TB-Profiler result

Run: SRR11342642
Summary

Run ID: SRR11342642

Sample name:

Date: 2024-04-15T02:41:23.628529

Number of reads: 4010699

Percentage reads mapped: 65.92

Median coverage: 80.0

Strain: lineage4.1.1.1

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1 Euro-American None 1.0
lineage4.1.1.1 Euro-American (X-type) RD183 0.92
lineage4 Euro-American None 1.0
lineage4.1.1 Euro-American (X-type) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Leu430Pro Assoc w R
p.Ser441Ala Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.Ser450Asn Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.Leu464Met Mutation from literature
isoniazid inhA c.-777C>T Assoc w R Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
ethambutol embB p.Gln497Arg Assoc w R
pyrazinamide
streptomycin rrs n.888G>A Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
cycloserine
ethionamide inhA c.-777C>T Assoc w R Alias fabG1_c.-15C>T
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761095 p.Leu430Pro missense_variant 0.24 rifampicin Assoc w R
rpoB 761127 p.Ser441Ala missense_variant 0.88 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761154 p.Ser450Asn missense_variant 0.71 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761196 p.Leu464Met missense_variant 0.55 rifampicin Mutation from literature
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.18 amikacin Uncertain significance Mutation from literature
kanamycin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
inhA 1673425 c.-777C>T upstream_gene_variant 1.0 isoniazid Assoc w R Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
ethionamide Assoc w R Alias fabG1_c.-15C>T
embB 4248003 p.Gln497Arg missense_variant 1.0 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6184 c.945C>A synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491342 p.Arg187His missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
Rv0565c 657269 p.Ser68Pro missense_variant 1.0 ethionamide Uncertain significance
rpoB 760997 c.1191G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.26 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761031 c.1225_1227delCAGinsAC frameshift_variant&missense_variant 0.3 rifampicin
rpoB 761037 c.1231_1233delTTGinsCC frameshift_variant&missense_variant 0.42 rifampicin
rpoB 761054 c.1248G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761058 p.Val418Thr missense_variant 0.6 rifampicin
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.69 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.81 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761159 c.1353G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761193 p.Gly463Ser missense_variant 0.37 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.31 rifampicin
rpoB 761217 c.1411_1413delCCGinsAC frameshift_variant&missense_variant 0.29 rifampicin
rpoB 761534 c.1728G>C synonymous_variant 0.18 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761557 p.Ala584Gly missense_variant 0.16 rifampicin Uncertain significance
rpoB 761565 c.1759_1761delATGinsCC frameshift_variant&missense_variant 0.16 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.24 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.28 rifampicin
rpoB 761642 c.1836G>C synonymous_variant 0.21 rifampicin
rpoB 761643 p.Val613Ile missense_variant 0.21 rifampicin Uncertain significance
rpoB 761648 c.1842T>C synonymous_variant 0.16 rifampicin
rpoB 761649 p.Ser615Pro missense_variant 0.21 rifampicin
rpoB 761654 p.Glu616Asp missense_variant 0.22 rifampicin
rpoB 761961 c.2155_2157delCCGinsAC frameshift_variant&missense_variant 0.16 rifampicin
rpoB 761974 p.His723Leu missense_variant 0.26 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.18 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.27 rifampicin
rpoB 762009 p.Leu735Val missense_variant 0.29 rifampicin
rpoB 762016 p.Glu737Ala missense_variant 0.15 rifampicin
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 0.36 rifampicin
rpoB 762051 c.2245_2247delCATinsTC frameshift_variant&missense_variant 0.29 rifampicin
rpoB 762057 p.Ile751Val missense_variant 0.44 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762071 p.Asp755Glu missense_variant 0.39 rifampicin
rpoB 762080 c.2274G>C synonymous_variant 0.45 rifampicin
rpoB 762085 p.Ala760Glu missense_variant 0.48 rifampicin
rpoB 762089 c.2283G>A synonymous_variant 0.52 rifampicin
rpoB 762110 c.2304G>C synonymous_variant 0.61 rifampicin
rpoB 762114 p.Ile770Val missense_variant 0.6 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 0.61 rifampicin
rpoB 762125 c.2319G>A synonymous_variant 0.55 rifampicin
rpoB 762126 p.Val774Ser missense_variant 0.57 rifampicin
rpoB 762134 c.2328C>T synonymous_variant 0.61 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.67 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 0.65 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762177 p.Arg791Thr missense_variant 0.64 rifampicin
rpoB 762181 p.Asp792Ala missense_variant 0.7 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762200 c.2394C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.59 rifampicin
rpoB 762236 c.2430G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.53 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 0.29 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.33 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762855 p.Val1017Ile missense_variant 0.74 rifampicin
rpoB 762858 p.Thr1018Ser missense_variant 0.75 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 0.72 rifampicin
rpoB 762871 p.Met1022Thr missense_variant 0.69 rifampicin
rpoB 762878 p.Ile1024Met missense_variant 0.67 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.79 rifampicin
rpoB 762887 c.3081G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.77 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 0.79 rifampicin
rpoB 762968 c.3162G>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.87 rifampicin
rpoC 762980 c.-390T>C upstream_gene_variant 0.82 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.9 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.88 rifampicin
rpoB 763014 p.Met1070Leu missense_variant 0.82 rifampicin
rpoB 763017 c.3211_3213delCAGinsGA frameshift_variant&missense_variant 0.85 rifampicin
rpoC 763022 c.-348C>T upstream_gene_variant 0.56 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.84 rifampicin Not assoc w R
rpoB 763038 p.Thr1078Ala missense_variant 0.84 rifampicin
rpoC 763043 c.-327G>C upstream_gene_variant 0.84 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.58 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763077 p.Val1091Thr missense_variant 0.78 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.62 rifampicin
rpoC 763109 c.-261C>T upstream_gene_variant 0.42 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 763119 p.Asn1105Asp missense_variant 0.4 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.24 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.21 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.35 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.4 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.47 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.47 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.26 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.46 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 0.6 rifampicin
rpoC 763585 c.216C>G synonymous_variant 0.22 rifampicin
rpoC 763589 p.Ile74Val missense_variant 0.29 rifampicin
rpoC 763598 p.Arg77Lys missense_variant 0.17 rifampicin
rpoC 763603 c.234C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>A synonymous_variant 0.32 rifampicin
rpoC 763609 c.240C>G synonymous_variant 0.2 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.48 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.75 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.23 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763647 p.Gly93Ala missense_variant 0.2 rifampicin
rpoC 763654 c.285C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763655 c.286_288delGAGinsAC frameshift_variant&missense_variant 0.4 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763663 c.294C>A synonymous_variant 0.2 rifampicin
rpoC 763666 c.297G>T synonymous_variant 0.51 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>A synonymous_variant 0.26 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.49 rifampicin
rpoC 763702 c.333C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>A synonymous_variant 0.18 rifampicin
rpoC 763708 c.339G>C synonymous_variant 0.78 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763718 p.Leu117Val missense_variant 0.45 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.64 rifampicin
rpoC 763724 c.355_357delGACinsAT frameshift_variant&missense_variant 0.63 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.43 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.55 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.64 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.51 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.81 rifampicin
rpoC 763772 p.Val135Met missense_variant 0.78 rifampicin
rpoC 763781 p.Ser138Glu missense_variant 0.57 rifampicin
rpoC 764359 c.990C>G synonymous_variant 0.26 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.24 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.27 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.26 rifampicin
rpoC 764424 p.Asn352Thr missense_variant 0.25 rifampicin
rpoC 764428 c.1059G>A synonymous_variant 0.26 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.28 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.27 rifampicin
rpoC 764446 p.Asp359Glu missense_variant 0.3 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.24 rifampicin
rpoC 764455 c.1086G>C synonymous_variant 0.32 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.8 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.81 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>T synonymous_variant 0.88 rifampicin
rpoC 764509 c.1140G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764512 c.1143G>C synonymous_variant 0.81 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.25 rifampicin
rpoC 764530 c.1161C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.92 rifampicin
rpoC 764543 c.1174_1176delACCinsGG frameshift_variant&missense_variant 0.87 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 0.49 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764573 c.1204_1206delCTTinsAC frameshift_variant&missense_variant 0.88 rifampicin
rpoC 764578 c.1209C>G synonymous_variant 0.87 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.98 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.98 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.86 rifampicin
rpoC 764605 c.1236G>T synonymous_variant 0.95 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.76 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.61 rifampicin
rpoC 764656 c.1287C>G synonymous_variant 0.3 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.53 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764665 c.1296C>T synonymous_variant 0.3 rifampicin
rpoC 764677 c.1308C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764678 p.Lys437Gln missense_variant 0.77 rifampicin
rpoC 764692 c.1323C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764706 p.Leu446Gln missense_variant 0.88 rifampicin Uncertain significance
rpoC 764713 c.1344G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764731 c.1362G>C synonymous_variant 0.82 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.76 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 0.67 rifampicin
rpoC 764752 c.1383G>T synonymous_variant 0.25 rifampicin
rpoC 764755 p.Asp462Glu missense_variant 0.29 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764762 c.1393_1395delCATinsTC frameshift_variant&missense_variant 0.21 rifampicin
rpoC 764774 p.Ile469Val missense_variant 0.17 rifampicin
rpoC 764780 p.Ser471Ala missense_variant 0.23 rifampicin
rpoC 764793 p.Met475Lys missense_variant 0.2 rifampicin
rpoC 765150 p.Gly594Glu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765937 c.2568T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593T>C synonymous_variant 0.16 rifampicin
rpoC 765988 c.2619G>C synonymous_variant 0.16 rifampicin
rpoC 765991 c.2622C>G synonymous_variant 0.16 rifampicin
rpoC 766003 c.2634G>C synonymous_variant 0.17 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781760 c.201T>C synonymous_variant 0.25 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.24 streptomycin Not assoc w R - Interim
rpsL 781796 p.Met79Ile missense_variant 0.28 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.28 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.23 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.24 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.25 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.23 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.19 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>T synonymous_variant 0.19 streptomycin
rpsL 781845 p.Lys96Arg missense_variant 0.16 streptomycin
rpsL 781851 p.Ile98Val missense_variant 0.17 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.17 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.15 streptomycin
rplC 800219 c.-590T>C upstream_gene_variant 1.0 linezolid
Rv1129c 1254598 c.-65dupA upstream_gene_variant 0.99 moxifloxacin
levofloxacin
rifampicin
isoniazid
rrs 1471659 n.-187C>T upstream_gene_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.16 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472296 n.451_470delAGGTCCGGGTTCTCTCGGATinsGGCGAAAG non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.34 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.36 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472670 n.825_838delGGGTTTCCTTCCTTinsTGGGTCCTTTCC non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472687 n.842_844delATCinsTTT non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.51 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472892 n.1047T>C non_coding_transcript_exon_variant 0.15 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.56 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.33 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.78 streptomycin Not assoc w R
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443_1455delCTCGGGAGGGAGCinsACGTTTGTGGGGGGAGT non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473288 n.1443_1455delCTCGGGAGGGAGCinsGTTTTTGCGGGGGGAGT non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.16 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473718 n.61G>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1473721 n.64G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1473722 n.65G>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473744 n.87T>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1473746 n.89T>A non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473747 n.90C>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1473751 n.94C>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473753 n.96A>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474156 n.499G>A non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474201 n.545delT non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.545T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474201 n.545delT non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.545T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474288 n.631_651delCCTTTTCCTCTCCGGAGGAGGinsTGT non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474326 n.669T>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474363 n.706A>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474365 n.708G>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1474384 n.727C>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474414 n.757_778delCCCACACGCGCATACGCGCGTGinsT non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474483 n.826C>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474551 n.894G>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474674 n.1017_1018delACinsG non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096_1097delACinsT non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096_1097delACinsT non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.6 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474946 n.1289C>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475016 n.1359C>T non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475018 n.1361G>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475026 n.1369G>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475034 n.1377G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475076 n.1419_1422delCCTTinsACCCTA non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475076 n.1419_1422delCCTTinsGCCCTA non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475188 n.1531C>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475194 n.1537C>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475576 n.1919C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475591 n.1934G>T non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1475596 n.1939G>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid Uncertain significance
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475760 n.2103_2108delCCGCAAinsACCCCCCTG non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475760 n.2103_2107delCCGCA non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475760 n.2103_2108delCCGCAAinsACCCCCCTG non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475760 n.2103_2107delCCGCA non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid Uncertain significance
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1475992 n.2335T>G non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475998 n.2341C>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid Uncertain significance
rrl 1475999 n.2342G>A non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.21 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid Uncertain significance
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.15 capreomycin
linezolid
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.51 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.81 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.79 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 0.49 pyrazinamide
rpsA 1833667 c.126C>T synonymous_variant 0.48 pyrazinamide
rpsA 1833668 p.Ile43Val missense_variant 0.56 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.57 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833684 p.Arg48His missense_variant 0.31 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 0.2 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.62 pyrazinamide
rpsA 1833700 c.159C>T synonymous_variant 0.28 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.42 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.21 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.58 pyrazinamide
rpsA 1833732 p.Pro64Leu missense_variant 0.6 pyrazinamide
rpsA 1833734 c.193_195delGCCinsTT frameshift_variant&missense_variant 0.39 pyrazinamide Uncertain significance
rpsA 1833742 c.201A>G synonymous_variant 0.6 pyrazinamide
rpsA 1833757 c.216C>T synonymous_variant 0.17 pyrazinamide
rpsA 1833764 p.Asp75Asn missense_variant 0.32 pyrazinamide
rpsA 1833770 p.Asn77Asp missense_variant 0.6 pyrazinamide
rpsA 1833775 p.Glu78Asp missense_variant 0.26 pyrazinamide
rpsA 1833776 p.Val79Ile missense_variant 0.32 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.36 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.29 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.34 pyrazinamide Uncertain significance
rpsA 1833808 c.267G>C synonymous_variant 0.15 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.26 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.36 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.33 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.4 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.41 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.41 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.41 pyrazinamide
rpsA 1833926 c.385_387delACGinsTC frameshift_variant&missense_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833943 c.402C>T synonymous_variant 0.18 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.5 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.29 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.4 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.35 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.56 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.9 pyrazinamide
rpsA 1833985 c.444G>A synonymous_variant 0.23 pyrazinamide
rpsA 1833991 c.450C>T synonymous_variant 0.28 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.89 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834000 c.459G>T synonymous_variant 0.34 pyrazinamide
rpsA 1834003 c.462G>A synonymous_variant 0.24 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.75 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834015 c.474G>A synonymous_variant 0.27 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.58 pyrazinamide
rpsA 1834024 p.Gln162Glu missense_variant 0.5 pyrazinamide
rpsA 1834024 c.483G>T synonymous_variant 0.32 pyrazinamide
rpsA 1834034 c.493_495delATCinsGT frameshift_variant&missense_variant 0.39 pyrazinamide Uncertain significance
rpsA 1834039 c.498C>T synonymous_variant 0.47 pyrazinamide
rpsA 1834040 p.Lys167Arg missense_variant 0.88 pyrazinamide
rpsA 1834046 c.505_507delATCinsCA frameshift_variant&missense_variant 0.39 pyrazinamide Uncertain significance
rpsA 1834051 c.510G>A synonymous_variant 0.49 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.54 pyrazinamide
rpsA 1834066 c.525G>A synonymous_variant 0.23 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.19 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834108 c.567C>A synonymous_variant 0.26 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834183 c.642T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>T synonymous_variant 0.33 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.3 pyrazinamide
rpsA 1834225 c.684C>T synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
rpsA 1834228 c.687C>T synonymous_variant 0.35 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.68 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.83 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.76 pyrazinamide Uncertain significance
rpsA 1834312 c.771G>A synonymous_variant 0.73 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.72 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.59 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834366 c.825A>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.53 pyrazinamide
rpsA 1834398 p.His286Pro missense_variant 0.4 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834435 c.894G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.3 pyrazinamide
rpsA 1834456 c.915T>C synonymous_variant 0.16 pyrazinamide
rpsA 1834459 c.918G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.31 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.21 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.45 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.3 pyrazinamide
rpsA 1834504 c.963G>T synonymous_variant 0.34 pyrazinamide
rpsA 1834523 p.Glu328Gln missense_variant 0.49 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834546 p.Asp335Glu missense_variant 0.41 pyrazinamide
rpsA 1834548 c.1011_1013delGGT disruptive_inframe_deletion 0.35 pyrazinamide
rpsA 1834558 c.1017_1018insAAG conservative_inframe_insertion 0.39 pyrazinamide
rpsA 1834564 c.1023C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
rpsA 1834570 p.Asp343Glu missense_variant 0.39 pyrazinamide
rpsA 1834572 p.Ala344Val missense_variant 0.39 pyrazinamide
rpsA 1834574 c.1033_1035delATGinsTC frameshift_variant&missense_variant 0.38 pyrazinamide Uncertain significance
rpsA 1834603 p.Glu354Asp missense_variant 0.24 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.18 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.19 pyrazinamide
tsnR 1853629 c.24G>A synonymous_variant 1.0 linezolid Not assoc w R - Interim
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2154967 p.Leu382Arg missense_variant 1.0 isoniazid Uncertain significance
Rv1979c 2222924 p.Tyr81Asp missense_variant 0.98 clofazimine Uncertain significance
bedaquiline
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
fbiA 3641447 p.Thr302Met missense_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Uncertain significance
rpoA 3877553 p.Glu319Lys missense_variant 1.0 rifampicin Not assoc w R
clpC1 4038245 c.2460C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038744 p.Thr654Lys missense_variant 0.19 pyrazinamide
clpC1 4038752 c.1953G>A synonymous_variant 0.2 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.22 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.2 pyrazinamide
clpC1 4038767 p.Arg646His missense_variant 0.22 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038776 p.Glu643Asp missense_variant 0.23 pyrazinamide
clpC1 4038793 c.1912C>T synonymous_variant 0.28 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 0.28 pyrazinamide
clpC1 4038801 p.Tyr635Phe missense_variant 0.31 pyrazinamide
clpC1 4038806 p.Glu633Asp missense_variant 0.3 pyrazinamide
clpC1 4038810 p.Gln632Pro missense_variant 0.32 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.32 pyrazinamide
clpC1 4038821 c.1884G>A synonymous_variant 0.32 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.39 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4038869 c.1836G>A synonymous_variant 0.34 pyrazinamide
clpC1 4038878 c.1825_1827delCAAinsGG frameshift_variant&missense_variant 0.28 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.17 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.18 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.16 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039709 c.996C>T synonymous_variant 0.18 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.24 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.38 pyrazinamide
clpC1 4039730 c.975C>G synonymous_variant 0.27 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.27 pyrazinamide
clpC1 4039739 c.966C>A synonymous_variant 0.22 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.29 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.25 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.31 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039763 c.942C>A synonymous_variant 0.18 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.26 pyrazinamide
clpC1 4039773 p.Lys311Met missense_variant 0.24 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.19 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039787 c.918G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039793 c.912C>T synonymous_variant 0.2 pyrazinamide
clpC1 4039811 c.894C>A synonymous_variant 0.19 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.22 pyrazinamide
clpC1 4039929 p.Ser259Thr missense_variant 0.17 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.18 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039964 c.741C>G synonymous_variant 0.19 pyrazinamide
clpC1 4039967 p.Gln246His missense_variant 0.19 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 0.2 pyrazinamide
clpC1 4040009 c.696C>T synonymous_variant 0.23 pyrazinamide
clpC1 4040015 c.690G>A synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.37 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 0.26 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.38 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 0.29 pyrazinamide
clpC1 4040060 c.645C>T synonymous_variant 0.25 pyrazinamide
clpC1 4040069 c.636G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040084 c.621C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4040096 c.609G>C synonymous_variant 0.4 pyrazinamide
clpC1 4040108 c.597G>C synonymous_variant 0.25 pyrazinamide
clpC1 4040111 c.594G>A synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040114 p.Ile197Met missense_variant 0.41 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.42 pyrazinamide
clpC1 4040123 c.580_582delGAGinsCC frameshift_variant&missense_variant 0.26 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242803 p.Val981Leu missense_variant 1.0 ethambutol Not assoc w R
embB 4249408 c.2895G>A synonymous_variant 1.0 ethambutol Not assoc w R
ethA 4326047 p.Glu476Ala missense_variant 1.0 ethionamide
whiB6 4338439 c.82dupG frameshift_variant 1.0 capreomycin Uncertain significance
amikacin Uncertain significance
kanamycin Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin