	0.94	rifampicin
rpoA	3878103	c.405A>G	synonymous_variant	0.95	rifampicin
rpoA	3878106	c.402G>C	synonymous_variant	0.95	rifampicin
rpoA	3878118	c.390T>C	synonymous_variant	0.94	rifampicin
rpoA	3878130	c.378C>G	synonymous_variant	0.94	rifampicin
rpoA	3878141	p.Met123Leu	missense_variant	0.95	rifampicin	Uncertain significance
rpoA	3878143	p.Gly122Asp	missense_variant	0.95	rifampicin	Uncertain significance
rpoA	3878157	c.351C>G	synonymous_variant	0.96	rifampicin
rpoA	3878163	c.345C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoA	3878169	c.339G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoA	3878172	c.336G>C	synonymous_variant	1.0	rifampicin
rpoA	3878181	c.327C>T	synonymous_variant	1.0	rifampicin
rpoA	3878187	c.321C>G	synonymous_variant	1.0	rifampicin
rpoA	3878193	c.315T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878199	c.309T>C	synonymous_variant	1.0	rifampicin
rpoA	3878217	c.291A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878226	c.282C>G	synonymous_variant	1.0	rifampicin
rpoA	3878232	c.276G>C	synonymous_variant	1.0	rifampicin
rpoA	3878247	c.261G>C	synonymous_variant	1.0	rifampicin
rpoA	3878271	c.237T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878284	p.Glu75Ala	missense_variant	1.0	rifampicin
rpoA	3878292	c.216T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878298	c.210A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878304	c.204G>C	synonymous_variant	1.0	rifampicin
rpoA	3878313	c.195G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878322	c.186A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878331	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878334	c.174T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878337	c.171T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878340	c.168C>T	synonymous_variant	1.0	rifampicin
rpoA	3878346	c.162T>C	synonymous_variant	1.0	rifampicin
rpoA	3878364	c.144A>T	synonymous_variant	1.0	rifampicin
rpoA	3878367	c.141C>G	synonymous_variant	1.0	rifampicin
rpoA	3878376	c.132G>C	synonymous_variant	1.0	rifampicin
rpoA	3878385	c.123C>G	synonymous_variant	1.0	rifampicin
rpoA	3878388	c.120C>G	synonymous_variant	1.0	rifampicin
rpoA	3878391	c.117T>C	synonymous_variant	1.0	rifampicin
rpoA	3878415	c.93C>T	synonymous_variant	0.98	rifampicin
rpoA	3878424	c.84G>C	synonymous_variant	0.98	rifampicin
rpoA	3878436	c.72A>G	synonymous_variant	0.98	rifampicin
rpoA	3878442	c.66G>C	synonymous_variant	0.97	rifampicin
rpoA	3878454	c.54A>C	synonymous_variant	0.97	rifampicin
rpoA	3878472	p.Asp12Glu	missense_variant	0.95	rifampicin
rpoA	3878478	c.30C>G	synonymous_variant	0.95	rifampicin
rpoA	3878484	c.24C>A	synonymous_variant	0.95	rifampicin
rpoA	3878490	c.18C>A	synonymous_variant	0.95	rifampicin
rpoA	3878496	c.12A>T	synonymous_variant	0.94	rifampicin
rpoA	3878713	c.-206G>A	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878716	c.-209C>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878725	c.-218A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878736	c.-229A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878737	c.-230G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878742	c.-235G>A	upstream_gene_variant	1.0	rifampicin
rpoA	3878746	c.-239A>G	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878749	c.-242G>T	upstream_gene_variant	1.0	rifampicin
rpoA	3878761	c.-254G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878764	c.-257A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878785	c.-278T>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878788	c.-281G>C	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878806	c.-299C>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878809	c.-302T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878824	c.-317G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878833	c.-326C>G	upstream_gene_variant	0.97	rifampicin
rpoA	3878836	c.-331_-329delAAGinsTCC	upstream_gene_variant	0.96	rifampicin
rpoA	3878853	c.-346G>A	upstream_gene_variant	0.97	rifampicin
rpoA	3878860	c.-353C>T	upstream_gene_variant	0.93	rifampicin
rpoA	3878878	c.-371T>C	upstream_gene_variant	0.9	rifampicin	Uncertain significance
rpoA	3878909	c.-402A>G	upstream_gene_variant	0.88	rifampicin
rpoA	3878914	c.-407T>C	upstream_gene_variant	0.88	rifampicin	Uncertain significance
rpoA	3878917	c.-410G>A	upstream_gene_variant	0.88	rifampicin	Uncertain significance
rpoA	3878938	c.-431T>A	upstream_gene_variant	0.87	rifampicin
rpoA	3878947	c.-440G>C	upstream_gene_variant	0.86	rifampicin	Uncertain significance
rpoA	3878962	c.-455G>A	upstream_gene_variant	0.86	rifampicin	Uncertain significance
rpoA	3878968	c.-461T>C	upstream_gene_variant	0.85	rifampicin	Uncertain significance
rpoA	3878976	c.-469A>G	upstream_gene_variant	0.86	rifampicin	Uncertain significance
rpoA	3878986	c.-479G>C	upstream_gene_variant	0.89	rifampicin
rpoA	3878998	c.-491C>G	upstream_gene_variant	0.89	rifampicin	Uncertain significance
rpoA	3879005	c.-499_-498delAAinsCG	upstream_gene_variant	0.89	rifampicin
rpoA	3879013	c.-506A>G	upstream_gene_variant	0.93	rifampicin
rpoA	3879079	c.-572A>G	upstream_gene_variant	0.96	rifampicin
rpoA	3879088	c.-581A>C	upstream_gene_variant	0.96	rifampicin
rpoA	3879094	c.-587T>C	upstream_gene_variant	0.98	rifampicin
rpoA	3879121	c.-614T>G	upstream_gene_variant	0.98	rifampicin
rpoA	3879127	c.-620T>C	upstream_gene_variant	0.97	rifampicin
rpoA	3879154	c.-647T>C	upstream_gene_variant	0.93	rifampicin
rpoA	3879160	c.-653A>G	upstream_gene_variant	0.93	rifampicin
rpoA	3879178	c.-671T>C	upstream_gene_variant	0.96	rifampicin
rpoA	3879190	c.-683C>G	upstream_gene_variant	0.95	rifampicin
rpoA	3879222	c.-715T>C	upstream_gene_variant	0.86	rifampicin
rpoA	3879226	c.-719G>C	upstream_gene_variant	0.86	rifampicin
rpoA	3879229	c.-722A>G	upstream_gene_variant	0.86	rifampicin
rpoA	3879232	c.-725A>G	upstream_gene_variant	0.86	rifampicin
clpC1	4038239	c.2466T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4038255	p.Val817Lys	missense_variant	0.94	pyrazinamide
clpC1	4038271	p.Pro812Ala	missense_variant	1.0	pyrazinamide
clpC1	4038272	p.Gly811Ser	missense_variant	1.0	pyrazinamide
clpC1	4038275	c.2430A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038278	c.2427T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038293	c.2412G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038302	c.2403C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038308	c.2397G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038314	c.2391T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038317	c.2388G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038320	c.2385G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038356	c.2349T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038359	c.2346A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4038368	c.2337T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038386	c.2317_2319delTTGinsCTC	synonymous_variant	0.95	pyrazinamide
clpC1	4038392	c.2313C>T	synonymous_variant	0.95	pyrazinamide
clpC1	4038398	c.2307G>T	synonymous_variant	0.95	pyrazinamide
clpC1	4038403	c.2302T>C	synonymous_variant	0.96	pyrazinamide	Not assoc w R - Interim
clpC1	4038407	c.2298G>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038419	c.2286T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038433	c.2272C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4038434	c.2271G>A	synonymous_variant	0.97	pyrazinamide
clpC1	4038444	p.Ala754Lys	missense_variant	0.96	pyrazinamide
clpC1	4038446	c.2259T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038456	p.Val750Glu	missense_variant	0.97	pyrazinamide
clpC1	4038460	p.Leu749Met	missense_variant	0.97	pyrazinamide
clpC1	4038486	p.Gly740Asn	missense_variant	0.97	pyrazinamide
clpC1	4038489	p.Ala739Gly	missense_variant	0.97	pyrazinamide
clpC1	4038494	c.2211G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038497	p.Ser736Gln	missense_variant	0.97	pyrazinamide
clpC1	4038509	c.2196C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038530	p.Glu725Asp	missense_variant	1.0	pyrazinamide
clpC1	4038596	c.2109A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038623	c.2082A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038640	p.Asp689Asn	missense_variant	1.0	pyrazinamide
clpC1	4038653	c.2052C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038658	p.Lys683Gln	missense_variant	1.0	pyrazinamide
clpC1	4038661	p.Ser682Thr	missense_variant	1.0	pyrazinamide
