TB-Profiler result

Run: ERR323037

Summary

Run ID: ERR323037

Sample name:

Date: 2024-04-16T02:17:04.102139

Number of reads: 173579

Percentage reads mapped: 3.5

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin gyrA p.Ser91Ala Mutation from literature
ofloxacin
levofloxacin gyrA p.Ser91Ala Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.760_762delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrA 7572 p.Ser91Ala missense_variant 1.0 levofloxacin Mutation from literature
moxifloxacin Mutation from literature
fgd1 491542 c.760_762delTTGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 888 c.888C>G synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 904 p.Ile302Val missense_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 915 c.915C>T synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 933 c.933C>G synonymous_variant 1.0 isoniazid
dnaA 939 c.939C>G synonymous_variant 1.0 isoniazid
gyrB 6133 c.894G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6326 p.Ser363Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6889 c.-413G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7366 p.Gln22Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7377 p.Arg26Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7445 c.144C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7569 p.Ala90Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7611 p.Ser104Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7614 p.Leu105Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7619 c.318C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8294 c.993T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8843 c.1542G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8909 c.1608C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9208 p.Lys636Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9234 c.1933_1935delTCGinsAGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9254 c.1953C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9257 c.1956C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9267 c.1966_1968delAACinsGG frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9276 c.1975C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491532 c.750G>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491569 p.Asp263Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491590 p.Lys270Ala missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 1.0 isoniazid
hadA 731760 c.-170_-169delGTinsCA upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.94 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.94 isoniazid
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734476 c.223_225delGTCinsTG frameshift_variant&missense_variant 0.94 rifampicin
nusG 734480 p.Gly76Glu missense_variant 0.94 rifampicin
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>G synonymous_variant 0.95 rifampicin
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734550 p.Gln99His missense_variant 0.94 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760175 c.369C>T synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760185 c.379C>T synonymous_variant 1.0 rifampicin
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 1.0 rifampicin Uncertain significance
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>G synonymous_variant 0.85 rifampicin
rpoB 760522 p.Ser239Thr missense_variant 0.93 rifampicin
rpoB 760527 p.Gln241Glu missense_variant 0.94 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760571 c.765G>C synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760595 c.789C>T synonymous_variant 1.0 rifampicin
rpoB 760596 p.Thr264Gln missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760640 c.834C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760652 c.846C>G synonymous_variant 0.73 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 1.0 rifampicin
rpoB 760721 c.915C>G synonymous_variant 0.58 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.91 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.92 rifampicin Uncertain significance
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.74 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.74 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761162 c.1356G>C synonymous_variant 0.96 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.92 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>T synonymous_variant 1.0 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.98 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 1.0 rifampicin
rpoB 761341 p.Lys512Arg missense_variant 0.88 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761521 p.Tyr572Phe missense_variant 0.82 rifampicin
rpoB 761528 c.1722C>T synonymous_variant 0.35 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>T synonymous_variant 0.36 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.96 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761643 p.Val613Ile missense_variant 0.93 rifampicin Uncertain significance
rpoB 761972 c.2166C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762002 c.2196C>G synonymous_variant 1.0 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762009 c.2203C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762018 p.Glu738Gln missense_variant 1.0 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762041 c.2235C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762068 c.2262C>T synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762089 c.2283G>A synonymous_variant 1.0 rifampicin
rpoB 762113 c.2307C>T synonymous_variant 1.0 rifampicin
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.4 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762170 c.2364C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>G synonymous_variant 1.0 rifampicin
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762200 c.2394C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.46 rifampicin
rpoB 762249 c.2443C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>G synonymous_variant 1.0 rifampicin
rpoB 762287 c.2481C>G synonymous_variant 0.99 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.99 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762335 c.2529C>T synonymous_variant 1.0 rifampicin
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762353 c.2547C>G synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762368 p.Glu854Asp missense_variant 0.5 rifampicin
rpoB 762368 p.Glu854Asp missense_variant 0.5 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoB 762375 c.2569_2571delGCCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762398 c.-972T>G upstream_gene_variant 1.0 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762426 p.Ser874Gln missense_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoC 762446 c.-924C>G upstream_gene_variant 1.0 rifampicin
rpoC 762467 c.-903C>T upstream_gene_variant 0.97 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Thr missense_variant 0.82 rifampicin
rpoC 762512 c.-858C>G upstream_gene_variant 0.6 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762858 p.Thr1018Ala missense_variant 1.0 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762866 c.3060C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.99 rifampicin
rpoB 762989 c.3183G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763049 c.-321G>A upstream_gene_variant 0.98 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 1.0 rifampicin
rpoB 763082 c.3276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763100 c.-270G>A upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoB 763145 c.3339G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763157 c.-213G>C upstream_gene_variant 0.98 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763196 c.-174G>A upstream_gene_variant 0.95 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.97 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.97 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.97 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763259 c.-111G>C upstream_gene_variant 0.94 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 0.96 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.96 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.95 rifampicin
rpoC 763420 c.51G>C synonymous_variant 0.96 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.96 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.96 rifampicin
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763453 c.84C>G synonymous_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>T synonymous_variant 1.0 rifampicin
rpoC 763531 c.162G>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 1.0 rifampicin
rpoC 763537 c.168C>G synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763642 c.273G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763778 p.Thr137Val missense_variant 1.0 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763796 p.Met143Leu missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763930 c.561G>A synonymous_variant 1.0 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763978 c.609C>T synonymous_variant 0.95 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764053 c.684G>A synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764134 c.765C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764164 p.Ile265Met missense_variant 1.0 rifampicin
rpoC 764169 p.Asn267Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 764182 p.Asp271Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764207 p.Val280Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764217 p.Asn283Thr missense_variant 1.0 rifampicin
rpoC 764227 c.858G>C synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.97 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.96 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.96 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.96 rifampicin
rpoC 764274 c.908_909insGGCCA frameshift_variant 0.95 rifampicin
rpoC 764279 c.911_915delAGTCG frameshift_variant 0.88 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.91 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.96 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.93 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.95 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.95 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.9 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764509 c.1140G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.99 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.98 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.98 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>G synonymous_variant 0.98 rifampicin
rpoC 764809 c.1440C>G synonymous_variant 0.98 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.96 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764848 c.1479G>A synonymous_variant 0.98 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.95 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765481 c.2112C>T synonymous_variant 0.9 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765544 c.2175C>G synonymous_variant 0.95 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2180delAGinsTC synonymous_variant 0.95 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.95 rifampicin
rpoC 765569 p.Ala734Ser missense_variant 0.94 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.92 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>T synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765820 c.2451G>C synonymous_variant 1.0 rifampicin
rpoC 765844 c.2475C>G synonymous_variant 1.0 rifampicin
rpoC 765871 c.2502T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765907 c.2538G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.98 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.98 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.97 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766429 c.3061_3062insCTG disruptive_inframe_insertion 1.0 rifampicin
rpoC 766435 p.Glu1022Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766612 c.3243C>G synonymous_variant 1.0 rifampicin
rpoC 766624 c.3255G>T synonymous_variant 1.0 rifampicin
rpoC 766645 p.Glu1092Asp missense_variant 1.0 rifampicin Not assoc w R
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766660 c.3291G>C synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766799 c.3430_3432delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767060 c.3691_3693delCGCinsAG frameshift_variant&missense_variant 0.95 rifampicin
rpoC 767065 c.3696G>T synonymous_variant 0.96 rifampicin
rpoC 767071 c.3702C>G synonymous_variant 0.96 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 1.0 rifampicin
rpoC 767093 c.3724_3725delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Ile missense_variant 1.0 rifampicin
rpoC 767110 c.3741T>C synonymous_variant 1.0 rifampicin
rpoC 767113 c.3744G>C synonymous_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpsL 781760 c.201T>C synonymous_variant 0.83 streptomycin
rpsL 781763 c.204C>G synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>G synonymous_variant 1.0 streptomycin
rpsL 781793 c.234G>C synonymous_variant 1.0 streptomycin
rpsL 781802 c.243G>C synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>T synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781853 c.294C>T synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800672 c.-137G>C upstream_gene_variant 0.86 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.89 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>C upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106_-104delTTGinsCT upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>G upstream_gene_variant 0.95 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304599 p.Ile557Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
rrs 1471914 n.69A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471943 n.98T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471978 n.133C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472070 n.225G>A non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472971 n.1126G>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.98 streptomycin Not assoc w R
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473812 n.155G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172_175delGTGCinsCGGTG non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474265 n.608G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.630dupT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474293 n.637_646delCCTCTCCGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474350 n.693G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474664 n.1007G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474666 n.1009T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474670 n.1013C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474679 n.1022G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474684 n.1027T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474687 n.1030C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474716 n.1059_1060delAAinsGAG non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475109 n.1452C>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475422 n.1765A>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475481 n.1824C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475735 n.2078T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475760 n.2103C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475762 n.2105G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475765 n.2108A>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475769 n.2113_2114insCG non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833646 c.105T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833734 c.193_195delGCCinsTT frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833739 c.198C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833877 c.336C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 1.0 pyrazinamide
rpsA 1834090 c.549G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.97 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834307 p.Asp256Asn missense_variant 0.96 pyrazinamide
rpsA 1834340 p.Met267Leu missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834399 p.His286Gln missense_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834552 c.1011G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.95 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834649 p.Thr370His missense_variant 0.96 pyrazinamide
rpsA 1834653 p.Glu371Ala missense_variant 0.95 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.96 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 1.0 pyrazinamide
rpsA 1834738 p.Glu399Asp missense_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834788 p.Ala416Gly missense_variant 0.92 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834804 c.1263C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 0.9 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853372 c.-234A>G upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853393 c.-213C>G upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212C>A upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.96 linezolid
tsnR 1853418 c.-188_-186delCTTinsTC upstream_gene_variant 0.96 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 1.0 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 1.0 linezolid
kasA 2517917 c.-198G>T upstream_gene_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>T upstream_gene_variant 1.0 isoniazid
kasA 2518745 p.Ser211Thr missense_variant 0.91 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.92 isoniazid
kasA 2518763 c.649_651delTCGinsAGC synonymous_variant 0.92 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>G synonymous_variant 1.0 isoniazid
kasA 2518784 p.Glu224Lys missense_variant 1.0 isoniazid
kasA 2518787 c.673_675delCGGinsGC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518828 c.714G>C synonymous_variant 1.0 isoniazid
ahpC 2726582 c.390G>C synonymous_variant 1.0 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726604 p.Val138Ile missense_variant 1.0 isoniazid
ahpC 2726612 c.420C>G synonymous_variant 1.0 isoniazid
ahpC 2726636 c.444G>C synonymous_variant 1.0 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>T synonymous_variant 1.0 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
Rv2477c 2782465 c.1578G>A synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ser missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.91 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782522 c.1521G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782561 c.1482G>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782582 p.Asn487Lys missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782586 p.Leu486Glu missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782606 c.1437T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782609 c.1434G>C synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782612 c.1431T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782624 c.1419G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782645 c.1398C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783365 c.678C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.670_672delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783632 c.411C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783653 c.390C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 p.Glu128Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783672 p.Arg124Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783692 c.351G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625681 c.-771G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625695 c.-785C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625726 c.-816G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625741 c.-831G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 p.Arg284Asn missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625783 p.Asp277Glu missense_variant 0.94 bedaquiline
rifampicin
mtrB 3625794 p.Ser274Ala missense_variant 0.92 bedaquiline
rifampicin
mtrB 3625796 p.Val273Gln missense_variant 0.91 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626804 c.-191A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626810 c.-197A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626819 c.-206G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626822 p.Asp176Glu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626828 c.-215T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626831 c.-218T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626852 c.-239G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627038 c.310_312delATGinsGC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627047 c.-434C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627053 c.-440C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627077 c.-464G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627086 c.-473C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627098 c.-485A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627101 c.-488C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627122 c.-509T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627134 c.-521C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627143 c.-530G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.88 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.89 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877650 c.858C>T synonymous_variant 0.97 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 1.0 rifampicin
rpoA 3877665 c.843C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877734 c.774G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.95 rifampicin
rpoA 3877764 p.Ala248Gly missense_variant 1.0 rifampicin
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 1.0 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877893 c.615C>G synonymous_variant 0.95 rifampicin
rpoA 3877898 p.Pro204Ala missense_variant 0.88 rifampicin
rpoA 3877905 c.603A>C synonymous_variant 1.0 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877932 c.576G>C synonymous_variant 0.95 rifampicin
rpoA 3877936 p.Lys191Arg missense_variant 0.95 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 1.0 rifampicin
rpoA 3877965 c.543C>T synonymous_variant 0.96 rifampicin
rpoA 3877968 c.540C>G synonymous_variant 0.96 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 1.0 rifampicin
rpoA 3878102 p.Val136Ile missense_variant 0.7 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-574_-572delGTAinsAC upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2311_2313delCGCinsAG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038407 c.2298G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038539 c.2166G>C synonymous_variant 0.92 pyrazinamide
clpC1 4038557 c.2146_2148delATCinsGG frameshift_variant&missense_variant 0.94 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.93 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 0.91 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.92 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.92 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039427 p.Glu426Asp missense_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039574 c.1131G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039634 c.1069_1071delGAGinsAC frameshift_variant&missense_variant 0.98 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039694 c.1011G>T synonymous_variant 0.98 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.94 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039844 c.861C>T synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.97 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.97 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040002 p.His235Asn missense_variant 0.97 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040124 p.Glu194Ser missense_variant 1.0 pyrazinamide
clpC1 4040426 c.279T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040429 c.274_276delTTGinsCT frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040516 c.189C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040539 c.166C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040543 c.162C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040549 c.154_156delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide