TB-Profiler result

Run: SRR1184346
Summary

Run ID: SRR1184346

Sample name:

Date: 2024-10-05T08:55:25.451747

Number of reads: 777536

Percentage reads mapped: 47.4

Median coverage: 16.0

Strain: lineage3.1

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.11
lineage3.1 East-African-Indian RD750 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.Met306Ile Assoc w R
pyrazinamide pncA p.Trp68Cys Assoc w R
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance Mutation from literature
katG 2155168 p.Ser315Thr missense_variant 0.77 isoniazid Assoc w R High-level resistance
pncA 2289038 p.Trp68Cys missense_variant 1.0 pyrazinamide Assoc w R
embB 4247431 p.Met306Ile missense_variant 0.7 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 558 c.558G>C synonymous_variant 0.25 isoniazid
dnaA 561 c.561C>T synonymous_variant 0.24 isoniazid
dnaA 567 c.567C>G synonymous_variant 0.25 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.27 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 0.32 isoniazid
dnaA 588 c.588A>C synonymous_variant 0.31 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.31 isoniazid
dnaA 600 c.600T>G synonymous_variant 0.28 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.3 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.28 isoniazid Not assoc w R - Interim
dnaA 693 c.693A>G synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.31 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.33 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.23 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.24 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.23 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.23 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.25 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.22 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.2 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.38 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.38 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.4 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.42 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.39 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.42 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.47 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.49 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.5 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.53 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.44 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.42 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.38 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.38 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.41 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.39 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.38 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.32 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.32 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.33 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.43 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.46 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.52 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.57 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.6 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.58 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.58 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.48 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.52 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.52 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.56 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.62 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.61 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.61 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.61 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.61 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.61 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.65 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.7 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.68 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.67 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.67 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.53 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 0.47 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.47 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.47 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.5 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.48 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.5 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.5 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.6 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.62 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.63 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.63 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.67 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.67 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.67 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.71 isoniazid
gyrB 5824 c.585A>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 5849 c.610C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.48 levofloxacin
moxifloxacin
gyrB 6248 c.1009_1011delCTAinsTTG synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6622 c.-680C>T upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.51 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.43 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.42 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7015 c.-287G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>A upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7246 c.2007T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 7347 p.Glu16Gln missense_variant 0.36 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7670 c.369A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8156 c.855T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.42 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.45 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.46 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 8387 c.1086C>T synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 p.Tyr364His missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318_1320delTTGinsCTA synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.56 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.76 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
Rv0010c 13484 c.75T>C synonymous_variant 0.9 isoniazid Not assoc w R - Interim
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.47 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.48 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.55 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.52 isoniazid
fgd1 490782 c.-1G>C upstream_gene_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 490797 c.15G>A synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>C synonymous_variant 0.59 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 490827 c.45C>T synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 490848 c.66A>G synonymous_variant 0.69 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 490868 p.Ala29Gly missense_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>A synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 490890 c.108C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491553 c.771G>A synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 575084 c.-264T>C upstream_gene_variant 0.47 isoniazid
ethionamide
mshA 575117 c.-231T>C upstream_gene_variant 0.5 isoniazid
ethionamide
mshA 575118 c.-230_-228delACGinsGCC upstream_gene_variant 0.5 isoniazid
ethionamide
mshA 575124 c.-224_-222delGGGinsCGC upstream_gene_variant 0.44 isoniazid
ethionamide
mshA 575137 c.-211C>G upstream_gene_variant 0.57 isoniazid
ethionamide
mshA 575144 c.-204T>C upstream_gene_variant 0.53 isoniazid
ethionamide
mshA 575154 c.-194_-192delGTGinsCTC upstream_gene_variant 0.44 isoniazid
ethionamide
mshA 575161 c.-187_-186delTTinsCG upstream_gene_variant 0.47 isoniazid
ethionamide
ccsA 619570 c.-321G>C upstream_gene_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 619574 c.-317G>A upstream_gene_variant 0.61 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.61 kanamycin
capreomycin
amikacin
ccsA 619584 c.-307A>T upstream_gene_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 619594 c.-297G>T upstream_gene_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 619609 c.-282G>C upstream_gene_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>A upstream_gene_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 619645 c.-246G>C upstream_gene_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>T upstream_gene_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 619676 c.-215C>G upstream_gene_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.46 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>T synonymous_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.48 kanamycin
capreomycin
amikacin
Rv0565c 656418 c.1053A>G synonymous_variant 0.53 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.58 ethionamide
Rv0565c 656448 p.Ile341Val missense_variant 0.5 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.52 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.52 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.55 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.5 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.5 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.5 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.46 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.39 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.33 ethionamide Not assoc w R - Interim
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657237 c.234A>G synonymous_variant 0.38 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.38 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.35 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.33 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.33 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.36 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.33 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.29 ethionamide
Rv0565c 657601 c.-131A>C upstream_gene_variant 0.4 ethionamide
Rv0565c 657602 c.-132C>T upstream_gene_variant 0.43 ethionamide
Rv0565c 657605 c.-137_-135delATCinsCAA upstream_gene_variant 0.4 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.54 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.58 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.5 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.45 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.47 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.43 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 0.38 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.55 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.67 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.67 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.61 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.58 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.41 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.35 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.27 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.27 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.37 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.35 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.35 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.35 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.42 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.48 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.44 isoniazid
hadA 732337 c.408G>A synonymous_variant 0.48 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.55 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.58 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.58 isoniazid
nusG 734132 c.-122G>C upstream_gene_variant 0.3 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.29 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 0.24 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.24 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.39 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.37 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.36 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.38 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.41 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.41 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.46 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.45 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.48 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.56 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.56 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.56 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.39 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.37 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.36 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.37 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.24 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.35 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>C synonymous_variant 0.45 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.45 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.45 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.43 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.43 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.48 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.48 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.35 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.36 rifampicin
rpoB 759746 c.-61C>T upstream_gene_variant 0.87 rifampicin Not assoc w R
rpoB 760181 c.375T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.47 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.5 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.5 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.52 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.52 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.5 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.48 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.5 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.6 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.6 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.74 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.46 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.42 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760591 p.Val262Ala missense_variant 0.59 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.56 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.44 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.5 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.42 rifampicin
rpoB 760869 p.Val355Ile missense_variant 0.42 rifampicin Uncertain significance
rpoB 760925 c.1119T>C synonymous_variant 0.54 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.54 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.56 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.6 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.59 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.57 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.43 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.43 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.54 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.44 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.28 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.44 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.42 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.44 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.63 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.64 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.71 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.71 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.52 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.57 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.54 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.71 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.73 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.73 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.69 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.69 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.69 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.73 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.58 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.57 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.55 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.55 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.73 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.78 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.81 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.79 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.8 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.81 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.78 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.79 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.77 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.78 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.76 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.71 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.71 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762413 c.2607G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.75 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.62 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.62 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.67 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.67 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.68 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.56 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.56 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.56 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.48 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.35 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.38 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.4 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.4 rifampicin Uncertain significance
rpoB 762810 p.Ala1002Ser missense_variant 0.47 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.47 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.74 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.78 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.77 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.5 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.47 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.28 rifampicin
rpoB 763206 p.Ser1134Trp missense_variant 0.19 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.26 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.24 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.25 rifampicin
rpoC 763402 c.33C>G synonymous_variant 0.44 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.45 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.55 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.6 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.71 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.82 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.85 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.85 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.84 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.86 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.83 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.81 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.8 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.79 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.83 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.82 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.82 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.82 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.78 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.75 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.86 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.75 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763915 c.546C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763942 c.573C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.47 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.4 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.4 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.38 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.36 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764059 c.690G>T synonymous_variant 0.38 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.55 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.58 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.59 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.69 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.52 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.54 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.53 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.64 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.65 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.65 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.73 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.63 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.5 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.5 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.52 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.62 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.5 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.36 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.38 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.39 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.38 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765364 c.1995G>A synonymous_variant 0.52 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.55 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.57 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.56 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.58 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.59 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.51 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.53 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.56 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.56 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.59 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.54 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.57 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.54 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.48 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.45 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.42 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.42 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.44 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.62 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.62 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.63 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.68 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.66 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.66 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.65 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.64 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.72 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.79 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.71 rifampicin
rpoC 766132 c.2763C>T synonymous_variant 0.71 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.71 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766288 c.2919C>G synonymous_variant 0.35 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.47 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.5 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.57 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.55 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.57 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.58 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.62 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.6 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.58 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.56 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.59 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.57 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.69 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.68 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.7 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.63 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.63 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.63 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.45 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.47 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.5 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.55 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.64 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.61 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.59 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.68 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.71 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.67 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.71 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.71 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.71 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.71 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.65 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.75 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.69 rifampicin
rpoC 766795 c.3426C>T synonymous_variant 0.71 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.63 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.53 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.62 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.41 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.41 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.39 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.45 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.5 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.57 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.66 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.64 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.46 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776654 c.1827A>C synonymous_variant 0.42 bedaquiline
clofazimine
mmpL5 776664 p.Thr606Gly missense_variant 0.37 bedaquiline
clofazimine
mmpL5 776678 c.1803G>C synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 776693 p.Val596Ala missense_variant 0.33 bedaquiline
clofazimine
mmpL5 776705 c.1776C>T synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 776729 c.1752C>T synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 777133 p.Val450Ile missense_variant 0.26 bedaquiline
clofazimine
mmpL5 777158 c.1323C>G synonymous_variant 0.29 bedaquiline
clofazimine
mmpL5 777164 c.1317C>G synonymous_variant 0.3 bedaquiline
clofazimine
mmpL5 777170 c.1311T>C synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 777176 p.Glu435Asp missense_variant 0.34 bedaquiline
clofazimine
mmpL5 777191 c.1290C>G synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 0.32 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.26 bedaquiline
clofazimine
mmpL5 777212 p.Ala423Thr missense_variant 0.3 bedaquiline
clofazimine
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.5 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.53 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.53 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.56 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.56 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.58 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.56 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.47 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.5 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.61 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.56 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.5 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.47 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.5 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.5 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.45 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.43 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.53 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.5 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.49 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.49 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.53 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.54 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.55 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.6 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.58 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.63 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.62 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.64 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.67 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.66 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.64 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.59 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.62 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.6 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.64 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.67 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.67 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.68 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.7 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.72 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.68 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.72 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.48 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.48 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.46 linezolid
rplC 800814 c.6A>G synonymous_variant 0.41 linezolid
rplC 800817 c.9A>T synonymous_variant 0.4 linezolid
rplC 800844 c.36T>C synonymous_variant 0.4 linezolid
rplC 800865 c.57A>G synonymous_variant 0.28 linezolid
rplC 801300 c.492C>G synonymous_variant 0.47 linezolid
rplC 801309 c.501C>G synonymous_variant 0.52 linezolid
rplC 801312 c.504G>C synonymous_variant 0.55 linezolid
rplC 801321 c.513C>T synonymous_variant 0.57 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.57 linezolid
rplC 801339 c.531T>C synonymous_variant 0.57 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.57 linezolid
rplC 801348 c.540T>G synonymous_variant 0.56 linezolid
rplC 801357 c.549T>C synonymous_variant 0.55 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.61 linezolid
rplC 801402 c.594T>C synonymous_variant 0.5 linezolid
rplC 801405 c.597T>C synonymous_variant 0.47 linezolid
rplC 801423 c.615G>C synonymous_variant 0.45 linezolid
rplC 801426 c.618C>G synonymous_variant 0.45 linezolid
rplC 801427 p.Met207Val missense_variant 0.46 linezolid
rplC 801438 c.630T>C synonymous_variant 0.48 linezolid
rplC 801442 p.Ile212Val missense_variant 0.45 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
fbiC 1303480 p.Gln184Glu missense_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303489 c.559C>T synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303497 c.567G>A synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303501 c.571C>T synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303521 c.591C>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303530 c.600G>A synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303539 c.609G>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.45 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303761 c.831T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303797 c.867A>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304161 p.Arg411Ser missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304187 c.1257T>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304208 c.1278C>T synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304535 c.1605G>A synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304545 p.Val539Thr missense_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>T synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.57 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.68 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1305372 c.2442G>A synonymous_variant 0.39 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305384 c.2454G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1305396 c.2466C>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1305405 c.2475A>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305417 c.2487C>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
sigE 1364862 c.450C>A synonymous_variant 0.47 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.47 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.5 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.5 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.55 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.6 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.57 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.48 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.43 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.4 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.39 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.41 pyrazinamide
atpE 1461170 c.126A>G synonymous_variant 0.33 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.42 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.44 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.52 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.41 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.41 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.43 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.37 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.39 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.35 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.37 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.51 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.65 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.53 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.82 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.42 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.67 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476733 n.3076C>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
inhA 1673523 c.-679G>T upstream_gene_variant 0.42 isoniazid
ethionamide
inhA 1673535 c.-667A>G upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673548 c.-654G>A upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673568 c.-634C>G upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673633 c.-569G>A upstream_gene_variant 0.35 isoniazid
ethionamide
inhA 1673637 c.-565C>G upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673641 c.-561G>A upstream_gene_variant 0.44 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673657 c.-545C>A upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.6 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.63 isoniazid
ethionamide
inhA 1673679 c.-523T>G upstream_gene_variant 0.78 isoniazid
ethionamide
inhA 1673685 c.-517C>T upstream_gene_variant 0.79 isoniazid
ethionamide
inhA 1673710 c.-492C>A upstream_gene_variant 0.88 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 0.88 isoniazid
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 0.8 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.55 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673758 c.-444A>G upstream_gene_variant 0.61 isoniazid
ethionamide
inhA 1673890 c.-312G>T upstream_gene_variant 0.4 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.39 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.45 isoniazid
ethionamide
inhA 1673916 c.-286A>C upstream_gene_variant 0.52 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 0.54 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 0.64 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 0.65 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.72 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.63 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 0.48 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 0.48 isoniazid
ethionamide
inhA 1674114 c.-88T>A upstream_gene_variant 0.55 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.57 isoniazid
ethionamide
inhA 1674126 c.-76G>C upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 0.71 isoniazid
ethionamide
inhA 1674136 c.-66T>G upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1674141 c.-61T>C upstream_gene_variant 0.71 isoniazid
ethionamide
inhA 1674156 c.-46C>G upstream_gene_variant 0.61 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.37 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674504 c.303C>G synonymous_variant 0.54 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.61 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.59 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.54 isoniazid
ethionamide
inhA 1674552 c.351C>G synonymous_variant 0.56 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.58 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.53 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674672 c.471C>G synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.53 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.32 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674828 c.627G>A synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.57 isoniazid
ethionamide
inhA 1674864 c.663C>T synonymous_variant 0.65 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.72 isoniazid
ethionamide
inhA 1674900 c.699G>A synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.68 isoniazid
ethionamide
inhA 1674909 c.708G>A synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674960 c.759C>G synonymous_variant 0.24 isoniazid
ethionamide
rpsA 1833554 p.Thr5Ala missense_variant 0.48 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.52 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.56 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.59 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.63 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.45 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.42 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.42 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.38 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.35 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.36 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.39 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.33 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.31 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.34 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.37 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.45 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.58 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.62 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.63 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.52 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.49 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.43 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.43 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.4 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.37 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.53 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.55 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.51 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.51 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.52 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.58 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.74 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834510 c.969C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.72 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.74 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.69 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.72 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.76 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.79 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.77 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.77 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.72 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.71 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.38 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.31 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.32 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.36 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917951 c.12T>C synonymous_variant 0.58 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.67 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.67 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.69 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.69 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 0.67 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.67 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.54 capreomycin
tlyA 1918248 c.309T>C synonymous_variant 0.39 capreomycin
tlyA 1918251 c.312T>G synonymous_variant 0.39 capreomycin
tlyA 1918258 p.His107Glu missense_variant 0.37 capreomycin
tlyA 1918271 p.Ala111Val missense_variant 0.32 capreomycin
tlyA 1918275 c.336T>C synonymous_variant 0.32 capreomycin
tlyA 1918278 c.339C>G synonymous_variant 0.33 capreomycin
tlyA 1918310 p.Asn124Ser missense_variant 0.39 capreomycin
tlyA 1918315 p.Pro126Ala missense_variant 0.39 capreomycin
tlyA 1918323 c.384G>C synonymous_variant 0.35 capreomycin
tlyA 1918326 c.387G>C synonymous_variant 0.35 capreomycin
tlyA 1918330 p.Leu131Val missense_variant 0.36 capreomycin
bacA 2064972 c.-244T>C upstream_gene_variant 0.47 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.5 kanamycin
capreomycin
streptomycin
amikacin
ndh 2102212 c.831G>C synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2102218 c.825C>A synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102227 c.816C>T synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102230 c.813G>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102233 c.810G>A synonymous_variant 0.39 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102302 c.741G>C synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2102305 c.738T>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102638 c.405A>C synonymous_variant 0.45 isoniazid
delamanid
ethionamide
ndh 2102644 c.399A>G synonymous_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>G synonymous_variant 0.53 isoniazid
delamanid
ethionamide
ndh 2102680 c.363T>C synonymous_variant 0.53 isoniazid
delamanid
ethionamide
ndh 2102686 c.357G>C synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2102695 c.348C>T synonymous_variant 0.47 isoniazid
delamanid
ethionamide
ndh 2102700 c.343C>T synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2102710 c.333C>T synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2102718 p.Gln109Glu missense_variant 0.47 isoniazid
delamanid
ethionamide
katG 2155641 p.Lys157Asn missense_variant 0.27 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.32 isoniazid
katG 2155677 c.435C>G synonymous_variant 0.4 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.38 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.36 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.36 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.43 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.42 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.41 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.33 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.3 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.33 isoniazid
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
pncA 2289365 c.-125delC upstream_gene_variant 1.0 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.6 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.6 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.6 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.6 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.57 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.57 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.54 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.67 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.55 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.55 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.42 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.41 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.57 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.63 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.6 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.52 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.5 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.39 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.57 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.53 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.6 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.56 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.45 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.45 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.52 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.5 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.52 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.48 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.35 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.3 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.33 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.35 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.36 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.36 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.38 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.45 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.48 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.56 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.56 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.58 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.52 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.52 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.57 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.75 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.64 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.66 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.63 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.57 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.52 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.47 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.5 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.71 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 0.71 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.68 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.5 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.46 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.48 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.44 isoniazid
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0 isoniazid Not assoc w R
ahpC 2726564 c.372C>G synonymous_variant 0.44 isoniazid Not assoc w R - Interim
ahpC 2726591 c.399C>G synonymous_variant 0.53 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.56 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.53 isoniazid
ahpC 2726601 p.Ile137Leu missense_variant 0.56 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.54 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.59 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.66 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.5 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.5 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.5 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.54 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.57 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.59 isoniazid
ahpC 2726717 c.525A>G synonymous_variant 0.52 isoniazid
folC 2747059 c.540T>C synonymous_variant 0.4 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.4 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.42 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 0.44 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.64 para-aminosalicylic_acid
Rv2477c 2782393 c.1650C>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782396 c.1647G>A synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782399 c.1644T>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782408 c.1635T>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782411 c.1632C>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782414 p.Asp543Glu missense_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782418 p.Val542Ala missense_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2782420 c.1623T>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782423 c.1620C>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782432 p.Val537Ile missense_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782498 c.1545C>T synonymous_variant 0.36 kanamycin Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R
amikacin Not assoc w R
Rv2477c 2782513 c.1530G>T synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782930 c.1113G>A synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.5 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.57 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.43 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783107 c.936G>A synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.55 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.55 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.38 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.39 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.58 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.61 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.63 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.5 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2681 2996940 p.Gly68Asn missense_variant 0.58 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.64 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 0.7 capreomycin
Rv2681 2996966 c.228G>C synonymous_variant 0.64 capreomycin
Rv2681 2996972 c.234C>G synonymous_variant 0.64 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.7 capreomycin
Rv2681 2996976 p.Ala80Ser missense_variant 0.7 capreomycin
Rv2752c 3064973 p.Ala407Ser missense_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064974 c.1218T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064995 c.1197C>G synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064998 c.1194A>G synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065007 c.1185G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065013 c.1179G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065018 p.Asn392His missense_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065022 c.1170G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065028 p.Val388Ile missense_variant 0.54 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065040 c.1152C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065916 c.276T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065925 p.Ala89Gly missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065928 c.264G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065946 p.Gly82Ala missense_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065988 c.204A>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.44 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3066009 c.183G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066118 p.Asn25Ser missense_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.48 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066351 c.-160G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066357 c.-166G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066369 c.-180_-178delAGCinsGCG upstream_gene_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067313 c.633G>T synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067462 c.484C>T synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.5 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.39 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.5 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.56 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.59 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.6 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.6 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.68 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.67 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067637 c.309G>A synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.59 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.58 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.43 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.41 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.4 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.32 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.55 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.46 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 0.33 para-aminosalicylic_ac