TB-Profiler result

Run: ERR067699
Summary

Run ID: ERR067699

Sample name:

Date: 2024-10-05T04:21:28.334154

Number of reads: 276324

Percentage reads mapped: 10.01

Median coverage: 2.0

Strain: La1;lineage2;lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.12
lineage4 Euro-American None 0.98
lineage4.9 Euro-American (H37Rv-like) None 0.87
La1 M.bovis None 0.05
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 1.0 isoniazid
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 597 c.597C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 610 c.610C>T synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.93 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.93 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.96 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.96 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.97 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 933 c.933C>G synonymous_variant 0.98 isoniazid
dnaA 954 c.954G>A synonymous_variant 1.0 isoniazid
dnaA 955 c.955_957delAGAinsCGT synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>T synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>T synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 1.0 isoniazid
dnaA 1011 c.1011C>G synonymous_variant 1.0 isoniazid
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6193 c.954G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6203 c.964_966delAGCinsTCG synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6262 c.1023G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6304 c.-998C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6325 c.-977C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6329 p.Glu364Gln missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6784 c.-518C>T upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6787 c.-515G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 p.Ile519Leu missense_variant 0.95 levofloxacin
moxifloxacin
gyrB 6797 p.Gly520Ser missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 6808 c.-494C>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.95 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7349 c.48A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7367 p.Gln22His missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7370 c.69G>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7418 c.117C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7658 c.357A>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7661 c.360C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7847 c.546G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7874 c.573G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8141 c.840C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8267 c.966G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8318 c.1017C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8319 c.1018_1019delAGinsTC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8378 c.1077C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8429 c.1128C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 c.1512C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8921 c.1620C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
fgd1 491547 c.765A>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 491569 p.Asp263Asn missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491580 p.Ile266Met missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491592 c.810G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fgd1 491603 p.Ala274Glu missense_variant 0.95 pretomanid
delamanid
clofazimine
fgd1 491607 c.825G>T synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>C synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.93 pretomanid
delamanid
clofazimine
fgd1 491643 c.861G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491646 c.864G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 0.88 pretomanid
delamanid
clofazimine
mshA 575737 c.390T>C synonymous_variant 0.82 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 0.93 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>G synonymous_variant 0.94 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.94 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 0.9 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.9 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.9 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.9 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.9 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.92 isoniazid
ethionamide
mshA 575800 c.453G>T synonymous_variant 0.92 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.93 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.95 isoniazid
ethionamide
mshA 575845 c.498C>G synonymous_variant 0.94 isoniazid
ethionamide
mshA 575848 c.501C>T synonymous_variant 0.94 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575875 c.528C>G synonymous_variant 0.92 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.92 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.85 isoniazid
ethionamide
ccsA 620613 c.723C>T synonymous_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 620619 c.729G>C synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 620634 c.744C>G synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620670 c.780C>T synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620724 c.834C>T synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.96 kanamycin
capreomycin
amikacin
ccsA 620736 c.846G>T synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>G synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620760 c.870C>A synonymous_variant 0.9 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620764 p.Ala292Ser missense_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.88 kanamycin
capreomycin
amikacin
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.82 ethionamide
Rv0565c 657656 c.-186C>T upstream_gene_variant 0.83 ethionamide
Rv0565c 657668 c.-200_-198delACCinsGCG upstream_gene_variant 0.85 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.79 ethionamide
Rv0565c 657690 c.-220C>A upstream_gene_variant 0.79 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCAG upstream_gene_variant 0.8 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.73 ethionamide
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.97 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.97 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.97 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.93 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.83 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.79 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760091 c.285G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.87 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.94 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760271 c.465C>G synonymous_variant 1.0 rifampicin
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>A synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760412 c.606C>T synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>G synonymous_variant 0.91 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760755 p.His317Asn missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760778 c.972G>C synonymous_variant 1.0 rifampicin
rpoB 760784 c.978G>C synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 1.0 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760848 p.Thr348Ser missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 1.0 rifampicin
rpoB 760880 c.1074G>C synonymous_variant 1.0 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760887 p.Thr361Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 760916 c.1110C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 0.94 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.94 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.94 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.94 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.94 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.95 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 0.9 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 0.93 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761126 c.1320G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ser missense_variant 0.9 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.9 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.6 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.98 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.98 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.92 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.88 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.88 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.88 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.91 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.89 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.89 rifampicin
rpoB 761736 p.Ile644Val missense_variant 0.75 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 0.81 rifampicin
rpoB 761753 c.1947C>G synonymous_variant 0.84 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.86 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.86 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.86 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.86 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.92 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.97 rifampicin
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 0.97 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.95 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.95 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.95 rifampicin
rpoB 762134 c.2328C>T synonymous_variant 0.95 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.9 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.91 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 1.0 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762917 c.-453C>T upstream_gene_variant 1.0 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>G upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763220 c.-150G>A upstream_gene_variant 0.93 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.93 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.93 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.93 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 0.93 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.91 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.94 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.94 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.94 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.94 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.95 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.96 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763621 c.252C>T synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.98 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.98 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.97 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.98 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.96 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.98 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763790 p.Glu141Thr missense_variant 0.89 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.85 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.85 rifampicin
rpoC 763819 c.450G>C synonymous_variant 0.81 rifampicin
rpoC 763825 c.456G>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.92 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.93 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.93 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.92 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.94 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.95 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.9 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.89 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.85 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.8 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.8 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.82 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.83 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.83 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.88 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.7 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.7 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.7 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.73 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.64 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.73 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 0.7 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.7 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.7 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.7 rifampicin Uncertain significance
rpoC 764227 c.858G>T synonymous_variant 0.93 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 1.0 rifampicin
rpoC 764293 c.924G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.97 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>T synonymous_variant 0.97 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>T synonymous_variant 1.0 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.98 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.95 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.96 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.95 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.9 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 0.86 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.86 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.87 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765425 p.Lys686Glu missense_variant 0.88 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.92 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.91 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.88 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.9 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765533 p.Tyr722His missense_variant 0.79 rifampicin Uncertain significance
rpoC 765793 c.2424C>G synonymous_variant 0.93 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.93 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.93 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 0.94 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.94 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.97 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.97 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.97 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.97 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.94 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.95 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>A synonymous_variant 0.95 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.95 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.95 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 0.82 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.88 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.88 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.88 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.88 rifampicin
rpoC 766393 c.3024C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766408 c.3039C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766618 c.3249G>T synonymous_variant 0.9 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.91 rifampicin
rpoC 766634 p.Phe1089Ile missense_variant 0.91 rifampicin
rpoC 766638 p.Lys1090Thr missense_variant 0.91 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.91 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.83 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 0.83 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.88 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.88 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.8 rifampicin
rpoC 766694 p.Gln1109Asp missense_variant 0.73 rifampicin
rpoC 766702 c.3333G>C synonymous_variant 0.81 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.84 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 0.84 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.84 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.86 rifampicin
rpoC 766732 c.3363G>T synonymous_variant 0.9 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.91 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.92 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.96 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.96 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.96 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766981 c.3612T>C synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 0.97 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.95 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.86 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.82 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.9 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.89 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767281 c.3912C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767302 c.3933C>G synonymous_variant 0.9 rifampicin
mmpL5 775850 c.2631C>T synonymous_variant 0.73 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 775862 c.2619G>C synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775865 c.2616T>G synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775886 c.2595A>T synonymous_variant 0.87 bedaquiline
clofazimine
mmpL5 775893 p.His863Pro missense_variant 0.72 bedaquiline
clofazimine
mmpL5 775895 p.Ile862Leu missense_variant 0.69 bedaquiline
clofazimine
mmpL5 775898 c.2583G>A synonymous_variant 0.69 bedaquiline
clofazimine
mmpL5 775904 p.Lys859Arg missense_variant 0.69 bedaquiline
clofazimine
mmpL5 775910 c.2571G>C synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775913 c.2568C>G synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 0.88 bedaquiline
clofazimine
mmpL5 776039 p.Ala814Thr missense_variant 0.9 bedaquiline
clofazimine
mmpL5 776051 p.Leu810Val missense_variant 0.85 bedaquiline
clofazimine
mmpL5 776056 p.Val809Leu missense_variant 0.71 bedaquiline
clofazimine
mmpL5 776072 c.2409C>G synonymous_variant 0.95 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.91 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 0.71 bedaquiline
clofazimine
mmpL5 776087 p.Val798Leu missense_variant 0.88 bedaquiline
clofazimine
mmpL5 776090 c.2391C>T synonymous_variant 0.62 bedaquiline
clofazimine
mmpL5 776096 c.2385C>G synonymous_variant 0.62 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 0.96 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776132 c.2349A>C synonymous_variant 0.78 bedaquiline
clofazimine
mmpL5 776678 c.1803G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776683 p.Leu600Met missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776686 p.Ser599Ala missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776693 p.Val596Met missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776715 p.Lys589Pro missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776726 p.Phe585Leu missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776733 p.Ser583Asn missense_variant 1.0 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776741 c.1740C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776744 c.1737C>G synonymous_variant 1.0 bedaquiline
clofazimine
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>G synonymous_variant 1.0 streptomycin
rpsL 781622 c.63C>G synonymous_variant 1.0 streptomycin
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>G synonymous_variant 1.0 streptomycin
rpsL 781667 c.108C>T synonymous_variant 0.95 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800546 c.-263T>C upstream_gene_variant 0.8 linezolid
rplC 800555 c.-254C>A upstream_gene_variant 0.8 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.8 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800753 c.-56C>T upstream_gene_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800921 p.Arg38Leu missense_variant 1.0 linezolid
rplC 800928 c.120C>T synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 0.94 linezolid
rplC 800946 c.138T>C synonymous_variant 0.9 linezolid
rplC 800949 c.141T>C synonymous_variant 0.9 linezolid
rplC 800964 c.156G>C synonymous_variant 0.92 linezolid
rplC 800985 c.177A>G synonymous_variant 0.93 linezolid
rplC 801003 c.195G>C synonymous_variant 0.89 linezolid
rplC 801004 p.Leu66Val missense_variant 0.89 linezolid
rplC 801009 c.201A>C synonymous_variant 0.84 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.8 linezolid
rplC 801027 c.219C>G synonymous_variant 0.78 linezolid
rplC 801030 c.222C>T synonymous_variant 0.75 linezolid
rplC 801039 c.231A>G synonymous_variant 0.79 linezolid
rplC 801045 c.237A>C synonymous_variant 0.8 linezolid
rplC 801046 p.Tyr80His missense_variant 0.8 linezolid
rplC 801171 c.363A>G synonymous_variant 0.8 linezolid
rplC 801174 c.366T>C synonymous_variant 0.8 linezolid
rplC 801195 c.387G>T synonymous_variant 0.79 linezolid
rplC 801205 p.Arg133Lys missense_variant 0.7 linezolid
rplC 801219 c.411C>T synonymous_variant 0.73 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.73 linezolid
rplC 801237 c.429G>C synonymous_variant 0.9 linezolid
rplC 801246 c.438C>T synonymous_variant 0.83 linezolid
rplC 801252 c.444G>C synonymous_variant 0.83 linezolid
fbiC 1303492 c.562T>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303531 p.Met201Leu missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303539 c.609G>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1303548 c.618G>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1303551 c.621G>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303969 p.Val347Ile missense_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1303974 c.1044C>T synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1303998 c.1068T>C synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304001 c.1071C>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304013 c.1083G>T synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304019 c.1089C>T synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiC 1304465 p.Gly512Asp missense_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304472 c.1542T>C synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304481 c.1551T>G synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304490 c.1560C>A synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304493 c.1563C>T synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304496 c.1566T>A synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>C synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304515 p.Ala529Thr missense_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1304700 c.1770G>A synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1304709 c.1779C>G synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.92 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304751 c.1821C>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>T synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304760 c.1830G>C synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304772 c.1842C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304784 c.1854T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304802 c.1872G>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1305360 c.2430G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305361 c.2431C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305381 c.2451G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305393 c.2463T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305396 c.2466C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305399 c.2469A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305400 p.His824Asn missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305405 c.2475A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305417 c.2487C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305420 c.2490C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305423 c.2493T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305429 c.2499G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364757 c.345G>A synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.92 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.95 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.96 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.96 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.96 pyrazinamide
sigE 1364818 c.406_408delCTAinsTTG synonymous_variant 0.96 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.96 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.95 pyrazinamide
sigE 1364859 c.447C>T synonymous_variant 0.95 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.82 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.79 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.8 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.75 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.82 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 0.8 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.8 pyrazinamide
sigE 1365075 c.663G>A synonymous_variant 0.8 pyrazinamide
sigE 1365081 c.669G>C synonymous_variant 0.8 pyrazinamide
sigE 1365087 c.675A>G synonymous_variant 0.8 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.8 pyrazinamide
atpE 1461137 c.93C>G synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.92 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.92 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.92 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.94 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.94 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.89 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.94 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 0.95 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.95 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.82 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.79 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 0.73 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.73 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472037 n.192_193insCTTCC non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473811 n.154C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473833 n.176G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474102 n.445_446insTGAAC non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474106 n.449_453delATCAAinsG non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373_2378delACCTCGinsGCTCAC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
inhA 1673691 c.-511G>C upstream_gene_variant 0.83 isoniazid
ethionamide
inhA 1673692 c.-510C>T upstream_gene_variant 0.83 isoniazid
ethionamide
inhA 1673709 c.-493C>G upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsCA upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1673721 c.-481C>T upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 0.93 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1673772 c.-430C>G upstream_gene_variant 0.93 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.86 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.88 isoniazid
ethionamide
inhA 1674489 c.288G>C synonymous_variant 0.89 isoniazid
ethionamide
inhA 1674514 p.Ile105Val missense_variant 0.88 isoniazid
ethionamide
inhA 1674531 c.330C>T synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674534 c.333G>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.91 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 0.91 isoniazid
ethionamide
inhA 1674573 c.372G>A synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.89 isoniazid
ethionamide
inhA 1674601 p.Leu134Ala missense_variant 0.91 isoniazid
ethionamide
inhA 1674610 p.Ile137Val missense_variant 0.92 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674628 c.427_428delTCinsAG synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674636 c.435C>G synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674639 c.438C>A synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 0.88 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674813 c.612C>T synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674816 c.615T>G synonymous_variant 0.92 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674827 p.Glu209Ala missense_variant 0.93 isoniazid
ethionamide
inhA 1674839 p.Ala213Asp missense_variant 0.94 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.94 isoniazid
ethionamide
inhA 1674848 p.Gln216Arg missense_variant 0.95 isoniazid Uncertain significance
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674864 c.663C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674879 c.678T>A synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674883 p.Ile228Val missense_variant 0.95 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674904 p.Ala235Pro missense_variant 0.95 isoniazid
ethionamide
inhA 1674924 c.723G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674930 c.729C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833547 c.6G>A synonymous_variant 0.82 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.86 pyrazinamide
rpsA 1833557 p.Val6Ile missense_variant 0.88 pyrazinamide
rpsA 1833578 p.Val13Ile missense_variant 0.93 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 0.96 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.96 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.96 pyrazinamide
rpsA 1833616 c.75A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.96 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 0.95 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.98 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.98 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.95 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.95 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.96 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.95 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.95 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.96 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.98 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.82 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.71 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.69 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.69 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.64 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.92 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.91 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.91 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.91 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.91 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.91 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.91 linezolid
katG 2155628 p.Ala162Ser missense_variant 0.64 isoniazid
katG 2155632 c.480A>G synonymous_variant 0.86 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.9 isoniazid
katG 2155659 p.Val151Leu missense_variant 0.64 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.64 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.67 isoniazid
katG 2155695 p.Ala139Val missense_variant 0.86 isoniazid
katG 2155698 c.414C>T synonymous_variant 0.67 isoniazid Not assoc w R - Interim
katG 2155716 c.396T>C synonymous_variant 0.89 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.93 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.93 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.94 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.94 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.94 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.94 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.94 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.94 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.89 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.89 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.93 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.95 isoniazid
ahpC 2726609 c.417C>T synonymous_variant 0.95 isoniazid
ahpC 2726624 c.432C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726675 c.483A>T synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726693 c.501C>G synonymous_variant 1.0 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
ahpC 2726709 c.517C>T synonymous_variant 1.0 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 1.0 isoniazid
folC 2747059 c.540T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747083 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747092 c.507C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747097 p.Val168Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747137 c.462G>C synonymous_variant 0.83 para-aminosalicylic_acid
Rv2477c 2782483 c.1560G>C synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783650 p.His131Ala missense_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783671 p.Arg124His missense_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2681 2996236 c.-503C>G upstream_gene_variant 0.82 capreomycin
Rv2681 2996239 c.-500C>T upstream_gene_variant 0.82 capreomycin
Rv2681 2996242 c.-497T>G upstream_gene_variant 0.82 capreomycin
Rv2681 2996245 c.-494C>A upstream_gene_variant 0.82 capreomycin
Rv2681 2996248 c.-491A>T upstream_gene_variant 0.82 capreomycin
Rv2680 2996254 c.150G>A synonymous_variant 0.9 capreomycin Not assoc w R - Interim
Rv2681 2996263 c.-476A>G upstream_gene_variant 0.9 capreomycin
Rv2681 2996266 c.-473T>G upstream_gene_variant 0.9 capreomycin
Rv2681 2996269 c.-470G>T upstream_gene_variant 0.9 capreomycin
Rv2681 2996287 c.-452A>C upstream_gene_variant 0.9 capreomycin
thyX 3067340 c.606G>A synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067364 c.582C>T synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067367 c.579G>T synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067376 c.570G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067388 c.558C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067442 c.504C>A synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073950 c.522G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073980 c.492C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073993 c.478_479delAGinsTC synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074199 c.273G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.93 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 0.94 para-aminosalicylic_acid
thyA 3074220 c.252A>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074229 c.243C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074271 c.201C>G synonymous_variant 0.8 para-aminosalicylic_acid
lpqB 3624643 p.Ile90Leu missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624671 c.240C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624675 p.Asn79Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624680 c.231T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624686 c.225A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624701 c.210T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624704 c.207G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624707 c.204G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625240 c.-330T>C upstream_gene_variant 0.9 rifampicin
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 0.9 rifampicin
bedaquiline
lpqB 3625246 c.-336G>C upstream_gene_variant 0.9 rifampicin
bedaquiline
lpqB 3625252 c.-342G>T upstream_gene_variant 0.9 rifampicin
bedaquiline
lpqB 3625255 c.-345T>C upstream_gene_variant 0.9 rifampicin
bedaquiline
lpqB 3625258 c.-348G>C upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3625262 p.Tyr451Phe missense_variant 0.9 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.9 rifampicin
bedaquiline
lpqB 3625273 c.-363C>G upstream_gene_variant 0.91 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625312 c.-402G>C upstream_gene_variant 0.86 rifampicin
bedaquiline
lpqB 3625318 c.-408G>C upstream_gene_variant 0.8 rifampicin
bedaquiline
lpqB 3625336 c.-426C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3625351 c.1263T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625354 c.-444G>C upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625357 c.-447T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625744 c.870G>A synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625753 p.Ala287Gln missense_variant 0.75 rifampicin
bedaquiline
mtrB 3625762 c.852A>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625768 c.-858G>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626684 c.-71G>A upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626711 p.Thr213Gln missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626723 c.-110C>G upstream_gene_variant 0.94 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.95 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.95 rifampicin
bedaquiline
mtrA 3626749 c.601C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.96 rifampicin
bedaquiline
mtrB 3626773 c.-160C>T upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGT upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3626786 c.-173A>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3626792 c.-179G>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877548 c.960C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877554 c.954G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 1.0 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.94 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 0.96 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.96 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.96 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.96 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.96 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.9 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 0.82 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.82 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.82 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 0.8 rifampicin
rpoA 3877782 c.726T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.8 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.94 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.95 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.92 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.87 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 0.86 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877965 c.543C>G synonymous_variant 0.82 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.8 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878878 c.-371T>C upstream_gene_variant 0.79 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 0.79 rifampicin
rpoA 3878886 c.-379G>A upstream_gene_variant 0.79 rifampicin Uncertain significance
rpoA 3878890 c.-383C>G upstream_gene_variant 0.79 rifampicin
rpoA 3878893 c.-388_-386delCACinsAAG upstream_gene_variant 0.79 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 0.79 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.79 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.81 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.81 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.81 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.78 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.8 rifampicin Uncertain significance
clpC1 4038347 c.2358G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038353 c.2352G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038410 c.2295C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038416 c.2289C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038584 c.2121G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.91 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.88 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.88 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.88 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.88 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.88 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.92 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.91 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.9 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.9 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.91 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.93 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.92 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.94 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.94 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039238 c.1467C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039319 p.Ala462Gly missense_variant 0.91 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.91 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.93 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.93 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039592 c.1113G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039610 c.1095G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039691 c.1014G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039733 c.972G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039754 c.951G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039814 c.891C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.92 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.92 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.92 pyrazinamide
clpC1 4039840 c.865C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 0.96 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.98 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.94 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040123 c.582G>A synonymous_variant 0.92 pyrazinamide
clpC1 4040126 c.579C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040195 c.510G>C synonymous_variant 0.7 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.87 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 0.89 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>A synonymous_variant 0.91 pyrazinamide
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.91 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040303 c.402G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040306 c.399G>T synonymous_variant 0.95 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040318 c.387C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040342 c.363C>G synonymous_variant 0.98 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.95 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040441 c.264C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.89 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.89 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>T synonymous_variant 0.95 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040495 c.210C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040501 c.204C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.91 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.73 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.67 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.64 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.88 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.91 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040690 c.15T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.83 pyrazinamide
clpC1 4040696 c.9A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.77 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.83 pyrazinamide
panD 4044965 c.-684T>C upstream_gene_variant 0.82 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.82 pyrazinamide
panD 4044983 c.-702G>C upstream_gene_variant 0.82 pyrazinamide
panD 4044986 c.-705C>G upstream_gene_variant 0.82 pyrazinamide
panD 4044989 c.-708T>G upstream_gene_variant 0.82 pyrazinamide
panD 4044995 c.-714A>G upstream_gene_variant 0.83 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.91 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.91 pyrazinamide
panD 4045025 c.-744C>G upstream_gene_variant 0.91 pyrazinamide
panD 4045033 c.-752T>G upstream_gene_variant 0.91 pyrazinamide
panD 4045034 c.-753A>T upstream_gene_variant 0.91 pyrazinamide
panD 4045040 c.-759G>T upstream_gene_variant 0.91 pyrazinamide
glpK 4138661 c.1095T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138696 p.Pro354Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138697 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138703 c.1051_1053delCGCinsAGG synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138724 c.1032A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138775 c.981C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138796 c.960A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138799 c.957T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138802 c.954G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138808 c.948G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138817 p.Ala313Ser missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138822 p.Asn312Asp missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138823 c.933G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138829 c.927A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138847 c.909A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139585 c.171G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139594 c.162C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139601 p.Arg52Gln missense_variant 0.94 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139617 p.Glu47Gln missense_variant 0.95 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139630 c.126C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139637 p.Ala40Gly missense_variant 0.95 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139652 p.His35Ala missense_variant 0.94 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139654 c.102C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139672 c.84C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4239486 c.-377T>C upstream_gene_variant 0.8 ethambutol
embC 4239524 c.-339C>T upstream_gene_variant 0.92 ethambutol
embC 4239526 c.-337_-336delGGinsAC upstream_gene_variant 0.92 ethambutol
embC 4239530 c.-333C>G upstream_gene_variant 0.92 ethambutol
embC 4239533 c.-330T>C upstream_gene_variant 0.92 ethambutol
embC 4239539 c.-324G>C upstream_gene_variant 0.92 ethambutol
embC 4239540 c.-323T>C upstream_gene_variant 0.92 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.92 ethambutol
embC 4239569 c.-294A>C upstream_gene_variant 0.92 ethambutol
embC 4239570 c.-293C>G upstream_gene_variant 0.91 ethambutol
embC 4240702 c.840G>C synonymous_variant 0.85 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.93 ethambutol
embC 4240736 p.Ser292Ala missense_variant 1.0 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.98 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.98 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.98 ethambutol
embC 4240819 c.957A>T synonymous_variant 0.93 ethambutol
embC 4240825 c.963G>A synonymous_variant 0.91 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.9 ethambutol
embB 4247440 c.927C>G synonymous_variant 1.0 ethambutol
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247494 c.981G>A synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 1.0 ethambutol
embB 4247527 c.1014G>C synonymous_variant 1.0 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247555 p.Leu348Ile missense_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Ile missense_variant 1.0 ethambutol
embB 4247582 p.Ala357Cys missense_variant 1.0 ethambutol
embB 4247586 p.Gly358Ala missense_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247611 c.1098G>C synonymous_variant 1.0 ethambutol
embB 4248127 c.1614G>C synonymous_variant 0.91 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.91 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.92 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.93 ethambutol
embB 4248143 p.Leu544Met missense_variant 0.94 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 1.0 ethambutol
embB 4248167 p.Thr552Ala missense_variant 1.0 ethambutol
embB 4248170 p.Ala553Ser missense_variant 1.0 ethambutol
embB 4248173 p.Val554Leu missense_variant 1.0 ethambutol
embB 4248199 c.1686A>G synonymous_variant 1.0 ethambutol
embB 4248200 p.Ile563Val missense_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 1.0 ethambutol Uncertain significance
embB 4248242 p.Val577Ile missense_variant 0.96 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.95 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.95 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.94 ethambutol
embB 4248307 c.1794G>C synonymous_variant 0.92 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>T synonymous_variant 1.0 ethambutol
embB 4249480 c.2967G>T synonymous_variant 0.73 ethambutol
embB 4249483 c.2970C>G synonymous_variant 0.73 ethambutol
embB 4249486 c.2973T>A synonymous_variant 0.73 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.73 ethambutol