TB-Profiler result

Run: SRR7535086
Summary

Run ID: SRR7535086

Sample name:

Date: 2024-10-05T06:34:34.986725

Number of reads: 6633972

Percentage reads mapped: 48.55

Median coverage: 90.0

Strain:

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.15
lineage6.2.3 West-Africa 2 RD702 0.09
lineage4.6.1 Euro-American (Uganda) RD724 0.96
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.21 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.17 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.24 isoniazid
dnaA 33 c.33A>G synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 42 c.42C>T synonymous_variant 0.29 isoniazid
dnaA 51 c.51C>T synonymous_variant 0.16 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.2 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.2 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.19 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.19 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.19 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.19 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.18 isoniazid
dnaA 915 c.915C>T synonymous_variant 0.17 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.17 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.31 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.28 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.29 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.26 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.23 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.24 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.24 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.24 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.17 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.2 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.2 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.22 isoniazid
dnaA 1218 c.1218C>G synonymous_variant 0.24 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.22 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.26 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.28 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.31 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.35 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.31 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.21 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.2 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.21 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.34 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.33 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.29 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.26 isoniazid
gyrB 6100 c.861G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.27 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.2 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.27 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.33 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 6862 c.1623C>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.3 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>A upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 7126 c.1887G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7132 c.-170T>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7228 c.-74C>T upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7246 c.2007T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7347 p.Glu16Gln missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7539 p.Thr80Ala missense_variant 0.61 levofloxacin Not assoc w R
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7562 c.261C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 7571 c.270G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7697 c.396C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCTC synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7725 c.424C>T synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 7739 c.438C>T synonymous_variant 0.37 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7763 c.462T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8096 c.795T>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8106 c.805C>T synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8111 c.810G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8417 c.1116C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>A synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>A synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8780 p.Asp493Glu missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.43 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>A synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.36 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Glu missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9317 c.2016G>T synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13717 c.-159T>C upstream_gene_variant 0.18 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.18 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.2 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.22 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.27 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.26 isoniazid
fgd1 490782 c.-1G>C upstream_gene_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 490797 c.15G>A synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>C synonymous_variant 0.29 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 490827 c.45C>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 490848 c.66A>G synonymous_variant 0.42 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fgd1 490868 p.Ala29Gly missense_variant 0.39 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>A synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 490890 c.108C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 490896 c.114C>T synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>G synonymous_variant 0.15 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Asp missense_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>A synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491173 c.391C>A synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491302 p.Ile174Val missense_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491307 c.525C>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491313 c.531C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 491319 c.537G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491325 c.543G>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491337 c.555C>G synonymous_variant 0.36 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491526 c.744T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491535 c.753G>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491553 c.771G>A synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.41 pretomanid
delamanid
clofazimine
fgd1 491643 c.861G>A synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491646 c.864G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491661 c.879C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
mshA 575536 c.189T>C synonymous_variant 0.19 isoniazid
ethionamide
mshA 575542 c.195C>G synonymous_variant 0.17 isoniazid
ethionamide
mshA 575576 c.229C>T synonymous_variant 0.18 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.17 isoniazid
ethionamide
mshA 575649 p.Val101Ala missense_variant 0.18 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.22 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 0.22 isoniazid
ethionamide
mshA 575674 c.327G>C synonymous_variant 0.3 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.27 isoniazid Not assoc w R - Interim
ethionamide
mshA 575701 c.354G>A synonymous_variant 0.23 isoniazid
ethionamide
mshA 575704 c.357T>G synonymous_variant 0.25 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.24 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.3 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.33 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.36 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.33 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.31 isoniazid
ethionamide
mshA 575752 c.405G>C synonymous_variant 0.31 isoniazid
ethionamide
mshA 575755 c.408G>A synonymous_variant 0.32 isoniazid
ethionamide
mshA 575756 c.409C>T synonymous_variant 0.33 isoniazid
ethionamide
mshA 575770 c.423G>A synonymous_variant 0.3 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.3 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.29 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.25 isoniazid
ethionamide
mshA 575812 c.465C>T synonymous_variant 0.3 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.32 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.33 isoniazid
ethionamide
mshA 575830 c.483C>G synonymous_variant 0.33 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.38 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.36 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.35 isoniazid
ethionamide
mshA 575887 c.540G>C synonymous_variant 0.3 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.31 isoniazid
ethionamide
mshA 575896 c.549G>C synonymous_variant 0.29 isoniazid
ethionamide
mshA 575908 c.561A>G synonymous_variant 0.23 isoniazid
ethionamide
ccsA 619574 c.-317G>A upstream_gene_variant 0.16 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 619584 c.-307A>T upstream_gene_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 619609 c.-282G>C upstream_gene_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>A upstream_gene_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 619645 c.-246G>C upstream_gene_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>T upstream_gene_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.21 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.34 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.39 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 0.34 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>G synonymous_variant 0.22 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620682 c.792G>A synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620688 c.798G>C synonymous_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620763 c.873G>A synonymous_variant 0.29 kanamycin
capreomycin
amikacin
Rv0565c 656052 c.1419A>C synonymous_variant 0.2 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.17 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.27 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.23 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.19 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.2 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.28 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.3 ethionamide
Rv0565c 656448 p.Ile341Val missense_variant 0.33 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.33 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.33 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.34 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.35 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.3 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.26 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.25 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.24 ethionamide
Rv0565c 657220 p.Ala84Val missense_variant 0.16 ethionamide
Rv0565c 657231 p.Ile80Val missense_variant 0.24 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.3 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.36 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.37 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.37 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.35 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.53 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.43 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.37 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.37 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.32 ethionamide Uncertain significance
Rv0565c 657340 p.Ala44Glu missense_variant 0.28 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.29 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.29 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.29 ethionamide
Rv0565c 657354 p.Ile39Val missense_variant 0.29 ethionamide
Rv0565c 657363 c.108C>G synonymous_variant 0.28 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.23 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 0.37 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.37 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.33 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.31 ethionamide
Rv0565c 657670 c.-200A>T upstream_gene_variant 0.24 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.24 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.22 ethionamide
Rv0565c 657686 c.-216C>T upstream_gene_variant 0.22 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.21 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.21 ethionamide
hadA 731732 c.-198G>A upstream_gene_variant 0.2 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.27 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.34 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.33 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.33 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.35 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.31 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.21 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.19 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.17 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.2 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.23 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.26 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.26 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.26 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.5 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.53 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.53 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.53 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.55 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.56 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.47 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.43 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.43 isoniazid
nusG 734407 p.Val52Ile missense_variant 0.29 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.33 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.34 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.36 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.38 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.37 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.38 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.49 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.5 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.38 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.32 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.31 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.24 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.21 rifampicin
rpoB 759624 c.-183G>A upstream_gene_variant 0.17 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.25 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.31 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.36 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.43 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.33 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.35 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.42 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.43 rifampicin
rpoB 760343 c.537G>C synonymous_variant 0.45 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.45 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.45 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.53 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.49 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 0.45 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.41 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.41 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.42 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.49 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.55 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.44 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.38 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.38 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.38 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.29 rifampicin
rpoB 760781 c.975G>C synonymous_variant 0.25 rifampicin
rpoB 760869 p.Val355Ile missense_variant 0.23 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.31 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.37 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.36 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.49 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 0.55 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.5 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.5 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.53 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.43 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 0.47 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.58 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.35 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.35 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.28 rifampicin
rpoB 761373 p.Val523His missense_variant 0.28 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.3 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.32 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.3 rifampicin
rpoB 761439 p.Asp545Ser missense_variant 0.3 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.3 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.29 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.29 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.33 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.37 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.38 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.32 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.34 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.35 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.38 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.26 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761791 p.Arg662His missense_variant 0.18 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.27 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.27 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.29 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 0.29 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.33 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.33 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.36 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.37 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.34 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.29 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.29 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.3 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.32 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.31 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.47 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.27 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.27 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.2 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.2 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.21 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 0.46 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.52 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.52 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.5 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.26 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.26 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.2 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.21 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 0.16 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 0.18 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.28 rifampicin
rpoC 762446 c.-924C>G upstream_gene_variant 0.35 rifampicin
rpoB 762486 p.Pro894Ala missense_variant 0.2 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.19 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.22 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.22 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.42 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.39 rifampicin Not assoc w R
rpoC 763034 c.-336C>A upstream_gene_variant 0.39 rifampicin
rpoB 763040 c.3234C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.36 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 0.38 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.35 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.35 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.25 rifampicin
rpoB 763272 c.3466C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.5 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.52 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>G synonymous_variant 0.55 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763622 p.Ala85Ser missense_variant 0.16 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 0.35 rifampicin
rpoC 763642 c.273G>T synonymous_variant 0.14 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.55 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.46 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.51 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.53 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.52 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 0.57 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.6 rifampicin
rpoC 763780 c.411C>G synonymous_variant 0.58 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.55 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.53 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.49 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.45 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.45 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.45 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.43 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.44 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.44 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.42 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.42 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.43 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.46 rifampicin
rpoC 763951 c.582G>T synonymous_variant 0.5 rifampicin
rpoC 763960 c.591T>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763991 p.Ile208Leu missense_variant 0.46 rifampicin
rpoC 763996 c.627T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764005 c.636G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.44 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.41 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.4 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.43 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.42 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.42 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.42 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 0.44 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.4 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.46 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.52 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.51 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.51 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.52 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 0.52 rifampicin
rpoC 764293 c.924G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>G synonymous_variant 0.47 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.38 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.44 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.28 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.28 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.28 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.39 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.46 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.52 rifampicin
rpoC 764585 c.1216_1218delCTCinsTTG synonymous_variant 0.55 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.5 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>G synonymous_variant 0.41 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.36 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764815 c.1446A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.48 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.38 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.44 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.22 rifampicin Not assoc w R
