TB-Profiler result

Run: ERR3290633
Summary

Run ID: ERR3290633

Sample name:

Date: 2024-04-16T02:19:07.139685

Number of reads: 459225

Percentage reads mapped: 25.26

Median coverage: 11.0

Strain: lineage4.2;lineage4.6.3;lineage4.9.1

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.06
lineage4.9.1 Euro-American (H37Rv-like) None 0.06
lineage4.2 Euro-American None 0.06
lineage4.6.3 Euro-American None 0.07
lineage3.1.2.2 East-African-Indian RD750 0.08
lineage4 Euro-American None 0.89
lineage4.9 Euro-American (H37Rv-like) None 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.763_765delACAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1051_1053delATGinsTT Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491545 c.763_765delACAinsTG frameshift_variant&stop_gained 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
fbiB 3642585 c.1051_1053delATGinsTT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1195 c.1195_1197delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1200 c.1200C>T synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
gyrB 6202 c.963C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6214 c.975G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6217 c.978G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6283 c.1044C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6803 c.-499C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6866 c.-436C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7024 c.-278G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7027 c.-275G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Ala missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7430 c.129G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7460 c.159C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7463 c.162G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7475 c.174A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7493 c.192C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7502 c.201C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7614 c.313C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7806 c.505_507delCGGinsAA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7821 c.520C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7829 c.528C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7847 c.546G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8057 c.756A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8102 c.801C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8165 c.864C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8477 c.1176C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8481 c.1180C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8525 c.1224C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8534 c.1233G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 c.1234_1236delGAGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8570 c.1269G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8618 c.1317G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8637 c.1336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8774 c.1473C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8837 c.1536C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8846 c.1545C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8924 c.1623C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8933 c.1632G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8963 c.1662C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9065 c.1764C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491100 c.318C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491109 c.327G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491127 c.345C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491144 p.Ala121Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491176 c.394C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491206 c.424C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491268 c.486C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491277 c.495G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491583 c.801G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491598 c.816C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491631 c.849C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491643 c.861G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491688 c.906A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491697 c.915G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574766 c.-582T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575828 p.Val161Ile missense_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575924 p.Gly193Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575935 c.588G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575947 c.600G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575956 c.609G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575983 c.636G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575984 c.637_639delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576001 p.Asp218Glu missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576004 c.657T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576010 c.663C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576011 p.Arg222Gln missense_variant 1.0 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 1.0 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619527 c.-364C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619532 c.-359C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619537 c.-354A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619560 c.-331_-330delCGinsGC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619564 c.-327C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619571 c.-320_-318delGTGinsAC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619603 c.-288C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619606 c.-285C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619615 c.-276C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620205 c.315G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620262 c.372C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620268 c.378G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 c.379_381delGTCinsAA frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620280 c.390C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620329 c.439_441delATCinsGG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620679 c.789C>G synonymous_variant 1.0 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620688 c.798G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620691 c.801G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657219 p.Ala84Glu missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
Rv0565c 657246 c.225C>G synonymous_variant 1.0 ethionamide
Rv0565c 657258 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734463 c.210G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734508 c.255C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734544 c.291C>T synonymous_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>T synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 1.0 rifampicin
nusG 734763 c.510C>G synonymous_variant 1.0 rifampicin
nusG 734766 c.513C>T synonymous_variant 1.0 rifampicin
nusG 734771 p.Ala173Val missense_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734844 c.591G>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760271 c.465C>G synonymous_variant 1.0 rifampicin
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760313 c.507G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>C synonymous_variant 1.0 rifampicin
rpoB 760343 c.537G>C synonymous_variant 1.0 rifampicin
rpoB 760358 c.552C>G synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760367 c.561G>A synonymous_variant 1.0 rifampicin
rpoB 760373 c.567C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760400 c.594G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760422 c.616_618delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760514 c.708C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 1.0 rifampicin
rpoB 760536 p.Glu244Gln missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760571 c.765G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760643 c.837G>A synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760910 c.1104C>A synonymous_variant 1.0 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>T synonymous_variant 1.0 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761160 c.1354C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761201 c.1395G>A synonymous_variant 1.0 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761369 c.1563G>A synonymous_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 1.0 rifampicin
rpoB 761384 c.1578C>G synonymous_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761434 p.Asp543Ala missense_variant 1.0 rifampicin
rpoB 761437 p.Ala544Glu missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761451 p.Val549Leu missense_variant 1.0 rifampicin
rpoB 761462 c.1656C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761466 c.1660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761477 c.1671C>G synonymous_variant 1.0 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761651 c.1845C>T synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>A synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 1.0 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 1.0 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 1.0 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761729 c.1923C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.94 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761831 c.2025C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 1.0 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762023 c.2217C>T synonymous_variant 1.0 rifampicin
rpoB 762027 c.2221_2223delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762032 c.2226C>G synonymous_variant 1.0 rifampicin
rpoB 762035 c.2229G>C synonymous_variant 1.0 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762041 c.2235C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>T synonymous_variant 1.0 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762128 c.2322G>C synonymous_variant 1.0 rifampicin
rpoB 762138 c.2332C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>A synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762390 c.-980C>T upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoB 762631 p.Ala942Val missense_variant 1.0 rifampicin
rpoB 762638 p.Lys944Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 762710 c.-660G>C upstream_gene_variant 1.0 rifampicin
rpoB 762725 c.2919C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762749 c.-621C>G upstream_gene_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762765 c.-605C>T upstream_gene_variant 1.0 rifampicin
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762894 c.3088C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762911 c.-459C>T upstream_gene_variant 1.0 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 1.0 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.93 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763220 c.-150G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763447 c.78C>T synonymous_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>T synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763666 c.297G>A synonymous_variant 0.95 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.94 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763721 c.352C>T synonymous_variant 0.94 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.95 rifampicin
rpoC 763747 c.378G>A synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763786 c.417C>G synonymous_variant 1.0 rifampicin
rpoC 763801 c.432C>T synonymous_variant 0.94 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Leu missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763885 c.516C>G synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763930 c.561G>A synonymous_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.92 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.92 rifampicin
rpoC 763949 p.Arg194Lys missense_variant 0.92 rifampicin
rpoC 763960 c.591T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.92 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.94 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.94 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.94 rifampicin
rpoC 764077 c.708C>G synonymous_variant 0.94 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.94 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764212 c.843C>T synonymous_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764266 c.897T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764269 c.900G>T synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764338 c.969G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764359 c.990C>G synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764368 c.999C>T synonymous_variant 1.0 rifampicin
rpoC 764371 c.1002G>T synonymous_variant 1.0 rifampicin
rpoC 764383 c.1014C>G synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764438 c.1069C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764455 c.1086G>A synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>T synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 1.0 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764842 c.1473C>T synonymous_variant 1.0 rifampicin
rpoC 764854 c.1485G>C synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764915 c.1546C>T synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765100 c.1731G>C synonymous_variant 1.0 rifampicin
rpoC 765103 c.1734G>T synonymous_variant 1.0 rifampicin
rpoC 765122 c.1753C>T synonymous_variant 1.0 rifampicin
rpoC 765148 c.1779C>G synonymous_variant 1.0 rifampicin
rpoC 765311 p.Ala648Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765327 p.His653Arg missense_variant 1.0 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765346 c.1977C>T synonymous_variant 0.93 rifampicin
rpoC 765350 c.1981_1983delGCGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765357 p.Met663Thr missense_variant 1.0 rifampicin
rpoC 765364 c.1995G>A synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765418 c.2049C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>T synonymous_variant 1.0 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765565 c.2196G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765586 c.2217G>T synonymous_variant 1.0 rifampicin
rpoC 765592 c.2223C>T synonymous_variant 1.0 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765646 c.2277G>A synonymous_variant 1.0 rifampicin
rpoC 765655 c.2286T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765688 c.2319G>A synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765724 c.2355C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.98 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.98 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.98 rifampicin
rpoC 766069 c.2700G>A synonymous_variant 0.97 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.97 rifampicin
rpoC 766087 c.2718C>G synonymous_variant 1.0 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766297 c.2928G>C synonymous_variant 0.94 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.95 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.95 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766354 c.2985C>G synonymous_variant 0.96 rifampicin
rpoC 766357 c.2988C>T synonymous_variant 0.96 rifampicin
rpoC 766363 c.2994G>T synonymous_variant 0.96 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.96 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.96 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.96 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.97 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.97 rifampicin
rpoC 766429 c.3060C>G synonymous_variant 0.97 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>T synonymous_variant 1.0 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.98 rifampicin
rpoC 766541 p.Gly1058Asn missense_variant 1.0 rifampicin
rpoC 766546 p.Glu1059Asp missense_variant 1.0 rifampicin
rpoC 766568 p.Val1067Ile missense_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>T synonymous_variant 1.0 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 0.97 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766660 c.3291G>T synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766891 c.3522G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766960 c.3591C>T synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766966 c.3597G>A synonymous_variant 1.0 rifampicin
rpoC 766972 c.3603G>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767041 c.3672G>A synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767080 c.3711G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767146 c.3777G>C synonymous_variant 1.0 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 1.0 rifampicin
rpoC 767163 p.Asn1265Ser missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767176 c.3807C>T synonymous_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 1.0 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767239 c.3870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpsL 781224 c.-336T>C upstream_gene_variant 1.0 streptomycin
rpsL 781233 c.-327G>C upstream_gene_variant 1.0 streptomycin
rpsL 781236 c.-324G>C upstream_gene_variant 1.0 streptomycin
rpsL 781646 c.87G>A synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781697 c.138C>T synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.95 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.95 streptomycin
rpsL 781769 c.210G>A synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781805 c.246G>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781827 c.268C>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800576 c.-233C>A upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>A upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>A upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800796 c.-13A>C upstream_gene_variant 1.0 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 1.0 linezolid
rplC 800802 c.-6_-5delAG upstream_gene_variant 1.0 linezolid
rplC 800808 c.-1A>G upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800820 c.12G>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64A>C synonymous_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800901 c.93C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800923 p.Ile39Val missense_variant 1.0 linezolid
rplC 801078 p.Asp90Glu missense_variant 1.0 linezolid
rplC 801081 c.273C>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801085 p.Thr93Ala missense_variant 1.0 linezolid Uncertain significance
rplC 801094 p.Gln96Glu missense_variant 1.0 linezolid
rplC 801099 c.291T>C synonymous_variant 1.0 linezolid
rplC 801102 c.294G>C synonymous_variant 1.0 linezolid
rplC 801105 c.297A>G synonymous_variant 1.0 linezolid
rplC 801109 c.301T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801137 p.Ser110Thr missense_variant 1.0 linezolid
rplC 801150 c.342G>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
fbiC 1303509 c.579G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303629 c.699C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303647 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303677 c.747C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303758 c.828G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303768 p.Ser280Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303798 p.Val290Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303826 p.Glu299Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303872 c.942C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303893 c.963G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303896 c.966G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303908 c.978C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303926 c.996G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303932 c.1002G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304055 c.1125C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 1.0 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304070 c.1140C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304076 c.1146C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304100 c.1170G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304130 c.1200G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304192 p.Ala421Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304643 c.1713G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304664 c.1734G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304667 c.1737G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304672 p.Val581Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304684 p.Ala585Gly missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304739 c.1809C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304874 c.1944C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304894 p.Gly655Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304898 c.1968G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304943 c.2013C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304961 c.2031C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305063 c.2133G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305093 c.2163C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305102 c.2172C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305112 p.Asp728Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305125 p.Arg732Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305144 c.2214G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364926 p.Asn172Asp missense_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471984 n.139T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472043 n.198delTinsAA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472301 n.456C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472305 n.460T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472308 n.463T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472312 n.467G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472315 n.470T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474664 n.1007G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474675 n.1018C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474716 n.1059A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475607 n.1950A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475635 n.1978G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673571 c.-631C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673583 c.-619A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673586 c.-616C>T upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673589 c.-613A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673595 c.-607A>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673596 c.157_159delAAGinsGC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 1.0 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673628 c.-574C>A upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673633 p.Ser65Thr missense_variant 1.0 ethionamide
isoniazid
fabG1 1673637 p.Asp66Glu missense_variant 1.0 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673673 c.-529C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673973 c.-229G>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673976 c.-226T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674018 c.-184G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674531 c.330C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674567 c.366C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674603 c.402G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674604 c.403C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674699 c.498C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674735 c.534G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674813 c.612C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674840 c.639C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 c.645C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674861 c.660G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674930 c.729C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674934 c.733C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674945 c.744C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833593 c.52_54delTCTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833794 p.Glu85Gln missense_variant 1.0 pyrazinamide
rpsA 1833799 c.258C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>T synonymous_variant 0.95 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833871 c.330G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834045 c.504G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834288 c.747C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834327 c.786G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834552 c.1011G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834702 c.1161G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>A upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>G upstream_gene_variant 1.0 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 1.0 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
bacA 2064933 c.-205A>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064940 c.-213_-212delCCinsTG upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064957 c.-229G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064963 c.-235G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101837 p.Ala402Val missense_variant 1.0 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 c.1185T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101876 c.1167C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102455 c.588G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102461 c.582G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102469 c.574C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102470 c.573G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102473 c.570C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102476 c.567C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102482 c.561A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102494 c.549T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102497 c.546T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102509 c.534T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102512 c.531G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102542 c.501G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102551 c.492G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102565 c.478C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102812 c.231T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102824 c.219G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102836 c.207T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102839 c.204C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102842 c.201A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102848 c.195G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102857 c.186T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102866 c.177C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102869 c.174G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102902 c.141C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102911 c.132G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2518555 c.441C>T synonymous_variant 1.0 isoniazid
kasA 2518564 c.450C>T synonymous_variant 1.0 isoniazid
kasA 2518574 c.460_462delATCinsGT frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518580 c.466C>T synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518597 c.483C>T synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>T synonymous_variant 0.94 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518612 c.498C>T synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518651 c.537C>T synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>T synonymous_variant 1.0 isoniazid
kasA 2518696 c.582C>G synonymous_variant 1.0 isoniazid
kasA 2518699 c.585C>T synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518723 c.609G>A synonymous_variant 1.0 isoniazid
kasA 2518727 c.613C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518768 c.654C>G synonymous_variant 1.0 isoniazid
kasA 2518780 c.666G>A synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 1.0 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>A synonymous_variant 1.0 isoniazid
kasA 2518801 c.687G>C synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518822 c.708C>A synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518849 c.735G>C synonymous_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
folC 2746437 p.Asp388Asn missense_variant 1.0 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746464 p.Leu379Val missense_variant 1.0 para-aminosalicylic_acid
folC 2746471 c.1128C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746477 c.1120_1122delTTTinsAG frameshift_variant&stop_gained 1.0 para-aminosalicylic_acid
folC 2746480 c.1119A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746486 c.1113C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746495 c.1102_1104delCATinsGC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2746498 c.1101G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746503 c.1096C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746504 c.1095G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746507 c.1092A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746510 c.1089A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746561 c.1038C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746564 c.1035A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.595_597delATTinsGC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747023 c.574_576delGCCinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747035 c.564C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747059 c.540T>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747068 c.529_531delATGinsCC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747101 c.498G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747104 c.495C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747113 c.486C>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747140 c.459G>A synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782495 p.Asp516Glu missense_variant 1.0 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782531 c.1512C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782587 p.Leu486Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782608 p.Gly479Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782612 c.1431T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782615 c.1428G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783281 c.762G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.670_672delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783432 p.Ser204Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783443 c.600G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783458 c.585G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783545 c.496_498delCGCinsAG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783551 c.492G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783592 p.Pro151Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783722 c.321C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783842 c.201C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783848 c.195C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859625 p.Leu265Arg missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859630 c.789G>A synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859635 p.Gln262Glu missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859636 c.783G>A synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859642 c.777C>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859647 p.Gln258Lys missense_variant 1.0 clofazimine
bedaquiline
ribD 2986640 c.-199C>G upstream_gene_variant 1.0 para-aminosalicylic_acid
Rv2681 2996957 c.219T>C synonymous_variant 1.0 capreomycin
Rv2681 2996961 p.Ile75Val missense_variant 1.0 capreomycin
Rv2681 2996969 c.231G>C synonymous_variant 1.0 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 1.0 capreomycin
Rv2681 2996981 c.243C>G synonymous_variant 1.0 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2997011 c.273C>T synonymous_variant 1.0 capreomycin
Rv2681 2997014 c.276T>C synonymous_variant 1.0 capreomycin
Rv2681 2997021 c.283T>C synonymous_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 1.0 capreomycin
Rv2681 2997041 c.303C>G synonymous_variant 1.0 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997059 c.321C>G synonymous_variant 1.0 capreomycin
Rv2681 2997060 p.Asn108Asp missense_variant 1.0 capreomycin
Rv2681 2997065 c.327G>A synonymous_variant 1.0 capreomycin
Rv2681 2997077 c.339C>T synonymous_variant 1.0 capreomycin
Rv2681 2997080 c.342C>G synonymous_variant 1.0 capreomycin
Rv2681 2997083 c.345C>A synonymous_variant 1.0 capreomycin
Rv2752c 3064974 c.1218T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065997 c.195C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066000 c.190_192delATGinsTT frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066260 c.-69T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066288 c.-97G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066294 c.-103C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066300 c.-109G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066303 c.-112C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066315 c.-124C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066329 c.-138C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066336 c.-145C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066345 c.-154C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066350 c.-159T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066351 c.-160G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066366 c.-175C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066370 c.-180_-179delAGinsGC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067223 c.723G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067229 c.717C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067246 p.Thr234Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067253 c.693G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067277 c.669C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 1.0 para-aminosalicylic_acid
thyX 3067287 p.Ala220Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067292 p.Gln218Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067295 c.651C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067316 c.630A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067619 c.327A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067658 c.288C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067682 c.264G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067724 c.222G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067748 c.198C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067771 p.Gly59Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067772 p.Ala58Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067778 c.168C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067823 c.123G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067853 c.93C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067862 c.84C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067868 c.78C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073872 c.598_600delATCinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3073884 c.588C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073902 c.570C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073923 c.547_549delTTGinsCC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073995 c.477G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074001 c.471C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 p.Asp156Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074151 c.321G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074166 c.306G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074195 p.Ile93Val missense_variant 1.0 para-aminosalicylic_acid
thyA 3074199 c.273G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3074220 c.252A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074463 c.9A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074466 c.6G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074469 p.Val1Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074477 c.-6T>C upstream_gene_variant 1.0 para-aminosalicylic_acid
lpqB 3623492 c.1419T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623642 c.1269G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623651 c.1260G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623666 c.1245A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623672 c.1239G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623699 c.1212C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623720 c.1191C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623735 p.Ser392Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623747 c.1164C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623753 c.1158G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624276 p.Arg212His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624307 c.604C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624308 c.603A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624314 c.597C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624320 c.591G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624326 c.585C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624331 c.580C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624341 c.570C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624734 c.177A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624740 c.171G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624779 c.132G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624807 p.Val35Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624809 c.102G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624812 c.99T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624815 c.96A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624818 c.93C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624824 c.87A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624827 c.84C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624847 p.Thr22Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625075 c.-165G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625114 c.-204G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625129 c.-219C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625150 c.-240C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625168 c.-258G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625546 c.-636C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625552 c.-642G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625570 c.-660G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625576 c.-666C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625579 c.-669A>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625582 c.-672C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625585 c.-675G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625615 c.-705G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625683 c.-773C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625726 c.-816G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625801 c.-891G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCA frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625819 c.795G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625897 p.Val239Asn missense_variant 0.96 bedaquiline
rifampicin
mtrB 3625912 c.702G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625936 c.678C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625945 c.669A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625951 c.663A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625957 c.657C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625972 c.642G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625978 c.636T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625993 c.621G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625999 c.615A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626002 c.612G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626006 p.Ser203Asn missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626008 c.606G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626017 c.597T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626029 c.585A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626048 p.Arg189Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626054 p.Leu187Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626062 p.Thr184Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626065 c.549G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626070 p.Ile182Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626077 c.537C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626080 c.534G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626083 c.531G>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626087 p.Ser176Asp missense_variant 0.91 bedaquiline
rifampicin
mtrB 3626092 c.522T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626095 c.519A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626101 p.Gln171Arg missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626110 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626122 c.492C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626146 c.468C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626155 c.459G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626344 c.270G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626350 c.264C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626357 p.Thr86Asn missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626362 c.252A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626386 c.228G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626391 c.223A>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626392 c.222C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626864 c.484_486delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626881 c.-268C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626936 c.-323C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626999 c.-386G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627023 c.-410C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627140 c.-527G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627143 c.207G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627175 c.175C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627342 p.Thr3Ser missense_variant 1.0 bedaquiline
rifampicin
fbiB 3642569 c.1035C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642584 c.1050G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642588 p.Leu352Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642641 c.1107G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642671 c.1137G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642696 c.1162C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642704 c.1170G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642722 c.1188C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642731 c.1197C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877524 c.984C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877567 p.Ser314Thr missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877647 c.861C>T synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877710 c.798C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877806 c.702C>T synonymous_variant 1.0 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 1.0 rifampicin
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 1.0 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>C synonymous_variant 1.0 rifampicin
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877923 c.585C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878007 c.501C>T synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>C synonymous_variant 1.0 rifampicin
rpoA 3878046 c.462T>G synonymous_variant 1.0 rifampicin
rpoA 3878049 c.459G>T synonymous_variant 1.0 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878064 c.444G>C synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878143 p.Gly122Ser missense_variant 1.0 rifampicin
rpoA 3878145 c.363C>G synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878190 c.318C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878208 c.300G>A synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878262 c.246C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 1.0 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 1.0 rifampicin
rpoA 3878418 c.90C>T synonymous_variant 1.0 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878838 c.-331A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878890 c.-383C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878894 c.-387A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878953 c.-446C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 1.0 rifampicin
rpoA 3878986 c.-479G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879033 c.-526C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879034 c.-527G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>T upstream_gene_variant 1.0 rifampicin
rpoA 3879040 c.-533G>T upstream_gene_variant 1.0 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879097 c.-590C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-615_-614delTTinsAG upstream_gene_variant 1.0 rifampicin
rpoA 3879124 c.-618_-617delTGinsGT upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879144 c.-637A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879169 c.-662G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879175 c.-668C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879184 c.-677G>A upstream_gene_variant 1.0 rifampicin
rpoA 3879188 c.-681T>A upstream_gene_variant 1.0 rifampicin
rpoA 3879192 c.-685G>T upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.93 delamanid
pretomanid
ddn 3986673 c.-171C>T upstream_gene_variant 0.93 delamanid
pretomanid
clpC1 4035679 c.2531_*2478del frameshift_variant&stop_lost&splice_region_variant 1.0 pyrazinamide
clpC1 4038270 p.Pro812Ser missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038290 p.Asp805Glu missense_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038305 c.2400C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038449 c.2256C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038458 c.2247G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038461 c.2244G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038479 c.2226C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 1.0 pyrazinamide
clpC1 4038491 c.2214C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 1.0 pyrazinamide
clpC1 4038642 p.Asn688Ser missense_variant 1.0 pyrazinamide
clpC1 4038644 p.Glu687Asp missense_variant 1.0 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038665 c.2040C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038746 c.1959C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038758 c.1947C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038809 c.1896G>A synonymous_variant 0.95 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038827 c.1878G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039037 c.1668T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039258 p.Gln483Glu missense_variant 0.9 pyrazinamide
clpC1 4039259 c.1444_1446delGAGinsAC frameshift_variant&missense_variant 0.9 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039382 c.1323C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039406 c.1299G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039439 c.1266C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039457 c.1248C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039646 c.1059G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039868 c.837C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.805_807delCTCinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040084 c.621C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040087 c.618G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040159 c.546G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040198 c.505_507delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040201 c.504C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040213 c.492T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040231 c.474C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040234 c.471C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040284 c.421C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040312 c.393G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040315 c.390G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040360 c.345G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040366 c.339C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040420 c.285G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040426 c.279T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040441 c.264C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040558 c.147G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040618 c.87C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040663 c.42C>T synonymous_variant 1.0 pyrazinamide
glpK 4138568 c.1188A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138577 c.1179G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138628 c.1128T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138640 c.1116C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138661 c.1095T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138667 c.1089G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138696 p.Pro354Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138711 c.1045C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138714 p.Ala348Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138715 c.1041G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138747 c.1009C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138754 c.1002C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239026 c.-837G>C upstream_gene_variant 1.0 ethambutol
embC 4239336 c.-527T>C upstream_gene_variant 1.0 ethambutol
embC 4239348 c.-515_-513delCTGinsAC upstream_gene_variant 1.0 ethambutol
embC 4239359 c.-504C>G upstream_gene_variant 1.0 ethambutol
embC 4239378 c.-485T>C upstream_gene_variant 1.0 ethambutol
embC 4239384 c.-479C>G upstream_gene_variant 1.0 ethambutol
embC 4239395 c.-468C>T upstream_gene_variant 1.0 ethambutol
embC 4239398 c.-465G>T upstream_gene_variant 1.0 ethambutol
embC 4239401 c.-462A>G upstream_gene_variant 1.0 ethambutol
embC 4239404 c.-459G>C upstream_gene_variant 1.0 ethambutol
embC 4239408 c.-455G>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239413 c.-450C>G upstream_gene_variant 1.0 ethambutol
embC 4239428 c.-435A>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239437 c.-426T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239443 c.-420C>G upstream_gene_variant 1.0 ethambutol
embC 4239448 c.-415G>A upstream_gene_variant 1.0 ethambutol
embC 4239452 c.-411C>T upstream_gene_variant 1.0 ethambutol
embC 4240765 c.903C>G synonymous_variant 1.0 ethambutol
embC 4240768 c.906G>C synonymous_variant 1.0 ethambutol
embC 4240771 c.909G>C synonymous_variant 1.0 ethambutol
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240786 c.924C>A synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240811 c.949_951delTTCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>C synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240858 c.996G>C synonymous_variant 1.0 ethambutol
embC 4240865 c.1003_1005delGCTinsTG frameshift_variant&missense_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240880 p.Ala340Thr missense_variant 1.0 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 1.0 ethambutol
embC 4240936 c.1074A>G synonymous_variant 1.0 ethambutol
embC 4240945 c.1083T>C synonymous_variant 1.0 ethambutol
embC 4240954 c.1092T>C synonymous_variant 1.0 ethambutol
embC 4240957 c.1095C>G synonymous_variant 1.0 ethambutol
embC 4240960 c.1098G>A synonymous_variant 1.0 ethambutol
embC 4240966 c.1104G>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240981 c.1119G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240983 p.Ser374Asn missense_variant 1.0 ethambutol
embC 4240985 c.1123C>A synonymous_variant 1.0 ethambutol
embC 4240990 c.1128A>C synonymous_variant 1.0 ethambutol
embC 4240996 c.1134G>C synonymous_variant 1.0 ethambutol
embC 4241008 c.1146G>C synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>C synonymous_variant 1.0 ethambutol
embC 4241047 c.1185C>A synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241086 c.1224G>C synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241121 p.Ser420Asn missense_variant 1.0 ethambutol
embC 4241125 c.1263G>A synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241142 p.Ile427Thr missense_variant 1.0 ethambutol
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241176 c.1314C>G synonymous_variant 1.0 ethambutol
embC 4241188 c.1326C>T synonymous_variant 1.0 ethambutol
embC 4241194 c.1332C>G synonymous_variant 1.0 ethambutol
embC 4241197 c.1335G>C synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>G synonymous_variant 1.0 ethambutol
embC 4241224 c.1362G>T synonymous_variant 1.0 ethambutol
embC 4241305 c.1443C>G synonymous_variant 1.0 ethambutol
embC 4241390 c.1528C>T synonymous_variant 1.0 ethambutol
embC 4241394 p.Lys511Ser missense_variant 1.0 ethambutol
embC 4241426 c.1564C>T synonymous_variant 1.0 ethambutol
embC 4241470 c.1608C>G synonymous_variant 1.0 ethambutol
embC 4241479 c.1617C>G synonymous_variant 1.0 ethambutol
embC 4241480 c.1618T>C synonymous_variant 1.0 ethambutol
embC 4242229 c.2367C>T synonymous_variant 1.0 ethambutol
embC 4242241 c.2379C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4242244 c.-989C>G upstream_gene_variant 1.0 ethambutol
embC 4242245 p.Thr795Ser missense_variant 1.0 ethambutol
embC 4242269 c.2407_2409delCCAinsAC frameshift_variant&missense_variant 1.0 ethambutol
embC 4242272 p.Gly804Phe missense_variant 1.0 ethambutol
embA 4242277 c.-956T>C upstream_gene_variant 1.0 ethambutol
embC 4242291 p.Asn810Ser missense_variant 1.0 ethambutol
embA 4242301 c.-932G>C upstream_gene_variant 1.0 ethambutol
embA 4242302 c.-931C>T upstream_gene_variant 1.0 ethambutol
embC 4242319 p.Glu819Asp missense_variant 1.0 ethambutol
embA 4242343 c.-890G>C upstream_gene_variant 1.0 ethambutol
embA 4242349 c.-884A>G upstream_gene_variant 1.0 ethambutol
embA 4242352 c.-881G>C upstream_gene_variant 1.0 ethambutol
embA 4242355 c.-878A>C upstream_gene_variant 1.0 ethambutol
embA 4242364 c.-869C>T upstream_gene_variant 1.0 ethambutol
embA 4242377 c.-856C>T upstream_gene_variant 1.0 ethambutol
embA 4244372 c.1140T>G synonymous_variant 1.0 ethambutol
embA 4244396 c.1164T>C synonymous_variant 1.0 ethambutol
embA 4244400 c.1168C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244408 c.1176G>C synonymous_variant 1.0 ethambutol
embA 4244412 c.1180_1182delGTGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244415 c.1183T>C synonymous_variant 1.0 ethambutol
embA 4244426 c.1194G>C synonymous_variant 1.0 ethambutol
embA 4244438 c.1206C>G synonymous_variant 1.0 ethambutol
embA 4244450 c.1218C>G synonymous_variant 1.0 ethambutol
embA 4244459 c.1227G>C synonymous_variant 1.0 ethambutol
embA 4244462 c.1230A>C synonymous_variant 1.0 ethambutol
embA 4244709 p.Ile493Val missense_variant 1.0 ethambutol
embA 4244714 c.1482C>G synonymous_variant 1.0 ethambutol
embA 4244747 c.1515T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244753 c.1521G>C synonymous_variant 1.0 ethambutol
embA 4244757 c.1525_1527delAGCinsTCG synonymous_variant 1.0 ethambutol
embA 4244764 p.Val511Ala missense_variant 1.0 ethambutol
embA 4244768 p.Glu512Asp missense_variant 1.0 ethambutol
embA 4244771 c.1539G>C synonymous_variant 1.0 ethambutol
embA 4244780 c.1548C>G synonymous_variant 1.0 ethambutol
embA 4244786 c.1554G>C synonymous_variant 1.0 ethambutol
embA 4244792 c.1560G>C synonymous_variant 1.0 ethambutol
embA 4244808 p.Phe526Leu missense_variant 1.0 ethambutol
embA 4244838 c.1606C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244843 c.1611G>C synonymous_variant 1.0 ethambutol
embA 4245125 c.1893G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245137 c.1905T>C synonymous_variant 1.0 ethambutol
embA 4245163 p.His644Arg missense_variant 1.0 ethambutol
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245187 p.Thr652Ile missense_variant 1.0 ethambutol
embA 4245198 p.Leu656Ala missense_variant 1.0 ethambutol
embA 4245206 c.1974A>G synonymous_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245210 c.1978C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245213 c.1981_1983delGCAinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245224 c.1992T>C synonymous_variant 1.0 ethambutol
embA 4245254 c.2022C>G synonymous_variant 1.0 ethambutol
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245263 c.2031A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245269 c.2037C>T synonymous_variant 1.0 ethambutol
embA 4245278 c.2046C>T synonymous_variant 1.0 ethambutol
embA 4245285 c.2053T>C synonymous_variant 1.0 ethambutol
embA 4245293 c.2061T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245299 c.2067A>G synonymous_variant 1.0 ethambutol
embA 4245355 p.Ala708Gly missense_variant 1.0 ethambutol
embA 4245362 c.2130G>C synonymous_variant 1.0 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 1.0 ethambutol
embA 4245623 c.2391G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245626 c.-888G>C upstream_gene_variant 1.0 ethambutol
embB 4245635 c.-879A>G upstream_gene_variant 1.0 ethambutol
embB 4245647 c.-867C>G upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embA 4245678 p.Lys816Arg missense_variant 1.0 ethambutol
embB 4245686 c.-828G>C upstream_gene_variant 1.0 ethambutol
embA 4245688 p.Val819Ala missense_variant 1.0 ethambutol
embA 4245693 p.Ile821Val missense_variant 1.0 ethambutol
embA 4245704 c.2472G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245710 c.-804G>T upstream_gene_variant 1.0 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 1.0 ethambutol
embB 4245734 c.-780G>C upstream_gene_variant 1.0 ethambutol
embB 4245737 c.-777A>T upstream_gene_variant 1.0 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embB 4247380 c.867C>G synonymous_variant 1.0 ethambutol
embB 4247387 p.Val292Phe missense_variant 1.0 ethambutol Uncertain significance
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>T synonymous_variant 1.0 ethambutol
embB 4247449 c.936C>T synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247549 p.Ala346Asn missense_variant 1.0 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247729 p.Gly406Pro missense_variant 1.0 ethambutol
embB 4247761 c.1248T>C synonymous_variant 1.0 ethambutol
embB 4247776 c.1263G>T synonymous_variant 1.0 ethambutol
embB 4247779 c.1266C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 1.0 ethambutol
embB 4247794 c.1281G>A synonymous_variant 1.0 ethambutol
embB 4247800 c.1287A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247816 p.Val435Ile missense_variant 1.0 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247827 c.1314C>G synonymous_variant 1.0 ethambutol
embB 4247830 c.1317A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247845 c.1332G>C synonymous_variant 1.0 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247911 p.Leu466Phe missense_variant 1.0 ethambutol
embB 4247920 c.1407T>G synonymous_variant 1.0 ethambutol
embB 4247923 p.His470Gln missense_variant 1.0 ethambutol
embB 4247927 c.1414_1416delCTGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247937 p.Thr475Lys missense_variant 1.0 ethambutol
embB 4247939 c.1426T>C synonymous_variant 0.97 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247948 p.Val479Met missense_variant 1.0 ethambutol
embB 4247960 c.1447C>T synonymous_variant 1.0 ethambutol
embB 4247965 c.1452C>G synonymous_variant 1.0 ethambutol
embB 4247968 c.1455C>G synonymous_variant 1.0 ethambutol
embB 4247974 c.1461C>G synonymous_variant 1.0 ethambutol
embB 4247975 p.Val488Ile missense_variant 1.0 ethambutol Uncertain significance
embB 4247983 c.1470G>C synonymous_variant 1.0 ethambutol
embB 4247992 c.1479G>C synonymous_variant 1.0 ethambutol
embB 4248007 c.1494C>G synonymous_variant 1.0 ethambutol
embB 4248013 c.1500A>G synonymous_variant 1.0 ethambutol
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.97 ethambutol Uncertain significance
embB 4248046 c.1533A>G synonymous_variant 1.0 ethambutol
embB 4248052 c.1539G>A synonymous_variant 1.0 ethambutol
embB 4248064 c.1551G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248106 c.1593C>G synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>T synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>C synonymous_variant 1.0 ethambutol
embB 4248161 c.1648C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>G synonymous_variant 1.0 ethambutol
embB 4248172 c.1659G>C synonymous_variant 1.0 ethambutol
embB 4248190 c.1677G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248200 p.Ile563Val missense_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248214 c.1701C>A synonymous_variant 1.0 ethambutol
embB 4248217 c.1704C>T synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>T synonymous_variant 1.0 ethambutol
embB 4248226 c.1713G>C synonymous_variant 1.0 ethambutol
embB 4248232 c.1719G>C synonymous_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248305 c.1792C>T synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>T synonymous_variant 1.0 ethambutol
embB 4248329 p.Met606Val missense_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 1.0 ethambutol
embB 4248338 c.1825C>T synonymous_variant 1.0 ethambutol
embB 4248349 c.1836G>A synonymous_variant 1.0 ethambutol
embB 4248358 c.1845C>G synonymous_variant 1.0 ethambutol
embB 4248388 c.1875G>A synonymous_variant 1.0 ethambutol
embB 4248406 c.1893G>C synonymous_variant 1.0 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248416 p.Leu635Met missense_variant 1.0 ethambutol
embB 4248424 c.1911G>A synonymous_variant 1.0 ethambutol
embB 4248425 c.1912T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248432 p.Trp640Phe missense_variant 1.0 ethambutol
embB 4248445 c.1932C>T synonymous_variant 1.0 ethambutol
embB 4248460 c.1947C>G synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>G synonymous_variant 1.0 ethambutol
embB 4248503 p.Asp664Asn missense_variant 1.0 ethambutol
embB 4248514 c.2001A>C synonymous_variant 1.0 ethambutol
embB 4248515 p.Val668Ile missense_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249204 c.2691T>C synonymous_variant 1.0 ethambutol
embB 4249213 c.2700C>G synonymous_variant 1.0 ethambutol
embB 4249223 p.Met904Arg missense_variant 1.0 ethambutol
embB 4249227 p.Pro905Gln missense_variant 1.0 ethambutol
embB 4249231 c.2718A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249237 c.2724A>C synonymous_variant 1.0 ethambutol
embB 4249238 p.Ala909Pro missense_variant 1.0 ethambutol
embB 4249246 c.2733A>G synonymous_variant 1.0 ethambutol
embB 4249249 c.2736C>G synonymous_variant 1.0 ethambutol
embB 4249255 c.2742G>A synonymous_variant 1.0 ethambutol
embB 4249273 c.2760C>T synonymous_variant 1.0 ethambutol
embB 4249276 c.2763A>C synonymous_variant 1.0 ethambutol
embB 4249282 c.2769A>C synonymous_variant 1.0 ethambutol
embB 4249321 c.2808A>G synonymous_variant 1.0 ethambutol
embB 4249323 p.Ala937Asp missense_variant 1.0 ethambutol
embB 4249339 c.2826T>C synonymous_variant 1.0 ethambutol
embB 4249340 c.2827_2829delGCCinsAG frameshift_variant&missense_variant 1.0 ethambutol
embB 4249369 c.2856T>C synonymous_variant 1.0 ethambutol
embB 4249381 c.2868A>G synonymous_variant 1.0 ethambutol
embB 4249417 c.2904A>G synonymous_variant 1.0 ethambutol
embB 4249423 p.Asp970Glu missense_variant 1.0 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 1.0 ethambutol
embB 4249441 c.2928A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249447 c.2934G>C synonymous_variant 1.0 ethambutol
embB 4249450 c.2937C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249456 c.2943G>C synonymous_variant 1.0 ethambutol
embB 4249462 c.2949G>C synonymous_variant 1.0 ethambutol
embB 4249486 c.2973T>C synonymous_variant 1.0 ethambutol
embB 4249507 p.Gln998His missense_variant 1.0 ethambutol
embB 4249520 p.Ala1003Arg missense_variant 1.0 ethambutol
embB 4249525 c.3012T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 1.0 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 1.0 ethambutol
embB 4249552 c.3039C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249558 c.3045A>G synonymous_variant 1.0 ethambutol
embB 4249567 c.3054C>T synonymous_variant 1.0 ethambutol
embB 4249573 c.3060T>C synonymous_variant 1.0 ethambutol
embB 4249594 c.3081G>C synonymous_variant 1.0 ethambutol
embB 4249598 c.3085_3087delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4249609 c.3096T>C synonymous_variant 1.0 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249651 c.3138C>G synonymous_variant 1.0 ethambutol
embB 4249654 c.3141C>T synonymous_variant 1.0 ethambutol
embB 4249657 c.3144C>G synonymous_variant 1.0 ethambutol
embB 4249663 c.3150C>G synonymous_variant 1.0 ethambutol
embB 4249666 c.3153C>G synonymous_variant 1.0 ethambutol
embB 4249675 c.3162C>T synonymous_variant 1.0 ethambutol
embB 4249678 c.3165C>T synonymous_variant 1.0 ethambutol
embB 4249693 c.3180T>C synonymous_variant 1.0 ethambutol
embB 4249702 c.3189C>G synonymous_variant 1.0 ethambutol
embB 4249705 c.3192G>C synonymous_variant 1.0 ethambutol
aftB 4268276 c.561G>C synonymous_variant 1.0 ethambutol
aftB 4268282 c.555G>C synonymous_variant 1.0 ethambutol
aftB 4268285 c.552A>G synonymous_variant 1.0 ethambutol
aftB 4268297 c.540A>C synonymous_variant 1.0 ethambutol
aftB 4268300 c.537C>A synonymous_variant 1.0 ethambutol
aftB 4268314 c.523T>C synonymous_variant 1.0 ethambutol
aftB 4268315 c.520_522delGCGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
aftB 4268323 p.Leu172Ile missense_variant 1.0 ethambutol
aftB 4268328 p.Met170Ala missense_variant 1.0 ethambutol
aftB 4268331 p.Gln169Arg missense_variant 1.0 ethambutol
aftB 4268342 c.495C>G synonymous_variant 1.0 ethambutol
aftB 4268345 c.492C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268351 c.486G>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268356 p.Pro161Ala missense_variant 1.0 ethambutol
aftB 4268360 c.477A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268369 c.468C>G synonymous_variant 1.0 ethambutol
aftB 4268374 p.Met155Leu missense_variant 1.0 ethambutol
aftB 4268396 c.441T>C synonymous_variant 1.0 ethambutol
aftB 4268399 c.438C>G synonymous_variant 1.0 ethambutol
aftB 4268404 c.433T>C synonymous_variant 1.0 ethambutol
aftB 4268410 c.427C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268450 c.387A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
ethR 4327651 p.Asn35Arg missense_variant 1.0 ethionamide
ethA 4327656 c.-183A>C upstream_gene_variant 1.0 ethionamide
ethA 4327674 c.-201C>G upstream_gene_variant 1.0 ethionamide
ethR 4327675 p.Ala43Ser missense_variant 1.0 ethionamide
ethA 4327680 c.-207A>G upstream_gene_variant 1.0 ethionamide
ethA 4327686 c.-213C>G upstream_gene_variant 1.0 ethionamide
ethA 4327695 c.-222A>G upstream_gene_variant 1.0 ethionamide
ethA 4327713 c.-240A>G upstream_gene_variant 1.0 ethionamide
ethA 4327716 c.-243G>A upstream_gene_variant 1.0 ethionamide
ethR 4327720 c.172_174delAGGinsCA frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
ethA 4327725 c.-252C>G upstream_gene_variant 1.0 ethionamide