TB-Profiler result

Run: ERR5311094

Summary

Run ID: ERR5311094

Sample name:

Date: 2024-10-04T16:34:24.185165

Number of reads: 502591

Percentage reads mapped: 13.29

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB


Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.98
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.1960_1961insCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1964_1965delGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1304890 c.1960_1961insCG frameshift_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304893 c.1964_1965delGC frameshift_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155693 p.Ser140Asn missense_variant 1.0 isoniazid Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554_1555delTAinsCCTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6796 c.1558_1559delGG frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8201 c.900C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8228 c.927G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8273 c.972C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8552 c.1251C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8591 c.1290C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491007 c.225G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491016 c.234C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491022 c.240C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491031 c.249C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491037 c.255C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491055 c.273C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491133 c.351A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491163 c.381G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491168 p.Phe129Tyr missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491172 c.390C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491190 c.408G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491235 p.Asp151Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491251 p.Leu157Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491290 p.Val170Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491310 c.528C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491316 c.534C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491320 p.Ala180Gln missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491325 c.543G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491337 c.555C>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491343 c.561C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491355 c.573C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491364 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491491 p.Pro237Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491502 c.720G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491509 c.727T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_782delAGinsTC synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491574 c.792C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575618 c.271C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575627 p.Ala94Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575638 c.291T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575640 p.Pro98Gln missense_variant 1.0 isoniazid
ethionamide
mshA 575644 c.297G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575652 p.Arg102Pro missense_variant 1.0 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575689 c.342G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575692 c.345G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575714 p.Tyr123Asn missense_variant 1.0 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.98 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 575761 c.414C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575764 c.417C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575770 c.423G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 1.0 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 1.0 isoniazid
ethionamide
mshA 575806 c.459G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575843 p.Arg166Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575856 p.Ala170Gly missense_variant 1.0 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575878 c.531A>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575890 c.543C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575896 c.549G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575906 p.Ala187Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575916 p.Asp190Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575920 c.573C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575924 p.Gly193Cys missense_variant 1.0 isoniazid
ethionamide
mshA 575929 c.582C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575932 c.585G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575939 p.Leu198Met missense_variant 1.0 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575945 p.Thr200Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575948 p.Val201Ile missense_variant 1.0 isoniazid
ethionamide
mshA 575953 c.606G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575965 c.618C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575974 c.627G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575977 c.630G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620385 c.495G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620577 c.687C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620586 c.696C>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620589 c.699G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620605 p.Val239Ile missense_variant 1.0 kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
ccsA 620613 c.723C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620634 c.744C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620646 c.756G>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620664 c.774C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620709 c.819G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734484 c.231C>T synonymous_variant 1.0 rifampicin
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760356 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760373 c.567C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760400 c.594G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760403 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>T synonymous_variant 1.0 rifampicin
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761075 c.1269G>A synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ser missense_variant 1.0 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762078 c.2272C>T synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762156 p.Val784Ile missense_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.96 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.93 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.93 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 1.0 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>T synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763787 p.Asp140Asn missense_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.96 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764843 p.Ala492Ser missense_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>G synonymous_variant 1.0 rifampicin
rpoC 765533 p.Tyr722His missense_variant 1.0 rifampicin Uncertain significance
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765898 c.2529C>T synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766425 c.3056_3057insTGTCAC disruptive_inframe_insertion 1.0 rifampicin
rpoC 766428 p.Val1020Gly missense_variant 1.0 rifampicin
rpoC 766434 p.Glu1022Ala missense_variant 1.0 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 1.0 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>A synonymous_variant 1.0 rifampicin
rpoC 767152 c.3783T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775864 p.Ala873Thr missense_variant 0.64 bedaquiline
clofazimine
mmpL5 775871 p.Ile870Met missense_variant 0.64 bedaquiline
clofazimine
mmpL5 775880 p.Asn867Lys missense_variant 0.69 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.75 bedaquiline
clofazimine
mmpL5 775901 c.2580G>A synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 775910 c.2571G>C synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 0.68 bedaquiline
clofazimine
mmpL5 775921 p.Leu854Val missense_variant 0.9 bedaquiline
clofazimine
mmpL5 775940 c.2541C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775943 c.2538C>G synonymous_variant 0.93 bedaquiline
clofazimine
mmpL5 775946 c.2535C>G synonymous_variant 0.96 bedaquiline
clofazimine
mmpL5 775961 c.2520C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775972 p.Ala837Pro missense_variant 1.0 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 1.0 bedaquiline
clofazimine
mmpL5 775991 c.2490G>A synonymous_variant 0.95 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.95 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776015 p.Ile822Val missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776039 c.2442C>A synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776042 c.2439C>T synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776048 c.2433G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776060 c.2421C>G synonymous_variant 0.92 bedaquiline
clofazimine
rpsL 781679 c.120C>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>A synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781769 c.210G>A synonymous_variant 1.0 streptomycin
rpsL 781802 c.243G>C synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781895 c.336G>A synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>G synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800543 c.-266C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800549 c.-260G>T upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>A upstream_gene_variant 1.0 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800663 c.-146G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800753 c.-56C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800796 c.-12_-9delTTGG upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>A upstream_gene_variant 1.0 linezolid
rplC 800808 c.-1A>C upstream_gene_variant 1.0 linezolid Uncertain significance
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800873 p.Arg22Lys missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
fbiC 1303492 c.562T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303497 c.567G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303519 c.589_590delAGinsTC synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303531 p.Met201Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303581 c.651G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303587 c.657G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303594 c.664C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303638 c.708A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303644 c.714G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303689 c.759T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303794 c.864A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303827 p.Glu299Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303835 p.Ala302Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303844 p.Ala305Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303861 p.Ile311Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303866 p.Glu312Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303871 p.Tyr314Phe missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303881 c.951G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303882 p.Val318Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303891 p.Ala321Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303903 p.Leu325Met missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303912 p.GlyMet328LysVal missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304034 c.1104A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304050 c.1120T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304053 p.Asp375Asn missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1304058 c.1128G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304059 c.1129C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304097 c.1167G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304103 c.1173G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304106 c.1176G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304109 c.1179C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304115 c.1185A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304118 c.1188C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304119 p.Lys397Gln missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304133 c.1203G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304458 p.Thr510Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304465 p.Gly512Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304481 c.1551T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304487 c.1557C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304496 c.1566T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304503 c.1573C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304514 c.1584T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304515 p.Ala529Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304637 c.1707G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304652 c.1722C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304665 c.1735C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304688 p.Asp586Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304709 c.1779C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304751 c.1821C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304754 c.1824G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304763 c.1833C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304772 c.1842C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304784 c.1854T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304871 c.1941G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304877 c.1947T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304880 c.1950C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304883 c.1953G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304919 c.1989C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304925 c.1995G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304952 c.2022C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305007 p.Ile693Val missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1305012 c.2082G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305043 c.2113_2115delTCAinsAGC synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305063 c.2133G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305066 c.2136T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305069 c.2139G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305074 p.Ser715Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305078 c.2148A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305092 p.Ala721Gly missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364676 c.264C>G synonymous_variant 1.0 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 1.0 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 1.0 pyrazinamide
sigE 1364716 c.304_306delCTCinsTTG synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355_357delAGGinsCGC synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364818 c.406_408delCTAinsTTG synonymous_variant 1.0 pyrazinamide
sigE 1364835 c.423C>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 1.0 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 1.0 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 1.0 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>G synonymous_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364992 p.Pro194Ala missense_variant 1.0 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.96 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 1.0 pyrazinamide
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673658 c.-544G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673673 c.-529C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673706 c.-496C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 0.93 isoniazid
ethionamide
inhA 1673718 c.-484G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673750 c.-452A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673755 c.-447G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673767 c.-435A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673772 c.-430C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673778 c.-424C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673784 c.-418G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673916 c.-286A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673937 c.-265G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673967 c.-235G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673988 c.-214G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674021 c.-181G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674037 c.-165C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674042 c.-160G>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
inhA 1674045 c.-157G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674049 c.-153_-151delCAAinsGAC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674063 c.-139G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674069 c.-133G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674096 c.-106G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674428 p.Gly76Asp missense_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674440 p.Glu80Ala missense_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674450 c.249G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674452 p.Ala84Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674483 c.282G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674489 c.288G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674498 c.297G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674507 c.306G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674579 c.378G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674600 c.399G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674601 p.Leu134Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674621 c.420C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674628 p.Ser143Gly missense_variant 1.0 isoniazid
ethionamide
inhA 1674639 c.438C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674663 c.462G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674669 c.468G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674714 c.513C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517_519delAGGinsCGA synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674726 c.525G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674745 p.Tyr182Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674750 c.549T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674756 c.555T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674759 c.558G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674765 c.564C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674771 c.570C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674819 c.618G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674837 c.636C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674840 c.639C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 1.0 isoniazid
ethionamide
inhA 1674855 c.654C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674858 c.657G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674876 c.675C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674883 p.Ile228Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 1.0 isoniazid
ethionamide
inhA 1674909 c.708G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674927 c.726G>C synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833616 c.75A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833868 c.327C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834573 c.1032G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834649 p.Thr370Ser missense_variant 1.0 pyrazinamide
rpsA 1834663 p.AspProAla374GluAlaTrp missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 p.Glu399Asp missense_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Asp missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 1.0 pyrazinamide
katG 2155696 p.Ala139Val missense_variant 0.55 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.46 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.41 isoniazid
katG 2155728 c.384G>T synonymous_variant 1.0 isoniazid
katG 2155738 p.Gly125Ala missense_variant 0.41 isoniazid Uncertain significance
katG 2155740 p.Gly124Ala missense_variant 0.59 isoniazid Uncertain significance
katG 2155743 c.369G>T synonymous_variant 1.0 isoniazid
katG 2155765 p.His116Ile missense_variant 1.0 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.59 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.59 isoniazid
katG 2155779 c.333C>T synonymous_variant 0.31 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.69 isoniazid
katG 2155785 c.327T>C synonymous_variant 1.0 isoniazid
katG 2155794 c.318G>C synonymous_variant 1.0 isoniazid
katG 2155806 c.306T>C synonymous_variant 0.96 isoniazid
katG 2155809 c.303G>T synonymous_variant 0.7 isoniazid
katG 2155815 c.297G>C synonymous_variant 1.0 isoniazid
katG 2155823 p.His97Asn missense_variant 0.37 isoniazid
katG 2155828 p.Tyr95Phe missense_variant 0.61 isoniazid
katG 2155836 c.276C>G synonymous_variant 0.62 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2519049 p.Gly312Ala missense_variant 1.0 isoniazid
kasA 2519053 c.939G>C synonymous_variant 1.0 isoniazid
kasA 2519056 c.942G>C synonymous_variant 1.0 isoniazid
kasA 2519059 c.945G>C synonymous_variant 1.0 isoniazid
kasA 2519062 c.948T>G synonymous_variant 1.0 isoniazid
kasA 2519068 c.954C>T synonymous_variant 1.0 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 1.0 isoniazid
kasA 2519105 p.Cys331Val missense_variant 1.0 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 1.0 isoniazid
kasA 2519113 p.Gln333His missense_variant 1.0 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 1.0 isoniazid
kasA 2519161 c.1047G>C synonymous_variant 1.0 isoniazid
kasA 2519167 c.1053T>C synonymous_variant 1.0 isoniazid
kasA 2519170 c.1056G>C synonymous_variant 1.0 isoniazid
kasA 2519179 c.1065G>T synonymous_variant 1.0 isoniazid
kasA 2519181 p.Val356Ala missense_variant 1.0 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519195 p.Thr361Ala missense_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519209 c.1095C>A synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>G synonymous_variant 1.0 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>C synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
folC 2747272 c.327G>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747287 p.Pro104Ala missense_variant 0.93 para-aminosalicylic_acid
folC 2747290 c.309A>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747311 c.288C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747317 c.282C>A synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747341 p.Val86Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747346 c.253C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747349 p.Ala84Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.238_240delCGCinsAGG synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747365 c.234G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782451 p.Ala531Gly missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782453 c.1590C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782465 c.1578G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782480 c.1563G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782496 p.Asp516Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1486_1488delTCGinsAGC synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782586 p.Leu486Gln missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782591 c.1452T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782602 c.1441C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782606 p.Gly479Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782612 c.1431T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782618 c.1425C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782624 c.1419G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783086 c.957C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783101 c.942G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783626 p.Ala139Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783668 c.375G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783672 p.Arg124Lys missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 p.Glu120Asp missense_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2681 2996344 c.-395C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996353 c.-386G>A upstream_gene_variant 1.0 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 1.0 capreomycin
Rv2680 2996366 p.Tyr88His missense_variant 1.0 capreomycin
Rv2681 2996374 c.-365G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 1.0 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 1.0 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996401 c.-338T>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 1.0 capreomycin
Rv2681 2996407 c.-332C>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 1.0 capreomycin
Rv2680 2996438 c.335_336insCTCC frameshift_variant 1.0 capreomycin Uncertain significance
Rv2680 2996442 c.339_342delTGAA frameshift_variant 1.0 capreomycin Uncertain significance
Rv2681 2996452 c.-287C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996455 c.-284C>T upstream_gene_variant 1.0 capreomycin
Rv2681 2996458 c.-281C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996482 c.-257T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996491 c.-248G>C upstream_gene_variant 1.0 capreomycin
Rv2752c 3065013 c.1179G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065058 c.1134C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065076 c.1116T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065087 c.1105A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065094 c.1098C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065097 c.1095C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065109 c.1081_1083delAGAinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065130 c.1062A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065133 c.1059T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065136 p.Ile352Met missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065139 c.1053C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065146 p.Phe349Tyr missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065148 c.1044C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065151 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065487 c.705T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065505 c.687C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065514 p.Ile226Met missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065531 p.Thr221Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065532 c.660A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065535 c.657C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065538 c.654G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065541 c.651A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065547 c.645A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065553 c.639A>G synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065576 p.Ala206Ser missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065580 c.612G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065583 c.609G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065604 c.588G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065622 c.570G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065631 c.561C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065634 c.558G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065637 c.555A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065649 c.541_543delCGTinsAGG synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065661 c.531A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067309 p.Ile213Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067316 c.630A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067330 p.Val206Leu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067337 c.609C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067400 c.546C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067619 c.327A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.283_285delCGCinsAGG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067682 c.264G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067760 c.186G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067763 p.Leu61Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067770 p.Gly59Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067803 c.142_143delTCinsAG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067853 c.93C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073881 c.591C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073884 c.588C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073888 p.Ser195Gly missense_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073896 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073992 c.480C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074089 p.Ile128Asn missense_variant 1.0 para-aminosalicylic_acid
thyA 3074094 c.378G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074100 c.372T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074108 c.361_363delACC conservative_inframe_deletion 1.0 para-aminosalicylic_acid
thyA 3074115 c.356_357insCAA disruptive_inframe_insertion 1.0 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 1.0 para-aminosalicylic_acid
ald 3087239 c.420C>G synonymous_variant 1.0 cycloserine
ald 3087251 c.432T>C synonymous_variant 1.0 cycloserine
ald 3087257 c.438T>C synonymous_variant 1.0 cycloserine
ald 3087266 c.447G>C synonymous_variant 1.0 cycloserine
ald 3087272 c.453A>C synonymous_variant 1.0 cycloserine
ald 3087274 p.Thr152Ser missense_variant 1.0 cycloserine
ald 3087278 p.Gln153His missense_variant 1.0 cycloserine
ald 3087281 c.462G>C synonymous_variant 1.0 cycloserine
ald 3087305 c.486G>C synonymous_variant 1.0 cycloserine
ald 3087314 c.495C>T synonymous_variant 1.0 cycloserine
ald 3087319 p.Glu167Ala missense_variant 1.0 cycloserine
ald 3087329 p.Asp170Glu missense_variant 1.0 cycloserine
ald 3087338 c.519G>C synonymous_variant 1.0 cycloserine
ald 3087346 p.Ala176Gly missense_variant 1.0 cycloserine
ald 3087350 c.531C>G synonymous_variant 1.0 cycloserine
ald 3087351 p.Thr178Val missense_variant 1.0 cycloserine
ald 3087368 c.549A>G synonymous_variant 1.0 cycloserine
ald 3087374 c.555C>G synonymous_variant 1.0 cycloserine
ald 3087383 p.Asn188Lys missense_variant 1.0 cycloserine
lpqB 3624646 c.265T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624673 p.Ala80Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624675 p.Asn79Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624680 c.231T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624683 c.228G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624719 c.192C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624734 c.177A>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625040 p.Thr525Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3625069 c.-159T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625072 c.-162G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625075 c.-165G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625078 c.-168G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625095 p.Glu507Lys missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625102 c.-192A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625117 c.-207T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625135 c.-225A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625162 c.-252T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625168 c.-258G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625189 c.-279A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625206 p.Ser470Ala missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625246 c.-336G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625252 c.1362G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625276 c.-366C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625291 p.Glu441Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625312 p.Arg434His missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625315 c.-405G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625321 c.1293A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625325 p.His430Arg missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625351 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625357 c.-447T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625672 c.-762G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625678 c.-768C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625744 c.870G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.97 rifampicin Uncertain significance
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625766 p.Ser283His missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625801 c.-891G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625804 c.-896_-894delAGGinsCGA upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625845 p.Ser257Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625846 c.-936G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625852 c.-942A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625864 c.750T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626711 p.Thr213Gln missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626750 c.-137T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGT upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626786 c.-173A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626792 c.-179G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.98 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626906 p.Asn148Gln missense_variant 1.0 rifampicin
bedaquiline
mtrA 3626909 c.441C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626930 c.-317A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626939 p.Glu137Asp missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626978 p.Asp124Glu missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626999 c.-386G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627041 p.Ile103Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627062 c.-449G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627131 c.-518C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627143 c.-530G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627218 c.-605G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627251 c.-638G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627263 c.-650C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627269 c.-656G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627272 c.-659G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTC upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627307 p.Ala15Pro missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627320 c.-707C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627325 c.-712T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627326 c.-713T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877569 p.Pro313Ala missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 1.0 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877710 c.798C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877731 c.777G>T synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 p.Ser246His missense_variant 1.0 rifampicin
rpoA 3877776 p.Ile244Ala missense_variant 1.0 rifampicin
rpoA 3877779 p.His243Gln missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878142 p.Gly122Glu missense_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878175 c.333G>C synonymous_variant 1.0 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>A synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 1.0 rifampicin
rpoA 3878259 c.249G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
ddn 3986616 c.-228_-227delAGinsGC upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986659 c.-185A>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986661 c.-183C>A upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986664 c.-180A>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986690 c.-154C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986696 c.-148G>C upstream_gene_variant 1.0 pretomanid
delamanid
clpC1 4038290 p.Asp805Glu missense_variant 1.0 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038308 p.Val799Leu missense_variant 1.0 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038329 c.2376G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038354 p.Gln784Ala missense_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038380 c.2325C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038416 c.2289C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 1.0 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039082 c.1623C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039244 c.1461G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039277 c.1428C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039347 p.Arg453Lys missense_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039439 c.1266C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039566 p.Val380Ala missense_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039575 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039787 c.918G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039808 c.897G>A synonymous_variant 0.92 pyrazinamide
clpC1 4039811 c.894C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039814 c.891C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.92 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039922 c.783C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039988 c.717C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 1.0 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040180 c.525C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040243 c.462C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040255 p.Ala150Thr missense_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040315 c.390G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040318 c.387C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040336