clpC1	4038662	c.2043T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038671	c.2034T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038683	c.2022T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038695	c.2010C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038701	c.2004G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038704	c.2001T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038707	c.1998C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038710	c.1995G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038713	c.1992T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038749	c.1956C>A	synonymous_variant	0.94	pyrazinamide
clpC1	4038755	c.1950G>T	synonymous_variant	0.94	pyrazinamide
clpC1	4038770	c.1935C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4038773	c.1932T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4038782	c.1923G>C	synonymous_variant	0.93	pyrazinamide
clpC1	4038812	c.1893T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4038845	c.1860G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4038860	c.1845G>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4038878	c.1827A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038893	c.1812C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038908	c.1797C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038914	c.1791G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038923	c.1780_1782delCTAinsTTG	synonymous_variant	1.0	pyrazinamide
clpC1	4038953	c.1752A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038956	c.1749T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038965	c.1740T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038971	c.1734T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038974	c.1731T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038989	c.1716T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4038997	c.1708T>C	synonymous_variant	0.95	pyrazinamide	Not assoc w R - Interim
clpC1	4039004	c.1701C>G	synonymous_variant	0.96	pyrazinamide
clpC1	4039022	c.1683A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4039064	c.1641C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4039097	c.1608G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039103	c.1602T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039106	c.1599G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039112	c.1593C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039121	c.1584T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039142	c.1563A>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039145	c.1560G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039169	p.Glu512Asp	missense_variant	0.95	pyrazinamide
clpC1	4039172	c.1533A>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039178	c.1527G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039183	c.1522T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039186	c.1519C>T	synonymous_variant	0.94	pyrazinamide
clpC1	4039190	c.1515C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039226	c.1479T>C	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
clpC1	4039229	c.1476C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039274	c.1431G>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4039286	c.1419T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039295	c.1410A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039298	c.1407T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039319	c.1386T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039322	c.1383T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039328	c.1377A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039331	c.1374C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039337	p.Thr456Gln	missense_variant	1.0	pyrazinamide
clpC1	4039349	c.1356C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4039352	c.1353C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4039364	c.1341C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4039391	c.1314T>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039409	c.1296T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039412	c.1293T>G	synonymous_variant	0.93	pyrazinamide
clpC1	4039415	p.Glu430Asp	missense_variant	0.93	pyrazinamide	Uncertain significance
clpC1	4039430	c.1275T>C	synonymous_variant	0.92	pyrazinamide
clpC1	4039481	c.1224T>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039484	c.1221T>C	synonymous_variant	0.85	pyrazinamide
clpC1	4039517	c.1188C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039556	c.1149G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039559	c.1146C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039562	c.1143C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039565	c.1140G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039570	p.Met379Leu	missense_variant	0.95	pyrazinamide	Uncertain significance
clpC1	4039576	p.Ala377Pro	missense_variant	0.95	pyrazinamide
clpC1	4039577	c.1128T>C	synonymous_variant	0.95	pyrazinamide	Not assoc w R - Interim
clpC1	4039589	c.1116G>C	synonymous_variant	0.96	pyrazinamide
clpC1	4039610	c.1095G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039616	c.1089G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039928	c.775_777delAGCinsTCG	synonymous_variant	1.0	pyrazinamide
clpC1	4039931	c.774T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039937	c.768G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039946	c.759A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039952	c.753T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4039982	c.723G>A	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4039988	c.717C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4039991	c.714G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040021	c.684A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040024	c.681A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040033	c.672G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040036	c.669C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040090	c.613_615delTCTinsAGC	synonymous_variant	1.0	pyrazinamide
clpC1	4040093	c.612C>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040105	c.600C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040147	c.558A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040162	c.543G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040165	c.540G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040171	c.534C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040201	c.504C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040207	c.498T>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040210	c.495G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040213	c.490_492delTCTinsAGC	synonymous_variant	1.0	pyrazinamide
clpC1	4040225	c.480A>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040228	c.477G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4040237	c.468C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4040246	c.459C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040249	c.456A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040267	c.438A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040273	c.432T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040276	c.427_429delTCCinsAGT	synonymous_variant	1.0	pyrazinamide
clpC1	4040279	c.426C>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040291	c.414G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040318	c.387C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040330	c.375C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040342	c.363C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040354	c.351A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040363	c.342A>T	synonymous_variant	1.0	pyrazinamide
clpC1	4040369	c.336C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040380	c.325T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040381	c.324T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040387	c.318A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040393	c.312G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040411	c.294T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040423	c.282A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040426	c.279T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040431	c.274T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040444	c.261C>T	synonymous_variant	1.0	pyrazinamide
clpC1	4040450	c.255A>G	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040459	c.246C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040465	c.240T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040471	c.234T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040477	c.228G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040480	c.225T>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040522	c.183T>C	synonymous_variant	0.91	pyrazinamide	Not assoc w R - Interim
clpC1	4040528	c.177G>T	synonymous_variant	0.95	pyrazinamide
clpC1	4040531	c.174T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4040534	c.171A>G	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
clpC1	4040537	c.168G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4040546	c.159G>C	synonymous_variant	0.89	pyrazinamide
clpC1	4040551	c.154T>C	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
clpC1	4040561	c.144A>G	synonymous_variant	0.85	pyrazinamide
clpC1	4040567	c.138C>G	synonymous_variant	0.82	pyrazinamide
panD	4044737	c.-456T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044746	c.-467_-465delGTGinsATC	upstream_gene_variant	1.0	pyrazinamide
panD	4044752	c.-471T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044779	c.-500_-498delCTAinsTGC	upstream_gene_variant	1.0	pyrazinamide
panD	4044788	c.-507G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044791	c.-510G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044800	c.-519C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044812	c.-531A>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044818	c.-538_-537delCGinsAC	upstream_gene_variant	1.0	pyrazinamide
panD	4044823	c.-542G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044833	c.-552A>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044844	c.-563T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044848	c.-567T>A	upstream_gene_variant	1.0	pyrazinamide
panD	4044854	c.-573A>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044860	c.-579C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044872	c.-591C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044890	c.-609G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044895	c.-614A>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044896	c.-615T>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044902	c.-623_-621delACGinsGCC	upstream_gene_variant	1.0	pyrazinamide
panD	4044908	c.-628_-627delCTinsTC	upstream_gene_variant	1.0	pyrazinamide
panD	4044917	c.-636G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044926	c.-645C>A	upstream_gene_variant	1.0	pyrazinamide
panD	4044929	c.-648G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044935	c.-655_-654delAAinsTG	upstream_gene_variant	1.0	pyrazinamide
panD	4044941	c.-660G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4044954	c.-674_-673delCCinsAT	upstream_gene_variant	1.0	pyrazinamide
panD	4044980	c.-699A>G	upstream_gene_variant	1.0	pyrazinamide
panD	4044983	c.-702G>T	upstream_gene_variant	1.0	pyrazinamide
panD	4044989	c.-708T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045000	c.-719A>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045001	c.-720G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045019	c.-738G>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045022	c.-741C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4045028	c.-747C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4045034	c.-753A>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045055	c.-774T>G	upstream_gene_variant	1.0	pyrazinamide
panD	4045067	c.-786C>G	upstream_gene_variant	1.0	pyrazinamide
panD	4045070	c.-789C>T	upstream_gene_variant	1.0	pyrazinamide
panD	4045076	c.-795A>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045088	c.-807T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045094	c.-813T>C	upstream_gene_variant	1.0	pyrazinamide
panD	4045097	c.-816T>C	upstream_gene_variant	1.0	pyrazinamide
embC	4240726	c.864G>C	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embC	4240780	c.918T>C	synonymous_variant	0.95	ethambutol
embC	4240783	c.921G>C	synonymous_variant	0.95	ethambutol
embC	4240789	c.927T>C	synonymous_variant	0.95	ethambutol
embC	4240819	c.957A>G	synonymous_variant	0.96	ethambutol
embC	4240828	c.966G>A	synonymous_variant	0.95	ethambutol
embC	4240831	c.969T>G	synonymous_variant	0.95	ethambutol
embC	4240867	c.1005T>C	synonymous_variant	0.92	ethambutol
embC	4240870	c.1008T>C	synonymous_variant	0.92	ethambutol
embC	4240873	c.1011C>G	synonymous_variant	0.91	ethambutol
embC	4240879	c.1017G>C	synonymous_variant	0.91	ethambutol
embC	4240880	p.Ala340Thr	missense_variant	0.91	ethambutol	Uncertain significance
