TB-Profiler result

Run: SRR11342696
Summary

Run ID: SRR11342696

Sample name:

Date: 2024-04-15T19:34:27.407176

Number of reads: 3114114

Percentage reads mapped: 85.9

Median coverage: 76.0

Strain: lineage4.4.1.1.1

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.4.1.1.1 Euro-American None 1.0
lineage4.4.1 Euro-American (S-type) None 0.91
lineage4 Euro-American None 1.0
lineage4.4.1.1 Euro-American None 1.0
lineage4.4 Euro-American None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1321_1323delTCGinsGC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.His445Arg Assoc w R
p.Ser450Asn Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.Leu464Met Mutation from literature
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.Gly406Ala Assoc w R
pyrazinamide pncA p.Phe58Ser Assoc w R - Interim
streptomycin rrs n.888G>A Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761127 c.1321_1323delTCGinsGC frameshift_variant&missense_variant 0.89 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761140 p.His445Arg missense_variant 0.17 rifampicin Assoc w R
rpoB 761154 p.Ser450Asn missense_variant 0.65 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761196 p.Leu464Met missense_variant 0.83 rifampicin Mutation from literature
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance Mutation from literature
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
pncA 2289069 p.Phe58Ser missense_variant 1.0 pyrazinamide Assoc w R - Interim
embB 4247730 p.Gly406Ala missense_variant 1.0 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5239 c.-1C>G upstream_gene_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
mshA 575719 c.372C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.19 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.46 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761031 c.1225_1227delCAGinsAC frameshift_variant&missense_variant 0.46 rifampicin
rpoB 761036 c.1230G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231_1233delTTGinsCC frameshift_variant&missense_variant 0.62 rifampicin
rpoB 761051 c.1245G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761058 p.Val418Thr missense_variant 0.6 rifampicin
rpoB 761084 c.1278C>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.88 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 0.84 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.17 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.87 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761159 c.1353G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761186 p.Glu460Asp missense_variant 0.21 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 0.19 rifampicin
rpoB 761193 p.Gly463Ser missense_variant 0.61 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.19 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.17 rifampicin
rpoB 761207 c.1401C>A synonymous_variant 0.2 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.81 rifampicin
rpoB 761217 c.1411_1413delCCGinsAC frameshift_variant&missense_variant 0.61 rifampicin
rpoB 761231 c.1425C>G synonymous_variant 0.61 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761243 c.1437G>C synonymous_variant 0.51 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761250 p.Thr482Ser missense_variant 0.67 rifampicin
rpoB 761255 c.1449T>C synonymous_variant 0.42 rifampicin
rpoB 761258 c.1452G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761276 c.1470G>C synonymous_variant 0.44 rifampicin
rpoB 761289 p.Ser495Ala missense_variant 0.17 rifampicin
rpoB 761507 c.1701G>C synonymous_variant 0.14 rifampicin
rpoB 761511 p.Glu569Gln missense_variant 0.19 rifampicin
rpoB 761520 p.Tyr572Leu missense_variant 0.27 rifampicin
rpoB 761534 c.1728G>C synonymous_variant 0.35 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761557 p.Ala584Gly missense_variant 0.38 rifampicin Uncertain significance
rpoB 761562 c.1756_1758delGCGinsTC frameshift_variant&missense_variant 0.37 rifampicin
rpoB 761565 c.1759_1761delATGinsCC frameshift_variant&missense_variant 0.37 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.45 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.51 rifampicin
rpoB 761642 c.1836G>C synonymous_variant 0.49 rifampicin
rpoB 761643 p.Val613Ile missense_variant 0.49 rifampicin Uncertain significance
rpoB 761648 c.1842T>C synonymous_variant 0.49 rifampicin
rpoB 761649 p.Ser615Pro missense_variant 0.49 rifampicin
rpoB 761654 p.Glu616Asp missense_variant 0.5 rifampicin
rpoB 761672 c.1866C>G synonymous_variant 0.44 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.45 rifampicin
rpoB 761683 p.Leu626Arg missense_variant 0.43 rifampicin
rpoB 761688 c.1882_1884delGCGinsAC frameshift_variant&missense_variant 0.33 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.32 rifampicin
rpoB 761694 p.Ile630Val missense_variant 0.33 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.3 rifampicin
rpoB 761712 p.Val636Leu missense_variant 0.24 rifampicin
rpoB 761945 c.2139G>C synonymous_variant 0.15 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 0.18 rifampicin
rpoB 761955 p.Ile717Phe missense_variant 0.17 rifampicin
rpoB 761974 p.His723Leu missense_variant 0.2 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762003 p.Asn733His missense_variant 0.15 rifampicin
rpoB 762024 p.Val740Met missense_variant 0.3 rifampicin
rpoB 762051 c.2245_2247delCATinsTC frameshift_variant&missense_variant 0.16 rifampicin
rpoB 762057 p.Ile751Val missense_variant 0.38 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.19 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762085 p.Ala760Asp missense_variant 0.2 rifampicin
rpoB 762089 c.2283G>A synonymous_variant 0.21 rifampicin
rpoB 762110 c.2304G>C synonymous_variant 0.38 rifampicin
rpoB 762114 p.Ile770Val missense_variant 0.38 rifampicin Uncertain significance
rpoB 762117 c.2311_2312delTCinsAG synonymous_variant 0.17 rifampicin
rpoB 762122 p.Asp772Glu missense_variant 0.36 rifampicin
rpoB 762125 c.2319G>A synonymous_variant 0.19 rifampicin
rpoB 762126 p.Val774Ser missense_variant 0.23 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.17 rifampicin
rpoB 762134 c.2328C>T synonymous_variant 0.17 rifampicin
rpoB 762135 p.Asp777Asn missense_variant 0.18 rifampicin Uncertain significance
rpoB 762140 c.2334G>C synonymous_variant 0.19 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.39 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 0.4 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762177 p.Arg791Thr missense_variant 0.19 rifampicin
rpoB 762180 p.Asp792Ser missense_variant 0.22 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762197 c.2391C>G synonymous_variant 0.21 rifampicin
rpoB 762206 c.2400C>G synonymous_variant 0.21 rifampicin
rpoB 762212 c.2406G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.19 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 0.26 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.18 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 762842 c.-528G>C upstream_gene_variant 0.27 rifampicin
rpoC 762854 c.-516G>C upstream_gene_variant 0.26 rifampicin
rpoB 762855 p.Val1017Ile missense_variant 0.68 rifampicin
rpoB 762858 p.Thr1018Ser missense_variant 0.66 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 0.72 rifampicin
rpoB 762871 p.Met1022Thr missense_variant 0.38 rifampicin
rpoB 762878 p.Ile1024Met missense_variant 0.36 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.73 rifampicin
rpoB 762887 c.3081G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 762896 c.-474G>C upstream_gene_variant 0.3 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.72 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762938 c.-432G>C upstream_gene_variant 0.29 rifampicin
rpoC 762944 c.-426C>T upstream_gene_variant 0.19 rifampicin
rpoC 762947 c.-423C>G upstream_gene_variant 0.52 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.79 rifampicin
rpoC 762980 c.-390T>C upstream_gene_variant 0.55 rifampicin
rpoC 762983 c.-387C>T upstream_gene_variant 0.21 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.76 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.71 rifampicin
rpoB 763014 p.Met1070Leu missense_variant 0.54 rifampicin
rpoB 763017 c.3211_3213delCAGinsGA frameshift_variant&missense_variant 0.7 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.17 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.7 rifampicin Not assoc w R
rpoB 763038 p.Thr1078Ala missense_variant 0.67 rifampicin
rpoC 763043 c.-327G>C upstream_gene_variant 0.66 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 763077 p.Val1091Thr missense_variant 0.57 rifampicin
rpoC 763085 c.-285C>A upstream_gene_variant 0.16 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.47 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 763119 p.Asn1105Asp missense_variant 0.37 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.28 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.2 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.34 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.38 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.57 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.56 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.57 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.51 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.58 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 0.66 rifampicin
rpoC 763585 c.216C>G synonymous_variant 0.57 rifampicin
rpoC 763589 p.Ile74Val missense_variant 0.55 rifampicin
rpoC 763606 c.237C>A synonymous_variant 0.63 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.64 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.66 rifampicin Uncertain significance
rpoC 763636 c.267T>C synonymous_variant 0.54 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763647 p.Gly93Ala missense_variant 0.55 rifampicin
rpoC 763655 p.Glu96Lys missense_variant 0.6 rifampicin
rpoC 763660 c.291T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.56 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.48 rifampicin
rpoC 763724 p.Asp119Asn missense_variant 0.48 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.42 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.44 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.47 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.46 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763772 p.Val135Met missense_variant 0.27 rifampicin
rpoC 764359 c.990C>G synonymous_variant 0.16 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.2 rifampicin
rpoC 764404 c.1035C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.22 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.22 rifampicin
rpoC 764424 p.Asn352Thr missense_variant 0.24 rifampicin
rpoC 764428 c.1059G>A synonymous_variant 0.24 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCC frameshift_variant&missense_variant 0.25 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.3 rifampicin
rpoC 764446 p.Asp359Glu missense_variant 0.31 rifampicin
rpoC 764455 c.1086G>C synonymous_variant 0.36 rifampicin
rpoC 764458 c.1089G>T synonymous_variant 0.27 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.7 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.7 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764498 p.Ser377Ala missense_variant 0.26 rifampicin
rpoC 764503 c.1134G>T synonymous_variant 0.63 rifampicin
rpoC 764509 c.1140G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764512 c.1143G>C synonymous_variant 0.46 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.21 rifampicin
rpoC 764530 c.1161C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.21 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 0.51 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764543 c.1174_1176delACCinsGG frameshift_variant&missense_variant 0.44 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.49 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764549 p.Pro394Val missense_variant 0.35 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.44 rifampicin
rpoC 764573 c.1204_1206delCTTinsAC frameshift_variant&missense_variant 0.43 rifampicin
rpoC 764578 c.1209C>G synonymous_variant 0.43 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.87 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.88 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.43 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>T synonymous_variant 0.43 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764620 c.1251G>C synonymous_variant 0.26 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.31 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.42 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.28 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.43 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>C synonymous_variant 0.3 rifampicin
rpoC 764677 c.1308C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764678 p.Lys437Gln missense_variant 0.42 rifampicin
rpoC 764683 c.1314G>C synonymous_variant 0.29 rifampicin
rpoC 764703 p.Lys445Ser missense_variant 0.21 rifampicin
rpoC 764706 p.Leu446Gln missense_variant 0.64 rifampicin Uncertain significance
rpoC 764713 c.1344G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764731 c.1362G>C synonymous_variant 0.53 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.5 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 0.29 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.16 rifampicin
rpoC 764752 c.1383G>T synonymous_variant 0.26 rifampicin
rpoC 764755 p.Asp462Glu missense_variant 0.28 rifampicin
rpoC 764756 p.Leu463Lys missense_variant 0.21 rifampicin
rpoC 764762 c.1393_1395delCATinsTC frameshift_variant&missense_variant 0.23 rifampicin
rpoC 764774 p.Ile469Val missense_variant 0.23 rifampicin
rpoC 764780 p.Ser471Ala missense_variant 0.24 rifampicin
rpoC 764793 p.Met475Lys missense_variant 0.23 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.24 rifampicin
rpoC 764813 c.1444_1446delCAAinsGG frameshift_variant&missense_variant 0.21 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764944 p.His525Gln missense_variant 1.0 rifampicin Uncertain significance
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rplC 800511 c.-298A>C upstream_gene_variant 0.22 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.23 linezolid
rplC 800520 c.-289G>T upstream_gene_variant 0.23 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.21 linezolid
rplC 800536 c.-273C>T upstream_gene_variant 0.21 linezolid
rplC 800544 c.-265_-263delGCTinsTC upstream_gene_variant 0.22 linezolid
rplC 800566 c.-242_-240delAAC upstream_gene_variant 0.19 linezolid
rplC 800576 c.-233_-229delCCGCAinsGACCCGCG upstream_gene_variant 0.18 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 0.17 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.17 linezolid
rplC 800588 c.-221C>G upstream_gene_variant 0.17 linezolid
rplC 800590 c.-219_-218delGCinsCG upstream_gene_variant 0.17 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.16 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.16 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.16 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.15 linezolid
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.51 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441_442insT non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472292 n.447A>T non_coding_transcript_exon_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_454insCCTG non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472302 n.457_466delGGGTTCTCTCinsCTTGTGGGT non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472319 n.474C>G non_coding_transcript_exon_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472326 n.481T>G non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472329 n.484A>T non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472425 n.580T>C non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472445 n.601dupT non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472449 n.604_606delCACinsTCT non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472484 n.639A>C non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472486 n.641A>G non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.34 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472673 n.828_837delTTTCCTTCCTinsGGCCACCCG non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472673 n.828_838delTTTCCTTCCTTinsGGGCCTTTTCC non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.51 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472837 n.992_998delCACAGGAinsTGCCGGT non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472846 n.1002delG non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472846 n.1001_1003delCGTinsGCA non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472850 n.1005_1006insGC non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472856 n.1012_1021delAGGCGTTCCCinsGTGGTGGCAT non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472856 n.1011_1019delTAGGCGTTCinsCGGGGTTTCCT non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472870 n.1025_1030delTGGCCTinsGTTGGTC non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472878 n.1033G>T non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472879 n.1034T>C non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.47 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.42 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.92 streptomycin Not assoc w R
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473284 n.1439A>T non_coding_transcript_exon_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473287 n.1442_1449delCCTCGGGAinsG non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.36 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474288 n.631_649delCCTTTTCCTCTCCGGAGGAinsT non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474315 n.658A>G non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474414 n.757_778delCCCACACGCGCATACGCGCGTGinsT non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474483 n.826C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474551 n.894G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016_1019delTACTinsCACA non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1052_1060delGTGGTGTAAinsATTAGGTGT non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096_1097delACinsG non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096_1097delACinsG non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.51 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474946 n.1289C>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1475016 n.1359C>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475018 n.1361G>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1475026 n.1369G>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475076 n.1419_1422delCCTTinsGCCCTA non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.27 capreomycin
linezolid Uncertain significance
rrl 1475602 n.1945_1953delGGAATATCGinsTGATCCC non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475616 n.1959A>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475620 n.1963T>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475631 n.1975_1982delCGGGATCC non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475650 n.1993A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475760 n.2103_2110delCCGCAAGGinsATTCTTTGTGGGT non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475998 n.2341C>G non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid Uncertain significance
rrl 1475999 n.2342G>A non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476059 n.2402G>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>G non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.24 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.42 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid Uncertain significance
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476293 n.2636_2637delCAinsTG non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476293 n.2637A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.66 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.71 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833641 c.100_102delAACinsGT frameshift_variant&missense_variant 0.22 pyrazinamide Uncertain significance
rpsA 1833646 c.105T>C synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
rpsA 1833652 c.111C>T synonymous_variant 0.31 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.36 pyrazinamide
rpsA 1833667 c.126C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833668 p.Ile43Val missense_variant 0.39 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.38 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.38 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.35 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.51 pyrazinamide
rpsA 1833732 p.Pro64Leu missense_variant 0.54 pyrazinamide
rpsA 1833736 c.195C>T synonymous_variant 0.53 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.54 pyrazinamide
rpsA 1833757 c.216C>T synonymous_variant 0.35 pyrazinamide
rpsA 1833770 p.Asn77Asp missense_variant 0.54 pyrazinamide
rpsA 1833776 p.Val79Ile missense_variant 0.53 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.52 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.46 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.47 pyrazinamide Uncertain significance
rpsA 1833808 c.267G>C synonymous_variant 0.43 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.43 pyrazinamide
rpsA 1833814 c.273C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833815 p.Thr92Gln missense_variant 0.42 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.42 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.42 pyrazinamide
rpsA 1833835 c.294C>G synonymous_variant 0.42 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.42 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.42 pyrazinamide
rpsA 1833842 p.Ile101Leu missense_variant 0.43 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.43 pyrazinamide
rpsA 1833848 c.307_308delTCinsAG synonymous_variant 0.42 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.49 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.52 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.58 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.59 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.59 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.59 pyrazinamide
rpsA 1833926 c.385_387delACGinsTC frameshift_variant&missense_variant 0.55 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.55 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.49 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.6 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.6 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.61 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.58 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 0.53 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.51 pyrazinamide
rpsA 1834034 c.493_495delATCinsGG frameshift_variant&missense_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834040 p.Lys167Arg missense_variant 0.59 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 0.51 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.55 pyrazinamide
rpsA 1834063 c.522C>T synonymous_variant 0.43 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.55 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.38 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834140 p.Ser200Thr missense_variant 0.19 pyrazinamide
rpsA 1834144 p.Glu201Asp missense_variant 0.14 pyrazinamide
rpsA 1834183 c.642T>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>T synonymous_variant 0.17 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.34 pyrazinamide
rpsA 1834228 c.687C>T synonymous_variant 0.35 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.39 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.42 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.51 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.54 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.48 pyrazinamide Uncertain significance
rpsA 1834312 c.771G>A synonymous_variant 0.38 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.47 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.38 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.32 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834427 c.886_888delATCinsGT frameshift_variant&missense_variant 0.39 pyrazinamide Uncertain significance
rpsA 1834435 c.894G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCC frameshift_variant&missense_variant 0.38 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834459 c.918G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.16 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.22 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.16 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.37 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.29 pyrazinamide
rpsA 1834522 c.981C>G synonymous_variant 0.26 pyrazinamide
rpsA 1834523 p.Glu328Gln missense_variant 0.31 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834546 p.Asp335Glu missense_variant 0.28 pyrazinamide
rpsA 1834552 c.1013_1015delTTG disruptive_inframe_deletion 0.24 pyrazinamide
rpsA 1834558 c.1017_1018insAAG conservative_inframe_insertion 0.25 pyrazinamide
rpsA 1834570 p.Asp343Glu missense_variant 0.25 pyrazinamide
rpsA 1834572 p.Ala344Val missense_variant 0.26 pyrazinamide
rpsA 1834574 c.1033_1035delATGinsTC frameshift_variant&missense_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.16 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.19 pyrazinamide
tsnR 1853674 c.69G>A synonymous_variant 1.0 linezolid Not assoc w R - Interim
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
ndh 2102990 p.Val18Ala missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Not assoc w R
PPE35 2169840 p.Gly258Asp missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
Rv3083 3448608 c.105G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv3236c 3612665 p.Val151Ala missense_variant 1.0 pyrazinamide Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
clpC1 4039694 c.1011G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.21 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.22 pyrazinamide
clpC1 4039754 c.951G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.22 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.22 pyrazinamide
clpC1 4039773 p.Lys311Met missense_variant 0.21 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.21 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.19 pyrazinamide
clpC1 4039838 c.865_867delCTGinsAC frameshift_variant&missense_variant 0.21 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.26 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.21 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.15 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040045 c.660C>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040066 c.639G>C synonymous_variant 0.18 pyrazinamide
clpC1 4040069 c.636G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040096 c.609G>C synonymous_variant 0.15 pyrazinamide
clpC1 4040125 p.Glu194Lys missense_variant 0.16 pyrazinamide
embC 4238963 c.-900C>T upstream_gene_variant 1.0 ethambutol Not assoc w R
embC 4239274 c.-589C>G upstream_gene_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin