TB-Profiler result

Run: ERR6866547
Summary

Run ID: ERR6866547

Sample name:

Date: 2024-04-16T02:46:31.996831

Number of reads: 220782

Percentage reads mapped: 11.67

Median coverage: 1.0

Strain: La1.7;lineage4.9;lineage6

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.7 M.bovis None 0.18
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.94
lineage6 West-Africa 2 RD702 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 645 c.645A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 1.0 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1189 c.1189_1191delATTinsGC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1195 c.1195_1197delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1206 c.1206G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 1.0 isoniazid
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7415 c.114C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7418 c.117C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7460 c.159C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7568 c.267C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7607 c.306C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7613 c.312G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7625 c.324G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7778 c.477G>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7793 c.492G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7796 c.495G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7823 c.522G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7829 c.528C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7853 c.552C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8401 p.Asp367Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8429 c.1128C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8628 c.1327C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8649 p.Arg450Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8777 c.1476C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8843 c.1542G>A synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8952 p.Gln551Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8957 c.1656C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Asn missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9059 c.1758G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9213 p.Thr638Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9324 c.2023_2025delTCGinsAGT synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9368 c.2067G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9401 c.2100G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491500 p.Glu240Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491532 c.750G>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575740 c.393G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620427 c.537C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620605 c.715_717delGTTinsAC frameshift_variant&missense_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620764 c.874_876delGCCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620790 c.900C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620809 c.919C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620818 c.928_930delGTTinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>T synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734448 c.195C>T synonymous_variant 0.93 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.93 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.93 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.93 rifampicin
nusG 734470 c.217_219delCTTinsTG frameshift_variant&missense_variant 0.93 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734526 c.273G>A synonymous_variant 0.94 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760082 c.276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760346 c.540C>T synonymous_variant 1.0 rifampicin
rpoB 760356 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.94 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.91 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.92 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.92 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.92 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.93 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.94 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.94 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.94 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.94 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.91 rifampicin
rpoB 760679 c.873A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.89 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 0.91 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.95 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.95 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.95 rifampicin
rpoB 760784 c.978G>C synonymous_variant 0.94 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.93 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.91 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.8 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.8 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.87 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.87 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761186 c.1380G>A synonymous_variant 0.91 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsGC frameshift_variant&missense_variant 0.8 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.8 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.95 rifampicin
rpoB 761339 c.1533C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.93 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.93 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.93 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.93 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.93 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.93 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.96 rifampicin
rpoB 761604 c.1798_1800delCTCinsTG frameshift_variant&missense_variant 0.96 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 1.0 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 1.0 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 1.0 rifampicin
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 0.64 rifampicin
rpoB 761727 p.Ser641Ala missense_variant 1.0 rifampicin
rpoB 761736 p.Ile644Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761807 c.2001C>T synonymous_variant 0.93 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.93 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.93 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.92 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.92 rifampicin
rpoB 761861 c.2055C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761864 c.2058G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.91 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 0.91 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.91 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.93 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.93 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.93 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.91 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.91 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.93 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>T synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.96 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.96 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.96 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.95 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.95 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.94 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.94 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.92 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.91 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.9 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.92 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.95 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.96 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.94 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.94 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.94 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.93 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 1.0 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>G upstream_gene_variant 0.96 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.94 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.94 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.94 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.95 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.95 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.94 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.94 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.92 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.92 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.92 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.92 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.92 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.91 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.9 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.9 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 1.0 rifampicin
rpoC 763484 c.115_117delCTTinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.97 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.97 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 0.97 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.97 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.97 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.91 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.97 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.95 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.95 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.95 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.96 rifampicin
rpoC 763867 c.498C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763871 p.Gly168Ser missense_variant 0.95 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.96 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.96 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.95 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.95 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.96 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.96 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.95 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.95 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.95 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764207 p.Val280Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764227 c.858G>C synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764263 c.894G>T synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.97 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.97 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.97 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.97 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.97 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.97 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 0.98 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.98 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.98 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.97 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 0.97 rifampicin
rpoC 764854 c.1485G>C synonymous_variant 0.97 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>A synonymous_variant 0.93 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 0.95 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.95 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.95 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.96 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.95 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766034 p.His889Asn missense_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766624 c.3255G>C synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766658 c.3289_3291delCGGinsGT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 1.0 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>A synonymous_variant 1.0 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775736 c.2745C>G synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775754 c.2727C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775763 c.2718T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775769 p.Ala904Gly missense_variant 0.75 clofazimine
bedaquiline
mmpL5 775772 p.Met903Ile missense_variant 0.75 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775780 p.Thr901Ala missense_variant 0.76 clofazimine
bedaquiline
mmpL5 775784 c.2697G>A synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775793 c.2688C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775796 c.2683_2685delTTTinsAG frameshift_variant&stop_gained 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775814 c.2667C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 775832 c.2647_2649delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775838 c.2643G>C synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 775847 c.2634G>A synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775851 p.Ser877Thr missense_variant 0.76 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Leu missense_variant 0.82 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775901 c.2580G>A synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775910 c.2571G>A synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775916 c.2565T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775922 c.2559G>A synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775955 c.2524_2526delATCinsGG frameshift_variant&missense_variant 0.54 clofazimine Uncertain significance
bedaquiline Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 0.91 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.91 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.92 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.91 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.92 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.95 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.95 streptomycin
rpsL 781718 c.159C>T synonymous_variant 0.95 streptomycin
rpsL 781724 c.165G>A synonymous_variant 0.94 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.94 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800543 c.-266C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.94 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.94 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.94 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.94 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.94 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.95 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.95 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.96 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 0.95 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.95 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.96 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.96 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.96 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.91 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.92 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.9 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.9 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.9 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.9 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.9 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.94 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.94 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.93 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.92 linezolid
rplC 800877 c.69A>C synonymous_variant 0.9 linezolid
rplC 800880 c.72A>C synonymous_variant 0.91 linezolid
rplC 800889 c.81C>G synonymous_variant 0.92 linezolid
rplC 800892 c.84G>C synonymous_variant 0.92 linezolid
rplC 800895 c.87C>G synonymous_variant 0.93 linezolid
rplC 800904 c.96G>C synonymous_variant 0.95 linezolid
rplC 800916 c.108A>G synonymous_variant 0.95 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.95 linezolid
rplC 800928 c.120C>T synonymous_variant 0.95 linezolid
rplC 800931 c.123G>C synonymous_variant 0.95 linezolid
rplC 800937 c.129A>G synonymous_variant 0.95 linezolid
rplC 800940 c.132C>T synonymous_variant 0.95 linezolid
rplC 800946 c.138T>C synonymous_variant 0.95 linezolid
rplC 800949 c.141T>C synonymous_variant 0.95 linezolid
rplC 800964 c.156G>C synonymous_variant 0.95 linezolid
rplC 800985 c.177A>G synonymous_variant 0.94 linezolid
rplC 801004 c.196_198delCTGinsGC frameshift_variant&missense_variant 0.92 linezolid
rplC 801009 c.201A>C synonymous_variant 0.92 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.92 linezolid
rplC 801027 c.219C>G synonymous_variant 0.9 linezolid
fbiC 1304511 c.1581C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304577 c.1647C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304727 c.1797A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
sigE 1364667 c.255T>C synonymous_variant 0.7 pyrazinamide
sigE 1364682 c.270G>A synonymous_variant 0.8 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.8 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.82 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 0.85 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.88 pyrazinamide
sigE 1364718 c.306C>A synonymous_variant 0.88 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.88 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.88 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.88 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 1.0 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 1.0 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_647delTCCTTTTCCTCTCCGGAGinsCTCGCTTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474420 n.764_769delGCGCAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474428 n.771C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.41 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674514 p.Ile105Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674534 c.333G>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.97 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.96 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674573 c.372G>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.93 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674606 c.405G>T synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674610 p.Ile137Val missense_variant 0.95 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 0.95 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 0.95 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.94 ethionamide
isoniazid
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.95 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.95 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.95 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833859 c.318C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.97 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.94 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.97 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.93 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.92 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.92 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834318 c.777C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.94 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.96 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.97 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.95 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834645 c.1104C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.95 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.94 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.94 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.88 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.86 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.86 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.94 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.94 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.94 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.94 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.94 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.94 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.94 linezolid
tsnR 1853417 c.-189G>T upstream_gene_variant 0.95 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.95 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.95 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.95 linezolid
tsnR 1853441 c.-165C>T upstream_gene_variant 0.93 linezolid
tsnR 1853453 c.-153G>T upstream_gene_variant 0.92 linezolid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155696 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.6 isoniazid
katG 2155737 c.375C>T synonymous_variant 1.0 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.56 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.53 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>A synonymous_variant 0.53 isoniazid Not assoc w R - Interim
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2519128 c.1014G>A synonymous_variant 1.0 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 1.0 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 1.0 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 1.0 isoniazid
thyX 3067391 c.555G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067733 c.213G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067771 p.Gly59Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067784 c.162C>G synonymous_variant 1.0 para-aminosalicylic_acid
mtrB 3625267 c.1347T>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625282 c.-372C>G upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.93 bedaquiline
rifampicin
lpqB 3625312 c.-402G>T upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625318 c.-408G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625325 p.His430Arg missense_variant 0.92 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626792 c.-179G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626864 c.484_486delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626894 c.-281C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 1.0 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 1.0 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.96 rifampicin
rpoA 3877803 c.705G>A synonymous_variant 0.97 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.97 rifampicin
rpoA 3877865 c.643C>T synonymous_variant 0.97 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.97 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.97 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 1.0 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 1.0 rifampicin
rpoA 3878001 c.505_507delTCAinsAGC synonymous_variant 1.0 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.93 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.93 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.93 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 0.93 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.93 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.93 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.94 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 0.95 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.93 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.94 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 0.94 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.94 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.95 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.95 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.95 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 1.0 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878244 c.264G>A synonymous_variant 1.0 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878989 c.-482G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
clpC1 4038383 c.2322G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038407 c.2298G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038434 c.2271G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 1.0 pyrazinamide
clpC1 4038461 c.2244G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038474 p.Ser744Thr missense_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 1.0 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.96 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.96 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.96 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.97 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.96 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 1.0 pyrazinamide
clpC1 4038683 c.2020_2022delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038821 c.1884G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038896 c.1809C>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>T synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039109 c.1596C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039336 c.1369C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>A synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039840 c.865C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039844 c.861C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040003 c.702G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040030 c.675C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040108 c.597G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040141 c.564C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040177 c.528C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040201 c.504C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.93 pyrazinamide
clpC1 4040213 p.Ser164Asn missense_variant 0.93 pyrazinamide
clpC1 4040219 c.486C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.93 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.93 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.91 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040360 c.345G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040372 c.333C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.96 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040495 c.210C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.96 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.96 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.96 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
glpK 4138529 c.1227G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138550 c.1206C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138565 c.1191G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138661 c.1095T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138685 c.1071C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138696 p.Pro354Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138697 c.1059C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138727 c.1029C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138775 c.981C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138787 c.969C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138796 c.960A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138805 c.951C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240747 c.885C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240756 c.894G>C synonymous_variant 1.0 ethambutol
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240786 c.924C>T synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240822 c.960C>A synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>C synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240858 c.996G>C synonymous_variant 1.0 ethambutol
embC 4240867 c.1005T>C synonymous_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240874 c.1012_1013delAGinsTC synonymous_variant 1.0 ethambutol
embC 4240879 c.1017G>C synonymous_variant 1.0 ethambutol
embC 4240880 p.Ala340Ser missense_variant 1.0 ethambutol
embC 4240885 c.1023T>C synonymous_variant 1.0 ethambutol
embC 4240892 p.Met344Leu missense_variant 1.0 ethambutol
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4240900 c.1038A>T synonymous_variant 1.0 ethambutol
embC 4240911 p.Ala350Val missense_variant 1.0 ethambutol
embC 4240936 c.1074A>G synonymous_variant 1.0 ethambutol
embC 4240981 c.1119G>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embC 4240983 p.Ser374Asn missense_variant 0.9 ethambutol
embC 4240990 c.1128A>G synonymous_variant 0.9 ethambutol
embC 4240993 c.1131G>C synonymous_variant 0.9 ethambutol
embC 4240996 c.1134G>C synonymous_variant 0.9 ethambutol
embC 4241002 c.1140G>C synonymous_variant 0.9 ethambutol
embC 4241008 c.1146G>C synonymous_variant 0.9 ethambutol
embC 4241011 c.1149C>A synonymous_variant 0.9 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.9 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.9 ethambutol
embC 4241024 p.Val388Phe missense_variant 0.9 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.91 ethambutol
embC 4241047 c.1185C>A synonymous_variant 0.92 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.92 ethambutol
embC 4241053 c.1191G>T synonymous_variant 0.92 ethambutol
embC 4241074 c.1212G>C synonymous_variant 1.0 ethambutol
embC 4241545 c.1683T>C synonymous_variant 0.91 ethambutol
embC 4241548 c.1686T>G synonymous_variant 0.92 ethambutol
embC 4241560 c.1698C>G synonymous_variant 1.0 ethambutol
embC 4241567 p.Ile569Val missense_variant 1.0 ethambutol
embC 4241584 c.1722T>C synonymous_variant 1.0 ethambutol
embC 4241587 c.1725C>G synonymous_variant 1.0 ethambutol
embC 4241593 c.1731C>G synonymous_variant 1.0 ethambutol
embC 4241614 c.1752A>C synonymous_variant 1.0 ethambutol
embC 4241626 c.1764T>C synonymous_variant 1.0 ethambutol
embC 4241635 c.1773G>T synonymous_variant 1.0 ethambutol
embC 4241644 c.1782G>C synonymous_variant 1.0 ethambutol
embC 4241648 c.1786T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>A synonymous_variant 1.0 ethambutol
embC 4241665 c.1803G>C synonymous_variant 1.0 ethambutol
embC 4241671 c.1809T>G synonymous_variant 1.0 ethambutol
embC 4241674 c.1812C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241683 c.1821G>T synonymous_variant 1.0 ethambutol
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.92 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.93 ethambutol
embB 4248106 c.1593C>G synonymous_variant 0.93 ethambutol
embB 4248112 c.1599C>G synonymous_variant 0.94 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.92 ethambutol
embB 4248127 c.1614G>A synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4248133 c.1620C>G synonymous_variant 0.91 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.91 ethambutol
embB 4248143 c.1630_1632delTTGinsAC frameshift_variant&missense_variant 0.91 ethambutol
embB 4248146 p.Ile545Val missense_variant 0.91 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.91 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.91 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.91 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.92 ethambutol
embB 4248196 c.1683G>A synonymous_variant 0.94 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.94 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.94 ethambutol
embB 4248217 c.1704C>G synonymous_variant 0.89 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.88 ethambutol Uncertain significance
embB 4248233 c.1720C>T synonymous_variant 0.94 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.93 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.92 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.92 ethambutol
embB 4248259 p.Met582Ile missense_variant 0.91 ethambutol
embB 4248269 p.Met586Gln missense_variant 0.91 ethambutol
embB 4248275 c.1762_1764delACGinsGC frameshift_variant&missense_variant 0.91 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.83 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.8 ethambutol