TB-Profiler result

Run: SRR12708409
Summary

Run ID: SRR12708409

Sample name:

Date: 2024-10-04T11:42:12.439251

Number of reads: 518001

Percentage reads mapped: 32.0

Median coverage: 13.0

Strain: lineage4.3.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.3 Euro-American (LAM) None 1.0
lineage4 Euro-American None 1.0
lineage4.3.3 Euro-American (LAM) RD115 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.Met306Val Assoc w R
pyrazinamide pncA p.Gly132Ala Assoc w R
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethA c.-11A>G Uncertain significance Mutation from literature
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
pncA 2288847 p.Gly132Ala missense_variant 1.0 pyrazinamide Assoc w R
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol Assoc w R
ethA 4327484 c.-11A>G upstream_gene_variant 1.0 ethionamide Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.17 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.16 isoniazid
dnaA 714 c.714C>T synonymous_variant 0.21 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.21 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.18 isoniazid Not assoc w R - Interim
dnaA 748 p.Leu250Phe missense_variant 0.16 isoniazid
gyrA 6655 c.-647T>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6772 c.1533C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.33 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6808 c.1569C>G synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7051 p.Glu604Asp missense_variant 0.2 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7078 c.-224A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7123 c.-179C>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrB 7126 c.1887G>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7129 c.-173T>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7156 c.1917C>T synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8040 p.Gly247Ser missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491082 c.300T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 491112 c.330G>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491137 p.Glu119Ile missense_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>T synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491172 c.390C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
nusG 734407 p.Val52Ile missense_variant 0.5 rifampicin
nusG 734415 c.162C>G synonymous_variant 0.35 rifampicin
nusG 734418 c.165C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>C synonymous_variant 0.39 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.39 rifampicin
nusG 734445 c.192C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
nusG 734451 c.198G>C synonymous_variant 0.29 rifampicin
nusG 734452 p.Glu67Gln missense_variant 0.33 rifampicin Uncertain significance
nusG 734460 c.207G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>C synonymous_variant 0.33 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
nusG 734497 p.Val82Ile missense_variant 0.39 rifampicin Uncertain significance
nusG 734502 c.249G>A synonymous_variant 0.32 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
nusG 734535 c.282C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
nusG 734571 c.318C>G synonymous_variant 0.27 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
nusG 734820 c.567A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 0.5 rifampicin
nusG 734834 p.Met194Thr missense_variant 0.36 rifampicin Uncertain significance
nusG 734841 c.588G>T synonymous_variant 0.42 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.43 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.45 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.45 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.48 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.53 rifampicin
nusG 734864 p.Thr204Ser missense_variant 0.42 rifampicin
nusG 734889 c.636G>A synonymous_variant 0.35 rifampicin
nusG 734893 p.Lys214Arg missense_variant 0.35 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.41 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760400 c.594G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.35 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.44 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.5 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.46 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.46 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.46 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.44 rifampicin
rpoB 760588 p.Thr261Met missense_variant 0.5 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.68 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.49 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.49 rifampicin
rpoB 760608 c.802C>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.74 rifampicin
rpoB 760634 c.828T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.28 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760659 c.853_855delTCAinsAGC synonymous_variant 0.27 rifampicin
rpoB 760668 p.Thr288Ala missense_variant 0.5 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.65 rifampicin
rpoB 760727 c.921C>G synonymous_variant 0.41 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760736 c.930C>G synonymous_variant 0.5 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.69 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.42 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.45 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.45 rifampicin
rpoB 760943 c.1137C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.52 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.78 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.8 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.83 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.85 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761178 p.Ser458Thr missense_variant 0.48 rifampicin Uncertain significance
rpoB 761186 p.Glu460Asp missense_variant 0.46 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.45 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761537 c.1731C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761657 c.1851C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.32 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>A synonymous_variant 0.56 rifampicin
rpoB 761955 p.Ile717Val missense_variant 0.67 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762002 c.2196C>G synonymous_variant 0.22 rifampicin
rpoB 762003 p.Asn733Gln missense_variant 0.22 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762011 c.2205G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762026 c.2220G>C synonymous_variant 0.31 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.29 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762098 c.2292C>G synonymous_variant 0.23 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.52 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.38 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.42 rifampicin
rpoB 762134 c.2328C>A synonymous_variant 0.43 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.44 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.44 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762323 c.2517C>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.67 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.63 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.58 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.61 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.61 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.35 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 0.21 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.19 rifampicin
rpoB 763082 c.3276C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.17 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.17 rifampicin
rpoB 763145 c.3339G>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 763193 c.3387C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.32 rifampicin
rpoC 763411 c.42T>C synonymous_variant 0.32 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763430 c.61_63delAGGinsCGC synonymous_variant 0.32 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.31 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763450 c.81G>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.31 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>G synonymous_variant 0.33 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.41 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.37 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.37 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.77 rifampicin
rpoC 763732 c.363C>A synonymous_variant 0.38 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.74 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.73 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.43 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.58 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.5 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.47 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763933 c.564C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.52 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.61 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.45 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.54 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.62 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.63 rifampicin
rpoC 764054 c.685C>T synonymous_variant 0.5 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.58 rifampicin
rpoC 764083 p.Asn239Val missense_variant 0.48 rifampicin
rpoC 764095 c.726C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764098 c.729A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.52 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764534 p.Arg389Ser missense_variant 0.46 rifampicin
rpoC 764539 c.1170C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>A synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.21 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.24 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.3 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.24 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.22 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.63 rifampicin Not assoc w R
rpoC 764810 p.Pro481Ala missense_variant 0.64 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.41 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.42 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.65 rifampicin Not assoc w R
rpoC 765403 c.2034G>C synonymous_variant 0.56 rifampicin
rpoC 765405 p.Leu679His missense_variant 0.56 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765449 p.Ala694Ser missense_variant 0.45 rifampicin Uncertain significance
rpoC 765454 c.2085C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765469 c.2100G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>G synonymous_variant 0.41 rifampicin
rpoC 765480 p.Tyr704Phe missense_variant 0.41 rifampicin Uncertain significance
rpoC 765861 p.Phe831Tyr missense_variant 0.29 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.33 rifampicin Uncertain significance
rpoC 765907 c.2538G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 0.5 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.48 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 766435 p.Glu1022Asp missense_variant 0.38 rifampicin Uncertain significance
rpoC 766963 c.3594T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>T synonymous_variant 0.28 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 0.27 rifampicin
rpoC 767080 c.3711G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767093 c.3724_3726delAGCinsTCG synonymous_variant 0.27 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Ile missense_variant 0.3 rifampicin
rpoC 767113 c.3744G>C synonymous_variant 0.32 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767173 c.3804C>G synonymous_variant 0.33 rifampicin
rpoC 767179 c.3810C>T synonymous_variant 0.45 rifampicin
rpoC 767180 p.Ala1271Thr missense_variant 0.36 rifampicin
rpoC 767180 p.Ala1271Ser missense_variant 0.45 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.5 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.35 rifampicin
rpoC 767230 c.3861G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781572 p.Gln5Asn missense_variant 0.42 streptomycin
rpsL 781586 c.27C>T synonymous_variant 0.52 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.55 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.61 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.58 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.56 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.54 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.56 streptomycin
rpsL 781658 c.99A>C synonymous_variant 0.58 streptomycin Not assoc w R - Interim
rpsL 781670 c.111G>C synonymous_variant 0.56 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.35 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.56 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.57 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.57 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.57 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.43 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.55 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.5 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.5 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.27 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.46 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.33 streptomycin
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.51 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471997 n.152T>C non_coding_transcript_exon_variant 0.48 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472027 n.182C>T non_coding_transcript_exon_variant 0.47 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.47 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.55 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472057 n.212C>A non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.55 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.56 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.38 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.33 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.3 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.15 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472495 n.650C>T non_coding_transcript_exon_variant 0.15 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472497 n.652G>T non_coding_transcript_exon_variant 0.16 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472580 n.735C>A non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472846 n.1001_1003delCGTinsTAC non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.23 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.23 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.23 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.71 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.2 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.44 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.23 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>G non_coding_transcript_exon_variant 0.15 capreomycin
linezolid
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1473834 n.176_177insT non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473834 n.182G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1473950 n.293G>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756A>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474415 n.759_781delCACACGCGCATACGCGCGTGTGA non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1474709 n.1052_1060delGTGGTGTAAinsAATAAGTTAG non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1474747 n.1090C>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>A non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404_1408delCAAGGinsAAGA non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475201 n.1544G>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1475220 n.1563G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1475422 n.1765A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475481 n.1824C>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475762 n.2105_2108delGCAAinsTT non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.61 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476091 n.2434_2435insC non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.36 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.35 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.35 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.4 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.41 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867delCinsGA non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.48 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.43 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.4 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833547 c.6G>A synonymous_variant 0.39 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.57 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.46 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.55 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.59 pyrazinamide
rpsA 1833616 c.75A>T synonymous_variant 0.58 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.65 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.5 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.76 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.32 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.41 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.74 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.35 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.38 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833700 c.159C>T synonymous_variant 0.37 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.39 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.81 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 0.32 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.81 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.77 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.77 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.31 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
rpsA 1833781 c.240T>C synonymous_variant 0.38 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.66 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.65 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.34 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.34 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.31 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.5 pyrazinamide
rpsA 1833823 c.282G>A synonymous_variant 0.32 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.3 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 0.32 pyrazinamide
rpsA 1833838 c.297G>A synonymous_variant 0.45 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.62 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 0.38 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.64 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.67 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.21 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.65 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.7 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.36 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.38 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.35 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.37 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.39 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.35 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.74 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.31 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.75 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.72 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.69 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.69 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.68 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 0.38 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.28 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.22 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
rpsA 1834228 c.687C>A synonymous_variant 0.45 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.5 pyrazinamide
rpsA 1834234 c.693G>T synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.59 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.65 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.48 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>T synonymous_variant 0.62 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.55 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.72 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834378 c.837T>G synonymous_variant 0.17 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.61 pyrazinamide
rpsA 1834399 p.His286Gln missense_variant 0.21 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.52 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.38 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.54 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834438 c.897C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.63 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.44 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.56 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.41 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834534 c.993C>T synonymous_variant 0.56 pyrazinamide
rpsA 1834540 c.999G>T synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834543 c.1002C>G synonymous_variant 0.64 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.52 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.52 pyrazinamide
rpsA 1834556 p.Ala339Ser missense_variant 0.22 pyrazinamide
rpsA 1834573 c.1032G>A synonymous_variant 0.28 pyrazinamide
rpsA 1834574 p.Met345Leu missense_variant 0.29 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 0.24 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.46 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.24 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.38 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834650 p.Thr370Ser missense_variant 0.21 pyrazinamide
rpsA 1834653 p.Glu371Ala missense_variant 0.21 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.19 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.45 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.27 pyrazinamide
rpsA 1834701 p.Gln387Pro missense_variant 0.21 pyrazinamide
rpsA 1834704 c.1164delC frameshift_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834720 c.1179C>G synonymous_variant 0.26 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.24 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.51 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834759 c.1218A>G synonymous_variant 0.35 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.47 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.46 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.44 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.44 pyrazinamide
rpsA 1834813 c.1272G>T synonymous_variant 0.38 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
Rv1979c 2223051 p.Glu38Asp missense_variant 1.0 bedaquiline Uncertain significance
clofazimine Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517917 c.-198G>C upstream_gene_variant 0.55 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.43 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.38 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.34 isoniazid
kasA 2517968 c.-147T>A upstream_gene_variant 0.29 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.38 isoniazid
kasA 2518738 c.624G>C synonymous_variant 0.3 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.29 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.3 isoniazid
kasA 2518919 p.Gly269Ser missense_variant 1.0 isoniazid
Rv2477c 2783302 c.741A>G synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
thyA 3073868 p.Thr202Ala missense_variant 1.0 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
mtrB 3625705 c.909C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625708 c.906C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625744 c.870G>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.52 rifampicin Uncertain significance
bedaquiline
mtrB 3625761 p.Gln285Glu missense_variant 0.5 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625783 c.-873C>T upstream_gene_variant 0.58 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625813 c.801C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625819 p.Glu265Val missense_variant 0.47 rifampicin Uncertain significance
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626717 c.-104C>T upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrA 3626741 c.609C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626756 c.594C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.39 rifampicin
bedaquiline
rpoA 3877587 c.921A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877614 c.894G>A synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877620 c.888G>A synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877677 p.Ala277Gly missense_variant 0.41 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 0.19 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.26 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.6 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.63 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.37 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.55 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877797 c.711G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877824 c.684G>A synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>A synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>A synonymous_variant 0.56 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877929 p.Ile193Val missense_variant 0.57 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.4 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877977 p.Lys177Asn missense_variant 0.29 rifampicin Uncertain significance
rpoA 3877986 c.522G>T synonymous_variant 0.36 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3878130 c.378C>G synonymous_variant 0.52 rifampicin
rpoA 3878142 p.Gly122Asp missense_variant 0.52 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.63 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.48 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878343 c.165C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3879073 c.-566A>G upstream_gene_variant 0.57 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 0.57 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.5 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.48 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.45 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.48 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.52 rifampicin
clpC1 4038287 c.2418C>T synonymous_variant 1.0 pyrazinamide Not assoc w R
clpC1 4038749 c.1956C>A synonymous_variant 0.6 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.44 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.47 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.57 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.53 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.5 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.95 pyrazinamide
clpC1 4038857 c.1848C>G synonymous_variant 0.53 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038911 c.1794G>C synonymous_variant 0.69 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.67 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.7 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.6 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.58 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039010 c.1695G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039016 c.1689C>G synonymous_variant 0.23 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039031 c.1674T>A synonymous_variant 0.23 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.54 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.68 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.74 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.73 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.72 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.6 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.6 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.67 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.75 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4039265 c.1440C>T synonymous_variant 0.54 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.69 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.6 pyrazinamide Uncertain significance
clpC1 4039418 c.1287C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.74 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.52 pyrazinamide
clpC1 4039528 c.1177C>A synonymous_variant 0.56 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.65 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.58 pyrazinamide
clpC1 4039565 c.1140G>T synonymous_variant 0.61 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.59 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 0.52 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.59 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.64 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.61 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039619 c.1086G>A synonymous_variant 0.5 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.5 pyrazinamide
clpC1 4039646 p.Glu353Asp missense_variant 0.2 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039652 p.Thr351Ser missense_variant 0.19 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039685 c.1020C>G synonymous_variant 0.56 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.63 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.32 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.62 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.63 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.35 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.74 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.34 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4039898 c.807C>G synonymous_variant 0.28 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 0.4 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.63 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.61 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.63 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.52 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.5 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040309 c.396C>T synonymous_variant 0.33 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.27 pyrazinamide
clpC1 4040342 c.363C>A synonymous_variant 0.29 pyrazinamide
clpC1 4040348 c.357G>T synonymous_variant 0.29 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.3 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.3 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.32 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 0.32 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.37 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4040435 c.270G>C synonymous_variant 0.25 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040462 c.243C>G synonymous_variant 0.47 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.62 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>T synonymous_variant 0.36 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.43 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040558 c.147G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.41 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4040579 c.126A>G synonymous_variant 0.35 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.45 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.27 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.36 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.36 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.33 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>C synonymous_variant 0.37 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
panD 4044167 c.115C>T synonymous_variant 0.39 pyrazinamide
panD 4044171 c.111C>T synonymous_variant 0.39 pyrazinamide
panD 4044174 c.108C>T synonymous_variant 0.35 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 0.37 pyrazinamide
panD 4044186 c.94_96delTTGinsCTC synonymous_variant 0.39 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.37 pyrazinamide
panD 4044194 p.Ala30Pro missense_variant 0.35 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.35 pyrazinamide
panD 4044219 c.63C>T synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
panD 4044232 p.Cys17His missense_variant 0.38 pyrazinamide
panD 4044234 c.48C>G synonymous_variant 0.33 pyrazinamide
glpK 4138601 c.1155G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138607 c.1149G>T synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138610 c.1146C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138616 c.1140G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>A synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>A synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138643 c.1113A>G synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138664 c.1092G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138694 p.Pro354Glu missense_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138706 c.1050C>G synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138712 p.Ala348Asp missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 p.Ala344Ser missense_variant 0.29 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138751 c.1005T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138772 c.984G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
gid 4408156 p.Leu16Arg missense_variant 1.0 streptomycin Not assoc w R