TB-Profiler result

Run: SRR7535086
Summary

Run ID: SRR7535086

Sample name:

Date: 2024-05-22T15:47:57.668621

Number of reads: 6633972

Percentage reads mapped: 48.55

Median coverage: 90.0

Strain:

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.15
lineage6.2.3 West-Africa 2 RD702 0.09
lineage4.6.1 Euro-American (Uganda) RD724 0.96
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 0.24 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.42 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance Mutation from literature
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 0.18 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.21 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.24 isoniazid
dnaA 33 c.33A>G synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 42 c.42C>T synonymous_variant 0.29 isoniazid
dnaA 51 c.51C>T synonymous_variant 0.16 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.2 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.2 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.19 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.19 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.19 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.18 isoniazid
dnaA 915 c.915C>T synonymous_variant 0.17 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.17 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.31 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.28 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.29 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.26 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.23 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.24 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.24 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.24 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.17 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.2 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.2 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.22 isoniazid
dnaA 1218 c.1218C>G synonymous_variant 0.24 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.22 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.26 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.28 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.31 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.35 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.31 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.21 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.2 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.21 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.34 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.33 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.29 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.26 isoniazid
gyrB 6100 c.861G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.27 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.2 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.19 levofloxacin Uncertain significance
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.27 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.33 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 6862 c.1623C>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>A upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 7126 c.1887G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7132 c.-170T>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7228 c.-74C>T upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7246 c.2007T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7347 c.46_48delGAAinsCG frameshift_variant&missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7539 c.238_240delACCinsGG frameshift_variant&missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 7547 c.246C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7562 c.261C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 7571 c.270G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7697 c.396C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7725 c.424C>T synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.27 levofloxacin
moxifloxacin
gyrA 7739 c.438C>T synonymous_variant 0.37 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7763 c.462T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8096 c.795T>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8106 c.805C>T synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8111 c.810G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8417 c.1116C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>A synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8780 p.Asp493Glu missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.43 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.48 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>A synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.36 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Glu missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9317 c.2016G>T synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13717 c.-159T>C upstream_gene_variant 0.18 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.18 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.2 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.22 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.27 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.26 isoniazid
fgd1 490782 c.-1G>C upstream_gene_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.29 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.42 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.15 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.19 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491173 c.391C>A synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.23 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 0.36 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491526 c.744T>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fgd1 491535 c.753G>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>A synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
mshA 575536 c.189T>C synonymous_variant 0.19 ethionamide
isoniazid
mshA 575542 c.195C>G synonymous_variant 0.17 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.18 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.17 ethionamide
isoniazid
mshA 575649 p.Val101Ala missense_variant 0.18 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.22 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.22 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.3 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.27 ethionamide
isoniazid Not assoc w R - Interim
mshA 575701 c.354G>A synonymous_variant 0.23 ethionamide
isoniazid
mshA 575704 c.357T>G synonymous_variant 0.25 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.24 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.3 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.33 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.36 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.33 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.31 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.31 ethionamide
isoniazid
mshA 575755 c.408G>A synonymous_variant 0.32 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.33 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.3 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.3 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.29 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.25 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.3 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.32 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.33 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.33 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.38 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.36 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.35 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 0.3 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.31 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.29 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.23 ethionamide
isoniazid
ccsA 619574 c.-317G>A upstream_gene_variant 0.16 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.17 capreomycin
amikacin
kanamycin
ccsA 619584 c.-307A>T upstream_gene_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.26 capreomycin
amikacin
kanamycin
ccsA 619609 c.-282G>C upstream_gene_variant 0.32 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.31 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.19 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.2 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.34 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.32 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.39 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.34 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.31 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>G synonymous_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 620682 c.792G>A synonymous_variant 0.24 capreomycin
amikacin
kanamycin
ccsA 620688 c.798G>C synonymous_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAA frameshift_variant&missense_variant 0.28 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.26 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.24 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.26 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 0.29 capreomycin
amikacin
kanamycin
Rv0565c 656052 c.1419A>C synonymous_variant 0.2 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.17 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.27 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.23 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.19 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.2 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.28 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.3 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.33 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.33 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.33 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.34 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.35 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.3 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.26 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.25 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.24 ethionamide
Rv0565c 657220 p.Ala84Val missense_variant 0.16 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.24 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.3 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.36 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.37 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.37 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.35 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.53 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.43 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.37 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.37 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.32 ethionamide Uncertain significance
Rv0565c 657340 p.Ala44Glu missense_variant 0.28 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.29 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.29 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.29 ethionamide
Rv0565c 657354 c.115_117delATCinsGG frameshift_variant&missense_variant 0.29 ethionamide Uncertain significance
Rv0565c 657363 c.108C>G synonymous_variant 0.28 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.23 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 0.37 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.37 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.33 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.31 ethionamide
Rv0565c 657670 c.-200A>T upstream_gene_variant 0.24 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.24 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.22 ethionamide
Rv0565c 657686 c.-216C>T upstream_gene_variant 0.22 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.21 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.21 ethionamide
hadA 731732 c.-198G>A upstream_gene_variant 0.2 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.27 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.34 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.33 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.33 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.35 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.31 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.21 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.19 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.17 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.2 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.23 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.26 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.26 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.26 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.5 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.53 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.53 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.53 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.55 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.56 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.47 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.43 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.43 isoniazid
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.29 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.33 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.34 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.36 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.38 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.37 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.38 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.49 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.5 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.38 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.32 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.31 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.24 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.21 rifampicin
rpoB 759624 c.-183G>A upstream_gene_variant 0.17 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.25 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.31 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.36 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.43 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.33 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.35 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.42 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.43 rifampicin
rpoB 760343 c.537G>C synonymous_variant 0.45 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.45 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.45 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.53 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.49 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 0.45 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.41 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.41 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.42 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.49 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.55 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.44 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.38 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.38 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.38 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.29 rifampicin
rpoB 760781 c.975G>C synonymous_variant 0.25 rifampicin
rpoB 760869 p.Val355Ile missense_variant 0.23 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.31 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.37 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.36 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.49 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 0.55 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.5 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.5 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.53 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.43 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 0.47 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.58 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.35 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.35 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.28 rifampicin
rpoB 761373 p.Val523His missense_variant 0.28 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.3 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.32 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.3 rifampicin
rpoB 761439 p.Asp545Ser missense_variant 0.3 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.3 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.29 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.29 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.33 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.37 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.38 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.32 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.34 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.35 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.38 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.26 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761791 p.Arg662His missense_variant 0.18 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.27 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.27 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.29 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 0.29 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.33 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.33 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.36 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.37 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.34 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.29 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.29 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.3 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.32 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.31 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.47 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.27 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.27 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.2 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.2 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.21 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 0.46 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.52 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.52 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.5 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.26 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.26 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.2 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.21 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.16 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 0.18 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.28 rifampicin
rpoC 762446 c.-924C>G upstream_gene_variant 0.35 rifampicin
rpoB 762486 p.Pro894Ala missense_variant 0.2 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.19 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.22 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.22 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.42 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.39 rifampicin Not assoc w R
rpoC 763034 c.-336C>A upstream_gene_variant 0.39 rifampicin
rpoB 763040 c.3234C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.36 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 0.38 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.35 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.35 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.25 rifampicin
rpoB 763272 c.3466C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.5 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.52 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>G synonymous_variant 0.55 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763622 p.Ala85Ser missense_variant 0.16 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 0.35 rifampicin
rpoC 763642 c.273G>T synonymous_variant 0.14 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.55 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.46 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.51 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.53 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.52 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 0.57 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.6 rifampicin
rpoC 763780 c.411C>G synonymous_variant 0.58 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.55 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.53 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.49 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.45 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.45 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.45 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.43 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.44 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.44 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.42 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.42 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.43 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.46 rifampicin
rpoC 763951 c.582G>T synonymous_variant 0.5 rifampicin
rpoC 763960 c.591T>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763991 p.Ile208Leu missense_variant 0.46 rifampicin
rpoC 763996 c.627T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764005 c.636G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.44 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.41 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.4 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.43 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.42 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.42 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.42 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 0.44 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.4 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.46 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.52 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.51 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.51 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.52 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 0.52 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>G synonymous_variant 0.47 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.38 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.42 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.44 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.28 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.28 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.28 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.39 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.46 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.52 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 0.55 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.5 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>G synonymous_variant 0.41 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.36 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764815 c.1446A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.48 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.38 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.44 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.22 rifampicin Not assoc w R
rpoC 765383 p.Met672Leu missense_variant 0.2 rifampicin Uncertain significance
rpoC 765394 c.2025G>A synonymous_variant 0.27 rifampicin
rpoC 765404 p.Leu679Val missense_variant 0.29 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.31 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.31 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.44 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.39 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.41 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.39 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.39 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 0.38 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.37 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.44 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.41 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.39 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.42 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.43 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.2 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.25 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.21 rifampicin
rpoC 766061 c.2692_2694delGTCinsCG frameshift_variant&missense_variant 0.3 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 0.32 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.31 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.29 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.24 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766168 c.2799C>G synonymous_variant 0.19 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.19 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857T>C synonymous_variant 0.19 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.17 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.18 rifampicin
rpoC 766279 c.2910C>G synonymous_variant 0.19 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.21 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.43 rifampicin
rpoC 766312 c.2943T>G synonymous_variant 0.43 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.42 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.39 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.48 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.46 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.43 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.38 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.36 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.36 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.33 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.38 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.37 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.34 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 0.39 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.35 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.35 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.26 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.25 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.25 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.24 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.33 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.38 rifampicin
rpoC 766633 c.3264G>C synonymous_variant 0.39 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.5 rifampicin
rpoC 766651 c.3282T>G synonymous_variant 0.48 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.46 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.4 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.44 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.41 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.41 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.35 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.37 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.4 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.55 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.53 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.51 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.54 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.52 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.56 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767035 c.3666G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.61 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.5 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 0.49 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.33 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.34 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.3 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.29 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.29 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776672 c.1809G>C synonymous_variant 0.2 clofazimine
bedaquiline
mmpL5 776675 c.1806G>A synonymous_variant 0.16 clofazimine
bedaquiline
mmpL5 776684 c.1797G>A synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 776694 p.Val596Thr missense_variant 0.19 clofazimine
bedaquiline
mmpL5 776738 c.1743C>T synonymous_variant 0.23 clofazimine
bedaquiline
mmpL5 776741 c.1740C>G synonymous_variant 0.19 clofazimine
bedaquiline
mmpL5 776744 c.1735_1737delCGCinsAA frameshift_variant&missense_variant 0.21 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777176 p.Glu435Asp missense_variant 0.18 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.18 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.19 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.19 clofazimine
bedaquiline
mmpL5 777212 c.1267_1269delGCCinsAG frameshift_variant&missense_variant 0.2 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777215 c.1266C>G synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 777218 c.1263G>A synonymous_variant 0.21 clofazimine
bedaquiline
mmpL5 777251 c.1230C>G synonymous_variant 0.16 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.21 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.2 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.2 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.29 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.29 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.38 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.41 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.43 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.41 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.4 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.37 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.38 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.42 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.41 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.41 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.42 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.44 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.48 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.49 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.42 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.43 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.41 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.37 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.36 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.33 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.37 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.35 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.3 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.29 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.29 streptomycin Uncertain significance
rplC 800618 c.-191T>C upstream_gene_variant 0.4 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.4 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.42 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.41 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.48 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.46 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.45 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.47 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.46 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.56 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.56 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.41 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.42 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.42 linezolid
rplC 800814 c.6A>G synonymous_variant 0.41 linezolid
rplC 800817 c.9A>T synonymous_variant 0.41 linezolid
rplC 800844 c.36T>C synonymous_variant 0.43 linezolid
rplC 800865 c.57A>G synonymous_variant 0.38 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.38 linezolid
rplC 800874 c.66A>G synonymous_variant 0.32 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 0.29 linezolid
rplC 800880 c.72A>G synonymous_variant 0.3 linezolid
rplC 800889 c.81C>G synonymous_variant 0.31 linezolid
rplC 800892 c.84G>C synonymous_variant 0.3 linezolid
rplC 800907 c.99C>G synonymous_variant 0.22 linezolid
rplC 800916 c.108A>G synonymous_variant 0.19 linezolid
rplC 801153 c.345G>C synonymous_variant 0.18 linezolid
rplC 801156 c.348T>A synonymous_variant 0.23 linezolid
rplC 801168 c.360C>G synonymous_variant 0.3 linezolid
rplC 801171 c.363A>G synonymous_variant 0.31 linezolid
rplC 801174 c.366T>C synonymous_variant 0.31 linezolid
rplC 801195 c.387G>C synonymous_variant 0.34 linezolid
rplC 801207 c.399C>T synonymous_variant 0.4 linezolid
rplC 801246 c.438C>T synonymous_variant 0.36 linezolid
rplC 801249 c.441T>C synonymous_variant 0.33 linezolid
rplC 801255 c.447C>T synonymous_variant 0.25 linezolid
rplC 801264 c.456C>T synonymous_variant 0.21 linezolid
rplC 801267 c.459A>T synonymous_variant 0.21 linezolid
rplC 801279 c.471G>C synonymous_variant 0.18 linezolid
rplC 801282 c.474G>C synonymous_variant 0.19 linezolid
rplC 801285 c.477G>C synonymous_variant 0.19 linezolid
rplC 801300 c.492C>G synonymous_variant 0.26 linezolid
rplC 801309 c.501C>G synonymous_variant 0.19 linezolid
rplC 801312 c.504G>C synonymous_variant 0.23 linezolid
rplC 801321 c.513C>T synonymous_variant 0.22 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.23 linezolid
rplC 801339 c.531T>C synonymous_variant 0.25 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.25 linezolid
rplC 801348 c.540T>G synonymous_variant 0.28 linezolid
rplC 801357 c.549T>C synonymous_variant 0.3 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.32 linezolid
rplC 801402 c.594T>C synonymous_variant 0.28 linezolid
rplC 801405 c.597T>C synonymous_variant 0.29 linezolid
rplC 801438 c.630T>C synonymous_variant 0.18 linezolid
rplC 801442 p.Ile212Val missense_variant 0.17 linezolid
fbiC 1303539 c.609G>C synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.27 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304132 p.Ala401Gly missense_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304161 p.Arg411Ser missense_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304187 c.1257T>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304223 c.1293G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304226 c.1296C>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304227 p.Met433Leu missense_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.16 clofazimine
pretomanid
delamanid
fbiC 1304535 c.1605G>A synonymous_variant 0.17 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.31 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
sigE 1365033 c.621G>A synonymous_variant 0.23 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.23 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.29 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.32 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.31 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.28 pyrazinamide
sigE 1365087 c.675A>C synonymous_variant 0.27 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.28 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 0.28 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.29 pyrazinamide
sigE 1365114 c.702G>A synonymous_variant 0.25 pyrazinamide
sigE 1365117 c.705A>C synonymous_variant 0.26 pyrazinamide
sigE 1365118 c.706C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
atpE 1460816 c.-229T>C upstream_gene_variant 0.28 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.33 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.32 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.33 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.33 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.35 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.35 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.29 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.25 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.24 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.24 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 0.21 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.17 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.22 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.22 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.23 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.23 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.31 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.34 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.38 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.37 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.27 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.19 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.42 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.24 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.41 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.44 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.57 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.17 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473653 n.-5_2delTGTGTTTinsGTGTAA non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.62 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.54 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.17 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
fabG1 1673633 p.Ser65Asn missense_variant 0.18 ethionamide
isoniazid
fabG1 1673637 p.Asp66Glu missense_variant 0.19 ethionamide
isoniazid
fabG1 1673641 p.Val68Ile missense_variant 0.21 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.34 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.33 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.33 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.36 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.41 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.42 ethionamide
isoniazid
fabG1 1673710 p.Leu91Ile missense_variant 0.52 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.5 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.4 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.32 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.3 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.31 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.26 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.27 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.28 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.28 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.31 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.31 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.31 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.3 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 0.3 ethionamide
isoniazid
inhA 1674105 c.-97C>T upstream_gene_variant 0.3 ethionamide
isoniazid
inhA 1674114 c.-88T>A upstream_gene_variant 0.25 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.25 ethionamide
isoniazid
inhA 1674126 c.-76G>C upstream_gene_variant 0.24 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.22 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.24 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.25 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.43 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.51 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.49 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.49 ethionamide
isoniazid
inhA 1674738 c.537C>G synonymous_variant 0.39 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 0.34 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 0.32 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 0.33 ethionamide
isoniazid
inhA 1674753 c.552G>C synonymous_variant 0.34 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.35 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.36 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 0.33 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.24 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 0.21 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.18 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.19 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.23 ethionamide
isoniazid
inhA 1674864 c.663C>T synonymous_variant 0.34 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.28 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.31 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.34 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.34 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.32 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.31 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 0.23 ethionamide
isoniazid
inhA 1674965 c.765delT frameshift_variant 0.26 ethionamide
isoniazid
inhA 1674969 c.768_769insG frameshift_variant 0.29 ethionamide
isoniazid
rpsA 1833532 c.-10A>C upstream_gene_variant 0.28 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.45 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.51 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.56 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.51 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.48 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.35 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.32 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.32 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.35 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.55 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.54 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.56 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.54 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.56 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.58 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.55 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.48 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 0.49 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.53 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.56 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.54 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.46 pyrazinamide
rpsA 1834096 c.555G>T synonymous_variant 0.27 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.26 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.29 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.21 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.24 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.29 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.33 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.35 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.39 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.39 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.48 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.46 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.45 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.48 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.4 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.38 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.38 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.31 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.32 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.23 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.26 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.34 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.3 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.32 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.3 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.31 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.29 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917951 c.12T>C synonymous_variant 0.19 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.27 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.29 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.31 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.32 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 0.28 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.27 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.2 capreomycin
bacA 2064972 c.-244T>C upstream_gene_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.32 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.32 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.33 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.34 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101765 c.1278C>G synonymous_variant 0.18 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>A synonymous_variant 0.18 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>G synonymous_variant 0.18 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101774 c.1269T>C synonymous_variant 0.17 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.18 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 0.21 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.24 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 0.2 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 0.2 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>A synonymous_variant 0.16 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>T synonymous_variant 0.2 ethionamide
delamanid
isoniazid
ndh 2102230 c.813G>C synonymous_variant 0.21 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.25 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102302 c.741G>C synonymous_variant 0.19 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 0.18 ethionamide
delamanid
isoniazid
ndh 2102623 c.420C>G synonymous_variant 0.23 ethionamide
delamanid
isoniazid
ndh 2102635 c.408C>G synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102638 c.405A>C synonymous_variant 0.34 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>G synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 0.26 ethionamide
delamanid
isoniazid
ndh 2102695 c.348C>T synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>T synonymous_variant 0.2 ethionamide
delamanid
isoniazid
katG 2155668 c.444G>T synonymous_variant 0.18 isoniazid
katG 2155677 c.435C>A synonymous_variant 0.2 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.19 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.19 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.21 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.25 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.21 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.22 isoniazid
katG 2155782 c.330C>G synonymous_variant 0.23 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.25 isoniazid
katG 2155794 p.Ala106Ser missense_variant 0.21 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
pncA 2289925 c.-684T>C upstream_gene_variant 0.48 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.48 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.48 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.46 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 0.46 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.44 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.39 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.35 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.37 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.37 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.31 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.27 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 0.21 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.18 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 0.18 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.19 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.49 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.48 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.27 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.26 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.17 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.24 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.32 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.33 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.27 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.21 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.2 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.22 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.23 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.26 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.28 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.3 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.3 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.34 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.35 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.33 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.33 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.4 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.29 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.27 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.28 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.28 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.28 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.32 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.33 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.47 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.44 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.42 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.35 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.4 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.4 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.33 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.29 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.53 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.45 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.41 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.4 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.39 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.38 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.44 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.28 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.2 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.18 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.25 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.25 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.31 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.33 isoniazid
kasA 2519108 c.994_996delGATinsCG frameshift_variant&missense_variant 0.33 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.38 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.41 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.46 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.38 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.32 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.32 isoniazid
ahpC 2726258 c.66C>T synonymous_variant 0.16 isoniazid Not assoc w R - Interim
ahpC 2726348 c.156T>C synonymous_variant 0.22 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.17 isoniazid Not assoc w R - Interim
ahpC 2726638 p.Ala149Val missense_variant 0.37 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.37 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.31 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.3 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.29 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.32 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.32 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.33 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.32 isoniazid
ahpC 2726717 c.525A>G synonymous_variant 0.25 isoniazid
folC 2746390 c.1209G>C synonymous_variant 0.18 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.18 para-aminosalicylic_acid
folC 2746399 c.1198_1200delTCCinsGG frameshift_variant&missense_variant 0.19 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.19 para-aminosalicylic_acid
folC 2746414 c.1183_1185delGAGinsCA frameshift_variant&missense_variant 0.26 para-aminosalicylic_acid
folC 2746420 c.1179A>G synonymous_variant 0.26 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.2 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.24 para-aminosalicylic_acid
folC 2747752 c.-154G>C upstream_gene_variant 0.16 para-aminosalicylic_acid
Rv2477c 2782432 c.1609_1611delGTGinsAC frameshift_variant&missense_variant 0.28 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782441 c.1602G>A synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782513 c.1530G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782841 p.Thr401Asn missense_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782852 c.1191T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 0.58 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783062 c.981C>T synonymous_variant 0.24 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.33 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.31 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.4 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.31 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.24 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.24 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783662 c.381G>A synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.26 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.17 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.19 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.52 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929