Run ID: ERR4407463
Sample name:
Date: 2024-10-03T15:29:07.096545
Number of reads: 482644
Percentage reads mapped: 52.26
Median coverage: 18.0
Strain:
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.6.2 | Euro-American | RD726 | 0.96 |
La1.2.BCG | M.bovis | None | 0.06 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Leu359Ile | Uncertain significance | Mutation from literature | ||
p.Tyr384Asn | Mutation from literature | |||
p.Ala388Gly | Mutation from literature | |||
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2155168 | p.Ser315Thr | missense_variant | 0.87 | isoniazid | Assoc w R | High-level resistance |
embB | 4247448 | p.His312Arg | missense_variant | 0.35 | ethambutol | Mutation from literature | |
embB | 4247588 | p.Leu359Ile | missense_variant | 0.39 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4247663 | p.Tyr384Asn | missense_variant | 0.36 | ethambutol | Mutation from literature | |
embB | 4247676 | p.Ala388Gly | missense_variant | 0.48 | ethambutol | Mutation from literature | |
embB | 4247708 | p.Asn399Asp | missense_variant | 0.44 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 705 | c.705A>G | synonymous_variant | 0.62 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.55 | isoniazid | |
dnaA | 720 | c.720G>A | synonymous_variant | 0.6 | isoniazid | |
dnaA | 729 | c.729C>T | synonymous_variant | 0.6 | isoniazid | Not assoc w R - Interim |
dnaA | 741 | c.741T>C | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.5 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.5 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1003 | c.1003C>T | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.42 | isoniazid | Not assoc w R - Interim |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1041 | c.1041G>A | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.58 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.7 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.72 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.74 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.78 | isoniazid | |
dnaA | 1137 | c.1137C>G | synonymous_variant | 0.82 | isoniazid | |
dnaA | 1143 | c.1143G>C | synonymous_variant | 0.81 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.81 | isoniazid | |
dnaA | 1188 | c.1188G>A | synonymous_variant | 0.81 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1197 | c.1197T>C | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1218 | c.1218C>G | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.7 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.72 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.71 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.71 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.71 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.69 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.69 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.69 | isoniazid | Not assoc w R - Interim |
dnaA | 1311 | c.1311C>G | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1320 | c.1320G>C | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.65 | isoniazid | Not assoc w R - Interim |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.68 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1375 | c.1375T>C | synonymous_variant | 0.65 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 0.6 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.63 | isoniazid | |
dnaA | 1395 | c.1395G>C | synonymous_variant | 0.63 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.67 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.63 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.59 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.59 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 0.47 | isoniazid | |
gyrB | 6115 | c.876A>G | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6123 | p.Ala295Gly | missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6130 | c.891T>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6139 | c.900G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6196 | c.957C>T | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7015 | c.-287G>A | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7018 | c.-284G>A | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7075 | c.-227T>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7313 | c.12G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7317 | c.16T>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7347 | p.Glu16Gln | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.51 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7490 | c.189C>G | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>T | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>T | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>C | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7679 | c.378G>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7685 | c.384G>A | synonymous_variant | 0.68 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7688 | c.387C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7721 | c.420G>A | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7725 | c.424C>T | synonymous_variant | 0.75 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7775 | c.474C>A | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7781 | c.480G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7790 | c.489G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7796 | c.495G>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7814 | c.513C>G | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7823 | c.522G>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7853 | c.552C>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8237 | c.936A>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.49 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8276 | c.975G>A | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.53 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.7 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.69 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.73 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8387 | c.1086C>T | synonymous_variant | 0.73 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8391 | p.Tyr364His | missense_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>G | synonymous_variant | 0.76 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.74 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8405 | c.1104C>T | synonymous_variant | 0.75 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>T | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8465 | c.1164C>G | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>A | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251C>A | synonymous_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8576 | c.1275C>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8579 | c.1278C>T | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8597 | c.1296C>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318_1320delTTGinsCTA | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.65 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.68 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8730 | p.Gly477Arg | missense_variant | 0.55 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8750 | c.1449C>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Ser | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.5 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | p.Asp493Glu | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8807 | c.1506C>T | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8816 | c.1515C>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.38 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8837 | c.1536C>T | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.31 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.52 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9056 | c.1755C>G | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.77 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.72 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>G | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.71 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9152 | c.1851C>T | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.8 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 0.79 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.78 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.78 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.7 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13717 | c.-159T>C | upstream_gene_variant | 0.26 | isoniazid | |
Rv0010c | 13834 | c.-276A>C | upstream_gene_variant | 0.24 | isoniazid | |
fgd1 | 490782 | c.-1G>C | upstream_gene_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491001 | c.219G>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491082 | c.300T>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491083 | p.Val101Ile | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491100 | c.318C>T | synonymous_variant | 0.48 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491173 | c.391C>A | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491289 | c.507C>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491302 | p.Ile174Val | missense_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491307 | c.525C>G | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491313 | c.531C>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491325 | c.543G>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 0.32 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575662 | c.315C>G | synonymous_variant | 0.42 | isoniazid | |
ethionamide | ||||||
mshA | 575665 | c.318G>A | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575674 | c.327G>C | synonymous_variant | 0.48 | isoniazid | |
ethionamide | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.52 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575701 | c.354G>A | synonymous_variant | 0.55 | isoniazid | |
ethionamide | ||||||
mshA | 575704 | c.357T>G | synonymous_variant | 0.58 | isoniazid | |
ethionamide | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.58 | isoniazid | |
ethionamide | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.7 | isoniazid | |
ethionamide | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.71 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
mshA | 575755 | c.408G>A | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
mshA | 575756 | c.409C>T | synonymous_variant | 0.8 | isoniazid | |
ethionamide | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.8 | isoniazid | |
ethionamide | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.8 | isoniazid | |
ethionamide | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.77 | isoniazid | |
ethionamide | ||||||
mshA | 575809 | c.462C>T | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.81 | isoniazid | |
ethionamide | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.79 | isoniazid | |
ethionamide | ||||||
mshA | 575833 | c.486C>G | synonymous_variant | 0.79 | isoniazid | |
ethionamide | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 0.78 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.74 | isoniazid | |
ethionamide | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.71 | isoniazid | |
ethionamide | ||||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.67 | isoniazid | |
ethionamide | ||||||
mshA | 575920 | c.573C>G | synonymous_variant | 0.63 | isoniazid | |
ethionamide | ||||||
mshA | 575924 | p.Gly193Ser | missense_variant | 0.57 | isoniazid | |
ethionamide | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.48 | isoniazid | |
ethionamide | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.43 | isoniazid | |
ethionamide | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619528 | c.-363C>G | upstream_gene_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619531 | c.-360T>C | upstream_gene_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.45 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.48 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.53 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.61 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619609 | c.-282G>C | upstream_gene_variant | 0.56 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619668 | c.-223_-222delCGinsGC | upstream_gene_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619672 | c.-219A>T | upstream_gene_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619676 | c.-215C>G | upstream_gene_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.4 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.4 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620298 | c.408G>C | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620317 | p.Val143Leu | missense_variant | 0.45 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.38 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.29 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.29 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.32 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620583 | c.693G>C | synonymous_variant | 0.46 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620586 | c.696C>G | synonymous_variant | 0.46 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620598 | c.708C>G | synonymous_variant | 0.54 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620601 | c.711C>T | synonymous_variant | 0.54 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620604 | c.714C>G | synonymous_variant | 0.54 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620607 | c.717T>C | synonymous_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620613 | c.723C>G | synonymous_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620622 | c.732G>C | synonymous_variant | 0.5 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 0.47 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620631 | c.741T>G | synonymous_variant | 0.44 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.37 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.37 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620659 | c.769_771delCGCinsAGG | synonymous_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620664 | c.774C>T | synonymous_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.41 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620688 | c.798G>C | synonymous_variant | 0.42 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620710 | p.Val274Ile | missense_variant | 0.39 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.36 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.37 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 0.44 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 0.44 | ethionamide | |
Rv0565c | 656277 | c.1194C>G | synonymous_variant | 0.43 | ethionamide | |
Rv0565c | 656383 | p.Val363Asn | missense_variant | 0.37 | ethionamide | |
Rv0565c | 656391 | c.1080C>G | synonymous_variant | 0.37 | ethionamide | |
Rv0565c | 656402 | p.Ala357Thr | missense_variant | 0.36 | ethionamide | |
Rv0565c | 656412 | c.1059T>G | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 656418 | c.1053A>G | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656423 | c.1048T>C | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656448 | p.Ile341Val | missense_variant | 0.32 | ethionamide | |
Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 656457 | c.1014T>C | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 656469 | c.1002T>C | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656475 | c.996A>G | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656484 | c.987T>C | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 656487 | c.984T>C | synonymous_variant | 0.3 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656493 | c.978C>G | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 656502 | c.969C>T | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 0.25 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.32 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.48 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.52 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.52 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.65 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.64 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.68 | ethionamide | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.53 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.53 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.59 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.55 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.61 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.61 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.72 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.71 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.71 | isoniazid | |
nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.5 | rifampicin | Uncertain significance |
nusG | 734093 | c.-161A>C | upstream_gene_variant | 0.47 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 0.47 | rifampicin | |
nusG | 734370 | c.117A>G | synonymous_variant | 0.42 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.42 | rifampicin | |
nusG | 734407 | p.Val52Ile | missense_variant | 0.4 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.5 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.55 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.56 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.58 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.57 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.59 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.65 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.65 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.72 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.73 | rifampicin | |
nusG | 734601 | c.348C>G | synonymous_variant | 0.72 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.68 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.68 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.81 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 0.79 | rifampicin | |
nusG | 734637 | c.384G>C | synonymous_variant | 0.73 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 0.73 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 0.77 | rifampicin | |
nusG | 734658 | c.405A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R |
nusG | 734661 | c.408A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
nusG | 734664 | c.411T>G | synonymous_variant | 0.73 | rifampicin | |
nusG | 734673 | c.420A>G | synonymous_variant | 0.73 | rifampicin | |
nusG | 734676 | c.423G>C | synonymous_variant | 0.73 | rifampicin | |
nusG | 734679 | c.426C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
nusG | 734680 | p.Ala143Thr | missense_variant | 0.62 | rifampicin | |
nusG | 734703 | c.450T>C | synonymous_variant | 0.6 | rifampicin | |
nusG | 734709 | c.456T>G | synonymous_variant | 0.6 | rifampicin | |
nusG | 734715 | c.462G>C | synonymous_variant | 0.6 | rifampicin | |
nusG | 734718 | c.465G>C | synonymous_variant | 0.6 | rifampicin | |
nusG | 734719 | p.Ser156Ala | missense_variant | 0.6 | rifampicin | |
nusG | 734726 | p.Arg158Lys | missense_variant | 0.59 | rifampicin | |
nusG | 734733 | c.480T>C | synonymous_variant | 0.59 | rifampicin | |
nusG | 734742 | c.489T>G | synonymous_variant | 0.5 | rifampicin | |
nusG | 734748 | c.495C>G | synonymous_variant | 0.5 | rifampicin | |
nusG | 734750 | p.Ser166Thr | missense_variant | 0.5 | rifampicin | |
nusG | 734754 | c.501G>C | synonymous_variant | 0.5 | rifampicin | |
nusG | 734757 | c.504T>C | synonymous_variant | 0.5 | rifampicin | |
nusG | 734758 | p.Ala169Thr | missense_variant | 0.5 | rifampicin | |
nusG | 734772 | c.519G>C | synonymous_variant | 0.53 | rifampicin | |
nusG | 734775 | c.522C>G | synonymous_variant | 0.53 | rifampicin | |
nusG | 734781 | c.528A>G | synonymous_variant | 0.56 | rifampicin | |
nusG | 734784 | c.531G>A | synonymous_variant | 0.56 | rifampicin | |
nusG | 734787 | c.534T>C | synonymous_variant | 0.56 | rifampicin | |
nusG | 734792 | p.Val180Ala | missense_variant | 0.56 | rifampicin | |
nusG | 734794 | p.Val181Ile | missense_variant | 0.56 | rifampicin | Uncertain significance |
nusG | 734814 | c.561G>C | synonymous_variant | 0.5 | rifampicin | |
nusG | 734826 | c.573A>C | synonymous_variant | 0.47 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760046 | c.240G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760060 | p.Tyr85Leu | missense_variant | 0.33 | rifampicin | |
rpoB | 760067 | c.261G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.61 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.63 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.59 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.56 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.53 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.48 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.5 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.58 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.58 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760715 | c.909C>G | synonymous_variant | 0.61 | rifampicin | |
rpoB | 760718 | c.912C>T | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.43 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 0.56 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.53 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.55 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760949 | c.1143C>T | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.55 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.73 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.81 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.67 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761439 | p.Asp545Lys | missense_variant | 0.44 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.44 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.44 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 761639 | c.1833G>A | synonymous_variant | 0.64 | rifampicin | |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 761720 | c.1914C>G | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.6 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.63 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.62 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.63 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.58 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.59 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.57 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.57 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.66 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.69 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.66 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.66 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.74 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.67 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.69 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.54 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.58 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 0.7 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.62 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.69 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.74 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.67 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.64 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.6 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.6 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.58 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.54 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.54 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.54 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.48 | rifampicin | |
rpoC | 762758 | c.-612G>C | upstream_gene_variant | 0.62 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.65 | rifampicin | Uncertain significance |
rpoB | 762788 | c.2982G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.65 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.65 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.67 | rifampicin | Uncertain significance |
rpoB | 762810 | p.Ala1002Ser | missense_variant | 0.5 | rifampicin | |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.5 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.53 | rifampicin | |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.63 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.72 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.67 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.58 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.56 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.56 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.57 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.47 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.47 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 763283 | c.3477T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.72 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.72 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.6 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.58 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.58 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.58 | rifampicin | |
rpoC | 763877 | c.508_510delCTAinsTTG | synonymous_variant | 0.58 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.65 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.65 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.65 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.56 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.58 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.57 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.55 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.6 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.59 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.6 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.78 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.78 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.78 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.71 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.6 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.63 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.78 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.84 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.58 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.54 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765085 | c.1716T>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.49 | rifampicin | |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.55 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.57 | rifampicin | Uncertain significance |
rpoC | 765329 | p.Ser654Gly | missense_variant | 0.57 | rifampicin | |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.76 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.73 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.68 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.7 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.73 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.71 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.85 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.85 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.8 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.81 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.81 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.73 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.71 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.47 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.47 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 766258 | c.2889T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.52 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.54 | rifampicin | |
rpoC | 766288 | c.2919C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766303 | c.2934C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.66 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.59 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.59 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.53 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.59 | rifampicin | |
rpoC | 766625 | c.3256C>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.62 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 766882 | c.3513C>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.73 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.7 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.62 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 767111 | c.3742C>T | synonymous_variant | 0.63 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.63 | rifampicin | |
rpoC | 767158 | c.3789T>G | synonymous_variant | 0.64 | rifampicin | |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.66 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 778298 | c.183G>A | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R - Interim | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.47 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.52 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.66 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.66 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.66 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.66 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.64 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.7 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.76 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.79 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.77 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.73 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.73 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.45 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.5 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.48 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.45 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.44 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.41 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.47 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.47 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.53 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.47 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.47 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.44 | linezolid | |
rplC | 800875 | p.Val23Ile | missense_variant | 0.42 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.42 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.47 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.45 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.5 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.52 | linezolid | |
rplC | 800934 | c.126C>G | synonymous_variant | 0.48 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.48 | linezolid | |
rplC | 800939 | p.Arg44Gln | missense_variant | 0.48 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 0.48 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.48 | linezolid | |
rplC | 800967 | c.159C>G | synonymous_variant | 0.52 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.52 | linezolid | Not assoc w R - Interim |
rplC | 800982 | c.174C>T | synonymous_variant | 0.41 | linezolid | |
rplC | 800985 | c.177A>G | synonymous_variant | 0.43 | linezolid | |
rplC | 801004 | p.Leu66Val | missense_variant | 0.45 | linezolid | |
rplC | 801009 | c.201A>C | synonymous_variant | 0.37 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.35 | linezolid | |
rplC | 801156 | c.348T>A | synonymous_variant | 0.38 | linezolid | |
rplC | 801168 | c.360C>G | synonymous_variant | 0.45 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.45 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.45 | linezolid | |
rplC | 801180 | c.372C>G | synonymous_variant | 0.48 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.46 | linezolid | |
rplC | 801201 | c.393C>T | synonymous_variant | 0.44 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.44 | linezolid | |
rplC | 801246 | c.438C>T | synonymous_variant | 0.46 | linezolid | |
rplC | 801249 | c.441T>C | synonymous_variant | 0.46 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.46 | linezolid | |
rplC | 801264 | c.456C>T | synonymous_variant | 0.46 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.44 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.41 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.44 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.44 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 0.44 | linezolid | |
rplC | 801285 | c.477G>C | synonymous_variant | 0.44 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.52 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.52 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.52 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.5 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.52 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.6 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.6 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.6 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.64 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.61 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.5 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.5 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.58 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.53 | linezolid | |
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303641 | c.711C>T | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303650 | c.720G>C | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303654 | c.724C>T | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303661 | p.Val244Ala | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303663 | c.733C>T | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303671 | c.741C>T | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303681 | c.751T>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303827 | c.897A>G | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303866 | p.Glu312Asp | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303977 | c.1047C>A | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303998 | c.1068T>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304008 | c.1078_1080delTTGinsCTC | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304049 | c.1119T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304085 | c.1155C>T | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304106 | c.1176G>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.72 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.72 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304671 | p.Val581Thr | missense_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.72 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.78 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.79 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.83 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.86 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.89 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.89 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.95 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.89 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.89 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.95 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.86 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.86 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.79 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.79 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.8 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.77 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.78 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.74 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.72 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.75 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.71 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305063 | c.2133G>C | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305066 | c.2136T>C | synonymous_variant | 0.63 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305069 | c.2139G>C | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305075 | c.2145T>C | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305078 | c.2148A>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305081 | c.2151G>C | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305090 | c.2160C>G | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305092 | p.Ala721Gly | missense_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305114 | c.2184T>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305117 | c.2187T>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305126 | c.2196T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305135 | c.2205C>T | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305210 | c.2280G>A | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305215 | p.Ser762Thr | missense_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305231 | c.2301C>A | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305234 | c.2304G>C | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305240 | c.2310T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305243 | c.2313T>G | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305244 | c.2314T>C | synonymous_variant | 0.35 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305252 | c.2322G>A | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305276 | c.2346G>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305279 | p.His783Gln | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305282 | c.2352T>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305297 | c.2367G>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305300 | c.2370A>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305303 | c.2373T>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305306 | c.2376A>T | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305309 | c.2379G>C | synonymous_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305310 | p.Arg794Glu | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305318 | c.2388C>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305331 | p.Glu801Asn | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305336 | c.2406T>C | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305372 | c.2442G>A | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305384 | c.2454G>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364887 | c.475_477delTTAinsCTG | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1364898 | c.486C>T | synonymous_variant | 0.42 | pyrazinamide | |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.38 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.36 | pyrazinamide | |
sigE | 1364943 | c.531C>T | synonymous_variant | 0.26 | pyrazinamide | |
sigE | 1364949 | c.537C>T | synonymous_variant | 0.26 | pyrazinamide | |
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.36 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.53 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.59 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.48 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.78 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.85 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1476108 | n.2451T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
inhA | 1673523 | c.-679G>T | upstream_gene_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1673535 | c.-667A>G | upstream_gene_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1673568 | c.-634C>G | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673580 | c.-622T>G | upstream_gene_variant | 0.65 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1673595 | c.-607A>C | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1673596 | c.-606A>G | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1673602 | c.-600C>T | upstream_gene_variant | 0.61 | isoniazid | |
ethionamide | ||||||
inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1673615 | c.-587_-586delAAinsTG | upstream_gene_variant | 0.55 | isoniazid | |
ethionamide | ||||||
inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.55 | isoniazid | |
ethionamide | ||||||
inhA | 1673633 | c.-569G>A | upstream_gene_variant | 0.55 | isoniazid | |
ethionamide | ||||||
inhA | 1673637 | c.-565C>G | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1673641 | c.-561G>A | upstream_gene_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1673646 | c.-556T>C | upstream_gene_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1673657 | c.-545C>A | upstream_gene_variant | 0.64 | isoniazid | |
ethionamide | ||||||
inhA | 1673660 | c.-542C>A | upstream_gene_variant | 0.59 | isoniazid | |
ethionamide | ||||||
inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.59 | isoniazid | |
ethionamide | ||||||
inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.65 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1673685 | c.-517C>T | upstream_gene_variant | 0.68 | isoniazid | |
ethionamide | ||||||
inhA | 1673710 | c.-492C>A | upstream_gene_variant | 0.72 | isoniazid | |
ethionamide | ||||||
inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 0.67 | isoniazid | |
ethionamide | ||||||
inhA | 1673733 | c.-469G>C | upstream_gene_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1673985 | c.-217C>A | upstream_gene_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674079 | c.-123C>G | upstream_gene_variant | 0.39 | isoniazid | |
ethionamide | ||||||
inhA | 1674114 | c.-88T>A | upstream_gene_variant | 0.35 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1674123 | c.-79T>C | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674126 | c.-76G>C | upstream_gene_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674132 | c.-70T>C | upstream_gene_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674136 | c.-66T>G | upstream_gene_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674141 | c.-61T>C | upstream_gene_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.53 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.57 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.75 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.75 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.75 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 0.73 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.73 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.79 | isoniazid | |
ethionamide | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 0.76 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.61 | isoniazid | |
ethionamide | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.71 | isoniazid | |
ethionamide | ||||||
inhA | 1674723 | c.522C>T | synonymous_variant | 0.69 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.67 | isoniazid | |
ethionamide | ||||||
inhA | 1674741 | c.540C>T | synonymous_variant | 0.64 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674750 | c.549T>C | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674753 | c.552G>C | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.6 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>G | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674789 | c.588G>C | synonymous_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.69 | isoniazid | |
ethionamide | ||||||
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.45 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.54 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834262 | c.721_723delTCGinsAGC | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.7 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.69 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.71 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.68 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.71 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.73 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.66 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.41 | pyrazinamide | |
rpsA | 1834684 | c.1143C>T | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.36 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.38 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.39 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.39 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
bacA | 2063187 | c.1542C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101804 | c.1239T>G | synonymous_variant | 0.5 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101808 | p.Thr412Ser | missense_variant | 0.53 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101830 | p.Ile405Val | missense_variant | 0.59 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101837 | p.Ala402Val | missense_variant | 0.59 | isoniazid | Uncertain significance |
delamanid | ||||||
ethionamide | Uncertain significance | |||||
ndh | 2101858 | p.LeuIle394PheAla | missense_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101872 | p.Ile391Phe | missense_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101873 | p.Phe390Leu | missense_variant | 0.62 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101885 | c.1158G>A | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101888 | c.1155T>C | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101891 | c.1152C>G | synonymous_variant | 0.57 | isoniazid | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2101894 | c.1149T>C | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101920 | c.1123A>C | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.57 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101939 | c.1104A>G | synonymous_variant | 0.5 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102710 | c.333C>T | synonymous_variant | 0.41 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102718 | p.Gln109Glu | missense_variant | 0.41 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102728 | c.315T>C | synonymous_variant | 0.41 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102736 | c.307T>C | synonymous_variant | 0.38 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102737 | p.Glu102Asp | missense_variant | 0.33 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102743 | c.300C>G | synonymous_variant | 0.35 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102750 | p.Cys98Phe | missense_variant | 0.35 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102754 | p.Gln97Lys | missense_variant | 0.35 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102755 | c.288G>C | synonymous_variant | 0.35 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102758 | c.285C>G | synonymous_variant | 0.35 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102872 | c.171A>G | synonymous_variant | 0.38 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102893 | c.150G>C | synonymous_variant | 0.35 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102899 | c.144T>C | synonymous_variant | 0.32 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102902 | c.141C>G | synonymous_variant | 0.3 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
Rv1979c | 2221746 | c.1416_1418dupCCG | disruptive_inframe_insertion | 1.0 | bedaquiline | Uncertain significance |
clofazimine | Uncertain significance | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.82 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.59 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.59 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.41 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.43 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518573 | c.459G>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.4 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.53 | isoniazid | |
kasA | 2518624 | c.510C>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518639 | c.525G>C | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.55 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.59 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518936 | c.822C>G | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518939 | c.825T>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518942 | c.828T>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518951 | c.837G>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518963 | c.849T>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518969 | c.855T>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518975 | c.861C>G | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518979 | c.865A>C | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518990 | c.876T>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518993 | c.879C>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518999 | c.885G>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2519008 | c.894C>G | synonymous_variant | 0.53 | isoniazid | |
kasA | 2519017 | c.903G>C | synonymous_variant | 0.53 | isoniazid | |
kasA | 2519020 | c.906G>C | synonymous_variant | 0.53 | isoniazid | |
kasA | 2519021 | p.Ala303Lys | missense_variant | 0.53 | isoniazid | |
kasA | 2519027 | p.Ile305Val | missense_variant | 0.57 | isoniazid | |
kasA | 2519050 | c.936C>G | synonymous_variant | 0.62 | isoniazid | |
kasA | 2519053 | c.939G>C | synonymous_variant | 0.64 | isoniazid | |
kasA | 2519056 | c.942G>C | synonymous_variant | 0.64 | isoniazid | |
kasA | 2519062 | c.948T>G | synonymous_variant | 0.64 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.64 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.64 | isoniazid | |
kasA | 2519095 | c.981C>A | synonymous_variant | 0.7 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.73 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.8 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.82 | isoniazid | |
Rv2477c | 2782894 | c.1149C>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.53 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.58 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.5 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>A | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783047 | p.Asp332Gly | missense_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.56 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.44 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783107 | c.936G>A | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.52 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.58 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.56 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.46 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.59 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.59 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.62 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783425 | p.Pro206Ala | missense_variant | 0.69 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | ||||||
Rv2477c | 2783428 | c.615C>T | synonymous_variant | 0.69 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783431 | c.610_612delAGCinsTCA | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783437 | c.606G>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783497 | c.544_546delTTGinsCTC | synonymous_variant | 0.54 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.54 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.68 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.67 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.62 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.61 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783650 | c.393C>T | synonymous_variant | 0.52 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>A | synonymous_variant | 0.48 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2681 | 2996287 | c.-452A>C | upstream_gene_variant | 0.54 | capreomycin | |
Rv2680 | 2996294 | p.Ile64Val | missense_variant | 0.54 | capreomycin | |
Rv2681 | 2996299 | c.-440G>A | upstream_gene_variant | 0.54 | capreomycin | |
Rv2680 | 2996308 | p.Glu68Asp | missense_variant | 0.58 | capreomycin | |
Rv2680 | 2996310 | p.Leu69Arg | missense_variant | 0.58 | capreomycin | |
Rv2680 | 2996314 | p.Asp70Glu | missense_variant | 0.58 | capreomycin | |
Rv2680 | 2996315 | p.Val71Ile | missense_variant | 0.58 | capreomycin | |
Rv2681 | 2996320 | c.-419T>C | upstream_gene_variant | 0.5 | capreomycin | |
Rv2681 | 2996323 | c.-416G>C | upstream_gene_variant | 0.5 | capreomycin | |
Rv2681 | 2996326 | c.-413G>A | upstream_gene_variant | 0.5 | capreomycin | |
Rv2681 | 2996329 | c.-410T>G | upstream_gene_variant | 0.5 | capreomycin | |
Rv2680 | 2996335 | p.Glu77Asp | missense_variant | 0.5 | capreomycin | |
Rv2752c | 3064860 | c.1332G>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064863 | c.1329G>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064872 | c.1320T>G | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064877 | p.Ser439Ala | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064881 | p.Ser437Ala | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064887 | c.1305A>G | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064893 | c.1299C>G | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064896 | c.1296T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064914 | c.1278T>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064926 | c.1264_1266delTTGinsCTC | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064935 | c.1257A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064941 | p.Gln417Glu | missense_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064956 | p.Ser412Arg | missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3064962 | c.1230C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3064998 | c.1194A>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065007 | c.1185G>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065018 | p.Asn392His | missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065028 | p.Val388Ile | missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065040 | c.1152C>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065048 | c.1144C>T | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065052 | c.1140G>A | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065055 | c.1137T>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065079 | c.1113T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065082 | c.1110G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065085 | c.1105_1107delAGGinsCGC | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065109 | c.1081_1083delAGAinsCGC | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065115 | c.1077C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065126 | p.Ser356Ala | missense_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065127 | c.1065G>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065130 | p.Ala354Glu | missense_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065151 | c.1041G>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065183 | p.Ser337Ala | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065186 | c.1006T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065190 | p.Ile334Val | missense_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065196 | c.996T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065202 | c.990T>G | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065205 | c.987T>C | synonymous_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065210 | c.982T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065223 | c.969T>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065229 | c.963G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065232 | c.960T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065241 | c.951A>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065262 | c.930G>A | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065268 | c.924A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065288 | c.904T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065292 | c.900T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065295 | p.Gln299Arg | missense_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3065298 | p.Asp298Glu | missense_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065306 | p.Ala296Pro | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065311 | p.Thr294Met | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065313 | c.879A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065323 | p.Ala290Gly | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065334 | p.Leu286Val | missense_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065337 | c.855T>C | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065346 | c.846T>G | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065352 | c.840A>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065355 | c.837A>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065364 | c.828G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065367 | p.Gln275Glu | missense_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065372 | c.820A>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065373 | c.819A>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065378 | p.Val272Ile | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065381 | p.Arg271Gly | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065397 | c.795G>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065400 | c.792A>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065412 | c.780G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065418 | c.774A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065421 | c.771G>A | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065442 | c.750T>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065451 | c.741G>A | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065457 | c.735A>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066066 | c.126T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066118 | p.Asn25Ser | missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066150 | c.42C>A | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066153 | p.Ser13Thr | missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066158 | p.Thr12Ala | missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3066161 | c.31C>T | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066162 | c.30C>A | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066165 | c.27T>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066176 | p.Pro6Ala | missense_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066177 | c.15T>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066196 | c.-5C>G | upstream_gene_variant | 0.44 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3066199 | c.-8G>T | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066201 | c.-10T>C | upstream_gene_variant | 0.44 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3066203 | c.-12G>A | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066205 | c.-14A>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066210 | c.-19G>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066217 | c.-37_-26delTCGGTGATCTAAinsC | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066237 | c.-46C>G | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066249 | c.-58C>T | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066261 | c.-70G>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066270 | c.-79G>A | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066276 | c.-85G>A | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066279 | c.-88A>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066282 | c.-91G>T | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066287 | c.-96G>C | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066290 | c.-99G>A | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066291 | c.-100G>A | upstream_gene_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066330 | c.-139G>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066335 | c.-144T>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066339 | c.-148G>C | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066561 | c.-370A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066618 | c.-427A>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066633 | c.-442T>C | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066638 | c.-447T>G | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066642 | c.-453_-451delTTGinsCTC | upstream_gene_variant | 0.52 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066960 | c.-769C>G | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066969 | c.-778G>C | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067355 | c.591A>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.57 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.57 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.7 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.65 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.72 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>C | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.78 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.78 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.86 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.86 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.86 | para-aminosalicylic_acid | |
thyX | 3067559 | c.387C>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.91 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067577 | c.369G>A | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067601 | p.Arg115His | missense_variant | 0.86 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 0.86 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067631 | c.315C>G | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>C | synonymous_variant | 0.81 | para-aminosalicylic_acid | |
thyX | 3067691 | p.Ile85Leu | missense_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.81 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.77 | para-aminosalicylic_acid | |
thyX | 3067736 | p.Phe70Leu | missense_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.83 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.73 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.73 | para-aminosalicylic_acid | |
thyX | 3067772 | c.174C>G | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.68 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.31 | para-aminosalicylic_acid | |
thyA | 3073812 | c.660C>G | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
thyA | 3073815 | c.657G>A | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyA | 3073824 | c.648A>G | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
thyA | 3073827 | c.645A>G | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
thyA | 3073839 | c.633T>C | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyA | 3073860 | c.612C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyA | 3073863 | c.609T>C | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyA | 3073866 | c.606C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyA | 3073872 | p.Ile200Val | missense_variant | 0.79 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.77 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 0.77 | para-aminosalicylic_acid | |
thyA | 3073917 | c.555C>G | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyA | 3073920 | c.552C>G | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyA | 3073923 | c.547_549delTTGinsCTA | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyA | 3073947 | c.525G>A | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyA | 3073956 | c.516G>C | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyA | 3074028 | c.444G>C | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyA | 3074079 | c.393G>C | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
Rv3083 | 3448567 | p.His22Asp | missense_variant | 1.0 | ethionamide | Uncertain significance |
lpqB | 3623561 | c.1350T>C | synonymous_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623570 | c.1341A>G | synonymous_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623573 | c.1336_1338delCTTinsTTG | synonymous_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623580 | p.Asn444Thr | missense_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623597 | c.1314C>G | synonymous_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623601 | p.Ser437Thr | missense_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623612 | p.Thr433Val | missense_variant | 0.45 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623630 | c.1281G>C | synonymous_variant | 0.45 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623648 | c.1263A>G | synonymous_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623654 | p.Asp419Glu | missense_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623660 | c.1251A>C | synonymous_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623669 | c.1242G>C | synonymous_variant | 0.55 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623676 | p.Val412Asn | missense_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623682 | p.Thr410Gly | missense_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623684 | c.1227T>C | synonymous_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623693 | c.1218G>C | synonymous_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623703 | p.Ala403Val | missense_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
lpqB | 3623721 | p.Ser397Thr | missense_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625087 | p.Ala509Ser | missense_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625093 | p.Glu507Asp | missense_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625099 | c.-189C>G | upstream_gene_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625117 | c.-207T>C | upstream_gene_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.59 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625135 | c.1479A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625149 | p.Val489Ile | missense_variant | 0.63 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.63 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625165 | c.-255G>C | upstream_gene_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625171 | c.-261C>G | upstream_gene_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625206 | p.Ser470Ala | missense_variant | 0.64 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625497 | c.1117T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625510 | c.-600T>C | upstream_gene_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.42 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.42 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.58 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.52 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.68 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.68 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625864 | c.-956_-954delCGTinsAGG | upstream_gene_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625876 | c.738G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626777 | c.-164C>G | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.66 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.73 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626945 | c.-332C>T | upstream_gene_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.71 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.7 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.73 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.73 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.6 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.45 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.42 | rifampicin | |
bedaquiline | ||||||
fbiB | 3640878 | c.-657T>C | upstream_gene_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3640899 | c.-636G>C | upstream_gene_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiA | 3640900 | p.Gln120Asn | missense_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3640911 | c.-624C>T | upstream_gene_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3640914 | c.-621C>G | upstream_gene_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rpoA | 3877503 | c.1005G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877507 | p.Gly334Ala | missense_variant | 0.3 | rifampicin | |
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.4 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.36 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.39 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.47 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.47 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.68 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.66 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.68 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoA | 3877923 | c.585C>T | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.75 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.75 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoA | 3878043 | c.465G>A | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3878058 | c.450G>T | synonymous_variant | 0.68 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.66 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.69 | rifampicin | |
rpoA | 3878082 | c.426T>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.71 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.69 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.61 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoA | 3878172 | c.336G>C | synonymous_variant | 0.59 | rifampicin | |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.77 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.81 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.81 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.83 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoA | 3878340 | c.168C>T | synonymous_variant | 0.77 | rifampicin | |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.77 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.74 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.72 | rifampicin | |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.4 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.55 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.55 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.55 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.61 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.64 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.68 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.68 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.76 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878860 | c.-353C>T | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.75 | rifampicin | Uncertain significance |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.83 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.83 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.83 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.7 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.7 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.72 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.71 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.79 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.83 | rifampicin | |
rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.6 | rifampicin | |
rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.57 | rifampicin | |
rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.57 | rifampicin | |
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.57 | pretomanid | |
delamanid | ||||||
ddn | 3986645 | c.-199G>A | upstream_gene_variant | 0.5 | pretomanid | |
delamanid | ||||||
ddn | 3986646 | c.-198_-196delCTCinsTTG | upstream_gene_variant | 0.48 | pretomanid | |
delamanid | ||||||
ddn | 3986665 | c.-179G>C | upstream_gene_variant | 0.41 | pretomanid | |
delamanid | ||||||
clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038308 | c.2397G>T | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4038317 | c.2388G>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>T | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>C | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.72 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.74 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.74 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.76 | pyrazinamide | |
clpC1 | 4038460 | p.Leu749Met | missense_variant | 0.76 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.7 | pyrazinamide | |
clpC1 | 4038488 | p.Ala739Gly | missense_variant | 0.7 | pyrazinamide | |
clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.66 | pyrazinamide | |
clpC1 | 4038497 | p.Ser736Gln | missense_variant | 0.66 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.62 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>T | synonymous_variant | 0.61 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.52 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.44 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.44 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>A | synonymous_variant | 0.61 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.63 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.68 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039001 | c.1704C>T | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.52 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039190 | c.1515C>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.57 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039229 | c.1476C>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.57 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.62 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.54 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.48 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039484 | c.1221T>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.56 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.53 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.71 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.74 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039982 | c.723G>A | synonymous_variant | 0.62 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.61 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4040207 | c.498T>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040210 | c.495G>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040228 | c.477G>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040276 | c.427_429delTCCinsAGT | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.56 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040444 | c.261C>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040528 | c.177G>T | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040567 | c.138C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040570 | c.135C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040573 | c.132T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040585 | c.120A>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040596 | c.109C>T | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040600 | c.103_105delTTAinsCTG | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040657 | c.48T>G | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
panD | 4044682 | c.-401C>A | upstream_gene_variant | 0.54 | pyrazinamide | |
panD | 4044688 | c.-407T>C | upstream_gene_variant | 0.54 | pyrazinamide | |
panD | 4044692 | c.-411G>C | upstream_gene_variant | 0.54 | pyrazinamide | |
panD | 4044700 | c.-419C>A | upstream_gene_variant | 0.57 | pyrazinamide | |
panD | 4044704 | c.-423G>C | upstream_gene_variant | 0.57 | pyrazinamide | |
panD | 4044712 | c.-431C>A | upstream_gene_variant | 0.53 | pyrazinamide | |
panD | 4044725 | c.-444C>T | upstream_gene_variant | 0.69 | pyrazinamide | |
panD | 4044737 | c.-456T>C | upstream_gene_variant | 0.6 | pyrazinamide | |
panD | 4044746 | c.-467_-465delGTGinsATC | upstream_gene_variant | 0.6 | pyrazinamide | |
panD | 4044752 | c.-471T>C | upstream_gene_variant | 0.6 | pyrazinamide | |
panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 0.56 | pyrazinamide | |
panD | 4044788 | c.-507G>C | upstream_gene_variant | 0.56 | pyrazinamide | |
panD | 4044791 | c.-510G>C | upstream_gene_variant | 0.56 | pyrazinamide | |
panD | 4044800 | c.-519C>G | upstream_gene_variant | 0.56 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044823 | c.-542G>C | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044833 | c.-552A>G | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044844 | c.-563T>C | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044848 | c.-567T>A | upstream_gene_variant | 0.62 | pyrazinamide | |
panD | 4044854 | c.-573A>G | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4044860 | c.-579C>G | upstream_gene_variant | 0.69 | pyrazinamide | |
panD | 4044872 | c.-591C>G | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044890 | c.-609G>C | upstream_gene_variant | 0.57 | pyrazinamide | |
panD | 4044895 | c.-614A>G | upstream_gene_variant | 0.57 | pyrazinamide | |
panD | 4044896 | c.-615T>G | upstream_gene_variant | 0.57 | pyrazinamide | |
panD | 4044902 | c.-623_-621delACGinsGCC | upstream_gene_variant | 0.59 | pyrazinamide | |
panD | 4044908 | c.-628_-627delCTinsTC | upstream_gene_variant | 0.59 | pyrazinamide | |
panD | 4044917 | c.-636G>C | upstream_gene_variant | 0.62 | pyrazinamide | |
panD | 4044926 | c.-645C>A | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4044929 | c.-648G>C | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4044935 | c.-655_-654delAAinsTG | upstream_gene_variant | 0.64 | pyrazinamide | |
panD | 4044941 | c.-660G>C | upstream_gene_variant | 0.67 | pyrazinamide | |
panD | 4044954 | c.-674_-673delCCinsAT | upstream_gene_variant | 0.67 | pyrazinamide | |
panD | 4044980 | c.-699A>G | upstream_gene_variant | 0.65 | pyrazinamide | |
panD | 4044983 | c.-702G>T | upstream_gene_variant | 0.65 | pyrazinamide | |
panD | 4044989 | c.-708T>C | upstream_gene_variant | 0.65 | pyrazinamide | |
panD | 4045000 | c.-719A>C | upstream_gene_variant | 0.62 | pyrazinamide | |
panD | 4045001 | c.-720G>C | upstream_gene_variant | 0.58 | pyrazinamide | |
panD | 4045019 | c.-738G>C | upstream_gene_variant | 0.48 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.45 | pyrazinamide | |
panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.46 | pyrazinamide | |
panD | 4045034 | c.-753A>C | upstream_gene_variant | 0.48 | pyrazinamide | |
panD | 4045055 | c.-774T>G | upstream_gene_variant | 0.41 | pyrazinamide | |
panD | 4045067 | c.-786C>G | upstream_gene_variant | 0.38 | pyrazinamide | |
panD | 4045070 | c.-789C>T | upstream_gene_variant | 0.37 | pyrazinamide | |
glpK | 4138529 | c.1227G>A | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138535 | c.1221T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138565 | c.1191G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138568 | c.1188A>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138571 | c.1185C>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138574 | c.1182G>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138580 | c.1176C>T | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138598 | c.1158G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138601 | c.1155G>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138606 | c.1150T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138607 | c.1149G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138610 | c.1146C>G | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138622 | c.1134C>G | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138625 | c.1131G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138646 | c.1110G>C | synonymous_variant | 0.66 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138679 | p.Met359Val | missense_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.7 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138763 | c.993G>A | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138774 | p.Ser328Ala | missense_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138778 | c.978C>G | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138796 | c.960A>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138802 | c.954G>A | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138808 | c.948G>T | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4240645 | c.783G>C | synonymous_variant | 0.65 | ethambutol | |
embC | 4240651 | c.789G>A | synonymous_variant | 0.79 | ethambutol | |
embC | 4240669 | c.807G>C | synonymous_variant | 0.81 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.81 | ethambutol | Not assoc w R |
embC | 4240677 | p.Gly272Ala | missense_variant | 0.72 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 0.78 | ethambutol | |
embC | 4240693 | c.831T>G | synonymous_variant | 0.81 | ethambutol | |
embC | 4240699 | c.837C>G | synonymous_variant | 0.81 | ethambutol | Not assoc w R - Interim |
embC | 4240726 | c.864G>C | synonymous_variant | 0.69 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.68 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.68 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.67 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.64 | ethambutol | |
embC | 4240828 | c.966G>A | synonymous_variant | 0.59 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.59 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.47 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.47 | ethambutol | |
embC | 4240873 | c.1011C>G | synonymous_variant | 0.47 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.41 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.41 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.39 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4241032 | c.1170G>C | synonymous_variant | 0.53 | ethambutol | |
embC | 4241038 | c.1176G>C | synonymous_variant | 0.53 | ethambutol | |
embC | 4241047 | c.1185C>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.5 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
embC | 4241449 | c.1587C>G | synonymous_variant | 0.47 | ethambutol | |
embC | 4241453 | p.Ile531Val | missense_variant | 0.47 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 0.52 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 0.41 | ethambutol | |
embC | 4241488 | c.1626G>C | synonymous_variant | 0.41 | ethambutol | |
embC | 4241496 | p.Ala545Gly | missense_variant | 0.47 | ethambutol | |
embC | 4241500 | c.1638A>C | synonymous_variant | 0.47 | ethambutol | |
embC | 4241501 | p.Ser547Thr | missense_variant | 0.47 | ethambutol | |
embC | 4241506 | c.1644G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241518 | c.1656A>G | synonymous_variant | 0.47 | ethambutol | |
embC | 4241521 | c.1659T>C | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
embC | 4241530 | c.1668C>A | synonymous_variant | 0.5 | ethambutol | |
embC | 4241536 | c.1674A>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4241539 | c.1677T>C | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embC | 4241545 | c.1683T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241551 | c.1689A>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.55 | ethambutol | |
embC | 4241572 | c.1710C>G | synonymous_variant | 0.58 | ethambutol | |
embC | 4241578 | c.1716G>C | synonymous_variant | 0.55 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241587 | c.1725C>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4241591 | p.Leu577Val | missense_variant | 0.54 | ethambutol | |
embC | 4241626 | c.1764T>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241635 | c.1773G>C | synonymous_variant | 0.47 | ethambutol | |
embC | 4241644 | c.1782G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241648 | c.1786_1788delTTGinsCTC | synonymous_variant | 0.5 | ethambutol | |
embC | 4241657 | p.Ser599Pro | missense_variant | 0.46 | ethambutol | |
embC | 4242550 | c.2688C>G | synonymous_variant | 0.79 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.77 | ethambutol | Not assoc w R |
embC | 4242710 | p.Gln950Glu | missense_variant | 0.42 | ethambutol | |
embC | 4242715 | c.2853T>C | synonymous_variant | 0.42 | ethambutol | Not assoc w R - Interim |
embA | 4242742 | c.-491C>G | upstream_gene_variant | 0.39 | ethambutol | |
embA | 4242748 | c.-485A>G | upstream_gene_variant | 0.44 | ethambutol | |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.46 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.52 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.48 | ethambutol | |
embC | 4242791 | p.Ala977Ser | missense_variant | 0.48 | ethambutol | |
embA | 4242796 | c.-437G>C | upstream_gene_variant | 0.48 | ethambutol | |
embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.48 | ethambutol | |
embA | 4242820 | c.-413G>C | upstream_gene_variant | 0.48 | ethambutol | |
embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.5 | ethambutol | |
embA | 4242832 | c.-401A>C | upstream_gene_variant | 0.48 | ethambutol | |
embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.46 | ethambutol | |
embC | 4242841 | c.2979C>T | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.44 | ethambutol | |
embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.44 | ethambutol | |
embA | 4242859 | c.-374C>T | upstream_gene_variant | 0.43 | ethambutol | |
embA | 4242862 | c.-371A>G | upstream_gene_variant | 0.43 | ethambutol | |
embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.43 | ethambutol | |
embC | 4242883 | c.3021C>G | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
embA | 4242892 | c.-341G>C | upstream_gene_variant | 0.33 | ethambutol | |
embA | 4242901 | c.-332G>C | upstream_gene_variant | 0.36 | ethambutol | |
embA | 4244516 | c.1284G>C | synonymous_variant | 0.43 | ethambutol | |
embA | 4244517 | p.Leu429Val | missense_variant | 0.43 | ethambutol | |
embA | 4244523 | p.Pro431Ala | missense_variant | 0.46 | ethambutol | |
embA | 4244534 | c.1302T>C | synonymous_variant | 0.48 | ethambutol | |
embA | 4244537 | c.1305T>G | synonymous_variant | 0.48 | ethambutol | |
embA | 4244543 | c.1311C>G | synonymous_variant | 0.52 | ethambutol | |
embA | 4244547 | p.Ile439Val | missense_variant | 0.52 | ethambutol | |
embA | 4244552 | c.1320C>G | synonymous_variant | 0.52 | ethambutol | Not assoc w R - Interim |
embA | 4244557 | p.Arg442Thr | missense_variant | 0.52 | ethambutol | |
embA | 4244567 | c.1335C>T | synonymous_variant | 0.56 | ethambutol | |
embA | 4244576 | c.1344G>A | synonymous_variant | 0.56 | ethambutol | |
embA | 4244582 | c.1350T>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4244585 | c.1353A>G | synonymous_variant | 0.58 | ethambutol | Not assoc w R - Interim |
embA | 4244611 | p.Ala460Gly | missense_variant | 0.56 | ethambutol | |
embA | 4244616 | p.Ala462Ser | missense_variant | 0.5 | ethambutol | |
embA | 4244619 | c.1387_1389delTTGinsCTC | synonymous_variant | 0.5 | ethambutol | |
embA | 4244625 | p.Leu465Val | missense_variant | 0.47 | ethambutol | |
embA | 4244631 | p.Thr467Leu | missense_variant | 0.47 | ethambutol | |
embA | 4244645 | c.1413T>C | synonymous_variant | 0.47 | ethambutol | |
embA | 4244648 | c.1416G>C | synonymous_variant | 0.47 | ethambutol | |
embA | 4244649 | p.Asp473Ser | missense_variant | 0.47 | ethambutol | |
embA | 4244670 | p.Ala480Leu | missense_variant | 0.54 | ethambutol | |
embA | 4244675 | c.1443A>G | synonymous_variant | 0.54 | ethambutol | |
embA | 4244678 | c.1446G>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4244681 | c.1449A>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4244690 | c.1458G>A | synonymous_variant | 0.54 | ethambutol | Not assoc w R - Interim |
embA | 4244702 | c.1470C>G | synonymous_variant | 0.5 | ethambutol | |
embA | 4244708 | c.1476C>G | synonymous_variant | 0.53 | ethambutol | |
embA | 4245053 | c.1821G>C | synonymous_variant | 0.4 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 0.52 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.57 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.58 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 0.58 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.56 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.56 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.61 | ethambutol | |
embA | 4245149 | c.1917C>T | synonymous_variant | 0.61 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.62 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.67 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.67 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.62 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.67 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 0.63 | ethambutol | |
embA | 4245222 | p.Tyr664Gln | missense_variant | 0.6 | ethambutol | |
embA | 4245248 | c.2016G>C | synonymous_variant | 0.59 | ethambutol | |
embA | 4245257 | c.2025A>G | synonymous_variant | 0.58 | ethambutol | |
embA | 4245263 | c.2031A>G | synonymous_variant | 0.61 | ethambutol | Not assoc w R - Interim |
embA | 4245282 | p.Ile684Val | missense_variant | 0.55 | ethambutol | |
embA | 4245285 | c.2053T>C | synonymous_variant | 0.53 | ethambutol | |
embA | 4245290 | c.2058C>G | synonymous_variant | 0.52 | ethambutol | |
embA | 4245293 | c.2061T>G | synonymous_variant | 0.52 | ethambutol | |
embA | 4245296 | c.2064G>C | synonymous_variant | 0.52 | ethambutol | |
embA | 4245299 | c.2067A>G | synonymous_variant | 0.52 | ethambutol | |
embA | 4245315 | p.Val695Thr | missense_variant | 0.48 | ethambutol | |
embA | 4245328 | p.Ala699Val | missense_variant | 0.52 | ethambutol | |
embA | 4245335 | c.2103A>G | synonymous_variant | 0.54 | ethambutol | |
embA | 4245340 | p.Gly703Ala | missense_variant | 0.57 | ethambutol | |
embA | 4245345 | p.Met705Leu | missense_variant | 0.58 | ethambutol | |
embA | 4245348 | p.Ala706Thr | missense_variant | 0.6 | ethambutol | |
embA | 4245355 | p.Ala708Gly | missense_variant | 0.6 | ethambutol | |
embA | 4245368 | c.2136T>C | synonymous_variant | 0.64 | ethambutol | |
embA | 4245377 | c.2145T>C | synonymous_variant | 0.6 | ethambutol | |
embA | 4245388 | p.Ala719Gly | missense_variant | 0.57 | ethambutol | |
embB | 4246256 | c.-258G>T | upstream_gene_variant | 0.43 | ethambutol | |
embB | 4246259 | c.-255G>C | upstream_gene_variant | 0.43 | ethambutol | |
embA | 4246264 | p.His1011Arg | missense_variant | 0.43 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 0.43 | ethambutol | |
embB | 4247386 | c.873T>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4247389 | c.876C>G | synonymous_variant | 0.29 | ethambutol | |
embB | 4247395 | c.882C>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4247401 | c.888T>C | synonymous_variant | 0.32 | ethambutol | |
embB | 4247407 | c.894G>C | synonymous_variant | 0.32 | ethambutol | |
embB | 4247425 | c.912G>C | synonymous_variant | 0.3 | ethambutol | |
embB | 4247434 | c.921C>G | synonymous_variant | 0.29 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embB | 4247440 | c.927C>G | synonymous_variant | 0.31 | ethambutol | |
embB | 4247446 | c.933C>T | synonymous_variant | 0.35 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.41 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.43 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.45 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.38 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 0.41 | ethambutol | |
embB | 4247572 | c.1059A>G | synonymous_variant | 0.41 | ethambutol | |
embB | 4247579 | p.Ala356Phe | missense_variant | 0.38 | ethambutol | |
embB | 4247587 | c.1074G>A | synonymous_variant | 0.37 | ethambutol | |
embB | 4247603 | c.1090C>T | synonymous_variant | 0.42 | ethambutol | |
embB | 4247611 | c.1098G>T | synonymous_variant | 0.41 | ethambutol | Not assoc w R - Interim |
embB | 4247614 | c.1101T>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
embB | 4247629 | c.1116C>G | synonymous_variant | 0.35 | ethambutol | |
embB | 4247632 | c.1119C>G | synonymous_variant | 0.35 | ethambutol | |
embB | 4247638 | c.1125G>T | synonymous_variant | 0.38 | ethambutol | |
embB | 4247646 | p.Glu378Ala | missense_variant | 0.36 | ethambutol | Not assoc w R |
embB | 4247656 | c.1143A>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4247659 | c.1146C>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4247662 | c.1149C>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4247683 | c.1170C>G | synonymous_variant | 0.45 | ethambutol | |
embB | 4247692 | c.1179C>G | synonymous_variant | 0.5 | ethambutol | |
embB | 4247716 | c.1203C>T | synonymous_variant | 0.44 | ethambutol | |
embB | 4247722 | c.1209G>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4247725 | c.1212G>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4247729 | p.Gly406Pro | missense_variant | 0.46 | ethambutol | |
embB | 4247746 | c.1233C>T | synonymous_variant | 0.42 | ethambutol | |
embB | 4247761 | c.1248T>C | synonymous_variant | 0.42 | ethambutol | |
embB | 4247773 | c.1260G>A | synonymous_variant | 0.44 | ethambutol | |
embB | 4247776 | c.1263G>T | synonymous_variant | 0.42 | ethambutol | |
embB | 4247797 | c.1284C>G | synonymous_variant | 0.46 | ethambutol | |
embB | 4247800 | c.1287A>T | synonymous_variant | 0.45 | ethambutol | |
embB | 4247803 | c.1290G>C | synonymous_variant | 0.46 | ethambutol | |
embB | 4247815 | c.1302C>G | synonymous_variant | 0.46 | ethambutol | |
embB | 4247819 | p.Val436Ile | missense_variant | 0.43 | ethambutol | Uncertain significance |
embB | 4247830 | c.1317A>G | synonymous_variant | 0.48 | ethambutol | Not assoc w R - Interim |
embB | 4247836 | c.1323A>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
embB | 4247839 | c.1326G>C | synonymous_variant | 0.45 | ethambutol | Not assoc w R - Interim |
embB | 4247866 | c.1353G>C | synonymous_variant | 0.52 | ethambutol | |
embB | 4247875 | c.1362G>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 0.5 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.56 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.57 | ethambutol | Not assoc w R - Interim |
embB | 4247893 | c.1380C>T | synonymous_variant | 0.56 | ethambutol | |
embB | 4247899 | p.Met462Ile | missense_variant | 0.57 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 0.57 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.59 | ethambutol | |
embB | 4247914 | c.1401G>C | synonymous_variant | 0.58 | ethambutol | Not assoc w R - Interim |
embB | 4247932 | c.1419C>G | synonymous_variant | 0.51 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.51 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.51 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.51 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embB | 4247974 | c.1461C>G | synonymous_variant | 0.59 | ethambutol | |
embB | 4248007 | c.1494C>G | synonymous_variant | 0.59 | ethambutol | |
embB | 4248011 | p.Ser500Arg | missense_variant | 0.59 | ethambutol | |
embB | 4248014 | p.Thr501Ala | missense_variant | 0.63 | ethambutol | Uncertain significance |
embB | 4248035 | p.Val508Ile | missense_variant | 0.75 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 0.75 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.75 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.75 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.69 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.57 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.56 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.52 | ethambutol | Not assoc w R - Interim |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.47 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.42 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.4 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.39 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.4 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.52 | ethambutol | |
embB | 4248316 | c.1803C>G | synonymous_variant | 0.48 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.48 | ethambutol | |
embB | 4248343 | c.1830G>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.4 | ethambutol | |
embB | 4248355 | c.1842A>G | synonymous_variant | 0.37 | ethambutol | |
embB | 4248358 | c.1845C>G | synonymous_variant | 0.35 | ethambutol | |
embB | 4248361 | c.1848A>C | synonymous_variant | 0.35 | ethambutol | |
embB | 4248362 | p.Ser617Ala | missense_variant | 0.35 | ethambutol | |
embB | 4248373 | c.1860C>G | synonymous_variant | 0.36 | ethambutol | |
embB | 4248382 | c.1869C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4248386 | c.1873C>A | synonymous_variant | 0.39 | ethambutol | |
embB | 4248407 | p.Leu632Val | missense_variant | 0.27 | ethambutol | |
embB | 4248412 | p.Phe633Leu | missense_variant | 0.27 | ethambutol | |
embB | 4248419 | p.Leu636Met | missense_variant | 0.27 | ethambutol | |
embB | 4248425 | c.1912T>C | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embB | 4248430 | c.1917T>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4248432 | p.Trp640Phe | missense_variant | 0.29 | ethambutol | |
aftB | 4267272 | p.Lys522Arg | missense_variant | 0.94 | ethambutol | Not assoc w R |
aftB | 4267325 | c.1512G>C | synonymous_variant | 0.32 | ethambutol | |
aftB | 4267334 | c.1503T>C | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
aftB | 4267355 | p.Leu494Val | missense_variant | 0.32 | ethambutol | |
aftB | 4267364 | p.Met491Leu | missense_variant | 0.3 | ethambutol | |
ethR | 4328004 | c.456G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin |