TB-Profiler result

Run: ae693513-f2bb-4b42-844b-9ec63aaf09ac
Summary

Run ID: ae693513-f2bb-4b42-844b-9ec63aaf09ac

Sample name:

Date: 20-07-2023 05:06:31

Number of reads: 862888

Percentage reads mapped: 12.94

Median coverage: 18

Strain: lineage1.2.2.2

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1 Indo-Oceanic RD239 0.9
lineage1.2.2 Indo-Oceanic RD239 0.95
lineage1.2.2.2 Indo-Oceanic RD239 0.96
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser450Leu Assoc w R
isoniazid inhA p.Ser94Ala Uncertain significance
katG p.Trp397* Uncertain significance
p.Ser315Thr Assoc w R
ethambutol embB p.Met306Leu Assoc w R
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin rrs n.517C>T Assoc w R
n.799C>T Uncertain significance
amikacin rrs n.1402C>A Uncertain significance
n.1484G>T Assoc w R - interim
kanamycin rrs n.1402C>A Uncertain significance
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance
n.1484G>T Assoc w R
clofazimine
ethionamide inhA p.Ser94Ala Assoc w R - interim
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761155 p.Ser450Leu missense_variant 0.96 rifampicin Assoc w R
rrs 1472362 n.517C>T non_coding_transcript_exon_variant 0.17 streptomycin Assoc w R
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
aminoglycosides Uncertain significance
amikacin Uncertain significance
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.6 kanamycin Assoc w R
capreomycin Assoc w R
aminoglycosides Uncertain significance
amikacin Assoc w R - interim
inhA 1674481 p.Ser94Ala missense_variant 1.0 isoniazid Uncertain significance
ethionamide Assoc w R - interim
katG 2154921 p.Trp397* stop_gained 0.2 isoniazid Uncertain significance
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R
embB 4247429 p.Met306Leu missense_variant 1.0 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5075 c.-165C>T upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 5394 p.Asn52Ser missense_variant 0.14 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5634 p.Ser132Cys missense_variant 0.13 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 5805 p.Thr189Ile missense_variant 0.14 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6112 p.Met291Ile missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 6202 c.963C>G synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6208 c.969G>C synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6214 c.975G>C synonymous_variant 0.1 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.1 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6223 c.984G>C synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6242 p.Arg335Lys missense_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6399 p.Val387Ala missense_variant 0.13 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrB 6674 c.1437delT frameshift_variant 0.12 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7268 c.-34C>T upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7951 p.Ala217Asp missense_variant 0.11 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8452 p.Ala384Val missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 8815 p.Val505Ala missense_variant 0.12 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
fgd1 490780 c.-3C>G upstream_gene_variant 0.12 delamanid
fgd1 490789 p.Glu3* stop_gained 0.14 delamanid
fgd1 491292 c.510G>A synonymous_variant 0.1 delamanid
fgd1 491295 c.513C>G synonymous_variant 0.1 delamanid
fgd1 491310 c.528C>G synonymous_variant 0.1 delamanid
fgd1 491316 c.534C>G synonymous_variant 0.11 delamanid
fgd1 491319 c.537G>A synonymous_variant 0.1 delamanid
fgd1 491321 p.Ala180Val missense_variant 0.11 delamanid
fgd1 491345 p.Ala188Val missense_variant 0.12 delamanid
fgd1 491355 c.573C>T synonymous_variant 0.11 delamanid
fgd1 491364 c.582T>C synonymous_variant 0.11 delamanid
fgd1 491367 c.585G>C synonymous_variant 0.1 delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 delamanid
rpoB 760148 c.342C>T synonymous_variant 0.14 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.12 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.12 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.12 rifampicin
rpoB 760199 c.393C>G synonymous_variant 0.14 rifampicin
rpoB 760207 p.Ile134Thr missense_variant 0.18 rifampicin
rpoB 760212 p.Asn136His missense_variant 0.18 rifampicin
rpoB 760216 p.Asn137Thr missense_variant 0.18 rifampicin
rpoB 760220 c.414C>T synonymous_variant 0.18 rifampicin
rpoB 760223 c.417T>C synonymous_variant 0.18 rifampicin
rpoB 760313 c.507G>A synonymous_variant 0.13 rifampicin
rpoB 760398 p.Val198Ile missense_variant 0.13 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.11 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.11 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.11 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.11 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.13 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.13 rifampicin
rpoB 760481 c.675G>C synonymous_variant 0.13 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.15 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.17 rifampicin
rpoB 760920 p.Leu372Met missense_variant 0.21 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.19 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.14 rifampicin
rpoB 760958 c.1152G>C synonymous_variant 0.15 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.14 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.11 rifampicin
rpoB 761037 c.1231_1233delTTGinsCTC synonymous_variant 0.12 rifampicin
rpoB 761051 c.1245G>T synonymous_variant 0.14 rifampicin
rpoB 761054 c.1248G>C synonymous_variant 0.14 rifampicin
rpoB 761057 c.1251G>C synonymous_variant 0.12 rifampicin
rpoB 761633 c.1827G>C synonymous_variant 0.13 rifampicin
rpoB 761642 c.1836G>C synonymous_variant 0.1 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 0.11 rifampicin
rpoB 761649 c.1843_1844delAGinsTC synonymous_variant 0.11 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.11 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.11 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 0.13 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.2 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.22 rifampicin
rpoB 761955 p.Ile717Phe missense_variant 0.22 rifampicin
rpoB 761972 c.2166C>G synonymous_variant 0.14 rifampicin
