Run ID: ERR4820854
Sample name:
Date: 2024-04-16T12:36:57.099019
Number of reads: 1582476
Percentage reads mapped: 52.97
Median coverage: 33.0
Strain: lineage4.1.2.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.1 | Euro-American | None | 0.97 |
lineage4.1.2 | Euro-American | None | 0.97 |
lineage4.1.2.1 | Euro-American (Haarlem) | RD182 | 0.95 |
lineage4 | Euro-American | None | 0.95 |
lineage6.2.3 | West-Africa 2 | RD702 | 0.06 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
pyrazinamide | panD | p.Val138Ala | Mutation from literature | |
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 0.35 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.37 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
panD | 4043869 | p.Val138Ala | missense_variant | 0.29 | pyrazinamide | Mutation from literature | |
embB | 4247448 | p.His312Arg | missense_variant | 0.23 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 414 | c.414G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 612 | c.612G>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 627 | c.627G>A | synonymous_variant | 0.25 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 720 | c.720G>A | synonymous_variant | 0.38 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.39 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
dnaA | 897 | c.897A>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.45 | isoniazid | Not assoc w R - Interim |
dnaA | 942 | c.942C>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.41 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.39 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.41 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1041 | c.1041G>A | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.43 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1395 | c.1395G>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.23 | isoniazid | |
gyrB | 5806 | c.567C>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5849 | c.610C>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5854 | c.615C>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6304 | c.-998C>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6415 | c.-887G>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6418 | c.-884C>G | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 0.45 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | c.1885_1887delTCGinsAC | frameshift_variant&missense_variant | 0.32 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7228 | c.-74C>T | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7234 | c.1995C>T | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7246 | c.2007T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7406 | c.105G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>A | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7562 | c.261C>T | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382_384delAGGinsCC | frameshift_variant&missense_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>A | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7814 | c.513C>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7823 | c.522G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7853 | c.552C>G | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>A | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>A | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8276 | c.975G>A | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8337 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8367 | c.1066C>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.6 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.38 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8807 | c.1506C>T | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8816 | c.1515C>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.5 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.65 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.3 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>A | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.41 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9218 | c.1917C>T | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9293 | c.1992G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | c.2007C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9312 | c.2011C>T | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9317 | c.2016G>T | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9365 | c.2064G>A | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9413 | c.2112G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.29 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.3 | isoniazid | |
fgd1 | 490782 | c.-1G>C | upstream_gene_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.31 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.35 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491001 | c.219G>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 0.3 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.32 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491535 | c.753G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491553 | c.771G>A | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491591 | p.Lys270Met | missense_variant | 0.62 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>A | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491649 | c.867C>T | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491661 | c.879C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575649 | p.Val101Ala | missense_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 575662 | c.315C>G | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>A | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 575674 | c.327G>C | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
mshA | 575679 | p.Asn111Ser | missense_variant | 0.73 | ethionamide | Not assoc w R |
isoniazid | Not assoc w R | |||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.2 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575701 | c.354G>A | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.23 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.31 | ethionamide | |
isoniazid | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.31 | ethionamide | |
isoniazid | ||||||
mshA | 575809 | c.462C>T | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.37 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575833 | c.486C>G | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 0.32 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.31 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.31 | ethionamide | |
isoniazid | ||||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575920 | c.573C>G | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575924 | p.Gly193Ser | missense_variant | 0.25 | ethionamide | |
isoniazid | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.28 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620268 | c.378G>C | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620286 | c.396G>C | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.31 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.27 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>A | synonymous_variant | 0.26 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620688 | c.798G>C | synonymous_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | c.820_822delGTGinsAA | frameshift_variant&missense_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656052 | c.1419A>C | synonymous_variant | 0.29 | ethionamide | |
Rv0565c | 656073 | c.1396_1398delTTGinsCC | frameshift_variant&missense_variant | 0.29 | ethionamide | Uncertain significance |
Rv0565c | 656076 | c.1395C>T | synonymous_variant | 0.25 | ethionamide | |
Rv0565c | 656085 | c.1386A>G | synonymous_variant | 0.26 | ethionamide | |
Rv0565c | 656088 | c.1383A>G | synonymous_variant | 0.26 | ethionamide | |
Rv0565c | 656091 | c.1380T>C | synonymous_variant | 0.26 | ethionamide | |
Rv0565c | 656112 | c.1359C>G | synonymous_variant | 0.23 | ethionamide | |
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 0.32 | ethionamide | |
Rv0565c | 656277 | c.1194C>G | synonymous_variant | 0.29 | ethionamide | |
Rv0565c | 656289 | c.1182C>G | synonymous_variant | 0.24 | ethionamide | |
Rv0565c | 656298 | c.1173G>C | synonymous_variant | 0.25 | ethionamide | |
Rv0565c | 656412 | c.1059T>G | synonymous_variant | 0.31 | ethionamide | |
Rv0565c | 656418 | c.1053A>G | synonymous_variant | 0.31 | ethionamide | |
Rv0565c | 656448 | c.1021_1023delATTinsGC | frameshift_variant&missense_variant | 0.34 | ethionamide | Uncertain significance |
Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.41 | ethionamide | |
Rv0565c | 656457 | c.1014T>C | synonymous_variant | 0.43 | ethionamide | |
Rv0565c | 656469 | c.1002T>C | synonymous_variant | 0.41 | ethionamide | |
Rv0565c | 656475 | c.996A>G | synonymous_variant | 0.43 | ethionamide | |
Rv0565c | 656484 | c.987T>C | synonymous_variant | 0.41 | ethionamide | |
Rv0565c | 656487 | c.984T>C | synonymous_variant | 0.36 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656493 | c.978C>G | synonymous_variant | 0.39 | ethionamide | |
Rv0565c | 656502 | c.969C>T | synonymous_variant | 0.38 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 0.38 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.26 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.26 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.29 | ethionamide | |
Rv0565c | 657267 | c.202_204delTCGinsCC | frameshift_variant&synonymous_variant | 0.26 | ethionamide | Uncertain significance |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.41 | ethionamide | |
Rv0565c | 657303 | c.168C>T | synonymous_variant | 0.44 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.38 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 657327 | c.144C>G | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.25 | ethionamide | |
Rv0565c | 657356 | p.Ile39Val | missense_variant | 0.29 | ethionamide | |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 0.29 | ethionamide | |
Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 0.35 | ethionamide | |
Rv0565c | 657600 | c.-132_-131delCA | upstream_gene_variant | 0.38 | ethionamide | |
Rv0565c | 657606 | c.-136T>G | upstream_gene_variant | 0.45 | ethionamide | |
Rv0565c | 657607 | c.-138_-137insCA | upstream_gene_variant | 0.4 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.54 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.52 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.5 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.48 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.5 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.38 | ethionamide | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.29 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.32 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.32 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.26 | isoniazid | |
hadA | 732253 | c.324T>C | synonymous_variant | 0.23 | isoniazid | |
hadA | 732259 | c.330T>C | synonymous_variant | 0.24 | isoniazid | |
hadA | 732268 | c.339T>G | synonymous_variant | 0.25 | isoniazid | |
hadA | 732270 | p.Glu114Val | missense_variant | 0.25 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 0.25 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.33 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.32 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.34 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.41 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.39 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.38 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.47 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.44 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.43 | isoniazid | |
nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
nusG | 734093 | c.-161A>C | upstream_gene_variant | 0.27 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 0.28 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.25 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.25 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.24 | rifampicin | Uncertain significance |
nusG | 734123 | c.-131C>G | upstream_gene_variant | 0.21 | rifampicin | |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.21 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.23 | rifampicin | |
nusG | 734135 | c.-119G>C | upstream_gene_variant | 0.23 | rifampicin | |
nusG | 734144 | c.-110G>C | upstream_gene_variant | 0.2 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.21 | rifampicin | |
nusG | 734364 | c.111G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734370 | c.117A>G | synonymous_variant | 0.23 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.27 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.34 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.35 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.39 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.49 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.5 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.47 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.41 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.41 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.41 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.44 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.41 | rifampicin | |
nusG | 734601 | c.348C>G | synonymous_variant | 0.43 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.48 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760115 | c.309C>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.54 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.55 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.55 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.65 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.45 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.44 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.49 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.47 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.37 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.53 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.51 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.49 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.42 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.37 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.57 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 761720 | c.1914_1916delCGAinsGG | frameshift_variant&synonymous_variant | 0.47 | rifampicin | |
rpoB | 761727 | p.Ser641Gly | missense_variant | 0.45 | rifampicin | |
rpoB | 761728 | c.1923dupC | frameshift_variant | 0.45 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.35 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.36 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.21 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.25 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761849 | p.Cys681Trp | missense_variant | 0.2 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.53 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.55 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.51 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.6 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.45 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.45 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.46 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.48 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.4 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.44 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.42 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.31 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.46 | rifampicin | |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.43 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.24 | rifampicin | Uncertain significance |
rpoB | 762788 | c.2982G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.38 | rifampicin | Uncertain significance |
rpoB | 762810 | c.3004_3006delGCCinsTG | frameshift_variant&missense_variant | 0.4 | rifampicin | |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.4 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762926 | c.3120C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.52 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.53 | rifampicin | |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.57 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.61 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.53 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.31 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.27 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.27 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.51 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.54 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.39 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.2 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763963 | c.594C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 0.44 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.45 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.47 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.45 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.48 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.41 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.61 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.56 | rifampicin | |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.59 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.49 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765150 | p.Gly594Glu | missense_variant | 0.9 | rifampicin | Not assoc w R |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.37 | rifampicin | Uncertain significance |
rpoC | 765329 | p.Ser654Gly | missense_variant | 0.39 | rifampicin | |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.35 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.34 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.54 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.55 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.53 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.38 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.44 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.47 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.38 | rifampicin | |
rpoC | 766549 | c.3180G>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.34 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.44 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766660 | c.3291G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.44 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 766882 | c.3513C>T | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.4 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.46 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.52 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.47 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.22 | rifampicin | |
rpoC | 767275 | c.3906T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 0.22 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777116 | c.1365C>T | synonymous_variant | 0.25 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777133 | p.Val450Ile | missense_variant | 0.29 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 0.35 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.37 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.38 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.39 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.27 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781605 | p.Ile16Val | missense_variant | 0.37 | streptomycin | Uncertain significance |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.38 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.47 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.45 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.46 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.5 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.5 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.51 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.52 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.53 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.53 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.46 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.46 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.44 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.5 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.56 | streptomycin | Uncertain significance |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.43 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.44 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.49 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.44 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.43 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.41 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.33 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.35 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801127 | p.Ala107Thr | missense_variant | 0.2 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 0.32 | linezolid | |
rplC | 801147 | c.339T>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801150 | c.342G>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.36 | linezolid | |
rplC | 801156 | c.348T>A | synonymous_variant | 0.34 | linezolid | |
rplC | 801168 | c.360C>G | synonymous_variant | 0.42 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.42 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.44 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.51 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.58 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.29 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.25 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.22 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.21 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.24 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.23 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.3 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.25 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.27 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.39 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.31 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.3 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.31 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.31 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.31 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.36 | linezolid | |
fbiC | 1303501 | c.571C>T | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303681 | c.751T>C | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.3 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303998 | c.1068T>G | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304161 | p.Arg411Ser | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304174 | p.Val415Ala | missense_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304184 | c.1254G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304187 | c.1257T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304208 | c.1278C>T | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304739 | c.1809C>T | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.6 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304862 | c.1932G>A | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305372 | c.2442G>A | synonymous_variant | 0.22 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305384 | c.2454G>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.2 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305417 | c.2487C>G | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1365042 | c.630G>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1365057 | c.645C>T | synonymous_variant | 0.18 | pyrazinamide | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.29 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.33 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.8 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.75 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.67 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.67 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.58 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.59 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.62 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.56 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476707 | n.3050C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
inhA | 1673523 | c.-679G>T | upstream_gene_variant | 0.22 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673657 | p.Thr73Lys | missense_variant | 0.27 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673660 | p.Ala74Glu | missense_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.26 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1673685 | c.-517C>T | upstream_gene_variant | 0.28 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673710 | p.Leu91Ile | missense_variant | 0.33 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673716 | p.Ala93Lys | missense_variant | 0.28 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673733 | p.Met98Ile | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673750 | p.Lys104Arg | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1673901 | c.-301A>G | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673905 | p.Ser156Ala | missense_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1673916 | c.-286A>C | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673917 | p.Val160Leu | missense_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 0.33 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673941 | p.Ala168Ser | missense_variant | 0.35 | ethionamide | |
isoniazid | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.46 | ethionamide | |
isoniazid | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.39 | ethionamide | |
isoniazid | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.39 | ethionamide | |
isoniazid | ||||||
fabG1 | 1674079 | p.Pro214Ala | missense_variant | 0.48 | ethionamide | |
isoniazid | ||||||
inhA | 1674504 | c.303C>G | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.41 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.39 | ethionamide | |
isoniazid | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.45 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.5 | ethionamide | |
isoniazid | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.33 | ethionamide | |
isoniazid | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
inhA | 1674888 | c.687C>G | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.43 | ethionamide | |
isoniazid | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.37 | ethionamide | |
isoniazid | ||||||
inhA | 1674954 | c.753G>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674960 | c.759C>G | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
inhA | 1674966 | c.765T>G | synonymous_variant | 0.31 | ethionamide | |
isoniazid | ||||||
inhA | 1674967 | p.Asp256Thr | missense_variant | 0.31 | ethionamide | |
isoniazid | ||||||
rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.21 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.27 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834081 | c.540C>T | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.4 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.46 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.55 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.53 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.51 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.25 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.32 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.33 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.35 | linezolid | |
tsnR | 1853423 | c.-183C>T | upstream_gene_variant | 0.34 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.34 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.36 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.27 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1917975 | c.36C>G | synonymous_variant | 0.27 | capreomycin | |
tlyA | 1917981 | c.42G>C | synonymous_variant | 0.28 | capreomycin | |
tlyA | 1917990 | c.51G>C | synonymous_variant | 0.27 | capreomycin | |
tlyA | 1917993 | c.54A>G | synonymous_variant | 0.28 | capreomycin | Not assoc w R - Interim |
tlyA | 1917996 | c.57A>G | synonymous_variant | 0.28 | capreomycin | |
tlyA | 1918002 | c.63A>G | synonymous_variant | 0.27 | capreomycin | |
tlyA | 1918036 | p.Arg33Ser | missense_variant | 0.17 | capreomycin | |
bacA | 2064903 | c.-175G>A | upstream_gene_variant | 0.27 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064912 | c.-184A>G | upstream_gene_variant | 0.32 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064915 | c.-187G>C | upstream_gene_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064933 | c.-205A>G | upstream_gene_variant | 0.4 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064936 | c.-208C>G | upstream_gene_variant | 0.39 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064942 | c.-214G>A | upstream_gene_variant | 0.39 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.4 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.43 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.4 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.43 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.36 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.43 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
ndh | 2101756 | c.1287G>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101765 | c.1278C>G | synonymous_variant | 0.26 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101768 | c.1275C>A | synonymous_variant | 0.25 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101771 | c.1272T>G | synonymous_variant | 0.26 | ethionamide | |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2101774 | c.1269T>C | synonymous_variant | 0.26 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101777 | c.1266C>G | synonymous_variant | 0.25 | ethionamide | Not assoc w R - Interim |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2101783 | c.1260T>G | synonymous_variant | 0.27 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101804 | c.1239T>G | synonymous_variant | 0.29 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101808 | p.Thr412Ser | missense_variant | 0.26 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101830 | p.Ile405Val | missense_variant | 0.28 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101837 | p.Ala402Val | missense_variant | 0.23 | ethionamide | Uncertain significance |
delamanid | ||||||
isoniazid | Uncertain significance | |||||
ndh | 2101888 | c.1155T>C | synonymous_variant | 0.21 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101894 | c.1149T>G | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 0.28 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 0.31 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.36 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101939 | c.1104A>G | synonymous_variant | 0.42 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 0.47 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101963 | c.1080G>A | synonymous_variant | 0.48 | ethionamide | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2101966 | c.1077T>G | synonymous_variant | 0.47 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 0.43 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101988 | p.Ala352Asp | missense_variant | 0.38 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101990 | c.1053G>C | synonymous_variant | 0.37 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101993 | c.1050A>G | synonymous_variant | 0.38 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102014 | c.1029C>G | synonymous_variant | 0.35 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102020 | c.1023A>G | synonymous_variant | 0.27 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102023 | c.1020G>C | synonymous_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102026 | c.1017G>C | synonymous_variant | 0.2 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102218 | c.825C>A | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102227 | c.816C>T | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102230 | c.813G>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102233 | c.810G>A | synonymous_variant | 0.26 | ethionamide | Not assoc w R - Interim |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102302 | c.741G>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102305 | c.738T>G | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
pncA | 2289930 | c.-689A>G | upstream_gene_variant | 0.38 | pyrazinamide | |
pncA | 2289943 | c.-702T>G | upstream_gene_variant | 0.33 | pyrazinamide | |
pncA | 2289948 | c.-707C>T | upstream_gene_variant | 0.35 | pyrazinamide | |
pncA | 2289949 | c.-708A>G | upstream_gene_variant | 0.33 | pyrazinamide | |
pncA | 2289987 | c.-746C>T | upstream_gene_variant | 0.24 | pyrazinamide | |
pncA | 2289988 | c.-747G>C | upstream_gene_variant | 0.23 | pyrazinamide | |
pncA | 2289991 | c.-750G>C | upstream_gene_variant | 0.27 | pyrazinamide | |
pncA | 2289994 | c.-753A>G | upstream_gene_variant | 0.23 | pyrazinamide | |
pncA | 2289997 | c.-756G>C | upstream_gene_variant | 0.23 | pyrazinamide | |
pncA | 2290000 | c.-759C>T | upstream_gene_variant | 0.22 | pyrazinamide | |
pncA | 2290009 | c.-768A>C | upstream_gene_variant | 0.43 | pyrazinamide | |
pncA | 2290015 | c.-774A>C | upstream_gene_variant | 0.5 | pyrazinamide | |
pncA | 2290024 | c.-783C>G | upstream_gene_variant | 0.47 | pyrazinamide | |
pncA | 2290030 | c.-791_-789delAATinsCC | upstream_gene_variant | 0.47 | pyrazinamide | |
pncA | 2290033 | c.-792C>G | upstream_gene_variant | 0.47 | pyrazinamide | |
pncA | 2290038 | c.-797G>A | upstream_gene_variant | 0.43 | pyrazinamide | |
pncA | 2290042 | c.-801T>C | upstream_gene_variant | 0.46 | pyrazinamide | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.61 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.51 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.47 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.26 | isoniazid | |
kasA | 2518076 | c.-39C>T | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2518132 | c.18C>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518138 | c.24T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518146 | p.Phe11Tyr | missense_variant | 0.34 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 0.49 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.51 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 0.51 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 0.46 | isoniazid | |
kasA | 2518234 | c.120G>A | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518447 | c.333T>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518459 | c.345T>C | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518462 | c.348A>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518468 | c.354A>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518474 | c.360G>A | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518483 | c.369C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.23 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.24 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.25 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.15 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.27 | isoniazid | |
kasA | 2518921 | c.807T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518927 | c.813C>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518936 | c.822C>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518939 | c.825T>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518951 | c.837G>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518954 | c.840C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518963 | c.849T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518969 | c.855T>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518975 | c.861C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518979 | c.865A>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.35 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.37 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.37 | isoniazid | |
kasA | 2519108 | c.994_996delGATinsCG | frameshift_variant&missense_variant | 0.37 | isoniazid | |
kasA | 2519116 | c.1002C>G | synonymous_variant | 0.38 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.43 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.41 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.34 | isoniazid | |
ahpC | 2726258 | c.66C>T | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
ahpC | 2726303 | c.111T>C | synonymous_variant | 0.35 | isoniazid | |
ahpC | 2726311 | p.Ser40Asn | missense_variant | 0.26 | isoniazid | |
ahpC | 2726315 | p.Asp41Glu | missense_variant | 0.25 | isoniazid | |
ahpC | 2726318 | p.Glu42Asp | missense_variant | 0.26 | isoniazid | |
ahpC | 2726322 | c.130_132delCCAinsGC | frameshift_variant&missense_variant | 0.26 | isoniazid | Uncertain significance |
ahpC | 2726330 | c.138G>A | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
ahpC | 2726336 | c.144G>C | synonymous_variant | 0.28 | isoniazid | |
ahpC | 2726348 | c.156T>C | synonymous_variant | 0.26 | isoniazid | |
ahpC | 2726357 | c.165A>G | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
ahpC | 2726579 | c.387T>C | synonymous_variant | 0.24 | isoniazid | |
ahpC | 2726591 | c.399C>G | synonymous_variant | 0.23 | isoniazid | |
ahpC | 2726593 | p.Val134Ala | missense_variant | 0.23 | isoniazid | |
ahpC | 2726600 | c.408T>C | synonymous_variant | 0.27 | isoniazid | |
ahpC | 2726601 | p.Ile137Leu | missense_variant | 0.27 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.42 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.44 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.31 | isoniazid | |
ahpC | 2726672 | c.480G>A | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
ahpC | 2726675 | c.483A>G | synonymous_variant | 0.32 | isoniazid | |
ahpC | 2726681 | c.489A>C | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
ahpC | 2726693 | c.501C>G | synonymous_variant | 0.31 | isoniazid | |
ahpC | 2726696 | c.504C>G | synonymous_variant | 0.29 | isoniazid | |
folC | 2746375 | c.1224G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
folC | 2747745 | c.-147A>C | upstream_gene_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2747751 | c.-154_-153delGCinsCG | upstream_gene_variant | 0.34 | para-aminosalicylic_acid | |
folC | 2747759 | c.-161T>C | upstream_gene_variant | 0.32 | para-aminosalicylic_acid | |
folC | 2747760 | c.-162G>T | upstream_gene_variant | 0.32 | para-aminosalicylic_acid | |
folC | 2747772 | c.-174C>G | upstream_gene_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2747790 | c.-192G>C | upstream_gene_variant | 0.32 | para-aminosalicylic_acid | |
Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.35 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.56 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.56 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.56 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.61 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.54 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.51 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.57 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.51 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.53 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.65 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.56 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783146 | c.897G>A | synonymous_variant | 0.58 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.57 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.62 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783179 | c.864G>C | synonymous_variant | 0.58 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.56 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783209 | c.834G>A | synonymous_variant | 0.58 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783329 | c.714G>A | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783344 | c.699C>G | synonymous_variant | 0.46 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783497 | c.544_546delTTGinsCC | frameshift_variant&missense_variant | 0.24 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.25 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783521 | c.522G>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.46 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.51 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.54 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.53 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.51 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784411 | c.-369G>C | upstream_gene_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784452 | c.-410C>T | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784454 | c.-412G>A | upstream_gene_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784456 | c.-414A>C | upstream_gene_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784472 | c.-430C>A | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
ribD | 2987046 | p.Val70Ile | missense_variant | 0.2 | para-aminosalicylic_acid | |
Rv2680 | 2996034 | c.-71G>A | upstream_gene_variant | 0.24 | capreomycin | Uncertain significance |
Rv2752c | 3064838 | c.1354T>C | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064860 | c.1332G>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064872 | c.1320T>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064877 | p.Ser439Ala | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064881 | p.Ser437Ala | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064887 | c.1305A>G | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064893 | c.1299C>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064896 | c.1296T>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065183 | p.Ser337Ala | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065186 | c.1006T>C | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065196 | c.996T>C | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065202 | c.990T>G | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065205 | c.987T>C | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065223 | c.969T>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065412 | c.780G>A | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065418 | c.774A>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065421 | c.771G>A | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065442 | c.750T>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065451 | c.741G>A | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065457 | c.735A>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065946 | p.Gly82Ala | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065955 | c.235_237delTTGinsCC | frameshift_variant&missense_variant | 0.29 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.32 | ethambutol | Uncertain significance |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065994 | c.198T>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066009 | c.183G>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066024 | c.168T>G | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066054 | c.138T>G | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066066 | c.126T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066074 | c.118C>T | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066078 | c.114C>T | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066102 | c.90C>T | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066309 | c.-118T>C | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066315 | c.-124C>T | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066330 | c.-139G>C | upstream_gene_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066335 | c.-144T>C | upstream_gene_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066339 | c.-148G>C | upstream_gene_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066360 | c.-169T>C | upstream_gene_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066369 | c.-180_-178delAGCinsGCG | upstream_gene_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066380 | c.-189A>G | upstream_gene_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066396 | c.-207_-205delGCGinsAC | upstream_gene_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066399 | c.-210_-208delATTinsTCC | upstream_gene_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066561 | c.-370A>C | upstream_gene_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066810 | c.-619G>A | upstream_gene_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067274 | c.672C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067277 | c.669C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067281 | p.Val222Ala | missense_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067284 | p.Ala221Gly | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067286 | c.660C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067289 | c.657C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067292 | c.654G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067295 | c.651C>T | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067316 | c.630A>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067325 | c.621A>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.49 | para-aminosalicylic_acid | |
thyX | 3067376 | c.570G>A | synonymous_variant | 0.48 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.57 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.52 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.55 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.34 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067559 | c.387C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067577 | c.369G>A | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067583 | c.363C>G | synonymous_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067601 | p.Arg115His | missense_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 0.41 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyX | 3067631 | c.315C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.49 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>C | synonymous_variant | 0.52 | para-aminosalicylic_acid | |
thyX | 3067691 | c.253_255delATCinsCG | frameshift_variant&missense_variant | 0.49 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067736 | c.208_210delTTCinsCT | frameshift_variant&missense_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067772 | c.174C>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>A | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.55 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.55 | para-aminosalicylic_acid | |
thyX | 3067883 | c.63C>G | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>C | synonymous_variant | 0.49 | para-aminosalicylic_acid | |
thyX | 3067889 | c.57C>G | synonymous_variant | 0.48 | para-aminosalicylic_acid | |
thyX | 3067898 | p.Asp16Glu | missense_variant | 0.48 | para-aminosalicylic_acid | |
thyX | 3067935 | p.Thr4Ile | missense_variant | 0.43 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3073917 | c.555C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyA | 3073920 | c.552C>G | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3073956 | c.516G>C | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074127 | c.345G>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074130 | c.342G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyA | 3074175 | c.297A>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3074181 | c.291A>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3074187 | c.285T>C | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3087272 | c.453A>C | synonymous_variant | 0.18 | cycloserine | |
ald | 3087278 | p.Gln153His | missense_variant | 0.22 | cycloserine | |
ald | 3087281 | c.462G>C | synonymous_variant | 0.21 | cycloserine | |
ald | 3087284 | c.465C>G | synonymous_variant | 0.23 | cycloserine | |
ald | 3087290 | c.471T>C | synonymous_variant | 0.27 | cycloserine | |
ald | 3087305 | c.486G>C | synonymous_variant | 0.42 | cycloserine | |
ald | 3087311 | c.492C>G | synonymous_variant | 0.41 | cycloserine | |
ald | 3087318 | c.499_501delGAAinsAG | frameshift_variant&missense_variant | 0.38 | cycloserine | |
ald | 3087344 | c.525C>G | synonymous_variant | 0.39 | cycloserine | |
ald | 3087347 | c.528C>G | synonymous_variant | 0.38 | cycloserine | |
ald | 3087356 | c.537C>G | synonymous_variant | 0.42 | cycloserine | |
ald | 3087368 | c.549A>G | synonymous_variant | 0.3 | cycloserine | |
ald | 3087375 | p.Ile186Val | missense_variant | 0.27 | cycloserine | |
ald | 3087380 | c.561C>G | synonymous_variant | 0.27 | cycloserine | |
whiB7 | 3569166 | c.-487C>G | upstream_gene_variant | 0.21 | streptomycin | |
amikacin | ||||||
kanamycin | ||||||
whiB7 | 3569169 | c.-490T>C | upstream_gene_variant | 0.19 | streptomycin | |
amikacin | ||||||
kanamycin | ||||||
lpqB | 3624037 | c.874A>C | synonymous_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624041 | p.Glu290Asp | missense_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624050 | c.861C>G | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624077 | c.834G>A | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624082 | c.829A>C | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624086 | c.825C>T | synonymous_variant | 0.26 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624092 | c.817_819delAGGinsCC | frameshift_variant&missense_variant | 0.26 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3624100 | c.811T>C | synonymous_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624101 | c.810C>G | synonymous_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624107 | c.804C>T | synonymous_variant | 0.2 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624143 | c.768T>C | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624166 | p.Met249Leu | missense_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624167 | c.744C>T | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624173 | c.738A>C | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624179 | c.732C>G | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624185 | c.726C>T | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624194 | c.717C>G | synonymous_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624200 | c.711A>G | synonymous_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624204 | p.Ser236Asn | missense_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624209 | c.702A>C | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624649 | c.262T>C | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624673 | p.Ala80Ser | missense_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624674 | c.237C>T | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624680 | c.231T>A | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624686 | c.223_225delGAAinsCG | frameshift_variant&missense_variant | 0.27 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3624701 | c.210T>C | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624704 | c.207G>C | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624707 | c.204G>C | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.37 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.26 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625165 | c.-255G>C | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625206 | p.Ser470Ala | missense_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.4 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.44 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625301 | p.Ala438Gly | missense_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625549 | c.-639G>A | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.42 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.49 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.45 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.38 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.3 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.29 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.31 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.45 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.52 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.49 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.56 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.54 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.57 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.52 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.37 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625876 | c.738G>C | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626157 | p.Ala153Ser | missense_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626158 | c.456C>T | synonymous_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626161 | c.453C>A | synonymous_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626170 | c.444T>C | synonymous_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626687 | c.-74G>T | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.23 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.31 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.21 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.21 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.21 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.32 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.42 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.29 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.35 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.4 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.34 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.37 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.45 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.48 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.48 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.34 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627872 | c.-523T>C | upstream_gene_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627893 | c.-544T>G | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627917 | c.-568G>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627920 | c.-571A>G | upstream_gene_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
fbiB | 3642560 | c.1026T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642566 | c.1032A>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642581 | c.1047A>C | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642593 | c.1059G>T | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642609 | p.Ser359Cys | missense_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642614 | c.1080C>T | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
rpoA | 3877494 | p.Glu338Asp | missense_variant | 0.42 | rifampicin | Uncertain significance |
rpoA | 3877503 | c.1005G>C | synonymous_variant | 0.43 | rifampicin | |
rpoA | 3877507 | p.Gly334Ala | missense_variant | 0.45 | rifampicin | |
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.46 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.58 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.59 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.53 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.52 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.46 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.46 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.55 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.62 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.62 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.58 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.6 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.62 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.61 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.59 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoA | 3877923 | c.585C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.55 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.56 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoA | 3878043 | c.465G>A | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3878058 | c.450G>T | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878082 | c.426T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.29 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoA | 3878172 | c.336G>C | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878181 | c.327C>T | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.51 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.44 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.41 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.31 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878340 | c.168C>T | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.44 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.43 | rifampicin | |
rpoA | 3878478 | c.30C>G | synonymous_variant | 0.41 | rifampicin | |
rpoA | 3878683 | c.-176G>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 0.5 | rifampicin | Uncertain significance |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.54 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.57 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.57 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.63 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.63 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.63 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.66 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.63 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.61 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.62 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.66 | rifampicin | |
rpoA | 3878860 | c.-353C>T | upstream_gene_variant | 0.67 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.59 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.59 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.62 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 0.62 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.61 | rifampicin | Uncertain significance |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.52 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.53 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.53 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.55 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.56 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.51 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.51 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.51 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.49 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.59 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.58 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.53 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.47 | rifampicin | |
rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.21 | rifampicin | |
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.33 | delamanid | |
pretomanid | ||||||
ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.28 | delamanid | |
pretomanid | ||||||
clpC1 | 4038212 | c.2493T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038239 | c.2466T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038255 | p.Val817Lys | missense_variant | 0.32 | pyrazinamide | |
clpC1 | 4038271 | p.Pro812Ala | missense_variant | 0.32 | pyrazinamide | |
clpC1 | 4038272 | c.2431_2433delGGTinsAC | frameshift_variant&missense_variant | 0.31 | pyrazinamide | |
clpC1 | 4038275 | c.2430A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038278 | c.2427T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038308 | c.2395_2397delGTGinsAT | frameshift_variant&missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.27 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.29 | pyrazinamide | |
clpC1 | 4038460 | p.Leu749Met | missense_variant | 0.33 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.29 | pyrazinamide | |
clpC1 | 4038489 | p.Ala739Gly | missense_variant | 0.29 | pyrazinamide | |
clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038497 | p.Ser736Gln | missense_variant | 0.28 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.47 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.37 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.39 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038821 | c.1884G>A | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.57 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.51 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039229 | c.1476C>G | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.23 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.4 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039480 | c.1225C>A | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>G | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.47 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.48 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039625 | c.1080G>A | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.66 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040444 | c.261C>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040501 | c.204C>T | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040657 | c.48T>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
panD | 4043865 | c.415_417delGGAinsCG | frameshift_variant&missense_variant | 0.29 | pyrazinamide | Uncertain significance |
panD | 4043872 | p.Gly137Val | missense_variant | 0.3 | pyrazinamide | Uncertain significance |
panD | 4043876 | p.Leu136Ile | missense_variant | 0.33 | pyrazinamide | |
panD | 4043883 | c.399C>T | synonymous_variant | 0.33 | pyrazinamide | |
panD | 4043886 | c.396A>G | synonymous_variant | 0.33 | pyrazinamide | |
panD | 4043896 | p.Gly129Ala | missense_variant | 0.31 | pyrazinamide | |
panD | 4043903 | p.Asn127Asp | missense_variant | 0.3 | pyrazinamide | |
panD | 4043913 | c.369T>C | synonymous_variant | 0.28 | pyrazinamide | |
panD | 4043916 | c.366A>G | synonymous_variant | 0.3 | pyrazinamide | |
panD | 4044105 | c.177G>C | synonymous_variant | 0.38 | pyrazinamide | |
panD | 4044117 | c.165G>C | synonymous_variant | 0.35 | pyrazinamide | |
panD | 4044120 | c.162A>C | synonymous_variant | 0.33 | pyrazinamide | |
panD | 4044712 | c.-431C>A | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044725 | c.-444C>T | upstream_gene_variant | 0.27 | pyrazinamide | |
panD | 4044737 | c.-456T>C | upstream_gene_variant | 0.29 | pyrazinamide | |
panD | 4044746 | c.-467_-465delGTGinsAC | upstream_gene_variant | 0.33 | pyrazinamide | |
panD | 4044752 | c.-471T>C | upstream_gene_variant | 0.38 | pyrazinamide | |
panD | 4044758 | c.-477C>T | upstream_gene_variant | 0.4 | pyrazinamide | |
panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 0.39 | pyrazinamide | |
panD | 4044788 | c.-507G>C | upstream_gene_variant | 0.44 | pyrazinamide | |
panD | 4044791 | c.-510G>C | upstream_gene_variant | 0.48 | pyrazinamide | |
panD | 4044800 | c.-519C>G | upstream_gene_variant | 0.52 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.44 | pyrazinamide | |
panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 0.42 | pyrazinamide | |
panD | 4044823 | c.-542G>C | upstream_gene_variant | 0.42 | pyrazinamide | |
panD | 4044844 | c.-563T>C | upstream_gene_variant | 0.4 | pyrazinamide | |
panD | 4044848 | c.-567T>G | upstream_gene_variant | 0.4 | pyrazinamide | |
panD | 4044854 | c.-573A>G | upstream_gene_variant | 0.31 | pyrazinamide | |
panD | 4044860 | c.-579C>G | upstream_gene_variant | 0.31 | pyrazinamide | |
panD | 4044872 | c.-591C>G | upstream_gene_variant | 0.26 | pyrazinamide | |
panD | 4044986 | c.-705C>G | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044989 | c.-708T>C | upstream_gene_variant | 0.24 | pyrazinamide | |
panD | 4045000 | c.-719A>C | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4045001 | c.-720G>C | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4045019 | c.-738G>C | upstream_gene_variant | 0.27 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.28 | pyrazinamide | |
panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.3 | pyrazinamide | |
panD | 4045034 | c.-753A>C | upstream_gene_variant | 0.33 | pyrazinamide | |
panD | 4045055 | c.-774T>G | upstream_gene_variant | 0.31 | pyrazinamide | |
panD | 4045067 | c.-786C>G | upstream_gene_variant | 0.26 | pyrazinamide | |
panD | 4045070 | c.-789C>T | upstream_gene_variant | 0.24 | pyrazinamide | |
panD | 4045076 | c.-795A>C | upstream_gene_variant | 0.24 | pyrazinamide | |
panD | 4045088 | c.-807T>C | upstream_gene_variant | 0.19 | pyrazinamide | |
glpK | 4138622 | c.1134C>G | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138625 | c.1131G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138646 | c.1110G>C | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.39 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 0.41 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138763 | c.993G>A | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138774 | p.Ser328Ala | missense_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138778 | c.978C>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.38 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4139588 | c.168G>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139601 | p.Arg52Gln | missense_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139611 | p.Ile49Val | missense_variant | 0.59 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139615 | c.141G>A | synonymous_variant | 0.59 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4139651 | c.103_105delCACinsGG | frameshift_variant&missense_variant | 0.56 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4139684 | c.72C>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139687 | c.69C>G | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
embC | 4239298 | c.-565C>T | upstream_gene_variant | 0.97 | ethambutol | Not assoc w R |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.18 | ethambutol | Not assoc w R |
embC | 4240693 | c.831T>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4240699 | c.837C>G | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embC | 4240726 | c.864G>C | synonymous_variant | 0.4 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.46 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.42 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.37 | ethambutol | |
embC | 4240828 | c.966G>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.36 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.21 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.18 | ethambutol | Uncertain significance |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R |
embC | 4240898 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 0.2 | ethambutol | |
embC | 4240911 | p.Ala350Val | missense_variant | 0.19 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241013 | p.Met384Thr | missense_variant | 0.23 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.25 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.3 | ethambutol | |
embC | 4241032 | c.1170G>C | synonymous_variant | 0.3 | ethambutol | |
embC | 4241038 | c.1176G>C | synonymous_variant | 0.32 | ethambutol | |
embC | 4241047 | c.1185C>G | synonymous_variant | 0.33 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.33 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.34 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.45 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.36 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.38 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.46 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.44 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.47 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.45 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.36 | ethambutol | |
embC | 4241206 | c.1344G>C | synonymous_variant | 0.36 | ethambutol | Not assoc w R - Interim |
embC | 4241218 | c.1356G>C | synonymous_variant | 0.33 | ethambutol | |
embC | 4241230 | c.1368A>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4241233 | c.1371G>C | synonymous_variant | 0.28 | ethambutol | |
embC | 4241395 | p.Lys511Asn | missense_variant | 0.2 | ethambutol | Uncertain significance |
embC | 4241449 | c.1587C>G | synonymous_variant | 0.36 | ethambutol | |
embC | 4241453 | p.Ile531Val | missense_variant | 0.35 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 0.3 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 0.31 | ethambutol | |
embC | 4241530 | c.1668C>A | synonymous_variant | 0.33 | ethambutol | |
embC | 4241536 | c.1674A>G | synonymous_variant | 0.36 | ethambutol | |
embC | 4241539 | c.1677T>C | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embC | 4241545 | c.1683T>C | synonymous_variant | 0.31 | ethambutol | |
embC | 4241548 | c.1686T>C | synonymous_variant | 0.3 | ethambutol | |
embC | 4241551 | c.1689A>G | synonymous_variant | 0.31 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.32 | ethambutol | |
embC | 4241572 | c.1710C>G | synonymous_variant | 0.34 | ethambutol | |
embC | 4241578 | c.1716G>C | synonymous_variant | 0.34 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.35 | ethambutol | |
embC | 4241587 | c.1725C>G | synonymous_variant | 0.39 | ethambutol | |
embC | 4241591 | p.Leu577Val | missense_variant | 0.43 | ethambutol | |
embC | 4241611 | c.1749G>C | synonymous_variant | 0.35 | ethambutol | |
embC | 4241614 | c.1752A>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4241626 | c.1764T>C | synonymous_variant | 0.31 | ethambutol | |
embC | 4241635 | c.1773G>C | synonymous_variant | 0.3 | ethambutol | |
embC | 4241713 | c.1851G>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4241719 | c.1857G>C | synonymous_variant | 0.29 | ethambutol | |
embC | 4241727 | p.Phe622Tyr | missense_variant | 0.39 | ethambutol | |
embC | 4241741 | c.1879_1881delGTCinsCG | frameshift_variant&missense_variant | 0.34 | ethambutol | |
embC | 4241747 | p.Val629Leu | missense_variant | 0.37 | ethambutol | |
embC | 4241750 | p.Leu630Val | missense_variant | 0.35 | ethambutol | |
embC | 4241755 | c.1893C>G | synonymous_variant | 0.41 | ethambutol | |
embC | 4241770 | c.1908T>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
embC | 4241791 | c.1929G>C | synonymous_variant | 0.48 | ethambutol | |
embC | 4241794 | c.1932C>G | synonymous_variant | 0.46 | ethambutol | |
embC | 4241797 | c.1935C>T | synonymous_variant | 0.44 | ethambutol | |
embC | 4241809 | c.1947A>C | synonymous_variant | 0.38 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4242742 | c.-491C>G | upstream_gene_variant | 0.29 | ethambutol | |
embA | 4242748 | c.-485A>G | upstream_gene_variant | 0.29 | ethambutol | |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.29 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.31 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.34 | ethambutol | |
embC | 4242791 | c.2929_2931delGCAinsTC | frameshift_variant&missense_variant | 0.31 | ethambutol | |
embA | 4242796 | c.-437G>C | upstream_gene_variant | 0.33 | ethambutol | |
embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.31 | ethambutol | |
embC | 4242803 | p.Val981Leu | missense_variant | 0.68 | ethambutol | Not assoc w R |
embA | 4242820 | c.-413G>C | upstream_gene_variant | 0.36 | ethambutol | |
embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.35 | ethambutol | |
embA | 4242832 | c.-401A>C | upstream_gene_variant | 0.32 | ethambutol | |
embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.3 | ethambutol | |
embC | 4242841 | c.2979C>T | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.27 | ethambutol | |
embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.28 | ethambutol | |
embA | 4242859 | c.-374C>T | upstream_gene_variant | 0.26 | ethambutol | |
embA | 4242862 | c.-371A>G | upstream_gene_variant | 0.25 | ethambutol | |
embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.27 | ethambutol | |
embC | 4242883 | c.3021C>G | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embA | 4242892 | c.-341G>C | upstream_gene_variant | 0.21 | ethambutol | |
embA | 4245053 | c.1821G>C | synonymous_variant | 0.33 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 0.39 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.49 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.5 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 0.5 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.51 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.62 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.62 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.58 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.58 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.6 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.58 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.53 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4245222 | c.1990_1992delTATinsCG | frameshift_variant&missense_variant | 0.53 | ethambutol | Uncertain significance |
embA | 4245248 | c.2016G>C | synonymous_variant | 0.42 | ethambutol | |
embA | 4245257 | c.2025A>G | synonymous_variant | 0.43 | ethambutol | |
embA | 4245263 | c.2031A>G | synonymous_variant | 0.39 | ethambutol | Not assoc w R - Interim |
embB | 4246184 | c.-330A>C | upstream_gene_variant | 0.21 | ethambutol | |
embB | 4246196 | c.-318C>G | upstream_gene_variant | 0.24 | ethambutol | |
embB | 4246205 | c.-309A>G | upstream_gene_variant | 0.26 | ethambutol | |
embB | 4246211 | c.-303T>C | upstream_gene_variant | 0.27 | ethambutol | |
embB | 4246217 | c.-297G>A | upstream_gene_variant | 0.27 | ethambutol | |
embA | 4246220 | c.2988T>C | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embB | 4246223 | c.-291C>T | upstream_gene_variant | 0.29 | ethambutol | |
embA | 4246227 | p.Ile999Val | missense_variant | 0.3 | ethambutol | |
embA | 4246235 | c.3003G>A | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
embA | 4246242 | p.Gln1004Gly | missense_variant | 0.34 | ethambutol | |
embB | 4246250 | c.-264G>C | upstream_gene_variant | 0.34 | ethambutol | |
embB | 4246256 | c.-258G>T | upstream_gene_variant | 0.41 | ethambutol | |
embA | 4246264 | p.His1011Arg | missense_variant | 0.38 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 0.32 | ethambutol | |
embA | 4246305 | p.Ser1025Glu | missense_variant | 0.25 | ethambutol | |
embA | 4246308 | p.Thr1026Ala | missense_variant | 0.25 | ethambutol | |
embB | 4246316 | c.-198T>G | upstream_gene_variant | 0.27 | ethambutol | |
embB | 4246319 | c.-195G>C | upstream_gene_variant | 0.27 | ethambutol | |
embA | 4246329 | p.Thr1033Leu | missense_variant | 0.2 | ethambutol | |
embB | 4246349 | c.-165C>G | upstream_gene_variant | 0.22 | ethambutol | |
embB | 4247425 | c.912G>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247434 | c.921C>G | synonymous_variant | 0.2 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embB | 4247440 | c.927C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247446 | c.933C>T | synonymous_variant | 0.21 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.4 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.46 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.43 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.4 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.3 | ethambutol | |
embB | 4247761 | c.1248T>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4247773 | c.1260G>A | synonymous_variant | 0.3 | ethambutol | |
embB | 4247776 | c.1263G>T | synonymous_variant | 0.32 | ethambutol | |
embB | 4247797 | c.1284C>G | synonymous_variant | 0.33 | ethambutol | |
embB | 4247800 | c.1287A>T | synonymous_variant | 0.33 | ethambutol | |
embB | 4247803 | c.1290G>C | synonymous_variant | 0.33 | ethambutol | |
embB | 4247815 | c.1302C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4247819 | c.1306_1308delGTTinsAC | frameshift_variant&missense_variant | 0.41 | ethambutol | |
embB | 4247830 | c.1317A>G | synonymous_variant | 0.42 | ethambutol | Not assoc w R - Interim |
embB | 4247836 | c.1323A>G | synonymous_variant | 0.41 | ethambutol | Not assoc w R - Interim |
embB | 4247839 | c.1326G>C | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
embB | 4247866 | c.1353G>C | synonymous_variant | 0.51 | ethambutol | |
embB | 4247875 | c.1362G>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 0.48 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.49 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.46 | ethambutol | Not assoc w R - Interim |
embB | 4247893 | c.1380C>T | synonymous_variant | 0.48 | ethambutol | |
embB | 4247899 | p.Met462Ile | missense_variant | 0.44 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4247932 | c.1419C>G | synonymous_variant | 0.37 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.39 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.37 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.35 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embB | 4247974 | c.1461C>G | synonymous_variant | 0.37 | ethambutol | |
embB | 4248007 | c.1494C>G | synonymous_variant | 0.31 | ethambutol | |
embB | 4248011 | p.Ser500Arg | missense_variant | 0.25 | ethambutol | |
embB | 4248014 | p.Thr501Ala | missense_variant | 0.25 | ethambutol | Uncertain significance |
embB | 4248035 | p.Val508Ile | missense_variant | 0.35 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.33 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.33 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.34 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.36 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.38 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.35 | ethambutol | |
embB | 4248133 | c.1620C>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4248139 | c.1626C>G | synonymous_variant | 0.35 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.35 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.35 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.41 | ethambutol | Not assoc w R - Interim |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.51 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.51 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.51 | ethambutol | |
embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 0.52 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.61 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.45 | ethambutol | |
embB | 4248343 | c.1830G>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.33 | ethambutol | |
embB | 4248355 | c.1842A>G | synonymous_variant | 0.3 | ethambutol | |
embB | 4248358 | c.1845C>G | synonymous_variant | 0.29 | ethambutol | |
embB | 4248361 | c.1848A>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4248362 | p.Ser617Ala | missense_variant | 0.29 | ethambutol | |
embB | 4248373 | c.1860C>G | synonymous_variant | 0.34 | ethambutol | |
embB | 4248386 | c.1873C>A | synonymous_variant | 0.32 | ethambutol | |
embB | 4248407 | p.Leu632Val | missense_variant | 0.32 | ethambutol | |
embB | 4248410 | c.1897_1899delTTCinsCG | frameshift_variant&missense_variant | 0.31 | ethambutol | |
embB | 4248419 | p.Leu636Met | missense_variant | 0.3 | ethambutol | |
embB | 4248425 | c.1912T>C | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embB | 4248430 | c.1917T>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4248432 | p.Trp640Phe | missense_variant | 0.27 | ethambutol | |
embB | 4248457 | c.1944T>C | synonymous_variant | 0.32 | ethambutol | |
embB | 4248472 | c.1959T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248475 | c.1962G>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4249417 | c.2904A>G | synonymous_variant | 0.3 | ethambutol | |
embB | 4249423 | p.Asp970Glu | missense_variant | 0.3 | ethambutol | Uncertain significance |
embB | 4249424 | p.Leu971Met | missense_variant | 0.3 | ethambutol | |
embB | 4249429 | c.2916C>T | synonymous_variant | 0.36 | ethambutol | |
embB | 4249432 | c.2919A>G | synonymous_variant | 0.35 | ethambutol | |
embB | 4249441 | c.2928A>G | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embB | 4249444 | c.2931T>C | synonymous_variant | 0.37 | ethambutol | |
embB | 4249469 | p.Leu986Met | missense_variant | 0.41 | ethambutol | |
embB | 4249486 | c.2973T>G | synonymous_variant | 0.29 | ethambutol | |
embB | 4249498 | c.2985G>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4249521 | p.Ala1003Val | missense_variant | 0.22 | ethambutol | |
embB | 4249525 | c.3012T>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embB | 4249529 | p.Ile1006Val | missense_variant | 0.23 | ethambutol | |
embB | 4249532 | p.Ala1007Thr | missense_variant | 0.24 | ethambutol | Uncertain significance |
embB | 4249537 | c.3024A>G | synonymous_variant | 0.26 | ethambutol | |
embB | 4249543 | c.3030G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4249546 | c.3033G>A | synonymous_variant | 0.21 | ethambutol | |
embB | 4249558 | c.3045A>C | synonymous_variant | 0.2 | ethambutol | |
aftB | 4267200 | p.Trp546Val | missense_variant | 0.2 | ethambutol | |
aftB | 4267214 | c.1623A>C | synonymous_variant | 0.21 | ethambutol | |
aftB | 4267244 | c.1593T>C | synonymous_variant | 0.21 | ethambutol | |
aftB | 4267256 | c.1581C>G | synonymous_variant | 0.2 | ethambutol | |
aftB | 4267262 | c.1575T>C | synonymous_variant | 0.21 | ethambutol | |
aftB | 4267266 | p.Ala524Gly | missense_variant | 0.2 | ethambutol | |
aftB | 4267268 | c.1569T>C | synonymous_variant | 0.2 | ethambutol | |
aftB | 4267274 | c.1563G>C | synonymous_variant | 0.19 | ethambutol | |
aftB | 4267574 | c.1263G>A | synonymous_variant | 0.28 | ethambutol | |
aftB | 4267580 | c.1257G>T | synonymous_variant | 0.33 | ethambutol | |
aftB | 4267604 | c.1233C>G | synonymous_variant | 0.39 | ethambutol | |
aftB | 4267607 | c.1230G>A | synonymous_variant | 0.39 | ethambutol | |
aftB | 4267622 | c.1215G>C | synonymous_variant | 0.37 | ethambutol | |
aftB | 4267625 | c.1212T>C | synonymous_variant | 0.36 | ethambutol | |
aftB | 4267628 | c.1209C>G | synonymous_variant | 0.38 | ethambutol | |
aftB | 4267634 | p.Arg401His | missense_variant | 0.35 | ethambutol | |
aftB | 4268102 | c.735C>G | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
aftB | 4268117 | c.720G>C | synonymous_variant | 0.38 | ethambutol | |
aftB | 4268123 | c.712_714delAGTinsGC | frameshift_variant&synonymous_variant | 0.36 | ethambutol | Uncertain significance |
aftB | 4268129 | c.708T>G | synonymous_variant | 0.39 | ethambutol | |
aftB | 4268138 | c.699A>C | synonymous_variant | 0.41 | ethambutol | Not assoc w R - Interim |
aftB | 4268144 | c.693T>C | synonymous_variant | 0.43 | ethambutol | |
aftB | 4268164 | p.Gln225Glu | missense_variant | 0.44 | ethambutol | |
aftB | 4268169 | p.Ala223Gly | missense_variant | 0.43 | ethambutol | |
aftB | 4268171 | c.666G>C | synonymous_variant | 0.44 | ethambutol | |
aftB | 4268179 | c.658T>C | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
aftB | 4268182 | p.Phe219Leu | missense_variant | 0.43 | ethambutol | |
aftB | 4268183 | c.654A>T | synonymous_variant | 0.43 | ethambutol | |
aftB | 4268193 | p.Leu215Ala | missense_variant | 0.42 | ethambutol | |
aftB | 4268205 | p.Val211Ala | missense_variant | 0.36 | ethambutol | |
aftB | 4268213 | c.624T>G | synonymous_variant | 0.3 | ethambutol | |
aftB | 4268225 | c.612G>C | synonymous_variant | 0.3 | ethambutol | |
aftB | 4268236 | p.Leu201Met | missense_variant | 0.22 | ethambutol | |
ethA | 4328463 | c.-990G>C | upstream_gene_variant | 0.2 | ethionamide | |
ethA | 4328467 | c.-994G>T | upstream_gene_variant | 0.2 | ethionamide | |
ethA | 4328470 | c.-998_-997delAGinsGC | upstream_gene_variant | 0.19 | ethionamide | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin |