TB-Profiler result

Run: ERR5311094

Summary

Run ID: ERR5311094

Sample name:

Date: 2024-03-26T22:55:58.693324

Number of reads: 502591

Percentage reads mapped: 13.29

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.98
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.508_510delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.916_918delTTCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.952_954delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.961_963delGCGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1189_1191delAAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1960_1961insCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1964_1965delGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491290 c.508_510delGTGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303882 c.952_954delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303891 c.961_963delGCGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304119 c.1189_1191delAAAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304890 c.1960_1961insCG frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304893 c.1964_1965delGC frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155693 p.Ser140Asn missense_variant 1.0 isoniazid Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554_1555delTAinsCCTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6796 c.1558_1559delGG frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8201 c.900C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8228 c.927G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8273 c.972C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8591 c.1290C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491031 c.249C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491037 c.255C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491055 c.273C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491172 c.390C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491190 c.408G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491235 p.Asp151Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491251 p.Leu157Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491320 p.Ala180Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491491 p.Pro237Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 c.720G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575618 c.271C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575627 c.280_282delGCAinsTG frameshift_variant&stop_gained 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575635 c.288A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575640 p.Pro98Gln missense_variant 1.0 ethionamide
isoniazid
mshA 575644 c.297G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575652 p.Arg102Pro missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575714 p.Tyr123Asn missense_variant 1.0 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575761 c.414C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575764 c.417C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 1.0 ethionamide
isoniazid
mshA 575806 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575843 p.Arg166Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575856 p.Ala170Gly missense_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575890 c.543C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575906 p.Ala187Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575924 c.577_579delGGAinsTC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575929 c.582C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575932 c.585G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575939 p.Leu198Met missense_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575945 p.Thr200Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575948 p.Val201Ile missense_variant 1.0 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575974 c.627G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575977 c.630G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620577 c.687C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620586 c.696C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620605 c.715_717delGTTinsAA frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620709 c.819G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734484 c.231C>T synonymous_variant 1.0 rifampicin
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760373 c.567C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760400 c.594G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760403 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>T synonymous_variant 1.0 rifampicin
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761075 c.1269G>A synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762078 c.2272C>T synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.96 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.93 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.93 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 1.0 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>T synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763787 p.Asp140Asn missense_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.96 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764843 c.1474_1476delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>G synonymous_variant 1.0 rifampicin
rpoC 765533 p.Tyr722His missense_variant 1.0 rifampicin Uncertain significance
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765898 c.2529C>T synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766425 c.3056_3057insTGTCAC disruptive_inframe_insertion 1.0 rifampicin
rpoC 766428 p.Val1020Gly missense_variant 1.0 rifampicin
rpoC 766434 p.Glu1022Ala missense_variant 1.0 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 1.0 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>A synonymous_variant 1.0 rifampicin
rpoC 767152 c.3783T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Thr missense_variant 0.64 clofazimine
bedaquiline
mmpL5 775871 p.Ile870Met missense_variant 0.64 clofazimine
bedaquiline
mmpL5 775880 p.Asn867Lys missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.75 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775901 c.2580G>A synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 775910 c.2571G>C synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 775921 p.Leu854Val missense_variant 0.9 clofazimine
bedaquiline
mmpL5 775940 c.2541C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775972 p.Ala837Pro missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.95 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsGG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776039 c.2442C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776042 c.2439C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776048 c.2433G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 0.92 clofazimine
bedaquiline
rpsL 781679 c.120C>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>A synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781769 c.210G>A synonymous_variant 1.0 streptomycin
rpsL 781802 c.243G>C synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781895 c.336G>A synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>G synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800543 c.-266C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800549 c.-260G>T upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>A upstream_gene_variant 1.0 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800663 c.-146G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800753 c.-56C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800796 c.-12_-9delTTGG upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 1.0 linezolid
rplC 800808 c.-1A>C upstream_gene_variant 1.0 linezolid Uncertain significance
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800873 p.Arg22Lys missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303497 c.567G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303519 c.589_590delAGinsTC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303827 p.Glu299Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303835 p.Ala302Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303844 p.Ala305Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303861 p.Ile311Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303866 p.Glu312Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303871 p.Tyr314Phe missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303881 c.951G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303903 p.Leu325Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304053 p.Asp375Asn missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiC 1304058 c.1128G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304103 c.1173G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304109 c.1179C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304458 p.Thr510Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304481 c.1551T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304503 c.1573C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304514 c.1584T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304515 p.Ala529Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304652 c.1722C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304665 c.1735C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304688 p.Asp586Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304709 c.1779C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304871 c.1941G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304877 c.1947T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304880 c.1950C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304919 c.1989C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304952 c.2022C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305007 p.Ile693Val missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305043 c.2113_2115delTCAinsAGC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305092 p.Ala721Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364676 c.264C>G synonymous_variant 1.0 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 1.0 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 1.0 pyrazinamide
sigE 1364716 c.304_306delCTCinsTG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355_357delAGGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1364835 c.423C>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 1.0 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364950 c.538_540delGCAinsTC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>G synonymous_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364992 c.580_582delCCGinsGC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.96 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 1.0 pyrazinamide
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673658 c.-544G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673673 c.-529C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673706 c.-496C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.93 ethionamide
isoniazid
inhA 1673718 c.-484G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673750 p.Lys104Arg missense_variant 1.0 ethionamide
isoniazid
fabG1 1673755 p.Glu106Gln missense_variant 1.0 ethionamide
isoniazid
fabG1 1673767 p.Asn110Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1673772 c.-430C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673778 c.-424C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673784 c.-418G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673916 c.-286A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673937 c.-265G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673967 c.-235G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674021 c.-181G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674037 p.Gln200Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674042 c.-160G>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674045 c.-157G>A upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674069 c.-133G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674096 c.-106G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674428 p.Gly76Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674440 p.Glu80Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674483 c.282G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674498 c.297G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674621 c.420C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674669 c.468G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCA frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674745 p.Tyr182Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674765 c.564C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674819 c.618G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674837 c.636C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674840 c.639C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674855 c.654C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 c.682_684delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674927 c.726G>C synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833616 c.75A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833868 c.327C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834573 c.1032G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834649 p.Thr370Ser missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 p.Glu399Asp missense_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Asp missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 1.0 pyrazinamide
katG 2155696 p.Ala139Val missense_variant 0.55 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.46 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.41 isoniazid
katG 2155728 c.384G>T synonymous_variant 1.0 isoniazid
katG 2155738 p.Gly125Ala missense_variant 0.41 isoniazid Uncertain significance
katG 2155740 p.Gly124Ala missense_variant 0.59 isoniazid Uncertain significance
katG 2155743 c.369G>T synonymous_variant 1.0 isoniazid
katG 2155765 p.His116Ile missense_variant 1.0 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.59 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.59 isoniazid
katG 2155779 c.333C>T synonymous_variant 0.31 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.69 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
katG 2155794 c.318G>C synonymous_variant 1.0 isoniazid
katG 2155806 c.306T>C synonymous_variant 0.96 isoniazid
katG 2155809 c.303G>T synonymous_variant 0.7 isoniazid
katG 2155815 c.297G>C synonymous_variant 1.0 isoniazid
katG 2155823 p.His97Asn missense_variant 0.37 isoniazid
katG 2155828 p.Tyr95Phe missense_variant 0.61 isoniazid
katG 2155836 c.276C>G synonymous_variant 0.62 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2519049 p.Gly312Ala missense_variant 1.0 isoniazid
kasA 2519053 c.939G>C synonymous_variant 1.0 isoniazid
kasA 2519056 c.942G>C synonymous_variant 1.0 isoniazid
kasA 2519059 c.945G>C synonymous_variant 1.0 isoniazid
kasA 2519062 c.948T>G synonymous_variant 1.0 isoniazid
kasA 2519068 c.954C>T synonymous_variant 1.0 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 1.0 isoniazid
kasA 2519105 p.Cys331Val missense_variant 1.0 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 1.0 isoniazid
kasA 2519113 p.Gln333His missense_variant 1.0 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 1.0 isoniazid
kasA 2519161 c.1047G>C synonymous_variant 1.0 isoniazid
kasA 2519167 c.1053T>C synonymous_variant 1.0 isoniazid
kasA 2519170 c.1056G>C synonymous_variant 1.0 isoniazid
kasA 2519179 c.1065G>T synonymous_variant 1.0 isoniazid
kasA 2519181 p.Val356Ala missense_variant 1.0 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519195 c.1081_1083delACGinsGC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519209 c.1095C>A synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>G synonymous_variant 1.0 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>C synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
folC 2747272 c.327G>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747287 c.310_312delCCGinsGC frameshift_variant&missense_variant 0.93 para-aminosalicylic_acid
folC 2747290 c.309A>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747311 c.288C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747317 c.282C>A synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747346 c.253C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747349 p.Ala84Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.238_240delCGCinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747365 c.234G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782451 p.Ala531Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782465 c.1578G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782480 c.1563G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1486_1488delTCGinsAGC synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782586 p.Leu486Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782602 c.1441C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782606 c.1435_1437delGGTinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782612 c.1431T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782618 c.1425C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782624 c.1419G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783086 c.957C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783101 c.942G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783668 c.375G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783672 p.Arg124Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 p.Glu120Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2681 2996344 c.-395C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996353 c.-386G>A upstream_gene_variant 1.0 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 1.0 capreomycin
Rv2680 2996366 c.262_264delTATinsCC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2996374 c.-365G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 1.0 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 1.0 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996401 c.-338T>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 1.0 capreomycin
Rv2681 2996407 c.-332C>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 1.0 capreomycin
Rv2680 2996438 c.335_336insCTCC frameshift_variant 1.0 capreomycin Uncertain significance
Rv2680 2996442 c.339_342delTGAA frameshift_variant 1.0 capreomycin Uncertain significance
Rv2681 2996452 c.-287C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996455 c.-284C>T upstream_gene_variant 1.0 capreomycin
Rv2681 2996458 c.-281C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996482 c.-257T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996491 c.-248G>C upstream_gene_variant 1.0 capreomycin
Rv2752c 3065013 c.1179G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065058 c.1134C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065076 c.1116T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065087 c.1105A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid Not assoc w R - Interim
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065094 c.1098C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065097 c.1095C>T synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065126 p.Ser356Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065136 p.Ile352Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065139 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065146 p.Phe349Tyr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065148 c.1044C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065151 c.1041G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065487 c.705T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065505 c.687C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065514 p.Ile226Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065531 p.Thr221Ala missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065532 c.660A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065535 c.657C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065538 c.654G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065541 c.651A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065547 c.645A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065576 p.Ala206Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065583 c.609G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065604 c.588G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065612 p.Thr194Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065622 c.570G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065631 c.561C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.541_543delCGTinsAG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067309 p.Ile213Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067316 c.630A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067330 p.Val206Leu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067337 c.609C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067400 c.546C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067619 c.327A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.283_285delCGCinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067682 c.264G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067760 c.186G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067763 c.181_183delCTCinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067770 p.Gly59Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067803 c.142_143delTCinsAG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067853 c.93C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073881 c.591C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073884 c.588C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073888 p.Ser195Gly missense_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073896 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073992 c.480C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074089 p.Ile128Asn missense_variant 1.0 para-aminosalicylic_acid
thyA 3074094 c.378G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074100 c.372T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074108 c.361_363delACC conservative_inframe_deletion 1.0 para-aminosalicylic_acid
thyA 3074115 c.356_357insCAA disruptive_inframe_insertion 1.0 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 1.0 para-aminosalicylic_acid
ald 3087239 c.420C>G synonymous_variant 1.0 cycloserine
ald 3087251 c.432T>C synonymous_variant 1.0 cycloserine
ald 3087257 c.438T>C synonymous_variant 1.0 cycloserine
ald 3087266 c.447G>C synonymous_variant 1.0 cycloserine
ald 3087272 c.453A>C synonymous_variant 1.0 cycloserine
ald 3087274 p.Thr152Ser missense_variant 1.0 cycloserine
ald 3087278 p.Gln153His missense_variant 1.0 cycloserine
ald 3087281 c.462G>C synonymous_variant 1.0 cycloserine
ald 3087305 c.486G>C synonymous_variant 1.0 cycloserine
ald 3087314 c.495C>T synonymous_variant 1.0 cycloserine
ald 3087319 p.Glu167Ala missense_variant 1.0 cycloserine
ald 3087329 p.Asp170Glu missense_variant 1.0 cycloserine
ald 3087338 c.519G>C synonymous_variant 1.0 cycloserine
ald 3087346 p.Ala176Gly missense_variant 1.0 cycloserine
ald 3087350 c.531C>G synonymous_variant 1.0 cycloserine
ald 3087351 p.Thr178Val missense_variant 1.0 cycloserine
ald 3087368 c.549A>G synonymous_variant 1.0 cycloserine
ald 3087374 c.555C>G synonymous_variant 1.0 cycloserine
ald 3087383 p.Asn188Lys missense_variant 1.0 cycloserine
lpqB 3624646 c.265T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624673 p.Ala80Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624675 p.Asn79Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624683 c.228G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624719 c.192C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624734 c.177A>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625040 p.Thr525Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625072 c.-162G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625075 c.-165G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625078 c.-168G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Lys missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625135 c.-225A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625162 c.-252T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625168 c.-258G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625189 c.-279A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625206 p.Ser470Ala missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625246 c.-336G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625276 c.-366C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625291 p.Glu441Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625312 p.Arg434His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625315 c.-405G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625325 p.His430Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625357 c.-447T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625672 c.-762G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625678 c.-768C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625744 c.870G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.97 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625766 p.Ser283His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625774 c.840G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625801 c.-891G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCA frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625845 p.Ser257Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625846 c.-936G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625852 c.-942A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625864 c.750T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626750 c.-137T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626792 c.-179G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626906 c.442_444delAACinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626909 c.441C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626999 c.-386G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627131 c.-518C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627143 c.-530G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627218 c.-605G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627251 c.-638G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627263 c.-650C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627269 c.-656G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrA 3627307 p.Ala15Pro missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627320 c.-707C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627325 c.-712T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627326 c.-713T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 1.0 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877710 c.798C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877731 c.777G>T synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 p.Ser246His missense_variant 1.0 rifampicin
rpoA 3877776 p.Ile244Ala missense_variant 1.0 rifampicin
rpoA 3877779 p.His243Gln missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878142 p.Gly122Glu missense_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878175 c.333G>C synonymous_variant 1.0 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>A synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 1.0 rifampicin
rpoA 3878259 c.249G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
ddn 3986616 c.-228_-227delAGinsGC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986659 c.-185A>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986664 c.-180A>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 1.0 delamanid
pretomanid
clpC1 4038290 p.Asp805Glu missense_variant 1.0 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038329 c.2376G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038354 p.Gln784Ala missense_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038380 c.2325C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038416 c.2289C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 1.0 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039082 c.1623C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039244 c.1461G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039277 c.1428C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039347 p.Arg453Lys missense_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039439 c.1266C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039566 p.Val380Ala missense_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039575 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039787 c.918G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039808 c.897G>A synonymous_variant 0.92 pyrazinamide
clpC1 4039811 c.894C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039814 c.891C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.92 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039922 c.783C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039988 c.717C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 1.0 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040180 c.525C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040243 c.462C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040255 c.448_450delGCCinsAG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040267