rpoB 762003 p.Asn733Gln missense_variant 0.21 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.16 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.17 rifampicin
rpoB 762015 p.Glu737Gln missense_variant 0.18 rifampicin
rpoB 762020 p.Glu738Asp missense_variant 0.25 rifampicin
rpoB 762030 p.Thr742Ser missense_variant 0.14 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.24 rifampicin
rpoB 762062 c.2256T>C synonymous_variant 0.24 rifampicin
rpoB 762080 c.2274G>C synonymous_variant 0.16 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 0.24 rifampicin
rpoB 762114 p.Ile770Val missense_variant 0.18 rifampicin
rpoB 762119 c.2313C>G synonymous_variant 0.1 rifampicin
rpoB 762122 c.2316C>T synonymous_variant 0.11 rifampicin
rpoB 762128 c.2322G>C synonymous_variant 0.1 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.12 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.12 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.24 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.12 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.22 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.21 rifampicin
rpoB 762156 p.Val784Ile missense_variant 0.11 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.18 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.17 rifampicin
rpoB 762206 c.2400C>G synonymous_variant 0.14 rifampicin
rpoB 762209 c.2403C>T synonymous_variant 0.15 rifampicin
rpoB 762218 c.2412T>C synonymous_variant 0.29 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.2 rifampicin
rpoB 762236 c.2430G>T synonymous_variant 0.13 rifampicin
rpoB 762245 c.2439G>T synonymous_variant 0.14 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.2 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.14 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.18 rifampicin
rpoB 762287 c.2481C>T synonymous_variant 0.13 rifampicin
rpoB 762290 c.2484C>T synonymous_variant 0.13 rifampicin
rpoC 762863 c.-507T>C upstream_gene_variant 0.24 rifampicin
rpoB 762878 p.Ile1024Met missense_variant 0.25 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.46 rifampicin
rpoC 762899 c.-471G>C upstream_gene_variant 0.34 rifampicin
rpoC 762917 c.-453C>G upstream_gene_variant 0.13 rifampicin
rpoC 762920 c.-450C>T upstream_gene_variant 0.23 rifampicin
rpoC 762923 c.-447C>G upstream_gene_variant 0.28 rifampicin
rpoB 762925 p.Thr1040Met missense_variant 0.2 rifampicin
rpoC 762929 c.-441G>C upstream_gene_variant 0.45 rifampicin
rpoB 762939 p.Met1045Leu missense_variant 0.2 rifampicin
rpoB 762942 p.Ile1046Val missense_variant 0.2 rifampicin Uncertain significance
rpoC 762947 c.-423C>G upstream_gene_variant 0.14 rifampicin
rpoC 762959 c.-411G>T upstream_gene_variant 0.11 rifampicin
rpoC 762962 c.-408C>T upstream_gene_variant 0.2 rifampicin
rpoC 762971 c.-399G>C upstream_gene_variant 0.2 rifampicin
rpoC 762980 c.-390T>C upstream_gene_variant 0.15 rifampicin
rpoC 762983 c.-387C>T upstream_gene_variant 0.39 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.43 rifampicin
rpoC 762995 c.-375G>C upstream_gene_variant 0.27 rifampicin
rpoB 763005 p.Cys1067Val missense_variant 0.16 rifampicin
rpoC 763013 c.-357C>G upstream_gene_variant 0.12 rifampicin
rpoB 763014 p.Met1070Leu missense_variant 0.12 rifampicin
rpoB 763017 p.Gln1071Glu missense_variant 0.13 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.13 rifampicin
rpoC 763028 c.-342T>C upstream_gene_variant 0.3 rifampicin
rpoC 763031 c.-339T>C upstream_gene_variant 1.0 rifampicin
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.27 rifampicin
rpoC 763070 c.-300T>C upstream_gene_variant 0.24 rifampicin
rpoB 763074 p.Thr1090Val missense_variant 0.1 rifampicin
rpoC 763082 c.-288C>A upstream_gene_variant 0.11 rifampicin
rpoC 763085 c.-285C>T upstream_gene_variant 0.11 rifampicin
rpoC 763088 c.-282C>G upstream_gene_variant 0.21 rifampicin
rpoC 763115 c.-255T>G upstream_gene_variant 0.13 rifampicin
rpoB 763116 p.Glu1104Gln missense_variant 0.12 rifampicin
rpoC 763127 c.-243G>C upstream_gene_variant 0.13 rifampicin
rpoC 763136 c.-234C>T upstream_gene_variant 0.12 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.12 rifampicin
rpoC 763145 c.-225G>A upstream_gene_variant 0.13 rifampicin
rpoC 763442 p.Tyr25His missense_variant 0.17 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.44 rifampicin
rpoC 763462 c.93G>C synonymous_variant 0.32 rifampicin
rpoC 763465 c.96G>A synonymous_variant 0.11 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.42 rifampicin
rpoC 763483 c.114G>C synonymous_variant 0.56 rifampicin
rpoC 763486 c.117T>G synonymous_variant 0.43 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.44 rifampicin
rpoC 763497 p.Lys43Met missense_variant 0.16 rifampicin
rpoC 763504 c.135C>G synonymous_variant 0.15 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.38 rifampicin
rpoC 763517 p.Lys50Arg missense_variant 0.11 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.48 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.18 rifampicin
rpoC 763534 c.165T>C synonymous_variant 0.62 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.59 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.71 rifampicin
rpoC 763550 p.Tyr61Asn missense_variant 0.2 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.42 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.38 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.43 rifampicin
rpoC 763609 c.240C>G synonymous_variant 0.1 rifampicin
rpoC 763619 c.250_252delCGCinsAGG synonymous_variant 0.11 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.47 rifampicin
rpoC 763627 p.Lys86Asn missense_variant 0.2 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.21 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.14 rifampicin
rpoC 763660 c.291T>C synonymous_variant 0.18 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.13 rifampicin
rpoC 763884 p.Ala172Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763886 c.517C>A synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.12 rifampicin
rpoC 764077 c.708C>G synonymous_variant 0.13 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.14 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.14 rifampicin
rpoC 764097 c.729_732delACTC frameshift_variant 0.15 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.19 rifampicin
rpoC 764143 c.774G>C synonymous_variant 0.19 rifampicin
rpoC 764147 p.Ser260Ala missense_variant 0.19 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.12 rifampicin
rpoC 764164 p.Ile265Met missense_variant 0.12 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.11 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 0.13 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.13 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.15 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.15 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.15 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.18 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.18 rifampicin
rpoC 764435 c.1066_1068delAGGinsCGT synonymous_variant 0.18 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.18 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.2 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.38 rifampicin
rpoC 764530 c.1161C>T synonymous_variant 0.15 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.25 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.38 rifampicin
rpoC 764544 p.Thr392Ser missense_variant 0.12 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.47 rifampicin
rpoC 764560 c.1191T>G synonymous_variant 0.16 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.29 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.4 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.4 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.25 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.3 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.49 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.23 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.27 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 0.11 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.26 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.21 rifampicin
rpoC 764672 p.Gln435Glu missense_variant 0.11 rifampicin
rpoC 764677 c.1308C>G synonymous_variant 0.26 rifampicin
rpoC 764678 p.Lys437Gln missense_variant 0.18 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.12 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.29 rifampicin
rpoC 764705 p.Leu446Asp missense_variant 0.17 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.14 rifampicin
rpoC 764722 c.1353G>C synonymous_variant 0.24 rifampicin
rpoC 764731 c.1362G>C synonymous_variant 0.21 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.22 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.17 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.32 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.28 rifampicin
rpoC 764755 c.1386C>T synonymous_variant 0.15 rifampicin
rpoC 764759 p.Asn464Asp missense_variant 0.18 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.23 rifampicin
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.38 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.16 rifampicin
rpoC 764804 p.Gln479Phe missense_variant 0.12 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.17 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.23 rifampicin
rpoC 764818 c.1449G>C synonymous_variant 0.13 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.22 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 0.12 rifampicin
rpoC 764843 p.Ala492Thr missense_variant 0.24 rifampicin
rpoC 764857 c.1488G>C synonymous_variant 0.17 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.17 rifampicin
rpoC 764872 c.1503A>C synonymous_variant 0.19 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.13 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 0.13 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.13 rifampicin
rpoC 764938 p.Gln523His missense_variant 0.15 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.12 rifampicin
rpoC 764956 c.1587T>C synonymous_variant 0.25 rifampicin
rpoC 764958 p.Glu530Ala missense_variant 0.17 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.17 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.23 rifampicin
rpoC 764971 c.1602C>G synonymous_variant 0.14 rifampicin
rpoC 764983 c.1614T>C synonymous_variant 0.13 rifampicin
rpoC 765579 p.Leu737Arg missense_variant 1.0 rifampicin Uncertain significance
rpoC 765862 p.Phe831Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 767190 p.Pro1274His missense_variant 0.11 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776224 p.Gly753* stop_gained 0.12 clofazimine
bedaquiline
mmpL5 777140 c.1341G>A synonymous_variant 0.12 clofazimine
bedaquiline
mmpL5 777409 p.Ile358Val missense_variant 0.11 clofazimine
bedaquiline
mmpR5 778295 c.-695C>T upstream_gene_variant 0.12 clofazimine
bedaquiline
mmpS5 779613 c.-708C>T upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 779625 c.-720G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
rpsL 781794 p.Met79Val missense_variant 0.13 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.14 streptomycin
rpsL 781803 p.Val82Ile missense_variant 0.13 streptomycin
rpsL 781817 c.258G>C synonymous_variant 0.14 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.14 streptomycin
rpsL 781827 c.268C>T synonymous_variant 0.12 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.15 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.15 streptomycin
rplC 800807 c.-2C>G upstream_gene_variant 0.25 linezolid
rplC 800833 p.Thr9Ala missense_variant 0.22 linezolid
rplC 801064 c.256C>T synonymous_variant 0.11 linezolid
fbiC 1302941 c.13_14delGT frameshift_variant 0.2 delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.2 delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.18 delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.17 delamanid
fbiC 1303590 c.660A>C synonymous_variant 0.13 delamanid
fbiC 1303756 p.Ala276Ser missense_variant 0.11 delamanid
fbiC 1304084 p.Gly385Val missense_variant 0.11 delamanid
fbiC 1305061 p.Gly711Trp missense_variant 0.11 delamanid
Rv1258c 1406181 p.Ile387Thr missense_variant 0.14 streptomycin
pyrazinamide
isoniazid
embR 1417019 p.Cys110Tyr missense_variant 1.0 ethambutol Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471854 n.9G>T non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471876 n.31G>A non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin Uncertain significance
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471919 n.74_75insC non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.38 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.33 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471981 n.136C>G non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.25 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.38 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472107 n.262A>G non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.55 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.15 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.19 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.23 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.65 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.17 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.52 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.16 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.39 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472312 n.468_470delGAT non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.35 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472326 n.481T>G non_coding_transcript_exon_variant 0.16 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472333 n.488G>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.62 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.19 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472390 n.545T>A non_coding_transcript_exon_variant 0.19 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.35 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472415 n.570T>G non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.16 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.38 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.28 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.26 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.33 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.28 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.28 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.43 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.46 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.28 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.28 linezolid
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472497 n.652G>A non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.37 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.58 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.33 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.43 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.19 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.4 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.34 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.34 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.43 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.19 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.39 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.32 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.46 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.43 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.7 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.4 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.55 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.69 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.23 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.28 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.35 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.4 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.39 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.13 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.52 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472786 n.941C>G non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.23 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.46 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.19 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472827 n.982G>C non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.24 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.29 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472841 n.996G>A non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.19 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.23 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.24 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.27 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.45 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.46 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.5 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.16 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.44 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.36 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.35 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.18 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.22 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.25 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.26 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.16 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.39 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.3 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.44 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.48 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.12 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.51 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.52 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.1 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473120 n.1275C>T non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.55 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.33 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.57 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.31 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.69 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.14 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473226 n.1381C>G non_coding_transcript_exon_variant 0.21 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.36 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.45 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.77 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.65 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.52 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.53 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.32 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.24 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin
aminoglycosides
streptomycin
rrl 1473668 n.11C>G non_coding_transcript_exon_variant 0.15 linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.17 linezolid Uncertain significance
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 0.17 linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.25 linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.23 linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.29 linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.27 linezolid
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.25 linezolid
rrl 1473802 n.145C>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1473814 n.157A>G non_coding_transcript_exon_variant 0.21 linezolid
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1473830 n.173T>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473862 n.205C>T non_coding_transcript_exon_variant 0.16 linezolid
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.11 linezolid
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.17 linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.35 linezolid
rrl 1473887 n.230T>G non_coding_transcript_exon_variant 0.15 linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.29 linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.27 linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.45 linezolid
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474182 n.525C>G non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.48 linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.21 linezolid Uncertain significance
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.13 linezolid
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.57 linezolid
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.14 linezolid
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.37 linezolid Uncertain significance
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.38 linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.28 linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.27 linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.1 linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.1 linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.36 linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.1 linezolid
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.2 linezolid Uncertain significance
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.48 linezolid
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.25 linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.41 linezolid
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.36 linezolid
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.39 linezolid
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.54 linezolid
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.48 linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.48 linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.77 linezolid
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.5 linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.5 linezolid
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.34 linezolid
rrl 1474582 n.925T>A non_coding_transcript_exon_variant 0.21 linezolid
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.16 linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.25 linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.42 linezolid
rrl 1474660 n.1003G>A non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.26 linezolid
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.52 linezolid
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474688 n.1031G>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474690 n.1033C>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.67 linezolid
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.3 linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.44 linezolid
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.2 linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.44 linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.28 linezolid
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.18 linezolid
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.16 linezolid
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.16 linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.62 linezolid
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.22 linezolid
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.11 linezolid
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.44 linezolid
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.24 linezolid
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.25 linezolid
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.41 linezolid
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.54 linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.37 linezolid
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474852 n.1195T>C non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.35 linezolid
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.28 linezolid
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.7 linezolid
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.16 linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.62 linezolid
rrl 1474917 n.1260G>T non_coding_transcript_exon_variant 0.19 linezolid
rrl 1474918 n.1261T>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.15 linezolid
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.27 linezolid Uncertain significance
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.27 linezolid
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.23 linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.23 linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.19 linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.19 linezolid
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475137 n.1480A>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.31 linezolid
rrl 1475173 n.1516A>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.19 linezolid
rrl 1475490 n.1833C>A non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.27 linezolid
rrl 1475515 n.1858G>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475517 n.1860C>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.47 linezolid
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.45 linezolid
rrl 1475540 n.1883C>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.47 linezolid
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1475551 n.1894T>G non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475553 n.1896G>C non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475555 n.1898T>G non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475562 n.1905C>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475564 n.1907C>A non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475574 n.1917C>G non_coding_transcript_exon_variant 0.19 linezolid
rrl 1475576 n.1919C>A non_coding_transcript_exon_variant 0.19 linezolid
rrl 1475596 n.1939G>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.31 linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.41 linezolid
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1475707 n.2050T>C non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.22 linezolid
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.55 linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.41 linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.45 linezolid
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.13 linezolid
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.23 linezolid
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.15 linezolid
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.34 linezolid
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.44 linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.55 linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.69 linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.28 linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.39 linezolid
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.51 linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.53 linezolid
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.11 linezolid
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.26 linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.51 linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.51 linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.51 linezolid
rrl 1475953 n.2296A>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.49 linezolid
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.51 linezolid
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.62 linezolid
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.28 linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.62 linezolid Uncertain significance
rrl 1475991 n.2334T>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.33 linezolid Uncertain significance
rrl 1475996 n.2339T>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.15 linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.19 linezolid Uncertain significance
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476078 n.2421C>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476080 n.2423T>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.43 linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.27 linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.2 linezolid
rrl 1476117 n.2460G>A non_coding_transcript_exon_variant 0.11 linezolid
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.51 linezolid
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.36 linezolid
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.48 linezolid
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.64 linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.6 linezolid
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.64 linezolid
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.42 linezolid
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.65 linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.68 linezolid
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.45 linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.18 linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.54 linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.76 linezolid Uncertain significance
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.16 linezolid
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.55 linezolid
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.28 linezolid
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.66 linezolid
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.39 linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.22 linezolid
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.11 linezolid
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.34 linezolid
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.26 linezolid
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.27 linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.17 linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.48 linezolid
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.42 linezolid
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.14 linezolid
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.49 linezolid
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.25 linezolid
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.49 linezolid
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.39 linezolid
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.49 linezolid
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.53 linezolid
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.3 linezolid
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.3 linezolid
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.36 linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.54 linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.68 linezolid
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.16 linezolid
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.44 linezolid
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476534 n.2877A>T non_coding_transcript_exon_variant 0.13 linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.51 linezolid
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.39 linezolid
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.41 linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.26 linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.18 linezolid
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.13 linezolid
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.14 linezolid
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.46 linezolid
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.15 linezolid
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.19 linezolid
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.12 linezolid
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.1 linezolid
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.35 linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.35 linezolid
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.16 linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.24 linezolid
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.11 linezolid
rpsA 1833856 c.315A>G synonymous_variant 0.17 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.11 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.11 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.12 pyrazinamide
rpsA 1833893 p.Ala118Thr missense_variant 0.13 pyrazinamide
rpsA 1833896 p.Leu119Ile missense_variant 0.13 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.13 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.13 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.13 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.13 pyrazinamide
rpsA 1833921 p.Lys127Thr missense_variant 0.13 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.13 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.17 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.38 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.23 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.45 pyrazinamide
rpsA 1833985 c.444G>T synonymous_variant 0.23 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.14 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.36 pyrazinamide
rpsA 1833997 c.456G>T synonymous_variant 0.38 pyrazinamide
rpsA 1834000 c.459G>T synonymous_variant 0.42 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 0.58 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.17 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.83 pyrazinamide
rpsA 1834039 c.498C>T synonymous_variant 0.58 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 0.54 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834090 c.549G>T synonymous_variant 0.42 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.25 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.25 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.25 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834123 c.582C>T synonymous_variant 0.17 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.1 pyrazinamide
rpsA 1834213 c.672G>A synonymous_variant 0.14 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.13 pyrazinamide
rpsA 1834228 c.687C>T synonymous_variant 0.12 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.12 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.17 pyrazinamide
rpsA 1834240 c.699T>G synonymous_variant 0.14 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.21 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.25 pyrazinamide
rpsA 1834264 c.723G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.13 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.26 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834307 p.Asp256Gln missense_variant 0.24 pyrazinamide
rpsA 1834327 c.786G>C synonymous_variant 0.1 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.35 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.32 pyrazinamide
rpsA 1834369 c.828C>G synonymous_variant 0.23 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834395 p.Arg285Gln missense_variant 0.32 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.24 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.27 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.26 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.16 pyrazinamide
rpsA 1834459 c.918G>C synonymous_variant 0.11 pyrazinamide
rpsA 1834468 c.927A>C synonymous_variant 0.21 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.11 pyrazinamide
rpsA 1834477 c.936C>G synonymous_variant 0.21 pyrazinamide
rpsA 1834483 p.Glu314Asp missense_variant 0.2 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.24 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.29 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.14 pyrazinamide
rpsA 1834538 p.Val333Ile missense_variant 0.16 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.12 pyrazinamide
rpsA 1834546 p.Asp335Glu missense_variant 0.14 pyrazinamide
rpsA 1834552 c.1011G>C synonymous_variant 0.12 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.14 pyrazinamide
rpsA 1834556 p.Ala339Gln missense_variant 0.13 pyrazinamide
rpsA 1834572 p.Ala344Val missense_variant 0.12 pyrazinamide
rpsA 1834577 p.Val346Ile missense_variant 0.12 pyrazinamide
rpsA 1834772 p.Arg411Cys missense_variant 0.14 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin
tlyA 1917990 c.51G>A synonymous_variant 0.12 capreomycin
ndh 2102240 p.Arg268His missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
katG 2154155 p.Leu653Met missense_variant 0.11 isoniazid
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Uncertain significance
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168728 p.Gly629Ser missense_variant 0.17 pyrazinamide
PPE35 2168742 p.Gly624Asp missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2169359 p.Asn418Lys missense_variant 0.15 pyrazinamide
PPE35 2170506 p.Thr36Ile missense_variant 0.14 pyrazinamide
PPE35 2170777 c.-165C>T upstream_gene_variant 0.11 pyrazinamide
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
pncA 2289769 c.-528G>A upstream_gene_variant 0.14 pyrazinamide
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
eis 2714466 p.Trp289Cys missense_variant 0.14 kanamycin
amikacin
eis 2714755 p.Pro193Leu missense_variant 0.1 kanamycin
amikacin
eis 2715338 c.-6G>C upstream_gene_variant 0.13 kanamycin
amikacin
folC 2746154 p.Phe482Ser missense_variant 0.15 para-aminosalicylic_acid
folC 2747627 c.-29C>A upstream_gene_variant 0.1 para-aminosalicylic_acid
pepQ 2860322 c.97C>T synonymous_variant 0.14 clofazimine
bedaquiline
pepQ 2860520 c.-102C>T upstream_gene_variant 0.13 clofazimine
bedaquiline
thyX 3067727 c.219A>G synonymous_variant 0.12 para-aminosalicylic_acid
ald 3086846 c.27C>A synonymous_variant 0.15 cycloserine
Rv3083 3448702 p.Arg67Ser missense_variant 0.15 ethionamide Uncertain significance
Rv3083 3448714 p.Asp71His missense_variant 1.0 ethionamide Uncertain significance
Rv3083 3449086 p.Ala195Ser missense_variant 0.11 ethionamide
Rv3083 3449231 p.Gly243Val missense_variant 0.1 ethionamide
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0 capreomycin
amikacin
fprA 3474376 p.Ala124Thr missense_variant 0.13 capreomycin Uncertain significance
amikacin Uncertain significance
fprA 3474597 c.591C>A synonymous_variant 1.0 capreomycin
amikacin
fprA 3474905 c.905_933delTGGCGGCCAAGGACACCGGCGAGCGCGAG frameshift_variant 0.15 capreomycin
amikacin
fprA 3475159 p.Asn385Asp missense_variant 1.0 capreomycin Uncertain significance
amikacin Uncertain significance
fbiB 3640593 c.-942C>T upstream_gene_variant 0.11 delamanid
alr 3840760 p.Gln221Lys missense_variant 0.14 cycloserine
rpoA 3878405 p.Gly35Cys missense_variant 0.13 rifampicin
clpC1 4038313 p.Gln798* stop_gained 0.11 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.11 pyrazinamide
clpC1 4038374 c.2331C>T synonymous_variant 0.11 pyrazinamide
clpC1 4038383 c.2322G>T synonymous_variant 0.11 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.11 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 0.11 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.12 pyrazinamide
clpC1 4038404 c.2301G>C synonymous_variant 0.11 pyrazinamide
clpC1 4038461 c.2244G>A synonymous_variant 0.12 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.11 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.1 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.13 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.12 pyrazinamide
clpC1 4039088 c.1617G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.14 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.14 pyrazinamide
clpC1 4039115 p.Lys530Arg missense_variant 0.17 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.17 pyrazinamide
clpC1 4039128 p.Lys526Arg missense_variant 0.14 pyrazinamide
clpC1 4039132 p.Val525Ile missense_variant 0.12 pyrazinamide
clpC1 4039139 p.Glu522Asp missense_variant 0.13 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.14 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.14 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.14 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.13 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.13 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.13 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.13 pyrazinamide
clpC1 4039195 p.Thr504Ser missense_variant 0.14 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.14 pyrazinamide
clpC1 4039390 p.Ile439Val missense_variant 0.12 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039616 c.1089G>T synonymous_variant 0.11 pyrazinamide
clpC1 4039631 p.Ile358Met missense_variant 0.13 pyrazinamide
clpC1 4039642 p.Thr355Ala missense_variant 0.12 pyrazinamide
clpC1 4039647 p.Glu353Ala missense_variant 0.18 pyrazinamide
clpC1 4039651 p.Val352Leu missense_variant 0.17 pyrazinamide
clpC1 4039654 p.Thr351Ser missense_variant 0.3 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039661 p.Gly348Asp missense_variant 0.26 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039670 p.Val345Ile missense_variant 0.25 pyrazinamide
clpC1 4039697 p.Ala336Ser missense_variant 0.1 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.25 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.26 pyrazinamide
clpC1 4039727 p.Asp326Glu missense_variant 0.21 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.24 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.17 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.11 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.11 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.12 pyrazinamide
clpC1 4039838 p.Leu289Ile missense_variant 0.14 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.1 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.17 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.19 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.14 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.17 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.1 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.11 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.11 pyrazinamide
clpC1 4039982 p.Thr241Ile missense_variant 0.1 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.14 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.11 pyrazinamide
clpC1 4040129 p.Gly192Gln missense_variant 0.12 pyrazinamide
clpC1 4040153 c.552A>G synonymous_variant 0.1 pyrazinamide
clpC1 4040162 c.543G>T synonymous_variant 0.1 pyrazinamide
clpC1 4040166 p.Ala180Gln missense_variant 0.11 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.16 pyrazinamide
clpC1 4040517 p.Val63Ala missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4040719 c.-15A>G upstream_gene_variant 1.0 pyrazinamide Uncertain significance
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Uncertain significance
embC 4240694 p.Ile278Val missense_variant 0.12 ethambutol
embC 4241042 p.Asn394Asp missense_variant 1.0 ethambutol Uncertain significance
embA 4242643 c.-590C>T upstream_gene_variant 1.0 ethambutol
embA 4244786 c.1554G>T synonymous_variant 0.11 ethambutol
embA 4244926 p.Phe565Tyr missense_variant 0.11 ethambutol
embA 4245314 c.2082G>A synonymous_variant 0.1 ethambutol
embA 4245969 p.Pro913Ser missense_variant 1.0 ethambutol Uncertain significance
embA 4246443 p.Asp1071Tyr missense_variant 0.12 ethambutol
embB 4246871 p.Ala120Pro missense_variant 0.13 ethambutol
embB 4246951 c.438A>G synonymous_variant 0.15 ethambutol
embB 4247422 c.909C>A synonymous_variant 0.11 ethambutol
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Uncertain significance
embB 4248112 c.1599C>T synonymous_variant 0.12 ethambutol
aftB 4267319 c.1518C>T synonymous_variant 0.12 capreomycin
amikacin
aftB 4267327 p.Val504Leu missense_variant 0.11 capreomycin
amikacin
aftB 4267332 p.Val502Gly missense_variant 0.11 capreomycin
amikacin
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Uncertain significance
aftB 4269606 c.-770T>C upstream_gene_variant 1.0 capreomycin
amikacin
ethA 4326148 c.1326G>T synonymous_variant 1.0 ethionamide
ethA 4326439 p.Asn345Lys missense_variant 1.0 ethionamide Uncertain significance
ethA 4328456 c.-983G>A upstream_gene_variant 0.14 ethionamide
whiB6 4338203 p.Arg107Cys missense_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0 streptomycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin
gid 4407848 p.Ala119Thr missense_variant 1.0 streptomycin Uncertain significance
gid 4407873 c.330G>T synonymous_variant 1.0 streptomycin
gid 4408111 p.Val31Ala missense_variant 1.0 streptomycin