TB-Profiler result

Run: ERR4024991
Summary

Run ID: ERR4024991

Sample name:

Date: 2024-10-05T09:52:39.353639

Number of reads: 253563

Percentage reads mapped: 14.84

Median coverage: 4.0

Strain: lineage4.8;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.8 Euro-American (mainly T) RD219 0.08
lineage4.9 Euro-American (H37Rv-like) None 0.68
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embC p.Ala307Thr Uncertain significance Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embC 4240781 p.Ala307Thr missense_variant 0.82 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.9 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.9 isoniazid
gyrB 6745 c.1506T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.8 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.76 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 7126 c.-176G>A upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 7159 c.1920C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7162 c.1923C>T synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>T upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 0.95 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7637 c.336C>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7709 c.408G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8477 c.1176C>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8600 c.1299G>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8840 c.1539C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9296 c.1995T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 0.82 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9317 c.2016G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
fgd1 491472 c.690A>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491490 c.708C>T synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491500 p.Glu240Lys missense_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>C synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491523 c.741G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575704 c.357T>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575725 c.378C>G synonymous_variant 0.9 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 0.92 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>A synonymous_variant 0.92 isoniazid
ethionamide
mshA 575764 c.417C>G synonymous_variant 0.93 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 0.93 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.93 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.96 isoniazid
ethionamide
mshA 575800 c.453G>C synonymous_variant 0.96 isoniazid
ethionamide
mshA 575803 c.456C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.96 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.95 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.94 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.85 isoniazid
ethionamide
mshA 575906 p.Ala187Ser missense_variant 0.7 isoniazid
ethionamide
mshA 575916 p.Asp190Ala missense_variant 0.7 isoniazid
ethionamide
mshA 575920 c.573C>T synonymous_variant 0.7 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.7 isoniazid
ethionamide
mshA 575929 c.582C>G synonymous_variant 0.7 isoniazid
ethionamide
mshA 575935 c.588G>A synonymous_variant 0.7 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.7 isoniazid
ethionamide
mshA 575945 p.Thr200Ala missense_variant 0.7 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.7 isoniazid
ethionamide
ccsA 620649 c.759A>G synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620652 c.762C>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620715 c.825C>T synonymous_variant 0.8 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620764 p.Ala292Ser missense_variant 0.82 kanamycin
capreomycin
amikacin
nusG 734421 c.168A>C synonymous_variant 0.79 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.8 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.9 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.88 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.88 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.9 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.79 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.71 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.57 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 1.0 rifampicin
rpoB 760139 c.333A>T synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760178 c.372G>A synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.82 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.81 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.88 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.88 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.9 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.88 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.89 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.89 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.82 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.81 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.76 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.73 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.73 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.76 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.7 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.73 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.73 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.76 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.77 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.8 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.86 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.82 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.79 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.81 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.81 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.83 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.87 rifampicin
rpoB 760784 c.978G>T synonymous_variant 0.9 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.89 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.89 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.89 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.89 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.92 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.91 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.9 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.9 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.9 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.83 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.83 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.83 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.75 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.75 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.79 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 1.0 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.96 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 0.95 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.94 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.94 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.93 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.8 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.8 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.8 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.77 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.82 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.83 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.82 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.74 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.69 rifampicin
rpoB 761712 p.Val636Ile missense_variant 0.73 rifampicin
rpoB 761727 p.Ser641Ala missense_variant 0.71 rifampicin
rpoB 761736 p.Ile644Val missense_variant 0.73 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 0.76 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.74 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.67 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.67 rifampicin
rpoB 761785 p.Thr660Ser missense_variant 0.67 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.65 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 0.58 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.87 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.88 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.9 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.91 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.81 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 0.83 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.87 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.88 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.88 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 0.88 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.92 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.92 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.92 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.93 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.93 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.93 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.93 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.93 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.96 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.93 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.86 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.8 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.8 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.8 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.64 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.89 rifampicin Uncertain significance
rpoB 762920 c.3114C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.89 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.83 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.84 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.86 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.82 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.77 rifampicin
rpoC 763199 c.-171G>C upstream_gene_variant 0.7 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.71 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.71 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.77 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.77 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.77 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.79 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 0.95 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763588 c.219C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.97 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.92 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.89 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.88 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.85 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.84 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.83 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.87 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.92 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.92 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.92 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.87 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.8 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.81 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.85 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.88 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.88 rifampicin
rpoC 763882 c.513G>A synonymous_variant 0.88 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.88 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.88 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.88 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.88 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.88 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.88 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.86 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.86 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.79 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.77 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.79 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.79 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.91 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.9 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.9 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.91 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.92 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.9 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.85 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.86 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.83 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 0.74 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.71 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.71 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.71 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.71 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.71 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.76 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.76 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.72 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.71 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.75 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.68 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.76 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.95 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.96 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.96 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.96 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.93 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.93 rifampicin
rpoC 764512 c.1143G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.88 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.87 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.86 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.79 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.79 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.82 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.77 rifampicin
rpoC 765016 c.1647C>A synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.73 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765403 c.2034G>C synonymous_variant 1.0 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 1.0 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.84 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.8 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.87 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.92 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.95 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.95 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.9 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.9 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.9 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.83 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 0.8 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.62 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 0.62 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.67 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 0.67 rifampicin
rpoC 766638 p.Lys1090Thr missense_variant 0.67 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.67 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.64 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 0.62 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.68 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.68 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.68 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.67 rifampicin
rpoC 766694 p.Gln1109Asp missense_variant 0.68 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.77 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 0.77 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.81 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.81 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.82 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.82 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.74 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.78 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.78 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.64 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 0.75 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.86 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.96 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.96 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.93 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.93 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.89 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
mmpL5 775817 c.2664T>C synonymous_variant 0.75 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.76 bedaquiline
clofazimine
mmpL5 775829 c.2652C>G synonymous_variant 0.81 bedaquiline
clofazimine
mmpL5 775834 p.Ala883Ser missense_variant 0.75 bedaquiline
clofazimine
mmpL5 775838 c.2643G>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 775851 p.Ser877Thr missense_variant 0.82 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.91 bedaquiline
clofazimine
mmpL5 775865 c.2616T>C synonymous_variant 0.93 bedaquiline
clofazimine
mmpL5 775877 c.2604C>G synonymous_variant 0.86 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.86 bedaquiline
clofazimine
mmpL5 775886 c.2595A>G synonymous_variant 0.95 bedaquiline
clofazimine
mmpL5 775892 c.2589C>T synonymous_variant 0.9 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 0.91 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.9 bedaquiline
clofazimine
mmpL5 775915 p.Ala856Ser missense_variant 0.84 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 0.97 bedaquiline
clofazimine
mmpL5 775921 c.2560C>T synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775924 c.2557C>T synonymous_variant 0.85 bedaquiline
clofazimine Not assoc w R - Interim
mmpL5 775951 c.2530C>T synonymous_variant 0.91 bedaquiline
clofazimine
mmpL5 775955 p.Ile842Val missense_variant 0.45 bedaquiline
clofazimine
mmpL5 775964 p.Ala839Ser missense_variant 0.35 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 775973 c.2506_2508delTTGinsCTC synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.96 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.79 bedaquiline
clofazimine
mmpL5 775997 c.2484T>G synonymous_variant 0.92 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.79 bedaquiline
clofazimine
mmpL5 776005 p.Ile826Leu missense_variant 0.79 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.8 bedaquiline
clofazimine
mmpL5 776030 c.2451G>C synonymous_variant 0.92 bedaquiline
clofazimine
rpsL 781572 p.Gln5Asn missense_variant 0.73 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.65 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.69 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.65 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.65 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.71 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.73 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.79 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.83 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.81 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.85 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.82 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.81 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.81 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 0.81 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 0.81 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 0.83 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.89 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.93 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.94 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.9 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.9 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.9 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.91 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.91 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.94 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.91 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.9 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.9 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.9 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.91 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.9 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.9 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.9 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.9 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.9 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.88 streptomycin Uncertain significance
rplC 800570 c.-239C>G upstream_gene_variant 0.83 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.91 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.91 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.9 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.95 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.9 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.9 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.86 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.74 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.74 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.74 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.74 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.74 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.72 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.71 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.71 linezolid
rplC 800862 c.54C>T synonymous_variant 0.7 linezolid
rplC 800865 c.57A>G synonymous_variant 0.7 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.7 linezolid
rplC 800873 p.Arg22Lys missense_variant 0.7 linezolid
rplC 800877 c.69A>C synonymous_variant 0.7 linezolid
rplC 800880 c.72A>C synonymous_variant 0.7 linezolid
rplC 800889 c.81C>G synonymous_variant 0.77 linezolid
rplC 800892 c.84G>C synonymous_variant 0.77 linezolid
rplC 800895 c.87C>G synonymous_variant 0.79 linezolid
rplC 800904 c.96G>C synonymous_variant 0.75 linezolid
rplC 800916 c.108A>G synonymous_variant 0.75 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.75 linezolid
rplC 800928 c.120C>T synonymous_variant 0.75 linezolid
rplC 800931 c.123G>C synonymous_variant 0.75 linezolid
rplC 800937 c.129A>G synonymous_variant 0.8 linezolid
rplC 800946 c.138T>C synonymous_variant 0.8 linezolid
rplC 800949 c.141T>C synonymous_variant 0.8 linezolid
rplC 800964 c.156G>C synonymous_variant 0.85 linezolid
rplC 800985 c.177A>G synonymous_variant 0.82 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.7 linezolid
rplC 801231 c.423C>T synonymous_variant 0.7 linezolid
rplC 801237 c.429G>A synonymous_variant 0.64 linezolid
rplC 801252 c.444G>C synonymous_variant 0.69 linezolid
rplC 801264 c.456C>T synonymous_variant 0.58 linezolid
rplC 801267 c.459A>C synonymous_variant 0.58 linezolid
rplC 801276 c.468G>C synonymous_variant 0.64 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.58 linezolid
rplC 801285 c.477G>C synonymous_variant 0.58 linezolid
rplC 801307 p.Ala167Ser missense_variant 0.58 linezolid
rplC 801312 c.504G>C synonymous_variant 0.58 linezolid
rplC 801315 c.507G>T synonymous_variant 0.58 linezolid
rplC 801324 c.516T>C synonymous_variant 0.55 linezolid
fbiC 1304526 c.1596T>A synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304541 c.1611C>A synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304567 p.Phe546Tyr missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.86 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.85 pretomanid
delamanid
clofazimine
sigE 1364820 c.408A>G synonymous_variant 0.67 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.77 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.77 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.69 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.69 pyrazinamide
sigE 1364871 c.459C>T synonymous_variant 0.69 pyrazinamide
sigE 1364877 c.465G>T synonymous_variant 0.69 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.71 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.71 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.69 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.77 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.77 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.77 pyrazinamide
sigE 1364931 c.519C>T synonymous_variant 0.71 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.73 pyrazinamide
sigE 1364962 p.Pro184Ala missense_variant 0.6 pyrazinamide
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.92 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.92 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.86 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.95 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_632delCCinsTCGACT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474292 n.635T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rpsA 1833589 c.48A>C synonymous_variant 0.86 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.8 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.8 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.81 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.8 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.76 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.79 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.76 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.77 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.77 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.79 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.81 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.75 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.73 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 0.77 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.8 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.8 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.8 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.8 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.81 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.89 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.89 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.85 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.86 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.81 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.81 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.8 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.8 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.82 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.81 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.84 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.85 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.92 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.92 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.92 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.91 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.94 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.82 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.81 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.81 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.81 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.85 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.83 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.83 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.89 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.88 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.83 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.84 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.84 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.88 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.9 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.88 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.89 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.85 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.85 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.85 pyrazinamide
rpsA 1834771 c.1230G>A synonymous_variant 0.83 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.83 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.83 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834829 p.Ala430Thr missense_variant 0.82 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.73 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.79 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.85 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.85 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.85 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.85 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.85 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.73 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.73 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.64 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.64 linezolid
katG 2155691 c.421T>C synonymous_variant 0.9 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.91 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.83 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.83 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.83 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.83 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.77 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.77 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>T synonymous_variant 0.77 isoniazid
katG 2155764 p.His116Glu missense_variant 0.77 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.77 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.77 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.73 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.93 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.92 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.92 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.92 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.91 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 0.9 isoniazid
kasA 2518636 c.522C>A synonymous_variant 1.0 isoniazid
kasA 2518639 c.525G>T synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.94 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.95 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.95 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.95 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.95 isoniazid
kasA 2518697 p.Cys195Val missense_variant 0.94 isoniazid
kasA 2518708 c.594C>G synonymous_variant 0.9 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.86 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.86 isoniazid
kasA 2518726 c.612G>A synonymous_variant 0.86 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.87 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.83 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.83 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.65 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.59 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.59 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.59 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.59 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.59 isoniazid
kasA 2518813 c.699C>T synonymous_variant 0.76 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.75 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.72 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.69 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.69 isoniazid
Rv2477c 2783386 c.657G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3065058 c.1134C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065061 c.1131C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065064 c.1128G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065082 c.1110G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCGC synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 0.85 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065130 c.1062A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065133 c.1059T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.93 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065154 c.1038G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065160 c.1032C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065166 c.1026C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065925 c.267G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065947 p.Gly82Ala missense_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065997 c.195C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067802 c.144C>G synonymous_variant 0.6 para-aminosalicylic_acid
lpqB 3624636 p.His92Arg missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3624643 p.Ile90Leu missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624646 c.265T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624650 c.261G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624656 c.255C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624673 p.Ala80Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624675 p.Asn79Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624680 c.231T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624701 c.210T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624704 c.207G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624725 c.186G>T synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625111 c.1503G>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625122 c.-212C>A upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625135 c.-225A>C upstream_gene_variant 0.8 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 0.75 rifampicin
bedaquiline
lpqB 3625156 c.-246G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625168 c.-258G>T upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625183 c.-273G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625186 c.-276T>G upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.6 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.6 rifampicin
bedaquiline
lpqB 3625204 c.-294G>C upstream_gene_variant 0.55 rifampicin
bedaquiline
lpqB 3625207 c.-297C>G upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>G upstream_gene_variant 0.55 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.62 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.56 rifampicin
bedaquiline
lpqB 3625615 c.-705G>T upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3625623 p.Thr331Ala missense_variant 0.59 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.59 rifampicin
bedaquiline
mtrB 3625636 p.Ala326Glu missense_variant 0.53 rifampicin
bedaquiline
lpqB 3625639 c.-729C>T upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3625645 c.969C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625648 p.Tyr322His missense_variant 0.56 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 0.59 rifampicin
bedaquiline
lpqB 3625663 c.-753G>A upstream_gene_variant 0.61 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3625753 p.Ala287Gln missense_variant 0.64 rifampicin
bedaquiline
mtrB 3626792 c.-179G>C upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
rpoA 3877638 c.870T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.6 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.67 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.6 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.75 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.85 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.85 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.85 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.86 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 0.88 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.83 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.72 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.75 rifampicin
rpoA 3877875 c.633T>A synonymous_variant 0.76 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.76 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.75 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.78 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.77 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.67 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 0.73 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>A synonymous_variant 0.79 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.81 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.83 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.88 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.89 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.97 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.93 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.93 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>A synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878238 c.270C>T synonymous_variant 1.0 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 1.0 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.95 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.89 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>A synonymous_variant 0.85 rifampicin
clpC1 4038519 p.Arg729Gln missense_variant 0.83 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.67 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.69 pyrazinamide
clpC1 4038584 c.2121G>A synonymous_variant 0.81 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.81 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.79 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.79 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.79 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.79 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.79 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.77 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.85 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.91 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.91 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.91 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.89 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.88 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.89 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.93 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.88 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.88 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.88 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.89 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.89 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039100 c.1605C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.82 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039320 p.Ala462Gly missense_variant 0.84 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.8 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.83 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039361 c.1344C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.83 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.81 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.81 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.79 pyrazinamide
clpC1 4039457 c.1248C>T synonymous_variant 0.79 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.78 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.89 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.88 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.84 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.86 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.96 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.95 pyrazinamide
clpC1 4039832 c.873C>A synonymous_variant 0.95 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039883 c.822G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.88 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.85 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.82 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.88 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040375 c.330G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040390 c.315C>G synonymous_variant 0.77 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.8 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.79 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.85 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.83 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.77 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.77 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.77 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>G synonymous_variant 0.85 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.82 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.8 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.8 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.8 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.8 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.8 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.8 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.8 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.8 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.8 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.8 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.8 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.8 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.8 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
panD 4044138 c.144T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
glpK 4138634 c.1122G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138643 c.1113A>C synonymous_variant 0.83 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138646 c.1110G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138661 c.1095T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138747 c.1009C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138763 c.993G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>A synonymous_variant 0.86 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4240777 c.915G>A synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.82 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.82 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.82 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.82 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.82 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.55 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.55 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.55 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.55 ethambutol
embC 4241074 c.1212G>C synonymous_variant 0.64 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.6 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.53 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.53 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.56 ethambutol
embC 4241125 c.1263G>C synonymous_variant 0.56 ethambutol
embC 4241126 p.Leu422Met missense_variant 0.56 ethambutol
embC 4241129 c.1267C>T synonymous_variant 0.6 ethambutol
embC 4241137 c.1275G>A synonymous_variant 0.6 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.64 ethambutol
embC 4241147 p.Cys429Ile missense_variant 0.64 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.64 ethambutol
embC 4241161 c.1299C>T synonymous_variant 0.64 ethambutol
embC 4241168 c.1306C>T synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4247426 p.Gly305Gln missense_variant 0.82 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.83 ethambutol
embB 4247437 c.924A>C synonymous_variant 0.83 ethambutol
embB 4247440 c.927C>G synonymous_variant 0.83 ethambutol
embB 4247449 c.936C>T synonymous_variant 0.83 ethambutol
embB 4247455 c.942C>T synonymous_variant 0.83 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.85 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.85 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.94 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.9 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.9 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.9 ethambutol
embB 4247536 c.1023C>A synonymous_variant 0.88 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.91 ethambutol
embB 4247555 p.Leu348Ile missense_variant 0.91 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.9 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.9 ethambutol
embB 4247578 c.1065_1066insATCTGT conservative_inframe_insertion 0.9 ethambutol
embB 4247581 c.1069_1074delGCCGGG conservative_inframe_deletion 0.9 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4248112 c.1599C>G synonymous_variant 0.67 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.7 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.7 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.7 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.7 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.91 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.91 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.91 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.92 ethambutol Uncertain significance
embB 4248242 p.Val577Ile missense_variant 0.82 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.8 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.6 ethambutol