embC	4240885	c.1023T>C	synonymous_variant	0.91	ethambutol
embB	4245659	c.-855C>G	upstream_gene_variant	0.8	ethambutol
embA	4245674	c.2442A>C	synonymous_variant	0.82	ethambutol	Not assoc w R - Interim
embB	4245677	c.-837G>C	upstream_gene_variant	0.82	ethambutol
embA	4245693	p.Ile821Val	missense_variant	0.9	ethambutol
embB	4245737	c.-777A>C	upstream_gene_variant	1.0	ethambutol
embB	4245740	c.-774T>C	upstream_gene_variant	1.0	ethambutol
embB	4245764	c.-750G>C	upstream_gene_variant	1.0	ethambutol
embA	4245772	p.Asn847Thr	missense_variant	1.0	ethambutol
embA	4245785	c.2553G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4245807	c.-707_-705delTTAinsCTG	upstream_gene_variant	1.0	ethambutol
embB	4245812	c.-702G>C	upstream_gene_variant	1.0	ethambutol
embA	4245813	p.Pro861Ala	missense_variant	1.0	ethambutol
embA	4245820	p.Ser863Thr	missense_variant	1.0	ethambutol
embB	4245824	c.-690G>C	upstream_gene_variant	1.0	ethambutol
embB	4245833	c.-681G>C	upstream_gene_variant	1.0	ethambutol
embB	4245842	c.-672G>C	upstream_gene_variant	1.0	ethambutol
embB	4245845	c.-669T>C	upstream_gene_variant	1.0	ethambutol
embB	4245851	c.-663G>C	upstream_gene_variant	1.0	ethambutol
embB	4245860	c.-654C>G	upstream_gene_variant	1.0	ethambutol
embB	4246064	c.-450T>C	upstream_gene_variant	0.85	ethambutol
embA	4246080	p.Pro950Ser	missense_variant	0.88	ethambutol
embA	4246088	c.2856A>G	synonymous_variant	0.91	ethambutol	Not assoc w R
embB	4246097	c.-417C>G	upstream_gene_variant	0.92	ethambutol
embA	4246103	c.2871C>G	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
embB	4246109	c.-405C>G	upstream_gene_variant	0.92	ethambutol
embB	4246115	c.-399T>G	upstream_gene_variant	0.91	ethambutol
embA	4246128	p.Ser966Thr	missense_variant	0.91	ethambutol
embA	4246138	p.Arg969Gln	missense_variant	0.95	ethambutol
embB	4246140	c.-374T>C	upstream_gene_variant	0.95	ethambutol
embA	4246143	p.Ile971Val	missense_variant	0.95	ethambutol
embA	4246151	c.2919A>G	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embA	4246152	p.Ala974Gln	missense_variant	0.95	ethambutol
embB	4246157	c.-357A>G	upstream_gene_variant	0.95	ethambutol
embA	4246164	c.2932T>C	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embB	4246184	c.-330A>C	upstream_gene_variant	0.96	ethambutol
embB	4246196	c.-318C>G	upstream_gene_variant	0.96	ethambutol
embB	4246205	c.-309A>G	upstream_gene_variant	0.96	ethambutol
embB	4246211	c.-303T>C	upstream_gene_variant	1.0	ethambutol
embB	4246217	c.-297G>A	upstream_gene_variant	1.0	ethambutol
embA	4246220	c.2988T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4246223	c.-291C>T	upstream_gene_variant	1.0	ethambutol
embA	4246227	p.Ile999Val	missense_variant	1.0	ethambutol
embA	4246235	c.3003G>A	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embA	4246242	p.Gln1004Gly	missense_variant	1.0	ethambutol
embB	4246250	c.-264G>C	upstream_gene_variant	1.0	ethambutol
embB	4246256	c.-258G>T	upstream_gene_variant	1.0	ethambutol
embB	4246259	c.-255G>C	upstream_gene_variant	1.0	ethambutol
embA	4246264	p.His1011Arg	missense_variant	1.0	ethambutol
embB	4246292	c.-222A>G	upstream_gene_variant	1.0	ethambutol
embA	4246305	p.Ser1025Glu	missense_variant	1.0	ethambutol
embA	4246308	p.Thr1026Ala	missense_variant	1.0	ethambutol
embB	4246316	c.-198T>G	upstream_gene_variant	1.0	ethambutol
embB	4246319	c.-195G>C	upstream_gene_variant	0.96	ethambutol
embA	4246329	p.Thr1033Ala	missense_variant	1.0	ethambutol
embB	4246349	c.-165C>G	upstream_gene_variant	1.0	ethambutol
embA	4246359	p.Ala1043Ser	missense_variant	1.0	ethambutol
embB	4246367	c.-147C>T	upstream_gene_variant	1.0	ethambutol
embB	4246373	c.-141T>C	upstream_gene_variant	1.0	ethambutol
embB	4246376	c.-138G>C	upstream_gene_variant	1.0	ethambutol
embA	4246379	c.3147C>T	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247375	p.Leu288Val	missense_variant	1.0	ethambutol
embB	4247386	c.873T>C	synonymous_variant	1.0	ethambutol
embB	4247389	c.876C>G	synonymous_variant	1.0	ethambutol
embB	4247395	c.882C>G	synonymous_variant	1.0	ethambutol
embB	4247401	c.888T>C	synonymous_variant	1.0	ethambutol
embB	4247407	c.894G>C	synonymous_variant	1.0	ethambutol
embB	4247425	c.912G>C	synonymous_variant	1.0	ethambutol
embB	4247434	c.921C>G	synonymous_variant	1.0	ethambutol
embB	4247437	c.924A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247440	c.927C>G	synonymous_variant	1.0	ethambutol
embB	4247446	c.933C>T	synonymous_variant	1.0	ethambutol
embB	4247464	c.951C>G	synonymous_variant	1.0	ethambutol
embB	4247470	c.957T>C	synonymous_variant	1.0	ethambutol
embB	4247491	c.978G>C	synonymous_variant	1.0	ethambutol
embB	4247497	c.984T>C	synonymous_variant	1.0	ethambutol
embB	4247512	c.999T>C	synonymous_variant	1.0	ethambutol
embB	4247539	c.1026T>C	synonymous_variant	1.0	ethambutol
embB	4247554	c.1041T>C	synonymous_variant	1.0	ethambutol
embB	4247566	c.1053C>A	synonymous_variant	1.0	ethambutol
embB	4247572	c.1059A>G	synonymous_variant	1.0	ethambutol
embB	4247579	p.Ala356Phe	missense_variant	1.0	ethambutol
embB	4247587	c.1074G>A	synonymous_variant	1.0	ethambutol
embB	4247603	c.1090C>T	synonymous_variant	1.0	ethambutol
embB	4247611	c.1098G>T	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247614	c.1101T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4247629	c.1116C>G	synonymous_variant	0.95	ethambutol
embB	4247632	c.1119C>G	synonymous_variant	0.95	ethambutol
embB	4247638	c.1125G>T	synonymous_variant	0.94	ethambutol
embB	4247646	p.Glu378Ala	missense_variant	0.92	ethambutol	Not assoc w R
embB	4247656	c.1143A>G	synonymous_variant	0.91	ethambutol
embB	4247659	c.1146C>G	synonymous_variant	0.91	ethambutol
embB	4247683	c.1170C>G	synonymous_variant	0.85	ethambutol
embB	4247692	c.1179C>G	synonymous_variant	0.88	ethambutol
embB	4247716	c.1203C>T	synonymous_variant	0.89	ethambutol
embB	4247722	c.1209G>C	synonymous_variant	0.89	ethambutol
embB	4247725	c.1212G>C	synonymous_variant	0.89	ethambutol
embB	4247729	p.Gly406Pro	missense_variant	0.89	ethambutol
embB	4247746	c.1233C>T	synonymous_variant	0.9	ethambutol
embB	4247761	c.1248T>C	synonymous_variant	0.92	ethambutol
embB	4247773	c.1260G>A	synonymous_variant	0.96	ethambutol
embB	4247776	c.1263G>T	synonymous_variant	0.96	ethambutol
embB	4247797	c.1284C>G	synonymous_variant	0.94	ethambutol
embB	4247800	c.1287A>T	synonymous_variant	0.94	ethambutol
embB	4247803	c.1290G>C	synonymous_variant	0.94	ethambutol
embB	4247815	c.1302C>G	synonymous_variant	0.92	ethambutol
embB	4247819	p.Val436Ile	missense_variant	0.94	ethambutol	Uncertain significance
embB	4247830	c.1317A>G	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embB	4247836	c.1323A>G	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embB	4247839	c.1326G>C	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embB	4247866	c.1353G>C	synonymous_variant	0.94	ethambutol
embB	4247875	c.1362G>C	synonymous_variant	0.94	ethambutol
embB	4247876	c.1363C>T	synonymous_variant	0.94	ethambutol
embB	4247881	c.1368G>C	synonymous_variant	0.94	ethambutol
embB	4247887	c.1374C>T	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embB	4247893	c.1380C>T	synonymous_variant	0.93	ethambutol
embB	4247899	p.Met462Ile	missense_variant	0.93	ethambutol
embB	4247905	c.1392G>C	synonymous_variant	0.93	ethambutol	Not assoc w R - Interim
embB	4247909	c.1396T>C	synonymous_variant	0.92	ethambutol
embB	4247914	c.1401G>C	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
embB	4247932	c.1419C>G	synonymous_variant	0.95	ethambutol
embB	4247940	p.Leu476Trp	missense_variant	0.95	ethambutol
embB	4247945	c.1432T>C	synonymous_variant	0.95	ethambutol
embB	4247951	p.Ser480Ala	missense_variant	0.95	ethambutol
embB	4247956	c.1443G>C	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
embB	4247974	c.1461C>G	synonymous_variant	1.0	ethambutol
embB	4248007	c.1494C>G	synonymous_variant	1.0	ethambutol
embB	4248011	p.Ser500Arg	missense_variant	1.0	ethambutol
embB	4248014	p.Thr501Ala	missense_variant	1.0	ethambutol	Uncertain significance
embB	4248035	p.Val508Ile	missense_variant	1.0	ethambutol
embB	4248040	c.1527C>G	synonymous_variant	1.0	ethambutol
embB	4248041	p.Ala510Thr	missense_variant	1.0	ethambutol	Uncertain significance
embB	4248044	p.Lys511Ala	missense_variant	1.0	ethambutol
embB	4248070	c.1557T>C	synonymous_variant	0.95	ethambutol
embB	4248085	c.1572T>C	synonymous_variant	0.91	ethambutol
embB	4248097	c.1584C>G	synonymous_variant	0.91	ethambutol
embB	4248130	c.1617G>C	synonymous_variant	0.93	ethambutol
embB	4248142	c.1629T>C	synonymous_variant	0.93	ethambutol
embB	4248143	c.1630T>C	synonymous_variant	0.93	ethambutol
embB	4248157	c.1644A>G	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
embB	4248172	c.1659G>C	synonymous_variant	0.94	ethambutol
embB	4248199	c.1686A>G	synonymous_variant	0.94	ethambutol
embB	4248200	p.Ile563Val	missense_variant	0.94	ethambutol
embB	4248205	c.1692C>G	synonymous_variant	0.94	ethambutol
embB	4248206	p.Ser565Gly	missense_variant	0.94	ethambutol	Uncertain significance
embB	4248220	c.1707A>C	synonymous_variant	1.0	ethambutol
embB	4248304	c.1791G>C	synonymous_variant	1.0	ethambutol
embB	4248316	c.1803C>G	synonymous_variant	1.0	ethambutol
embB	4248319	c.1806A>G	synonymous_variant	1.0	ethambutol
embB	4248343	c.1830G>C	synonymous_variant	1.0	ethambutol
embB	4248350	c.1837T>C	synonymous_variant	1.0	ethambutol
embB	4248355	c.1842A>G	synonymous_variant	1.0	ethambutol
embB	4248358	c.1845C>G	synonymous_variant	1.0	ethambutol
embB	4248361	c.1848A>C	synonymous_variant	1.0	ethambutol
embB	4248362	p.Ser617Ala	missense_variant	1.0	ethambutol
embB	4248373	c.1860C>G	synonymous_variant	1.0	ethambutol
embB	4248382	c.1869C>G	synonymous_variant	1.0	ethambutol
embB	4248386	c.1873C>A	synonymous_variant	1.0	ethambutol
embB	4248407	p.Leu632Val	missense_variant	1.0	ethambutol
embB	4248410	p.Phe633Leu	missense_variant	1.0	ethambutol
embB	4248419	p.Leu636Met	missense_variant	1.0	ethambutol
embB	4248425	c.1912T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4248430	c.1917T>C	synonymous_variant	1.0	ethambutol
embB	4248432	p.Trp640Phe	missense_variant	1.0	ethambutol
embB	4248457	c.1944T>C	synonymous_variant	1.0	ethambutol
embB	4248472	c.1959T>C	synonymous_variant	1.0	ethambutol
embB	4249342	c.2829C>G	synonymous_variant	1.0	ethambutol
embB	4249348	c.2835G>C	synonymous_variant	1.0	ethambutol
embB	4249351	c.2838C>G	synonymous_variant	1.0	ethambutol
embB	4249369	c.2856T>C	synonymous_variant	1.0	ethambutol
embB	4249375	c.2862G>C	synonymous_variant	1.0	ethambutol
embB	4249381	c.2868A>G	synonymous_variant	1.0	ethambutol
embB	4249384	c.2871G>T	synonymous_variant	1.0	ethambutol
embB	4249417	c.2904A>G	synonymous_variant	1.0	ethambutol
embB	4249423	p.Asp970Glu	missense_variant	1.0	ethambutol	Uncertain significance
embB	4249424	p.Leu971Met	missense_variant	1.0	ethambutol
embB	4249429	c.2916C>T	synonymous_variant	1.0	ethambutol
embB	4249432	c.2919A>G	synonymous_variant	1.0	ethambutol
embB	4249441	c.2928A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4249444	c.2931T>C	synonymous_variant	1.0	ethambutol
embB	4249469	p.Leu986Met	missense_variant	1.0	ethambutol
embB	4249486	c.2973T>G	synonymous_variant	1.0	ethambutol
embB	4249498	c.2985G>C	synonymous_variant	1.0	ethambutol
embB	4249521	p.Ala1003Val	missense_variant	1.0	ethambutol
embB	4249525	c.3012T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4249529	p.Ile1006Val	missense_variant	1.0	ethambutol
embB	4249532	p.Ala1007Thr	missense_variant	1.0	ethambutol	Uncertain significance
embB	4249537	c.3024A>G	synonymous_variant	1.0	ethambutol
embB	4249543	c.3030G>C	synonymous_variant	1.0	ethambutol
embB	4249546	c.3033G>A	synonymous_variant	1.0	ethambutol
embB	4249558	c.3045A>C	synonymous_variant	1.0	ethambutol
embB	4249568	p.Ser1019Thr	missense_variant	1.0	ethambutol
embB	4249573	c.3060T>C	synonymous_variant	1.0	ethambutol
embB	4249580	p.Leu1023Met	missense_variant	1.0	ethambutol
embB	4249594	c.3081G>C	synonymous_variant	1.0	ethambutol
aftB	4267241	c.1596G>C	synonymous_variant	1.0	ethambutol
aftB	4267244	c.1593T>C	synonymous_variant	1.0	ethambutol
aftB	4267256	c.1581C>G	synonymous_variant	1.0	ethambutol
aftB	4267262	c.1575T>C	synonymous_variant	1.0	ethambutol
aftB	4267266	p.Ala524Gly	missense_variant	0.91	ethambutol
aftB	4267268	c.1569T>C	synonymous_variant	0.91	ethambutol
aftB	4267274	c.1563G>C	synonymous_variant	0.91	ethambutol
aftB	4267289	p.Ala516Gln	missense_variant	0.83	ethambutol
aftB	4267292	c.1545C>G	synonymous_variant	0.83	ethambutol
aftB	4267297	c.1540T>C	synonymous_variant	0.83	ethambutol
aftB	4267301	c.1536C>T	synonymous_variant	0.83	ethambutol
aftB	4267304	p.Val511Ala	missense_variant	0.83	ethambutol
aftB	4267316	c.1521A>G	synonymous_variant	0.83	ethambutol
aftB	4267325	c.1512G>C	synonymous_variant	0.83	ethambutol
aftB	4267334	c.1503T>C	synonymous_variant	0.83	ethambutol	Not assoc w R - Interim
aftB	4267580	c.1257G>T	synonymous_variant	0.8	ethambutol

TB-Profiler result