rpoC 765383 p.Met672Leu missense_variant 0.2 rifampicin Uncertain significance
rpoC 765394 c.2025G>A synonymous_variant 0.27 rifampicin
rpoC 765404 p.Leu679Val missense_variant 0.29 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.31 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.31 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.44 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.39 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.41 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.39 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.39 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 0.38 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.37 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.44 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.41 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.39 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.42 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.43 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.2 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.25 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.21 rifampicin
rpoC 766061 p.Val898Leu missense_variant 0.3 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 0.32 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.31 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.29 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.24 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766168 c.2799C>G synonymous_variant 0.19 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.19 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857T>C synonymous_variant 0.19 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.17 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.18 rifampicin
rpoC 766279 c.2910C>G synonymous_variant 0.19 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.21 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 0.43 rifampicin
rpoC 766312 c.2943T>G synonymous_variant 0.43 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.42 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.39 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.48 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.46 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.43 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.38 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.36 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 0.36 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.33 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.38 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.37 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.34 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 0.39 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.35 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.35 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.26 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.25 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.25 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.24 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.33 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.38 rifampicin
rpoC 766633 c.3264G>C synonymous_variant 0.39 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.5 rifampicin
rpoC 766651 c.3282T>G synonymous_variant 0.48 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.46 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.4 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.44 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.41 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.41 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.35 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.37 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.4 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.55 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.53 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.51 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.54 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.52 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.56 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767035 c.3666G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.61 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.5 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 0.49 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.33 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.34 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.3 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.29 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.29 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776672 c.1809G>C synonymous_variant 0.2 bedaquiline
clofazimine
mmpL5 776675 c.1806G>A synonymous_variant 0.16 bedaquiline
clofazimine
mmpL5 776684 c.1797G>A synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 776694 p.Val596Thr missense_variant 0.19 bedaquiline
clofazimine
mmpL5 776738 c.1743C>T synonymous_variant 0.23 bedaquiline
clofazimine
mmpL5 776741 c.1740C>G synonymous_variant 0.19 bedaquiline
clofazimine
mmpL5 776744 c.1735_1737delCGCinsAGA synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 777176 p.Glu435Asp missense_variant 0.18 bedaquiline
clofazimine
mmpL5 777191 c.1290C>G synonymous_variant 0.18 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 0.19 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.19 bedaquiline
clofazimine
mmpL5 777212 p.Ala423Thr missense_variant 0.2 bedaquiline
clofazimine
mmpL5 777215 c.1266C>G synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 777218 c.1263G>A synonymous_variant 0.21 bedaquiline
clofazimine
mmpL5 777251 c.1230C>G synonymous_variant 0.16 bedaquiline
clofazimine
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.21 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.2 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.2 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.29 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.29 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.38 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.41 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.43 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.41 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.4 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.37 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.38 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.42 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.41 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.41 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.42 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.44 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.48 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.49 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.42 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.43 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.41 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.37 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.36 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.33 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.37 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.35 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.3 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.29 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.29 streptomycin Uncertain significance
rplC 800618 c.-191T>C upstream_gene_variant 0.4 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.4 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.42 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.41 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.48 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.46 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.45 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.47 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.46 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.56 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.56 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.41 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.42 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.42 linezolid
rplC 800814 c.6A>G synonymous_variant 0.41 linezolid
rplC 800817 c.9A>T synonymous_variant 0.41 linezolid
rplC 800844 c.36T>C synonymous_variant 0.43 linezolid
rplC 800865 c.57A>G synonymous_variant 0.38 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.38 linezolid
rplC 800874 c.66A>G synonymous_variant 0.32 linezolid
rplC 800875 p.Val23Ile missense_variant 0.29 linezolid
rplC 800880 c.72A>G synonymous_variant 0.3 linezolid
rplC 800889 c.81C>G synonymous_variant 0.31 linezolid
rplC 800892 c.84G>C synonymous_variant 0.3 linezolid
rplC 800907 c.99C>G synonymous_variant 0.22 linezolid
rplC 800916 c.108A>G synonymous_variant 0.19 linezolid
rplC 801153 c.345G>C synonymous_variant 0.18 linezolid
rplC 801156 c.348T>A synonymous_variant 0.23 linezolid
rplC 801168 c.360C>G synonymous_variant 0.3 linezolid
rplC 801171 c.363A>G synonymous_variant 0.31 linezolid
rplC 801174 c.366T>C synonymous_variant 0.31 linezolid
rplC 801195 c.387G>C synonymous_variant 0.34 linezolid
rplC 801207 c.399C>T synonymous_variant 0.4 linezolid
rplC 801246 c.438C>T synonymous_variant 0.36 linezolid
rplC 801249 c.441T>C synonymous_variant 0.33 linezolid
rplC 801255 c.447C>T synonymous_variant 0.25 linezolid
rplC 801264 c.456C>T synonymous_variant 0.21 linezolid
rplC 801267 c.459A>T synonymous_variant 0.21 linezolid
rplC 801279 c.471G>C synonymous_variant 0.18 linezolid
rplC 801282 c.474G>C synonymous_variant 0.19 linezolid
rplC 801285 c.477G>C synonymous_variant 0.19 linezolid
rplC 801300 c.492C>G synonymous_variant 0.26 linezolid
rplC 801309 c.501C>G synonymous_variant 0.19 linezolid
rplC 801312 c.504G>C synonymous_variant 0.23 linezolid
rplC 801321 c.513C>T synonymous_variant 0.22 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.23 linezolid
rplC 801339 c.531T>C synonymous_variant 0.25 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.25 linezolid
rplC 801348 c.540T>G synonymous_variant 0.28 linezolid
rplC 801357 c.549T>C synonymous_variant 0.3 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.32 linezolid
rplC 801402 c.594T>C synonymous_variant 0.28 linezolid
rplC 801405 c.597T>C synonymous_variant 0.29 linezolid
rplC 801438 c.630T>C synonymous_variant 0.18 linezolid
rplC 801442 p.Ile212Val missense_variant 0.17 linezolid
fbiC 1303539 c.609G>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1303728 c.798G>A synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.27 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1303761 c.831T>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1303797 c.867A>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>T synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303944 c.1014G>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303953 p.Asp341Glu missense_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303956 c.1026A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1303971 c.1041T>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>A synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304004 c.1074A>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304097 c.1167G>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304132 p.Ala401Gly missense_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304161 p.Arg411Ser missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304187 c.1257T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304208 c.1278C>T synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304223 c.1293G>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304226 c.1296C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304227 p.Met433Leu missense_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiC 1304535 c.1605G>A synonymous_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304545 p.Val539Thr missense_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>T synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.57 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304907 c.1977C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
sigE 1365033 c.621G>A synonymous_variant 0.23 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.23 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.29 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.32 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.31 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.28 pyrazinamide
sigE 1365087 c.675A>C synonymous_variant 0.27 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.28 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 0.28 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.29 pyrazinamide
sigE 1365114 c.702G>A synonymous_variant 0.25 pyrazinamide
sigE 1365117 c.705A>C synonymous_variant 0.26 pyrazinamide
sigE 1365118 c.706C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
atpE 1460816 c.-229T>C upstream_gene_variant 0.28 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.33 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.32 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.33 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.33 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.35 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.35 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.29 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.25 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.24 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.24 bedaquiline
atpE 1460915 c.-130C>G upstream_gene_variant 0.21 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.17 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.22 bedaquiline
atpE 1461150 p.Ile36Val missense_variant 0.22 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.23 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.23 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.31 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.34 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.38 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.37 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.27 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.19 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.31 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.27 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.42 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.42 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.39 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.41 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.44 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.55 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.17 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473653 n.-5_2delTGTGTTTinsGTGTAA non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.62 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.54 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.17 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
inhA 1673633 c.-569G>A upstream_gene_variant 0.18 isoniazid
ethionamide
inhA 1673637 c.-565C>G upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673641 c.-561G>A upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673657 c.-545C>A upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.33 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.36 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 0.41 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.42 isoniazid
ethionamide
inhA 1673710 c.-492C>A upstream_gene_variant 0.52 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 0.5 isoniazid
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 0.4 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.32 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673758 c.-444A>G upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673901 c.-301A>G upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1673916 c.-286A>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.31 isoniazid
ethionamide
inhA 1673961 c.-241A>C upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673985 c.-217C>G upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1674105 c.-97C>T upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1674114 c.-88T>A upstream_gene_variant 0.25 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.25 isoniazid
ethionamide
inhA 1674126 c.-76G>C upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1674136 c.-66T>G upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1674141 c.-61T>C upstream_gene_variant 0.25 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.43 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.54 isoniazid
ethionamide
inhA 1674672 c.471C>G synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.51 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674738 c.537C>G synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674741 c.540C>T synonymous_variant 0.34 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674746 p.Tyr182Phe missense_variant 0.32 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 0.33 isoniazid
ethionamide
inhA 1674753 c.552G>C synonymous_variant 0.34 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.36 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.33 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.24 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.18 isoniazid
ethionamide
inhA 1674828 c.627G>A synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.23 isoniazid
ethionamide
inhA 1674864 c.663C>T synonymous_variant 0.34 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.28 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.34 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.34 isoniazid
ethionamide
inhA 1674909 c.708G>A synonymous_variant 0.32 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674960 c.759C>G synonymous_variant 0.23 isoniazid
ethionamide
inhA 1674965 c.765delT frameshift_variant 0.26 isoniazid
ethionamide
inhA 1674969 c.768_769insG frameshift_variant 0.29 isoniazid
ethionamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.28 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.45 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.51 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.56 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.51 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.48 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.35 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.32 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.32 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.35 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.55 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.54 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.56 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.54 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.56 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.56 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.58 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.55 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.48 pyrazinamide
rpsA 1833877 c.336C>T synonymous_variant 0.49 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.53 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.56 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.54 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.46 pyrazinamide
rpsA 1834096 c.555G>T synonymous_variant 0.27 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.26 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.29 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.21 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.24 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.29 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.33 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.35 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.39 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.39 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.48 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.46 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.45 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.48 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.4 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.38 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.38 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.31 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.32 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.23 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.26 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.34 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.3 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.32 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.3 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.31 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.29 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917951 c.12T>C synonymous_variant 0.19 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.27 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.29 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.31 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.32 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 0.28 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.27 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.2 capreomycin
bacA 2064972 c.-244T>C upstream_gene_variant 0.36 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.33 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.34 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101765 c.1278C>G synonymous_variant 0.18 isoniazid
delamanid
ethionamide
ndh 2101768 c.1275C>A synonymous_variant 0.18 isoniazid
delamanid
ethionamide
ndh 2101771 c.1272T>G synonymous_variant 0.18 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2101774 c.1269T>C synonymous_variant 0.17 isoniazid
delamanid
ethionamide
ndh 2101777 c.1266C>G synonymous_variant 0.18 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 0.21 isoniazid
delamanid
ethionamide
ndh 2101804 c.1239T>G synonymous_variant 0.24 isoniazid
delamanid
ethionamide
ndh 2101808 p.Thr412Ser missense_variant 0.2 isoniazid
delamanid
ethionamide
ndh 2101830 p.Ile405Val missense_variant 0.2 isoniazid
delamanid
ethionamide
ndh 2102218 c.825C>A synonymous_variant 0.16 isoniazid
delamanid
ethionamide
ndh 2102227 c.816C>T synonymous_variant 0.2 isoniazid
delamanid
ethionamide
ndh 2102230 c.813G>C synonymous_variant 0.21 isoniazid
delamanid
ethionamide
ndh 2102233 c.810G>A synonymous_variant 0.25 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102302 c.741G>C synonymous_variant 0.19 isoniazid
delamanid
ethionamide
ndh 2102305 c.738T>C synonymous_variant 0.18 isoniazid
delamanid
ethionamide
ndh 2102623 c.420C>G synonymous_variant 0.23 isoniazid
delamanid
ethionamide
ndh 2102635 c.408C>G synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102638 c.405A>C synonymous_variant 0.34 isoniazid
delamanid
ethionamide
ndh 2102644 c.399A>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>G synonymous_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2102680 c.363T>G synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102683 c.360T>C synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2102695 c.348C>T synonymous_variant 0.25 isoniazid
delamanid
ethionamide
ndh 2102700 c.343C>T synonymous_variant 0.25 isoniazid
delamanid
ethionamide
ndh 2102710 c.333C>T synonymous_variant 0.2 isoniazid
delamanid
ethionamide
katG 2155668 c.444G>T synonymous_variant 0.18 isoniazid
katG 2155677 c.435C>A synonymous_variant 0.2 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.19 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.19 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.21 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.25 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.21 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.22 isoniazid
katG 2155782 c.330C>G synonymous_variant 0.23 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.25 isoniazid
katG 2155794 p.Ala106Ser missense_variant 0.21 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
pncA 2289925 c.-684T>C upstream_gene_variant 0.48 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.48 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.48 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.46 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 0.46 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.44 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.39 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.35 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.37 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.37 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.31 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.27 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCAC upstream_gene_variant 0.21 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.18 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 0.18 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.19 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.49 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.48 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.27 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.26 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.17 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.24 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.32 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.33 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.27 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.21 isoniazid
kasA 2518447 c.333T>G synonymous_variant 0.2 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.22 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.23 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.26 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.28 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.3 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.3 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.34 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.35 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.33 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.33 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.4 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.29 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.27 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.28 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.28 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.28 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.32 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.33 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.47 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.44 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.42 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.35 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.4 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.4 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.33 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.29 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.53 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.45 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.41 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.4 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.39 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.38 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.44 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.28 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.2 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.18 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.25 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.25 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.31 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.33 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 0.33 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.38 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.41 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.46 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.38 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.32 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.32 isoniazid
ahpC 2726258 c.66C>T synonymous_variant 0.16 isoniazid Not assoc w R - Interim
ahpC 2726348 c.156T>C synonymous_variant 0.22 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.17 isoniazid Not assoc w R - Interim
ahpC 2726638 p.Ala149Val missense_variant 0.37 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.37 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.31 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.3 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.29 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.32 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.32 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.33 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.32 isoniazid
ahpC 2726717 c.525A>G synonymous_variant 0.25 isoniazid
folC 2746390 c.1209G>C synonymous_variant 0.18 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.18 para-aminosalicylic_acid
folC 2746399 p.Ser400Ala missense_variant 0.19 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.19 para-aminosalicylic_acid
folC 2746414 p.Glu395Gln missense_variant 0.26 para-aminosalicylic_acid
folC 2746420 c.1179A>G synonymous_variant 0.26 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.2 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.24 para-aminosalicylic_acid
folC 2747752 c.-154G>C upstream_gene_variant 0.16 para-aminosalicylic_acid
Rv2477c 2782432 p.Val537Ile missense_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782513 c.1530G>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782841 p.Thr401Asn missense_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782852 c.1191T>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 0.58 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.23 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783062 c.981C>T synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.31 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.4 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.42 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.31 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783662 c.381G>A synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.17 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.52 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.54 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.54 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.52 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.53 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784051 c.-9C>A upstream_gene_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784052 c.-10A>C upstream_gene_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2681 2996876 c.138A>C synonymous_variant 1.0 capreomycin Not assoc w R
Rv2752c 3064838 c.1354T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065018 p.Asn392His missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065028 p.Val388Ile missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065040 c.1152C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065183 p.Ser337Ala missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065186 c.1006T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065190 p.Ile334Val missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065196 c.996T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065202 c.990T>G synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065205 c.987T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065210 c.982T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065223 c.969T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065229 c.963G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065232 c.960T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065241 c.951A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065262 c.930G>A synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065412 c.780G>A synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065418 c.774A>G synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065421 c.771G>A synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065442 c.750T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065451 c.741G>A synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065457 c.735A>C synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065463 c.729T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065915 c.277C>T synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065925 p.Ala89Gly missense_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065928 c.264G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065946 p.Gly82Ala missense_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066002 p.Met64Leu missense_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066009 c.183G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>G synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066074 c.118C>T synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066078 c.114C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066102 c.90C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066118 p.Asn25Ser missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066315 c.-124C>T upstream_gene_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066369 c.-180_-178delAGCinsGCG upstream_gene_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066396 c.-207_-205delGCGinsACC upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066399 c.-210_-208delATTinsTCC upstream_gene_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066582 c.-392_-391delCCinsGG upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067295 c.651C>T synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067376 c.570G>A synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.48 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.52 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.44 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.46 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.18 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067691 p.Ile85Leu missense_variant 0.27 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067736 p.Phe70Leu missense_variant 0.32 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.34 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.33 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067781 c.165C>A synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.35 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.3 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 0.19 para-aminosalicylic_acid
thyA 3073812 c.660C>G synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3073815 c.657G>A synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3073824 c.648A>G synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3073836 c.636C>T synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073872 p.Ile200Val missense_variant 0.39 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.41 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.19 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074163 p.Ala103Thr missense_variant 0.23 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.38 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3074241 c.231C>G synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074254 p.His73Arg missense_variant 0.26 para-aminosalicylic_acid
thyA 3074262 c.210T>C synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.24 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.24 para-aminosalicylic_acid
ald 3087278 p.Gln153His missense_variant 0.21 cycloserine
ald 3087281 c.462G>C synonymous_variant 0.22 cycloserine
ald 3087284 c.465C>G synonymous_variant 0.23 cycloserine
ald 3087290 c.471T>C synonymous_variant 0.28 cycloserine
ald 3087305 c.486G>C synonymous_variant 0.38 cycloserine
ald 3087311 c.492C>G synonymous_variant 0.41 cycloserine
ald 3087318 p.Glu167Lys missense_variant 0.41 cycloserine
ald 3087344 c.525C>G synonymous_variant 0.37 cycloserine
ald 3087347 c.528C>G synonymous_variant 0.34 cycloserine
ald 3087356 c.537C>G synonymous_variant 0.31 cycloserine
ald 3087368 c.549A>G synonymous_variant 0.27 cycloserine
ald 3087375 p.Ile186Val missense_variant 0.2 cycloserine
ald 3087380 c.561C>G synonymous_variant 0.18 cycloserine
whiB7 3569029 c.-350A>G upstream_gene_variant 1.0 kanamycin Not assoc w R
amikacin Uncertain significance
streptomycin Uncertain significance
lpqB 3623703 p.Ala403Val missense_variant 0.21 rifampicin
bedaquiline
lpqB 3623714 c.1197G>A synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3623721 p.Ser397Thr missense_variant 0.23 rifampicin
bedaquiline
lpqB 3623766 p.Gly382Ala missense_variant 0.25 rifampicin
bedaquiline
lpqB 3623774 c.1137C>T synonymous_variant 0.27 rifampicin
bedaquiline
lpqB 3623777 c.1134C>T synonymous_variant 0.27 rifampicin
bedaquiline
lpqB 3623782 p.Val377Ile missense_variant 0.26 rifampicin
bedaquiline
lpqB 3624077 c.834G>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624082 c.829A>C synonymous_variant 0.23 rifampicin
bedaquiline
lpqB 3624086 c.825C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624092 c.817_819delAGGinsCGC synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624100 c.811T>C synonymous_variant 0.19 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624116 c.795A>G synonymous_variant 0.21 rifampicin
bedaquiline
lpqB 3624119 c.792C>G synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624124 p.Leu263Val missense_variant 0.22 rifampicin
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3624143 c.768T>C synonymous_variant 0.28 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.42 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.36 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 0.29 rifampicin
bedaquiline
lpqB 3624770 c.141T>C synonymous_variant 0.26 rifampicin
bedaquiline
lpqB 3624776 c.135T>C synonymous_variant 0.21 rifampicin
bedaquiline
lpqB 3624783 p.Ser43Thr missense_variant 0.19 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 0.23 rifampicin
bedaquiline
lpqB 3625525 c.-615G>C upstream_gene_variant 0.25 rifampicin
bedaquiline
lpqB 3625528 c.-618G>T upstream_gene_variant 0.23 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.3 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.35 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.41 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.37 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 0.31 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625636 c.978C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.31 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.2 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625749 c.-839C>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.36 rifampicin Uncertain significance
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.39 rifampicin Uncertain significance
bedaquiline Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625849 c.-939T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3625876 c.738G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625909 c.-999T>G upstream_gene_variant 0.18 rifampicin
bedaquiline
mtrB 3626092 c.522T>C synonymous_variant 0.18 rifampicin
bedaquiline
mtrB 3626155 p.Ala153Ser missense_variant 0.26 rifampicin
bedaquiline
mtrB 3626158 c.456C>T synonymous_variant 0.26 rifampicin
bedaquiline
mtrB 3626170 c.444T>C synonymous_variant 0.22 rifampicin
bedaquiline
mtrB 3626179 c.435A>T synonymous_variant 0.18 rifampicin
bedaquiline
mtrB 3626687 c.-74G>T upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626900 c.-287G>A upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3627065 c.-452G>C upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627071 c.279G>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627074 c.-461G>C upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.49 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrA 3627146 c.204C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.49 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.51 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.35 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrA 3627917 c.-568G>C upstream_gene_variant 0.24 rifampicin
bedaquiline
mtrA 3627920 c.-571A>G upstream_gene_variant 0.24 rifampicin
bedaquiline
fbiB 3640866 c.-669T>C upstream_gene_variant 0.28 pretomanid
delamanid
clofazimine
fbiA 3640871 p.Ala110Gly missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3640878 c.-657T>C upstream_gene_variant 0.26 pretomanid
delamanid
clofazimine
fbiB 3640899 c.-636G>C upstream_gene_variant 0.2 pretomanid
delamanid
clofazimine
fbiA 3640900 p.Gln120Asn missense_variant 0.18 pretomanid
delamanid
clofazimine
fbiB 3642113 c.579A>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiB 3642114 p.Val194Ile missense_variant 0.21 pretomanid
delamanid
clofazimine Uncertain significance
fbiB 3642593 c.1059G>T synonymous_variant 0.16 pretomanid
delamanid
clofazimine
fbiB 3642609 p.Ser359Cys missense_variant 0.16 pretomanid
delamanid
clofazimine
fbiB 3642617 c.1083C>G synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiB 3642620 c.1086T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiB 3642656 c.1122G>C synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiB 3642719 c.1185T>C synonymous_variant 0.16 pretomanid
delamanid
clofazimine
rpoA 3877494 p.Glu338Asp missense_variant 0.23 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.25 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.27 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.31 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.43 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.43 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.46 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.45 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.43 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.41 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.28 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.23 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.22 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.28 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.27 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.24 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.27 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.26 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.25 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.23 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.38 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.49 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 0.47 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.41 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.35 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.31 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>C synonymous_variant 0.27 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.23 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.2 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.21 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.18 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.19 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.2 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.17 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.3 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.36 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.44 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.35 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.3 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.24 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.29 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.32 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.31 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.43 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.49 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.49 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.5 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.47 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.55 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.57 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.5 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.49 rifampicin
rpoA 3878463 c.45C>A synonymous_variant 0.47 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.39 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.3 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.31 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.32 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.32 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.23 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.2 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.21 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.21 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.21 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.23 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.24 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.39 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.47 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.51 rifampicin Uncertain significance
rpoA 3878806 c.-299C>A upstream_gene_variant 0.45 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.44 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.48 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.44 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.4 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.48 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoA 3878890 c.-383C>G upstream_gene_variant 0.47 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 0.43 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.45 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.44 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoA 3878932 c.-425G>A upstream_gene_variant 0.5 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.52 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.45 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.52 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.45 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.46 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.49 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.47 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.54 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.52 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.56 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.54 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.59 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.58 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.55 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.55 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.55 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.5 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.2 pretomanid
delamanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.21 pretomanid
delamanid
ddn 3986646 c.-198_-196delCTCinsTTG upstream_gene_variant 0.21 pretomanid
delamanid
clpC1 4038293 c.2412G>C synonymous_variant 0.2 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.21 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.18 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 0.19 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.19 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.19 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.26 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.31 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.3 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.26 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.31 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.32 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.28 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.26 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.19 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.2 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.3 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.34 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.38 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.38 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.38 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.37 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.4 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.35 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.3 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.3 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.32 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.28 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.29 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.28 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.3 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.32 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.28 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.29 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.29 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.3 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.29 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.37 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.39 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.43 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.46 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.41 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.56 pyrazinamide
clpC1 4038857 c.1848C>T synonymous_variant 0.69 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.62 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.48 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.42 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.38 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.38 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.36 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.33 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.42 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.54 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.52 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.48 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.49 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.5 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.28 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.17 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.19 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.29 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.39 pyrazinamide
clpC1 4039480 c.1225C>A synonymous_variant 0.37 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 0.34 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.33 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.31 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.52 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.43 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.32 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.25 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.18 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039805 c.900C>T synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.19 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.3 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.45 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.33 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.43 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.47 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.5 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.41 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.37 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.37 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.26 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.18 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.29 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.31 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.31 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.4 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.45 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.45 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.37 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.29 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.21 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.18 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.19 pyrazinamide
clpC1 4040492 c.213G>A synonymous_variant 0.27 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.2 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.2 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.32 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.31 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 0.25 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.25 pyrazinamide
clpC1 4040706 c.-4_-3delAC upstream_gene_variant 0.22 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.2 pyrazinamide
panD 4043882 p.Pro134Ser missense_variant 0.93 pyrazinamide Uncertain significance
panD 4044725 c.-444C>T upstream_gene_variant 0.22 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.22 pyrazinamide
panD 4044746 c.-467_-465delGTGinsATC upstream_gene_variant 0.26 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.29 pyrazinamide
panD 4044758 c.-477C>T upstream_gene_variant 0.33 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.39 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.43 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.44 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.44 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.4 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.4 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.41 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.37 pyrazinamide
panD 4044848 c.-567T>A upstream_gene_variant 0.37 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.35 pyrazinamide
panD 4044860 c.-579C>G upstream_gene_variant 0.29 pyrazinamide
panD 4044872 c.-591C>G upstream_gene_variant 0.17 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.2 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 0.23 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.23 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.21 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.19 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.32 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.35 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.4 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.35 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.28 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.24 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.24 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.24 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.19 pyrazinamide
glpK 4138472 c.1284G>T synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138565 c.1191G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>A synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138654 c.1102C>T synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138679 p.Met359Val missense_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138695 p.Pro354Asp missense_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138763 c.993G>A synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139126 c.630G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139132 c.624A>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139135 p.Asp207Asn missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139143 c.613T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139165 c.591A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139168 c.588T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139177 c.579T>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.573T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139186 c.570G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139195 c.561G>T synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139198 c.558C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139207 c.549T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139217 p.Val180Ala missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139231 c.525A>C synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139537 c.219G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139541 p.Ile72Thr missense_variant 0.22 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139545 c.211T>C synonymous_variant 0.21 levofloxacin
moxifloxacin Not assoc w R - Interim
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139552 p.Ala68Ser missense_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139581 p.Asn59Asp missense_variant 0.37 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139597 c.159C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139601 p.Arg52Gln missense_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139615 c.141G>A synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
glpK 4139651 p.His35Glu missense_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139670 p.Cys29Tyr missense_variant 0.6 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
isoniazid Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4139675 c.81C>G synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139684 c.72C>G synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139687 c.69C>G synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4239157 c.-706C>T upstream_gene_variant 0.18 ethambutol
embC 4239161 c.-702A>T upstream_gene_variant 0.2 ethambutol
embC 4239165 c.-698C>T upstream_gene_variant 0.2 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 0.22 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.23 ethambutol
embC 4239209 c.-654G>C upstream_gene_variant 0.19 ethambutol
embC 4239336 c.-527_-525delTTGinsCTA upstream_gene_variant 0.27 ethambutol
embC 4239341 c.-522G>C upstream_gene_variant 0.26 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.26 ethambutol
embC 4239350 c.-513G>C upstream_gene_variant 0.33 ethambutol
embC 4239378 c.-485T>A upstream_gene_variant 0.33 ethambutol
embC 4239383 c.-480C>G upstream_gene_variant 0.32 ethambutol
embC 4239401 c.-462A>G upstream_gene_variant 0.34 ethambutol
embC 4240654 c.792C>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embC 4240660 c.798C>G synonymous_variant 0.18 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.17 ethambutol Not assoc w R
embC 4240685 p.Thr275Ala missense_variant 0.26 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.24 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.46 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.47 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.47 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.43 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.36 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.31 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.29 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.26 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.24 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.25 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.23 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.21 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.19 ethambutol Not assoc w R
embC 4241002 c.1140G>C synonymous_variant 0.18 ethambutol
embC 4241013 p.Met384Thr missense_variant 0.19 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.18 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.29 ethambutol
embC 4241032 c.1170G>C synonymous_variant 0.4 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.46 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.49 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.49 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.55 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.53 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.53 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.51 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.34 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.28 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.26 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.31 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.28 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.23 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embC 4241218 c.1356G>C synonymous_variant 0.19 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.4 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.41 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.24 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.24 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.25 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.26 ethambutol
embC 4241500 c.1638A>C synonymous_variant 0.22 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.22 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.23 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.2 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embC 4241727 p.Phe622Tyr missense_variant 0.23 ethambutol
embC 4241741 p.Val627Leu missense_variant 0.27 ethambutol
embC 4241747 p.Val629Leu missense_variant 0.27 ethambutol
embC 4241750 p.Leu630Val missense_variant 0.26 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.22 ethambutol
embC 4241770 c.1908T>C synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embC 4241794 c.1932C>G synonymous_variant 0.17 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.18 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242710 p.Gln950Glu missense_variant 0.27 ethambutol
embC 4242715 c.2853T>C synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embA 4242742 c.-491C>G upstream_gene_variant 0.34 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.3 ethambutol
embA 4242754 c.-479G>C upstream_gene_variant 0.29 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.26 ethambutol
embA 4242772 c.-461G>C upstream_gene_variant 0.26 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.23 ethambutol
embC 4242841 c.2979C>T synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embA 4242847 c.-386C>A upstream_gene_variant 0.19 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.2 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.2 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.21 ethambutol
embC 4242883 c.3021C>G synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embA 4242892 c.-341G>C upstream_gene_variant 0.26 ethambutol
embA 4242901 c.-332G>C upstream_gene_variant 0.23 ethambutol
embA 4244516 c.1284G>C synonymous_variant 0.27 ethambutol
embA 4244517 p.Leu429Val missense_variant 0.26 ethambutol
embA 4244523 p.Pro431Ala missense_variant 0.31 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.3 ethambutol
embA 4244537 c.1305T>G synonymous_variant 0.31 ethambutol
embA 4244543 c.1311C>G synonymous_variant 0.31 ethambutol
embA 4244547 p.Ile439Val missense_variant 0.3 ethambutol
embA 4244557 p.Arg442Thr missense_variant 0.33 ethambutol
embA 4244582 c.1350T>C synonymous_variant 0.43 ethambutol
embA 4244585 c.1353A>G synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embA 4244611 p.Ala460Gly missense_variant 0.21 ethambutol
embA 4245053 c.1821G>C synonymous_variant 0.17 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.21 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.29 ethambutol
embA 4245089 c.1857G>C synonymous_variant 0.36 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.43 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.53 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.58 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.57 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.56 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.64 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.63 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.61 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.58 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.55 ethambutol
embA 4245222 p.Tyr664Gln missense_variant 0.48 ethambutol
embA 4245248 c.2016G>C synonymous_variant 0.38 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.33 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embA 4245693 p.Ile821Val missense_variant 0.3 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.32 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.35 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.43 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.43 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.45 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.44 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.38 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.32 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embA 4246235 c.3003G>A synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.26 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.3 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.32 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.33 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.36 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.44 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.48 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.48 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.45 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.47 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.46 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.4 ethambutol
embA 4246359 p.Ala1043Ser missense_variant 0.38 ethambutol
embB 4246367 c.-147C>T upstream_gene_variant 0.32 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.3 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.3 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4246400 c.-114G>C upstream_gene_variant 0.19 ethambutol
embB 4247059 c.546C>A synonymous_variant 0.18 ethambutol
embB 4247074 c.561G>T synonymous_variant 0.18 ethambutol
embB 4247095 c.582G>T synonymous_variant 0.18 ethambutol
embB 4247114 p.Ala201Thr missense_variant 0.17 ethambutol Uncertain significance
embB 4247119 c.606C>G synonymous_variant 0.18 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embB 4247446 c.933C>T synonymous_variant 0.18 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.3 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.32 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.38 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.35 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.43 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.4 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.32 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.26 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.2 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.18 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.17 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.17 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.19 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.18 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.17 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.17 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.18 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.21 ethambutol
embB 4247819 p.Val436Ile missense_variant 0.21 ethambutol Uncertain significance
embB 4247830 c.1317A>G synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.28 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.28 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.28 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.33 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.34 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.44 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.49 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.43 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.34 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.39 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.37 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.36 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.3 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.24 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.24 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.24 ethambutol Uncertain significance
embB 4248070 c.1557T>C synonymous_variant 0.38 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.35 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.34 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.35 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.33 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.33 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.33 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.33 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4248199 c.1686A>G synonymous_variant 0.31 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.31 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.31 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.33 ethambutol Uncertain significance
embB 4248220 c.1707A>C synonymous_variant 0.43 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.43 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.39 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.34 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.33 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.27 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.28 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.26 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.26 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.29 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.25 ethambutol
embB 4248407 p.Leu632Val missense_variant 0.19 ethambutol
embB 4248410 p.Phe633Leu missense_variant 0.19 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.19 ethambutol
embB 4248432 p.Trp640Leu missense_variant 0.16 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.22 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.23 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.23 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.24 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.28 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.29 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.29 ethambutol
embB 4249447 c.2934G>A synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embB 4249469 p.Leu986Met missense_variant 0.33 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.32 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.29 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.2 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.19 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.2 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.2 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.19 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.18 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.16 ethambutol
aftB 4267190 c.1647T>A synonymous_variant 0.18 ethambutol
aftB 4267200 p.Trp546Val missense_variant 0.21 ethambutol
aftB 4267214 c.1623A>C synonymous_variant 0.24 ethambutol
aftB 4267241 c.1596G>C synonymous_variant 0.2 ethambutol
aftB 4267244 c.1593T>C synonymous_variant 0.18 ethambutol
aftB 4267256 c.1581C>G synonymous_variant 0.18 ethambutol
aftB 4267262 c.1575T>C synonymous_variant 0.17 ethambutol
aftB 4267604 c.1233C>G synonymous_variant 0.23 ethambutol
aftB 4267607 c.1230G>A synonymous_variant 0.24 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.25 ethambutol
aftB 4267628 c.1209C>G synonymous_variant 0.22 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.22 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 0.17 ethambutol Not assoc w R - Interim
aftB 4268985 c.-149A>G upstream_gene_variant 0.19 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.24 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.24 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.25 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.31 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.33 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.33 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.33 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.33 ethambutol
ubiA 4269075 p.Ile253Val missense_variant 0.22 ethambutol
aftB 4269081 c.-245G>C upstream_gene_variant 0.19 ethambutol
aftB 4269084 c.-248G>C upstream_gene_variant 0.18 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.18 ethambutol
aftB 4269186 c.-350C>G upstream_gene_variant 0.18 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.22 ethambutol
aftB 4269206 c.-370C>T upstream_gene_variant 0.23 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.23 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
aftB 4269242 c.-406C>T upstream_gene_variant 0.26 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.26 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.22 ethambutol
aftB 4269258 c.-422C>T upstream_gene_variant 0.18 ethambutol
ethR 4327435 c.-114T>G upstream_gene_variant 0.16 ethionamide
ethR 4327438 c.-111A>G upstream_gene_variant 0.17 ethionamide
ethR 4327453 c.-96A>G upstream_gene_variant 0.17 ethionamide
ethR 4327459 c.-90G>A upstream_gene_variant 0.18 ethionamide
ethR 4327468 c.-81G>A upstream_gene_variant 0.19 ethionamide
ethA 4328329 c.-856C>G upstream_gene_variant 1.0 ethionamide
ethA 4328463 c.-990G>C upstream_gene_variant 0.28 ethionamide
ethA 4328467 c.-994G>T upstream_gene_variant 0.27 ethionamide
ethA 4328470 c.-998_-997delAGinsGC upstream_gene_variant 0.26 ethionamide
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin