TB-Profiler result

Run: ERR1023509

Summary

Run ID: ERR1023509

Sample name:

Date: 2024-10-04T14:24:49.045674

Number of reads: 291200

Percentage reads mapped: 5.35

Median coverage: 6.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.9
lineage4.9 Euro-American (H37Rv-like) None 0.95
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.97 amikacin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
kanamycin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.96 amikacin Assoc w R
capreomycin Assoc w R
kanamycin Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5302 c.63A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5359 c.120C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5363 c.124_126delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.9 levofloxacin
moxifloxacin
fgd1 491106 c.324T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491154 p.Glu124Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491163 c.381G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575561 p.Met72Val missense_variant 1.0 isoniazid
ethionamide
mshA 575586 p.Ala80Gly missense_variant 1.0 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575593 c.246G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575596 c.249C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575629 c.282A>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575633 p.Ala96Thr missense_variant 1.0 isoniazid
ethionamide
mshA 575652 p.Arg102Gln missense_variant 1.0 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575662 c.315C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575686 c.339G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575692 c.345G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575732 c.385_387delCTTinsTTG synonymous_variant 1.0 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575767 c.420G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575770 c.423G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575772 p.Val142Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>C synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620325 c.435G>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620337 c.447C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620404 c.514C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
hadA 732263 p.Val112Met missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732319 c.390G>A synonymous_variant 1.0 isoniazid
hadA 732322 p.Glu131Asp missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732361 c.432C>T synonymous_variant 1.0 isoniazid
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>T synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734616 c.363C>A synonymous_variant 1.0 rifampicin
nusG 734631 c.378G>A synonymous_variant 1.0 rifampicin
nusG 734634 c.381G>C synonymous_variant 1.0 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734652 c.399T>C synonymous_variant 1.0 rifampicin
nusG 734661 c.408A>C synonymous_variant 1.0 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.92 rifampicin
nusG 734670 c.417G>A synonymous_variant 1.0 rifampicin
nusG 734673 c.420A>G synonymous_variant 1.0 rifampicin
nusG 734680 p.Ala143Ser missense_variant 1.0 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734712 c.459G>C synonymous_variant 1.0 rifampicin
nusG 734718 c.465G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 1.0 rifampicin
nusG 734722 p.Thr157Ala missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>A synonymous_variant 1.0 rifampicin
nusG 734736 c.483C>G synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 1.0 rifampicin
nusG 734762 p.Ala170Val missense_variant 1.0 rifampicin
nusG 734769 c.516G>A synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734790 c.537G>C synonymous_variant 1.0 rifampicin
nusG 734793 c.540C>T synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760202 c.396G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.92 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760409 c.603C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>G synonymous_variant 0.85 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 0.85 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 0.9 rifampicin
rpoB 760625 c.819C>A synonymous_variant 0.93 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>C synonymous_variant 1.0 rifampicin
rpoB 760868 c.1062C>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.73 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 0.73 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760971 p.Arg389Ser missense_variant 0.33 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.69 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>T synonymous_variant 0.84 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761018 c.1212G>A synonymous_variant 0.83 rifampicin
rpoB 761021 c.1215G>C synonymous_variant 0.83 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761064 p.Ala420Ser missense_variant 0.81 rifampicin Uncertain significance
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.78 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.75 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.8 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.75 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 1.0 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761948 c.2142G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>A synonymous_variant 1.0 rifampicin
rpoB 761955 p.Ile717Phe missense_variant 0.79 rifampicin
rpoB 761973 p.His723Tyr missense_variant 0.88 rifampicin
rpoB 761980 p.Tyr725Phe missense_variant 0.88 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 0.85 rifampicin
rpoB 762003 p.Asn733Gln missense_variant 0.85 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762015 p.Glu737Gln missense_variant 0.87 rifampicin
rpoB 762020 p.Glu738Asp missense_variant 1.0 rifampicin
rpoB 762026 c.2220G>T synonymous_variant 1.0 rifampicin
rpoB 762030 p.Thr742Ser missense_variant 0.87 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762084 p.Ala760Pro missense_variant 0.88 rifampicin
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 0.93 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.9 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.9 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762152 c.2346C>A synonymous_variant 0.9 rifampicin
rpoB 762156 p.Val784Ile missense_variant 0.89 rifampicin
rpoB 762161 c.2355C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762189 p.Ile795Leu missense_variant 0.9 rifampicin
rpoB 762194 c.2388G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>G synonymous_variant 0.89 rifampicin
rpoB 762278 c.2472C>T synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 p.Leu831Met missense_variant 0.81 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762426 p.Ser874Thr missense_variant 0.5 rifampicin Uncertain significance
rpoC 762443 c.-927G>C upstream_gene_variant 0.5 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 762458 c.-912C>A upstream_gene_variant 0.5 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762475 p.Gly890Ala missense_variant 0.47 rifampicin
rpoB 762477 p.Lys891Arg missense_variant 0.5 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 1.0 rifampicin
rpoB 762849 p.Tyr1015Glu missense_variant 0.53 rifampicin
rpoB 762855 p.Val1017Met missense_variant 0.53 rifampicin
rpoB 762858 p.Thr1018Ser missense_variant 0.58 rifampicin
rpoB 762863 c.3057T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 762866 c.-504C>G upstream_gene_variant 0.65 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.74 rifampicin Uncertain significance
rpoB 762899 c.3093G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.76 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.55 rifampicin
rpoB 763014 p.Met1070Leu missense_variant 0.57 rifampicin
rpoB 763017 p.Gln1071Glu missense_variant 0.58 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.58 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763038 p.Thr1078Ala missense_variant 0.69 rifampicin
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.69 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.56 rifampicin
rpoB 763077 p.Val1091Thr missense_variant 0.56 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.71 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.71 rifampicin
rpoC 763160 c.-210G>C upstream_gene_variant 0.59 rifampicin
rpoB 763161 p.Leu1119Ile missense_variant 0.6 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763170 p.Leu1122Met missense_variant 0.53 rifampicin
rpoC 763178 c.-192G>C upstream_gene_variant 0.56 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 0.53 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 0.59 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.76 rifampicin
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.83 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.88 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.9 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763621 c.252delCinsTTCG conservative_inframe_insertion&synonymous_variant 0.94 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.91 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.92 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.87 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763772 p.Val135Met missense_variant 0.71 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764309 c.940_942delCTCinsTTG synonymous_variant 0.47 rifampicin
rpoC 764317 c.948C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764323 c.954G>A synonymous_variant 0.59 rifampicin
rpoC 764326 c.957G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764338 p.Glu323Asp missense_variant 0.65 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764357 c.988_990delCTCinsTTG synonymous_variant 0.75 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>A synonymous_variant 0.88 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGT synonymous_variant 1.0 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.85 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764491 c.1122G>T synonymous_variant 0.79 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764498 p.Ser377Ala missense_variant 0.71 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764507 p.Ala380Ser missense_variant 0.7 rifampicin
rpoC 764512 c.1143G>C synonymous_variant 0.71 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>G synonymous_variant 0.79 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.81 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.83 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.87 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.87 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.87 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764706 p.Leu446Gln missense_variant 0.93 rifampicin Uncertain significance
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764759 p.Asn464Asp missense_variant 0.94 rifampicin
rpoC 764763 p.His465Leu missense_variant 0.93 rifampicin
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.93 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764810 p.Pro481Ser missense_variant 0.9 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764843 p.Ala492Thr missense_variant 0.84 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>T synonymous_variant 0.76 rifampicin
rpoC 764887 c.1518G>T synonymous_variant 0.72 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.74 rifampicin
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765526 c.2157C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 1.0 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765610 c.2241C>T synonymous_variant 1.0 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 1.0 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 0.81 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 0.8 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766417 c.3048C>T synonymous_variant 0.73 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 1.0 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 1.0 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 1.0 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 1.0 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 1.0 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 1.0 linezolid
rplC 800817 c.9A>C synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801216 c.408C>A synonymous_variant 1.0 linezolid
rplC 801219 c.411C>T synonymous_variant 1.0 linezolid
rplC 801220 p.Ser138Ala missense_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 1.0 linezolid
rplC 801252 c.444G>C synonymous_variant 1.0 linezolid
rplC 801267 c.459A>T synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801297 c.489C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
fbiC 1303659 c.729T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303661 p.Val244Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303689 c.759T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304556 c.1626C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304598 c.1668C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304649 c.1719C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304679 c.1749G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305150 c.2220C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305159 c.2229G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305162 c.2232C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305165 c.2235G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305192 c.2262C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305204 c.2274C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
atpE 1461101 c.57T>C synonymous_variant 1.0 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 1.0 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 1.0 bedaquiline
atpE 1461161 c.117C>T synonymous_variant 1.0 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>A synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472107 n.262A>G non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.77 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.77 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.88 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.88 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472312 n.467_468insA non_coding_transcript_exon_variant 0.86 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.88 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472486 n.641A>G non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472495 n.650C>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.44 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.97 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473127 n.1282G>A non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Not assoc w R
amikacin Not assoc w R
rrs 1473201 n.1356A>G non_coding_transcript_exon_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.98 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473292 n.1447_1449delGGAinsTGGG non_coding_transcript_exon_variant 0.97 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473981 n.324delGinsTC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474116 n.459G>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474153 n.496C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474166 n.509G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474179 n.522C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474292 n.635_651delTTCCTCTCCGGAGGAGGinsGTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474356 n.699T>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474406 n.749T>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475273 n.1616T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475290 n.1633A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475697 n.2040C>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475702 n.2045G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsT non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476213 n.2556G>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476288 n.2631T>C non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.89 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476631 n.2974G>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673970 c.-232C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673982 c.-220G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833256 c.-286C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833262 c.-280T>A upstream_gene_variant 1.0 pyrazinamide
rpsA 1833271 c.-271G>A upstream_gene_variant 1.0 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833593 p.Ser18Thr missense_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833665 p.Thr42Val missense_variant 0.7 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.76 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.76 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.8 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.82 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.79 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.79 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833771 p.Asn77Thr missense_variant 0.79 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.73 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.68 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.67 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.55 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.55 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.55 pyrazinamide
rpsA 1833815 p.Thr92Gln missense_variant 0.55 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.57 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.64 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.7 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.83 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833893 p.Ala118Lys missense_variant 0.83 pyrazinamide
rpsA 1833896 p.Leu119Ile missense_variant 0.8 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.8 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.75 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.73 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.73 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.73 pyrazinamide
rpsA 1833925 c.384C>T synonymous_variant 0.75 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833994 c.453G>A synonymous_variant 0.88 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.88 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.94 pyrazinamide
rpsA 1834046 p.Ile169Val missense_variant 0.94 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834090 c.549G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834093 c.552G>T synonymous_variant 0.9 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834228 c.687C>T synonymous_variant 0.76 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834255 c.714C>G synonymous_variant 0.89 pyrazinamide
rpsA 1834258 c.717G>A synonymous_variant 0.89 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.92 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.92 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834307 p.Asp256Gln missense_variant 0.93 pyrazinamide
rpsA 1834312 c.771G>A synonymous_variant 0.94 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834395 p.Arg285Gln missense_variant 0.92 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.9 pyrazinamide Uncertain significance
rpsA 1834432 c.891G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834438 c.897C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.86 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.8 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.61 pyrazinamide
rpsA 1834538 p.Val333Leu missense_variant 0.53 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.43 pyrazinamide
bacA 2063667 c.1062G>A synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
streptomycin
amikacin
bacA 2063676 c.1053C>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063892 c.837T>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin Not assoc w R - Interim
amikacin
bacA 2063895 c.834C>A synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063901 c.828C>T synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063916 c.813C>A synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063919 c.810G>T synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064264 c.465C>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064269 c.460A>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
katG 2155661 p.Val151Ile missense_variant 0.63 isoniazid
katG 2155674 c.438G>C synonymous_variant 0.78 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155689 c.421_423delTTGinsCTC synonymous_variant 0.8 isoniazid Not assoc w R - Interim
katG 2155696 p.Ala139Val missense_variant 0.84 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155719 c.393G>C synonymous_variant 0.89 isoniazid
katG 2155722 c.390G>T synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>T synonymous_variant 0.91 isoniazid
katG 2155735 p.Met126Gln missense_variant 0.91 isoniazid
katG 2155741 p.Gly124Thr missense_variant 1.0 isoniazid
katG 2155743 c.369G>C synonymous_variant 1.0 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.91 isoniazid Not assoc w R - Interim
katG 2155755 c.357C>T synonymous_variant 0.91 isoniazid Not assoc w R - Interim
katG 2155764 p.His116Gln missense_variant 0.91 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.91 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>T synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518618 c.504G>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518648 c.534C>T synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>A synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518735 c.621C>A synonymous_variant 1.0 isoniazid
kasA 2518744 c.630C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>C synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518894 c.780G>A synonymous_variant 1.0 isoniazid
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783950 c.93C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 c.87T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067430 c.516C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067445 c.501C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.92 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.9 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.9 para-aminosalicylic_acid
thyA 3074247 c.225C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074252 p.Glu74Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074256 c.216G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074262 c.210T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074283 c.189G>A synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.92 para-aminosalicylic_acid
lpqB 3623510 c.1401C>T synonymous_variant 0.91 rifampicin
bedaquiline
lpqB 3624041 p.Glu290Asp missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
rpoA 3877836 c.672A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877872 c.636C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877886 p.Leu208Met missense_variant 1.0 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877899 p.Ser203Ala missense_variant 1.0 rifampicin
rpoA 3877902 p.Ile202Met missense_variant 0.79 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877926 p.Leu194Val missense_variant 1.0 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878085 c.423G>A synonymous_variant 1.0 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 1.0 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878126 c.382C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 1.0 rifampicin
rpoA 3878202 c.306G>C synonymous_variant 0.69 rifampicin
rpoA 3878211 c.297G>A synonymous_variant 0.64 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878241 p.Glu89His missense_variant 0.5 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.5 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878262 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878270 p.Leu80Ile missense_variant 0.47 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.53 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 1.0 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.67 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.75 rifampicin Uncertain significance
rpoA 3878977 c.-470C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.9 rifampicin
rpoA 3879043 c.-536C>G upstream_gene_variant 0.9 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879100 c.-593G>A upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986637 c.-207C>T upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3987028 p.Asn62Ser missense_variant 1.0 pretomanid
delamanid
ddn 3987035 c.192C>G synonymous_variant 1.0 pretomanid
delamanid
ddn 3987065 c.222T>C synonymous_variant 1.0 pretomanid
delamanid
ddn 3987071 c.228G>C synonymous_variant 1.0 pretomanid
delamanid
clpC1 4038271 p.Pro812Ala missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 c.2172C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038587 c.2118C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038745 p.Thr654Ala missense_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038800 c.1905C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 0.92 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.92 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038995 c.1710G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039009 c.1696C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1261_1263delCTAinsTTG synonymous_variant 1.0 pyrazinamide
clpC1 4039448 p.Pro419Ala missense_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>G synonymous_variant 0.48 pyrazinamide
clpC1 4039499 c.1206G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039524 p.Phe394His missense_variant 0.82 pyrazinamide
clpC1 4039541 c.1164C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039554 p.Thr384Asn missense_variant 0.86 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039562 p.Ala381Ser missense_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.89 pyrazinamide Uncertain significance
clpC1 4039574 c.1131G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039588 p.Ser373Thr missense_variant 0.89 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039640 p.Thr355Ala missense_variant 0.78 pyrazinamide
clpC1 4039647 p.Glu353Pro missense_variant 0.76 pyrazinamide
clpC1 4039649 p.Val352Ile missense_variant 0.76 pyrazinamide
clpC1 4039652 p.Thr351Ser missense_variant 0.81 pyrazinamide
clpC1 4039658 c.1047G>A synonymous_variant 0.72 pyrazinamide
clpC1 4039661 p.Gly348Gln missense_variant 1.0 pyrazinamide
clpC1 4039670 p.Val345Ile missense_variant 0.78 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.9 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039736 c.969C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039756 c.949C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039773 p.Lys311Met missense_variant 0.95 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039787 c.918G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>A synonymous_variant 0.98 pyrazinamide
clpC1 4039796 c.909C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.99 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.99 pyrazinamide
clpC1 4039838 p.Leu289Ile missense_variant 0.99 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.94 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039964 c.739_741delCTCinsTTG synonymous_variant 0.71 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.77 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 0.68 pyrazinamide
clpC1 4040001 p.His235Arg missense_variant 0.5 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.54 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.74 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040117 c.588A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040129 c.576C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.89 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040156 p.Met183His missense_variant 0.77 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040166 p.Ala180Gln missense_variant 0.83 pyrazinamide
clpC1 4040180 c.525C>T synonymous_variant 0.91 pyrazinamide
clpC1 4040636 c.69C>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
embC 4238954 c.-909C>T upstream_gene_variant 0.91 ethambutol
embC 4238963 c.-900C>T upstream_gene_variant 1.0 ethambutol Not assoc w R
embC 4238969 c.-894A>G upstream_gene_variant 0.91 ethambutol
embC 4238972 c.-891C>G upstream_gene_variant 0.91 ethambutol Uncertain significance
embC 4238975 c.-888A>C upstream_gene_variant 1.0 ethambutol
embC 4238986 c.-877C>A upstream_gene_variant 1.0 ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239014 c.-849C>G upstream_gene_variant 1.0 ethambutol
embC 4239027 c.-836_-834delATCinsCTG upstream_gene_variant 1.0 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239044 c.-819G>C upstream_gene_variant 1.0 ethambutol
embC 4239059 c.-804G>C upstream_gene_variant 1.0 ethambutol
embC 4239068 c.-795A>G upstream_gene_variant 1.0 ethambutol
embC 4239071 c.-792A>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239075 c.-788_-786delGCGinsACC upstream_gene_variant 1.0 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 1.0 ethambutol
embC 4239089 c.-774C>G upstream_gene_variant 1.0 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 1.0 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4240777 c.915G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240795 c.933C>G synonymous_variant 1.0 ethambutol
embC 4240801 c.939C>T synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>C synonymous_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244198 c.966C>A synonymous_variant 0.92 ethambutol
embA 4244207 c.975C>G synonymous_variant 0.92 ethambutol
embB 4245662 c.-852G>C upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 1.0 ethambutol
embA 4245693 p.Ile821Val missense_variant 1.0 ethambutol
embB 4245714 c.-800C>T upstream_gene_variant 1.0 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 1.0 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 1.0 ethambutol
embA 4246020 p.Ala930Thr missense_variant 1.0 ethambutol
embA 4246028 c.2796G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246082 c.-432T>C upstream_gene_variant 1.0 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 1.0 ethambutol
embA 4246254 p.Leu1008Met missense_variant 1.0 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 1.0 ethambutol
embA 4246265 c.3033C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246268 c.-246G>A upstream_gene_variant 1.0 ethambutol
embA 4246279 p.Ala1016Val missense_variant 1.0 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 1.0 ethambutol
embB 4246307 c.-207G>C upstream_gene_variant 1.0 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 1.0 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 1.0 ethambutol
embB 4247975 p.Val488Ile missense_variant 0.91 ethambutol Uncertain significance
embB 4248001 c.1488C>T synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4248042 p.Ala510Gly missense_variant 1.0 ethambutol
embB 4248052 c.1539G>T synonymous_variant 1.0 ethambutol
embB 4248055 c.1542G>C synonymous_variant 1.0 ethambutol
embB 4248058 c.1545C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248061 c.1548G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248064 c.1551G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248094 c.1581C>T synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248154 c.1641G>T synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>T synonymous_variant 1.0 ethambutol
embB 4248163 c.1650G>A synonymous_variant 1.0 ethambutol
embB 4248169 c.1656C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>A synonymous_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 1.0 ethambutol
embB 4248217 c.1704C>G synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248266 c.1753C>T synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 1.0 ethambutol
embB 4248349 c.1836G>A synonymous_variant 1.0 ethambutol
embB 4248358 c.1845C>G synonymous_variant 1.0 ethambutol
embB 4248361 c.1848A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248379 c.1866G>A synonymous_variant 1.0 ethambutol
embB 4248407 p.Leu632Val missense_variant 1.0 ethambutol
embB 4248412 p.Phe633Leu missense_variant 1.0 ethambutol
embB 4248416 p.Leu635Met missense_variant 1.0 ethambutol
embB 4248424 c.1911G>A synonymous_variant 1.0 ethambutol
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4249501 c.2988C>T synonymous_variant 1.0 ethambutol
embB 4249521 p.Ala1003Val missense_variant 1.0 ethambutol
embB 4249525 c.3012T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 1.0 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249540 c.3027C>T synonymous_variant 1.0 ethambutol
embB 4249546 c.3033G>A synonymous_variant 1.0 ethambutol
ethA 4326520 p.Glu318Asp missense_variant 1.0 ethionamide
ethA 4326523 c.951T>C synonymous_variant 1.0 ethionamide
ethA 4326535 c.939G>C synonymous_variant 1.0 ethionamide
ethR 4326556 c.-993A>G upstream_gene_variant 1.0 ethionamide