TB-Profiler result

Run: ERR4769497
Summary

Run ID: ERR4769497

Sample name:

Date: 2024-10-04T19:06:20.571847

Number of reads: 299346

Percentage reads mapped: 8.35

Median coverage: 4.0

Strain: La1;lineage4.9

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.91
lineage4.9 Euro-American (H37Rv-like) None 0.84
La1 M.bovis None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Thr500Asn Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.2373_2374delTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2382_2383insAG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6738 p.Thr500Asn missense_variant 0.83 levofloxacin Uncertain significance Mutation from literature
moxifloxacin Uncertain significance Mutation from literature
fbiC 1305302 c.2373_2374delTG frameshift_variant 0.65 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305311 c.2382_2383insAG frameshift_variant 0.68 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance Mutation from literature
embB 4247580 p.Ala356Val missense_variant 0.6 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 534 c.534T>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 540 c.540C>T synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 541 p.Ala181Thr missense_variant 0.79 isoniazid
dnaA 552 c.552G>C synonymous_variant 0.86 isoniazid
dnaA 570 c.570C>G synonymous_variant 0.8 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.8 isoniazid
dnaA 576 c.576G>C synonymous_variant 0.8 isoniazid
dnaA 579 c.579C>T synonymous_variant 0.86 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>C synonymous_variant 0.92 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.93 isoniazid
dnaA 600 c.600T>C synonymous_variant 0.95 isoniazid
dnaA 624 c.624C>T synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 633 c.633T>G synonymous_variant 0.83 isoniazid
dnaA 636 c.636C>G synonymous_variant 0.83 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.75 isoniazid
dnaA 663 c.663A>C synonymous_variant 0.7 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
dnaA 673 p.Ala225Thr missense_variant 0.62 isoniazid Uncertain significance
dnaA 678 c.678A>G synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.62 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.65 isoniazid
dnaA 699 c.699G>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.62 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.62 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.65 isoniazid
dnaA 723 c.723A>G synonymous_variant 0.59 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.56 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>T synonymous_variant 0.46 isoniazid Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 6559 c.-743C>A upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6582 p.Thr448Asn missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6589 c.-713G>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 6604 c.-698G>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6674 c.-628_-626delCTTinsTTG upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7514 c.213C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8324 c.1023T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.8 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8429 c.1128C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>T synonymous_variant 0.91 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 8735 c.1434C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8740 p.Arg480His missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8769 p.His490Tyr missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8817 p.Ser506Ala missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9080 c.1779G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9144 p.Arg615Lys missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9147 p.Gly616Ser missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9212 c.1911G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9281 c.1980C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCGC synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491526 c.744T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491536 c.754C>T synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491553 c.771G>A synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
mshA 575714 p.Tyr123Asn missense_variant 0.7 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 0.82 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.85 isoniazid
ethionamide
mshA 575752 c.405G>C synonymous_variant 0.85 isoniazid
ethionamide
mshA 575770 c.423G>C synonymous_variant 0.79 isoniazid
ethionamide
mshA 575772 p.Val142Ala missense_variant 0.79 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.85 isoniazid
ethionamide
mshA 575780 p.Pro145Ala missense_variant 0.85 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.85 isoniazid
ethionamide
mshA 575788 c.441C>T synonymous_variant 0.85 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.85 isoniazid
ethionamide
mshA 575803 c.456C>T synonymous_variant 0.79 isoniazid Not assoc w R - Interim
ethionamide
ccsA 620547 c.657C>G synonymous_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620556 c.666C>G synonymous_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620569 p.Gly227Arg missense_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620583 c.693G>A synonymous_variant 0.72 kanamycin
capreomycin
amikacin
ccsA 620589 c.699G>C synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>G synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620634 c.744C>G synonymous_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620643 c.753C>G synonymous_variant 0.87 kanamycin
capreomycin
amikacin
ccsA 620648 p.Glu253Gly missense_variant 0.87 kanamycin
capreomycin
amikacin
ccsA 620688 c.798G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620691 c.801G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>A synonymous_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620712 c.822G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
nusG 734391 c.138C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
nusG 734407 p.Val52Ile missense_variant 0.56 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.56 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.58 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.62 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.68 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.68 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.75 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734505 c.252G>T synonymous_variant 0.92 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.87 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.87 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>T synonymous_variant 0.85 rifampicin
nusG 734589 c.336G>C synonymous_variant 0.83 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734596 c.343_345delTTGinsCTC synonymous_variant 0.82 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 0.82 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.83 rifampicin
rpoB 760148 p.Asp114Glu missense_variant 0.87 rifampicin
rpoB 760155 p.Lys117Arg missense_variant 0.87 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.88 rifampicin
rpoB 760178 c.372G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 0.89 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>G synonymous_variant 1.0 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.7 rifampicin
rpoB 760587 p.Thr261Ala missense_variant 0.7 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.7 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760628 c.822G>A synonymous_variant 0.73 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.8 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760674 c.868T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760682 c.876C>T synonymous_variant 0.73 rifampicin
rpoB 760683 c.877T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761003 c.1197C>G synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761012 c.1206C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.94 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 1.0 rifampicin
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761201 c.1395G>A synonymous_variant 1.0 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 1.0 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.96 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 0.95 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.93 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.91 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 1.0 rifampicin
rpoB 761508 p.Ser568Ala missense_variant 1.0 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761534 c.1728G>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.94 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.94 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.9 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.91 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.9 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.9 rifampicin
rpoB 761699 c.1893C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761705 c.1899C>G synonymous_variant 0.93 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.69 rifampicin
rpoB 761814 p.Ala670Asn missense_variant 0.69 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.75 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.65 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.65 rifampicin
rpoB 761859 p.Asp685Asn missense_variant 0.65 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761868 p.Asp688Gln missense_variant 0.61 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.61 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.63 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 0.58 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.63 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762006 c.2200_2202delCGCinsAGG synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762024 p.Val740Thr missense_variant 0.78 rifampicin Uncertain significance
rpoB 762029 c.2223C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.91 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.88 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.87 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.93 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.93 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.9 rifampicin
rpoB 762236 c.2430G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.94 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.9 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.94 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.94 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.94 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.94 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.91 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 0.9 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.92 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.92 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762443 c.-927G>C upstream_gene_variant 0.9 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 762491 c.-879T>G upstream_gene_variant 0.84 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.79 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.79 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 0.85 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.85 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.82 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.82 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.8 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.77 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.97 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.97 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 0.96 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoB 763203 p.Ser1133Ala missense_variant 1.0 rifampicin Uncertain significance
rpoB 763207 p.Ser1134Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763430 c.61A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.89 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763609 c.240C>T synonymous_variant 0.91 rifampicin
rpoC 763618 c.249C>T synonymous_variant 0.91 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.88 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.83 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.83 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.91 rifampicin
rpoC 763969 c.600C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 0.95 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 0.96 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.88 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Ile missense_variant 0.88 rifampicin
rpoC 764213 p.Arg282Lys missense_variant 0.84 rifampicin Uncertain significance
rpoC 764227 c.858G>C synonymous_variant 0.85 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.86 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.91 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.91 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.86 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.85 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.88 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.93 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.94 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.95 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.89 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.89 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.89 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.86 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.85 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.91 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764656 c.1287C>T synonymous_variant 0.9 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>C synonymous_variant 0.91 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>G synonymous_variant 0.92 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.88 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.88 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.87 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.87 rifampicin Uncertain significance
rpoC 764932 c.1563C>G synonymous_variant 0.88 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 0.9 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.93 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.96 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.95 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.95 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.95 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 0.73 rifampicin
rpoC 765382 c.2013G>C synonymous_variant 0.73 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.75 rifampicin Uncertain significance
rpoC 765402 c.2033_2034insT frameshift_variant 0.79 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 0.79 rifampicin Uncertain significance
rpoC 765408 c.2041delT frameshift_variant 0.79 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765422 p.Asn685Asp missense_variant 0.77 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765453 p.Ala695Val missense_variant 0.82 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765544 c.2175C>G synonymous_variant 0.8 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.8 rifampicin
rpoC 765553 c.2184C>G synonymous_variant 0.8 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.81 rifampicin
rpoC 765611 p.His748Ser missense_variant 0.71 rifampicin Uncertain significance
rpoC 765628 c.2259G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765635 p.Val756Leu missense_variant 0.7 rifampicin
rpoC 765640 c.2271A>G synonymous_variant 0.7 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765662 c.2293_2295delTTGinsCTC synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765669 p.His767Arg missense_variant 0.71 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765718 p.Asp783Glu missense_variant 0.84 rifampicin Uncertain significance
rpoC 765724 c.2355C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.93 rifampicin
rpoC 765742 p.Glu791Asp missense_variant 0.93 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 0.91 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 0.91 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765937 c.2568T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766297 c.2928G>C synonymous_variant 0.82 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.82 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.82 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766351 c.2982C>G synonymous_variant 0.81 rifampicin
rpoC 766357 c.2988C>T synonymous_variant 0.82 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.83 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.84 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.84 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.83 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766447 c.3078T>C synonymous_variant 0.82 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.81 rifampicin
rpoC 766462 c.3093G>T synonymous_variant 0.82 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 0.78 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.84 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.84 rifampicin
rpoC 766517 p.Thr1050Ala missense_variant 0.82 rifampicin
rpoC 766522 c.3153C>T synonymous_variant 0.81 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.8 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.79 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.79 rifampicin
rpoC 766564 c.3195C>G synonymous_variant 0.86 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 0.86 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766576 c.3207C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766582 c.3213C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.86 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.91 rifampicin
rpoC 766610 p.Ser1081Pro missense_variant 0.91 rifampicin
rpoC 766618 c.3249G>T synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 0.92 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.92 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.92 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.92 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.86 rifampicin
rpoC 766693 c.3324C>G synonymous_variant 0.92 rifampicin
rpoC 766702 c.3333G>C synonymous_variant 0.93 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 0.88 rifampicin
rpoC 766711 c.3342C>G synonymous_variant 0.86 rifampicin
rpoC 766714 c.3345G>T synonymous_variant 0.88 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.9 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.9 rifampicin
rpoC 766747 c.3378C>A synonymous_variant 0.85 rifampicin
rpoC 766753 c.3384C>T synonymous_variant 0.83 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.79 rifampicin
rpoC 766775 p.Arg1136Asn missense_variant 0.79 rifampicin
rpoC 766787 p.Glu1140Gln missense_variant 0.8 rifampicin Uncertain significance
rpoC 766798 c.3429C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766831 c.3462C>T synonymous_variant 0.83 rifampicin
rpoC 766843 c.3474T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.81 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.78 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.78 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.78 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.82 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.82 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.78 rifampicin
rpoC 766918 c.3549C>G synonymous_variant 0.78 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 0.78 rifampicin
rpoC 766931 p.Ala1188Thr missense_variant 0.79 rifampicin Uncertain significance
rpoC 766935 p.Glu1189Ala missense_variant 0.79 rifampicin
rpoC 766945 c.3576A>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766961 p.Gly1198Leu missense_variant 0.82 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767041 c.3672G>C synonymous_variant 0.89 rifampicin
rpoC 767044 c.3675G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 767110 c.3741T>C synonymous_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767182 c.3813G>C synonymous_variant 1.0 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 1.0 rifampicin
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>G synonymous_variant 0.94 rifampicin
rpoC 767212 c.3843G>T synonymous_variant 0.94 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767266 c.3897G>C synonymous_variant 0.91 rifampicin
rpsL 781652 c.93T>G synonymous_variant 0.62 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.62 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.67 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.81 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>G synonymous_variant 0.8 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.79 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.83 streptomycin
rpsL 781726 p.Lys56Arg missense_variant 0.83 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.83 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.83 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.83 streptomycin
rpsL 781742 c.183C>G synonymous_variant 0.83 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.83 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.83 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.84 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.85 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.85 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.87 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.93 streptomycin
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>G synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781853 c.294C>T synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.92 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.93 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.92 streptomycin Uncertain significance
rplC 800537 c.-272C>G upstream_gene_variant 0.7 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.64 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.64 linezolid
rplC 800564 c.-245C>T upstream_gene_variant 0.64 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.64 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.58 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.58 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.58 linezolid
rplC 800585 c.-223_-220delGCCA upstream_gene_variant 0.58 linezolid
rplC 800594 c.-215_-214insTGTA upstream_gene_variant 0.58 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 0.62 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.64 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.71 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.73 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.75 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.82 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.88 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.88 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.82 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.75 linezolid
fbiC 1303545 c.615A>G synonymous_variant 0.84 pretomanid
delamanid
clofazimine
fbiC 1303554 c.624G>T synonymous_variant 0.8 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303575 c.645G>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303581 c.651G>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303587 c.657G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>G synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303629 c.699C>T synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1303638 c.708A>G synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fbiC 1303641 c.711C>T synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303646 p.Ala239Val missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1303653 c.723G>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1303674 c.744C>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1303677 c.747C>A synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1303681 c.751T>C synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1303689 c.759T>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1305234 c.2304G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305237 c.2307A>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1305240 c.2310T>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305243 c.2313T>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305252 c.2322G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305267 c.2337C>T synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305274 p.Ser782Ala missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1305277 p.His783Asn missense_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1305297 c.2367G>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305300 c.2370A>G synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305306 c.2376A>G synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1305318 c.2388C>G synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Asn missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1305339 c.2409C>A synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1305360 c.2430G>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1305381 c.2451G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305390 c.2460C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305393 c.2463T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305399 c.2469A>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
sigE 1364898 c.486C>T synonymous_variant 0.75 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.8 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.75 pyrazinamide
sigE 1364920 p.Glu170Gln missense_variant 0.75 pyrazinamide
sigE 1364926 p.Asn172Asp missense_variant 0.75 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 0.8 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 0.85 pyrazinamide
sigE 1364960 p.Gly183Asp missense_variant 0.85 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>G synonymous_variant 0.85 pyrazinamide
sigE 1364979 c.567C>G synonymous_variant 0.85 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.85 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.85 pyrazinamide
sigE 1364992 p.Pro194Ala missense_variant 0.85 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 0.85 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.85 pyrazinamide
atpE 1461097 p.Ala18Gly missense_variant 0.64 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.62 bedaquiline
atpE 1461146 c.102G>C synonymous_variant 0.67 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.67 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 0.67 bedaquiline Uncertain significance
atpE 1461158 c.114T>A synonymous_variant 0.67 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.67 bedaquiline Uncertain significance
atpE 1461167 c.123G>C synonymous_variant 0.73 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.73 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 0.73 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.73 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.73 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.73 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.8 bedaquiline
atpE 1461215 c.171C>T synonymous_variant 0.8 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.8 bedaquiline
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.92 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.89 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472292 n.447A>G non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453G>C non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472302 n.457_458insT non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472310 n.465_466insG non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472431 n.586G>A non_coding_transcript_exon_variant 0.95 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838_839insTA non_coding_transcript_exon_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.97 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.95 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473111 n.1266A>T non_coding_transcript_exon_variant 0.95 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.84 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.79 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1473810 n.153C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474106 n.449A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474107 n.450T>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474108 n.451C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474109 n.452A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474110 n.453A>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474287 n.630_644delTCCTTTTCCTCTCCGinsCTCCCTT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696_699delACATinsGCAC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474708 n.1052dupG non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474711 n.1054_1055insA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474715 n.1061delA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475375 n.1718G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475378 n.1721A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475396 n.1739_1740insTG non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475400 n.1743C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid Uncertain significance
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475408 n.1752delT non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475433 n.1776A>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476108 n.2451T>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
inhA 1673901 c.-301A>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673904 c.-298C>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1674514 p.Ile105Val missense_variant 0.79 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.87 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 0.87 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.84 isoniazid
ethionamide
inhA 1674585 c.384T>G synonymous_variant 0.84 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 0.85 isoniazid
ethionamide
inhA 1674597 c.396G>A synonymous_variant 0.83 isoniazid
ethionamide
inhA 1674601 p.Leu134Val missense_variant 0.83 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674636 c.435C>G synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 0.85 isoniazid
ethionamide
rpsA 1833589 c.48A>C synonymous_variant 0.73 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.73 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.79 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.82 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.82 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.89 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.89 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.86 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.86 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.86 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.82 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.85 pyrazinamide
rpsA 1833770 p.Asn77His missense_variant 0.92 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.93 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.93 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.93 pyrazinamide
rpsA 1833806 c.265C>T synonymous_variant 0.93 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833814 c.273C>G synonymous_variant 0.89 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 0.93 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.89 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.89 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.89 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.93 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.91 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.86 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.9 pyrazinamide
rpsA 1833976 c.435C>G synonymous_variant 0.9 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.91 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.88 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834042 c.501G>A synonymous_variant 0.96 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.96 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.93 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.93 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.93 pyrazinamide Uncertain significance
rpsA 1834172 p.Ile211Val missense_variant 0.94 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.91 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.89 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.88 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834522 c.981C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834527 p.Arg329His missense_variant 0.94 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834573 c.1032G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834603 p.Glu354Asp missense_variant 0.88 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.84 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.88 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.88 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834751 p.Leu404Ile missense_variant 0.94 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.94 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.94 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.85 linezolid
tsnR 1853372 c.-234A>C upstream_gene_variant 0.83 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.79 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 0.81 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.78 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.84 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.76 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.76 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.8 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.79 linezolid
tsnR 1853441 c.-165C>T upstream_gene_variant 0.74 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.74 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.74 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.69 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.69 linezolid
kasA 2517926 c.-189G>A upstream_gene_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.85 isoniazid
kasA 2518564 c.450C>G synonymous_variant 0.8 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.8 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.81 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.76 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.76 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.76 isoniazid
kasA 2518594 c.480C>T synonymous_variant 0.76 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.75 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.75 isoniazid
kasA 2518618 c.504G>C synonymous_variant 0.82 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.8 isoniazid
kasA 2518630 c.516G>C synonymous_variant 0.8 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.8 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.82 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.8 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.73 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.73 isoniazid
kasA 2518681 c.567C>T synonymous_variant 0.73 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.73 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.77 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.69 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.82 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.82 isoniazid
kasA 2518727 c.613C>T synonymous_variant 0.86 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.87 isoniazid
kasA 2518738 c.624G>A synonymous_variant 0.87 isoniazid
kasA 2518739 p.Ala209Thr missense_variant 0.87 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.88 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.89 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.89 isoniazid
kasA 2518765 c.651G>C synonymous_variant 0.86 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.83 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.82 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.82 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.83 isoniazid
kasA 2518816 c.702C>G synonymous_variant 0.8 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.8 isoniazid
kasA 2518834 c.720C>T synonymous_variant 0.79 isoniazid
kasA 2518837 c.723G>A synonymous_variant 0.78 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.78 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.72 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.69 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.69 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.69 isoniazid
kasA 2518882 c.768C>A synonymous_variant 0.69 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.69 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.64 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.6 isoniazid
kasA 2519131 c.1017G>C synonymous_variant 0.6 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.55 isoniazid
kasA 2519141 c.1027C>T synonymous_variant 0.55 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.55 isoniazid
kasA 2519158 c.1044C>A synonymous_variant 0.55 isoniazid
kasA 2519203 c.1089C>T synonymous_variant 0.6 isoniazid
kasA 2519209 c.1095C>G synonymous_variant 0.55 isoniazid
folC 2747026 c.573C>G synonymous_variant 0.7 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 0.7 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 0.7 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747098 c.501C>G synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747101 c.498G>A synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.58 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.58 para-aminosalicylic_acid
folC 2747128 p.Ala157Gly missense_variant 0.54 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.54 para-aminosalicylic_acid
folC 2747155 c.444G>C synonymous_variant 0.5 para-aminosalicylic_acid
Rv2477c 2783002 c.1041T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.8 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783084 p.Val320Gln missense_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783413 c.630G>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783432 c.610_611delAGinsTC synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783449 c.594C>G synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.63 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783908 c.135G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>T synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Leu missense_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783963 p.Ser27Asn missense_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783967 c.76T>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783974 c.69C>T synonymous_variant 0.79 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783986 c.57G>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783989 c.54G>A synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.79 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784001 c.42G>A synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784004 c.39G>A synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784010 c.33C>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3064928 c.1264T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064932 c.1260T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064935 c.1257A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064941 p.Gln417Glu missense_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064947 c.1245A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064950 c.1242C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064958 p.Ser412Arg missense_variant 0.6 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3064969 p.Lys408Ala missense_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064974 c.1218T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064980 c.1212C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065028 p.Val388Ile missense_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>G synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065060 p.Ala378Ser missense_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066006 c.186G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067316 c.630A>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067328 c.618G>C synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067364 c.582C>T synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067423 c.523C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067464 p.Ile161Thr missense_variant 0.8 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067478 c.468C>T synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067862 c.84C>T synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.8 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.64 para-aminosalicylic_acid
thyX 3067889 p.Ala19Pro missense_variant 0.64 para-aminosalicylic_acid
thyX 3067892 p.Leu18Thr missense_variant 0.64 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.64 para-aminosalicylic_acid
thyX 3067910 c.36C>T synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067934 c.12C>G synonymous_variant 0.47 para-aminosalicylic_acid
lpqB 3624386 c.525C>G synonymous_variant 0.7 rifampicin
bedaquiline
mtrB 3625623 p.Thr331Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625627 p.Asp329Glu missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625633 c.981C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625636 p.Ala326Glu missense_variant 0.91 rifampicin
bedaquiline
mtrB 3625648 p.Tyr322His missense_variant 0.86 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.87 rifampicin
bedaquiline
lpqB 3625672 c.-762G>C upstream_gene_variant 0.89 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.85 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625695 c.-785C>T upstream_gene_variant 0.88 rifampicin
bedaquiline
lpqB 3625702 c.-792C>T upstream_gene_variant 0.88 rifampicin
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.86 rifampicin Uncertain significance
bedaquiline
mtrB 3625761 p.Gln285Glu missense_variant 0.86 rifampicin Uncertain significance
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 0.86 rifampicin
bedaquiline
lpqB 3625765 c.-855C>A upstream_gene_variant 0.86 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625819 c.795G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625840 c.-930A>G upstream_gene_variant 0.89 rifampicin
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 0.87 rifampicin
bedaquiline
mtrB 3625867 c.747A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625876 c.-966G>A upstream_gene_variant 0.83 rifampicin
bedaquiline
lpqB 3625879 c.-969G>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3625882 c.732G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625885 c.-975G>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3625891 c.723G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625899 p.Val239Leu missense_variant 0.8 rifampicin
bedaquiline
mtrB 3626696 c.-83T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3626723 c.-110C>G upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrA 3626729 p.Lys207Gln missense_variant 0.85 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3626735 c.-122C>G upstream_gene_variant 0.77 rifampicin
bedaquiline
mtrA 3626741 c.609C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626750 c.-137T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626776 c.-163A>C upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.77 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626789 c.561C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626792 c.-179G>C upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrB 3626804 c.-191A>C upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3626816 c.-203G>T upstream_gene_variant 0.83 rifampicin
bedaquiline
mtrA 3626822 p.Asp176Glu missense_variant 0.85 rifampicin
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627032 c.-419G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627053 c.-440C>G upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrA 3627056 c.294C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrA 3627068 c.282T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627110 c.-497G>C upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.83 rifampicin
bedaquiline
mtrA 3627131 p.Ala73Lys missense_variant 0.8 rifampicin
bedaquiline
mtrB 3627134 c.-521C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3627149 c.-536G>C upstream_gene_variant 0.8 rifampicin
bedaquiline
rpoA 3877533 p.Val325Ala missense_variant 1.0 rifampicin
rpoA 3877542 c.966C>G synonymous_variant 0.9 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877548 c.960C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877553 p.Glu319Gln missense_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877569 p.Pro313Ala missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877596 c.912G>C synonymous_variant 0.92 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.92 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.92 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.87 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877689 c.819C>G synonymous_variant 0.84 rifampicin
rpoA 3877692 c.816G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877707 c.801G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 0.91 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877788 c.720G>A synonymous_variant 0.88 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 0.89 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877827 c.681C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877842 c.666A>G synonymous_variant 0.95 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877866 c.642G>C synonymous_variant 0.93 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 0.94 rifampicin
rpoA 3877893 c.615C>G synonymous_variant 0.94 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.93 rifampicin
rpoA 3877929 p.Ile193Val missense_variant 0.9 rifampicin Uncertain significance
rpoA 3877962 c.546G>C synonymous_variant 0.81 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.75 rifampicin Uncertain significance
rpoA 3877989 c.519A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878118 c.390T>C synonymous_variant 0.87 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 0.87 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.88 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.89 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Val missense_variant 0.92 rifampicin
rpoA 3878202 c.306G>C synonymous_variant 0.86 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878232 c.276G>C synonymous_variant 0.88 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.93 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.87 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.79 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.76 rifampicin Uncertain significance
rpoA 3878298 c.210A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.75 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.73 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.75 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.75 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.6 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.6 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.83 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.83 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.83 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.83 rifampicin
rpoA 3879097 c.-590C>G upstream_gene_variant 0.83 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.85 rifampicin
rpoA 3879124 c.-618_-617delTGinsGT upstream_gene_variant 0.85 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.92 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.85 rifampicin
