Run ID: ERR4818021
Sample name:
Date: 2024-10-03T20:06:37.626852
Number of reads: 884841
Percentage reads mapped: 49.99
Median coverage: 28.0
Strain: La1.2.BCG;La1.8.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.8 | M.bovis | None | 0.89 |
La1.8.1 | M.bovis | None | 0.94 |
La1.2.BCG | M.bovis | None | 0.09 |
La1 | M.bovis | None | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Leu359Ile | Uncertain significance | Mutation from literature | ||
p.Tyr384Asn | Mutation from literature | |||
p.Ala388Gly | Mutation from literature | |||
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | pncA | p.His57Asp | Assoc w R | |
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
pncA | 2289073 | p.His57Asp | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
embB | 4247448 | p.His312Arg | missense_variant | 0.7 | ethambutol | Mutation from literature | |
embB | 4247588 | p.Leu359Ile | missense_variant | 0.52 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4247663 | p.Tyr384Asn | missense_variant | 0.36 | ethambutol | Mutation from literature | |
embB | 4247676 | p.Ala388Gly | missense_variant | 0.41 | ethambutol | Mutation from literature | |
embB | 4247708 | p.Asn399Asp | missense_variant | 0.47 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 467 | p.His156Arg | missense_variant | 1.0 | isoniazid | Not assoc w R |
dnaA | 558 | c.558G>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 561 | p.His187Gln | missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 567 | c.567C>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 588 | c.588A>C | synonymous_variant | 0.26 | isoniazid | |
dnaA | 591 | c.591C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 597 | c.597C>G | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
dnaA | 600 | c.600T>A | synonymous_variant | 0.31 | isoniazid | |
dnaA | 612 | c.612G>C | synonymous_variant | 0.42 | isoniazid | |
dnaA | 627 | c.627G>A | synonymous_variant | 0.43 | isoniazid | |
dnaA | 645 | c.645A>C | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 649 | c.649C>T | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 0.41 | isoniazid | |
dnaA | 660 | c.660G>C | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 669 | c.669C>T | synonymous_variant | 0.36 | isoniazid | |
dnaA | 672 | c.672T>C | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 0.35 | isoniazid | Not assoc w R - Interim |
dnaA | 681 | c.681G>C | synonymous_variant | 0.34 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.36 | isoniazid | |
dnaA | 720 | c.720G>A | synonymous_variant | 0.36 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.36 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.28 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.3 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805_807delTTGinsCTC | synonymous_variant | 0.35 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.36 | isoniazid | |
dnaA | 819 | c.819C>T | synonymous_variant | 0.37 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.38 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.39 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 876 | c.876C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 882 | c.882C>T | synonymous_variant | 0.37 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.46 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.41 | isoniazid | Not assoc w R - Interim |
dnaA | 942 | c.942C>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.34 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.32 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 969 | c.969G>A | synonymous_variant | 0.29 | isoniazid | |
dnaA | 975 | c.975G>T | synonymous_variant | 0.28 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 996 | c.996A>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 999 | c.999C>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1003 | c.1003C>T | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1041 | c.1041G>A | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1137 | c.1137C>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1143 | c.1143G>C | synonymous_variant | 0.43 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1188 | c.1188G>A | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1197 | c.1197T>C | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1218 | c.1218C>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.36 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.45 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.45 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.49 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 1311 | c.1311C>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1320 | c.1320G>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1323 | c.1323C>T | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.34 | isoniazid | Not assoc w R - Interim |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1375 | c.1375T>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.23 | isoniazid | |
gyrB | 5752 | c.513G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6304 | c.-998C>G | upstream_gene_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6406 | c.1167C>T | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6446 | p.Ala403Ser | missense_variant | 0.9 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6865 | c.-437G>A | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | p.Ser629Thr | missense_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7406 | c.105G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7562 | c.261C>T | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382_384delAGGinsCGC | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>A | synonymous_variant | 0.49 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7721 | c.420G>A | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7725 | c.424C>T | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7796 | c.495G>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7814 | c.513C>G | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7823 | c.522G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8048 | c.747C>A | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>A | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>A | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8237 | c.936A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8276 | c.975G>A | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.45 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8337 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>T | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8367 | c.1066C>T | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | p.Tyr364His | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8400 | p.Asp367Asn | missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8417 | c.1116C>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>A | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.51 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8708 | c.1407G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8750 | c.1449C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Ser | missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.55 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8807 | c.1506C>T | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8816 | c.1515C>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.58 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.24 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9217 | p.Asp639Ala | missense_variant | 0.6 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9293 | c.1992G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | c.2007C>T | synonymous_variant | 0.46 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9312 | c.2011C>T | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9317 | c.2016G>T | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9365 | c.2064G>A | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13197 | p.Thr121Ser | missense_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13228 | c.330delG | frameshift_variant | 1.0 | isoniazid | Uncertain significance |
Rv0010c | 13460 | c.99T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490935 | c.153C>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490962 | c.180T>G | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490977 | c.195C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490984 | p.Leu68Ile | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490987 | p.Leu69Thr | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491001 | c.219G>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491082 | c.300T>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491083 | p.Val101Ile | missense_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491100 | c.318C>T | synonymous_variant | 0.4 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491173 | c.391C>A | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.51 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491643 | c.861G>A | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491649 | c.867C>T | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491661 | c.879C>G | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491687 | p.Thr302Lys | missense_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491697 | c.915G>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 574712 | c.-636A>G | upstream_gene_variant | 0.38 | isoniazid | |
ethionamide | ||||||
mshA | 574718 | c.-630A>G | upstream_gene_variant | 0.36 | isoniazid | |
ethionamide | ||||||
mshA | 574724 | c.-624T>C | upstream_gene_variant | 0.39 | isoniazid | |
ethionamide | ||||||
mshA | 574731 | c.-617A>G | upstream_gene_variant | 0.39 | isoniazid | |
ethionamide | ||||||
mshA | 574739 | c.-609T>C | upstream_gene_variant | 0.41 | isoniazid | |
ethionamide | ||||||
mshA | 575665 | c.318G>A | synonymous_variant | 0.33 | isoniazid | |
ethionamide | ||||||
mshA | 575674 | c.327G>C | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.41 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575701 | c.354G>A | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
mshA | 575704 | c.357T>G | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.39 | isoniazid | |
ethionamide | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.47 | isoniazid | |
ethionamide | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.47 | isoniazid | |
ethionamide | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.44 | isoniazid | |
ethionamide | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
mshA | 575755 | c.408G>A | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575756 | c.409C>T | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.49 | isoniazid | |
ethionamide | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
mshA | 575809 | c.462C>T | synonymous_variant | 0.55 | isoniazid | |
ethionamide | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.54 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.59 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.59 | isoniazid | |
ethionamide | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
mshA | 575833 | c.486C>G | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 0.61 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.49 | isoniazid | |
ethionamide | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.49 | isoniazid | |
ethionamide | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.47 | isoniazid | |
ethionamide | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.49 | isoniazid | |
ethionamide | ||||||
mshA | 575920 | c.573C>G | synonymous_variant | 0.49 | isoniazid | |
ethionamide | ||||||
mshA | 575924 | p.Gly193Ser | missense_variant | 0.45 | isoniazid | |
ethionamide | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
mshA | 575965 | c.618C>G | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.6 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619528 | c.-363C>G | upstream_gene_variant | 0.54 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619531 | c.-360T>C | upstream_gene_variant | 0.54 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 0.52 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.52 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.53 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.49 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619609 | c.-282G>T | upstream_gene_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.32 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620226 | c.336G>A | synonymous_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620245 | c.355T>C | synonymous_variant | 0.45 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620254 | c.364_366delCTCinsTTG | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620268 | c.378G>C | synonymous_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.45 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.43 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.43 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.4 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.43 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.37 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>A | synonymous_variant | 0.34 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.34 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620460 | c.570T>G | synonymous_variant | 0.3 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620461 | p.Val191Ile | missense_variant | 0.3 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620631 | c.741T>G | synonymous_variant | 0.31 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.32 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620659 | c.769_771delCGCinsAGG | synonymous_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620664 | c.774C>T | synonymous_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.4 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620688 | c.798G>C | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620710 | p.Val274Ile | missense_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.34 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.37 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.38 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.38 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620742 | c.852G>C | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620763 | c.873G>A | synonymous_variant | 0.45 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620769 | c.879C>G | synonymous_variant | 0.45 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.32 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 0.23 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.26 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.24 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.26 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.31 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.35 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.42 | ethionamide | |
hadA | 731682 | c.-248C>G | upstream_gene_variant | 0.28 | isoniazid | |
hadA | 731687 | c.-243_-242insCACAGATCTTTT | upstream_gene_variant | 0.29 | isoniazid | |
hadA | 731693 | c.-237C>A | upstream_gene_variant | 0.29 | isoniazid | |
hadA | 731696 | c.-233_-232delTT | upstream_gene_variant | 0.29 | isoniazid | |
hadA | 731708 | c.-222G>C | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731710 | c.-220A>T | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731711 | c.-219T>C | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731717 | c.-213T>G | upstream_gene_variant | 0.43 | isoniazid | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.53 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.54 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.64 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.52 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.56 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.46 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.4 | isoniazid | |
hadA | 731840 | c.-90G>C | upstream_gene_variant | 0.35 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.35 | isoniazid | |
hadA | 731849 | c.-81C>T | upstream_gene_variant | 0.32 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.32 | isoniazid | |
hadA | 731864 | c.-66C>T | upstream_gene_variant | 0.29 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.41 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.37 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.36 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.38 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.38 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.36 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.31 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.33 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.33 | isoniazid | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.29 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.29 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.29 | rifampicin | Uncertain significance |
nusG | 734123 | c.-131C>G | upstream_gene_variant | 0.26 | rifampicin | |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.25 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.25 | rifampicin | |
nusG | 734135 | c.-119G>C | upstream_gene_variant | 0.27 | rifampicin | |
nusG | 734144 | c.-110G>C | upstream_gene_variant | 0.27 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.26 | rifampicin | |
nusG | 734173 | c.-81C>G | upstream_gene_variant | 0.37 | rifampicin | |
nusG | 734175 | c.-79_-77delGGTinsCTG | upstream_gene_variant | 0.35 | rifampicin | |
nusG | 734180 | c.-74T>G | upstream_gene_variant | 0.35 | rifampicin | Uncertain significance |
nusG | 734183 | c.-71C>T | upstream_gene_variant | 0.35 | rifampicin | |
nusG | 734186 | c.-68G>C | upstream_gene_variant | 0.35 | rifampicin | Uncertain significance |
nusG | 734205 | c.-49A>C | upstream_gene_variant | 0.32 | rifampicin | |
nusG | 734329 | p.Ala26Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734407 | p.Val52Ile | missense_variant | 0.32 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.44 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.41 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.47 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.48 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.48 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.53 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.44 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.47 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.35 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.43 | rifampicin | |
nusG | 734601 | c.348C>G | synonymous_variant | 0.48 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.39 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.28 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.28 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760067 | c.261G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.51 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.5 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.59 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.6 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.44 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.38 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.49 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.58 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.35 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.49 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.51 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.46 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761439 | p.Asp545Lys | missense_variant | 0.35 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.38 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.37 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761720 | c.1914_1916delCGAinsGG | frameshift_variant&synonymous_variant | 0.58 | rifampicin | |
rpoB | 761727 | p.Ser641Gly | missense_variant | 0.6 | rifampicin | |
rpoB | 761728 | c.1923dupC | frameshift_variant | 0.6 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.56 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.53 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.54 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.54 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.51 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.5 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.47 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.55 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.58 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.61 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.61 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.6 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.64 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.64 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.55 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.5 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.5 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.38 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.33 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.47 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.5 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.48 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.41 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.38 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.33 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 762926 | c.3120C>T | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.59 | rifampicin | |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.59 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.51 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.51 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.45 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.65 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.62 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.72 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.67 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.66 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.66 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763942 | c.573C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763948 | c.579G>A | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763949 | c.580C>A | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763954 | c.585C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763963 | c.594C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.38 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.43 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.53 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.59 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765329 | p.Ser654Gly | missense_variant | 0.33 | rifampicin | |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.47 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.47 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.52 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.54 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.55 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.49 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.48 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.49 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.61 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.51 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766174 | p.Asn935Lys | missense_variant | 0.33 | rifampicin | |
rpoC | 766178 | p.Ile937Val | missense_variant | 0.28 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.25 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.37 | rifampicin | |
rpoC | 766549 | c.3180G>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.38 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.53 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766660 | c.3291G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.59 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 766882 | c.3513C>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.66 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.48 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.44 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.41 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.57 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.58 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767265 | p.Ala1299Glu | missense_variant | 0.21 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.25 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.28 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775991 | c.2490G>A | synonymous_variant | 0.2 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776002 | p.Leu827Met | missense_variant | 0.21 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776005 | p.Ile826Leu | missense_variant | 0.22 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.33 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776030 | c.2451G>A | synonymous_variant | 0.34 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776053 | c.2428T>C | synonymous_variant | 0.24 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776056 | p.Val809Leu | missense_variant | 0.24 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 777133 | p.Val450Ile | missense_variant | 0.27 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 0.33 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.32 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.35 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.35 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.36 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777194 | c.1287A>G | synonymous_variant | 0.36 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777206 | c.1275A>G | synonymous_variant | 0.33 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777212 | p.Ala423Thr | missense_variant | 0.32 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777215 | c.1266C>G | synonymous_variant | 0.33 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777218 | c.1263G>A | synonymous_variant | 0.33 | bedaquiline | |
clofazimine | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.46 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.5 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.51 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.57 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.59 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.62 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.64 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.7 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.71 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.65 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.66 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.61 | streptomycin | Uncertain significance |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.32 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.4 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.39 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.37 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.32 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.29 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.41 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.42 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.43 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.35 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.34 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.4 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.4 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.4 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.41 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.47 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.47 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.46 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.42 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.45 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.36 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.36 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.37 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.38 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.36 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.44 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.41 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.48 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.48 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.52 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.51 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.51 | linezolid | |
rplC | 801454 | p.Glu216Gln | missense_variant | 0.53 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
Rv1129c | 1254582 | c.-48A>G | upstream_gene_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 1.0 | pretomanid | |
delamanid | Uncertain significance | |||||
clofazimine | Uncertain significance | |||||
fbiC | 1303489 | c.559C>T | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303497 | c.567G>A | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303501 | c.571C>T | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303671 | c.741C>T | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303681 | c.751T>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.45 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.51 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.51 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303998 | c.1068T>G | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304049 | c.1119T>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304085 | c.1155C>T | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304106 | c.1176G>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304142 | c.1212G>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304161 | p.Arg411Ser | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304174 | p.Val415Ala | missense_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304184 | c.1254G>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304187 | c.1257T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304208 | c.1278C>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304499 | c.1569T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304511 | c.1581C>G | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304535 | c.1605G>A | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304545 | p.Val539Thr | missense_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304553 | c.1623C>T | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304671 | p.Val581Thr | missense_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304739 | c.1809C>T | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.51 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.51 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.66 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.84 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304862 | c.1932G>A | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.57 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305252 | c.2322G>A | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305276 | c.2346G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305279 | p.His783Gln | missense_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305282 | c.2352T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305297 | c.2367G>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305300 | c.2370A>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305303 | c.2373T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305306 | c.2376A>T | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305309 | c.2379G>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305310 | p.Arg794Glu | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305318 | c.2388C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305331 | p.Glu801Asn | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305336 | c.2406T>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305372 | c.2442G>A | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305384 | c.2454G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
embR | 1417554 | c.-207C>G | upstream_gene_variant | 1.0 | ethambutol | |
atpE | 1461132 | p.Val30Ile | missense_variant | 0.36 | bedaquiline | |
atpE | 1461149 | c.105T>G | synonymous_variant | 0.33 | bedaquiline | |
atpE | 1461150 | p.Ile36Val | missense_variant | 0.33 | bedaquiline | |
atpE | 1461158 | c.114T>G | synonymous_variant | 0.31 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 0.3 | bedaquiline | Uncertain significance |
atpE | 1461170 | c.126A>G | synonymous_variant | 0.26 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.25 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.26 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.26 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471935 | n.90T>C | non_coding_transcript_exon_variant | 0.77 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.32 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.42 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.55 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.64 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
inhA | 1673633 | c.-569G>A | upstream_gene_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1673637 | c.-565C>G | upstream_gene_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1673641 | c.-561G>A | upstream_gene_variant | 0.39 | isoniazid | |
ethionamide | ||||||
inhA | 1673715 | c.-487C>G | upstream_gene_variant | 0.65 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1673749 | c.-453_-452delAAinsCG | upstream_gene_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1673758 | c.-444A>G | upstream_gene_variant | 0.47 | isoniazid | |
ethionamide | ||||||
inhA | 1673941 | c.-261G>T | upstream_gene_variant | 0.48 | isoniazid | |
ethionamide | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.55 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.57 | isoniazid | |
ethionamide | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1674006 | c.-196T>G | upstream_gene_variant | 0.57 | isoniazid | |
ethionamide | ||||||
inhA | 1674015 | c.-187C>T | upstream_gene_variant | 0.5 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1674018 | c.-184G>C | upstream_gene_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674021 | c.-181G>C | upstream_gene_variant | 0.48 | isoniazid | |
ethionamide | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.45 | isoniazid | |
ethionamide | ||||||
inhA | 1674033 | c.-169T>C | upstream_gene_variant | 0.45 | isoniazid | |
ethionamide | ||||||
inhA | 1674037 | c.-165_-164delCAinsGC | upstream_gene_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1674042 | c.-160G>T | upstream_gene_variant | 0.47 | isoniazid | |
ethionamide | ||||||
inhA | 1674049 | c.-153_-151delCAAinsGAC | upstream_gene_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674054 | c.-148T>C | upstream_gene_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674060 | c.-142A>G | upstream_gene_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1674063 | c.-139G>C | upstream_gene_variant | 0.53 | isoniazid | |
ethionamide | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1674504 | c.303C>G | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.44 | isoniazid | |
ethionamide | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.39 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 0.43 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.44 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.55 | isoniazid | |
ethionamide | ||||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.44 | isoniazid | |
ethionamide | ||||||
inhA | 1674741 | c.540C>T | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674750 | c.549T>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674753 | c.552G>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>G | synonymous_variant | 0.35 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.36 | isoniazid | |
ethionamide | ||||||
inhA | 1674789 | c.588G>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.37 | isoniazid | |
ethionamide | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674822 | c.621C>G | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674864 | c.663C>T | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1674888 | c.687C>G | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.41 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.41 | isoniazid | |
ethionamide | ||||||
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.24 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834081 | c.540C>T | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.47 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.47 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.44 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.43 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834859 | p.Ala440Thr | missense_variant | 0.75 | pyrazinamide | Uncertain significance |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.54 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.55 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.62 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.62 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.71 | linezolid | |
tsnR | 1853423 | c.-183C>T | upstream_gene_variant | 0.71 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.69 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.68 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.66 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.58 | linezolid | |
tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.6 | linezolid | |
tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 0.59 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.63 | linezolid | |
tsnR | 1853481 | c.-125A>G | upstream_gene_variant | 0.63 | linezolid | |
tsnR | 1853484 | c.-122_-120delAGCinsGCG | upstream_gene_variant | 0.62 | linezolid | |
tsnR | 1853495 | c.-111G>C | upstream_gene_variant | 0.62 | linezolid | |
tsnR | 1853498 | c.-108G>C | upstream_gene_variant | 0.64 | linezolid | |
tsnR | 1853517 | c.-89G>A | upstream_gene_variant | 0.57 | linezolid | |
tsnR | 1853525 | c.-81G>C | upstream_gene_variant | 0.53 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917908 | c.-32C>G | upstream_gene_variant | 0.23 | capreomycin | |
tlyA | 1917929 | c.-11T>C | upstream_gene_variant | 0.29 | capreomycin | |
tlyA | 1917937 | c.-3_-2insC | upstream_gene_variant | 0.3 | capreomycin | |
tlyA | 1917940 | p.Val1Met | missense_variant | 0.29 | capreomycin | |
tlyA | 1917943 | p.Ala2Ser | missense_variant | 0.27 | capreomycin | |
tlyA | 1917951 | c.12T>C | synonymous_variant | 0.32 | capreomycin | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1917975 | c.36C>G | synonymous_variant | 0.46 | capreomycin | |
tlyA | 1917981 | c.42G>C | synonymous_variant | 0.48 | capreomycin | |
tlyA | 1917990 | c.51G>C | synonymous_variant | 0.55 | capreomycin | |
tlyA | 1917993 | c.54A>G | synonymous_variant | 0.55 | capreomycin | Not assoc w R - Interim |
tlyA | 1917996 | c.57A>G | synonymous_variant | 0.55 | capreomycin | |
tlyA | 1918002 | c.63A>G | synonymous_variant | 0.57 | capreomycin | |
tlyA | 1918036 | p.Arg33Ser | missense_variant | 0.67 | capreomycin | |
tlyA | 1918048 | p.Leu37Met | missense_variant | 0.64 | capreomycin | |
tlyA | 1918053 | c.114G>C | synonymous_variant | 0.54 | capreomycin | |
tlyA | 1918057 | p.Val40Arg | missense_variant | 0.52 | capreomycin | |
tlyA | 1918065 | c.126G>C | synonymous_variant | 0.43 | capreomycin | |
tlyA | 1918067 | p.Ala43Gly | missense_variant | 0.42 | capreomycin | |
tlyA | 1918077 | c.138G>C | synonymous_variant | 0.4 | capreomycin | |
tlyA | 1918078 | p.Ser47Ala | missense_variant | 0.4 | capreomycin | |
tlyA | 1918082 | p.Asp48Val | missense_variant | 0.4 | capreomycin | |
tlyA | 1918087 | p.Thr50Ala | missense_variant | 0.4 | capreomycin | |
tlyA | 1918092 | c.153G>C | synonymous_variant | 0.41 | capreomycin | |
tlyA | 1918103 | p.Val55Ala | missense_variant | 0.37 | capreomycin | |
tlyA | 1918137 | c.198A>C | synonymous_variant | 0.3 | capreomycin | |
tlyA | 1918197 | c.258T>C | synonymous_variant | 0.38 | capreomycin | |
tlyA | 1918206 | c.267G>C | synonymous_variant | 0.36 | capreomycin | |
tlyA | 1918212 | c.273A>G | synonymous_variant | 0.35 | capreomycin | |
tlyA | 1918218 | c.279C>G | synonymous_variant | 0.33 | capreomycin | |
tlyA | 1918221 | c.282T>C | synonymous_variant | 0.31 | capreomycin | |
tlyA | 1918224 | c.285G>C | synonymous_variant | 0.31 | capreomycin | |
tlyA | 1918236 | c.297A>C | synonymous_variant | 0.42 | capreomycin | |
tlyA | 1918248 | c.309T>C | synonymous_variant | 0.38 | capreomycin | |
tlyA | 1918251 | c.312T>G | synonymous_variant | 0.39 | capreomycin | |
tlyA | 1918258 | p.His107Glu | missense_variant | 0.42 | capreomycin | |
tlyA | 1918271 | p.Ala111Val | missense_variant | 0.32 | capreomycin | |
tlyA | 1918275 | c.336T>C | synonymous_variant | 0.29 | capreomycin | |
tlyA | 1918278 | c.339C>G | synonymous_variant | 0.3 | capreomycin | |
tlyA | 1918310 | p.Asn124Ser | missense_variant | 0.4 | capreomycin | |
tlyA | 1918315 | p.Pro126Ala | missense_variant | 0.4 | capreomycin | |
tlyA | 1918323 | c.384G>C | synonymous_variant | 0.38 | capreomycin | |
tlyA | 1918326 | c.387G>C | synonymous_variant | 0.36 | capreomycin | |
tlyA | 1918330 | p.Leu131Val | missense_variant | 0.35 | capreomycin | |
tlyA | 1918346 | p.Ala136Val | missense_variant | 0.31 | capreomycin | |
tlyA | 1918352 | p.Gly138Asp | missense_variant | 0.29 | capreomycin | |
tlyA | 1918356 | c.417C>G | synonymous_variant | 0.3 | capreomycin | |
tlyA | 1918359 | c.420A>G | synonymous_variant | 0.29 | capreomycin | |
tlyA | 1918362 | c.423G>C | synonymous_variant | 0.32 | capreomycin | |
bacA | 2063157 | c.1572C>G | synonymous_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.53 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.49 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101783 | c.1260T>G | synonymous_variant | 0.44 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101804 | c.1239T>G | synonymous_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101808 | p.Thr412Ser | missense_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101830 | p.Ile405Val | missense_variant | 0.64 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101837 | p.Ala402Val | missense_variant | 0.62 | isoniazid | Uncertain significance |
delamanid | ||||||
ethionamide | Uncertain significance | |||||
ndh | 2101858 | p.LeuIle394PheAla | missense_variant | 0.55 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101872 | p.Ile391Phe | missense_variant | 0.58 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101873 | p.Phe390Leu | missense_variant | 0.58 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101885 | c.1158G>A | synonymous_variant | 0.59 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101888 | c.1155T>C | synonymous_variant | 0.59 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101894 | c.1149T>G | synonymous_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 0.66 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 0.7 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.7 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101939 | c.1104A>G | synonymous_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101988 | p.Ala352Asp | missense_variant | 0.52 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101990 | c.1053G>C | synonymous_variant | 0.52 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101993 | c.1050A>G | synonymous_variant | 0.52 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2103173 | c.-132delG | upstream_gene_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155503 | c.609C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155691 | c.421T>C | synonymous_variant | 0.28 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 0.29 | isoniazid | |
katG | 2155704 | c.408C>G | synonymous_variant | 0.3 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.28 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.28 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.26 | isoniazid | |
katG | 2155740 | p.Gly124Gln | missense_variant | 0.24 | isoniazid | |
katG | 2155743 | c.369G>C | synonymous_variant | 0.24 | isoniazid | |
katG | 2156025 | c.87C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
PPE35 | 2168011 | p.Ser868Arg | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
PPE35 | 2168319 | p.Thr765Ile | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
PPE35 | 2168814 | c.1798dupA | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.59 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.41 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.41 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.34 | isoniazid | |
kasA | 2518121 | p.Gln3Lys | missense_variant | 0.32 | isoniazid | |
kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518138 | c.24T>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518468 | c.354A>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518474 | c.360G>A | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518483 | c.369C>G | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.35 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.33 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.42 | isoniazid | |
kasA | 2518624 | c.510C>G | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518639 | c.525G>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.62 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.61 | isoniazid | |
kasA | 2518693 | c.579C>G | synonymous_variant | 0.59 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.61 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.62 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.62 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.64 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.66 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.67 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.67 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.67 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.63 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.6 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.59 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.55 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.51 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.5 | isoniazid | |
kasA | 2518921 | c.807T>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518927 | c.813C>G | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518936 | c.822C>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518939 | c.825T>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518942 | c.828T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518951 | c.837G>C | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518954 | c.840C>G | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518963 | c.849T>C | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518969 | c.855T>G | synonymous_variant | 0.54 | isoniazid | |
kasA | 2518975 | c.861C>G | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518979 | c.865A>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518990 | c.876T>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518993 | c.879C>G | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518999 | c.885G>A | synonymous_variant | 0.45 | isoniazid | |
kasA | 2519008 | c.894C>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2519017 | c.903G>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2519020 | c.906G>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2519021 | p.Ala303Lys | missense_variant | 0.47 | isoniazid | |
kasA | 2519027 | p.Ile305Val | missense_variant | 0.48 | isoniazid | |
kasA | 2519050 | c.936C>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2519053 | c.939G>C | synonymous_variant | 0.46 | isoniazid | |
kasA | 2519062 | c.948T>G | synonymous_variant | 0.49 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.53 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.51 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2519108 | p.Asp332Gln | missense_variant | 0.43 | isoniazid | |
kasA | 2519116 | c.1002C>G | synonymous_variant | 0.45 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.39 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.39 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.38 | isoniazid | |
kasA | 2519196 | p.Thr361Ser | missense_variant | 0.24 | isoniazid | |
eis | 2715125 | p.Thr70Ala | missense_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
folC | 2747355 | p.Val82Ile | missense_variant | 0.45 | para-aminosalicylic_acid | |
folC | 2747362 | c.237G>C | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
Rv2477c | 2782807 | p.Tyr412His | missense_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782816 | c.1227T>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782822 | c.1221G>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782828 | c.1215T>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782841 | p.Thr401Asn | missense_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782847 | p.Arg399Lys | missense_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782852 | c.1191T>C | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.35 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.54 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.53 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.56 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.5 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.47 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||