TB-Profiler result

Run: ERR11252558
Summary

Run ID: ERR11252558

Sample name:

Date: 2024-10-05T10:50:34.950192

Number of reads: 227727

Percentage reads mapped: 38.61

Median coverage: 4.0

Strain: lineage4.6.3;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.6.3 Euro-American None 0.06
lineage4 Euro-American None 0.97
lineage4.9 Euro-American (H37Rv-like) None 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>C synonymous_variant 0.79 isoniazid
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 810 c.810C>G synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.9 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1080 c.1080C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.92 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>A synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.94 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 1.0 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 0.91 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.87 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.9 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.68 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
gyrB 6238 c.999G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6251 p.Leu338Phe missense_variant 0.41 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6283 c.1044C>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6334 c.-968G>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6838 c.-464C>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>A upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6901 c.-401G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>A upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>A upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7210 c.-92C>T upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7418 c.117C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7436 c.135C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7700 c.399G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCTC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7778 c.477G>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8120 c.819G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8129 c.828T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8138 c.837C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8337 c.1036_1038delCTAinsTTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8690 c.1389C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8759 c.1458C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8789 c.1488C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8894 c.1593C>A synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8951 c.1650G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
fgd1 491355 c.573C>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
mshA 574616 c.-732G>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574631 c.-717C>G upstream_gene_variant 0.69 isoniazid
ethionamide
mshA 574640 c.-708G>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574650 c.-698A>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574659 c.-689A>C upstream_gene_variant 0.69 isoniazid
ethionamide
mshA 574679 c.-669C>T upstream_gene_variant 0.69 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574683 c.-665T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 574694 c.-654C>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>A synonymous_variant 1.0 isoniazid
ethionamide
ccsA 619618 c.-273C>G upstream_gene_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 619627 c.-264C>G upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619630 c.-261C>G upstream_gene_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620343 c.453G>C synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>T synonymous_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620370 c.480C>A synonymous_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>A synonymous_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620430 c.540C>T synonymous_variant 0.73 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620442 c.552G>C synonymous_variant 0.69 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620449 p.Leu187Met missense_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620454 c.564C>G synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
Rv0565c 657695 c.-225C>T upstream_gene_variant 0.58 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.71 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731689 c.-241_-240insC upstream_gene_variant 1.0 isoniazid
hadA 731692 c.-238A>C upstream_gene_variant 1.0 isoniazid
hadA 731693 c.-237C>T upstream_gene_variant 0.91 isoniazid
hadA 731695 c.-235C>T upstream_gene_variant 0.91 isoniazid
hadA 731696 c.-234G>A upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232_-231insTCAGGAATTG upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 1.0 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.92 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.77 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.64 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.67 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.64 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.7 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.7 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734407 p.Val52Ile missense_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.7 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.77 rifampicin
nusG 734502 c.249G>A synonymous_variant 0.79 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734562 c.309G>A synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734750 p.Ser166Thr missense_variant 0.6 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.38 rifampicin
nusG 734757 c.504T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734762 p.Ala170Val missense_variant 0.38 rifampicin
nusG 734778 c.525G>C synonymous_variant 0.52 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734787 c.534T>C synonymous_variant 1.0 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.54 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 0.54 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.6 rifampicin
nusG 734841 c.588G>A synonymous_variant 0.7 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.76 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.95 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.37 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.41 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.42 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.48 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.42 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.54 rifampicin
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.62 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.85 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760754 c.948G>C synonymous_variant 1.0 rifampicin
rpoB 760755 p.His317Asn missense_variant 1.0 rifampicin
rpoB 760760 c.954C>G synonymous_variant 1.0 rifampicin
rpoB 760765 p.Glu320Ala missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760778 c.972G>C synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760916 c.1110C>G synonymous_variant 0.67 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.61 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.64 rifampicin
rpoB 761003 c.1197C>G synonymous_variant 0.38 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.62 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761124 c.1318C>T synonymous_variant 0.68 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.77 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.75 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.75 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.36 rifampicin
rpoB 761348 c.1542C>G synonymous_variant 0.37 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 0.52 rifampicin
rpoB 761384 c.1578C>G synonymous_variant 0.57 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.4 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761457 p.Pro551Lys missense_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 0.8 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.48 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.7 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.73 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.77 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763453 c.84C>T synonymous_variant 0.58 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763519 c.150G>A synonymous_variant 0.69 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 1.0 rifampicin
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763609 c.240C>G synonymous_variant 0.73 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>T synonymous_variant 0.77 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.85 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.85 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.83 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.86 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.75 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.74 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.52 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.46 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 c.507A>G synonymous_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763885 c.516C>G synonymous_variant 0.93 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763912 c.543G>C synonymous_variant 0.91 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 0.42 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.58 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.58 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>T synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.69 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764092 c.723C>T synonymous_variant 0.7 rifampicin
rpoC 764095 c.726C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.66 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.67 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764191 c.822C>T synonymous_variant 0.68 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 0.68 rifampicin
rpoC 764200 c.831G>C synonymous_variant 0.68 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.84 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>G synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.72 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>A synonymous_variant 0.82 rifampicin
rpoC 764489 c.1120C>T synonymous_variant 0.85 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764510 c.1141C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.87 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.86 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764651 p.Ser428Thr missense_variant 0.28 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>A synonymous_variant 0.73 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764915 c.1546C>T synonymous_variant 0.9 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.91 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764971 c.1602C>G synonymous_variant 0.95 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 0.97 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.93 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.93 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.94 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.94 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.93 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.93 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.92 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.9 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.92 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.66 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.66 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.7 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.7 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 1.0 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.71 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.72 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766474 c.3105C>T synonymous_variant 0.86 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766568 p.Val1067Ile missense_variant 0.91 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.9 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 0.61 rifampicin
rpoC 766627 c.3258G>C synonymous_variant 0.5 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.5 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.42 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.42 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.42 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 0.42 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.63 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766686 p.Glu1106Val missense_variant 0.38 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.96 rifampicin
rpoC 766756 c.3387G>A synonymous_variant 0.67 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 0.74 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.86 rifampicin
rpoC 766924 p.Glu1185Asp missense_variant 0.86 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.9 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767068 c.3699G>C synonymous_variant 0.8 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.73 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767186 p.Gln1273Glu missense_variant 0.35 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpsL 781658 c.99A>G synonymous_variant 0.81 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.94 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.94 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.93 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.86 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.83 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.33 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.65 streptomycin
rpsL 781829 c.270G>T synonymous_variant 0.33 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.67 streptomycin Not assoc w R - Interim
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.4 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.65 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 0.92 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
fbiC 1303441 c.511T>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1303464 c.534A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303476 c.546G>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303479 c.549G>A synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303480 p.Gln184Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303491 c.561G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303492 c.562T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303503 c.573G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303520 p.Ser197Thr missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303554 c.624G>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303557 c.627G>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304637 c.1707G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304901 c.1971C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304925 c.1995G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304934 c.2004C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304955 c.2025G>A synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304970 c.2040G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305276 c.2346G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305279 p.His783Gln missense_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1305282 c.2352T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305330 c.2400C>G synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305348 c.2418C>T synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1305361 c.2431C>T synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1305381 c.2451G>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1305396 c.2466C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305399 c.2469A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
atpE 1461107 c.63C>G synonymous_variant 1.0 bedaquiline
atpE 1461113 c.69C>A synonymous_variant 0.6 bedaquiline
atpE 1461125 c.81T>C synonymous_variant 0.64 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.62 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.64 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 1.0 bedaquiline
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.8 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.69 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474007 n.350A>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474036 n.379G>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474413 n.756_775delACCCACACGCGCATACGCGCinsCATCCCCTTTGGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475245 n.1588T>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475409 n.1752T>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid Uncertain significance
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.8 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673758 c.-444A>G upstream_gene_variant 0.67 isoniazid
ethionamide
inhA 1673778 c.-424C>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673787 c.-415G>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673796 c.-406G>T upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673799 c.-403T>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673805 c.-397G>C upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673808 c.-394A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673811 c.-391G>A upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673829 c.-373C>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673830 c.-372_-370delAAAinsCGT upstream_gene_variant 0.65 isoniazid
ethionamide
inhA 1673838 c.-364T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673841 c.-361A>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673844 c.-358G>C upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673847 c.-355A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673853 c.-349A>C upstream_gene_variant 0.61 isoniazid
ethionamide
inhA 1673856 c.-346T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673862 c.-340C>G upstream_gene_variant 0.61 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673916 c.-286A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673943 c.-259C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673946 c.-256C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673950 c.-252C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 0.6 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674037 c.-165C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674063 c.-139G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.68 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 0.77 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674628 p.Ser143Gly missense_variant 0.88 isoniazid
ethionamide
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674663 c.462G>A synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674669 c.468G>C synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674714 c.513C>G synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674743 p.Lys181Arg missense_variant 0.92 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674765 c.564C>G synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674783 c.582C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674792 c.591G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674825 c.624C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674834 c.633C>G synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674840 c.639C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674849 p.Gln216His missense_variant 0.9 isoniazid
ethionamide
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 0.78 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.76 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.77 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833739 c.198C>G synonymous_variant 0.66 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1833769 c.228C>G synonymous_variant 0.49 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 0.52 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.32 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.6 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 0.47 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.48 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.79 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.77 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.75 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.82 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.75 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.72 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
rpsA 1834210 c.669C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>A synonymous_variant 0.76 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.79 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.51 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 0.51 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.44 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.61 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.49 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 0.51 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 0.86 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
bacA 2064915 c.-187G>C upstream_gene_variant 0.82 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064927 c.-199G>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064942 c.-214G>T upstream_gene_variant 0.87 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2065004 c.-276T>C upstream_gene_variant 0.73 kanamycin
capreomycin
streptomycin
amikacin
bacA 2065008 c.-280C>T upstream_gene_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
ndh 2102317 c.726A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102389 c.654G>C synonymous_variant 0.85 isoniazid
delamanid
ethionamide
ndh 2102392 c.651C>G synonymous_variant 0.85 isoniazid
delamanid
ethionamide
ndh 2102398 c.645C>T synonymous_variant 0.86 isoniazid
delamanid
ethionamide
ndh 2102401 c.642T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102422 c.621C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102443 p.Ala200Ser missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102482 c.561A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102494 c.549T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102497 c.546T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102509 c.534T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102517 p.Val176Ile missense_variant 0.91 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2102518 c.525T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102527 c.516A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102533 c.510A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102545 c.498G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102644 c.399A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102668 c.375T>C synonymous_variant 0.5 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102683 c.360T>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.88 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.83 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>G synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.92 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.82 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.81 isoniazid
kasA 2518624 c.510C>G synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 0.83 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.81 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518671 p.Val186Ala missense_variant 0.76 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.78 isoniazid
kasA 2518687 c.573C>T synonymous_variant 0.76 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.76 isoniazid
kasA 2518705 c.591T>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.93 isoniazid
kasA 2518765 c.651G>C synonymous_variant 0.91 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.91 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.91 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 1.0 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.91 isoniazid
kasA 2518795 c.681C>T synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>A synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.89 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.88 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.89 isoniazid
kasA 2518879 c.765A>G synonymous_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518898 c.784T>C synonymous_variant 1.0 isoniazid
folC 2747317 c.282C>G synonymous_variant 0.9 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.92 para-aminosalicylic_acid
folC 2747350 c.249C>T synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.91 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.9 para-aminosalicylic_acid
folC 2747392 p.Ile69Val missense_variant 0.64 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782450 c.1593C>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782510 c.1533G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.89 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>A synonymous_variant 0.89 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.97 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783155 c.888C>G synonymous_variant 0.97 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783181 c.862C>T synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 1.0 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783244 p.Thr267Ala missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.84 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783341 c.702C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.75 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.96 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783770 c.273G>A synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783773 c.270A>G synonymous_variant 0.68 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783809 c.234G>A synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783839 c.204C>A synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783851 c.192G>A synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>G synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783944 c.99G>A synonymous_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066003 c.189C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066039 p.Gly51Thr missense_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066045 c.147T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067262 c.684C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067271 c.675G>A synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067277 c.669C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067280 c.666G>C synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 1.0 para-aminosalicylic_acid
thyX 3067287 p.Ala220Val missense_variant 0.83 para-aminosalicylic_acid
thyX 3067293 p.Gln218Arg missense_variant 0.85 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067310 c.636C>G synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067643 c.303C>T synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067658 c.288C>T synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067673 c.273C>T synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067702 p.Ile82Val missense_variant 0.54 para-aminosalicylic_acid
thyX 3067709 c.237G>C synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067748 p.Asp66Glu missense_variant 0.39 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.56 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.75 para-aminosalicylic_acid
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625592 p.Ser341Asn missense_variant 0.75 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625624 c.-714C>A upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625627 c.-717C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625630 c.-722_-720delCTCinsTTG upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3625633 c.981C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.6 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3625759 c.-849G>A upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrB 3625762 c.852A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625798 c.-888G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626750 c.-137T>C upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.78 rifampicin
bedaquiline
mtrA 3626887 c.459_462delGTTG frameshift_variant 1.0 rifampicin
bedaquiline
mtrA 3626894 c.455_456insTTTC frameshift_variant 0.59 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626918 c.432G>A synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626927 c.-314G>C upstream_gene_variant 0.59 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626939 p.Glu137Asp missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626957 c.-344G>T upstream_gene_variant 0.49 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3626992 c.-379C>T upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrB 3626999 c.-386G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.97 rifampicin
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627203 c.-590C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.97 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.78 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
rpoA 3877572 c.936G>C synonymous_variant 0.85 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 1.0 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877931 p.Ile193Val missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 0.46 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>A synonymous_variant 0.75 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>G synonymous_variant 1.0 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 1.0 rifampicin
rpoA 3878049 c.459G>C synonymous_variant 0.72 rifampicin
rpoA 3878052 c.456C>T synonymous_variant 0.72 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.78 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.74 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.78 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.79 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.75 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 0.9 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 1.0 rifampicin
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878998 c.-491C>G upstream_gene_variant 0.43 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 1.0 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>T upstream_gene_variant 0.75 rifampicin
rpoA 3879050 c.-543A>C upstream_gene_variant 0.53 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.6 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.63 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879199 c.-692C>G upstream_gene_variant 0.4 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
clpC1 4038212 c.2493T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038239 c.2466T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038255 p.Val817Thr missense_variant 0.58 pyrazinamide
clpC1 4038257 c.2448G>C synonymous_variant 0.58 pyrazinamide
clpC1 4038260 p.Asp815Glu missense_variant 0.58 pyrazinamide
clpC1 4038266 c.2439C>G synonymous_variant 0.42 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.42 pyrazinamide
clpC1 4038272 p.Gly811Ser missense_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 p.Val799Ile missense_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.33 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.67 pyrazinamide
clpC1 4038335 c.2370C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.36 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038374 c.2331C>A synonymous_variant 0.55 pyrazinamide
clpC1 4038386 c.2317_2319delTTGinsCTA synonymous_variant 0.53 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038440 c.2265C>G synonymous_variant 0.77 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038454 p.Leu751Met missense_variant 0.77 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038461 c.2244G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038482 c.2223G>A synonymous_variant 0.42 pyrazinamide
clpC1 4038485 p.Gly740Thr missense_variant 0.41 pyrazinamide
clpC1 4038488 c.2217C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.59 pyrazinamide
clpC1 4038498 p.Ser736Asn missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.64 pyrazinamide
clpC1 4038533 p.Arg724Lys missense_variant 0.64 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.36 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.46 pyrazinamide
clpC1 4038641 c.2064C>T synonymous_variant 0.44 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038659 p.Ser682Thr missense_variant 0.61 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038674 c.2031C>G synonymous_variant 0.52 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038693 p.Ser671Gly missense_variant 0.48 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.52 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.52 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.52 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.85 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039040 c.1665C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039043 c.1662G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.71 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039253 c.1452C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 p.Ala459Gly missense_variant 0.92 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.95 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 1.0 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.73 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040284 c.421C>T synonymous_variant 0.82 pyrazinamide
clpC1 4040315 c.390G>A synonymous_variant 0.77 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.77 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.83 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 0.82 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040372 c.333C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
panD 4044120 c.162A>G synonymous_variant 1.0 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 1.0 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 1.0 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044162 c.120A>G synonymous_variant 1.0 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 1.0 pyrazinamide
panD 4044174 c.108C>G synonymous_variant 1.0 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 1.0 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.9 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044743 c.-462C>T upstream_gene_variant 0.9 pyrazinamide
panD 4044746 c.-467_-465delGTGinsATC upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 1.0 pyrazinamide
panD 4044785 c.-504C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044794 c.-513G>C upstream_gene_variant 0.84 pyrazinamide
panD 4044812 c.-531A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044815 c.-534G>A upstream_gene_variant 0.83 pyrazinamide
panD 4044818 c.-539_-537delCCGinsGCC upstream_gene_variant 0.83 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.8 pyrazinamide
panD 4044836 c.-555C>G upstream_gene_variant 0.8 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.74 pyrazinamide
panD 4044848 c.-567T>C upstream_gene_variant 0.72 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044965 c.-684T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 1.0 pyrazinamide
glpK 4138568 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4240954 p.Ile364Met missense_variant 1.0 ethambutol
embC 4240961 c.1099C>T synonymous_variant 0.91 ethambutol
embC 4241013 p.Met384Thr missense_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>C synonymous_variant 1.0 ethambutol
embC 4241032 c.1170G>T synonymous_variant 0.84 ethambutol
embC 4241038 c.1176G>C synonymous_variant 1.0 ethambutol
embC 4241044 c.1182C>T synonymous_variant 0.88 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241158 c.1296T>C synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241188 c.1326C>T synonymous_variant 1.0 ethambutol
embC 4241227 c.1365G>A synonymous_variant 1.0 ethambutol
embC 4241228 c.1366_1368delCTAinsTTG synonymous_variant 1.0 ethambutol
embC 4241248 c.1386G>C synonymous_variant 1.0 ethambutol
embC 4241251 c.1389T>C synonymous_variant 1.0 ethambutol
embC 4241256 p.Arg465Thr missense_variant 1.0 ethambutol Uncertain significance
embC 4241268 p.Val469Ala missense_variant 1.0 ethambutol
embC 4241272 c.1410A>G synonymous_variant 1.0 ethambutol
embC 4241275 c.1413A>G synonymous_variant 1.0 ethambutol
embC 4241518 c.1656A>G synonymous_variant 1.0 ethambutol
embC 4241521 c.1659T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241536 c.1674A>G synonymous_variant 1.0 ethambutol
embC 4241539 c.1677T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241548 c.1686T>C synonymous_variant 1.0 ethambutol
embC 4241567 p.Ile569Val missense_variant 1.0 ethambutol
embC 4241578 c.1716G>C synonymous_variant 1.0 ethambutol
embC 4241584 c.1722T>C synonymous_variant 1.0 ethambutol
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245137 c.1905T>C synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247857 c.1344C>G synonymous_variant 1.0 ethambutol
embB 4247881 c.1368G>C synonymous_variant 1.0 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247905 c.1392G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248118 c.1605T>G synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248146 p.Ile545Val missense_variant 0.73 ethambutol
embB 4248149 p.Thr546Ala missense_variant 0.73 ethambutol Uncertain significance
embB 4248154 c.1641G>A synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4248157 c.1644A>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>C synonymous_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 0.84 ethambutol
embB 4248199 c.1686A>G synonymous_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248211 c.1698G>C synonymous_variant 0.83 ethambutol
embB 4248214 c.1701C>G synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim