Run ID: ERR9786569
Sample name:
Date: 2024-10-03T20:23:07.775051
Number of reads: 2384827
Percentage reads mapped: 73.54
Median coverage: 105.0
Strain: lineage4.8
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.2.BCG | M.bovis | None | 0.12 |
lineage4 | Euro-American | None | 0.94 |
lineage4.8 | Euro-American (mainly T) | RD219 | 0.97 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Leu359Ile | Uncertain significance | Mutation from literature | ||
p.Tyr384Asn | Mutation from literature | |||
p.Ala388Gly | Mutation from literature | |||
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance | Mutation from literature |
embB | 4247448 | p.His312Arg | missense_variant | 0.26 | ethambutol | Mutation from literature | |
embB | 4247588 | p.Leu359Ile | missense_variant | 0.26 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4247663 | p.Tyr384Asn | missense_variant | 0.23 | ethambutol | Mutation from literature | |
embB | 4247676 | p.Ala388Gly | missense_variant | 0.25 | ethambutol | Mutation from literature | |
embB | 4247708 | p.Asn399Asp | missense_variant | 0.25 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 705 | c.705A>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 720 | c.720G>A | synonymous_variant | 0.21 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.18 | isoniazid | Not assoc w R - Interim |
dnaA | 882 | c.882C>T | synonymous_variant | 0.16 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 945 | c.945G>A | synonymous_variant | 0.18 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.17 | isoniazid | |
dnaA | 975 | c.975G>T | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1041 | c.1041G>A | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1137 | c.1137C>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1143 | c.1143G>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1188 | c.1188G>A | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1197 | c.1197T>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1218 | c.1218C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.22 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
gyrB | 6238 | c.999G>A | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6490 | c.-812T>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6499 | c.-803A>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6502 | c.-800T>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6508 | c.-794A>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6523 | c.-779G>T | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6526 | c.-776T>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6535 | c.-767C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6541 | c.1302C>T | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6550 | c.1311A>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6565 | c.-737G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6571 | c.-731T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6577 | c.1338T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6808 | c.1569C>T | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6898 | c.-404G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6901 | c.-401G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6916 | c.-386G>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | p.Ser629Thr | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7433 | c.132G>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>A | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7562 | c.261C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 0.31 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7673 | c.372G>A | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382_384delAGGinsCGC | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7721 | c.420G>A | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7725 | c.424C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7739 | c.438C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7772 | c.471C>T | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7796 | c.495G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7823 | c.522G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8237 | c.936A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8276 | c.975G>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.3 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8337 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8367 | c.1066C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | p.Tyr364His | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8400 | p.Asp367Asn | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8417 | c.1116C>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8465 | c.1164C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8708 | c.1407G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8750 | c.1449C>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Ser | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8807 | c.1506C>T | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8816 | c.1515C>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.24 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9023 | c.1722A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9029 | c.1728T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9056 | c.1755C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9065 | c.1764C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9152 | c.1851C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.2 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
Rv0010c | 13642 | c.-84A>G | upstream_gene_variant | 0.99 | isoniazid | Uncertain significance |
fgd1 | 490782 | c.-1G>C | upstream_gene_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490854 | c.72C>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490935 | c.153C>G | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490962 | c.180T>G | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490977 | c.195C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490983 | c.201G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490984 | p.Leu68Ile | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490987 | p.Leu69Thr | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491001 | c.219G>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491077 | p.Asn99Gly | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491082 | c.300T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491083 | p.Val101Ile | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491302 | p.Ile174Val | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491307 | c.525C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491313 | c.531C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491325 | c.543G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
mshA | 575576 | c.229C>T | synonymous_variant | 0.18 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575581 | c.234C>T | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 575587 | c.240C>G | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 575590 | c.243T>C | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 575623 | c.276C>G | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575629 | c.282A>G | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575632 | c.285G>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575635 | c.288A>C | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575638 | c.291T>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575641 | c.294A>G | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575647 | c.300G>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575649 | p.Val101Ala | missense_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
mshA | 575662 | c.315C>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
mshA | 575665 | c.318G>A | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
mshA | 575674 | c.327G>C | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575701 | c.354G>A | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575704 | c.357T>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575755 | c.408G>A | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575756 | c.409C>T | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619528 | c.-363C>G | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619531 | c.-360T>C | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619609 | c.-282G>C | upstream_gene_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619699 | c.-192G>C | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619705 | c.-186G>C | upstream_gene_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 656265 | c.1204_1205delAC | frameshift_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656402 | p.Ala357Thr | missense_variant | 0.19 | ethionamide | |
Rv0565c | 656412 | c.1059T>G | synonymous_variant | 0.2 | ethionamide | |
Rv0565c | 656418 | c.1053A>G | synonymous_variant | 0.2 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.19 | ethionamide | |
hadA | 732337 | c.408G>A | synonymous_variant | 0.17 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.31 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.33 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.32 | isoniazid | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.17 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.22 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.23 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.23 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734601 | c.348C>G | synonymous_variant | 0.24 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.22 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734637 | c.384G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 0.21 | rifampicin | |
nusG | 734658 | c.405A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
nusG | 734661 | c.408A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
nusG | 734664 | c.411T>G | synonymous_variant | 0.19 | rifampicin | |
nusG | 734680 | p.Ala143Thr | missense_variant | 0.18 | rifampicin | |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760319 | c.513C>T | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.37 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.36 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.39 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.35 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.36 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.19 | rifampicin | |
rpoB | 760776 | p.Ser324Thr | missense_variant | 0.16 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761123 | c.1317G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.3 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.31 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761439 | p.Asp545Lys | missense_variant | 0.23 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.22 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.22 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761720 | c.1914_1916delCGAinsGG | frameshift_variant&synonymous_variant | 0.25 | rifampicin | |
rpoB | 761727 | p.Ser641Gly | missense_variant | 0.26 | rifampicin | |
rpoB | 761728 | c.1923dupC | frameshift_variant | 0.25 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.26 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.27 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.28 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.28 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.29 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.3 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.3 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.3 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.27 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.28 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.37 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.2 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.3 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.26 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.23 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.23 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763942 | c.573C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763948 | c.579G>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763949 | c.580C>A | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763954 | c.585C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763963 | c.594C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.21 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.25 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.22 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.26 | rifampicin | |
rpoC | 764107 | c.738C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.26 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.28 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | p.Ser562Thr | missense_variant | 0.18 | rifampicin | |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.24 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.35 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.34 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.4 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.33 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.33 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 766174 | p.Asn935Lys | missense_variant | 0.25 | rifampicin | |
rpoC | 766178 | p.Ile937Val | missense_variant | 0.23 | rifampicin | |
rpoC | 766185 | p.Glu939Ala | missense_variant | 0.21 | rifampicin | |
rpoC | 766189 | c.2820T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766192 | c.2823T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 766193 | p.Gln942Glu | missense_variant | 0.2 | rifampicin | |
rpoC | 766204 | c.2835C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766207 | c.2838T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766216 | c.2847T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 766222 | c.2853T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 766231 | c.2862T>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766234 | c.2865T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766237 | c.2868T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 766240 | c.2871T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766243 | c.2874C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766258 | c.2889T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.26 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.28 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.44 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.38 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.32 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.33 | rifampicin | |
rpoC | 766625 | c.3256C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.25 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 766882 | c.3513C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.33 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.35 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.33 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 767111 | c.3742C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.36 | rifampicin | |
rpoC | 767158 | c.3789T>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.25 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.2 | rifampicin | |
rpoC | 767275 | c.3906T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 0.2 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 777292 | p.Ala397Ser | missense_variant | 1.0 | bedaquiline | Uncertain significance |
clofazimine | Uncertain significance | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.23 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.39 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.39 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.39 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.39 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.39 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.4 | streptomycin | Uncertain significance |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.23 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.23 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.21 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.2 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.2 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.19 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.19 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.2 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.21 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.19 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.19 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.23 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.27 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.3 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.27 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.27 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.27 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.27 | linezolid | |
fbiC | 1303497 | c.567G>A | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303501 | c.571C>T | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303548 | c.618G>A | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303641 | c.711C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303650 | c.720G>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303654 | c.724C>T | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303661 | p.Val244Ala | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303663 | c.733C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303671 | c.741C>T | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303681 | c.751T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303932 | c.1002G>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304085 | c.1155C>T | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304106 | c.1176G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304535 | c.1605G>A | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304545 | p.Val539Ile | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304553 | c.1623C>T | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304671 | p.Val581Thr | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.28 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304862 | c.1932G>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305063 | c.2133G>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.27 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.27 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1673660 | c.-542C>A | upstream_gene_variant | 0.15 | isoniazid | |
ethionamide | ||||||
inhA | 1673685 | c.-517C>T | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673710 | c.-492C>A | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673733 | c.-469G>C | upstream_gene_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1673749 | c.-453_-452delAAinsCG | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1673758 | c.-444A>G | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1673797 | c.-405_-403delGCTinsACC | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673802 | c.-400A>G | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1673805 | c.-397G>C | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673808 | c.-394A>C | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673809 | c.-393T>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673823 | c.-378_-375delCGCA | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673829 | c.-373C>A | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673832 | c.-370_-369insGCGG | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673841 | c.-361A>C | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673844 | c.-358G>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673847 | c.-355A>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673849 | c.-353T>A | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673853 | c.-349A>C | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673856 | c.-346T>C | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673890 | c.-312G>T | upstream_gene_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1673901 | c.-301A>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673905 | c.-297T>G | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1673916 | c.-286A>C | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673941 | c.-261_-259delGCCinsTCT | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674504 | c.303C>G | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674741 | c.540C>T | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674750 | c.549T>C | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674753 | c.552G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.28 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674789 | c.588G>C | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674822 | c.621C>G | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674864 | c.663C>T | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674888 | c.687C>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.23 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.24 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834333 | c.792C>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834606 | c.1065C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.32 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.28 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.26 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.21 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853423 | c.-183C>T | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.19 | linezolid | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1918036 | p.Arg33Ser | missense_variant | 0.17 | capreomycin | |
tlyA | 1918048 | p.Leu37Met | missense_variant | 0.17 | capreomycin | |
tlyA | 1918082 | p.Asp48Val | missense_variant | 0.17 | capreomycin | |
bacA | 2064933 | c.-205A>G | upstream_gene_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064936 | c.-208C>G | upstream_gene_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064942 | c.-214G>A | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.35 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.35 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.35 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.36 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.36 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
katG | 2154992 | p.Ser374Pro | missense_variant | 1.0 | isoniazid | |
PPE35 | 2168149 | p.Pro822Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.21 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.2 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2518474 | c.360G>A | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518483 | c.369C>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.26 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.3 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.32 | isoniazid | |
kasA | 2518624 | c.510C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518639 | c.525G>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518693 | c.579C>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518819 | c.705C>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.23 | isoniazid | |
kasA | 2518921 | c.807T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518927 | c.813C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518939 | c.825T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518942 | c.828T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518951 | c.837G>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518954 | c.840C>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518963 | c.849T>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518969 | c.855T>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518975 | c.861C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518979 | c.865A>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518990 | c.876T>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518993 | c.879C>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518999 | c.885G>A | synonymous_variant | 0.25 | isoniazid | |
kasA | 2519008 | c.894C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519017 | c.903G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519020 | c.906G>C | synonymous_variant | 0.26 | isoniazid | |
kasA | 2519021 | p.Ala303Lys | missense_variant | 0.26 | isoniazid | |
kasA | 2519027 | p.Ile305Val | missense_variant | 0.25 | isoniazid | |
kasA | 2519050 | c.936C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519053 | c.939G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519062 | c.948T>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.32 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519108 | p.Asp332Gln | missense_variant | 0.3 | isoniazid | |
kasA | 2519116 | c.1002C>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.24 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.26 | isoniazid | |
Rv2477c | 2782714 | c.1329A>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782720 | c.1323T>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782741 | c.1302G>A | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782802 | p.Gln414Leu | missense_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782816 | c.1227T>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782822 | c.1221G>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782828 | c.1215T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782841 | p.Thr401Asn | missense_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782847 | p.Arg399Lys | missense_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782852 | c.1191T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.33 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.34 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.35 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.36 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.36 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.41 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.4 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783179 | c.864G>C | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783401 | c.642C>T | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783425 | p.Pro206Ala | missense_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | ||||||
Rv2477c | 2783428 | c.615C>T | synonymous_variant | 0.21 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783431 | c.610_612delAGCinsTCG | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783437 | c.606G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783446 | c.597A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783497 | c.544_546delTTGinsCTC | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.22 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783521 | c.522G>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.17 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin |