TB-Profiler result

Run: SRR25827682

Summary

Run ID: SRR25827682

Sample name:

Date: 2024-05-22T16:45:40.604251

Number of reads: 2223225

Percentage reads mapped: 52.23

Median coverage: 52.0

Strain:

Spoligotype:

Drug-resistance: Other


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.7.1 M.bovis None 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2224_2226delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 0.4 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.73 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305154 c.2224_2226delTTGinsCA frameshift_variant&missense_variant 0.29 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.59 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.76 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.46 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.55 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.6 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1014 c.1014C>G synonymous_variant 0.28 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.26 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.35 isoniazid
dnaA 1041 c.1041G>A synonymous_variant 0.41 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.43 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.49 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.47 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.46 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.46 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.46 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.46 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.45 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.45 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.46 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.42 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.41 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.38 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.38 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.38 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.38 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.32 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.26 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.42 levofloxacin Uncertain significance
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.36 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.32 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8198 c.897T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.56 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.67 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9278 c.1977G>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 0.74 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9389 c.2088C>T synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 9428 c.2127C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Tyr missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9452 c.2151G>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9458 c.2157A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9467 c.2166T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13852 c.-296_-294delTTAinsCG upstream_gene_variant 0.33 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 0.32 isoniazid
Rv0010c 13864 c.-306A>G upstream_gene_variant 0.32 isoniazid
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.36 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.36 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.39 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.39 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.38 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.38 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.41 isoniazid
fgd1 491106 c.324T>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491130 c.348C>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 0.37 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491607 c.825G>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>A synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 491718 c.936A>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491721 c.939A>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491724 c.942A>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fgd1 491727 c.945T>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 0.27 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
ccsA 619507 c.-384A>G upstream_gene_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 619528 c.-363C>G upstream_gene_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGCG upstream_gene_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.76 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 619584 c.-307A>T upstream_gene_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 619609 c.-282G>C upstream_gene_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.42 capreomycin
amikacin
kanamycin
ccsA 619705 c.-186G>C upstream_gene_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620226 c.336G>A synonymous_variant 0.49 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620265 c.375C>G synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620268 c.378G>C synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620284 c.394_396delGCGinsCC frameshift_variant&missense_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620298 c.408G>C synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.66 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.64 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.64 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>G synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>C synonymous_variant 0.36 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620569 c.679_681delGGAinsCC frameshift_variant&missense_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 620586 c.696C>G synonymous_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620601 c.711C>T synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>C synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 0.49 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620682 c.792G>A synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620688 c.798G>C synonymous_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAA frameshift_variant&missense_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.59 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.56 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.53 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.51 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 0.49 capreomycin
amikacin
kanamycin
ccsA 620790 c.900C>T synonymous_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620823 c.933C>T synonymous_variant 0.31 capreomycin
amikacin
kanamycin
Rv0565c 656156 p.Gln439Lys missense_variant 0.21 ethionamide
Rv0565c 656157 c.1314T>C synonymous_variant 0.25 ethionamide
Rv0565c 656166 c.1305C>G synonymous_variant 0.48 ethionamide
Rv0565c 656172 c.1299A>G synonymous_variant 0.49 ethionamide
Rv0565c 656179 p.Asp431Thr missense_variant 0.54 ethionamide
Rv0565c 656192 p.Asp427Asn missense_variant 0.6 ethionamide Uncertain significance
Rv0565c 656196 p.Leu425Arg missense_variant 0.61 ethionamide
Rv0565c 656219 p.His418Tyr missense_variant 0.64 ethionamide
Rv0565c 656220 c.1251A>C synonymous_variant 0.64 ethionamide
Rv0565c 656223 c.1248T>C synonymous_variant 0.64 ethionamide Not assoc w R - Interim
Rv0565c 656226 c.1243_1245delGCCinsTT frameshift_variant&missense_variant 0.65 ethionamide Uncertain significance
Rv0565c 656238 p.Ala411Glu missense_variant 0.65 ethionamide
Rv0565c 656243 p.Leu410Met missense_variant 0.65 ethionamide
Rv0565c 656244 c.1227A>C synonymous_variant 0.64 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.64 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.65 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.62 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.62 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.62 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.62 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.56 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.47 ethionamide Not assoc w R - Interim
Rv0565c 656361 c.1110C>G synonymous_variant 0.47 ethionamide
Rv0565c 656364 c.1107T>C synonymous_variant 0.48 ethionamide
Rv0565c 656367 c.1101_1104delTCGGinsGC frameshift_variant&synonymous_variant 0.48 ethionamide Uncertain significance
Rv0565c 656371 p.Pro367His missense_variant 0.46 ethionamide
Rv0565c 656375 c.1095_1096insAA frameshift_variant 0.48 ethionamide Uncertain significance
Rv0565c 656383 p.Val363Asn missense_variant 0.51 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.54 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.54 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.56 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.58 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.6 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.59 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.56 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.58 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.56 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.55 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.54 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.5 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.52 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.52 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.53 ethionamide Not assoc w R - Interim
Rv0565c 656526 p.Glu315Asp missense_variant 0.5 ethionamide
Rv0565c 656535 c.936C>G synonymous_variant 0.46 ethionamide
Rv0565c 656539 p.Ser311Ala missense_variant 0.48 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 0.49 ethionamide
Rv0565c 656550 c.919_921delAACinsGG frameshift_variant&missense_variant 0.45 ethionamide Uncertain significance
Rv0565c 656568 c.903G>C synonymous_variant 0.35 ethionamide
Rv0565c 656901 c.570C>G synonymous_variant 0.36 ethionamide
Rv0565c 656904 c.567G>C synonymous_variant 0.38 ethionamide
Rv0565c 656924 p.Ile183Val missense_variant 0.49 ethionamide
Rv0565c 656936 p.Thr179Ala missense_variant 0.48 ethionamide
Rv0565c 656940 c.531C>T synonymous_variant 0.44 ethionamide Not assoc w R - Interim
Rv0565c 656946 c.525T>C synonymous_variant 0.41 ethionamide
Rv0565c 656952 c.519A>C synonymous_variant 0.38 ethionamide Not assoc w R - Interim
Rv0565c 656967 c.504T>C synonymous_variant 0.42 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 0.42 ethionamide
Rv0565c 656978 p.Ala165Thr missense_variant 0.44 ethionamide
Rv0565c 656982 p.Gly163Gln missense_variant 0.44 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 0.43 ethionamide
Rv0565c 656990 p.Lys161Glu missense_variant 0.44 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 0.44 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 0.44 ethionamide
Rv0565c 657138 c.331_333delGCAinsTG frameshift_variant&missense_variant 0.33 ethionamide Uncertain significance
Rv0565c 657144 c.327T>G synonymous_variant 0.37 ethionamide
Rv0565c 657155 p.Asn106Asp missense_variant 0.44 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 0.45 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.52 ethionamide
Rv0565c 657187 p.His95Arg missense_variant 0.48 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.49 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.49 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.49 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.49 ethionamide Uncertain significance
Rv0565c 657201 c.270C>G synonymous_variant 0.5 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.61 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.67 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.67 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.71 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.72 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.73 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.73 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.72 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.68 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.67 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.67 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.7 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.7 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.68 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.67 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.67 ethionamide
Rv0565c 657372 c.99G>C synonymous_variant 0.58 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.57 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.5 ethionamide
Rv0565c 657399 c.72G>C synonymous_variant 0.39 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 0.35 ethionamide
Rv0565c 657405 c.64_66delCTGinsAT frameshift_variant&missense_variant 0.35 ethionamide Uncertain significance
Rv0565c 657408 c.63A>C synonymous_variant 0.35 ethionamide
Rv0565c 657423 c.48C>A synonymous_variant 0.21 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.34 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.34 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.44 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.45 ethionamide
Rv0565c 657680 c.-210G>C upstream_gene_variant 0.49 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.5 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.55 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.7 ethionamide
hadA 731682 c.-248C>G upstream_gene_variant 0.62 isoniazid
hadA 731687 c.-243_-242insCACAGATCTTTT upstream_gene_variant 0.62 isoniazid
hadA 731693 c.-237C>A upstream_gene_variant 0.62 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.63 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 0.62 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.62 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.63 isoniazid
hadA 731717 c.-213T>G upstream_gene_variant 0.67 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.72 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.75 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.61 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.48 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.45 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.4 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.38 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.38 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.37 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.37 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.36 isoniazid
hadA 731864 c.-66C>T upstream_gene_variant 0.24 isoniazid
hadA 732229 c.300C>G synonymous_variant 0.28 isoniazid Not assoc w R - Interim
hadA 732238 c.309G>C synonymous_variant 0.33 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.4 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.41 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.4 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.4 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.41 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.54 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.56 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.57 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.64 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.68 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.71 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.68 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.65 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.64 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 0.44 rifampicin Uncertain significance
nusG 734093 c.-161A>C upstream_gene_variant 0.42 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.43 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.42 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.42 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.42 rifampicin Uncertain significance
nusG 734123 c.-131C>G upstream_gene_variant 0.41 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.42 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.42 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.42 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 0.42 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.46 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.51 rifampicin
nusG 734175 c.-79_-77delGGTinsCTG upstream_gene_variant 0.52 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 0.55 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 0.52 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.53 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 0.5 rifampicin
nusG 734247 c.-7_-6delGAinsC upstream_gene_variant 0.25 rifampicin
nusG 734250 c.-4A>C upstream_gene_variant 0.24 rifampicin
nusG 734261 p.Thr3Ser missense_variant 0.25 rifampicin
nusG 734275 p.Thr8Pro missense_variant 0.26 rifampicin
nusG 734360 p.Ala36Val missense_variant 0.25 rifampicin Uncertain significance
nusG 734364 c.111G>C synonymous_variant 0.28 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.33 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.37 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.52 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.59 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.6 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.62 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.61 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.6 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.61 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.42 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.39 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.28 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.27 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.27 rifampicin
rpoB 760046 c.240G>C synonymous_variant 0.25 rifampicin
rpoB 760060 p.Tyr85Leu missense_variant 0.32 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.33 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.34 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.54 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.56 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.59 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.69 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.77 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.77 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.79 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.79 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.84 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.83 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.83 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.83 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.84 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.65 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.58 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.56 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.56 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.5 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.33 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.38 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.54 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.73 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.72 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.73 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.83 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.81 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.75 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.72 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.77 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.79 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.76 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.75 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.7 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.67 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.65 rifampicin
rpoB 761373 p.Val523His missense_variant 0.63 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.44 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.31 rifampicin
rpoB 761465 c.1659G>C synonymous_variant 0.26 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.4 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.51 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.57 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.69 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.69 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.58 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.5 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.33 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.35 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.33 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.32 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.33 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.33 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.33 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.33 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.38 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.45 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.46 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.47 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.47 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.46 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.46 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.68 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.67 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.63 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.59 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.6 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.69 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.73 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.72 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.71 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.72 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.77 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.8 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.78 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.75 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.75 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.76 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.75 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.74 rifampicin
rpoB 762413 c.2607G>A synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.75 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.78 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.79 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.72 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.73 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.72 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.71 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.68 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.66 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.66 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.66 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.44 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.45 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 0.36 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 0.38 rifampicin
rpoB 762744 p.Gln980Ala missense_variant 0.37 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.4 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 0.45 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.6 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.6 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.59 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.6 rifampicin Uncertain significance
rpoB 762810 c.3004_3006delGCCinsTG frameshift_variant&missense_variant 0.58 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.61 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.84 rifampicin
rpoC 763013 c.-357C>G upstream_gene_variant 0.85 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.8 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.82 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.75 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.71 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.7 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.69 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.71 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.65 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.65 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.51 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.66 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.69 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.76 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.8 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.65 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.82 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.82 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.81 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.82 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.8 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.81 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.78 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.76 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.78 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.77 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.75 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.74 rifampicin
rpoC 763877 c.508_510delCTAinsTG frameshift_variant&stop_gained 0.74 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.76 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.77 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.78 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 0.8 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.8 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.79 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.79 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.8 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.8 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.78 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.75 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.76 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.78 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.8 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.78 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.78 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.77 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.81 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.81 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.81 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.81 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.81 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.82 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.82 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.79 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.73 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.73 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.78 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.8 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.8 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.81 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.87 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.91 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.92 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.9 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.9 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.84 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.84 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.78 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.82 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.8 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.78 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.76 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.74 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.69 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.63 rifampicin
rpoC 765146 p.Pro593Asp missense_variant 0.25 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 0.27 rifampicin
rpoC 765233 p.Ala622Ser missense_variant 0.27 rifampicin
rpoC 765241 c.1872C>T synonymous_variant 0.27 rifampicin
rpoC 765244 c.1875T>C synonymous_variant 0.26 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 0.27 rifampicin
rpoC 765292 c.1923G>C synonymous_variant 0.61 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 0.62 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.63 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.65 rifampicin Uncertain significance
rpoC 765329 p.Ser654Gly missense_variant 0.66 rifampicin
rpoC 765346 c.1977C>G synonymous_variant 0.71 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.73 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.78 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.79 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.82 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.8 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.77 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.78 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.78 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.77 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.76 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.79 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.77 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.77 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.79 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.79 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.79 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.78 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.79 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.82 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.82 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.83 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.82 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.83 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.83 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.84 rifampicin
rpoC 766036 c.2667C>T synonymous_variant 0.84 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.82 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.81 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.79 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.79 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.71 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.65 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766168 c.2799C>T synonymous_variant 0.6 rifampicin
rpoC 766174 p.Asn935Lys missense_variant 0.57 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.53 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.48 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 766192 c.2823T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 0.46 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 0.44 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.44 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 766219 p.Asp950Glu missense_variant 0.42 rifampicin
rpoC 766222 c.2853T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857T>C synonymous_variant 0.42 rifampicin
rpoC 766231 c.2862T>G synonymous_variant 0.42 rifampicin
rpoC 766234 c.2865T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 766237 c.2868T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 0.41 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 0.41 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 0.5 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.48 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.47 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.51 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.53 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.6 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.68 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.7 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.7 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.72 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.75 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.75 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.77 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.78 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.82 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.8 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.77 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.74 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.74 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.77 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.77 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.77 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.76 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.78 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.78 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.76 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.74 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.73 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.73 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.73 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.74 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.75 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.75 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.74 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.74 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.8 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.8 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.85 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.84 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.85 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.84 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.84 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.85 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.83 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.83 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.82 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.84 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.81 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.74 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.67 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.5 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.52 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.52 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.55 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 775901 c.2580G>A synonymous_variant 0.25 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.28 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 0.28 clofazimine
bedaquiline
mmpL5 775916 c.2565T>C synonymous_variant 0.29 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.29 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.29 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.29 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.28 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.23 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.25 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.25 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 0.26 clofazimine
bedaquiline
mmpL5 776030 c.2451G>A synonymous_variant 0.27 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.55 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.64 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.61 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.62 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.66 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.65 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.68 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.69 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.74 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.71 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.71 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.7 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.67 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.68 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.69 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.71 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.73 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.74 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.74 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.78 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.78 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.8 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.8 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.78 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.77 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.76 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.76 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.76 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.71 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.7 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.65 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.6 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.67 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.69 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.7 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.74 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.78 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.78 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.82 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.84 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.84 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.83 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.82 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.82 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.83 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.83 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.83 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.84 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.83 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.82 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.81 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.82 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.83 linezolid
rplC 800814 c.6A>G synonymous_variant 0.82 linezolid
rplC 800817 c.9A>T synonymous_variant 0.82 linezolid
rplC 800844 c.36T>C synonymous_variant 0.81 linezolid
rplC 800865 c.57A>G synonymous_variant 0.76 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.75 linezolid
rplC 800874 c.66A>G synonymous_variant 0.72 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 0.72 linezolid
rplC 800880 c.72A>G synonymous_variant 0.71 linezolid
rplC 800889 c.81C>G synonymous_variant 0.7 linezolid
rplC 800892 c.84G>C synonymous_variant 0.69 linezolid
rplC 800907 c.99C>G synonymous_variant 0.67 linezolid
rplC 800916 c.108A>G synonymous_variant 0.63 linezolid
rplC 800934 c.126C>G synonymous_variant 0.54 linezolid
rplC 800937 c.129A>G synonymous_variant 0.53 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.53 linezolid
rplC 800946 c.138T>C synonymous_variant 0.53 linezolid
rplC 800949 c.141T>C synonymous_variant 0.53 linezolid
rplC 800967 c.159C>G synonymous_variant 0.46 linezolid
rplC 800970 c.162T>C synonymous_variant 0.44 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.3 linezolid
rplC 800985 c.177A>G synonymous_variant 0.28 linezolid
rplC 801246 c.438C>T synonymous_variant 0.27 linezolid
rplC 801249 c.441T>C synonymous_variant 0.27 linezolid
rplC 801255 c.447C>T synonymous_variant 0.27 linezolid
rplC 801264 c.456C>T synonymous_variant 0.25 linezolid
rplC 801267 c.459A>T synonymous_variant 0.26 linezolid
rplC 801270 c.462T>C synonymous_variant 0.25 linezolid
rplC 801276 c.468G>C synonymous_variant 0.28 linezolid
rplC 801285 c.477G>C synonymous_variant 0.3 linezolid
rplC 801300 c.492C>G synonymous_variant 0.43 linezolid
rplC 801309 c.501C>G synonymous_variant 0.53 linezolid
rplC 801312 c.504G>C synonymous_variant 0.51 linezolid
rplC 801321 c.513C>T synonymous_variant 0.56 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.59 linezolid
rplC 801339 c.531T>C synonymous_variant 0.55 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.55 linezolid
rplC 801348 c.540T>G synonymous_variant 0.55 linezolid
rplC 801357 c.549T>C synonymous_variant 0.55 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.54 linezolid
rplC 801402 c.594T>C synonymous_variant 0.63 linezolid
rplC 801405 c.597T>C synonymous_variant 0.63 linezolid
rplC 801423 c.615G>C synonymous_variant 0.69 linezolid
rplC 801426 c.618C>G synonymous_variant 0.71 linezolid
rplC 801427 p.Met207Val missense_variant 0.71 linezolid
rplC 801438 c.630T>C synonymous_variant 0.75 linezolid
rplC 801442 p.Ile212Val missense_variant 0.73 linezolid
fbiC 1303512 c.582T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1303650 c.720G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303654 c.724C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303663 c.733C>T synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303668 c.738C>T synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1303671 c.741C>T synonymous_variant 0.43 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.64 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304535 c.1605G>A synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.47 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1305201 c.2271G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>A synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305234 c.2304G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 0.5 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1305279 p.His783Gln missense_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1305300 c.2370A>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305303 c.2373T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305309 c.2379G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1305318 c.2388C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1305372 c.2442G>A synonymous_variant 0.49 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305384 c.2454G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 0.4 clofazimine Not assoc w R - Interim
pretomanid
delamanid
sigE 1364793 c.381C>T synonymous_variant 0.21 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.29 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.31 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.4 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.4 pyrazinamide
sigE 1364839 c.427_429delTTGinsCC frameshift_variant&missense_variant 0.38 pyrazinamide Uncertain significance
sigE 1364847 c.435G>C synonymous_variant 0.36 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.38 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.37 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.37 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.37 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.35 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 0.35 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.34 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.34 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.25 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
sigE 1365006 c.594T>C synonymous_variant 0.29 pyrazinamide
sigE 1365009 c.597C>G synonymous_variant 0.29 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.3 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.3 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.3 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.31 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.32 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.32 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.33 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.33 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.35 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.34 pyrazinamide
sigE 1365087 c.675A>C synonymous_variant 0.35 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.34 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 0.33 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.33 pyrazinamide
sigE 1365114 c.702G>A synonymous_variant 0.33 pyrazinamide
sigE 1365117 c.705A>C synonymous_variant 0.33 pyrazinamide
sigE 1365118 c.706C>T synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
atpE 1460816 c.-229T>C upstream_gene_variant 0.4 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.39 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.36 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.36 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.35 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.37 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.36 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.33 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.29 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.28 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.28 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 0.27 bedaquiline
atpE 1460918 c.-127A>G upstream_gene_variant 0.26 bedaquiline
atpE 1461089 c.45G>C synonymous_variant 0.45 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 0.51 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.52 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.58 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 0.6 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.68 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.71 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.71 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.72 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.71 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.72 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.72 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.74 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.74 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.7 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.62 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.59 bedaquiline
atpE 1461275 c.231T>A synonymous_variant 0.37 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.56 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
fabG1 1673890 p.Ala151Ser missense_variant 0.27 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.27 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.27 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.27 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.27 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.27 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.35 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.42 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.44 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 0.52 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.52 ethionamide
isoniazid
inhA 1674015 c.-187C>T upstream_gene_variant 0.51 ethionamide
isoniazid Uncertain significance
inhA 1674018 c.-184G>C upstream_gene_variant 0.49 ethionamide
isoniazid
inhA 1674021 c.-181G>C upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.49 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.49 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.49 ethionamide
isoniazid
inhA 1674042 c.-160G>T upstream_gene_variant 0.48 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGC frameshift_variant&missense_variant 0.48 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.48 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.47 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.47 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.42 ethionamide
isoniazid
inhA 1674114 c.-88T>A upstream_gene_variant 0.24 ethionamide Uncertain significance
isoniazid Uncertain significance
rpsA 1833515 c.-27_-24delCAACinsAAA upstream_gene_variant 0.3 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.55 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.64 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.72 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.75 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.85 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.82 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.81 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.82 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.8 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.82 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.83 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.82 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.83 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.82 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.79 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.79 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.7 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.7 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.72 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.75 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.58 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.51 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.54 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.63 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.29 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.36 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.46 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.43 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.43 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.33 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.26 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.66 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.65 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.63 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.61 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.6 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.55 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.56 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.49 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.38 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.35 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.33 linezolid
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2063349 c.1380G>A synonymous_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064870 c.-142A>G upstream_gene_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064873 c.-145A>T upstream_gene_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064882 c.-154C>G upstream_gene_variant 0.42 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064892 c.-164A>G upstream_gene_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064897 c.-169C>G upstream_gene_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064903 c.-175G>A upstream_gene_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064912 c.-184A>G upstream_gene_variant 0.52 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064915 c.-187G>C upstream_gene_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064933 c.-205A>G upstream_gene_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.63 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
ndh 2102131 c.910_912delCAAinsAG frameshift_variant&synonymous_variant 0.28 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102140 c.903C>T synonymous_variant 0.27 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102155 c.888G>A synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102158 c.885T>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102162 p.Arg294Thr missense_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102164 c.879A>G synonymous_variant 0.26 ethionamide
delamanid
isoniazid
ndh 2102167 c.876A>G synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102170 p.Glu291Asp missense_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102176 c.867T>C synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2102182 c.859_861delAGGinsCC frameshift_variant&missense_variant 0.27 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102190 c.853T>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102192 p.Arg284Pro missense_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102194 c.849T>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102206 c.837G>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102212 c.831G>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>A synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>T synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.25 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102302 c.741G>C synonymous_variant 0.26 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102314 c.729C>T synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 0.26 ethionamide
delamanid
isoniazid
ndh 2102332 c.709_711delCAGinsGA frameshift_variant&missense_variant 0.25 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102337 c.706T>C synonymous_variant 0.26 ethionamide Not assoc w R - Interim
delamanid
isoniazid
ndh 2102342 p.Ala234Asp missense_variant 0.26 ethionamide
delamanid
isoniazid
ndh 2102356 c.687T>C synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102366 p.Ala226Glu missense_variant 0.25 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102368 c.675C>T synonymous_variant 0.23 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102373 p.Met224Leu missense_variant 0.24 ethionamide
delamanid
isoniazid
ndh 2102407 c.636T>C synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102413 c.630G>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
katG 2155632 c.480A>C synonymous_variant 0.29 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.32 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.43 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.54 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.53 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.56 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.57 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.6 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.6 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.62 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.6 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.6 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.6 isoniazid
katG 2155782 c.330C>G synonymous_variant 0.42 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.43 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
Rv1979c 2223491 c.-327C>A upstream_gene_variant 0.98 clofazimine Not assoc w R
bedaquiline Uncertain significance
pncA 2289045 p.Ser66Leu missense_variant 1.0 pyrazinamide Not assoc w R - Interim
kasA 2517950 c.-165C>G upstream_gene_variant 0.75 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.61 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.6 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.47 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.42 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.25 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.33 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.31 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.28 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.25 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.22 isoniazid
kasA 2518421 p.Val103Leu missense_variant 0.23 isoniazid
kasA 2518439 p.Ala109Ser missense_variant 0.24 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.25 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.26 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.29 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.28 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.28 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.3 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.29 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.32 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.31 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.32 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.26 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.36 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.47 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.53 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.57 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.61 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.58 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.58 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.57 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.6 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.61 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.61 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.66 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.72 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.71 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.71 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.7 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.7 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.69 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.67 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.67 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.6 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.5 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.38 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.33 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.24 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.24 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.27 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.29 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 0.28 isoniazid
kasA 2519218 c.1104G>A synonymous_variant 0.28 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.29 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 0.27 isoniazid
kasA 2519230 c.1116C>T synonymous_variant 0.26 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 0.25 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.25 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 0.26 isoniazid
kasA 2519260 c.1146T>G synonymous_variant 0.26 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 0.25 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 0.25 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 0.25 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.24 isoniazid
folC 2746308 p.Arg431Ser missense_variant 0.33 para-aminosalicylic_acid
folC 2746321 c.1278A>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746328 p.Arg424Thr missense_variant 0.32 para-aminosalicylic_acid
folC 2746335 p.Gly422Arg missense_variant 0.3 para-aminosalicylic_acid
folC 2746336 c.1263C>G synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746345 c.1254G>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746351 c.1246_1248delGCCinsTG frameshift_variant&missense_variant 0.33 para-aminosalicylic_acid
folC 2746354 c.1245G>A synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746360 c.1239T>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746363 c.1234_1236delCTGinsGC frameshift_variant&missense_variant 0.34 para-aminosalicylic_acid
folC 2746375 c.1224G>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746390 c.1207_1209delGTGinsAC frameshift_variant&missense_variant 0.35 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.36 para-aminosalicylic_acid
folC 2746401 p.Ser400Ala missense_variant 0.33 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746414 c.1183_1185delGAGinsCA frameshift_variant&missense_variant 0.33 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.34 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.38 para-aminosalicylic_acid
folC 2746471 c.1128C>A synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746478 p.Phe374Tyr missense_variant 0.4 para-aminosalicylic_acid
folC 2746480 c.1119A>C synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746492 c.1107G>A synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746495 p.His368Gly missense_variant 0.41 para-aminosalicylic_acid
folC 2746507 c.1092A>G synonymous_variant 0.37 para-aminosalicylic_acid
folC 2746510 c.1089A>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746516 c.1083T>G synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746519 p.Ser360Ala missense_variant 0.39 para-aminosalicylic_acid
folC 2746522 c.1077G>C synonymous_variant 0.38 para-aminosalicylic_acid
folC 2746525 c.1074G>T synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746531 c.1068G>C synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746534 c.1065T>C synonymous_variant 0.44 para-aminosalicylic_acid
folC 2746558 c.1041G>T synonymous_variant 0.42 para-aminosalicylic_acid
folC 2746564 c.1035A>G synonymous_variant 0.42 para-aminosalicylic_acid
folC 2746576 c.1023C>G synonymous_variant 0.36 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2747021 p.Val193Ala missense_variant 0.29 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.27 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.27 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.25 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.31 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.33 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.32 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747410 c.187_188delAG frameshift_variant 0.3 para-aminosalicylic_acid
folC 2747415 c.184delCinsTTG frameshift_variant&missense_variant 0.31 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747422 c.177G>A synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747425 c.174C>T synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.33 para-aminosalicylic_acid
Rv2477c 2783140 c.903C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.54 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.57 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.55 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783497 c.544_546delTTGinsCC frameshift_variant&missense_variant 0.32 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.34 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>A synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.73 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.68 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.59 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784589 c.-547A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859765 c.654G>C synonymous_variant 0.3 clofazimine
bedaquiline
pepQ 2859774 c.645C>T synonymous_variant 0.3 clofazimine
bedaquiline
pepQ 2859778 p.Val214Ala missense_variant 0.3 clofazimine
bedaquiline
pepQ 2859781 p.Gln213Ala missense_variant 0.3 clofazimine
bedaquiline
pepQ 2859787 p.Val211Ala missense_variant 0.31 clofazimine
bedaquiline
pepQ 2859789 c.630G>C synonymous_variant 0.31 clofazimine
bedaquiline
pepQ 2859798 c.621G>C synonymous_variant 0.3 clofazimine
bedaquiline
pepQ 2859801 c.618G>C synonymous_variant 0.31 clofazimine
bedaquiline
pepQ 2859804 c.615C>T synonymous_variant 0.31 clofazimine
bedaquiline
pepQ 2859807 c.612C>T synonymous_variant 0.31 clofazimine
bedaquiline
Rv2752c 3064887 c.1305A>G synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064893 c.1299C>G synonymous_variant 0.48 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064896 c.1296T>C synonymous_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>G synonymous_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064926 c.1264_1266delTTGinsCC frameshift_variant&missense_variant 0.54 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064932 c.1260T>C synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064935 c.1257A>G synonymous_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 0.5 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064956 c.1234_1236delAGTinsCC frameshift_variant&missense_variant 0.55 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064962 c.1230C>G synonymous_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064973 p.Ala407Ser missense_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065028 c.1162_1164delGTGinsAC frameshift_variant&missense_variant 0.63 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065040 c.1152C>G synonymous_variant 0.66 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 0.56 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065082 c.1110G>C synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 0.58 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 0.57 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065115 c.1077C>G synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065126 p.Ser356Ala missense_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065127 c.1065G>C synonymous_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 p.Ala354Glu missense_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065151 c.1041G>C synonymous_variant 0.63 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065183 p.Ser337Ala missense_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065190 c.1000_1002delATCinsGG frameshift_variant&missense_variant 0.4 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065196 c.996T>C synonymous_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>G synonymous_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>C synonymous_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065210 c.982T>C synonymous_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065223 c.969T>C synonymous_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065229 c.963G>C synonymous_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065262 c.930G>A synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065288 c.904T>C synonymous_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065292 c.900T>C synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065295 p.Gln299Arg missense_variant 0.49 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065298 p.Asp298Glu missense_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065306 p.Ala296Pro missense_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065311 p.Thr294Met missense_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065313 c.879A>G synonymous_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065323 p.Ala290Gly missense_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065334 c.856_858delCTCinsGG frameshift_variant&missense_variant 0.54 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065337 c.855T>C synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065346 c.846T>G synonymous_variant 0.55 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065352 c.840A>G synonymous_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065355 c.837A>G synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065364 c.828G>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065367 c.823_825delCAAinsGG frameshift_variant&missense_variant 0.46 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065372 c.820A>C synonymous_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065373 c.819A>C synonymous_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065378 p.Val272Ile missense_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065381 p.Arg271Gly missense_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065397 c.795G>C synonymous_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>C synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065544 c.648C>T synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 0.33 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065562 c.630T>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065569 p.Ile208His missense_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065586 c.606C>T synonymous_variant 0.37 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065598 c.594G>T synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065607 c.585C>G synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065612 p.Thr194Ala missense_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065616 c.576C>T synonymous_variant 0.26 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065622 c.570G>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065625 c.567G>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065646 c.546C>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065659 p.Pro178Leu missense_variant 0.27 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065664 c.526_528delTTGinsCT frameshift_variant&missense_variant 0.27 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065667 c.525A>G synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065676 c.516G>A synonymous_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065697 c.493_495delATCinsGT frameshift_variant&missense_variant 0.37 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065700 c.492C>G synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065715 c.475_477delTATinsCC frameshift_variant&missense_variant 0.32 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065721 c.471G>C synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065727 c.465C>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065732 c.460T>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065742 p.Thr150Ile missense_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065806 p.Arg129Ala missense_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065915 c.277C>T synonymous_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065925 p.Ala89Gly missense_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 0.43 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065946 p.Gly82Ala missense_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCC frameshift_variant&missense_variant 0.53 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 0.66 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.67 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066009 c.183G>C synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.7 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.66 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.66 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.66 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.66 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066150 c.42C>A synonymous_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066237 c.-46C>G upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066249 c.-58C>T upstream_gene_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066261 c.-70G>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066270 c.-79G>A upstream_gene_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066276 c.-85G>A upstream_gene_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066279 c.-88A>G upstream_gene_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066282 c.-91G>T upstream_gene_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066287 c.-96G>C upstream_gene_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066290 c.-99G>A upstream_gene_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066291 c.-100G>A upstream_gene_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066315 c.-124C>T upstream_gene_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.48 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066370 c.-180_-179delAGinsGC upstream_gene_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066396 c.-207_-205delGCGinsAC upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066399 c.-210_-208delATTinsTCC upstream_gene_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066435 c.-246_-244delGGTinsAAC upstream_gene_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066452 c.-261T>A upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066453 c.-262G>A upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066456 c.-265A>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066462 c.-271G>A upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-276_-274delGGGinsAAT upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066476 c.-285C>G upstream_gene_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066482 c.-291G>T upstream_gene_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>G upstream_gene_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066638 c.-447T>G upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066642 c.-453_-451delTTGinsCC upstream_gene_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066657 c.-466C>G upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066665 c.-474G>C upstream_gene_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066713 c.-522C>T upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066714 c.-524_-523delAGinsCA upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066734 c.-543G>A upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066744 c.-553C>G upstream_gene_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066747 c.-558_-556delCAAinsATC upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066756 c.-567_-565delCGGinsAC upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066762 c.-571G>C upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066855 c.-664T>C upstream_gene_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066864 c.-673C>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066891 c.-700G>C upstream_gene_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066900 c.-709A>G upstream_gene_variant 0.59 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066905 c.-714T>C upstream_gene_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066906 c.-715C>G upstream_gene_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066910 c.-719C>T upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066912 c.-721G>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066924 c.-735_-733delATCinsCGG upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066927 c.-736A>G upstream_gene_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066933 c.-743_-742delGGinsAC upstream_gene_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066960 c.-769C>G upstream_gene_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066969 c.-778G>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>G upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066987 c.-796C>T upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066990 c.-799G>T upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066994 c.-804_-803delCAinsGC upstream_gene_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066996 c.-805T>C upstream_gene_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067001 c.-810G>A upstream_gene_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067017 c.-827_-826delGGinsAC upstream_gene_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067020 c.-829G>C upstream_gene_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067023 c.-832G>C upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067038 c.-847G>C upstream_gene_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067047 c.-856T>C upstream_gene_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067052 c.-861G>C upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067055 c.-864A>C upstream_gene_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067065 c.-874G>C upstream_gene_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067223 c.723G>C synonymous_variant 0.49 para-aminosalicylic_acid
thyX 3067232 c.714C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067246 p.Thr234Ala missense_variant 0.58 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 0.57 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 0.57 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067281 p.Val222Ala missense_variant 0.65 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.66 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 0.66 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.66 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.66 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067328 c.618G>A synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.79 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.8 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.78 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.79 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.8 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.8 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.8 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.81 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.74 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.75 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.73 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067736 c.208_210delTTCinsCT frameshift_variant&missense_variant 0.71 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.76 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.76 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.7 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.65 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 0.52 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.26 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.32 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.32 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3073941 c.531C>T synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3073983 c.489C>T synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.36 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 0.36 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074372 p.Met34Leu missense_variant 0.27 para-aminosalicylic_acid
thyA 3074377 p.Gln32Arg missense_variant 0.29 para-aminosalicylic_acid
thyA 3074391 c.81C>A synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074397 c.75A>G synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3074412 c.60C>T synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3074423 p.Pro17Ala missense_variant 0.31 para-aminosalicylic_acid
thyA 3074427 c.45T>A synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3074431 p.Thr14Glu missense_variant 0.32 para-aminosalicylic_acid
thyA 3074433 p.Glu13Asp missense_variant 0.33 para-aminosalicylic_acid
thyA 3074442 c.28_30delTTCinsCG frameshift_variant&missense_variant 0.34 para-aminosalicylic_acid
thyA 3074445 c.27C>A synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074448 c.24G>T synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074463 c.9A>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074470 p.Val1Pro missense_variant 0.33 para-aminosalicylic_acid
thyA 3074477 c.-6T>C upstream_gene_variant 0.35 para-aminosalicylic_acid
thyA 3074490 c.-19G>A upstream_gene_variant 0.39 para-aminosalicylic_acid
ald 3087672 p.His285Asp missense_variant 0.24 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.26 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.3 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.3 cycloserine
ald 3087737 c.918G>C synonymous_variant 0.31 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.32 cycloserine
ald 3087750 p.Tyr311Val missense_variant 0.33 cycloserine
ald 3087761 c.942C>G synonymous_variant 0.32 cycloserine
ald 3087770 c.951G>C synonymous_variant 0.37 cycloserine
lpqB 3623512 p.Gly467Ser missense_variant 0.25 bedaquiline
rifampicin
lpqB 3623531 c.1380T>C synonymous_variant 0.36 bedaquiline
rifampicin
lpqB 3623549 c.1362C>G synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3623555 c.1354_1356delGGGinsAC frameshift_variant&missense_variant 0.35 bedaquiline
rifampicin Uncertain significance
lpqB 3623561 c.1350T>C synonymous_variant 0.36 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3623573 c.1336_1338delCTTinsTG frameshift_variant&synonymous_variant 0.37 bedaquiline
rifampicin Uncertain significance
lpqB 3623580 p.Asn444Thr missense_variant 0.39 bedaquiline
rifampicin
lpqB 3623587 p.Ala442Pro missense_variant 0.39 bedaquiline
rifampicin
lpqB 3623597 c.1314C>G synonymous_variant 0.39 bedaquiline
rifampicin
lpqB 3623601 p.Ser437Thr missense_variant 0.39 bedaquiline
rifampicin
lpqB 3623612 p.Thr433Val missense_variant 0.36 bedaquiline
rifampicin
lpqB 3623630 c.1281G>C synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 0.24 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 0.25 bedaquiline
rifampicin
lpqB 3624050 c.861C>G synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3624077 c.834G>A synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624082 c.829A>C synonymous_variant 0.42 bedaquiline
rifampicin
lpqB 3624086 c.825C>T synonymous_variant 0.4 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624092 c.817_819delAGGinsCC frameshift_variant&missense_variant 0.4 bedaquiline
rifampicin Uncertain significance
lpqB 3624100 c.811T>C synonymous_variant 0.38 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 0.38 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.41 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3624119 c.792C>G synonymous_variant 0.45 bedaquiline
rifampicin
lpqB 3624124 p.Leu263Val missense_variant 0.43 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3624143 c.768T>C synonymous_variant 0.55 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.46 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 0.45 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624173 c.738A>C synonymous_variant 0.46 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624179 c.732C>G synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3624185 c.726C>T synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624194 c.717C>G synonymous_variant 0.36 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 0.33 bedaquiline
rifampicin
lpqB 3624209 c.702A>C synonymous_variant 0.3 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.26 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.35 bedaquiline
rifampicin
lpqB 3625549 c.-639G>A upstream_gene_variant 0.37 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.44 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.45 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.49 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.49 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.48 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625636 c.978C>G synonymous_variant 0.51 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.49 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.48 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.43 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.4 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.39 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.41 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.39 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.38 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 0.42 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 0.42 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.45 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.46 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.46 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625797 p.Val273Met missense_variant 0.43 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.43 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.44 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.43 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 0.42 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.36 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 0.32 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626687 c.-74G>T upstream_gene_variant 0.39 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 0.58 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.68 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.69 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626912 c.-299T>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3627065 c.-452G>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627071 c.279G>T synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.73 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.62 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3627375 c.-762C>G upstream_gene_variant 0.42 bedaquiline
rifampicin
mtrB 3627377 c.-764G>C upstream_gene_variant 0.4 bedaquiline
rifampicin
mtrB 3627380 c.-767T>C upstream_gene_variant 0.39 bedaquiline
rifampicin
fbiB 3641840 c.306T>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiB 3641846 c.312G>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiB 3641852 c.318C>G synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiB 3641864 c.330A>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiB 3641876 c.342C>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3641879 c.345G>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3641880 p.Ser116Asp missense_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3641888 c.354A>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3641891 c.357G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3641900 c.366G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3641906 c.372T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiB 3641909 c.375T>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3641914 p.Ala127Gly missense_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3641918 c.384T>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3641924 c.390A>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiB 3641927 c.393C>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3641928 c.394T>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiB 3641938 p.Gly135Ala missense_variant 0.38 clofazimine
pretomanid
delamanid
fbiB 3641961 p.Thr143Glu missense_variant 0.34 clofazimine
pretomanid
delamanid
fbiB 3641972 c.438G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiB 3642560 c.1026T>C synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiB 3642566 c.1032A>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642587 p.Met351Ile missense_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>T synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642609 c.1075_1076delAGinsTC synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiB 3642614 c.1080C>T synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiB 3642617 c.1083C>G synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiB 3642731 c.1197C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3642758 c.1224C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3642763 p.Asp410Ala missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3642770 c.1236G>C synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiB 3642779 c.1245A>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiB 3642781 p.Val416Ala missense_variant 0.43 clofazimine
pretomanid
delamanid
fbiB 3642809 c.1275G>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
alr 3841010 c.411A>G synonymous_variant 0.25 cycloserine
alr 3841017 p.Leu135Glu missense_variant 0.27 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.24 cycloserine
alr 3841037 c.382_384delGTGinsAA frameshift_variant&missense_variant 0.26 cycloserine
alr 3841059 p.Gly121Ala missense_variant 0.26 cycloserine
alr 3841069 p.Ile118Phe missense_variant 0.27 cycloserine
alr 3841079 c.342T>C synonymous_variant 0.29 cycloserine
rpoA 3877482 c.1026C>G synonymous_variant 0.35 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 0.49 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.51 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.53 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.59 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.74 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.8 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.83 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.85 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.81 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.8 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.76 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.73 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.62 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877824 c.684G>A synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoA 3878376 c.132G>C synonymous_variant 0.55 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.57 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.56 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.59 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.62 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.64 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.64 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.64 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.58 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.57 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.57 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.57 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.54 rifampicin
rpoA 3878935 c.-428C>T upstream_gene_variant 0.27 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 0.29 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.37 rifampicin Uncertain significance
rpoA 3878953 c.-446C>T upstream_gene_variant 0.37 rifampicin
rpoA 3878956 c.-449G>T upstream_gene_variant 0.41 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 0.41 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.43 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGT upstream_gene_variant 0.98 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.51 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.51 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.59 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 0.66 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.72 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.71 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.71 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.75 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.73 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.74 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.75 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.71 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.7 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.66 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.63 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.61 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.62 rifampicin
clpC1 4038197 c.2508A>G synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4038200 c.2505T>C synonymous_variant 0.28 pyrazinamide
clpC1 4038212 c.2493T>C synonymous_variant 0.49 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.65 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 0.67 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.66 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 0.66 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.66 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.7 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.7 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.69 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.7 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.7 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.7 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.73 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.71 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.75 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.76 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.76 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.75 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.77 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.78 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.74 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.73 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.72 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.74 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.72 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.68 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.65 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.63 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.61 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.6 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.58 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.58 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.61 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.64 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.62 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.73 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.72 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.73 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.78 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.8 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.81 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.83 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.77 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.7 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.62 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.61 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.44 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.39 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.39 pyrazinamide
clpC1 4039217 c.1488G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.57 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.57 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.6 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.59 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.59 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.58 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.61 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.63 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.6 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.63 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.62 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.59 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.62 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.61 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.69 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.7 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.64 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039682 c.1023C>T synonymous_variant 0.61 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039700 c.1005C>T synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4039724 c.981A>G synonymous_variant 0.56 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.51 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.43 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.53 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.67 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.71 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.68 pyrazinamide
clpC1 4039994 c.711G>A synonymous_variant 0.69 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.66 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.68 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.52 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.56 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4040354 c.351A>G synonymous_variant 0.46 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.52 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.54 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.56 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.56 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.58 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.73 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.76 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.69 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.7 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 0.67 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.67 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.58 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.56 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.52 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.47 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.44 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.44 pyrazinamide
clpC1 4040596 c.109C>T synonymous_variant 0.42 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.42 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 0.42 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.42 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.4 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.25 pyrazinamide
panD 4043872 p.Gly137Val missense_variant 0.24 pyrazinamide Uncertain significance
panD 4043876 p.Leu136Ile missense_variant 0.24 pyrazinamide
panD 4043883 c.399C>T synonymous_variant 0.24 pyrazinamide
panD 4043896 p.Gly129Ala missense_variant 0.25 pyrazinamide
panD 4043961 c.321T>C synonymous_variant 0.24 pyrazinamide
panD 4043964 c.318G>C synonymous_variant 0.24 pyrazinamide
panD 4044688 c.-407T>C upstream_gene_variant 0.3 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 0.35 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 0.35 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 0.37 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.36 pyrazinamide
panD 4044716 c.-435G>A upstream_gene_variant 0.36 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.37 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.36 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.33 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.32 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.22 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.28 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.3 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.36 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.36 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.39 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.38 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.34 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.34 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.34 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.34 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.32 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 0.32 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.3 pyrazinamide
panD 4045105 c.-824T>C upstream_gene_variant 0.29 pyrazinamide
panD 4045112 c.-831A>G upstream_gene_variant 0.27 pyrazinamide
panD 4045115 c.-834G>C upstream_gene_variant 0.26 pyrazinamide
panD 4045125 c.-844T>A upstream_gene_variant 0.23 pyrazinamide
panD 4045127 c.-846A>C upstream_gene_variant 0.24 pyrazinamide
glpK 4138565 c.1191G>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>A synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>A synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.72 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.74 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>A synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138838 c.918G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138841 c.915G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138847 c.909A>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138853 c.903C>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138859 c.895_897delAATinsGC frameshift_variant&missense_variant 0.53 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138862 c.894G>C synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138865 c.891A>G synonymous_variant 0.48 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138877 c.879A>G synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138880 c.876T>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138892 c.864G>A synonymous_variant 0.37 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138898 c.858T>C synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138910 c.846G>C synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>C synonymous_variant 0.25 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139135 c.619_621delGATinsAC frameshift_variant&synonymous_variant 0.26 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139143 c.613T>C synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>G synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 0.3 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139195 c.561G>T synonymous_variant 0.29 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139198 c.558C>G synonymous_variant 0.3 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139207 c.549T>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139231 c.525A>C synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>G synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239111 c.-752G>A upstream_gene_variant 0.23 ethambutol
embC 4239140 c.-723G>C upstream_gene_variant 0.26 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.26 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.25 ethambutol Uncertain significance
embC 4239157 c.-706C>T upstream_gene_variant 0.23 ethambutol
embC 4239161 c.-702A>T upstream_gene_variant 0.24 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.27 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.32 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.34 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.54 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.56 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.59 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.67 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.66 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.69 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.59 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.59 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.6 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.57 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.57 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.56 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.54 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.52 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.51 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.52 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.48 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.48 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.41 ethambutol
embC 4240945 c.1083T>G synonymous_variant 0.34 ethambutol
embC 4241032 c.1170G>C synonymous_variant 0.25 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.28 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.29 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.29 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.3 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.32 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.32 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.35 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244611 p.Ala460Gly missense_variant 0.31 ethambutol
embA 4244616 p.Ala462Ser missense_variant 0.29 ethambutol
embA 4244619 c.1387_1389delTTGinsCC frameshift_variant&missense_variant 0.29 ethambutol Uncertain significance
embA 4244625 p.Leu465Val missense_variant 0.29 ethambutol
embA 4244631 p.Thr467Leu missense_variant 0.28 ethambutol
embA 4244645 c.1413T>C synonymous_variant 0.27 ethambutol
embA 4244648 c.1416G>C synonymous_variant 0.27 ethambutol
embA 4244649 p.Asp473Ser missense_variant 0.26 ethambutol
embA 4244670 p.Ala480Leu missense_variant 0.24 ethambutol
embA 4244702 c.1470C>G synonymous_variant 0.23 ethambutol
embA 4244708 c.1476C>G synonymous_variant 0.25 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.31 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.32 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.32 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.32 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.33 ethambutol
embA 4245222 c.1990_1992delTATinsCG frameshift_variant&missense_variant 0.37 ethambutol Uncertain significance
embA 4245248 c.2016G>C synonymous_variant 0.44 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.47 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.44 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.43 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.4 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.41 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.42 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.43 ethambutol
embA 4245315 p.Val695Thr missense_variant 0.38 ethambutol
embA 4245328 p.Ala699Val missense_variant 0.32 ethambutol
embA 4245335 c.2103A>G synonymous_variant 0.32 ethambutol
embA 4245340 p.Gly703Ala missense_variant 0.3 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.3 ethambutol
embA 4245348 p.Ala706Thr missense_variant 0.3 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.29 ethambutol
embA 4245470 c.2238T>C synonymous_variant 0.26 ethambutol
embA 4245483 p.Gln751Ala missense_variant 0.28 ethambutol
embA 4245490 p.Val753Ala missense_variant 0.3 ethambutol
embA 4245501 c.2269_2271delGCGinsAC frameshift_variant&missense_variant 0.29 ethambutol Uncertain significance
embA 4245509 c.2277A>G synonymous_variant 0.3 ethambutol
embA 4245512 c.2280G>C synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4245518 c.-996A>G upstream_gene_variant 0.3 ethambutol
embA 4245524 c.2292G>C synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embB 4245527 c.-987C>G upstream_gene_variant 0.3 ethambutol
embB 4245530 c.-984T>C upstream_gene_variant 0.29 ethambutol
embA 4245531 p.Ile767Val missense_variant 0.28 ethambutol
embA 4245535 p.Ser768Asn missense_variant 0.29 ethambutol
embB 4245539 c.-975C>G upstream_gene_variant 0.3 ethambutol
embB 4245542 c.-972C>G upstream_gene_variant 0.3 ethambutol
embB 4245557 c.-957G>A upstream_gene_variant 0.42 ethambutol
embB 4245575 c.-939C>G upstream_gene_variant 0.41 ethambutol
embA 4245576 c.2344_2346delAAGinsCA frameshift_variant&missense_variant 0.4 ethambutol Uncertain significance
embB 4245635 c.-879A>G upstream_gene_variant 0.29 ethambutol
embB 4245638 c.-876C>G upstream_gene_variant 0.29 ethambutol
embA 4245652 p.Thr807Ser missense_variant 0.32 ethambutol
embB 4245659 c.-855C>G upstream_gene_variant 0.37 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.46 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.41 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.33 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.32 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.38 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.39 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.55 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.57 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.6 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.6 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.63 ethambutol Uncertain significance
embB 4245812 c.-702G>C upstream_gene_variant 0.6 ethambutol
embA 4245813 c.2581_2583delCCCinsGG frameshift_variant&missense_variant 0.6 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 0.6 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.6 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.62 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.64 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.64 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.64 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.64 ethambutol
embA 4245885 p.Asp885Thr missense_variant 0.42 ethambutol
embA 4245892 p.Ile887Thr missense_variant 0.39 ethambutol Uncertain significance
embA 4245899 c.2667C>G synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4245902 c.-612G>A upstream_gene_variant 0.39 ethambutol
embB 4245905 c.-609C>G upstream_gene_variant 0.37 ethambutol
embB 4245911 c.-603A>G upstream_gene_variant 0.35 ethambutol
embB 4245917 c.-597G>A upstream_gene_variant 0.35 ethambutol
embA 4245930 p.Gly900Arg missense_variant 0.35 ethambutol
embA 4246041 p.Asp937Asn missense_variant 0.24 ethambutol
embA 4246055 c.2823T>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4246064 c.-450T>C upstream_gene_variant 0.45 ethambutol
embA 4246080 c.2848_2850delCCTinsTC frameshift_variant&missense_variant 0.45 ethambutol Uncertain significance
embA 4246088 c.2856A>G synonymous_variant 0.49 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.51 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.5 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.46 ethambutol
embA 4246128 c.2896_2898delTCTinsAC frameshift_variant&missense_variant 0.47 ethambutol Uncertain significance
embA 4246138 p.Arg969Gln missense_variant 0.47 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 0.47 ethambutol
embA 4246143 p.Ile971Val missense_variant 0.48 ethambutol
embA 4246151 c.2919A>G synonymous_variant 0.49 ethambutol Not assoc w R - Interim
embA 4246152 p.Ala974Gln missense_variant 0.49 ethambutol
embB 4246157 c.-357A>G upstream_gene_variant 0.49 ethambutol
embA 4246164 c.2932T>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embB 4246184 c.-330A>C upstream_gene_variant 0.62 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.61 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.62 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.61 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.6 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.59 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.58 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.6 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.6 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.64 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.67 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.66 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.68 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.74 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.73 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.73 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.73 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.73 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.72 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.69 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.67 ethambutol Uncertain significance
embB 4246367 c.-147C>T upstream_gene_variant 0.69 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.67 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.65 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embB 4246400 c.-114G>C upstream_gene_variant 0.63 ethambutol
embA 4246413 p.His1061Phe missense_variant 0.44 ethambutol
embA 4246419 c.3187C>T synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4246430 c.-84C>T upstream_gene_variant 0.21 ethambutol
embB 4247347 c.834G>C synonymous_variant 0.3 ethambutol
embB 4247348 p.Thr279Ala missense_variant 0.32 ethambutol
embB 4247355 p.Ala281Val missense_variant 0.42 ethambutol Uncertain significance
embB 4247358 p.Val282Ala missense_variant 0.45 ethambutol Uncertain significance
embB 4247365 c.852A>C synonymous_variant 0.54 ethambutol
embB 4247371 c.858C>G synonymous_variant 0.56 ethambutol
embB 4247375 p.Leu288Val missense_variant 0.57 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.61 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.64 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.66 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.7 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.7 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.72 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.75 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.75 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.75 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.77 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.78 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.81 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.82 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.78 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.78 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.75 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.71 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.71 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.69 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.69 ethambutol
embB 4247588 c.1075_1077delCTAinsAC frameshift_variant&missense_variant 0.69 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.7 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.66 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.59 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.57 ethambutol
embB 4247638 c.1125G>T synonymous_variant 0.53 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.51 ethambutol Not assoc w R
embB 4247656 c.1143A>G synonymous_variant 0.45 ethambutol
embB 4247659 c.1146C>G synonymous_variant 0.41 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.44 ethambutol
embB 4247683 c.1170C>G synonymous_variant 0.55 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.59 ethambutol
embB 4247716 c.1203C>T synonymous_variant 0.58 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.58 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.61 ethambutol
embB 4247729 p.Gly406Pro missense_variant 0.6 ethambutol
embB 4247746 c.1233C>T synonymous_variant 0.68 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.69 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.71 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.73 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.73 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.73 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.73 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.73 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.72 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.76 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.73 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.73 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.73 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.74 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.73 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.73 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.71 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.73 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.73 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.72 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.69 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.73 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.71 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.7 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.72 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.64 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.55 ethambutol Uncertain significance
embB 4248070 c.1557T>C synonymous_variant 0.74 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.75 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.76 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.74 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.72 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.72 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.8 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.78 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.77 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.77 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.76 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.78 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.75 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.69 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.68 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.6 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.6 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.58 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.55 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.56 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.56 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.52 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.46 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 0.4 ethambutol
embB 4248410 c.1897_1899delTTCinsCG frameshift_variant&missense_variant 0.39 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.37 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.35 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.34 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.32 ethambutol
embB 4248472 c.1959T>C synonymous_variant 0.3 ethambutol
embB 4248475 c.1962G>C synonymous_variant 0.28 ethambutol
embB 4248488 c.1975_1977delGCGinsAC frameshift_variant&missense_variant 0.3 ethambutol
embB 4248504 p.Asp664Gly missense_variant 0.3 ethambutol Uncertain significance
embB 4248508 c.1995G>A synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4248512 c.1999_2001delACAinsTG frameshift_variant&stop_gained 0.29 ethambutol
embB 4249268 p.Asp919Tyr missense_variant 0.28 ethambutol
embB 4249276 c.2763A>G synonymous_variant 0.31 ethambutol
embB 4249277 p.Tyr922Asn missense_variant 0.31 ethambutol
embB 4249282 c.2769A>C synonymous_variant 0.31 ethambutol
embB 4249291 c.2778C>A synonymous_variant 0.35 ethambutol
embB 4249297 c.2784G>C synonymous_variant 0.33 ethambutol
embB 4249312 c.2799C>T synonymous_variant 0.34 ethambutol
embB 4249321 c.2808A>C synonymous_variant 0.31 ethambutol
embB 4249322 c.2809_2811delGCAinsTC frameshift_variant&missense_variant 0.3 ethambutol
embB 4249325 c.2812_2814delAAGinsGC frameshift_variant&missense_variant 0.29 ethambutol
embB 4249333 c.2820C>G synonymous_variant 0.3 ethambutol
embB 4249336 c.2823C>G synonymous_variant 0.3 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.29 ethambutol
embB 4249342 c.2829C>G synonymous_variant 0.33 ethambutol
embB 4249348 c.2835G>C synonymous_variant 0.35 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.44 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.59 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.6 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.61 ethambutol
embB 4249384 c.2871G>T synonymous_variant 0.59 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.61 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.58 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.58 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.59 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.61 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.65 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.74 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.73 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.73 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.7 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.67 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.68 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.68 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.67 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.67 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.67 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 0.67 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.68 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.67 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.61 ethambutol
embB 4249606 c.3093C>A synonymous_variant 0.51 ethambutol
embB 4249609 c.3096T>C synonymous_variant 0.5 ethambutol
embB 4249615 c.3102C>G synonymous_variant 0.49 ethambutol
embB 4249618 c.3105C>G synonymous_variant 0.49 ethambutol
embB 4249624 c.3111C>G synonymous_variant 0.49 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.49 ethambutol
embB 4249640 c.3127T>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
aftB 4267214 c.1623A>C synonymous_variant 0.37 ethambutol
aftB 4267241 c.1596G>C synonymous_variant 0.52 ethambutol
aftB 4267244 c.1593T>C synonymous_variant 0.51 ethambutol
aftB 4267256 c.1581C>G synonymous_variant 0.51 ethambutol
aftB 4267262 c.1575T>C synonymous_variant 0.48 ethambutol
aftB 4267266 p.Ala524Gly missense_variant 0.48 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 0.48 ethambutol
aftB 4267274 c.1563G>C synonymous_variant 0.48 ethambutol
aftB 4267289 p.Ala516Gln missense_variant 0.49 ethambutol
aftB 4267292 c.1545C>G synonymous_variant 0.5 ethambutol
aftB 4267297 c.1540T>C synonymous_variant 0.49 ethambutol
aftB 4267301 c.1536C>T synonymous_variant 0.49 ethambutol
aftB 4267304 p.Val511Ala missense_variant 0.49 ethambutol
aftB 4267316 c.1521A>G synonymous_variant 0.51 ethambutol
aftB 4267325 c.1512G>C synonymous_variant 0.52 ethambutol
aftB 4267334 c.1503T>C synonymous_variant 0.52 ethambutol Not assoc w R - Interim
aftB 4267355 c.1480_1482delCTAinsGC frameshift_variant&missense_variant 0.4 ethambutol Uncertain significance
aftB 4267364 c.1471_1473delATGinsCC frameshift_variant&missense_variant 0.33 ethambutol Uncertain significance
aftB 4268066 c.769_771delGTGinsCC frameshift_variant&missense_variant 0.33 ethambutol Uncertain significance
aftB 4268081 c.756A>G synonymous_variant 0.59 ethambutol
aftB 4268084 c.753G>C synonymous_variant 0.61 ethambutol
aftB 4268096 c.741C>G synonymous_variant 0.68 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.68 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.7 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.74 ethambutol
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 0.74 ethambutol Uncertain significance
aftB 4268129 c.708T>G synonymous_variant 0.72 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.71 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.66 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.65 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.65 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.65 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.63 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.63 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.63 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.6 ethambutol
aftB 4268213 c.624T>G synonymous_variant 0.59 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.48 ethambutol
aftB 4268236 p.Leu201Met missense_variant 0.38 ethambutol
ubiA 4268928 c.906C>T synonymous_variant 0.32 ethambutol Not assoc w R
aftB 4268940 c.-104T>C upstream_gene_variant 0.32 ethambutol
aftB 4268946 c.-110G>A upstream_gene_variant 0.32 ethambutol
ubiA 4268951 p.Val295Ile missense_variant 0.32 ethambutol
aftB 4268952 c.-116G>C upstream_gene_variant 0.32 ethambutol
aftB 4268955 c.-119A>G upstream_gene_variant 0.34 ethambutol
aftB 4268958 c.-122A>C upstream_gene_variant 0.35 ethambutol
ubiA 4268969 p.Leu289Val missense_variant 0.34 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 0.38 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.38 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.37 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.37 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.34 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.32 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.32 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.32 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.31 ethambutol
aftB 4269075 c.-239T>C upstream_gene_variant 0.25 ethambutol
aftB 4269159 c.-323G>C upstream_gene_variant 0.25 ethambutol
ubiA 4269164 p.Leu224Met missense_variant 0.25 ethambutol
aftB 4269165 c.-329G>C upstream_gene_variant 0.25 ethambutol
aftB 4269179 c.-343C>A upstream_gene_variant 0.25 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.25 ethambutol
aftB 4269186 c.-350C>G upstream_gene_variant 0.25 ethambutol
ubiA 4269329 p.Lys169Glu missense_variant 0.33 ethambutol
aftB 4269342 c.-506G>C upstream_gene_variant 0.36 ethambutol
ubiA 4269357 c.475_477delATCinsCG frameshift_variant&missense_variant 0.36 ethambutol
aftB 4269362 c.-526T>C upstream_gene_variant 0.34 ethambutol
aftB 4269363 c.-527T>C upstream_gene_variant 0.34 ethambutol
aftB 4269372 c.-536G>A upstream_gene_variant 0.36 ethambutol
ubiA 4269380 p.Val152Ile missense_variant 0.32 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 0.32 ethambutol Not assoc w R
ubiA 4269390 c.442_444delGTGinsCT frameshift_variant&missense_variant 0.28 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R