TB-Profiler result

Run: SRR7496523
Summary

Run ID: SRR7496523

Sample name:

Date: 2024-04-14T01:30:10.869257

Number of reads: 340583

Percentage reads mapped: 31.02

Median coverage: 10.0

Strain: lineage4.7

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.7 Euro-American (mainly T) None 0.98
lineage4 Euro-American None 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.32 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1218 c.1218C>G synonymous_variant 0.5 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.5 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.59 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.59 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.59 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.59 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.53 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.47 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.47 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.47 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.54 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.54 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 1311 c.1311C>G synonymous_variant 0.54 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.54 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.54 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 0.54 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 1332 c.1332A>C synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.64 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.58 isoniazid
gyrB 6242 p.Arg335Lys missense_variant 0.47 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.3 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6811 c.1572C>T synonymous_variant 0.3 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7078 c.-224A>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.48 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8337 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.61 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8367 c.1066C>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8400 c.1099_1101delGACinsAT frameshift_variant&missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8767 p.Arg489Lys missense_variant 0.64 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.5 levofloxacin
moxifloxacin
mshA 575623 c.276C>G synonymous_variant 0.38 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.38 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.38 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.38 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.38 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 0.38 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.35 ethionamide
isoniazid
mshA 575649 p.Val101Ala missense_variant 0.35 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.35 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.35 ethionamide
isoniazid
mshA 575665 c.318G>A synonymous_variant 0.35 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.5 ethionamide
isoniazid
ccsA 619579 c.-312G>C upstream_gene_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 619584 c.-307A>T upstream_gene_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 619609 c.-282G>T upstream_gene_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.73 capreomycin
amikacin
kanamycin
nusG 734451 c.198G>C synonymous_variant 0.82 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.82 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.4 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.73 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.64 rifampicin
nusG 734596 c.343_345delTTGinsCC frameshift_variant&missense_variant 0.64 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.69 rifampicin
rpoB 760298 c.492G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.78 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760368 c.562_564delTCCinsGG frameshift_variant&missense_variant 0.56 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.84 rifampicin Uncertain significance
rpoB 760390 p.Ser195Thr missense_variant 0.55 rifampicin
rpoB 760400 c.594G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.36 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.59 rifampicin Uncertain significance
rpoB 760412 c.606C>T synonymous_variant 1.0 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.5 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760515 p.Trp237Leu missense_variant 0.35 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760527 p.Gln241Glu missense_variant 0.35 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.94 rifampicin Uncertain significance
rpoB 760568 c.762G>C synonymous_variant 0.35 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.35 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.89 rifampicin
rpoB 760593 c.787_789delGGCinsA frameshift_variant&missense_variant 0.33 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.88 rifampicin
rpoB 760616 p.Asp270Glu missense_variant 0.33 rifampicin Uncertain significance
rpoB 760617 p.Ile271Val missense_variant 0.33 rifampicin
rpoB 760634 c.828T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760640 c.834C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.68 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.46 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.46 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.47 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.53 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760928 c.1122G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.5 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760965 c.1159_1161delATGinsCC frameshift_variant&missense_variant 0.48 rifampicin
rpoB 760973 c.1167G>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.58 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.61 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.83 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.62 rifampicin
rpoB 761178 c.1372_1374delTCAinsAGC synonymous_variant 0.59 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.7 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.68 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>A synonymous_variant 0.68 rifampicin
rpoB 761264 c.1458C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761276 c.1470G>C synonymous_variant 0.52 rifampicin
rpoB 761282 c.1476C>T synonymous_variant 0.48 rifampicin
rpoB 761294 c.1488G>C synonymous_variant 0.45 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.3 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.3 rifampicin
rpoB 761373 p.Val523His missense_variant 0.3 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.33 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.5 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.62 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.62 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.67 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.6 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.57 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.6 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.53 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.56 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.6 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.6 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761969 p.Glu721Asp missense_variant 0.48 rifampicin Uncertain significance
rpoB 761972 c.2166C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 0.48 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.53 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 0.77 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.62 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.77 rifampicin Uncertain significance
rpoB 762128 c.2322G>C synonymous_variant 0.65 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.77 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.77 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762170 c.2364C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.77 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.73 rifampicin
rpoB 762245 c.2439G>T synonymous_variant 0.68 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762299 c.2493G>C synonymous_variant 0.5 rifampicin
rpoB 762305 c.2499G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.44 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762318 p.Ser838Thr missense_variant 0.44 rifampicin
rpoB 762329 c.2523G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762336 c.2530_2532delATTinsGC frameshift_variant&missense_variant 0.33 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.33 rifampicin
rpoB 762344 c.2538G>C synonymous_variant 0.32 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.58 rifampicin
rpoB 762348 c.2542_2543delTCinsAG synonymous_variant 0.37 rifampicin
rpoB 762356 p.Glu850Asp missense_variant 0.35 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.65 rifampicin
rpoB 762368 p.Glu854Asp missense_variant 0.33 rifampicin
rpoB 762369 c.2563_2565delTTGinsCC frameshift_variant&missense_variant 0.67 rifampicin
rpoB 762372 p.Pro856Ala missense_variant 0.33 rifampicin
rpoB 762375 p.Ala857Pro missense_variant 0.33 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.33 rifampicin
rpoC 762392 c.-978G>C upstream_gene_variant 0.33 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.67 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.33 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762426 p.Ser874Gln missense_variant 0.38 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.75 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.38 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762782 c.2976T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.5 rifampicin Uncertain significance
rpoB 762789 p.Leu995Met missense_variant 0.5 rifampicin Uncertain significance
rpoB 762799 p.Ala998Gly missense_variant 0.47 rifampicin Uncertain significance
rpoB 762818 c.3012C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762858 p.Thr1018Ser missense_variant 0.36 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 0.5 rifampicin
rpoB 762881 p.Met1025Ile missense_variant 0.39 rifampicin
rpoC 762887 c.-483G>T upstream_gene_variant 0.41 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762926 c.3120C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.55 rifampicin
rpoB 762989 c.3183G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763025 c.-345C>T upstream_gene_variant 0.26 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.84 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.52 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.5 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.31 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763597 c.228G>A synonymous_variant 0.47 rifampicin
rpoC 763603 c.234C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763609 c.240C>G synonymous_variant 0.47 rifampicin
rpoC 763619 p.Arg84Lys missense_variant 0.5 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.24 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763648 c.279C>T synonymous_variant 0.55 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.55 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.48 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.48 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.74 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.77 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.77 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.75 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.7 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.32 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.47 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.5 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.53 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.53 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.53 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.5 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.5 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.5 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 0.58 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.53 rifampicin
rpoC 763942 c.573C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763948 c.579G>A synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763949 c.580C>A synonymous_variant 0.53 rifampicin
rpoC 763954 c.585C>G synonymous_variant 0.53 rifampicin
rpoC 763963 c.594C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.53 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.53 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.53 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.56 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.57 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.6 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.6 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.56 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.53 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.53 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.44 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.44 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.5 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.4 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>C synonymous_variant 0.46 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.38 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.48 rifampicin
rpoC 764254 c.885G>A synonymous_variant 0.5 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.69 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.5 rifampicin
rpoC 764266 c.897T>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764269 c.900G>C synonymous_variant 0.69 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.54 rifampicin
rpoC 764290 c.921C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.54 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.62 rifampicin
rpoC 764329 c.960C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764341 c.972G>T synonymous_variant 0.67 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.67 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.77 rifampicin
rpoC 764396 c.1027C>T synonymous_variant 0.67 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.71 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.62 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.61 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.74 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 0.59 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>G synonymous_variant 0.61 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.67 rifampicin
rpoC 764506 c.1137C>T synonymous_variant 0.68 rifampicin
rpoC 764509 c.1140G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.58 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.64 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.83 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.54 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.57 rifampicin
rpoC 764605 c.1236G>T synonymous_variant 0.56 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.47 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.48 rifampicin
rpoC 764764 p.His465Gln missense_variant 0.64 rifampicin
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.49 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.69 rifampicin Not assoc w R
rpoC 764824 c.1455T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>T synonymous_variant 0.66 rifampicin
rpoC 764875 c.1506C>T synonymous_variant 0.53 rifampicin
rpoC 764887 c.1518G>T synonymous_variant 0.39 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.4 rifampicin
rpoC 764908 c.1539G>A synonymous_variant 0.41 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.57 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.4 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>C synonymous_variant 0.37 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.38 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 0.41 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.43 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.44 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.5 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.47 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.47 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.54 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.71 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.71 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766174 p.Asn935Lys missense_variant 0.69 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.69 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.69 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766192 c.2823T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 0.67 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 0.8 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.8 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766219 p.Asp950Glu missense_variant 0.8 rifampicin
rpoC 766222 c.2853T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857T>C synonymous_variant 0.8 rifampicin
rpoC 766231 c.2862T>G synonymous_variant 0.8 rifampicin
rpoC 766234 c.2865T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766237 c.2868T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 0.8 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 0.8 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 0.8 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.8 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.64 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.67 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.67 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.64 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.64 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.64 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.67 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.56 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.6 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.67 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.5 rifampicin
rpoC 766542 p.Gly1058Asp missense_variant 0.5 rifampicin
rpoC 766546 p.Glu1059Asp missense_variant 0.5 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.67 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 0.5 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.65 rifampicin
rpoC 766582 c.3213C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766583 p.Gly1072Ser missense_variant 0.56 rifampicin
rpoC 766588 c.3219G>A synonymous_variant 0.48 rifampicin
rpoC 766598 p.Tyr1077Ile missense_variant 0.48 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.57 rifampicin
rpoC 766624 c.3255G>T synonymous_variant 0.55 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.69 rifampicin
rpoC 766633 c.3264G>C synonymous_variant 0.55 rifampicin
rpoC 766645 p.Glu1092Asp missense_variant 0.58 rifampicin Not assoc w R
rpoC 766651 c.3282T>C synonymous_variant 0.52 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.52 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.75 rifampicin
rpoC 766660 c.3291G>T synonymous_variant 0.69 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 0.52 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.77 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.55 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.5 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 0.5 rifampicin
rpoC 766702 c.3333G>C synonymous_variant 0.5 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.47 rifampicin
rpoC 766718 p.Asp1117Asn missense_variant 0.43 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.71 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.69 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.64 rifampicin
rpoC 766775 p.Arg1136Asn missense_variant 0.43 rifampicin
rpoC 766799 p.Ala1144Arg missense_variant 0.38 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.62 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.62 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.62 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.58 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.46 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Ile missense_variant 0.43 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781658 c.99A>G synonymous_variant 0.53 streptomycin
rpsL 781664 c.105C>G synonymous_variant 0.53 streptomycin
rpsL 781670 c.111G>C synonymous_variant 0.5 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.5 streptomycin
rpsL 781685 c.126G>T synonymous_variant 0.5 streptomycin Not assoc w R - Interim
rpsL 781700 c.141G>C synonymous_variant 0.5 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.5 streptomycin
rpsL 781706 c.147T>G synonymous_variant 0.5 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.5 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.5 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 0.5 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.5 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781737 p.Gln60Ser missense_variant 0.5 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.53 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.53 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.47 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.47 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>A synonymous_variant 0.55 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.45 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.47 streptomycin
rpsL 781805 c.246G>C synonymous_variant 0.47 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.47 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.47 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.53 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.47 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.42 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.82 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.47 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.69 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.73 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.65 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.62 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.38 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.57 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.5 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.58 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.77 streptomycin Uncertain significance
rplC 800703 c.-106T>C upstream_gene_variant 0.4 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.4 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.4 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.4 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.46 linezolid
rplC 801300 c.492C>G synonymous_variant 0.32 linezolid
rplC 801309 c.501C>G synonymous_variant 0.29 linezolid
rplC 801312 c.504G>C synonymous_variant 0.29 linezolid
rplC 801321 c.513C>T synonymous_variant 0.29 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.27 linezolid
rplC 801339 c.531T>C synonymous_variant 0.29 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.29 linezolid
rplC 801348 c.540T>G synonymous_variant 0.32 linezolid
rplC 801357 c.549T>C synonymous_variant 0.33 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.38 linezolid
rplC 801402 c.594T>C synonymous_variant 0.29 linezolid
rplC 801405 c.597T>C synonymous_variant 0.29 linezolid
rplC 801423 c.615G>C synonymous_variant 0.35 linezolid
rplC 801426 c.618C>G synonymous_variant 0.35 linezolid
rplC 801427 p.Met207Val missense_variant 0.35 linezolid
rplC 801438 c.630T>C synonymous_variant 0.38 linezolid
rplC 801442 p.Ile212Val missense_variant 0.36 linezolid
fbiC 1303761 c.831T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80delTinsCAG non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471929 n.84C>G non_coding_transcript_exon_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471930 n.85G>C non_coding_transcript_exon_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471931 n.86G>T non_coding_transcript_exon_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1471981 n.136C>G non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472067 n.222G>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453_467delGTCCGGGTTCTCTCGinsCGT non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472445 n.601dupT non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472449 n.604_607delCACGinsGCA non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472463 n.618G>A non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472497 n.652G>A non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472841 n.996G>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472960 n.1115G>A non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472986 n.1141C>T non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473719 n.62G>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473724 n.67T>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473731 n.74T>G non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473732 n.75G>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1473750 n.93C>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473812 n.155G>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473828 n.171_175delGGTGCinsCTGGTGT non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473835 n.179delA non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474265 n.608G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_650delCCTTTTCCTCTCCGGAGGAGinsGTGCAGTCTTTGGTGGCT non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474310 n.655dupG non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474356 n.699T>G non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_782delACCCACACGCGCATACGCGCGTGTGAAinsCATCCCCTTTGGGGTG non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474450 n.793T>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474740 n.1083G>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474747 n.1090C>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475064 n.1407G>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1475066 n.1410_1411insG non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475080 n.1423G>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475081 n.1424C>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945_1948delGGAAinsCAT non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475607 n.1950A>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475609 n.1952C>G non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475614 n.1957A>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475627 n.1970G>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475628 n.1971G>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475633 n.1976G>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475636 n.1979A>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101_2107delACCCGCAinsGTGCCCTTC non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475765 n.2108_2112delAGGGTinsGGGGTGC non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476029 n.2373_2377delACCTC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.77 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.77 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833586 c.45C>T synonymous_variant 0.47 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.67 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.62 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.44 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.61 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.61 pyrazinamide
rpsA 1833623 p.Lys28Ser missense_variant 0.67 pyrazinamide
rpsA 1833658 c.117C>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
rpsA 1833664 c.123C>A synonymous_variant 0.7 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.69 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.69 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 0.69 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.68 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.66 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.68 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.67 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.67 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.69 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.87 pyrazinamide
rpsA 1833763 c.222C>G synonymous_variant 0.72 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.74 pyrazinamide
rpsA 1833782 p.Ser81Asn missense_variant 0.74 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.9 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.71 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.76 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.9 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833862 c.321G>A synonymous_variant 0.71 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.81 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 0.71 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.7 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.8 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.63 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.62 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.62 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.63 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.8 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.63 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.62 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.62 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.6 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.73 pyrazinamide
rpsA 1834066 c.525G>A synonymous_variant 0.44 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834081 c.540C>T synonymous_variant 0.23 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.48 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.48 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834167 p.Thr210Ala missense_variant 0.44 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.35 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.41 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.38 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834298 p.Gln253Ala missense_variant 0.42 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.61 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.46 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834340 c.799_801delATGinsCC frameshift_variant&missense_variant 0.48 pyrazinamide Uncertain significance
rpsA 1834345 c.804C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
rpsA 1834372 c.831G>A synonymous_variant 0.57 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 0.57 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.61 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.83 pyrazinamide
rpsA 1834399 p.His286Gln missense_variant 0.64 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 0.7 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.71 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.84 pyrazinamide
rpsA 1834483 p.Glu314Asp missense_variant 0.7 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834522 c.981C>T synonymous_variant 0.68 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.65 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.59 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.52 pyrazinamide
rpsA 1834612 c.1071G>T synonymous_variant 0.52 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.53 pyrazinamide
rpsA 1834627 c.1086C>T synonymous_variant 0.56 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.65 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.59 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.85 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
ndh 2102227 c.816C>T synonymous_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2102230 c.813G>C synonymous_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.58 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
katG 2156663 c.-552G>A upstream_gene_variant 1.0 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
ahpC 2726348 c.156T>C synonymous_variant 0.33 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.33 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 0.37 isoniazid
ahpC 2726506 p.Thr105Lys missense_variant 0.35 isoniazid Uncertain significance
ahpC 2726508 c.316_318delTTAinsCG frameshift_variant&missense_variant 0.35 isoniazid Uncertain significance
ahpC 2726528 c.336C>G synonymous_variant 0.38 isoniazid
ahpC 2726540 c.348C>G synonymous_variant 0.4 isoniazid
ahpC 2726543 c.351A>G synonymous_variant 0.4 isoniazid
ahpC 2726546 c.354C>G synonymous_variant 0.43 isoniazid
ahpC 2726551 p.Gln120Leu missense_variant 0.46 isoniazid
ahpC 2726556 c.364_366delGCAinsAC frameshift_variant&missense_variant 0.46 isoniazid Uncertain significance
ahpC 2726564 c.372C>G synonymous_variant 0.46 isoniazid Not assoc w R - Interim
ahpC 2726579 c.387T>C synonymous_variant 0.46 isoniazid
ahpC 2726591 c.399C>G synonymous_variant 0.5 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.5 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.5 isoniazid
ahpC 2726601 p.Ile137Leu missense_variant 0.5 isoniazid
Rv2477c 2783035 c.1008G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.73 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 0.54 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin
amikacin Not assoc w R - Interim
Rv2477c 2783149 c.894G>C synonymous_variant 0.54 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783628 p.Ala139Ser missense_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.46 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>G upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066582 c.-392_-391delCCinsGG upstream_gene_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067685 c.261A>C synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.47 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067736 c.208_210delTTCinsCT frameshift_variant&missense_variant 0.53 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.55 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.62 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.63 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.67 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 0.5 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 0.43 para-aminosalicylic_acid
lpqB 3624107 c.804C>T synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624119 c.792C>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624124 p.Leu263Val missense_variant 0.47 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624143 c.768T>C synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.53 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 0.53 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624173 c.738A>C synonymous_variant 0.56 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624179 c.732C>G synonymous_variant 0.59 bedaquiline
rifampicin
lpqB 3624185 c.726C>T synonymous_variant 0.53 bedaquiline
rifampicin
mtrB 3627074 c.-461G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.55 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.55 bedaquiline
rifampicin
rpoA 3877587 c.921A>C synonymous_variant 0.64 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3877599 p.Gln303Ala missense_variant 0.39 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.71 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.43 rifampicin
rpoA 3877623 c.885C>T synonymous_variant 0.43 rifampicin
rpoA 3877629 c.879C>G synonymous_variant 0.43 rifampicin
rpoA 3877638 c.870T>G synonymous_variant 0.43 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.39 rifampicin
rpoA 3877665 c.843C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.74 rifampicin
rpoA 3877674 c.834C>G synonymous_variant 0.39 rifampicin
rpoA 3877677 c.829_831delGCGinsTC frameshift_variant&missense_variant 0.39 rifampicin
rpoA 3877680 c.828G>T synonymous_variant 0.39 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877734 c.774G>C synonymous_variant 0.55 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.55 rifampicin
rpoA 3877743 p.Asp255Glu missense_variant 0.74 rifampicin
rpoA 3877746 c.762G>C synonymous_variant 0.55 rifampicin
rpoA 3877749 c.759C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.58 rifampicin
rpoA 3877765 p.Ala248Ser missense_variant 0.65 rifampicin
rpoA 3877770 c.738A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877803 c.705G>T synonymous_variant 0.62 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877827 c.681C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877842 c.666A>C synonymous_variant 0.62 rifampicin
rpoA 3877845 c.663G>C synonymous_variant 0.59 rifampicin
rpoA 3877848 c.660C>G synonymous_variant 0.76 rifampicin
rpoA 3877854 c.652_654delTTGinsCC frameshift_variant&missense_variant 0.59 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 0.81 rifampicin
rpoA 3877863 c.645G>C synonymous_variant 0.61 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.82 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.81 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.81 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.81 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877898 p.Pro204Ala missense_variant 0.65 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.76 rifampicin
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 0.55 rifampicin
rpoA 3877932 c.576G>C synonymous_variant 0.62 rifampicin
rpoA 3877936 p.Lys191Arg missense_variant 0.67 rifampicin
rpoA 3877938 c.570C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877959 c.549C>G synonymous_variant 0.73 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.71 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 0.71 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878010 c.498C>G synonymous_variant 0.62 rifampicin
rpoA 3878013 c.495T>C synonymous_variant 0.65 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 0.58 rifampicin
rpoA 3878025 c.483C>G synonymous_variant 0.55 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.82 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.82 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.55 rifampicin
rpoA 3878046 c.462T>G synonymous_variant 0.57 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.52 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.8 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.8 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.74 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878102 p.Val136Ile missense_variant 0.55 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.73 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.73 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.7 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.56 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.74 rifampicin Uncertain significance
rpoA 3878142 p.Gly122Asp missense_variant 0.57 rifampicin Uncertain significance
rpoA 3878185 p.Gly108Ala missense_variant 0.5 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Thr missense_variant 0.45 rifampicin
rpoA 3878199 c.309T>C synonymous_variant 0.8 rifampicin
rpoA 3878214 c.294C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878217 c.289_291delCTAinsGG frameshift_variant&missense_variant 0.82 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.25 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.56 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.85 rifampicin
rpoA 3878251 c.256_257delTCinsAG synonymous_variant 0.54 rifampicin
rpoA 3878259 c.249G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878264 p.Ser82Gly missense_variant 0.52 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Ala missense_variant 0.61 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 0.57 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.4 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.5 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878328 c.180G>C synonymous_variant 0.5 rifampicin
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.43 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.92 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.92 rifampicin
rpoA 3878376 c.130_132delTCGinsAGC synonymous_variant 0.92 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.35 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.29 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.36 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.36 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.38 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.41 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.39 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.44 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.44 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.48 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.5 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.5 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.43 rifampicin
clpC1 4038530 p.Glu725Asp missense_variant 0.53 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.47 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.53 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.53 pyrazinamide
clpC1 4038559 p.Ile716Val missense_variant 0.5 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.61 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.64 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.44 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.29 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.27 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.64 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4038677 c.2026_2028delCCGinsGC frameshift_variant&missense_variant 0.45 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.23 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4038701 c.2004G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.69 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.51 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.67 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.71 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.71 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.57 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.72 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.57 pyrazinamide
clpC1 4038810 p.Gln632Ser missense_variant 0.47 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038821 c.1884G>A synonymous_variant 0.23 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038857 c.1848C>T synonymous_variant 0.51 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4038875 c.1830C>G synonymous_variant 0.5 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.5 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.51 pyrazinamide
clpC1 4038905 c.1800A>T synonymous_variant 0.49 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.33 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.45 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.49 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.84 pyrazinamide
clpC1 4038926 c.1779G>T synonymous_variant 0.49 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.89 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038977 c.1728G>A synonymous_variant 0.41 pyrazinamide
clpC1 4038986 p.Asp573Glu missense_variant 0.4 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039019 c.1686G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.76 pyrazinamide
clpC1 4039031 c.1674T>A synonymous_variant 0.5 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.36 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.36 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.7 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.47 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.67 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.59 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCC frameshift_variant&missense_variant 0.47 pyrazinamide
clpC1 4039184 c.1521G>A synonymous_variant 0.47 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.47 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.5 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4039244 c.1461G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.6 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4039517 c.1188C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.83 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.62 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4039583 c.1122C>T synonymous_variant 0.62 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039601 p.Ala368Ser missense_variant 0.62 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039654 p.Thr351Ser missense_variant 0.57 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.58 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039694 c.1011G>T synonymous_variant 0.8 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.59 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.27 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.3 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039787 c.918G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.77 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.83 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.53 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.6 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.3 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.32 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 0.48 pyrazinamide
clpC1 4040002 p.His235Asn missense_variant 0.48 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.5 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.58 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 0.82 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.87 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.87 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.6 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.86 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040138 c.567G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.8 pyrazinamide
clpC1 4040273 c.432T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.55 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.55 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.58 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.47 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.67 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.67 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.54 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.62 pyrazinamide
clpC1 4040501 c.204C>T synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
panD 4044959 c.-678C>G upstream_gene_variant 0.5 pyrazinamide
glpK 4138622 c.1134C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.4 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>A synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4241038 c.1176G>C synonymous_variant 0.43 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.46 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.46 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.46 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.54 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.54 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.58 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.58 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.55 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.37 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.37 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.37 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.33 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.33 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.32 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.32 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.5 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.47 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.5 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.53 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.47 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.37 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.37 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.35 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.35 ethambutol
embB 4247588 c.1075_1077delCTAinsAC frameshift_variant&missense_variant 0.35 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.4 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.38 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.32 ethambutol
embB 4247638 c.1125G>C synonymous_variant 0.32 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.73 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.82 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.75 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.75 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.75 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.75 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.75 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.75 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.75 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.7 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.64 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.64 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.64 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.64 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.64 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.54 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.54 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4248199 c.1686A>G synonymous_variant 0.5 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.5 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.5 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.5 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.5 ethambutol