TB-Profiler result

Run: ERR4769417

Summary

Run ID: ERR4769417

Sample name:

Date: 2024-04-15T06:52:10.645359

Number of reads: 158770

Percentage reads mapped: 5.13

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Pre-XDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Ile486Leu Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Ile486Leu Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6695 p.Ile486Leu missense_variant 0.38 moxifloxacin Uncertain significance Mutation from literature
levofloxacin Uncertain significance Mutation from literature
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6685 c.-617C>A upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6710 p.Ala491Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6722 p.Arg495Lys missense_variant 0.66 levofloxacin
moxifloxacin
gyrB 6725 p.Val496Thr missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6737 p.Thr500Asp missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6784 p.Asp515Glu missense_variant 0.63 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 p.Ile519Val missense_variant 0.63 levofloxacin
moxifloxacin
gyrB 6797 p.Gly520Ser missense_variant 0.63 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6826 c.-476G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>G synonymous_variant 0.53 rifampicin
rpoB 761147 c.1341C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761174 c.1368T>C synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 0.59 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.98 rifampicin
rpoB 761217 c.1411_1413delCCGinsGC frameshift_variant&missense_variant 0.37 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 0.55 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761276 c.1470G>C synonymous_variant 0.41 rifampicin
rpoB 761288 c.1482G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761294 c.1488G>C synonymous_variant 0.41 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761304 p.Val500Ile missense_variant 0.65 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.92 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 0.9 rifampicin
rpoB 761649 c.1843_1845delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761663 c.1857G>C synonymous_variant 1.0 rifampicin
rpoB 761945 c.2139G>C synonymous_variant 0.63 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.61 rifampicin
rpoB 762009 c.2203_2205delCTGinsAC frameshift_variant&missense_variant 0.36 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 p.Glu738Asp missense_variant 0.35 rifampicin
rpoB 762024 p.Val740Met missense_variant 0.33 rifampicin
rpoB 762032 c.2226C>G synonymous_variant 0.68 rifampicin
rpoB 762035 c.2229G>C synonymous_variant 0.68 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762110 c.2304G>C synonymous_variant 0.92 rifampicin
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762128 c.2322G>C synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.97 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.97 rifampicin
rpoB 762146 p.Glu780Asp missense_variant 0.97 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762189 c.2383_2385delATCinsGG frameshift_variant&missense_variant 0.92 rifampicin
rpoB 762209 c.2403C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.96 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 0.67 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.71 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.94 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.79 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762299 c.2493G>C synonymous_variant 0.94 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762336 c.2530_2532delATTinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 1.0 rifampicin
rpoB 762353 c.2547C>T synonymous_variant 0.95 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762368 p.Glu854Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoB 762375 p.Ala857Pro missense_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.97 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.97 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762426 p.Ser874Gln missense_variant 0.95 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.96 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.81 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762485 c.2679G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.94 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.94 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 0.72 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762923 c.3117C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 1.0 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.78 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247_3249delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763058 c.-312C>G upstream_gene_variant 0.71 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 1.0 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 0.72 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 763130 p.Glu1108Asp missense_variant 0.26 rifampicin
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>C upstream_gene_variant 0.4 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763172 c.3366G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.36 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.66 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763501 p.Asp44Glu missense_variant 0.68 rifampicin Uncertain significance
rpoC 763528 c.159G>C synonymous_variant 1.0 rifampicin
rpoC 763531 c.162G>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 1.0 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.72 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763585 c.216C>G synonymous_variant 0.68 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763619 p.Arg84Asn missense_variant 0.27 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.28 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.26 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.28 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.69 rifampicin
rpoC 763727 c.358_360delCTGinsAC frameshift_variant&missense_variant 0.7 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.73 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763747 p.Glu126Asp missense_variant 0.73 rifampicin Uncertain significance
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764112 p.Tyr248Phe missense_variant 0.9 rifampicin
rpoC 764116 c.747C>G synonymous_variant 1.0 rifampicin
rpoC 764126 p.Thr253Ser missense_variant 0.8 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764133 p.Ala255Gly missense_variant 1.0 rifampicin
rpoC 764143 c.774G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764147 p.Ser260Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 764156 p.Lys263Ala missense_variant 0.79 rifampicin
rpoC 764162 c.793_795delATCinsCG frameshift_variant&missense_variant 0.79 rifampicin
rpoC 764177 p.Ile270Leu missense_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764227 c.858G>C synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.81 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764277 p.Gln303Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764291 p.Ser308Asp missense_variant 1.0 rifampicin
rpoC 764297 p.Met310Ala missense_variant 1.0 rifampicin
rpoC 764301 p.Gly311Ala missense_variant 1.0 rifampicin
rpoC 764308 c.939G>C synonymous_variant 1.0 rifampicin
rpoC 764315 p.Ala316Cys missense_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.33 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.42 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>T synonymous_variant 1.0 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764398 c.1029G>C synonymous_variant 0.65 rifampicin
rpoC 764404 c.1035C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 1.0 rifampicin
rpoC 764419 c.1050C>G synonymous_variant 0.67 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764438 p.Leu357Met missense_variant 0.33 rifampicin
rpoC 764443 p.Ile358Met missense_variant 0.67 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>G synonymous_variant 0.34 rifampicin
rpoC 764491 c.1122G>C synonymous_variant 0.65 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.54 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.41 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.59 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>C synonymous_variant 0.55 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.54 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.98 rifampicin
rpoC 764584 c.1215G>C synonymous_variant 0.54 rifampicin
rpoC 764605 c.1236G>T synonymous_variant 0.41 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>A synonymous_variant 0.38 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764638 c.1269C>T synonymous_variant 0.61 rifampicin
rpoC 764647 c.1278C>T synonymous_variant 0.59 rifampicin
rpoC 764650 c.1281G>C synonymous_variant 0.6 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.61 rifampicin
rpoC 764656 c.1287C>G synonymous_variant 0.62 rifampicin
rpoC 764660 c.1291_1293delGTGinsAC frameshift_variant&missense_variant 0.34 rifampicin
rpoC 764665 c.1296C>G synonymous_variant 0.65 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764678 p.Lys437Gln missense_variant 0.75 rifampicin
rpoC 764707 c.1338G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764737 c.1368G>C synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 1.0 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.98 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.97 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.97 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764810 p.Pro481Asp missense_variant 0.94 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 p.Leu497Met missense_variant 1.0 rifampicin
rpoC 764863 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.94 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.93 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764917 c.1548G>C synonymous_variant 1.0 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.97 rifampicin
rpoC 764941 c.1572G>C synonymous_variant 0.9 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>C synonymous_variant 0.92 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.92 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.92 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.92 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672_1674delTTGinsCC frameshift_variant&missense_variant 0.92 rifampicin
rpoC 765047 c.1678T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765400 c.2031G>C synonymous_variant 1.0 rifampicin
rpoC 765404 p.Leu679Val missense_variant 1.0 rifampicin
rpoC 765408 p.Gly680Asp missense_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765435 p.His689Pro missense_variant 1.0 rifampicin
rpoC 765443 p.Val692Arg missense_variant 1.0 rifampicin
rpoC 765453 p.Ala695Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.69 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.76 rifampicin
rpoC 766328 p.Lys987Gln missense_variant 0.75 rifampicin
rpoC 766333 c.2964G>C synonymous_variant 0.77 rifampicin
rpoC 766336 c.2967C>G synonymous_variant 0.72 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.73 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.73 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766399 c.3030G>C synonymous_variant 0.73 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.73 rifampicin
rpoC 766417 c.3048C>T synonymous_variant 0.74 rifampicin
rpoC 766435 p.Glu1022Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 766456 c.3087C>G synonymous_variant 0.69 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>C synonymous_variant 0.92 rifampicin
rpoC 767020 c.3651C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767038 c.3669G>C synonymous_variant 0.91 rifampicin
rpoC 767041 c.3672G>C synonymous_variant 0.92 rifampicin
rpoC 767044 c.3675G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767056 c.3687C>G synonymous_variant 0.83 rifampicin
rpoC 767059 c.3690T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.83 rifampicin
rpoC 767071 c.3702C>G synonymous_variant 0.83 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 0.92 rifampicin
rpoC 767077 c.3708G>C synonymous_variant 0.92 rifampicin
rpoC 767087 p.Cys1240Lys missense_variant 0.91 rifampicin
rpoC 767093 c.3724_3725delAGinsTC synonymous_variant 0.91 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Ile missense_variant 1.0 rifampicin
rpoC 767110 c.3741T>C synonymous_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpsL 781781 c.222G>C synonymous_variant 0.92 streptomycin
rpsL 781802 c.243G>C synonymous_variant 1.0 streptomycin
rpsL 781805 c.246G>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.92 streptomycin
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.92 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781884 p.Asn109Asp missense_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800615 c.-194G>C upstream_gene_variant 0.93 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.94 linezolid
rplC 800630 c.-179G>C upstream_gene_variant 0.91 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.97 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.92 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>G upstream_gene_variant 0.9 linezolid
rplC 800753 c.-56C>T upstream_gene_variant 0.88 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.85 linezolid
rplC 800765 c.-44G>C upstream_gene_variant 0.83 linezolid
fbiC 1304613 c.1683T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304660 p.Tyr577Phe missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304667 c.1737G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304672 p.Val581Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304685 c.1755C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304696 p.Trp589Phe missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304754 p.Glu608Asp missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471927 n.82_85delTTCGinsAGCTTGCT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185_197delGGGATGCATGTCTinsACCGTGAGGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472054 n.210_212delCGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472300 n.455_470delCCGGGTTCTCTCGGATinsTTTC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>A non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472485 n.640delGinsTA non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472497 n.652G>A non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472670 n.825_831delGGGTTTCinsAGGGGT non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.56 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472878 n.1033G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472993 n.1148G>A non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.34 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.34 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.36 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473292 n.1447_1449delGGAinsTGGG non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473782 n.125A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473791 n.134A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473794 n.137A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473801 n.144T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473822 n.165A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473905 n.248T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474178 n.522dupC non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_651delTCCTTTTCCTCTCCGGAGGAGGinsCTTTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474406 n.749T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474416 n.759_782delCACACGCGCATACGCGCGTGTGAAinsG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474450 n.793T>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsGAGAGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.59 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101_2102delACinsG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475768 n.2111_2112delGTinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476088 n.2431A>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.56 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476523 n.2867delC non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476523 n.2867C>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476523 n.2867delC non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476523 n.2867C>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833734 c.193_195delGCCinsTG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833770 p.Asn77Gly missense_variant 1.0 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833782 p.Ser81Glu missense_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.58 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.6 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.37 pyrazinamide Uncertain significance
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 p.Glu97Asp missense_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.41 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.58 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833894 p.Ala118Asp missense_variant 1.0 pyrazinamide
rpsA 1833921 p.Lys127Thr missense_variant 0.33 pyrazinamide
rpsA 1833925 c.384C>T synonymous_variant 0.33 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.61 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.4 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.52 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.57 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.4 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.62 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.38 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.52 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.45 pyrazinamide
rpsA 1834034 c.493_495delATCinsGG frameshift_variant&missense_variant 0.58 pyrazinamide Uncertain significance
rpsA 1834040 p.Lys167Gln missense_variant 0.37 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 1.0 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.42 pyrazinamide
rpsA 1834090 c.549G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.44 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834139 c.598_599delAGinsTC synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834195 c.654G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834243 c.702G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.9 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.9 pyrazinamide Uncertain significance
rpsA 1834336 c.795C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834340 p.Met267Leu missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834361 c.820_822delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834384 c.843A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834408 c.867C>G synonymous_variant 0.88 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834507 c.966C>T synonymous_variant 0.78 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834552 c.1011G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834556 p.Ala339Ser missense_variant 1.0 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 0.83 pyrazinamide
rpsA 1834573 c.1032G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 0.72 pyrazinamide
rpsA 1834603 p.Glu354Asp missense_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.72 pyrazinamide
rpsA 1834612 c.1071G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078_1080delTTGinsCT frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834636 c.1095C>G synonymous_variant 0.65 pyrazinamide
rpsA 1834637 c.1096_1098delAATinsGC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834647 p.Tyr369Phe missense_variant 0.33 pyrazinamide
rpsA 1834667 c.1126_1128delGCGinsAC frameshift_variant&missense_variant 0.44 pyrazinamide Uncertain significance
rpsA 1834683 p.Ala381Gly missense_variant 0.45 pyrazinamide
rpsA 1834687 c.1146C>T synonymous_variant 0.45 pyrazinamide
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.45 pyrazinamide
rpsA 1834700 p.Gln387Ala missense_variant 0.52 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.4 pyrazinamide
rpsA 1834723 c.1182G>A synonymous_variant 0.62 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 c.1192_1194delGCCinsCG frameshift_variant&missense_variant 0.58 pyrazinamide Uncertain significance
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.84 pyrazinamide
clpC1 4038744 p.Thr654Met missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4038755 c.1950G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.78 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.78 pyrazinamide
clpC1 4038788 c.1917G>C synonymous_variant 0.79 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 1.0 pyrazinamide
clpC1 4038810 p.Gln632Ser missense_variant 0.75 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 0.74 pyrazinamide
clpC1 4038872 c.1833C>G synonymous_variant 0.79 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038926 c.1779G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038977 c.1728G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038986 p.Asp573Glu missense_variant 0.76 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039007 c.1698G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039019 c.1686G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039088 c.1617G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039100 c.1605C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039115 p.Lys530Arg missense_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039132 p.Val525Ile missense_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039499 c.1206G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039526 c.1179G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039547 c.1158C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039550 c.1155G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039553 p.Thr384Gln missense_variant 0.87 pyrazinamide
clpC1 4039566 p.Val380Ala missense_variant 0.75 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.94 pyrazinamide Uncertain significance
clpC1 4039574 c.1131G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1117_1119delTCGinsAC frameshift_variant&missense_variant 0.94 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039642 p.Thr355Ser missense_variant 0.95 pyrazinamide
clpC1 4039643 p.His354Leu missense_variant 0.95 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039652 p.Thr351Asn missense_variant 1.0 pyrazinamide
clpC1 4039661 p.Gly348Pro missense_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.98 pyrazinamide
clpC1 4039727 p.Asp326Glu missense_variant 0.76 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.64 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.98 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.45 pyrazinamide
clpC1 4039838 c.865_867delCTGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039871 p.Thr278Gln missense_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039919 c.786C>T synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039940 c.765G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039943 c.762G>T synonymous_variant 0.7 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039960 p.Thr249Ser missense_variant 0.97 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040002 p.His235Asn missense_variant 1.0 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040045 c.660C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 0.89 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040066 c.639G>C synonymous_variant 0.89 pyrazinamide
clpC1 4040090 c.615T>G synonymous_variant 0.96 pyrazinamide
clpC1 4040107 p.Val200Ile missense_variant 0.95 pyrazinamide
clpC1 4040108 c.597G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040116 p.Ile197Val missense_variant 0.89 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.89 pyrazinamide
clpC1 4040123 p.Glu194Ala missense_variant 0.89 pyrazinamide
clpC1 4040132 c.571_573delATCinsGG frameshift_variant&missense_variant 0.89 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040166 p.Ala180Gln missense_variant 0.93 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040276 c.429C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040282 c.423G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040312 c.393G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 1.0 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040351 c.354C>T synonymous_variant 0.95 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040411 c.294T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040480 c.223_225delTCTinsAGC synonymous_variant 1.0 pyrazinamide