TB-Profiler

TB-Profiler result

Run: SRR11342649

Summary

Run ID: SRR11342649

Sample name:

Date: 2024-10-04T11:36:32.529352

Number of reads: 4961002

Percentage reads mapped: 64.6

Median coverage: 87.0

Strain: lineage4.3.3

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs

Lineage	Family	RDs	Frequency
lineage4.3	Euro-American (LAM)	None	1.0
lineage4	Euro-American	None	1.0
lineage4.3.3	Euro-American (LAM)	RD115	1.0

Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin	rpoB	p.Ser441Ala	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
rifampicin	rpoB	p.Ser450Asn	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
p.Leu464Met		Mutation from literature
isoniazid	inhA	c.-770T>A	Assoc w R - Interim	Alias fabG1_c.-8T>A. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
isoniazid	katG	p.Ser315Thr	Assoc w R	High-level resistance
ethambutol	embB	p.Met306Val	Assoc w R
pyrazinamide	pncA	p.Val139Gly	Assoc w R
streptomycin	rrs	n.799C>T	Uncertain significance	Mutation from literature
streptomycin	rrs	n.888G>A	Uncertain significance	Mutation from literature
gid	c.160_290del	Assoc w R
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin	rrs	n.1402C>A	Uncertain significance	Mutation from literature
amikacin	rrs	n.1484G>T	Assoc w R
capreomycin	rrs	n.1402C>A	Uncertain significance	Mutation from literature
capreomycin	rrs	n.1484G>T	Assoc w R
kanamycin	rrs	n.1402C>A	Uncertain significance	Mutation from literature
kanamycin	rrs	n.1484G>T	Assoc w R
cycloserine
ethionamide	inhA	c.-770T>A	Assoc w R - Interim	Alias fabG1_c.-8T>A
ethionamide	ethA	c.-11A>G	Uncertain significance	Mutation from literature
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid

Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rpoB	761127	p.Ser441Ala	missense_variant	0.93	rifampicin	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
rpoB	761154	p.Ser450Asn	missense_variant	0.64	rifampicin	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
rpoB	761196	p.Leu464Met	missense_variant	0.67	rifampicin		Mutation from literature
rrs	1472644	n.799C>T	non_coding_transcript_exon_variant	0.23	streptomycin	Uncertain significance	Mutation from literature
rrs	1472733	n.888G>A	non_coding_transcript_exon_variant	0.69	streptomycin	Uncertain significance	Mutation from literature
rrs	1473247	n.1402C>A	non_coding_transcript_exon_variant	0.55	amikacin	Uncertain significance	Mutation from literature
					capreomycin	Uncertain significance	Mutation from literature
					kanamycin	Uncertain significance	Mutation from literature
rrs	1473329	n.1484G>T	non_coding_transcript_exon_variant	0.52	amikacin	Assoc w R
					capreomycin	Assoc w R
					kanamycin	Assoc w R
inhA	1673432	c.-770T>A	upstream_gene_variant	1.0	ethionamide	Assoc w R - Interim	Alias fabG1_c.-8T>A
inhA	1673432	c.-770T>A	upstream_gene_variant	1.0	isoniazid	Assoc w R - Interim	Alias fabG1_c.-8T>A. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
katG	2155168	p.Ser315Thr	missense_variant	1.0	isoniazid	Assoc w R	High-level resistance
pncA	2288826	p.Val139Gly	missense_variant	1.0	pyrazinamide	Assoc w R
embB	4247429	p.Met306Val	missense_variant	1.0	ethambutol	Assoc w R
ethA	4327484	c.-11A>G	upstream_gene_variant	1.0	ethionamide	Uncertain significance	Mutation from literature
gid	4407912	c.160_290del	frameshift_variant	1.0	streptomycin	Assoc w R

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
gyrA	7362	p.Glu21Gln	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7362	p.Glu21Gln	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	8040	p.Gly247Ser	missense_variant	0.96	levofloxacin	Not assoc w R
gyrA	8040	p.Gly247Ser	missense_variant	0.96	moxifloxacin	Not assoc w R
gyrA	9304	p.Gly668Asp	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	9304	p.Gly668Asp	missense_variant	1.0	moxifloxacin	Not assoc w R
rpoB	760991	c.1185G>C	synonymous_variant	0.34	rifampicin
rpoB	760997	c.1191G>C	synonymous_variant	0.59	rifampicin	Not assoc w R - Interim
rpoB	761015	c.1209G>C	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoB	761021	c.1215G>C	synonymous_variant	0.76	rifampicin
rpoB	761027	c.1221A>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	761031	p.Gln409Asn	missense_variant	0.8	rifampicin
rpoB	761036	c.1230G>C	synonymous_variant	0.38	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231_1233delTTGinsCTC	synonymous_variant	0.84	rifampicin
rpoB	761054	c.1248G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761058	p.Val418Thr	missense_variant	0.92	rifampicin
rpoB	761088	c.1282_1283delAGinsTC	synonymous_variant	0.93	rifampicin
rpoB	761096	c.1290G>C	synonymous_variant	0.6	rifampicin
rpoB	761102	c.1296A>G	synonymous_variant	0.95	rifampicin
rpoB	761132	c.1326G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	761133	c.1327T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>C	synonymous_variant	0.57	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>T	synonymous_variant	0.29	rifampicin	Not assoc w R - Interim
rpoB	761159	c.1353G>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	761165	c.1359G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	761168	c.1362C>G	synonymous_variant	0.17	rifampicin
rpoB	761180	c.1374A>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	761186	p.Glu460Asp	missense_variant	0.2	rifampicin	Uncertain significance
rpoB	761189	c.1383T>C	synonymous_variant	0.51	rifampicin	Not assoc w R - Interim
rpoB	761192	c.1386C>A	synonymous_variant	0.23	rifampicin
rpoB	761193	p.Gly463Ser	missense_variant	0.44	rifampicin
rpoB	761201	c.1395G>A	synonymous_variant	0.23	rifampicin
rpoB	761204	c.1398C>T	synonymous_variant	0.24	rifampicin
rpoB	761207	c.1401C>A	synonymous_variant	0.23	rifampicin
rpoB	761213	c.1407G>C	synonymous_variant	0.63	rifampicin
rpoB	761217	p.Pro471Thr	missense_variant	0.34	rifampicin
rpoB	761231	c.1425C>G	synonymous_variant	0.36	rifampicin
rpoB	761234	c.1428G>C	synonymous_variant	0.35	rifampicin	Not assoc w R - Interim
rpoB	761243	c.1437G>C	synonymous_variant	0.42	rifampicin
rpoB	761246	c.1440C>T	synonymous_variant	0.23	rifampicin	Not assoc w R - Interim
rpoB	761496	p.Tyr564His	missense_variant	0.98	rifampicin	Uncertain significance
rpoB	761507	c.1701G>C	synonymous_variant	0.19	rifampicin
rpoB	761510	c.1704T>G	synonymous_variant	0.2	rifampicin
rpoB	761511	p.Glu569Gln	missense_variant	0.29	rifampicin
rpoB	761520	p.Tyr572Leu	missense_variant	0.39	rifampicin
rpoB	761534	c.1728G>C	synonymous_variant	0.61	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoB	761557	p.Ala584Gly	missense_variant	0.63	rifampicin	Uncertain significance
rpoB	761562	p.Ala586Ser	missense_variant	0.62	rifampicin
rpoB	761565	p.Met587Leu	missense_variant	0.62	rifampicin
rpoB	761570	c.1764T>C	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	0.66	rifampicin	Not assoc w R - Interim
rpoB	761600	c.1794T>C	synonymous_variant	0.73	rifampicin
rpoB	761612	c.1806G>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoB	761633	c.1827G>C	synonymous_variant	0.7	rifampicin
rpoB	761642	c.1836G>C	synonymous_variant	0.68	rifampicin
rpoB	761643	p.Val613Ile	missense_variant	0.67	rifampicin	Uncertain significance
rpoB	761648	c.1842T>C	synonymous_variant	0.38	rifampicin
rpoB	761649	p.Ser615Pro	missense_variant	0.67	rifampicin
rpoB	761654	p.Glu616Asp	missense_variant	0.66	rifampicin
rpoB	761672	c.1866C>G	synonymous_variant	0.55	rifampicin
rpoB	761675	c.1869G>C	synonymous_variant	0.5	rifampicin
rpoB	761683	p.Leu626Arg	missense_variant	0.51	rifampicin
rpoB	761688	p.Ala628Thr	missense_variant	0.44	rifampicin
rpoB	761693	c.1887G>C	synonymous_variant	0.35	rifampicin
rpoB	761694	p.Ile630Val	missense_variant	0.4	rifampicin
rpoB	761712	p.Val636Leu	missense_variant	0.28	rifampicin
rpoB	761717	c.1911C>G	synonymous_variant	0.19	rifampicin
rpoB	761925	p.Met707Leu	missense_variant	0.19	rifampicin
rpoB	761930	c.2124G>C	synonymous_variant	0.3	rifampicin
rpoB	761937	p.Lys711Gln	missense_variant	0.46	rifampicin
rpoB	761945	c.2139G>C	synonymous_variant	0.5	rifampicin
rpoB	761951	c.2145G>C	synonymous_variant	0.52	rifampicin
rpoB	761955	p.Ile717Phe	missense_variant	0.56	rifampicin
rpoB	761961	p.Pro719Thr	missense_variant	0.6	rifampicin
rpoB	761974	p.His723Leu	missense_variant	0.68	rifampicin
rpoB	761990	c.2184G>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoB	761997	p.Leu731Ile	missense_variant	0.52	rifampicin
rpoB	762003	p.Asn733Gln	missense_variant	0.66	rifampicin
rpoB	762008	c.2202C>T	synonymous_variant	0.23	rifampicin	Not assoc w R - Interim
rpoB	762009	p.Leu735Val	missense_variant	0.65	rifampicin
rpoB	762016	p.Glu737Ala	missense_variant	0.65	rifampicin
rpoB	762024	p.Val740Met	missense_variant	0.66	rifampicin
rpoB	762053	c.2247T>C	synonymous_variant	0.66	rifampicin	Not assoc w R - Interim
rpoB	762057	p.Ile751Val	missense_variant	0.66	rifampicin	Uncertain significance
rpoB	762062	c.2256T>C	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	0.63	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	0.35	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
rpoB	762110	c.2304G>C	synonymous_variant	0.35	rifampicin
rpoB	762114	p.Ile770Val	missense_variant	0.2	rifampicin	Uncertain significance
rpoB	762143	c.2337T>C	synonymous_variant	0.22	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	0.29	rifampicin	Not assoc w R - Interim
rpoB	762156	p.Val784Ile	missense_variant	0.31	rifampicin
rpoB	762167	c.2361T>C	synonymous_variant	0.26	rifampicin	Not assoc w R - Interim
rpoB	762176	c.2370T>C	synonymous_variant	0.38	rifampicin	Not assoc w R - Interim
rpoB	762180	p.Asp792Ser	missense_variant	0.3	rifampicin
rpoB	762185	c.2379G>C	synonymous_variant	0.36	rifampicin	Not assoc w R - Interim
rpoB	762194	c.2388G>C	synonymous_variant	0.46	rifampicin	Not assoc w R - Interim
rpoB	762197	c.2391C>G	synonymous_variant	0.33	rifampicin
rpoB	762206	c.2400C>G	synonymous_variant	0.34	rifampicin
rpoB	762212	c.2406G>C	synonymous_variant	0.37	rifampicin	Not assoc w R - Interim
rpoB	762218	c.2412T>C	synonymous_variant	0.24	rifampicin
rpoB	762233	p.Pro810Ser	missense_variant	0.35	rifampicin
rpoB	762245	c.2439G>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
rpoB	762248	c.2442G>C	synonymous_variant	0.44	rifampicin
rpoB	762254	c.2448T>C	synonymous_variant	0.49	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>C	synonymous_variant	0.2	rifampicin	Not assoc w R - Interim
rpoB	762827	c.3021G>C	synonymous_variant	0.31	rifampicin	Not assoc w R - Interim
rpoB	762831	c.3025_3026delAGinsTC	synonymous_variant	0.33	rifampicin	Not assoc w R - Interim
rpoB	762836	c.3030C>T	synonymous_variant	0.3	rifampicin	Not assoc w R - Interim
rpoC	762842	c.-528G>C	upstream_gene_variant	0.44	rifampicin
rpoB	762849	p.Tyr1015Asp	missense_variant	0.19	rifampicin
rpoC	762854	c.-516G>C	upstream_gene_variant	0.34	rifampicin
rpoB	762855	p.Val1017Ile	missense_variant	0.59	rifampicin
rpoB	762858	p.Thr1018Ser	missense_variant	0.8	rifampicin
rpoC	762863	c.-507T>G	upstream_gene_variant	0.57	rifampicin
rpoB	762879	p.Met1025Leu	missense_variant	0.87	rifampicin	Uncertain significance
rpoB	762887	c.3081G>C	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoC	762896	c.-474G>C	upstream_gene_variant	0.45	rifampicin
rpoC	762902	c.-468C>T	upstream_gene_variant	0.23	rifampicin
rpoC	762911	c.-459C>T	upstream_gene_variant	0.22	rifampicin
rpoC	762917	c.-453C>T	upstream_gene_variant	0.22	rifampicin
rpoB	762920	c.3114C>T	synonymous_variant	0.24	rifampicin	Not assoc w R - Interim
rpoC	762926	c.-444C>G	upstream_gene_variant	0.44	rifampicin
rpoB	762929	c.3123G>C	synonymous_variant	0.35	rifampicin	Not assoc w R - Interim
rpoB	762929	c.3123G>T	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoC	762938	c.-432G>C	upstream_gene_variant	0.6	rifampicin
rpoC	762944	c.-426C>T	upstream_gene_variant	0.25	rifampicin
rpoC	762956	c.-414G>C	upstream_gene_variant	0.28	rifampicin
rpoB	762962	c.3156C>T	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoC	762971	c.-399G>C	upstream_gene_variant	0.47	rifampicin
rpoC	762980	c.-390T>C	upstream_gene_variant	0.19	rifampicin
rpoC	762983	c.-387C>T	upstream_gene_variant	0.64	rifampicin
rpoC	762989	c.-381G>C	upstream_gene_variant	0.76	rifampicin
rpoB	762995	c.3189G>T	synonymous_variant	0.61	rifampicin	Not assoc w R - Interim
rpoB	763005	p.Cys1067Gly	missense_variant	0.43	rifampicin	Uncertain significance
rpoB	763006	p.Cys1067Leu	missense_variant	0.48	rifampicin
rpoB	763014	p.Met1070Leu	missense_variant	0.19	rifampicin
rpoB	763017	p.Gln1071Glu	missense_variant	0.53	rifampicin
rpoC	763022	c.-348C>G	upstream_gene_variant	0.23	rifampicin
rpoB	763028	c.3222T>C	synonymous_variant	0.4	rifampicin	Not assoc w R - Interim
rpoB	763031	c.3225T>C	synonymous_variant	0.17	rifampicin	Not assoc w R
rpoB	763038	p.Thr1078Ala	missense_variant	0.39	rifampicin
rpoC	763049	c.-321G>A	upstream_gene_variant	0.21	rifampicin
rpoC	763053	c.-317_-315delTTGinsCTC	upstream_gene_variant	0.34	rifampicin
rpoB	763077	p.Val1091Thr	missense_variant	0.27	rifampicin
rpoC	763456	c.87A>G	synonymous_variant	0.3	rifampicin	Not assoc w R - Interim
rpoC	763462	c.93G>C	synonymous_variant	0.35	rifampicin
rpoC	763468	c.99G>C	synonymous_variant	0.42	rifampicin	Not assoc w R - Interim
rpoC	763483	c.114G>C	synonymous_variant	0.53	rifampicin
rpoC	763486	c.117T>C	synonymous_variant	0.54	rifampicin	Not assoc w R - Interim
rpoC	763492	c.123G>C	synonymous_variant	0.45	rifampicin	Not assoc w R - Interim
rpoC	763504	c.135C>G	synonymous_variant	0.19	rifampicin
rpoC	763507	c.138G>C	synonymous_variant	0.69	rifampicin
rpoC	763528	c.159G>C	synonymous_variant	0.69	rifampicin
rpoC	763531	c.162G>C	synonymous_variant	0.76	rifampicin	Not assoc w R
rpoC	763534	c.165T>C	synonymous_variant	0.76	rifampicin
rpoC	763537	c.168C>G	synonymous_variant	0.46	rifampicin
rpoC	763546	c.177A>G	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoC	763550	p.Tyr61Ala	missense_variant	0.74	rifampicin
rpoC	763558	c.189C>T	synonymous_variant	0.2	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	763578	p.Phe70Tyr	missense_variant	0.81	rifampicin
rpoC	763585	c.216C>G	synonymous_variant	0.35	rifampicin
rpoC	763589	p.Ile74Val	missense_variant	0.64	rifampicin
rpoC	763606	c.237C>A	synonymous_variant	0.52	rifampicin
rpoC	763609	c.240C>G	synonymous_variant	0.28	rifampicin
rpoC	763615	c.246G>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoC	763618	c.249C>T	synonymous_variant	0.58	rifampicin
rpoC	763622	p.Ala85Ser	missense_variant	0.88	rifampicin	Uncertain significance
rpoC	763633	c.264T>C	synonymous_variant	0.2	rifampicin	Not assoc w R - Interim
rpoC	763636	c.267T>C	synonymous_variant	0.55	rifampicin
rpoC	763642	c.273G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	763647	p.Gly93Ala	missense_variant	0.5	rifampicin
rpoC	763655	p.Glu96Asn	missense_variant	0.51	rifampicin
rpoC	763660	c.291T>C	synonymous_variant	0.42	rifampicin	Not assoc w R - Interim
rpoC	763666	c.297G>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
rpoC	763669	c.300C>G	synonymous_variant	0.37	rifampicin	Not assoc w R - Interim
rpoC	763696	c.327T>C	synonymous_variant	0.41	rifampicin	Not assoc w R - Interim
rpoC	763699	c.330G>T	synonymous_variant	0.6	rifampicin
rpoC	763708	c.339G>A	synonymous_variant	0.38	rifampicin	Not assoc w R - Interim
rpoC	763708	c.339G>C	synonymous_variant	0.46	rifampicin
rpoC	763714	c.345G>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	763717	c.348T>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	763718	p.Leu117Val	missense_variant	0.41	rifampicin
rpoC	763723	c.354G>C	synonymous_variant	0.42	rifampicin
rpoC	763724	p.Asp119Asn	missense_variant	0.41	rifampicin
rpoC	763729	c.360G>C	synonymous_variant	0.38	rifampicin
rpoC	763732	c.363C>G	synonymous_variant	0.39	rifampicin
rpoC	763732	c.363C>T	synonymous_variant	0.39	rifampicin
rpoC	763735	c.366G>C	synonymous_variant	0.41	rifampicin
rpoC	763747	c.378G>A	synonymous_variant	0.37	rifampicin
rpoC	763751	p.Ile128Val	missense_variant	0.79	rifampicin
rpoC	763765	c.396T>G	synonymous_variant	0.23	rifampicin	Not assoc w R - Interim
rpoC	763772	p.Val135Met	missense_variant	0.59	rifampicin
rpoC	763775	p.Ile136Val	missense_variant	0.15	rifampicin
rpoC	763781	p.Ser138Glu	missense_variant	0.21	rifampicin
rpoC	764461	c.1092A>G	synonymous_variant	0.31	rifampicin	Not assoc w R - Interim
rpoC	764485	c.1116G>C	synonymous_variant	0.61	rifampicin
rpoC	764491	c.1122G>T	synonymous_variant	0.61	rifampicin
rpoC	764497	p.Glu376Asp	missense_variant	0.54	rifampicin
rpoC	764498	p.Ser377Ala	missense_variant	0.55	rifampicin
rpoC	764503	c.1134G>C	synonymous_variant	0.62	rifampicin
rpoC	764509	c.1140G>C	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoC	764521	c.1152T>C	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>C	synonymous_variant	0.63	rifampicin
rpoC	764539	c.1170C>G	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoC	764548	c.1179G>C	synonymous_variant	0.67	rifampicin
rpoC	764549	p.Pro394Val	missense_variant	0.77	rifampicin
rpoC	764560	c.1191T>C	synonymous_variant	0.29	rifampicin	Not assoc w R - Interim
rpoC	764566	c.1197C>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	764572	c.1203G>C	synonymous_variant	0.89	rifampicin
rpoC	764575	c.1206T>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	764581	c.1212T>C	synonymous_variant	0.94	rifampicin
rpoC	764582	p.Leu405Met	missense_variant	0.93	rifampicin
rpoC	764602	c.1233C>T	synonymous_variant	0.2	rifampicin
rpoC	764605	c.1236G>C	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoC	764605	c.1236G>T	synonymous_variant	0.24	rifampicin
rpoC	764611	c.1242G>C	synonymous_variant	0.59	rifampicin
rpoC	764611	c.1242G>T	synonymous_variant	0.34	rifampicin	Not assoc w R - Interim
rpoC	764620	c.1251G>C	synonymous_variant	0.28	rifampicin
rpoC	764623	c.1254C>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	764626	c.1257C>T	synonymous_variant	0.32	rifampicin	Not assoc w R - Interim
rpoC	764632	c.1263T>C	synonymous_variant	0.59	rifampicin	Not assoc w R - Interim
rpoC	764635	c.1266C>G	synonymous_variant	0.55	rifampicin
rpoC	764635	c.1266C>T	synonymous_variant	0.31	rifampicin
rpoC	764644	c.1275G>C	synonymous_variant	0.38	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>T	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoC	764651	c.1282_1284delTCGinsAGC	synonymous_variant	0.35	rifampicin
rpoC	764656	c.1287C>G	synonymous_variant	0.37	rifampicin
rpoC	764659	c.1290C>T	synonymous_variant	0.35	rifampicin
rpoC	764662	c.1293G>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
rpoC	764665	c.1296C>T	synonymous_variant	0.41	rifampicin
rpoC	764668	c.1299C>T	synonymous_variant	0.34	rifampicin	Not assoc w R - Interim
rpoC	764671	c.1302G>C	synonymous_variant	0.47	rifampicin
rpoC	764671	c.1302G>T	synonymous_variant	0.35	rifampicin
rpoC	764677	c.1308C>G	synonymous_variant	0.35	rifampicin	Not assoc w R - Interim
rpoC	764678	p.Lys437Gln	missense_variant	0.35	rifampicin
rpoC	764681	p.Leu438Ile	missense_variant	0.37	rifampicin
rpoC	764692	c.1323C>T	synonymous_variant	0.43	rifampicin	Not assoc w R - Interim
rpoC	764703	p.Lys445Ser	missense_variant	0.34	rifampicin
rpoC	764706	p.Leu446Gln	missense_variant	0.84	rifampicin	Uncertain significance
rpoC	764713	c.1344G>C	synonymous_variant	0.38	rifampicin	Not assoc w R - Interim
rpoC	764731	c.1362G>C	synonymous_variant	0.81	rifampicin
rpoC	764737	c.1368G>C	synonymous_variant	0.29	rifampicin
rpoC	764737	c.1368G>T	synonymous_variant	0.5	rifampicin
rpoC	764746	c.1377G>T	synonymous_variant	0.48	rifampicin	Not assoc w R - Interim
rpoC	764755	p.Asp462Glu	missense_variant	0.56	rifampicin
rpoC	764758	c.1389C>G	synonymous_variant	0.33	rifampicin	Not assoc w R - Interim
rpoC	764760	p.Asn464Ser	missense_variant	0.35	rifampicin
rpoC	764764	c.1395T>C	synonymous_variant	0.43	rifampicin	Not assoc w R - Interim
rpoC	764767	c.1398G>T	synonymous_variant	0.41	rifampicin
rpoC	764776	c.1407C>T	synonymous_variant	0.31	rifampicin
rpoC	764781	p.Ser471Thr	missense_variant	0.17	rifampicin
rpoC	764785	c.1416C>T	synonymous_variant	0.23	rifampicin
rpoC	764797	c.1428G>C	synonymous_variant	0.15	rifampicin
rpoC	764995	c.1626C>G	synonymous_variant	1.0	rifampicin	Not assoc w R
rpoC	765903	p.Thr845Ser	missense_variant	0.35	rifampicin
rpoC	765907	c.2538G>C	synonymous_variant	0.41	rifampicin
rpoC	765923	p.Asn852Ala	missense_variant	0.46	rifampicin
rpoC	765937	c.2568T>C	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoC	765940	c.2571A>T	synonymous_variant	0.45	rifampicin	Not assoc w R - Interim
rpoC	765947	c.2578T>C	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoC	765958	c.2589C>G	synonymous_variant	0.47	rifampicin
rpoC	765962	c.2593T>C	synonymous_variant	0.49	rifampicin
rpoC	765967	c.2598C>T	synonymous_variant	0.46	rifampicin	Not assoc w R - Interim
rpoC	765988	c.2619G>C	synonymous_variant	0.5	rifampicin
rpoC	765991	c.2622C>G	synonymous_variant	0.47	rifampicin
rpoC	765994	c.2625A>T	synonymous_variant	0.42	rifampicin	Not assoc w R - Interim
rpoC	766003	c.2634G>C	synonymous_variant	0.5	rifampicin
rpoC	766009	c.2640G>C	synonymous_variant	0.52	rifampicin	Not assoc w R - Interim
rpoC	766021	c.2652G>C	synonymous_variant	0.41	rifampicin
rpoC	766027	c.2658G>C	synonymous_variant	0.35	rifampicin
rpoC	766034	p.His889Glu	missense_variant	0.26	rifampicin
mmpL5	775639	p.Ile948Val	missense_variant	1.0	bedaquiline	Not assoc w R - Interim
mmpL5	775639	p.Ile948Val	missense_variant	1.0	clofazimine	Not assoc w R
rpsL	781395	c.-165T>C	upstream_gene_variant	1.0	streptomycin	Not assoc w R
rpsL	781760	c.201T>C	synonymous_variant	0.19	streptomycin
rpsL	781802	c.243G>C	synonymous_variant	0.18	streptomycin
rplC	800612	c.-197A>G	upstream_gene_variant	0.19	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	0.23	linezolid
rplC	800632	c.-177_-176delATinsTC	upstream_gene_variant	0.25	linezolid
rplC	800639	c.-170C>G	upstream_gene_variant	0.19	linezolid
rplC	800645	c.-164C>G	upstream_gene_variant	0.24	linezolid
rplC	800648	c.-161A>G	upstream_gene_variant	0.24	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.23	linezolid
rplC	800667	c.-142_-140delTCGinsAGC	upstream_gene_variant	0.21	linezolid
rplC	800672	c.-137G>C	upstream_gene_variant	0.21	linezolid
rplC	800693	c.-116A>G	upstream_gene_variant	0.21	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.18	linezolid
rplC	800715	c.-94A>G	upstream_gene_variant	0.17	linezolid
rrs	1471659	n.-187C>T	upstream_gene_variant	1.0	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472068	n.223T>G	non_coding_transcript_exon_variant	0.57	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	0.74	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472078	n.233C>T	non_coding_transcript_exon_variant	0.73	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472080	n.235G>A	non_coding_transcript_exon_variant	0.16	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472102	n.257G>A	non_coding_transcript_exon_variant	0.41	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472106	n.261G>A	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	0.44	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472112	n.267C>T	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472113	n.268T>C	non_coding_transcript_exon_variant	0.48	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472123	n.278A>G	non_coding_transcript_exon_variant	0.26	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472124	n.279C>T	non_coding_transcript_exon_variant	0.44	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472150	n.305T>A	non_coding_transcript_exon_variant	0.67	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472150	n.305T>G	non_coding_transcript_exon_variant	0.32	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472151	n.306C>A	non_coding_transcript_exon_variant	0.38	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472155	n.310C>T	non_coding_transcript_exon_variant	0.36	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472172	n.327T>C	non_coding_transcript_exon_variant	0.82	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472225	n.380C>A	non_coding_transcript_exon_variant	0.19	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472239	n.394C>T	non_coding_transcript_exon_variant	0.24	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472251	n.406G>A	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472258	n.413A>G	non_coding_transcript_exon_variant	0.26	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472259	n.414C>A	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472282	n.437T>G	non_coding_transcript_exon_variant	0.28	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472285	n.440A>G	non_coding_transcript_exon_variant	0.68	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472289	n.444T>G	non_coding_transcript_exon_variant	0.7	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472290	n.445C>T	non_coding_transcript_exon_variant	0.66	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472293	n.448C>A	non_coding_transcript_exon_variant	0.48	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472295	n.450_466delAAGGTCCGGGTTCTCTCinsCAGGCCTGCTCCTTGTGGGT	non_coding_transcript_exon_variant	0.54	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472314	n.469A>G	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472325	n.480G>C	non_coding_transcript_exon_variant	0.8	kanamycin
					capreomycin
					streptomycin	Uncertain significance
					amikacin
rrs	1472330	n.485G>T	non_coding_transcript_exon_variant	0.6	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472338	n.493A>G	non_coding_transcript_exon_variant	0.77	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472344	n.499C>T	non_coding_transcript_exon_variant	0.87	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472379	n.534T>C	non_coding_transcript_exon_variant	0.79	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472400	n.555C>T	non_coding_transcript_exon_variant	0.85	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472412	n.567A>G	non_coding_transcript_exon_variant	0.22	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472416	n.571C>T	non_coding_transcript_exon_variant	0.58	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472422	n.577T>C	non_coding_transcript_exon_variant	0.72	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472427	n.582T>G	non_coding_transcript_exon_variant	0.17	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472435	n.590T>C	non_coding_transcript_exon_variant	0.39	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472436	n.591G>T	non_coding_transcript_exon_variant	0.36	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472437	n.592T>G	non_coding_transcript_exon_variant	0.35	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472438	n.593T>C	non_coding_transcript_exon_variant	0.28	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472448	n.603T>C	non_coding_transcript_exon_variant	0.31	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472449	n.604C>T	non_coding_transcript_exon_variant	0.31	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472450	n.605A>C	non_coding_transcript_exon_variant	0.32	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472451	n.606C>T	non_coding_transcript_exon_variant	0.32	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472462	n.617T>G	non_coding_transcript_exon_variant	0.33	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472464	n.619A>G	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472473	n.628G>T	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472474	n.629C>G	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472476	n.631A>G	non_coding_transcript_exon_variant	0.61	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472494	n.649A>G	non_coding_transcript_exon_variant	0.91	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472496	n.651T>A	non_coding_transcript_exon_variant	0.9	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472498	n.653C>T	non_coding_transcript_exon_variant	0.93	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472507	n.662C>G	non_coding_transcript_exon_variant	0.44	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472517	n.672T>A	non_coding_transcript_exon_variant	0.4	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472518	n.673G>T	non_coding_transcript_exon_variant	0.42	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472530	n.685G>A	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472537	n.692C>T	non_coding_transcript_exon_variant	0.5	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472544	n.699C>A	non_coding_transcript_exon_variant	0.47	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472545	n.700A>T	non_coding_transcript_exon_variant	0.45	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472558	n.713G>A	non_coding_transcript_exon_variant	0.34	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472566	n.721G>A	non_coding_transcript_exon_variant	0.44	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472569	n.724G>A	non_coding_transcript_exon_variant	0.34	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472571	n.726G>C	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472579	n.734G>T	non_coding_transcript_exon_variant	0.37	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472581	n.736A>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472597	n.752G>A	non_coding_transcript_exon_variant	0.3	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472598	n.753A>C	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472599	n.754G>T	non_coding_transcript_exon_variant	0.49	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472607	n.762G>A	non_coding_transcript_exon_variant	0.28	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472616	n.771G>A	non_coding_transcript_exon_variant	0.55	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472655	n.810G>A	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472655	n.810G>T	non_coding_transcript_exon_variant	0.36	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472658	n.813G>A	non_coding_transcript_exon_variant	0.62	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472660	n.815T>C	non_coding_transcript_exon_variant	0.36	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472661	n.816A>G	non_coding_transcript_exon_variant	0.62	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472670	n.825_828delGGGTinsTGGG	non_coding_transcript_exon_variant	0.74	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472670	n.828_829delTTinsGG	non_coding_transcript_exon_variant	0.26	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472675	n.830_832delTCCinsACA	non_coding_transcript_exon_variant	0.25	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472675	n.830_832delTCCinsCCT	non_coding_transcript_exon_variant	0.75	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472682	n.837_842delTTGGGAinsGGGAC	non_coding_transcript_exon_variant	0.72	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472682	n.837_842delTTGGGAinsACGTTT	non_coding_transcript_exon_variant	0.27	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472690	n.845C>A	non_coding_transcript_exon_variant	0.71	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472692	n.847T>C	non_coding_transcript_exon_variant	0.29	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472697	n.852T>C	non_coding_transcript_exon_variant	0.67	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472713	n.868T>C	non_coding_transcript_exon_variant	0.66	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472714	n.869A>G	non_coding_transcript_exon_variant	0.3	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472716	n.871C>T	non_coding_transcript_exon_variant	0.66	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472742	n.897C>T	non_coding_transcript_exon_variant	0.71	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472744	n.899A>G	non_coding_transcript_exon_variant	0.72	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472781	n.936C>T	non_coding_transcript_exon_variant	0.73	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472790	n.945T>C	non_coding_transcript_exon_variant	0.24	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472793	n.948A>T	non_coding_transcript_exon_variant	0.75	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472803	n.958T>A	non_coding_transcript_exon_variant	0.67	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472824	n.979T>A	non_coding_transcript_exon_variant	0.9	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472825	n.980G>A	non_coding_transcript_exon_variant	0.22	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472827	n.982G>T	non_coding_transcript_exon_variant	0.4	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472828	n.983T>C	non_coding_transcript_exon_variant	0.86	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472840	n.995A>G	non_coding_transcript_exon_variant	0.3	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472844	n.999C>A	non_coding_transcript_exon_variant	0.28	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472848	n.1003T>C	non_coding_transcript_exon_variant	0.26	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472849	n.1004C>T	non_coding_transcript_exon_variant	0.27	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472850	n.1005T>C	non_coding_transcript_exon_variant	0.27	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472857	n.1012A>G	non_coding_transcript_exon_variant	0.28	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472863	n.1018T>G	non_coding_transcript_exon_variant	0.24	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472866	n.1021C>T	non_coding_transcript_exon_variant	0.24	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472869	n.1024G>T	non_coding_transcript_exon_variant	0.24	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472870	n.1025T>C	non_coding_transcript_exon_variant	0.24	kanamycin
					capreomycin
					streptomycin	Uncertain significance
					amikacin
rrs	1472875	n.1030T>G	non_coding_transcript_exon_variant	0.25	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472880	n.1035G>A	non_coding_transcript_exon_variant	0.65	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472892	n.1047T>C	non_coding_transcript_exon_variant	0.24	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472895	n.1050C>T	non_coding_transcript_exon_variant	0.9	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472951	n.1106T>C	non_coding_transcript_exon_variant	0.27	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472952	n.1107T>C	non_coding_transcript_exon_variant	0.33	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472953	n.1108G>A	non_coding_transcript_exon_variant	0.3	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472955	n.1110C>T	non_coding_transcript_exon_variant	0.34	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472956	n.1111T>C	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472957	n.1112C>T	non_coding_transcript_exon_variant	0.65	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472958	n.1113A>G	non_coding_transcript_exon_variant	0.32	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472973	n.1128A>T	non_coding_transcript_exon_variant	0.91	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472974	n.1129A>G	non_coding_transcript_exon_variant	0.4	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472975	n.1130T>G	non_coding_transcript_exon_variant	0.19	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472982	n.1137G>A	non_coding_transcript_exon_variant	0.2	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1472987	n.1142G>A	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472988	n.1143T>C	non_coding_transcript_exon_variant	0.35	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1472989	n.1144G>A	non_coding_transcript_exon_variant	0.34	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472990	n.1145A>G	non_coding_transcript_exon_variant	0.73	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473001	n.1156G>C	non_coding_transcript_exon_variant	0.22	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473002	n.1157G>A	non_coding_transcript_exon_variant	0.21	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473004	n.1159T>A	non_coding_transcript_exon_variant	0.23	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473008	n.1163C>T	non_coding_transcript_exon_variant	0.21	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473009	n.1164T>G	non_coding_transcript_exon_variant	0.22	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473020	n.1175T>C	non_coding_transcript_exon_variant	0.2	kanamycin
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473035	n.1190G>A	non_coding_transcript_exon_variant	0.96	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473055	n.1210C>T	non_coding_transcript_exon_variant	0.88	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473056	n.1211A>T	non_coding_transcript_exon_variant	0.99	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473066	n.1221A>G	non_coding_transcript_exon_variant	0.92	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473088	n.1243A>G	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473093	n.1248C>T	non_coding_transcript_exon_variant	0.61	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473100	n.1255G>A	non_coding_transcript_exon_variant	0.97	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473102	n.1257C>T	non_coding_transcript_exon_variant	0.57	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	1.0	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473115	n.1270G>T	non_coding_transcript_exon_variant	0.49	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473121	n.1276T>C	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473123	n.1278A>T	non_coding_transcript_exon_variant	0.52	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	0.63	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473148	n.1303G>T	non_coding_transcript_exon_variant	0.41	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473163	n.1318C>A	non_coding_transcript_exon_variant	0.4	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	0.64	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473173	n.1328C>T	non_coding_transcript_exon_variant	0.48	kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					streptomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1473221	n.1376C>T	non_coding_transcript_exon_variant	0.43	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473252	n.1407T>C	non_coding_transcript_exon_variant	0.7	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473259	n.1414C>T	non_coding_transcript_exon_variant	0.72	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1473262	n.1417T>C	non_coding_transcript_exon_variant	0.32	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473270	n.1425G>A	non_coding_transcript_exon_variant	0.61	kanamycin	Uncertain significance
					capreomycin
					streptomycin
					amikacin	Uncertain significance
rrs	1473276	n.1431A>C	non_coding_transcript_exon_variant	0.4	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473276	n.1431A>G	non_coding_transcript_exon_variant	0.59	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473283	n.1438T>C	non_coding_transcript_exon_variant	0.2	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin
					amikacin	Uncertain significance
rrs	1473284	n.1439A>T	non_coding_transcript_exon_variant	0.23	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473290	n.1445delCinsTTT	non_coding_transcript_exon_variant	0.59	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473290	n.1445delCinsTCG	non_coding_transcript_exon_variant	0.39	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473301	n.1456T>C	non_coding_transcript_exon_variant	0.6	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473301	n.1456T>G	non_coding_transcript_exon_variant	0.39	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473305	n.1460G>T	non_coding_transcript_exon_variant	0.61	kanamycin
					capreomycin
					streptomycin
					amikacin
rrs	1473314	n.1469A>G	non_coding_transcript_exon_variant	0.31	kanamycin
					capreomycin
					streptomycin	Uncertain significance
					amikacin
rrs	1473315	n.1470T>C	non_coding_transcript_exon_variant	0.31	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473316	n.1471C>T	non_coding_transcript_exon_variant	0.98	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473319	n.1474C>T	non_coding_transcript_exon_variant	0.28	kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					streptomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1473697	n.40C>T	non_coding_transcript_exon_variant	0.27	capreomycin	Uncertain significance
rrl	1473697	n.40C>T	non_coding_transcript_exon_variant	0.27	linezolid
rrl	1473698	n.41G>A	non_coding_transcript_exon_variant	0.27	capreomycin
rrl	1473698	n.41G>A	non_coding_transcript_exon_variant	0.27	linezolid
rrl	1473718	n.61G>T	non_coding_transcript_exon_variant	0.31	capreomycin
rrl	1473718	n.61G>T	non_coding_transcript_exon_variant	0.31	linezolid
rrl	1473721	n.64G>A	non_coding_transcript_exon_variant	0.31	capreomycin
rrl	1473721	n.64G>A	non_coding_transcript_exon_variant	0.31	linezolid
rrl	1473722	n.65G>T	non_coding_transcript_exon_variant	0.31	capreomycin
rrl	1473722	n.65G>T	non_coding_transcript_exon_variant	0.31	linezolid
rrl	1473731	n.74T>A	non_coding_transcript_exon_variant	0.33	capreomycin	Uncertain significance
rrl	1473731	n.74T>A	non_coding_transcript_exon_variant	0.33	linezolid	Uncertain significance
rrl	1473744	n.87T>C	non_coding_transcript_exon_variant	0.26	capreomycin
rrl	1473744	n.87T>C	non_coding_transcript_exon_variant	0.26	linezolid
rrl	1473746	n.89T>A	non_coding_transcript_exon_variant	0.25	capreomycin
rrl	1473746	n.89T>A	non_coding_transcript_exon_variant	0.25	linezolid
rrl	1473747	n.90C>T	non_coding_transcript_exon_variant	0.26	capreomycin
rrl	1473747	n.90C>T	non_coding_transcript_exon_variant	0.26	linezolid
rrl	1473751	n.94C>T	non_coding_transcript_exon_variant	0.26	capreomycin
rrl	1473751	n.94C>T	non_coding_transcript_exon_variant	0.26	linezolid
rrl	1473753	n.96A>G	non_coding_transcript_exon_variant	0.27	capreomycin
rrl	1473753	n.96A>G	non_coding_transcript_exon_variant	0.27	linezolid
rrl	1473756	n.99G>T	non_coding_transcript_exon_variant	0.26	capreomycin	Uncertain significance
rrl	1473756	n.99G>T	non_coding_transcript_exon_variant	0.26	linezolid	Uncertain significance
rrl	1473757	n.100T>G	non_coding_transcript_exon_variant	0.26	capreomycin	Uncertain significance
rrl	1473757	n.100T>G	non_coding_transcript_exon_variant	0.26	linezolid	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.27	capreomycin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.27	linezolid
rrl	1473836	n.179A>G	non_coding_transcript_exon_variant	0.24	capreomycin
rrl	1473836	n.179A>G	non_coding_transcript_exon_variant	0.24	linezolid	Uncertain significance
rrl	1473840	n.183A>G	non_coding_transcript_exon_variant	0.21	capreomycin
rrl	1473840	n.183A>G	non_coding_transcript_exon_variant	0.21	linezolid
rrl	1474112	n.455T>A	non_coding_transcript_exon_variant	0.19	capreomycin
rrl	1474112	n.455T>A	non_coding_transcript_exon_variant	0.19	linezolid
rrl	1474124	n.467G>C	non_coding_transcript_exon_variant	0.67	capreomycin
rrl	1474124	n.467G>C	non_coding_transcript_exon_variant	0.67	linezolid
rrl	1474125	n.468C>G	non_coding_transcript_exon_variant	0.68	capreomycin
rrl	1474125	n.468C>G	non_coding_transcript_exon_variant	0.68	linezolid
rrl	1474130	n.473C>T	non_coding_transcript_exon_variant	0.76	capreomycin	Uncertain significance
rrl	1474130	n.473C>T	non_coding_transcript_exon_variant	0.76	linezolid
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.79	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.79	linezolid	Uncertain significance
rrl	1474141	n.484G>C	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1474141	n.484G>C	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1474142	n.485C>G	non_coding_transcript_exon_variant	0.81	capreomycin
rrl	1474142	n.485C>G	non_coding_transcript_exon_variant	0.81	linezolid
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1474155	n.498G>A	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1474155	n.498G>A	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1474164	n.507C>T	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1474164	n.507C>T	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1474171	n.514C>T	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1474171	n.514C>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1474184	n.527C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474184	n.527C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	0.81	capreomycin	Uncertain significance
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	0.81	linezolid	Uncertain significance
rrl	1474197	n.540C>T	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1474197	n.540C>T	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1474199	n.542G>A	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1474199	n.542G>A	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1474202	n.545T>C	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1474202	n.545T>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1474269	n.612C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474269	n.612C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1474275	n.618T>G	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1474275	n.618T>G	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1474280	n.623C>T	non_coding_transcript_exon_variant	0.65	capreomycin
rrl	1474280	n.623C>T	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1474281	n.624A>G	non_coding_transcript_exon_variant	0.65	capreomycin
rrl	1474281	n.624A>G	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1474288	n.631_651delCCTTTTCCTCTCCGGAGGAGGinsTTT	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1474288	n.631_651delCCTTTTCCTCTCCGGAGGAGGinsTTT	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1474316	n.659T>C	non_coding_transcript_exon_variant	0.57	capreomycin
rrl	1474316	n.659T>C	non_coding_transcript_exon_variant	0.57	linezolid
rrl	1474317	n.660G>A	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1474317	n.660G>A	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1474348	n.691C>T	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1474348	n.691C>T	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1474351	n.694G>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1474351	n.694G>T	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1474353	n.696A>G	non_coding_transcript_exon_variant	0.57	capreomycin	Uncertain significance
rrl	1474353	n.696A>G	non_coding_transcript_exon_variant	0.57	linezolid	Uncertain significance
rrl	1474353	n.696A>T	non_coding_transcript_exon_variant	0.39	capreomycin
rrl	1474353	n.696A>T	non_coding_transcript_exon_variant	0.39	linezolid
rrl	1474354	n.697C>T	non_coding_transcript_exon_variant	0.39	capreomycin
rrl	1474354	n.697C>T	non_coding_transcript_exon_variant	0.39	linezolid
rrl	1474355	n.698A>G	non_coding_transcript_exon_variant	0.55	capreomycin	Uncertain significance
rrl	1474355	n.698A>G	non_coding_transcript_exon_variant	0.55	linezolid	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1474383	n.726G>T	non_coding_transcript_exon_variant	0.28	capreomycin
rrl	1474383	n.726G>T	non_coding_transcript_exon_variant	0.28	linezolid
rrl	1474387	n.730C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1474387	n.730C>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1474393	n.736A>G	non_coding_transcript_exon_variant	0.78	capreomycin
rrl	1474393	n.736A>G	non_coding_transcript_exon_variant	0.78	linezolid
rrl	1474402	n.745T>C	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1474402	n.745T>C	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1474406	n.749T>C	non_coding_transcript_exon_variant	0.22	capreomycin
rrl	1474406	n.749T>C	non_coding_transcript_exon_variant	0.22	linezolid
rrl	1474413	n.756_778delACCCACACGCGCATACGCGCGTGinsTT	non_coding_transcript_exon_variant	0.33	capreomycin
rrl	1474413	n.756_778delACCCACACGCGCATACGCGCGTGinsTT	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1474413	n.757_776delCCCACACGCGCATACGCGCG	non_coding_transcript_exon_variant	0.62	capreomycin
rrl	1474413	n.757_776delCCCACACGCGCATACGCGCG	non_coding_transcript_exon_variant	0.62	linezolid
rrl	1474437	n.781_782delAA	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1474437	n.781_782delAA	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1474448	n.791T>C	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1474448	n.791T>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1474467	n.810A>G	non_coding_transcript_exon_variant	0.72	capreomycin
rrl	1474467	n.810A>G	non_coding_transcript_exon_variant	0.72	linezolid
rrl	1474476	n.819C>T	non_coding_transcript_exon_variant	0.32	capreomycin
rrl	1474476	n.819C>T	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1474488	n.831G>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474488	n.831G>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474495	n.838G>A	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1474495	n.838G>A	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1474496	n.839C>A	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1474496	n.839C>A	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1474497	n.840G>C	non_coding_transcript_exon_variant	0.41	capreomycin	Uncertain significance
rrl	1474497	n.840G>C	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1474498	n.841G>T	non_coding_transcript_exon_variant	0.5	capreomycin
rrl	1474498	n.841G>T	non_coding_transcript_exon_variant	0.5	linezolid
rrl	1474505	n.848C>G	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1474505	n.848C>G	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1474506	n.849C>G	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1474506	n.849C>G	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1474507	n.850G>T	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1474507	n.850G>T	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1474508	n.851C>T	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1474508	n.851C>T	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1474516	n.859C>A	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474516	n.859C>A	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474527	n.870T>C	non_coding_transcript_exon_variant	0.43	capreomycin
rrl	1474527	n.870T>C	non_coding_transcript_exon_variant	0.43	linezolid
rrl	1474529	n.872A>C	non_coding_transcript_exon_variant	0.61	capreomycin
rrl	1474529	n.872A>C	non_coding_transcript_exon_variant	0.61	linezolid
rrl	1474530	n.873G>A	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1474530	n.873G>A	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1474537	n.880G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474537	n.880G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474539	n.882C>T	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1474539	n.882C>T	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1474540	n.883T>G	non_coding_transcript_exon_variant	0.6	capreomycin
rrl	1474540	n.883T>G	non_coding_transcript_exon_variant	0.6	linezolid
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	0.43	capreomycin
rrl	1474542	n.885A>G	non_coding_transcript_exon_variant	0.43	linezolid
rrl	1474558	n.901G>A	non_coding_transcript_exon_variant	0.47	capreomycin	Uncertain significance
rrl	1474558	n.901G>A	non_coding_transcript_exon_variant	0.47	linezolid
rrl	1474584	n.927C>T	non_coding_transcript_exon_variant	0.49	capreomycin
rrl	1474584	n.927C>T	non_coding_transcript_exon_variant	0.49	linezolid
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.31	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.31	linezolid	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.43	capreomycin	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1474634	n.977T>G	non_coding_transcript_exon_variant	0.32	capreomycin
rrl	1474634	n.977T>G	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1474636	n.979_981delACCinsCCG	non_coding_transcript_exon_variant	0.43	capreomycin
rrl	1474636	n.979_981delACCinsCCG	non_coding_transcript_exon_variant	0.43	linezolid
rrl	1474636	n.979_982delACCGinsTTGC	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1474636	n.979_982delACCGinsTTGC	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1474658	n.1001A>G	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1474658	n.1001A>G	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1474663	n.1006C>T	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1474663	n.1006C>T	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1474672	n.1015C>T	non_coding_transcript_exon_variant	0.5	capreomycin	Uncertain significance
rrl	1474672	n.1015C>T	non_coding_transcript_exon_variant	0.5	linezolid	Uncertain significance
rrl	1474673	n.1017_1018delACinsCA	non_coding_transcript_exon_variant	0.37	capreomycin
rrl	1474673	n.1017_1018delACinsCA	non_coding_transcript_exon_variant	0.37	linezolid
rrl	1474673	n.1016T>C	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1474673	n.1016T>C	non_coding_transcript_exon_variant	0.4	linezolid	Uncertain significance
rrl	1474676	n.1019T>A	non_coding_transcript_exon_variant	0.52	capreomycin	Uncertain significance
rrl	1474676	n.1019T>A	non_coding_transcript_exon_variant	0.52	linezolid	Uncertain significance
rrl	1474676	n.1019T>C	non_coding_transcript_exon_variant	0.32	capreomycin	Uncertain significance
rrl	1474676	n.1019T>C	non_coding_transcript_exon_variant	0.32	linezolid	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474692	n.1035G>A	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1474692	n.1035G>A	non_coding_transcript_exon_variant	0.51	linezolid	Uncertain significance
rrl	1474694	n.1037C>T	non_coding_transcript_exon_variant	0.33	capreomycin
rrl	1474694	n.1037C>T	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1474711	n.1054_1060delGGTGTAAinsCCGGGTAT	non_coding_transcript_exon_variant	0.4	capreomycin
rrl	1474711	n.1054_1060delGGTGTAAinsCCGGGTAT	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1474711	n.1054_1060delGGTGTAAinsCGGGTTGT	non_coding_transcript_exon_variant	0.58	capreomycin
rrl	1474711	n.1054_1060delGGTGTAAinsCGGGTTGT	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1474723	n.1066G>A	non_coding_transcript_exon_variant	0.2	capreomycin
rrl	1474723	n.1066G>A	non_coding_transcript_exon_variant	0.2	linezolid
rrl	1474734	n.1077G>A	non_coding_transcript_exon_variant	0.56	capreomycin
rrl	1474734	n.1077G>A	non_coding_transcript_exon_variant	0.56	linezolid
rrl	1474734	n.1077G>C	non_coding_transcript_exon_variant	0.42	capreomycin
rrl	1474734	n.1077G>C	non_coding_transcript_exon_variant	0.42	linezolid
rrl	1474736	n.1079C>T	non_coding_transcript_exon_variant	0.23	capreomycin
rrl	1474736	n.1079C>T	non_coding_transcript_exon_variant	0.23	linezolid
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.33	capreomycin	Uncertain significance
rrl	1474749	n.1092C>T	non_coding_transcript_exon_variant	0.33	linezolid	Uncertain significance
rrl	1474753	n.1096_1097delACinsG	non_coding_transcript_exon_variant	0.57	capreomycin
rrl	1474753	n.1096_1097delACinsG	non_coding_transcript_exon_variant	0.57	linezolid
rrl	1474753	n.1096_1097delACinsT	non_coding_transcript_exon_variant	0.43	capreomycin	Uncertain significance
rrl	1474753	n.1096_1097delACinsT	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474777	n.1120T>C	non_coding_transcript_exon_variant	0.24	capreomycin	Not assoc w R
rrl	1474777	n.1120T>C	non_coding_transcript_exon_variant	0.24	linezolid	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	0.32	capreomycin	Uncertain significance
rrl	1474779	n.1122G>A	non_coding_transcript_exon_variant	0.32	linezolid	Uncertain significance
rrl	1474782	n.1125G>A	non_coding_transcript_exon_variant	0.32	capreomycin	Not assoc w R
rrl	1474782	n.1125G>A	non_coding_transcript_exon_variant	0.32	linezolid	Uncertain significance
rrl	1474783	n.1126G>A	non_coding_transcript_exon_variant	0.22	capreomycin
rrl	1474783	n.1126G>A	non_coding_transcript_exon_variant	0.22	linezolid
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.42	capreomycin	Uncertain significance
rrl	1474823	n.1166C>G	non_coding_transcript_exon_variant	0.42	linezolid	Uncertain significance
rrl	1474824	n.1167A>G	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1474824	n.1167A>G	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1474827	n.1170C>T	non_coding_transcript_exon_variant	0.34	capreomycin	Uncertain significance
rrl	1474827	n.1170C>T	non_coding_transcript_exon_variant	0.34	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.65	linezolid	Uncertain significance
rrl	1474830	n.1173A>T	non_coding_transcript_exon_variant	0.33	capreomycin	Uncertain significance
rrl	1474830	n.1173A>T	non_coding_transcript_exon_variant	0.33	linezolid	Uncertain significance
rrl	1474831	n.1174A>C	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1474831	n.1174A>C	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1474831	n.1174A>T	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1474831	n.1174A>T	non_coding_transcript_exon_variant	0.51	linezolid	Uncertain significance
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.22	capreomycin	Uncertain significance
rrl	1474832	n.1175A>T	non_coding_transcript_exon_variant	0.22	linezolid	Uncertain significance
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Not assoc w R
rrl	1474864	n.1207C>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1474883	n.1226T>C	non_coding_transcript_exon_variant	0.37	capreomycin
rrl	1474883	n.1226T>C	non_coding_transcript_exon_variant	0.37	linezolid
rrl	1474903	n.1246T>C	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1474903	n.1246T>C	non_coding_transcript_exon_variant	0.51	linezolid	Uncertain significance
rrl	1474904	n.1247G>C	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1474904	n.1247G>C	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1474913	n.1256T>C	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1474932	n.1275C>T	non_coding_transcript_exon_variant	0.43	capreomycin	Uncertain significance
rrl	1474932	n.1275C>T	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1474951	n.1294C>A	non_coding_transcript_exon_variant	0.26	capreomycin
rrl	1474951	n.1294C>A	non_coding_transcript_exon_variant	0.26	linezolid
rrl	1475008	n.1351C>T	non_coding_transcript_exon_variant	0.31	capreomycin
rrl	1475008	n.1351C>T	non_coding_transcript_exon_variant	0.31	linezolid
rrl	1475016	n.1359C>T	non_coding_transcript_exon_variant	0.7	capreomycin
rrl	1475016	n.1359C>T	non_coding_transcript_exon_variant	0.7	linezolid
rrl	1475018	n.1361G>C	non_coding_transcript_exon_variant	0.77	capreomycin
rrl	1475018	n.1361G>C	non_coding_transcript_exon_variant	0.77	linezolid
rrl	1475026	n.1369G>C	non_coding_transcript_exon_variant	0.89	capreomycin
rrl	1475026	n.1369G>C	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1475031	n.1374G>C	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475031	n.1374G>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475059	n.1403_1404insTA	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1475059	n.1403_1404insTA	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1475062	n.1405A>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1475062	n.1405A>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1475065	n.1409_1411delCAA	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475065	n.1409_1411delCAA	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475076	n.1419_1422delCCTTinsGCCCTA	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475076	n.1419_1422delCCTTinsGCCCTA	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475080	n.1425_1426delCC	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1475080	n.1425_1426delCC	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1475090	n.1433A>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1475090	n.1433A>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1475104	n.1447T>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475104	n.1447T>A	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475114	n.1457C>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475114	n.1457C>T	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475124	n.1467A>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1475124	n.1467A>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1475171	n.1514C>T	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1475171	n.1514C>T	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1475172	n.1515A>G	non_coding_transcript_exon_variant	0.56	capreomycin
rrl	1475172	n.1515A>G	non_coding_transcript_exon_variant	0.56	linezolid
rrl	1475175	n.1518G>C	non_coding_transcript_exon_variant	0.2	capreomycin	Uncertain significance
rrl	1475175	n.1518G>C	non_coding_transcript_exon_variant	0.2	linezolid	Uncertain significance
rrl	1475188	n.1531C>G	non_coding_transcript_exon_variant	0.17	capreomycin	Uncertain significance
rrl	1475188	n.1531C>G	non_coding_transcript_exon_variant	0.17	linezolid	Uncertain significance
rrl	1475194	n.1537C>G	non_coding_transcript_exon_variant	0.33	capreomycin
rrl	1475194	n.1537C>G	non_coding_transcript_exon_variant	0.33	linezolid
rrl	1475488	n.1831G>C	non_coding_transcript_exon_variant	0.21	capreomycin
rrl	1475488	n.1831G>C	non_coding_transcript_exon_variant	0.21	linezolid
rrl	1475499	n.1842C>T	non_coding_transcript_exon_variant	0.57	capreomycin	Uncertain significance
rrl	1475499	n.1842C>T	non_coding_transcript_exon_variant	0.57	linezolid	Uncertain significance
rrl	1475515	n.1858G>A	non_coding_transcript_exon_variant	0.46	capreomycin
rrl	1475515	n.1858G>A	non_coding_transcript_exon_variant	0.46	linezolid
rrl	1475518	n.1861A>G	non_coding_transcript_exon_variant	0.21	capreomycin	Uncertain significance
rrl	1475518	n.1861A>G	non_coding_transcript_exon_variant	0.21	linezolid	Uncertain significance
rrl	1475521	n.1864T>C	non_coding_transcript_exon_variant	0.18	capreomycin
rrl	1475521	n.1864T>C	non_coding_transcript_exon_variant	0.18	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.61	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.61	linezolid	Uncertain significance
rrl	1475529	n.1872A>G	non_coding_transcript_exon_variant	0.18	capreomycin
rrl	1475529	n.1872A>G	non_coding_transcript_exon_variant	0.18	linezolid
rrl	1475531	n.1874C>T	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1475531	n.1874C>T	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1475538	n.1881T>A	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1475538	n.1881T>A	non_coding_transcript_exon_variant	0.65	linezolid	Uncertain significance
rrl	1475539	n.1882A>T	non_coding_transcript_exon_variant	0.57	capreomycin	Uncertain significance
rrl	1475539	n.1882A>T	non_coding_transcript_exon_variant	0.57	linezolid	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1475548	n.1891C>T	non_coding_transcript_exon_variant	0.71	capreomycin
rrl	1475548	n.1891C>T	non_coding_transcript_exon_variant	0.71	linezolid
rrl	1475549	n.1892T>C	non_coding_transcript_exon_variant	0.71	capreomycin
rrl	1475549	n.1892T>C	non_coding_transcript_exon_variant	0.71	linezolid
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	0.22	capreomycin	Uncertain significance
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	0.22	linezolid
rrl	1475649	n.1992A>G	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1475649	n.1992A>G	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1475655	n.1998T>G	non_coding_transcript_exon_variant	0.73	capreomycin	Uncertain significance
rrl	1475655	n.1998T>G	non_coding_transcript_exon_variant	0.73	linezolid
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1475672	n.2015C>T	non_coding_transcript_exon_variant	0.41	capreomycin	Uncertain significance
rrl	1475672	n.2015C>T	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1475673	n.2016T>C	non_coding_transcript_exon_variant	0.43	capreomycin	Uncertain significance
rrl	1475673	n.2016T>C	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1475686	n.2029C>G	non_coding_transcript_exon_variant	0.2	capreomycin
rrl	1475686	n.2029C>G	non_coding_transcript_exon_variant	0.2	linezolid
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1475696	n.2039T>C	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475699	n.2042C>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.54	capreomycin	Uncertain significance
rrl	1475703	n.2046A>G	non_coding_transcript_exon_variant	0.54	linezolid	Uncertain significance
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.18	capreomycin
rrl	1475715	n.2058G>C	non_coding_transcript_exon_variant	0.18	linezolid
rrl	1475722	n.2065G>T	non_coding_transcript_exon_variant	0.39	capreomycin
rrl	1475722	n.2065G>T	non_coding_transcript_exon_variant	0.39	linezolid
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	0.59	capreomycin
rrl	1475751	n.2094C>A	non_coding_transcript_exon_variant	0.59	linezolid
rrl	1475751	n.2094C>T	non_coding_transcript_exon_variant	0.39	capreomycin
rrl	1475751	n.2094C>T	non_coding_transcript_exon_variant	0.39	linezolid
rrl	1475752	n.2095C>T	non_coding_transcript_exon_variant	0.36	capreomycin	Uncertain significance
rrl	1475752	n.2095C>T	non_coding_transcript_exon_variant	0.36	linezolid	Uncertain significance
rrl	1475753	n.2096C>G	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1475753	n.2096C>G	non_coding_transcript_exon_variant	0.38	linezolid
rrl	1475754	n.2097G>A	non_coding_transcript_exon_variant	0.37	capreomycin
rrl	1475754	n.2097G>A	non_coding_transcript_exon_variant	0.37	linezolid
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.62	capreomycin
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.62	linezolid
rrl	1475758	n.2101_2104delACCC	non_coding_transcript_exon_variant	0.6	capreomycin
rrl	1475758	n.2101_2104delACCC	non_coding_transcript_exon_variant	0.6	linezolid
rrl	1475758	n.2105G>C	non_coding_transcript_exon_variant	0.37	capreomycin
rrl	1475758	n.2105G>C	non_coding_transcript_exon_variant	0.37	linezolid
rrl	1475763	n.2107_2108delAA	non_coding_transcript_exon_variant	0.51	capreomycin
rrl	1475763	n.2107_2108delAA	non_coding_transcript_exon_variant	0.51	linezolid
rrl	1475769	n.2112T>C	non_coding_transcript_exon_variant	0.38	capreomycin
rrl	1475769	n.2112T>C	non_coding_transcript_exon_variant	0.38	linezolid
rrl	1475774	n.2117C>T	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1475774	n.2117C>T	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1475775	n.2118G>T	non_coding_transcript_exon_variant	0.41	capreomycin	Uncertain significance
rrl	1475775	n.2118G>T	non_coding_transcript_exon_variant	0.41	linezolid	Uncertain significance
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.59	capreomycin
rrl	1475777	n.2120A>T	non_coding_transcript_exon_variant	0.59	linezolid
rrl	1475869	n.2212C>A	non_coding_transcript_exon_variant	0.5	capreomycin
rrl	1475869	n.2212C>A	non_coding_transcript_exon_variant	0.5	linezolid
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.79	capreomycin
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	0.79	linezolid
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	0.35	capreomycin	Uncertain significance
rrl	1475883	n.2226A>C	non_coding_transcript_exon_variant	0.35	linezolid
rrl	1475883	n.2226A>T	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1475883	n.2226A>T	non_coding_transcript_exon_variant	0.65	linezolid	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.34	capreomycin	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.34	linezolid	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475898	n.2241A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475899	n.2242G>A	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475900	n.2243A>G	non_coding_transcript_exon_variant	0.25	capreomycin	Uncertain significance
rrl	1475900	n.2243A>G	non_coding_transcript_exon_variant	0.25	linezolid
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475916	n.2259C>G	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1475937	n.2280A>T	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475943	n.2286G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.4	capreomycin
rrl	1475945	n.2288C>A	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1475952	n.2295A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1475963	n.2306G>T	non_coding_transcript_exon_variant	0.6	capreomycin
rrl	1475963	n.2306G>T	non_coding_transcript_exon_variant	0.6	linezolid
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1475970	n.2313C>T	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1475975	n.2318C>T	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475977	n.2320A>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475978	n.2321C>T	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1475978	n.2321C>T	non_coding_transcript_exon_variant	0.62	linezolid	Uncertain significance
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.96	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1475993	n.2336C>T	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1475993	n.2336C>T	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1475997	n.2340A>T	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1475997	n.2340A>T	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1475998	n.2341C>T	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1475998	n.2341C>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476001	n.2344T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476001	n.2344T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.75	capreomycin
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.75	linezolid
rrl	1476034	n.2377C>G	non_coding_transcript_exon_variant	0.81	capreomycin	Uncertain significance
rrl	1476034	n.2377C>G	non_coding_transcript_exon_variant	0.81	linezolid
rrl	1476040	n.2383C>T	non_coding_transcript_exon_variant	0.77	capreomycin
rrl	1476040	n.2383C>T	non_coding_transcript_exon_variant	0.77	linezolid
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	0.77	capreomycin	Uncertain significance
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	0.77	linezolid
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.77	capreomycin
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.77	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476076	n.2419A>G	non_coding_transcript_exon_variant	0.4	capreomycin
rrl	1476076	n.2419A>G	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1476110	n.2453G>T	non_coding_transcript_exon_variant	0.64	capreomycin	Uncertain significance
rrl	1476110	n.2453G>T	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1476113	n.2456T>G	non_coding_transcript_exon_variant	0.17	capreomycin
rrl	1476113	n.2456T>G	non_coding_transcript_exon_variant	0.17	linezolid
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	0.6	linezolid	Uncertain significance
rrl	1476130	n.2473G>A	non_coding_transcript_exon_variant	0.64	capreomycin	Uncertain significance
rrl	1476130	n.2473G>A	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1476135	n.2478T>C	non_coding_transcript_exon_variant	0.15	capreomycin	Uncertain significance
rrl	1476135	n.2478T>C	non_coding_transcript_exon_variant	0.15	linezolid	Uncertain significance
rrl	1476141	n.2484A>G	non_coding_transcript_exon_variant	0.25	capreomycin	Uncertain significance
rrl	1476141	n.2484A>G	non_coding_transcript_exon_variant	0.25	linezolid	Uncertain significance
rrl	1476153	n.2496T>C	non_coding_transcript_exon_variant	0.32	capreomycin	Uncertain significance
rrl	1476153	n.2496T>C	non_coding_transcript_exon_variant	0.32	linezolid	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.72	capreomycin	Uncertain significance
rrl	1476164	n.2507A>G	non_coding_transcript_exon_variant	0.72	linezolid	Uncertain significance
rrl	1476165	n.2508T>G	non_coding_transcript_exon_variant	0.2	capreomycin	Not assoc w R
rrl	1476165	n.2508T>G	non_coding_transcript_exon_variant	0.2	linezolid	Uncertain significance
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Not assoc w R
rrl	1476194	n.2537A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476195	n.2538C>A	non_coding_transcript_exon_variant	0.28	capreomycin	Uncertain significance
rrl	1476195	n.2538C>A	non_coding_transcript_exon_variant	0.28	linezolid	Uncertain significance
rrl	1476196	n.2539C>A	non_coding_transcript_exon_variant	0.22	capreomycin	Uncertain significance
rrl	1476196	n.2539C>A	non_coding_transcript_exon_variant	0.22	linezolid	Uncertain significance
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	0.9	capreomycin	Not assoc w R
rrl	1476200	n.2543A>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.76	capreomycin	Not assoc w R
rrl	1476201	n.2544C>T	non_coding_transcript_exon_variant	0.76	linezolid	Uncertain significance
rrl	1476204	n.2547C>A	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1476204	n.2547C>A	non_coding_transcript_exon_variant	0.3	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476215	n.2558C>A	non_coding_transcript_exon_variant	0.23	capreomycin	Uncertain significance
rrl	1476215	n.2558C>A	non_coding_transcript_exon_variant	0.23	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.73	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.73	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.62	linezolid	Uncertain significance
rrl	1476225	n.2568T>G	non_coding_transcript_exon_variant	0.37	capreomycin	Uncertain significance
rrl	1476225	n.2568T>G	non_coding_transcript_exon_variant	0.37	linezolid	Uncertain significance
rrl	1476229	n.2572C>G	non_coding_transcript_exon_variant	0.27	capreomycin	Uncertain significance
rrl	1476229	n.2572C>G	non_coding_transcript_exon_variant	0.27	linezolid
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1476245	n.2588C>T	non_coding_transcript_exon_variant	0.4	linezolid	Uncertain significance
rrl	1476250	n.2593C>G	non_coding_transcript_exon_variant	0.28	capreomycin	Uncertain significance
rrl	1476250	n.2593C>G	non_coding_transcript_exon_variant	0.28	linezolid	Uncertain significance
rrl	1476251	n.2594T>C	non_coding_transcript_exon_variant	0.48	capreomycin	Uncertain significance
rrl	1476251	n.2594T>C	non_coding_transcript_exon_variant	0.48	linezolid	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.64	capreomycin	Uncertain significance
rrl	1476252	n.2595T>G	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1476253	n.2596A>G	non_coding_transcript_exon_variant	0.32	capreomycin
rrl	1476253	n.2596A>G	non_coding_transcript_exon_variant	0.32	linezolid
rrl	1476256	n.2599A>G	non_coding_transcript_exon_variant	0.59	capreomycin	Uncertain significance
rrl	1476256	n.2599A>G	non_coding_transcript_exon_variant	0.59	linezolid	Uncertain significance
rrl	1476257	n.2600G>C	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1476257	n.2600G>C	non_coding_transcript_exon_variant	0.3	linezolid	Uncertain significance
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476280	n.2623A>C	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1476280	n.2623A>C	non_coding_transcript_exon_variant	0.68	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.31	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.31	linezolid	Uncertain significance
rrl	1476293	n.2636C>T	non_coding_transcript_exon_variant	0.7	capreomycin	Uncertain significance
rrl	1476293	n.2636C>T	non_coding_transcript_exon_variant	0.7	linezolid	Uncertain significance
rrl	1476294	n.2637A>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476294	n.2637A>G	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476295	n.2638C>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476295	n.2638C>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476296	n.2639C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476296	n.2639C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476297	n.2640C>G	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1476297	n.2640C>G	non_coding_transcript_exon_variant	0.4	linezolid	Uncertain significance
rrl	1476297	n.2640C>T	non_coding_transcript_exon_variant	0.5	capreomycin	Uncertain significance
rrl	1476297	n.2640C>T	non_coding_transcript_exon_variant	0.5	linezolid	Uncertain significance
rrl	1476299	n.2642C>G	non_coding_transcript_exon_variant	0.18	capreomycin
rrl	1476299	n.2642C>G	non_coding_transcript_exon_variant	0.18	linezolid
rrl	1476300	n.2643G>T	non_coding_transcript_exon_variant	0.18	capreomycin
rrl	1476300	n.2643G>T	non_coding_transcript_exon_variant	0.18	linezolid
rrl	1476301	n.2644A>T	non_coding_transcript_exon_variant	0.64	capreomycin	Uncertain significance
rrl	1476301	n.2644A>T	non_coding_transcript_exon_variant	0.64	linezolid	Uncertain significance
rrl	1476302	n.2645G>A	non_coding_transcript_exon_variant	0.4	capreomycin	Uncertain significance
rrl	1476302	n.2645G>A	non_coding_transcript_exon_variant	0.4	linezolid	Uncertain significance
rrl	1476308	n.2651G>C	non_coding_transcript_exon_variant	0.18	capreomycin
rrl	1476308	n.2651G>C	non_coding_transcript_exon_variant	0.18	linezolid
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1476311	n.2654G>C	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1476312	n.2655T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1476312	n.2655T>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1476313	n.2656G>A	non_coding_transcript_exon_variant	0.67	capreomycin	Uncertain significance
rrl	1476313	n.2656G>A	non_coding_transcript_exon_variant	0.67	linezolid	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.69	capreomycin	Uncertain significance
rrl	1476332	n.2675G>C	non_coding_transcript_exon_variant	0.69	linezolid	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.66	capreomycin	Uncertain significance
rrl	1476338	n.2681C>T	non_coding_transcript_exon_variant	0.66	linezolid	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.59	capreomycin	Uncertain significance
rrl	1476353	n.2696G>T	non_coding_transcript_exon_variant	0.59	linezolid	Uncertain significance
rrl	1476357	n.2700T>C	non_coding_transcript_exon_variant	0.21	capreomycin
rrl	1476357	n.2700T>C	non_coding_transcript_exon_variant	0.21	linezolid
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.77	capreomycin	Uncertain significance
rrl	1476358	n.2701T>C	non_coding_transcript_exon_variant	0.77	linezolid	Uncertain significance
rrl	1476359	n.2702C>G	non_coding_transcript_exon_variant	0.23	capreomycin	Uncertain significance
rrl	1476359	n.2702C>G	non_coding_transcript_exon_variant	0.23	linezolid	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.61	capreomycin	Uncertain significance
rrl	1476369	n.2712C>T	non_coding_transcript_exon_variant	0.61	linezolid	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.53	capreomycin	Uncertain significance
rrl	1476372	n.2715T>C	non_coding_transcript_exon_variant	0.53	linezolid	Uncertain significance
rrl	1476381	n.2724G>C	non_coding_transcript_exon_variant	0.19	capreomycin	Uncertain significance
rrl	1476381	n.2724G>C	non_coding_transcript_exon_variant	0.19	linezolid	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.78	capreomycin	Uncertain significance
rrl	1476382	n.2725A>G	non_coding_transcript_exon_variant	0.78	linezolid	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.67	capreomycin	Uncertain significance
rrl	1476383	n.2726T>A	non_coding_transcript_exon_variant	0.67	linezolid	Uncertain significance
rrl	1476408	n.2751G>A	non_coding_transcript_exon_variant	0.21	capreomycin	Uncertain significance
rrl	1476408	n.2751G>A	non_coding_transcript_exon_variant	0.21	linezolid	Uncertain significance
rrl	1476411	n.2754G>A	non_coding_transcript_exon_variant	0.24	capreomycin
rrl	1476411	n.2754G>A	non_coding_transcript_exon_variant	0.24	linezolid
rrl	1476425	n.2768G>T	non_coding_transcript_exon_variant	0.56	capreomycin	Uncertain significance
rrl	1476425	n.2768G>T	non_coding_transcript_exon_variant	0.56	linezolid	Uncertain significance
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.87	capreomycin	Not assoc w R
rrl	1476428	n.2771C>T	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.63	capreomycin	Uncertain significance
rrl	1476429	n.2772A>C	non_coding_transcript_exon_variant	0.63	linezolid	Uncertain significance
rrl	1476463	n.2806C>T	non_coding_transcript_exon_variant	0.19	capreomycin
rrl	1476463	n.2806C>T	non_coding_transcript_exon_variant	0.19	linezolid
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.43	capreomycin	Not assoc w R
rrl	1476466	n.2809C>T	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.86	capreomycin	Not assoc w R
rrl	1476481	n.2824T>C	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.93	capreomycin	Not assoc w R
rrl	1476506	n.2849T>C	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.27	capreomycin
rrl	1476513	n.2856G>T	non_coding_transcript_exon_variant	0.27	linezolid
rrl	1476514	n.2857C>T	non_coding_transcript_exon_variant	0.45	capreomycin	Uncertain significance
rrl	1476514	n.2857C>T	non_coding_transcript_exon_variant	0.45	linezolid	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.55	capreomycin	Uncertain significance
rrl	1476515	n.2858C>T	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.38	capreomycin	Uncertain significance
rrl	1476519	n.2862C>G	non_coding_transcript_exon_variant	0.38	linezolid	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.24	capreomycin	Uncertain significance
rrl	1476523	n.2866T>C	non_coding_transcript_exon_variant	0.24	linezolid	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	0.43	capreomycin	Uncertain significance
rrl	1476524	n.2867C>A	non_coding_transcript_exon_variant	0.43	linezolid	Uncertain significance
rrl	1476524	n.2867C>T	non_coding_transcript_exon_variant	0.55	capreomycin
rrl	1476524	n.2867C>T	non_coding_transcript_exon_variant	0.55	linezolid
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476525	n.2868A>G	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476528	n.2871A>G	non_coding_transcript_exon_variant	0.3	capreomycin	Uncertain significance
rrl	1476528	n.2871A>G	non_coding_transcript_exon_variant	0.3	linezolid
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	0.51	capreomycin	Uncertain significance
rrl	1476530	n.2873C>T	non_coding_transcript_exon_variant	0.51	linezolid	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476536	n.2879G>A	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476538	n.2881A>G	non_coding_transcript_exon_variant	0.61	capreomycin	Uncertain significance
rrl	1476538	n.2881A>G	non_coding_transcript_exon_variant	0.61	linezolid	Uncertain significance
rrl	1476539	n.2882A>G	non_coding_transcript_exon_variant	0.74	capreomycin	Uncertain significance
rrl	1476539	n.2882A>G	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1476540	n.2883C>G	non_coding_transcript_exon_variant	0.56	capreomycin	Uncertain significance
rrl	1476540	n.2883C>G	non_coding_transcript_exon_variant	0.56	linezolid	Uncertain significance
rrl	1476547	n.2890C>T	non_coding_transcript_exon_variant	0.49	capreomycin	Uncertain significance
rrl	1476547	n.2890C>T	non_coding_transcript_exon_variant	0.49	linezolid	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	0.2	capreomycin	Uncertain significance
rrl	1476567	n.2910C>T	non_coding_transcript_exon_variant	0.2	linezolid	Uncertain significance
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.87	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.87	linezolid	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.77	capreomycin	Uncertain significance
rrl	1476585	n.2928A>G	non_coding_transcript_exon_variant	0.77	linezolid	Uncertain significance
rrl	1476600	n.2943A>C	non_coding_transcript_exon_variant	0.47	capreomycin
rrl	1476600	n.2943A>C	non_coding_transcript_exon_variant	0.47	linezolid
rrl	1476603	n.2946G>T	non_coding_transcript_exon_variant	0.19	capreomycin
rrl	1476603	n.2946G>T	non_coding_transcript_exon_variant	0.19	linezolid
rrl	1476607	n.2950C>T	non_coding_transcript_exon_variant	0.23	capreomycin	Uncertain significance
rrl	1476607	n.2950C>T	non_coding_transcript_exon_variant	0.23	linezolid	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.79	capreomycin	Uncertain significance
rrl	1476608	n.2951C>G	non_coding_transcript_exon_variant	0.79	linezolid	Uncertain significance
rrl	1476613	n.2956G>A	non_coding_transcript_exon_variant	0.22	capreomycin
rrl	1476613	n.2956G>A	non_coding_transcript_exon_variant	0.22	linezolid
rrl	1476614	n.2957A>T	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1476614	n.2957A>T	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476616	n.2959A>G	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1476616	n.2959A>G	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.74	capreomycin	Not assoc w R
rrl	1476619	n.2962C>T	non_coding_transcript_exon_variant	0.74	linezolid	Uncertain significance
rrl	1476628	n.2971T>G	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1476628	n.2971T>G	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1476629	n.2972C>A	non_coding_transcript_exon_variant	0.75	capreomycin	Uncertain significance
rrl	1476629	n.2972C>A	non_coding_transcript_exon_variant	0.75	linezolid
rrl	1476630	n.2973A>G	non_coding_transcript_exon_variant	0.37	capreomycin	Uncertain significance
rrl	1476630	n.2973A>G	non_coding_transcript_exon_variant	0.37	linezolid	Uncertain significance
rrl	1476630	n.2976A>G	non_coding_transcript_exon_variant	0.4	capreomycin
rrl	1476630	n.2976A>G	non_coding_transcript_exon_variant	0.4	linezolid
rrl	1476664	n.3007T>A	non_coding_transcript_exon_variant	0.49	capreomycin
rrl	1476664	n.3007T>A	non_coding_transcript_exon_variant	0.49	linezolid
rrl	1476668	n.3011C>T	non_coding_transcript_exon_variant	0.46	capreomycin
rrl	1476668	n.3011C>T	non_coding_transcript_exon_variant	0.46	linezolid
rrl	1476675	n.3018C>A	non_coding_transcript_exon_variant	0.28	capreomycin
rrl	1476675	n.3018C>A	non_coding_transcript_exon_variant	0.28	linezolid
rpsA	1833641	p.Asn34Asp	missense_variant	0.39	pyrazinamide
rpsA	1833646	c.105T>C	synonymous_variant	0.44	pyrazinamide	Not assoc w R - Interim
rpsA	1833652	c.111C>T	synonymous_variant	0.45	pyrazinamide
rpsA	1833661	c.120A>G	synonymous_variant	0.62	pyrazinamide
rpsA	1833667	c.126C>T	synonymous_variant	0.61	pyrazinamide
rpsA	1833668	p.Ile43Val	missense_variant	0.68	pyrazinamide
rpsA	1833676	c.135A>G	synonymous_variant	0.69	pyrazinamide
rpsA	1833679	c.138G>C	synonymous_variant	0.7	pyrazinamide
rpsA	1833685	c.144G>T	synonymous_variant	0.65	pyrazinamide
rpsA	1833688	c.147C>T	synonymous_variant	0.65	pyrazinamide
rpsA	1833694	c.153G>C	synonymous_variant	0.75	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	0.79	pyrazinamide
rpsA	1833732	p.Pro64Leu	missense_variant	0.8	pyrazinamide
rpsA	1833736	c.195C>T	synonymous_variant	0.8	pyrazinamide
rpsA	1833742	c.201A>G	synonymous_variant	0.76	pyrazinamide
rpsA	1833770	p.Asn77Asp	missense_variant	0.85	pyrazinamide
rpsA	1833776	p.Val79Ile	missense_variant	0.83	pyrazinamide
rpsA	1833781	c.240T>C	synonymous_variant	0.45	pyrazinamide
rpsA	1833790	c.249T>C	synonymous_variant	0.57	pyrazinamide
rpsA	1833797	p.Val86Ile	missense_variant	0.74	pyrazinamide	Uncertain significance
rpsA	1833802	c.261A>G	synonymous_variant	0.22	pyrazinamide
rpsA	1833808	c.267G>C	synonymous_variant	0.31	pyrazinamide
rpsA	1833811	c.270G>C	synonymous_variant	0.36	pyrazinamide
rpsA	1833815	p.Thr92Gln	missense_variant	0.3	pyrazinamide
rpsA	1833829	c.288A>G	synonymous_variant	0.28	pyrazinamide
rpsA	1833838	c.297G>C	synonymous_variant	0.19	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	0.2	pyrazinamide
rpsA	1833842	p.Ile101Leu	missense_variant	0.18	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	0.18	pyrazinamide
rpsA	1833849	p.Ser103Cys	missense_variant	0.21	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	0.45	pyrazinamide
rpsA	1833859	c.318C>T	synonymous_variant	0.19	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	0.6	pyrazinamide
rpsA	1833893	p.AlaLeu118ArgIle	missense_variant	0.58	pyrazinamide
rpsA	1833905	p.Lys122Glu	missense_variant	0.59	pyrazinamide
rpsA	1833912	p.Glu124Gly	missense_variant	0.62	pyrazinamide
rpsA	1833915	p.Ala125Val	missense_variant	0.63	pyrazinamide	Uncertain significance
rpsA	1833921	p.Lys127Thr	missense_variant	0.63	pyrazinamide
rpsA	1833926	p.Thr129Ser	missense_variant	0.59	pyrazinamide
rpsA	1833940	c.399C>T	synonymous_variant	0.24	pyrazinamide
rpsA	1833949	c.408T>C	synonymous_variant	0.47	pyrazinamide
rpsA	1833952	c.411C>T	synonymous_variant	0.52	pyrazinamide
rpsA	1833955	c.414G>C	synonymous_variant	0.65	pyrazinamide
rpsA	1833955	c.414G>T	synonymous_variant	0.23	pyrazinamide
rpsA	1833961	c.420C>G	synonymous_variant	0.41	pyrazinamide
rpsA	1833970	c.429G>C	synonymous_variant	0.51	pyrazinamide
rpsA	1833970	c.429G>T	synonymous_variant	0.36	pyrazinamide
rpsA	1833976	c.435C>T	synonymous_variant	0.3	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	0.79	pyrazinamide
rpsA	1833991	c.450C>A	synonymous_variant	0.33	pyrazinamide
rpsA	1833994	c.453G>C	synonymous_variant	0.89	pyrazinamide
rpsA	1833997	c.456G>C	synonymous_variant	0.27	pyrazinamide
rpsA	1834000	c.459G>T	synonymous_variant	0.35	pyrazinamide
rpsA	1834009	c.468C>T	synonymous_variant	0.6	pyrazinamide
rpsA	1834012	c.471G>C	synonymous_variant	0.87	pyrazinamide
rpsA	1834015	c.474G>C	synonymous_variant	0.38	pyrazinamide
rpsA	1834015	c.474G>T	synonymous_variant	0.37	pyrazinamide
rpsA	1834024	c.482_483insC	frameshift_variant	0.26	pyrazinamide	Uncertain significance
rpsA	1834024	c.483G>C	synonymous_variant	0.57	pyrazinamide
rpsA	1834026	c.486delG	frameshift_variant	0.21	pyrazinamide	Uncertain significance
rpsA	1834030	c.489C>T	synonymous_variant	0.2	pyrazinamide
rpsA	1834034	p.Ile165Val	missense_variant	0.58	pyrazinamide
rpsA	1834039	c.498C>T	synonymous_variant	0.22	pyrazinamide
rpsA	1834040	p.Lys167Arg	missense_variant	0.86	pyrazinamide
rpsA	1834043	p.Glu168Gln	missense_variant	0.28	pyrazinamide
rpsA	1834046	p.Ile169Leu	missense_variant	0.66	pyrazinamide
rpsA	1834051	c.510G>A	synonymous_variant	0.28	pyrazinamide
rpsA	1834054	c.513C>G	synonymous_variant	0.61	pyrazinamide
rpsA	1834063	c.522C>T	synonymous_variant	0.33	pyrazinamide
rpsA	1834090	c.549G>T	synonymous_variant	0.18	pyrazinamide
rpsA	1834093	c.552G>C	synonymous_variant	0.66	pyrazinamide
rpsA	1834096	c.555G>C	synonymous_variant	0.5	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	0.28	pyrazinamide
rpsA	1834114	c.573G>C	synonymous_variant	0.47	pyrazinamide
rpsA	1834123	c.582C>T	synonymous_variant	0.28	pyrazinamide
rpsA	1834135	c.594G>C	synonymous_variant	0.15	pyrazinamide
rpsA	1834195	c.654G>C	synonymous_variant	0.49	pyrazinamide
rpsA	1834210	c.669C>T	synonymous_variant	0.49	pyrazinamide
rpsA	1834213	c.672G>C	synonymous_variant	0.46	pyrazinamide
rpsA	1834219	c.678C>G	synonymous_variant	0.45	pyrazinamide
rpsA	1834222	c.681T>C	synonymous_variant	0.5	pyrazinamide
rpsA	1834225	c.684C>G	synonymous_variant	0.42	pyrazinamide
rpsA	1834228	c.687C>T	synonymous_variant	0.51	pyrazinamide
rpsA	1834231	c.690T>C	synonymous_variant	0.47	pyrazinamide
rpsA	1834234	c.693G>C	synonymous_variant	0.41	pyrazinamide
rpsA	1834246	c.705G>C	synonymous_variant	0.53	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	0.66	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	0.69	pyrazinamide	Not assoc w R - Interim
rpsA	1834264	c.723G>C	synonymous_variant	0.66	pyrazinamide
rpsA	1834285	c.744G>C	synonymous_variant	0.57	pyrazinamide
rpsA	1834294	c.753G>C	synonymous_variant	0.64	pyrazinamide
rpsA	1834298	p.Gln253Glu	missense_variant	0.69	pyrazinamide
rpsA	1834303	c.762T>C	synonymous_variant	0.49	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	0.53	pyrazinamide
rpsA	1834307	p.Asp256Lys	missense_variant	0.6	pyrazinamide
rpsA	1834312	c.771G>A	synonymous_variant	0.21	pyrazinamide
rpsA	1834318	c.777C>G	synonymous_variant	0.44	pyrazinamide	Not assoc w R - Interim
rpsA	1834327	c.786G>C	synonymous_variant	0.49	pyrazinamide
rpsA	1834330	c.789C>G	synonymous_variant	0.58	pyrazinamide
rpsA	1834340	p.Met267Phe	missense_variant	0.38	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	0.51	pyrazinamide	Not assoc w R - Interim
rpsA	1834354	c.813G>C	synonymous_variant	0.47	pyrazinamide	Not assoc w R - Interim
rpsA	1834357	c.816T>C	synonymous_variant	0.43	pyrazinamide
rpsA	1834360	c.819G>C	synonymous_variant	0.38	pyrazinamide
rpsA	1834361	c.820T>C	synonymous_variant	0.47	pyrazinamide
rpsA	1834366	c.825A>G	synonymous_variant	0.48	pyrazinamide	Not assoc w R - Interim
rpsA	1834378	c.837T>C	synonymous_variant	0.33	pyrazinamide	Not assoc w R - Interim
rpsA	1834384	c.843A>G	synonymous_variant	0.33	pyrazinamide
rpsA	1834423	c.882G>C	synonymous_variant	0.18	pyrazinamide
rpsA	1834435	c.894G>C	synonymous_variant	0.18	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	0.21	pyrazinamide
rpsA	1834459	c.918G>C	synonymous_variant	0.26	pyrazinamide
rpsA	1834468	c.927A>C	synonymous_variant	0.34	pyrazinamide
rpsA	1834474	c.933C>G	synonymous_variant	0.19	pyrazinamide
rpsA	1834477	c.936C>T	synonymous_variant	0.2	pyrazinamide	Not assoc w R - Interim
rpsA	1834486	p.Glu315Asp	missense_variant	0.48	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	0.45	pyrazinamide
rpsA	1834504	c.963G>C	synonymous_variant	0.5	pyrazinamide
rpsA	1834522	c.981C>G	synonymous_variant	0.43	pyrazinamide
rpsA	1834523	p.Glu328Gln	missense_variant	0.57	pyrazinamide
rpsA	1834528	c.987T>C	synonymous_variant	0.18	pyrazinamide
rpsA	1834540	c.999G>C	synonymous_variant	0.39	pyrazinamide
rpsA	1834546	p.Asp335Glu	missense_variant	0.55	pyrazinamide
rpsA	1834552	c.1013_1015delTTG	disruptive_inframe_deletion	0.47	pyrazinamide
rpsA	1834558	c.1017_1018insAAG	conservative_inframe_insertion	0.54	pyrazinamide
rpsA	1834570	p.Asp343Glu	missense_variant	0.52	pyrazinamide
rpsA	1834572	p.Ala344Val	missense_variant	0.53	pyrazinamide
rpsA	1834574	p.Met345Phe	missense_variant	0.54	pyrazinamide
rpsA	1834612	c.1071G>C	synonymous_variant	0.46	pyrazinamide
rpsA	1834618	c.1077G>C	synonymous_variant	0.36	pyrazinamide
rpsA	1834619	c.1078T>C	synonymous_variant	0.36	pyrazinamide
rpsA	1834627	c.1086C>G	synonymous_variant	0.19	pyrazinamide
rpsA	1834633	c.1092A>G	synonymous_variant	0.25	pyrazinamide
tsnR	1854300	p.Leu232Pro	missense_variant	1.0	linezolid	Not assoc w R
tlyA	1917972	c.33A>G	synonymous_variant	1.0	capreomycin	Not assoc w R
Rv1979c	2223051	p.Glu38Asp	missense_variant	1.0	bedaquiline	Uncertain significance
Rv1979c	2223051	p.Glu38Asp	missense_variant	1.0	clofazimine	Uncertain significance
Rv1979c	2223293	c.-129A>G	upstream_gene_variant	1.0	bedaquiline	Not assoc w R - Interim
Rv1979c	2223293	c.-129A>G	upstream_gene_variant	1.0	clofazimine	Not assoc w R
kasA	2518919	p.Gly269Ser	missense_variant	0.98	isoniazid
Rv2752c	3065824	p.Pro123Leu	missense_variant	1.0	levofloxacin	Not assoc w R
					moxifloxacin	Uncertain significance
					isoniazid	Not assoc w R - Interim
					rifampicin	Not assoc w R
					ethambutol	Not assoc w R
thyA	3073868	p.Thr202Ala	missense_variant	0.99	para-aminosalicylic_acid
ald	3086788	c.-32T>C	upstream_gene_variant	1.0	cycloserine
mtrB	3625065	p.Met517Leu	missense_variant	1.0	rifampicin	Not assoc w R
mtrB	3625065	p.Met517Leu	missense_variant	1.0	bedaquiline	Uncertain significance
clpC1	4038287	c.2418C>T	synonymous_variant	1.0	pyrazinamide	Not assoc w R
clpC1	4039670	p.Val345Ile	missense_variant	0.19	pyrazinamide
clpC1	4039694	c.1011G>T	synonymous_variant	0.45	pyrazinamide
clpC1	4039709	c.996C>T	synonymous_variant	0.42	pyrazinamide
clpC1	4039714	p.Tyr331His	missense_variant	0.42	pyrazinamide
clpC1	4039730	c.975C>G	synonymous_variant	0.44	pyrazinamide
clpC1	4039733	c.972G>C	synonymous_variant	0.44	pyrazinamide
clpC1	4039739	c.966C>A	synonymous_variant	0.41	pyrazinamide
clpC1	4039742	c.963C>T	synonymous_variant	0.43	pyrazinamide
clpC1	4039748	c.957G>C	synonymous_variant	0.43	pyrazinamide
clpC1	4039751	c.954A>G	synonymous_variant	0.44	pyrazinamide
clpC1	4039760	c.945T>C	synonymous_variant	0.45	pyrazinamide
clpC1	4039763	c.942C>A	synonymous_variant	0.42	pyrazinamide
clpC1	4039769	c.936C>G	synonymous_variant	0.45	pyrazinamide
clpC1	4039773	p.Lys311Met	missense_variant	0.45	pyrazinamide
clpC1	4039775	c.930G>C	synonymous_variant	0.44	pyrazinamide
clpC1	4039778	c.927A>G	synonymous_variant	0.46	pyrazinamide
clpC1	4039781	c.924G>C	synonymous_variant	0.48	pyrazinamide
clpC1	4039787	c.918G>C	synonymous_variant	0.5	pyrazinamide
clpC1	4039793	c.912C>T	synonymous_variant	0.44	pyrazinamide
clpC1	4039799	c.906C>T	synonymous_variant	0.46	pyrazinamide
clpC1	4039811	c.894C>A	synonymous_variant	0.43	pyrazinamide
clpC1	4039817	c.888A>T	synonymous_variant	0.37	pyrazinamide
clpC1	4039820	c.885T>A	synonymous_variant	0.3	pyrazinamide
clpC1	4039826	c.879C>T	synonymous_variant	0.2	pyrazinamide
clpC1	4039829	c.874_876delTTGinsCTC	synonymous_variant	0.26	pyrazinamide
clpC1	4039838	p.Leu289Ile	missense_variant	0.3	pyrazinamide
clpC1	4039847	c.858C>T	synonymous_variant	0.18	pyrazinamide
clpC1	4039850	c.855T>C	synonymous_variant	0.33	pyrazinamide
clpC1	4039865	c.840T>C	synonymous_variant	0.31	pyrazinamide
clpC1	4039873	p.Thr278Ser	missense_variant	0.25	pyrazinamide	Uncertain significance
clpC1	4039875	p.Asn277Arg	missense_variant	0.28	pyrazinamide
clpC1	4039880	c.825G>A	synonymous_variant	0.24	pyrazinamide
clpC1	4039886	c.819C>G	synonymous_variant	0.28	pyrazinamide
clpC1	4039889	c.816G>C	synonymous_variant	0.34	pyrazinamide
clpC1	4039898	c.807C>G	synonymous_variant	0.36	pyrazinamide
clpC1	4039904	c.801A>G	synonymous_variant	0.41	pyrazinamide
clpC1	4039907	c.798G>A	synonymous_variant	0.37	pyrazinamide	Not assoc w R - Interim
clpC1	4039982	c.723G>C	synonymous_variant	0.35	pyrazinamide
clpC1	4039991	c.714G>C	synonymous_variant	0.32	pyrazinamide
clpC1	4039994	p.Glu237Asp	missense_variant	0.37	pyrazinamide
clpC1	4039997	c.708C>T	synonymous_variant	0.32	pyrazinamide	Not assoc w R - Interim
clpC1	4040009	c.696C>T	synonymous_variant	0.52	pyrazinamide
clpC1	4040015	c.690G>A	synonymous_variant	0.61	pyrazinamide	Not assoc w R - Interim
clpC1	4040021	c.684A>C	synonymous_variant	0.66	pyrazinamide	Not assoc w R - Interim
clpC1	4040024	c.681A>G	synonymous_variant	0.66	pyrazinamide
clpC1	4040027	c.678C>G	synonymous_variant	0.54	pyrazinamide
clpC1	4040033	c.672G>C	synonymous_variant	0.69	pyrazinamide
clpC1	4040042	c.663C>T	synonymous_variant	0.54	pyrazinamide	Not assoc w R - Interim
clpC1	4040057	c.648C>T	synonymous_variant	0.64	pyrazinamide
clpC1	4040060	c.645C>T	synonymous_variant	0.53	pyrazinamide
clpC1	4040063	c.642G>C	synonymous_variant	0.19	pyrazinamide	Not assoc w R - Interim
clpC1	4040066	c.639G>C	synonymous_variant	0.19	pyrazinamide
clpC1	4040069	c.636G>C	synonymous_variant	0.73	pyrazinamide
clpC1	4040084	c.621C>T	synonymous_variant	0.54	pyrazinamide
clpC1	4040087	c.618G>C	synonymous_variant	0.56	pyrazinamide
clpC1	4040090	c.615T>C	synonymous_variant	0.75	pyrazinamide	Not assoc w R - Interim
clpC1	4040096	c.609G>C	synonymous_variant	0.75	pyrazinamide
clpC1	4040108	c.597G>C	synonymous_variant	0.58	pyrazinamide
clpC1	4040111	c.594G>A	synonymous_variant	0.59	pyrazinamide	Not assoc w R - Interim
clpC1	4040114	p.Ile197Met	missense_variant	0.74	pyrazinamide
clpC1	4040117	c.588A>G	synonymous_variant	0.76	pyrazinamide
clpC1	4040123	p.Glu194His	missense_variant	0.6	pyrazinamide
clpC1	4040147	c.558A>G	synonymous_variant	0.5	pyrazinamide	Not assoc w R - Interim
whiB6	4338595	c.-75delG	upstream_gene_variant	1.0	kanamycin	Not assoc w R
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
whiB6	4338732	c.-211C>T	upstream_gene_variant	1.0	kanamycin
					capreomycin
					amikacin
gid	4408156	p.Leu16Arg	missense_variant	1.0	streptomycin	Not assoc w R