rpoA 3879178 c.-671T>G upstream_gene_variant 0.85 rifampicin
rpoA 3879190 c.-683C>A upstream_gene_variant 0.83 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.8 rifampicin
clpC1 4038539 c.2166G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.7 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.62 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 0.67 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.67 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.56 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.59 pyrazinamide
clpC1 4038674 c.2031C>T synonymous_variant 0.59 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.59 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2013C>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.63 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.63 pyrazinamide
clpC1 4038722 c.1983G>C synonymous_variant 0.56 pyrazinamide
clpC1 4038725 p.Thr660Cys missense_variant 0.56 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.74 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.72 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.72 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.76 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4038809 p.Gln632Ser missense_variant 0.73 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.92 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.91 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.83 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.83 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.83 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.8 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.81 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.85 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038944 c.1761C>T synonymous_variant 0.83 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.82 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4039001 p.Asn568Glu missense_variant 0.76 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039031 c.1674T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039073 c.1632C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039109 c.1596C>T synonymous_variant 0.86 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039139 c.1566G>A synonymous_variant 0.93 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.97 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039199 c.1506C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039244 c.1461G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039250 c.1455C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039277 c.1428C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 0.95 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039319 c.1386T>A synonymous_variant 0.94 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 0.94 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.94 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.94 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039358 c.1347C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.91 pyrazinamide
clpC1 4039394 c.1311G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.86 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.86 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039517 c.1188C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039541 c.1164C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039581 p.Thr375Ser missense_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039601 c.1104G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039631 c.1074C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039649 c.1056G>T synonymous_variant 0.96 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039694 c.1011G>A synonymous_variant 0.88 pyrazinamide
clpC1 4039697 c.1008C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039736 c.969C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.84 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039855 c.850C>T synonymous_variant 0.81 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039889 c.816G>T synonymous_variant 0.79 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.78 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039916 c.789T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039943 c.762G>A synonymous_variant 0.89 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.9 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039994 c.711G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040001 p.His235Ala missense_variant 1.0 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040006 c.699C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040135 c.570C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040138 c.567G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.95 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.93 pyrazinamide
clpC1 4040213 c.492T>A synonymous_variant 0.93 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.82 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040234 c.471C>A synonymous_variant 0.91 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040303 c.402G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 0.92 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040345 c.360C>A synonymous_variant 0.76 pyrazinamide
clpC1 4040351 c.354C>T synonymous_variant 0.75 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.8 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.8 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.8 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.76 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.87 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.86 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040414 c.291G>A synonymous_variant 0.83 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040462 c.243C>G synonymous_variant 0.76 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.73 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>G synonymous_variant 0.68 pyrazinamide
clpC1 4040513 c.192G>A synonymous_variant 0.86 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.84 pyrazinamide
clpC1 4040539 c.166C>T synonymous_variant 0.81 pyrazinamide
clpC1 4040540 c.165G>C synonymous_variant 0.81 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040573 c.132T>G synonymous_variant 0.79 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.77 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.77 pyrazinamide
clpC1 4040594 c.111G>C synonymous_variant 0.77 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.83 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.83 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.83 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.83 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.91 pyrazinamide
glpK 4138661 c.1095T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138682 c.1074C>A synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.58 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.58 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.58 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.67 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.71 ethambutol
embC 4241084 p.Leu408Ala missense_variant 0.75 ethambutol
embC 4241123 c.1261C>A synonymous_variant 0.83 ethambutol
embC 4241135 p.Val425Leu missense_variant 0.83 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embC 4241153 p.Ile431Leu missense_variant 0.8 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.79 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embC 4241162 p.Leu434Met missense_variant 0.86 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.77 ethambutol
embC 4241179 c.1317G>T synonymous_variant 0.75 ethambutol
embC 4241182 c.1320G>C synonymous_variant 0.75 ethambutol
embC 4241188 c.1326C>G synonymous_variant 0.73 ethambutol
embC 4241194 c.1332C>G synonymous_variant 0.73 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.77 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.6 ethambutol Not assoc w R - Interim