TB-Profiler result

Run: SRR11342660
Summary

Run ID: SRR11342660

Sample name:

Date: 2024-04-15T17:05:18.382326

Number of reads: 4675342

Percentage reads mapped: 62.37

Median coverage: 79.0

Strain: lineage2.2.1

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.99
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 1.0
lineage2.2 East-Asian (Beijing) RD105;RD207 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser441Ala Assoc w R - Interim
p.Ser450Asn Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.Leu464Met Mutation from literature
isoniazid inhA c.-777C>T Assoc w R Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
p.Ile194Thr Uncertain significance Mutation from literature
ethambutol embB p.Met306Val Assoc w R
pyrazinamide pncA p.Val130Ala Mutation from literature
streptomycin rrs n.888G>A Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide inhA c.-777C>T Assoc w R Alias fabG1_c.-15C>T
p.Ile194Thr Uncertain significance Mutation from literature
ethR p.Ala95Thr Uncertain significance Mutation from literature
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761127 p.Ser441Ala missense_variant 0.95 rifampicin Assoc w R - Interim
rpoB 761154 p.Ser450Asn missense_variant 0.83 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761196 p.Leu464Met missense_variant 0.81 rifampicin Mutation from literature
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.27 amikacin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
kanamycin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.23 capreomycin Assoc w R
amikacin Assoc w R
kanamycin Assoc w R
inhA 1673425 c.-777C>T upstream_gene_variant 0.98 ethionamide Assoc w R Alias fabG1_c.-15C>T
isoniazid Assoc w R Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
inhA 1674782 p.Ile194Thr missense_variant 1.0 ethionamide Uncertain significance Mutation from literature
isoniazid Uncertain significance Mutation from literature
pncA 2288853 p.Val130Ala missense_variant 1.0 pyrazinamide Mutation from literature
embB 4247429 p.Met306Val missense_variant 0.97 ethambutol Assoc w R
ethR 4327831 p.Ala95Thr missense_variant 1.0 ethionamide Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 0.99 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13636 c.-78A>G upstream_gene_variant 1.0 isoniazid Uncertain significance
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
mshA 575907 p.Ala187Val missense_variant 0.98 ethionamide Not assoc w R
isoniazid Not assoc w R
ccsA 620625 p.Ile245Met missense_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Uncertain significance
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
rpoB 760991 c.1185G>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.88 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761031 c.1225_1227delCAGinsAC frameshift_variant&missense_variant 0.89 rifampicin
rpoB 761036 c.1230G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231_1233delTTGinsCC frameshift_variant&missense_variant 0.92 rifampicin
rpoB 761058 p.Val418Thr missense_variant 0.94 rifampicin
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.96 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 0.95 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.97 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761159 c.1353G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761175 c.1369C>T synonymous_variant 0.78 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761193 p.Gly463Ser missense_variant 0.76 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.7 rifampicin
rpoB 761217 c.1411_1413delCCGinsAC frameshift_variant&missense_variant 0.68 rifampicin
rpoB 761231 c.1425C>G synonymous_variant 0.64 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761243 c.1437G>C synonymous_variant 0.63 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761250 p.Thr482Ser missense_variant 0.16 rifampicin
rpoB 761507 c.1701G>C synonymous_variant 0.34 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 0.34 rifampicin
rpoB 761511 p.Glu569Gln missense_variant 0.39 rifampicin
rpoB 761520 p.Tyr572Leu missense_variant 0.52 rifampicin
rpoB 761534 c.1728G>C synonymous_variant 0.74 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761557 p.Ala584Gly missense_variant 0.75 rifampicin Uncertain significance
rpoB 761562 c.1756_1758delGCGinsTC frameshift_variant&missense_variant 0.75 rifampicin
rpoB 761565 c.1759_1761delATGinsCC frameshift_variant&missense_variant 0.75 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.82 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.82 rifampicin
rpoB 761642 c.1836G>C synonymous_variant 0.79 rifampicin
rpoB 761643 p.Val613Ile missense_variant 0.78 rifampicin Uncertain significance
rpoB 761648 c.1842T>C synonymous_variant 0.78 rifampicin
rpoB 761649 p.Ser615Pro missense_variant 0.78 rifampicin
rpoB 761654 p.Glu616Asp missense_variant 0.78 rifampicin
rpoB 761672 c.1866C>G synonymous_variant 0.76 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.72 rifampicin
rpoB 761683 p.Leu626Arg missense_variant 0.66 rifampicin
rpoB 761688 c.1882_1884delGCGinsAC frameshift_variant&missense_variant 0.57 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.53 rifampicin
rpoB 761694 p.Ile630Val missense_variant 0.53 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.47 rifampicin
rpoB 761712 p.Val636Leu missense_variant 0.45 rifampicin
rpoB 761717 c.1911C>G synonymous_variant 0.32 rifampicin
rpoB 761918 p.Asp704Glu missense_variant 0.15 rifampicin
rpoB 761924 p.Glu706Asp missense_variant 0.26 rifampicin
rpoB 761925 p.Met707Leu missense_variant 0.32 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.49 rifampicin
rpoB 761937 p.Lys711Gln missense_variant 0.65 rifampicin
rpoB 761945 c.2139G>C synonymous_variant 0.74 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 0.74 rifampicin
rpoB 761955 p.Ile717Phe missense_variant 0.76 rifampicin
rpoB 761961 c.2155_2157delCCGinsAC frameshift_variant&missense_variant 0.78 rifampicin
rpoB 761974 p.His723Leu missense_variant 0.82 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761997 c.2191_2193delCTGinsAC frameshift_variant&missense_variant 0.76 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.79 rifampicin
rpoB 762009 p.Leu735Val missense_variant 0.79 rifampicin
rpoB 762016 p.Glu737Ala missense_variant 0.76 rifampicin
rpoB 762024 p.Val740Met missense_variant 0.79 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762057 p.Ile751Val missense_variant 0.78 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>A synonymous_variant 0.63 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762110 c.2304G>C synonymous_variant 0.49 rifampicin
rpoB 762114 p.Ile770Val missense_variant 0.38 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 0.25 rifampicin
rpoB 762126 p.Val774Thr missense_variant 0.18 rifampicin
rpoB 762135 p.Asp777Asn missense_variant 0.23 rifampicin Uncertain significance
rpoB 762140 c.2334G>C synonymous_variant 0.28 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.52 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 0.61 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762180 p.Asp792Ser missense_variant 0.56 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762197 c.2391C>G synonymous_variant 0.59 rifampicin
rpoB 762206 c.2400C>G synonymous_variant 0.63 rifampicin
rpoB 762212 c.2406G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 0.76 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762818 c.3012C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 762842 c.-528G>C upstream_gene_variant 0.59 rifampicin
rpoC 762854 c.-516G>C upstream_gene_variant 0.65 rifampicin
rpoB 762855 p.Val1017Ile missense_variant 0.86 rifampicin
rpoB 762858 p.Thr1018Ser missense_variant 0.86 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 0.83 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.91 rifampicin
rpoB 762887 c.3081G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 762896 c.-474G>C upstream_gene_variant 0.71 rifampicin
rpoC 762926 c.-444C>G upstream_gene_variant 0.81 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762938 c.-432G>C upstream_gene_variant 0.62 rifampicin
rpoC 762944 c.-426C>T upstream_gene_variant 0.68 rifampicin
rpoC 762947 c.-423C>G upstream_gene_variant 0.22 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762968 c.3162G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.78 rifampicin
rpoC 762980 c.-390T>C upstream_gene_variant 0.23 rifampicin
rpoC 762983 c.-387C>T upstream_gene_variant 0.58 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.83 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Gly missense_variant 0.63 rifampicin Uncertain significance
rpoB 763014 p.Met1070Leu missense_variant 0.41 rifampicin
rpoB 763017 c.3211_3213delCAGinsGA frameshift_variant&missense_variant 0.65 rifampicin
rpoC 763022 c.-348C>T upstream_gene_variant 0.47 rifampicin
rpoB 763031 c.3225T>C synonymous_variant 0.95 rifampicin Not assoc w R
rpoB 763038 p.Thr1078Ala missense_variant 0.63 rifampicin
rpoC 763043 c.-327G>C upstream_gene_variant 0.55 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.41 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 763077 p.Val1091Thr missense_variant 0.5 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.38 rifampicin
rpoC 763109 c.-261C>T upstream_gene_variant 0.3 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763119 p.Asn1105Asp missense_variant 0.24 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.17 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.54 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.7 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.81 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.87 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.87 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.87 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.87 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.87 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 0.92 rifampicin
rpoC 763585 c.216C>G synonymous_variant 0.89 rifampicin
rpoC 763589 p.Ile74Val missense_variant 0.9 rifampicin
rpoC 763606 c.237C>A synonymous_variant 0.91 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.91 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.92 rifampicin Uncertain significance
rpoC 763642 c.273G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763647 p.Gly93Ala missense_variant 0.86 rifampicin
rpoC 763655 p.Glu96Lys missense_variant 0.85 rifampicin
rpoC 763660 c.291T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.88 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.77 rifampicin
rpoC 763724 p.Asp119Asn missense_variant 0.76 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.76 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.83 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.75 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.82 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763772 p.Val135Met missense_variant 0.62 rifampicin
rpoC 763775 p.Ile136Val missense_variant 0.41 rifampicin
rpoC 763781 p.Ser138Glu missense_variant 0.4 rifampicin
rpoC 763786 c.417C>G synonymous_variant 0.33 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764359 c.990C>G synonymous_variant 0.32 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.32 rifampicin
rpoC 764404 c.1035C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.38 rifampicin
rpoC 764424 p.Asn352Thr missense_variant 0.22 rifampicin
rpoC 764428 c.1059G>A synonymous_variant 0.25 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.29 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.33 rifampicin
rpoC 764446 p.Asp359Glu missense_variant 0.32 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.17 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.76 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.73 rifampicin
rpoC 764497 p.Glu376Asp missense_variant 0.55 rifampicin
rpoC 764498 p.Ser377Ala missense_variant 0.5 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.45 rifampicin
rpoC 764503 c.1134G>T synonymous_variant 0.3 rifampicin
rpoC 764509 c.1140G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764512 c.1143G>C synonymous_variant 0.28 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.67 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764543 p.Thr392Ala missense_variant 0.23 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.92 rifampicin
rpoC 764549 p.Pro394Val missense_variant 0.64 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.76 rifampicin
rpoC 764573 c.1204_1206delCTTinsAG frameshift_variant&missense_variant 0.19 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.92 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.95 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.75 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.22 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>T synonymous_variant 0.24 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.7 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.63 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.3 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.55 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.29 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>C synonymous_variant 0.58 rifampicin
rpoC 764677 c.1308C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764678 p.Lys437Gln missense_variant 0.28 rifampicin
rpoC 764683 c.1314G>C synonymous_variant 0.57 rifampicin
rpoC 764703 p.Lys445Ser missense_variant 0.5 rifampicin
rpoC 764706 p.Leu446Gln missense_variant 0.88 rifampicin Uncertain significance
rpoC 764713 c.1344G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764722 c.1353G>C synonymous_variant 0.21 rifampicin
rpoC 764731 c.1362G>C synonymous_variant 0.87 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.84 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.23 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764755 p.Asp462Glu missense_variant 0.73 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764760 p.Asn464Ser missense_variant 0.59 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>T synonymous_variant 0.71 rifampicin
rpoC 764776 c.1407C>T synonymous_variant 0.64 rifampicin
rpoC 764797 c.1428G>T synonymous_variant 0.77 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764804 p.Gln479Phe missense_variant 0.74 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.69 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764818 c.1449G>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>T synonymous_variant 0.68 rifampicin
rpoC 764830 c.1461C>G synonymous_variant 0.67 rifampicin
rpoC 764839 c.1470C>T synonymous_variant 0.62 rifampicin
rpoC 764854 c.1485G>C synonymous_variant 0.75 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>T synonymous_variant 0.59 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.76 rifampicin
rpoC 764911 c.1542A>C synonymous_variant 0.72 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.73 rifampicin Uncertain significance
rpoC 764917 c.1548G>C synonymous_variant 0.69 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 0.69 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.71 rifampicin
rpoC 764948 c.1579_1581delTTGinsCC frameshift_variant&missense_variant 0.69 rifampicin
rpoC 764956 c.1587T>C synonymous_variant 0.65 rifampicin
rpoC 764958 p.Glu530Gly missense_variant 0.68 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764998 c.1629G>C synonymous_variant 0.63 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 765011 p.Ser548Gly missense_variant 0.5 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.38 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672_1674delTTGinsCC frameshift_variant&missense_variant 0.33 rifampicin
rpoC 765047 c.1678T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765617 p.Glu750Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765892 c.2523T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765903 p.Thr845Ser missense_variant 0.5 rifampicin
rpoC 765907 c.2538G>C synonymous_variant 0.54 rifampicin
rpoC 765923 p.Asn852Ala missense_variant 0.6 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.55 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765958 c.2589C>G synonymous_variant 0.6 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.6 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765988 c.2619G>C synonymous_variant 0.6 rifampicin
rpoC 765991 c.2622C>G synonymous_variant 0.6 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.59 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.53 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.48 rifampicin
rpoC 766034 c.2665_2667delCACinsGG frameshift_variant&missense_variant 0.26 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776182 p.Asp767Asn missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R
mmpS5 778979 c.-74G>T upstream_gene_variant 1.0 clofazimine Uncertain significance
bedaquiline Not assoc w R - Interim
mmpS5 779615 c.-710C>G upstream_gene_variant 0.98 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rplC 800511 c.-298A>C upstream_gene_variant 0.23 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.26 linezolid
rplC 800520 c.-289G>T upstream_gene_variant 0.26 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.31 linezolid
rplC 800536 c.-273C>T upstream_gene_variant 0.29 linezolid
rplC 800544 c.-265_-263delGCTinsTC upstream_gene_variant 0.28 linezolid
rplC 800566 c.-242_-240delAAC upstream_gene_variant 0.32 linezolid
rplC 800576 c.-233_-229delCCGCAinsGACCCGCG upstream_gene_variant 0.3 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 0.3 linezolid
rplC 800588 c.-221C>G upstream_gene_variant 0.29 linezolid
rplC 800590 c.-219_-218delGCinsCG upstream_gene_variant 0.29 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.32 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.37 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.51 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.54 linezolid
rplC 800632 c.-177_-176delATinsTC upstream_gene_variant 0.52 linezolid
rplC 800639 c.-170C>G upstream_gene_variant 0.5 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.5 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.5 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.48 linezolid
rplC 800667 c.-142_-140delTCGinsAGC upstream_gene_variant 0.45 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.44 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.43 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.38 linezolid
rplC 800715 c.-94A>G upstream_gene_variant 0.35 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.33 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.31 linezolid
rplC 800729 c.-80G>C upstream_gene_variant 0.26 linezolid
rplC 800733 c.-76A>G upstream_gene_variant 0.26 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.24 linezolid
rplC 800742 c.-67G>T upstream_gene_variant 0.22 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
Rv1258c 1406760 c.580_581insC frameshift_variant 0.97 streptomycin Uncertain significance
isoniazid Uncertain significance
pyrazinamide Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472063 n.218C>T non_coding_transcript_exon_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.26 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472274 n.429A>G non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.19 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472295 n.451_466delAGGTCCGGGTTCTCTC non_coding_transcript_exon_variant 0.42 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472425 n.580T>C non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 0.22 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.51 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.41 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472673 n.828_838delTTTCCTTCCTTinsATCCTTTCC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472892 n.1047T>C non_coding_transcript_exon_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.19 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473001 n.1156G>C non_coding_transcript_exon_variant 0.18 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473009 n.1164T>G non_coding_transcript_exon_variant 0.17 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473020 n.1175T>C non_coding_transcript_exon_variant 0.16 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.32 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.67 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.33 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.77 streptomycin Not assoc w R
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.39 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473284 n.1439A>T non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473287 n.1442_1449delCCTCGGGAinsG non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1473718 n.61G>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1473721 n.64G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1473722 n.65G>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473744 n.87T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473746 n.89T>A non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1473747 n.90C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1473751 n.94C>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473753 n.96A>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1473782 n.125A>G non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1473783 n.126A>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154C>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1473822 n.165delAinsTG non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid Uncertain significance
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1473840 n.183A>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1473862 n.205C>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1473877 n.220G>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474201 n.545delT non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.545T>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474201 n.545delT non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.545T>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474288 n.631_651delCCTTTTCCTCTCCGGAGGAGGinsTTT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474315 n.658A>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1474384 n.727C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474406 n.749T>G non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474414 n.757_778delCCCACACGCGCATACGCGCGTGinsT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053_1060delTGGTGTAAinsCCTGGGTTGT non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096_1097delACinsG non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.2 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474951 n.1294C>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1475008 n.1351C>T non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1475016 n.1359C>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475018 n.1361G>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475026 n.1369G>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475076 n.1419_1422delCCTTinsGCCCTA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475194 n.1537C>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475515 n.1858G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1475687 n.2030C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475697 n.2040C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475762 n.2105_2106delGCinsTCCTTGT non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475762 n.2105_2106delGCinsTT non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid Uncertain significance
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid Uncertain significance
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.39 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476193 n.2536A>G non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476210 n.2553_2557delGGTGGinsTTCGC non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476210 n.2557G>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid Uncertain significance
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.39 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.75 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476600 n.2943A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476680 n.3023T>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rpsA 1833641 c.100_102delAACinsGT frameshift_variant&missense_variant 0.41 pyrazinamide Uncertain significance
rpsA 1833646 c.105T>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
rpsA 1833652 c.111C>T synonymous_variant 0.62 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.72 pyrazinamide
rpsA 1833667 c.126C>T synonymous_variant 0.75 pyrazinamide
rpsA 1833668 p.Ile43Val missense_variant 0.75 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.78 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.79 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.81 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 0.79 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.87 pyrazinamide
rpsA 1833732 p.Pro64Leu missense_variant 0.87 pyrazinamide
rpsA 1833736 c.195C>T synonymous_variant 0.87 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833770 c.229_231delAACinsGT frameshift_variant&missense_variant 0.84 pyrazinamide Uncertain significance
rpsA 1833776 p.Val79Ile missense_variant 0.82 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.83 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.68 pyrazinamide
rpsA 1833797 c.256_258delGTCinsAT frameshift_variant&missense_variant 0.72 pyrazinamide Uncertain significance
rpsA 1833808 c.267G>C synonymous_variant 0.53 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.32 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.72 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.84 pyrazinamide
rpsA 1833886 c.345C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
rpsA 1833905 p.Lys122Glu missense_variant 0.83 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.84 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.84 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.84 pyrazinamide
rpsA 1833926 c.385_387delACGinsTC frameshift_variant&missense_variant 0.82 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.92 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.7 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.73 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.95 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 0.9 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834034 c.493_495delATCinsGG frameshift_variant&missense_variant 0.79 pyrazinamide Uncertain significance
rpsA 1834040 p.Lys167Arg missense_variant 0.91 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 0.85 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.87 pyrazinamide
rpsA 1834063 c.522C>T synonymous_variant 0.78 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834140 p.Ser200Thr missense_variant 0.2 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834195 c.654G>C synonymous_variant 0.66 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.57 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.56 pyrazinamide
rpsA 1834219 c.678C>G synonymous_variant 0.56 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.58 pyrazinamide
rpsA 1834228 c.687C>T synonymous_variant 0.21 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834285 c.744G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.86 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834307 p.Asp256Asn missense_variant 0.83 pyrazinamide
rpsA 1834318 c.777C>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1834327 c.786G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 0.7 pyrazinamide
rpsA 1834340 c.799_801delATGinsTC frameshift_variant&missense_variant 0.7 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
rpsA 1834384 c.843A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834395 p.Arg285Gln missense_variant 0.78 pyrazinamide
rpsA 1834397 p.His286Ala missense_variant 0.79 pyrazinamide
rpsA 1834408 c.867C>G synonymous_variant 0.84 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.89 pyrazinamide Uncertain significance
rpsA 1834432 c.891G>T synonymous_variant 0.87 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834459 c.918G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834468 c.927A>C synonymous_variant 0.89 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.91 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834522 c.981C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834523 p.Glu328Gln missense_variant 0.9 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834546 p.Asp335Glu missense_variant 0.87 pyrazinamide
rpsA 1834552 c.1013_1015delTTG disruptive_inframe_deletion 0.84 pyrazinamide
rpsA 1834558 c.1017_1018insAAG conservative_inframe_insertion 0.84 pyrazinamide
rpsA 1834564 c.1023C>A synonymous_variant 0.81 pyrazinamide
rpsA 1834570 p.Asp343Glu missense_variant 0.83 pyrazinamide
rpsA 1834572 p.Ala344Val missense_variant 0.84 pyrazinamide
rpsA 1834574 c.1033_1035delATGinsTC frameshift_variant&missense_variant 0.84 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.66 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.66 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.59 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.27 pyrazinamide
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3626562 p.Pro18Ser missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
clpC1 4039694 c.1011G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.32 pyrazinamide
clpC1 4039730 c.975C>G synonymous_variant 0.21 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039840 p.Leu289Met missense_variant 0.19 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.19 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.2 pyrazinamide
clpC1 4040015 p.Ala230Ser missense_variant 0.21 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.42 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.43 pyrazinamide
clpC1 4040045 c.660C>G synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>G synonymous_variant 0.61 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040066 c.639G>C synonymous_variant 0.57 pyrazinamide
clpC1 4040069 c.636G>C synonymous_variant 0.68 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040096 c.609G>C synonymous_variant 0.71 pyrazinamide
clpC1 4040110 c.595C>A synonymous_variant 0.65 pyrazinamide
clpC1 4040114 p.Ile197Met missense_variant 0.65 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.65 pyrazinamide
clpC1 4040125 p.Glu194Lys missense_variant 0.61 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.4 pyrazinamide
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
aftB 4267647 p.Asp397Gly missense_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R