Run ID: SRR29096410
Sample name:
Date: 2024-09-26T12:58:04.046276
Number of reads: 324770
Percentage reads mapped: 56.02
Median coverage: 4.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: RR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage3.1.2.2 | East-African-Indian | RD750 | 0.12 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.87 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| isoniazid | ||||
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| p.Tyr384Asn | Mutation from literature | |||
| p.Asn399Asp | Mutation from literature | |||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fbiC | c.532_534delGCAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.550_552delCAAinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.799_801delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.820_822delTTAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 0.85 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| fbiC | 1303462 | c.532_534delGCAinsTG | frameshift_variant&stop_gained | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303480 | c.550_552delCAAinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303729 | c.799_801delCTAinsTG | frameshift_variant&stop_gained | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303750 | c.820_822delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| embB | 4247580 | p.Ala356Val | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| embB | 4247663 | p.Tyr384Asn | missense_variant | 0.95 | ethambutol | Mutation from literature | |
| embB | 4247708 | p.Asn399Asp | missense_variant | 0.94 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 6172 | c.933C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6190 | c.951A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6265 | c.1026C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6298 | c.1059C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6299 | c.1060C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6316 | c.-986G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6911 | p.Asn558His | missense_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6970 | c.-332C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6985 | c.-317C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6997 | c.-305G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7000 | c.-302C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7003 | c.-299C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7030 | c.-272C>G | upstream_gene_variant | 0.47 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7048 | c.-254G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>T | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.83 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 0.82 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 0.8 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8535 | p.Glu412Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8543 | c.1242C>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8555 | c.1254G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8585 | c.1284C>T | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>T | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8627 | c.1326C>A | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8694 | c.1393C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8717 | c.1416C>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8720 | c.1419G>A | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8765 | p.Asp488Glu | missense_variant | 0.96 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 0.96 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8779 | p.Asp493Ala | missense_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8789 | c.1488C>T | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8792 | c.1491G>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8798 | c.1497C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 0.96 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 0.96 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8840 | c.1539C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8888 | c.1587C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8924 | c.1623C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8930 | c.1629C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8933 | c.1632G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8936 | c.1635G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8983 | p.Cys561Ser | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9003 | c.1702C>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>A | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9038 | c.1737C>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 0.93 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9062 | c.1761C>A | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9074 | c.1773G>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9101 | c.1800A>G | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9104 | c.1803C>A | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9110 | c.1809G>A | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9128 | c.1827C>A | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9147 | p.Gly616Ser | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9164 | c.1863G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9183 | p.Arg628Lys | missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9248 | c.1947G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9266 | c.1965C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9287 | c.1986G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9291 | c.1990C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9315 | c.2014C>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9326 | c.2025G>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9338 | c.2037G>A | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9398 | c.2097T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| mshA | 574607 | c.-741G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574610 | c.-738G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574616 | c.-732G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574640 | c.-708G>A | upstream_gene_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 574646 | c.-702G>A | upstream_gene_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 574667 | c.-681G>A | upstream_gene_variant | 0.81 | ethionamide | |
| isoniazid | ||||||
| mshA | 574673 | c.-675A>G | upstream_gene_variant | 0.79 | ethionamide | |
| isoniazid | ||||||
| mshA | 574676 | c.-672G>C | upstream_gene_variant | 0.79 | ethionamide | |
| isoniazid | ||||||
| mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.79 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 0.79 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574694 | c.-654C>G | upstream_gene_variant | 0.79 | ethionamide | |
| isoniazid | ||||||
| mshA | 574712 | c.-636A>G | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574721 | c.-627C>A | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574724 | c.-624T>C | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574727 | c.-621G>C | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574731 | c.-617A>G | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574739 | c.-609T>C | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 575665 | c.318G>C | synonymous_variant | 0.92 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575695 | c.348C>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575704 | c.357T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 0.97 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575767 | c.420G>A | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | p.Glu144Asp | missense_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575780 | c.433_435delCCGinsGC | frameshift_variant&missense_variant | 0.96 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575845 | c.498C>G | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 575848 | c.501C>T | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575851 | c.504C>G | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619507 | c.-384A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619516 | c.-375C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619525 | c.-366C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619531 | c.-360T>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619534 | c.-357G>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619537 | c.-354A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619540 | c.-351C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619543 | c.-348C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619544 | c.-347A>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619552 | c.-339A>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619555 | c.-336C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619561 | c.-330G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619564 | c.-327C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619570 | c.-321G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619573 | c.-318G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619574 | c.-317G>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619579 | c.-312G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619588 | c.-303C>G | upstream_gene_variant | 0.88 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.88 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619594 | c.-297G>A | upstream_gene_variant | 0.88 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619624 | c.-267C>T | upstream_gene_variant | 0.83 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620197 | p.Gln103Met | missense_variant | 0.91 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620238 | c.348G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620253 | c.363G>C | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620271 | c.381C>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | c.394_396delGCGinsCA | frameshift_variant&missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620291 | p.Tyr134Phe | missense_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620307 | c.417C>G | synonymous_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.85 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620325 | c.435G>C | synonymous_variant | 0.87 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620343 | c.453G>C | synonymous_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620349 | c.459A>T | synonymous_variant | 0.88 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 0.75 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 0.75 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 0.73 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620376 | c.486G>C | synonymous_variant | 0.73 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>C | synonymous_variant | 0.73 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620389 | c.499C>T | synonymous_variant | 0.73 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620394 | c.504G>A | synonymous_variant | 0.73 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620400 | c.510C>T | synonymous_variant | 0.73 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620569 | c.679_681delGGAinsCC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620589 | c.699G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620613 | c.723C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620631 | c.741T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620712 | c.822G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620715 | c.825C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620781 | c.891C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620783 | p.Ala298Val | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620787 | c.897C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620796 | c.906C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620829 | c.939G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620835 | c.945C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620844 | c.954C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620853 | c.963G>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| Rv0565c | 657183 | c.288G>A | synonymous_variant | 0.94 | ethionamide | |
| Rv0565c | 657189 | c.282C>A | synonymous_variant | 0.95 | ethionamide | |
| Rv0565c | 657193 | p.Met93Thr | missense_variant | 0.95 | ethionamide | |
| Rv0565c | 657196 | p.Asp92Ala | missense_variant | 0.95 | ethionamide | |
| Rv0565c | 657200 | p.Thr91Ala | missense_variant | 0.95 | ethionamide | Uncertain significance |
| Rv0565c | 657210 | c.261C>T | synonymous_variant | 0.95 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 657213 | c.258C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657219 | p.Ala84Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657233 | p.Ile80Val | missense_variant | 0.96 | ethionamide | |
| Rv0565c | 657240 | c.229_231delGAAinsAG | frameshift_variant&synonymous_variant | 0.96 | ethionamide | Uncertain significance |
| Rv0565c | 657252 | c.219G>C | synonymous_variant | 0.96 | ethionamide | |
| Rv0565c | 657255 | c.216G>A | synonymous_variant | 0.96 | ethionamide | |
| Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.96 | ethionamide | |
| Rv0565c | 657294 | c.177C>A | synonymous_variant | 0.92 | ethionamide | |
| Rv0565c | 657306 | c.165C>T | synonymous_variant | 0.9 | ethionamide | |
| Rv0565c | 657312 | c.159C>T | synonymous_variant | 0.88 | ethionamide | |
| Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.83 | ethionamide | |
| Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.82 | ethionamide | |
| Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 0.75 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.81 | ethionamide | |
| Rv0565c | 657695 | c.-225C>G | upstream_gene_variant | 0.81 | ethionamide | |
| Rv0565c | 657725 | c.-255G>A | upstream_gene_variant | 0.89 | ethionamide | |
| Rv0565c | 657732 | c.-263_-262delAGinsGA | upstream_gene_variant | 0.84 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.84 | ethionamide | |
| hadA | 731686 | c.-244_-243insATGT | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731689 | c.-240_-237delAGAC | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731695 | c.-235C>T | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731698 | c.-232T>G | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731708 | c.-222G>A | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731711 | c.-219T>C | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731726 | c.-204C>G | upstream_gene_variant | 0.94 | isoniazid | |
| hadA | 731729 | c.-201C>T | upstream_gene_variant | 0.94 | isoniazid | |
| hadA | 731753 | c.-177A>C | upstream_gene_variant | 0.92 | isoniazid | |
| hadA | 731756 | c.-174C>T | upstream_gene_variant | 0.92 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.89 | isoniazid | |
| hadA | 731786 | c.-144C>G | upstream_gene_variant | 0.84 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.81 | isoniazid | |
| hadA | 732329 | p.Leu134Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.91 | rifampicin | Uncertain significance |
| nusG | 734093 | c.-161A>G | upstream_gene_variant | 0.91 | rifampicin | |
| nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.92 | rifampicin | |
| nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.92 | rifampicin | |
| nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734142 | c.-112_-110delGCGinsATA | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734150 | c.-104G>C | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734153 | c.-101C>A | upstream_gene_variant | 0.95 | rifampicin | |
| nusG | 734171 | c.-83_-82insG | upstream_gene_variant | 0.95 | rifampicin | |
| nusG | 734175 | c.-79G>T | upstream_gene_variant | 0.95 | rifampicin | |
| nusG | 734177 | c.-76delG | upstream_gene_variant | 0.95 | rifampicin | |
| nusG | 734183 | c.-71C>T | upstream_gene_variant | 0.95 | rifampicin | |
| nusG | 734186 | c.-68G>C | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| nusG | 734203 | c.-51_-50delTGinsCC | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734205 | c.-49A>C | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734208 | c.-46T>C | upstream_gene_variant | 0.94 | rifampicin | |
| nusG | 734224 | c.-30G>C | upstream_gene_variant | 0.9 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 0.93 | rifampicin | |
| nusG | 734424 | c.171G>C | synonymous_variant | 0.93 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 0.89 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 0.89 | rifampicin | |
| nusG | 734472 | c.219T>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| nusG | 734475 | c.222T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| nusG | 734478 | c.225C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| nusG | 734499 | c.246G>C | synonymous_variant | 0.9 | rifampicin | |
| nusG | 734520 | c.267C>A | synonymous_variant | 0.88 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| nusG | 734814 | c.561G>C | synonymous_variant | 0.69 | rifampicin | |
| nusG | 734820 | c.567A>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| nusG | 734826 | c.573A>G | synonymous_variant | 0.71 | rifampicin | |
| nusG | 734829 | c.576C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
| nusG | 734841 | c.588G>T | synonymous_variant | 0.71 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 0.77 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 0.77 | rifampicin | |
| nusG | 734870 | p.Ser206Asn | missense_variant | 0.67 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 0.71 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 0.71 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 0.71 | rifampicin | |
| nusG | 734931 | c.678A>T | synonymous_variant | 0.71 | rifampicin | |
| nusG | 734940 | c.687G>A | synonymous_variant | 0.64 | rifampicin | |
| nusG | 734943 | c.690G>C | synonymous_variant | 0.6 | rifampicin | |
| rpoB | 760043 | c.237C>T | synonymous_variant | 0.82 | rifampicin | |
| rpoB | 760046 | c.240G>C | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 760056 | c.250_252delCTCinsTG | frameshift_variant&missense_variant | 0.85 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 0.89 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760109 | c.303C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760145 | c.339C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760181 | c.375T>A | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760244 | c.438G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760845 | c.1039_1041delACCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 760856 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760937 | c.1131G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760973 | c.1167G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760982 | c.1176G>T | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760985 | c.1179G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760991 | c.1185G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761006 | c.1200C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761192 | c.1386C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761240 | c.1434C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>T | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 0.95 | rifampicin | |
| rpoB | 761374 | p.Val523Glu | missense_variant | 0.96 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 0.81 | rifampicin | |
| rpoB | 761432 | c.1626C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 0.77 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 0.77 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 0.77 | rifampicin | |
| rpoB | 761452 | p.Val549Glu | missense_variant | 0.75 | rifampicin | |
| rpoB | 761457 | p.Pro551Ser | missense_variant | 0.75 | rifampicin | |
| rpoB | 761465 | c.1659G>A | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
| rpoB | 761471 | c.1665C>T | synonymous_variant | 0.77 | rifampicin | |
| rpoB | 761477 | c.1671C>T | synonymous_variant | 0.77 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 0.73 | rifampicin | |
| rpoB | 761504 | c.1698C>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 0.86 | rifampicin | |
| rpoB | 761531 | c.1725C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 0.96 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 0.96 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 0.96 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761828 | c.2022C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761837 | c.2031C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761913 | c.2107_2109delGACinsCA | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 0.93 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 762134 | c.2328C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762233 | c.2427G>T | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 762281 | c.2475G>A | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762431 | c.2625C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.92 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.92 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 762710 | c.-660G>T | upstream_gene_variant | 0.83 | rifampicin | |
| rpoB | 762729 | p.Gln975Lys | missense_variant | 0.86 | rifampicin | |
| rpoB | 762736 | p.Ala977Glu | missense_variant | 0.86 | rifampicin | |
| rpoB | 762749 | c.2943C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoB | 762753 | c.2947T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoC | 762776 | c.-594C>G | upstream_gene_variant | 0.8 | rifampicin | |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 0.8 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.8 | rifampicin | |
| rpoB | 762795 | p.Asp997Asn | missense_variant | 0.8 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Val | missense_variant | 0.8 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 762833 | c.3027C>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoC | 762902 | c.-468C>T | upstream_gene_variant | 0.9 | rifampicin | |
| rpoC | 762917 | c.-453C>T | upstream_gene_variant | 0.91 | rifampicin | |
| rpoB | 762929 | c.3123G>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 762983 | c.-387C>G | upstream_gene_variant | 0.95 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763050 | c.-320C>T | upstream_gene_variant | 0.98 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763082 | c.3276C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.81 | rifampicin | |
| rpoC | 763205 | c.-165G>T | upstream_gene_variant | 0.81 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.81 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.8 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
| rpoC | 763241 | c.-129G>A | upstream_gene_variant | 0.75 | rifampicin | |
| rpoC | 763250 | c.-120C>T | upstream_gene_variant | 0.75 | rifampicin | |
| rpoC | 763253 | c.-117G>T | upstream_gene_variant | 0.75 | rifampicin | |
| rpoC | 763262 | c.-108C>A | upstream_gene_variant | 0.82 | rifampicin | |
| rpoC | 763265 | c.-105G>A | upstream_gene_variant | 0.8 | rifampicin | |
| rpoC | 763402 | c.33C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763409 | c.40_42delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763414 | c.45T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763726 | c.357C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 763771 | c.402C>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 763780 | c.411C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 0.92 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763836 | p.Ala156Val | missense_variant | 0.95 | rifampicin | |
| rpoC | 763851 | p.Ala161Gly | missense_variant | 0.94 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763936 | c.567C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763951 | c.582G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763963 | c.594C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763967 | p.Gly200Ser | missense_variant | 0.98 | rifampicin | |
| rpoC | 763972 | c.603C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763987 | c.618C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764011 | c.642T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 0.91 | rifampicin | |
| rpoC | 764044 | c.675T>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764140 | c.771C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764159 | c.790C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764167 | c.798G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 0.92 | rifampicin | |
| rpoC | 764215 | c.846A>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764218 | c.849C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764242 | c.873C>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 764245 | c.876C>A | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764246 | c.877_879delCTCinsTG | frameshift_variant&missense_variant | 0.94 | rifampicin | |
| rpoC | 764263 | c.894G>C | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 0.89 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 0.85 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 0.85 | rifampicin | |
| rpoC | 764605 | c.1236G>A | synonymous_variant | 0.88 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 0.95 | rifampicin | |
| rpoC | 764896 | c.1527C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764902 | c.1533C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765013 | c.1644C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 765053 | c.1684_1686delTCCinsAGT | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765065 | c.1696C>T | synonymous_variant | 0.87 | rifampicin | |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 0.87 | rifampicin | |
| rpoC | 765079 | c.1710T>C | synonymous_variant | 0.87 | rifampicin | |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>A | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoC | 765121 | c.1752G>T | synonymous_variant | 0.85 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoC | 765328 | p.His653Gln | missense_variant | 0.87 | rifampicin | Uncertain significance |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 0.87 | rifampicin | Uncertain significance |
| rpoC | 765334 | c.1965C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765343 | c.1974G>A | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765367 | c.1998C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 765370 | c.2001G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 0.9 | rifampicin | Uncertain significance |
| rpoC | 765578 | c.2209C>T | synonymous_variant | 0.87 | rifampicin | |
| rpoC | 765622 | p.Glu751Asp | missense_variant | 0.8 | rifampicin | |
| rpoC | 765625 | c.2256C>T | synonymous_variant | 0.8 | rifampicin | |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 0.9 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 765790 | c.2421C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766061 | p.Val898Ile | missense_variant | 0.9 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766369 | c.3000C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766402 | c.3033C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766408 | c.3039C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766486 | c.3117A>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.93 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766660 | c.3291G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766700 | c.3331C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766733 | c.3364C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766741 | c.3372G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766876 | c.3507C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | c.3514_3516delTCGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766996 | c.3627C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767158 | c.3789T>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.94 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775946 | c.2535C>G | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775951 | c.2530C>T | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.85 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.88 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.83 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776030 | c.2451G>T | synonymous_variant | 0.73 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776036 | c.2445G>T | synonymous_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776039 | c.2442C>G | synonymous_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781134 | c.-426T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781138 | c.-422C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781143 | c.-417T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781152 | c.-408G>A | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 0.95 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 0.95 | streptomycin | |
| rpsL | 781616 | c.57C>T | synonymous_variant | 0.95 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 0.95 | streptomycin | Not assoc w R - Interim |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.95 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 0.95 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.95 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 0.9 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 0.91 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781772 | c.213C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781793 | c.234G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781835 | c.276T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781859 | c.300T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781883 | c.324G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781886 | c.327C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 1.0 | streptomycin | |
| rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800582 | c.-227C>T | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.92 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.9 | linezolid | |
| rplC | 800621 | c.-188G>A | upstream_gene_variant | 0.9 | linezolid | |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.89 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.83 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.85 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.91 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.92 | linezolid | |
| rplC | 800714 | c.-95C>T | upstream_gene_variant | 0.91 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.91 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.91 | linezolid | |
| rplC | 800744 | c.-65G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800745 | c.-64_-62delCTCinsTG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303488 | c.558G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303506 | c.576C>T | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303538 | p.Arg203Leu | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303578 | c.648G>A | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303596 | c.666G>C | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303620 | c.690C>T | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303629 | c.699C>T | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303661 | p.Val244Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303686 | c.756C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304459 | p.Thr510Ser | missense_variant | 0.83 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304465 | p.Gly512Asp | missense_variant | 0.83 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304469 | c.1539G>A | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304472 | c.1542T>C | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304478 | c.1548G>C | synonymous_variant | 0.88 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304481 | c.1551T>G | synonymous_variant | 0.82 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304496 | c.1566T>A | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304499 | c.1569T>G | synonymous_variant | 0.95 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304502 | c.1572G>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304526 | c.1596T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304532 | c.1602G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304533 | c.1603T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304541 | c.1611C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304546 | p.Val539Ala | missense_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304610 | c.1680C>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304672 | p.Val581Ala | missense_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304674 | p.Gly582Gln | missense_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.83 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.77 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304797 | p.Ala623Asn | missense_variant | 0.75 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.84 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.85 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304823 | c.1893C>T | synonymous_variant | 0.85 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.86 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.87 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304868 | c.1938G>C | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304871 | c.1941G>T | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304872 | c.1942_1943delAGinsTC | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304875 | p.Ile649Val | missense_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304883 | c.1953G>A | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 0.83 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.83 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.83 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473797 | n.140G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473831 | n.174G>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474018 | n.361G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
| linezolid | ||||||
| rrl | 1474030 | n.373G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
| linezolid | ||||||
| rrl | 1474061 | n.404T>C | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
| linezolid | ||||||
| rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| inhA | 1673565 | c.-637G>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673580 | c.-622T>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673596 | p.Lys53Glu | missense_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673604 | c.-598G>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673615 | p.Glu59Val | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673633 | p.Ser65Asn | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673657 | p.Thr73Lys | missense_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673660 | p.Ala74Glu | missense_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673679 | c.-523T>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1674601 | p.Leu134Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674618 | c.417C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674655 | c.454_456delAGCinsTCG | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674669 | c.468G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674687 | c.486G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674693 | c.492C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674696 | c.495G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674717 | c.516C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674729 | c.528G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674745 | p.Tyr182Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674759 | c.558G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674765 | c.564C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674774 | c.573A>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674777 | c.576C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674792 | c.591G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674820 | c.619_621delCTCinsTG | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674828 | c.627G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674846 | p.Ile215Met | missense_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674876 | c.675C>G | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674888 | c.687C>T | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | c.703_705delGCGinsCC | frameshift_variant&missense_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674909 | c.708G>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674915 | c.714C>G | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674939 | c.738G>A | synonymous_variant | 0.94 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674942 | c.741T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674966 | c.765T>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674967 | p.Asp256Thr | missense_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674993 | c.792G>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674994 | p.His265Ser | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1675006 | c.805_807delCTCinsTG | frameshift_variant&missense_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.95 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833613 | c.72C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833703 | c.162C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833808 | c.267G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833859 | c.318C>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833895 | c.354G>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833964 | c.423C>T | synonymous_variant | 0.94 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833970 | c.429G>A | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834231 | c.690T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834336 | c.795C>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834357 | c.816T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834396 | c.855G>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834477 | c.936C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834519 | c.978G>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834603 | c.1062G>A | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834612 | c.1071G>A | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834654 | c.1113G>A | synonymous_variant | 0.89 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834699 | p.Glu386Asp | missense_variant | 0.95 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1834747 | c.1206A>G | synonymous_variant | 0.89 | pyrazinamide | |
| rpsA | 1834751 | c.1210_1212delCTTinsAG | frameshift_variant&missense_variant | 0.88 | pyrazinamide | Uncertain significance |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>C | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.88 | pyrazinamide | |
| rpsA | 1834766 | p.Lys409Ala | missense_variant | 0.88 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Gln | missense_variant | 0.88 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834813 | c.1272G>T | synonymous_variant | 0.93 | pyrazinamide | |
| tsnR | 1853369 | c.-237C>T | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853393 | c.-213C>T | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.97 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853441 | c.-165C>G | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853450 | c.-156G>A | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853453 | c.-153G>C | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 0.95 | linezolid | |
| tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.94 | linezolid | |
| tsnR | 1853481 | c.-125A>G | upstream_gene_variant | 0.93 | linezolid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.98 | isoniazid | |
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.98 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517965 | c.-150C>T | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517983 | c.-132T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>G | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518025 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518031 | c.-84G>T | upstream_gene_variant | 0.9 | isoniazid | |
| kasA | 2518034 | c.-81T>C | upstream_gene_variant | 0.89 | isoniazid | |
| kasA | 2518040 | c.-75G>T | upstream_gene_variant | 0.88 | isoniazid | |
| kasA | 2518041 | c.-74T>C | upstream_gene_variant | 0.88 | isoniazid | |
| kasA | 2518049 | c.-66G>C | upstream_gene_variant | 0.88 | isoniazid | |
| kasA | 2518053 | c.-62_-60delATTinsCG | upstream_gene_variant | 0.87 | isoniazid | |
| kasA | 2518073 | c.-42T>G | upstream_gene_variant | 0.88 | isoniazid | |
| kasA | 2518085 | c.-30C>T | upstream_gene_variant | 0.8 | isoniazid | |
| kasA | 2518132 | c.18C>T | synonymous_variant | 0.69 | isoniazid | |
| kasA | 2518138 | c.24T>C | synonymous_variant | 0.69 | isoniazid | |
| kasA | 2518146 | p.Phe11Tyr | missense_variant | 0.69 | isoniazid | |
| kasA | 2518152 | p.Ser13Asn | missense_variant | 0.69 | isoniazid | |
| kasA | 2518162 | c.48G>A | synonymous_variant | 0.73 | isoniazid | |
| kasA | 2518169 | p.Val19Leu | missense_variant | 0.73 | isoniazid | |
| kasA | 2518172 | c.58_60delACAinsGG | frameshift_variant&missense_variant | 0.73 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 0.87 | isoniazid | |
| kasA | 2518199 | p.Ile29Val | missense_variant | 0.87 | isoniazid | |
| kasA | 2518219 | c.105T>C | synonymous_variant | 0.83 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 0.83 | isoniazid | |
| kasA | 2518245 | p.His44Arg | missense_variant | 0.93 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 0.93 | isoniazid | |
| kasA | 2518261 | p.Glu49Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518273 | c.159G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518279 | p.Asp55Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518289 | p.Lys59Gln | missense_variant | 1.0 | isoniazid | |
| kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518492 | c.378C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518570 | c.456G>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518573 | c.459G>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 0.94 | isoniazid | |
| kasA | 2518582 | c.468G>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518583 | c.469_471delCAGinsGA | frameshift_variant&missense_variant | 0.94 | isoniazid | |
| kasA | 2518594 | c.480C>T | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518597 | c.483C>G | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518606 | c.492G>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 0.95 | isoniazid | |
| kasA | 2518636 | c.522C>A | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518639 | c.525G>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518657 | c.543G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518663 | c.549T>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518681 | c.567C>T | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518723 | c.609G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518735 | c.621C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518768 | c.654C>G | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518795 | c.681C>A | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518798 | c.684G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518840 | c.726C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518843 | c.729T>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518846 | c.732G>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518855 | c.741C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518879 | c.765A>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518894 | c.780G>A | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518907 | c.793T>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518910 | p.Leu266Met | missense_variant | 0.94 | isoniazid | |
| kasA | 2518915 | c.801T>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518930 | c.816G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518939 | c.825T>C | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518942 | c.828T>C | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2519119 | c.1005G>C | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519134 | c.1020G>A | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519140 | c.1026G>A | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519146 | c.1032C>A | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519152 | c.1038G>C | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519161 | c.1047G>A | synonymous_variant | 0.8 | isoniazid | |
| kasA | 2519215 | c.1101C>T | synonymous_variant | 0.64 | isoniazid | |
| kasA | 2519227 | c.1113G>C | synonymous_variant | 0.64 | isoniazid | |
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783535 | c.508C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783578 | c.465G>A | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783602 | c.441G>A | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783623 | c.420G>A | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783632 | c.411C>G | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783743 | c.300C>G | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783788 | c.255T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783794 | c.249G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783806 | c.237G>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783827 | c.216C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783836 | c.207C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783857 | c.186C>G | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783881 | c.160_162delTTGinsCC | frameshift_variant&missense_variant | 0.97 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783884 | c.159T>G | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>T | synonymous_variant | 0.97 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783968 | c.75G>C | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2752c | 3064989 | c.1203G>C | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064998 | c.1194A>C | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065040 | c.1150_1152delCTCinsTG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065049 | c.1143G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065055 | c.1137T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065070 | c.1122C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065085 | c.1105_1107delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065097 | c.1095C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065130 | c.1062A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 0.97 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065186 | c.1006T>C | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065190 | c.1000_1002delATCinsGG | frameshift_variant&missense_variant | 0.97 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065199 | c.993T>C | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065202 | c.990T>G | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065205 | c.987T>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065210 | c.982T>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065223 | c.969T>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065229 | c.963G>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065232 | c.960T>C | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065235 | c.957G>C | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065241 | c.951A>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065268 | c.924A>G | synonymous_variant | 0.83 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065418 | c.774A>G | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065424 | c.768C>G | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065430 | c.762A>G | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065439 | c.753C>G | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065442 | c.750T>C | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065451 | c.741G>A | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065457 | c.735A>G | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065466 | c.726G>C | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065481 | c.711T>C | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065487 | c.705T>G | synonymous_variant | 0.89 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065490 | c.702A>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065493 | c.699G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065496 | c.696G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065499 | c.693A>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065508 | c.684T>C | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065511 | c.681G>A | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065517 | c.675C>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065532 | c.660A>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065535 | c.657C>T | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065550 | c.642G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065556 | c.636G>T | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065562 | c.630T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065580 | c.612G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065901 | c.291A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065916 | c.276T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065919 | c.273G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065922 | c.270T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065946 | p.Gly82Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065949 | c.243C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065957 | c.235T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065963 | c.229C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065979 | c.213T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065993 | p.Val67Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065994 | c.198T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065997 | c.195C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066006 | c.186G>C | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066017 | c.175C>T | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066024 | c.168T>C | synonymous_variant | 0.91 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066567 | c.-376C>A | upstream_gene_variant | 0.64 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.67 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.67 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 0.73 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066597 | c.-406C>T | upstream_gene_variant | 0.73 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 0.75 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066612 | c.-421G>A | upstream_gene_variant | 0.75 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 0.75 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066618 | c.-427A>G | upstream_gene_variant | 0.73 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066633 | c.-442T>C | upstream_gene_variant | 0.75 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066644 | c.-453T>C | upstream_gene_variant | 0.82 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066647 | c.-456G>A | upstream_gene_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066654 | c.-463G>C | upstream_gene_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066676 | c.-485C>T | upstream_gene_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067379 | c.567C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067400 | c.546C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| thyX | 3067418 | c.528C>G | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| thyX | 3067427 | c.519G>C | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| thyX | 3067430 | c.516C>T | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyX | 3067442 | c.504C>A | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyX | 3067445 | c.501C>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyX | 3067448 | c.498G>A | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyX | 3067454 | c.492C>T | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073887 | p.Ser195Asp | missense_variant | 0.92 | para-aminosalicylic_acid | |
| thyA | 3073892 | c.580T>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| thyA | 3073905 | c.567C>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073944 | c.528C>T | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073968 | c.504C>G | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 0.87 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 0.87 | para-aminosalicylic_acid | |
| thyA | 3074001 | c.471C>G | synonymous_variant | 0.86 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
| thyA | 3074256 | c.216G>A | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
| thyA | 3074267 | p.Ile69Val | missense_variant | 0.69 | para-aminosalicylic_acid | |
| thyA | 3074268 | c.204T>C | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
| thyA | 3074274 | c.198T>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
| thyA | 3074280 | c.192C>T | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074297 | c.175C>T | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074301 | c.171C>T | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074305 | p.Ala56Val | missense_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074307 | c.165A>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074313 | c.159A>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074316 | p.Phe52Leu | missense_variant | 0.84 | para-aminosalicylic_acid | |
| thyA | 3074322 | c.150C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
| thyA | 3074325 | c.147A>G | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
| thyA | 3074334 | c.138T>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
| thyA | 3074337 | c.135C>G | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
| thyA | 3074360 | c.112T>C | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3074361 | c.111T>C | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3074364 | c.108T>C | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3074372 | p.Met34Leu | missense_variant | 0.75 | para-aminosalicylic_acid | |
| thyA | 3074373 | c.99G>A | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
| lpqB | 3623360 | c.1551A>C | synonymous_variant | 0.8 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623363 | c.1548T>C | synonymous_variant | 0.8 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623366 | c.1545T>C | synonymous_variant | 0.82 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623381 | p.Ala510Ile | missense_variant | 0.86 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623388 | p.Thr508Asn | missense_variant | 0.86 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623393 | c.1518A>G | synonymous_variant | 0.87 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623424 | p.Ser496Tyr | missense_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623428 | c.1483T>C | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623429 | c.1482G>C | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623438 | c.1471_1473delTCGinsAC | frameshift_variant&missense_variant | 0.88 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3623442 | p.Ser490Asn | missense_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623444 | c.1467T>C | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623461 | c.1450C>T | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623465 | c.1446G>C | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623468 | c.1443T>C | synonymous_variant | 0.88 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623480 | c.1431C>G | synonymous_variant | 0.86 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623483 | p.Phe476Tyr | missense_variant | 0.77 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623489 | c.1422C>G | synonymous_variant | 0.85 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623492 | c.1419T>G | synonymous_variant | 0.85 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623507 | c.1404C>G | synonymous_variant | 0.85 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623516 | c.1395C>G | synonymous_variant | 0.82 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623522 | c.1389G>C | synonymous_variant | 0.8 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 0.94 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>G | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625699 | c.915C>T | synonymous_variant | 0.96 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625717 | c.-807C>T | upstream_gene_variant | 0.97 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625783 | c.-873C>T | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625801 | c.-891G>C | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 0.96 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625867 | c.747A>G | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625870 | c.-960C>G | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625876 | c.738G>C | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625912 | c.702G>C | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625915 | c.699G>C | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625927 | c.687T>C | synonymous_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626349 | p.Ser89Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626353 | c.261C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626362 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626368 | c.246G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626377 | p.Asp79Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626383 | p.Ala77Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626389 | p.Arg75Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626400 | p.Ile72Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626404 | c.210C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626437 | c.177T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626443 | c.171T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626451 | c.163C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626455 | c.159C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626461 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626777 | c.573C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626825 | c.525T>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626843 | c.-230G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 0.97 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626849 | c.-236C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626924 | c.-311G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626927 | c.-314G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626933 | c.-320C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626996 | c.-383G>A | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627023 | c.-410C>G | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 0.95 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 0.95 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 0.96 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627137 | c.211_213delTTGinsCA | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627143 | c.-530G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627188 | c.162A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627212 | c.-599C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627233 | c.-620T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627239 | c.111C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>C | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627278 | c.-665G>T | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627287 | c.-674C>G | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>G | upstream_gene_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627299 | c.49_51delTTGinsCC | frameshift_variant&missense_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.87 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627359 | c.-746T>G | upstream_gene_variant | 0.81 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 0.8 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627375 | c.-762C>G | upstream_gene_variant | 0.67 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627377 | c.-764G>C | upstream_gene_variant | 0.67 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627380 | c.-767T>C | upstream_gene_variant | 0.67 | bedaquiline | |
| rifampicin | ||||||
| alr | 3840534 | p.Gly296Ala | missense_variant | 0.75 | cycloserine | |
| alr | 3840542 | c.879G>A | synonymous_variant | 0.79 | cycloserine | |
| alr | 3840548 | c.873G>A | synonymous_variant | 0.79 | cycloserine | |
| alr | 3840551 | c.870G>T | synonymous_variant | 0.79 | cycloserine | |
| alr | 3840554 | c.867G>C | synonymous_variant | 0.81 | cycloserine | |
| alr | 3840562 | p.Ile287Val | missense_variant | 0.81 | cycloserine | |
| alr | 3840566 | c.855A>G | synonymous_variant | 0.81 | cycloserine | |
| alr | 3840574 | c.847C>T | synonymous_variant | 0.76 | cycloserine | |
| alr | 3840578 | c.843T>G | synonymous_variant | 0.76 | cycloserine | |
| alr | 3840599 | c.822G>C | synonymous_variant | 0.77 | cycloserine | |
| alr | 3840605 | c.814_816delGTGinsCA | frameshift_variant&missense_variant | 0.77 | cycloserine | |
| alr | 3840620 | c.801T>C | synonymous_variant | 0.82 | cycloserine | |
| alr | 3840624 | p.Leu266Arg | missense_variant | 0.82 | cycloserine | |
| alr | 3840626 | p.Ala265Glu | missense_variant | 0.82 | cycloserine | |
| alr | 3840632 | c.789A>G | synonymous_variant | 0.82 | cycloserine | |
| alr | 3840635 | c.786G>C | synonymous_variant | 0.82 | cycloserine | |
| alr | 3840638 | c.783C>T | synonymous_variant | 0.8 | cycloserine | |
| alr | 3840641 | c.780A>G | synonymous_variant | 0.9 | cycloserine | |
| alr | 3840644 | c.777G>C | synonymous_variant | 0.9 | cycloserine | |
| alr | 3840647 | c.774T>C | synonymous_variant | 0.9 | cycloserine | |
| alr | 3840662 | c.759G>C | synonymous_variant | 0.9 | cycloserine | |
| alr | 3840673 | p.Leu250Met | missense_variant | 0.9 | cycloserine | |
| rpoA | 3877494 | p.Glu338Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877503 | c.1005G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877506 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877587 | c.921A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 0.97 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.97 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877685 | c.823C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877758 | c.750G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877815 | c.693C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877851 | c.657C>T | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3877865 | c.643C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877872 | c.636C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877887 | c.621G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 0.91 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.88 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877968 | c.540C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878043 | c.465G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878046 | c.462T>G | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878097 | c.411G>A | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3878115 | c.393G>A | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878229 | c.279C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 0.97 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoA | 3878295 | c.213A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878376 | c.132G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878384 | c.124C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878418 | c.90C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878454 | c.54A>G | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878458 | p.Asn17Ser | missense_variant | 0.95 | rifampicin | |
| rpoA | 3878471 | p.Val13Leu | missense_variant | 0.94 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.94 | rifampicin | |
| rpoA | 3878484 | c.24C>A | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878490 | c.18C>A | synonymous_variant | 0.92 | rifampicin | |
| rpoA | 3878496 | c.12A>T | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878761 | c.-254G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878776 | c.-269G>C | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878779 | c.-274_-272delATCinsGT | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878788 | c.-281G>T | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878803 | c.-296G>C | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878836 | c.-329G>C | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| rpoA | 3878842 | c.-335G>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878869 | c.-362G>C | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.91 | rifampicin | Uncertain significance |
| rpoA | 3878881 | c.-374C>G | upstream_gene_variant | 0.91 | rifampicin | |
| rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 0.91 | rifampicin | |
| rpoA | 3878894 | c.-387A>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| rpoA | 3878923 | c.-417_-416delGCinsCG | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.96 | rifampicin | Uncertain significance |
| rpoA | 3878953 | c.-446C>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.96 | rifampicin | Uncertain significance |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| rpoA | 3878974 | c.-469_-467delATCinsGG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.93 | rifampicin | Uncertain significance |
| rpoA | 3879001 | c.-494C>T | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879037 | c.-530G>A | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879049 | c.-542A>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879117 | c.-610C>T | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879145 | c.-638G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879148 | c.-641G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3879178 | c.-671T>G | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.89 | rifampicin | |
| rpoA | 3879202 | c.-695T>C | upstream_gene_variant | 0.89 | rifampicin | |
| rpoA | 3879208 | c.-701C>G | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.86 | rifampicin | |
| rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.86 | rifampicin | |
| ddn | 3986630 | c.-214C>G | upstream_gene_variant | 0.82 | delamanid | |
| pretomanid | ||||||
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.82 | delamanid | |
| pretomanid | ||||||
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.81 | delamanid | |
| pretomanid | ||||||
| ddn | 3986665 | c.-179G>C | upstream_gene_variant | 0.79 | delamanid | |
| pretomanid | ||||||
| ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 0.77 | delamanid | |
| pretomanid | ||||||
| ddn | 3986681 | c.-163C>G | upstream_gene_variant | 0.75 | delamanid | |
| pretomanid | ||||||
| ddn | 3986690 | c.-154C>G | upstream_gene_variant | 0.73 | delamanid | |
| pretomanid | ||||||
| ddn | 3986696 | c.-148G>C | upstream_gene_variant | 0.7 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4038329 | p.Glu792Asp | missense_variant | 0.93 | pyrazinamide | |
| clpC1 | 4038338 | c.2367C>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038425 | c.2280C>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038491 | c.2214C>T | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4038502 | p.Ile735Val | missense_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038508 | c.2197C>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038518 | c.2187G>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.91 | pyrazinamide | |
| clpC1 | 4038537 | p.Thr723Ser | missense_variant | 0.91 | pyrazinamide | |
| clpC1 | 4038539 | c.2166G>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4038569 | c.2136C>T | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038575 | c.2130C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038620 | c.2085G>A | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038668 | c.2037G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038677 | c.2028G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038692 | c.2013C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038698 | c.2007C>T | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>T | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038809 | c.1896G>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4038875 | c.1830C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038893 | c.1812C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039025 | c.1680C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>T | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>A | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039119 | c.1585_1586delTCinsAG | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039124 | c.1581C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039223 | c.1482C>T | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039238 | c.1467C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039243 | c.1462C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039259 | c.1446G>A | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039262 | c.1443C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039268 | c.1437C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039319 | c.1384_1386delGCTinsAA | frameshift_variant&missense_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.9 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039484 | c.1221T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039508 | c.1197G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039526 | c.1179G>A | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039532 | c.1173C>T | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039553 | c.1152C>A | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039583 | c.1122C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.86 | pyrazinamide | |
| clpC1 | 4039670 | c.1035G>C | synonymous_variant | 0.87 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.8 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.73 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039739 | c.966C>G | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>A | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.6 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.6 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.6 | pyrazinamide | |
| clpC1 | 4039805 | c.900C>G | synonymous_variant | 0.83 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.8 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.8 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4039943 | c.762G>C | synonymous_variant | 0.82 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>A | synonymous_variant | 0.83 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.82 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.82 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040195 | c.510G>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040200 | c.505T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040204 | c.501G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4040231 | c.474C>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040309 | c.396C>T | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>C | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040419 | c.286C>T | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.94 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040456 | c.249C>T | synonymous_variant | 0.89 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>T | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.89 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.89 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040486 | c.219G>C | synonymous_variant | 0.85 | pyrazinamide | |
| clpC1 | 4040495 | c.210C>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040525 | c.180C>T | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.89 | pyrazinamide | |
| clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040600 | c.103_105delTTAinsCG | frameshift_variant&missense_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.88 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.93 | pyrazinamide | |
| panD | 4044965 | c.-684T>C | upstream_gene_variant | 0.9 | pyrazinamide | |
| panD | 4044977 | c.-696T>C | upstream_gene_variant | 0.91 | pyrazinamide | |
| panD | 4045000 | c.-719A>T | upstream_gene_variant | 0.9 | pyrazinamide | |
| glpK | 4138517 | c.1239A>G | synonymous_variant | 0.9 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138529 | c.1227G>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138550 | c.1206C>T | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138574 | c.1182G>T | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138583 | c.1173G>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138596 | p.Phe387Tyr | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138598 | c.1158G>C | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138640 | c.1116C>T | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138681 | p.Met359Val | missense_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138702 | p.Gln352Glu | missense_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138703 | c.1053C>T | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138706 | c.1050C>G | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138714 | p.Ala348Ser | missense_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138715 | c.1041G>A | synonymous_variant | 0.95 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 0.97 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138751 | c.1005T>C | synonymous_variant | 0.96 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139215 | c.541T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139223 | p.Thr178Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139230 | p.Pro176Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139231 | c.525A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240645 | c.783G>C | synonymous_variant | 0.9 | ethambutol | |
| embC | 4240657 | c.795G>C | synonymous_variant | 0.94 | ethambutol | |
| embC | 4240660 | c.798C>G | synonymous_variant | 0.94 | ethambutol | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240678 | c.816T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240681 | c.819G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240685 | p.Thr275Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240690 | c.828G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240693 | c.831T>C | synonymous_variant | 0.95 | ethambutol | |
| embC | 4240698 | p.Ala279Gly | missense_variant | 0.95 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
| embC | 4240729 | c.867C>G | synonymous_variant | 0.96 | ethambutol | |
| embC | 4240747 | c.885C>T | synonymous_variant | 0.92 | ethambutol | Not assoc w R - Interim |
| embC | 4240759 | c.897C>G | synonymous_variant | 0.92 | ethambutol | |
| embC | 4240765 | c.903C>G | synonymous_variant | 0.92 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 0.91 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 0.9 | ethambutol | |
| embC | 4240795 | c.933C>G | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| embB | 4247452 | c.939C>G | synonymous_variant | 0.92 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247506 | c.993C>G | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247527 | c.1014G>C | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 0.98 | ethambutol | |
| embB | 4247550 | p.Ala346Asp | missense_variant | 0.96 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247629 | c.1116C>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4247632 | c.1119C>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4247638 | c.1125G>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4247645 | p.Glu378Thr | missense_variant | 0.96 | ethambutol | |
| embB | 4247648 | c.1135_1137delGCCinsTG | frameshift_variant&missense_variant | 0.95 | ethambutol | |
| embB | 4247656 | c.1143A>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247657 | p.Pro382Ala | missense_variant | 0.95 | ethambutol | |
| embB | 4247662 | c.1149C>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247677 | c.1164C>G | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| embB | 4247684 | c.1171T>C | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248127 | c.1614G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248133 | c.1620C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248139 | c.1626C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248146 | c.1633_1635delATCinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248149 | p.Thr546Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248161 | c.1648C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248169 | c.1656C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248190 | c.1677G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248211 | c.1698G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol |
