Run ID: SRR1180172
Sample name:
Date: 2024-10-05T07:34:12.231631
Number of reads: 1635197
Percentage reads mapped: 54.92
Median coverage: 36.0
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.8.1 | M.bovis | None | 0.07 |
lineage2 | East-Asian | RD105 | 0.98 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 0.95 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Met482Ile | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
embB | 4247448 | p.His312Arg | missense_variant | 0.27 | ethambutol | Mutation from literature | |
embB | 4247959 | p.Met482Ile | missense_variant | 0.23 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 540 | c.540C>T | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 549 | c.549C>T | synonymous_variant | 0.21 | isoniazid | |
dnaA | 552 | c.552G>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 558 | c.558G>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 567 | c.567C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 588 | c.588A>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 591 | c.591C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 594 | c.594C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 597 | c.597C>T | synonymous_variant | 0.2 | isoniazid | |
dnaA | 600 | c.600T>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 609 | c.609C>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 909 | c.909A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 912 | c.912T>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 0.24 | isoniazid | |
dnaA | 930 | c.930G>A | synonymous_variant | 0.23 | isoniazid | |
dnaA | 939 | c.939C>T | synonymous_variant | 0.25 | isoniazid | |
dnaA | 942 | c.942C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.24 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1053 | c.1053C>T | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 1077 | c.1077A>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1107 | c.1107C>T | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1122 | c.1122C>A | synonymous_variant | 0.35 | isoniazid | Not assoc w R - Interim |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1164 | c.1164A>T | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1177 | p.Ala393Ser | missense_variant | 0.21 | isoniazid | |
dnaA | 1180 | c.1180C>T | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1203 | c.1203T>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1215 | c.1215C>T | synonymous_variant | 0.34 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.29 | isoniazid | |
dnaA | 1224 | c.1224C>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1239 | c.1239G>A | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.43 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1291 | c.1291_1293delCTTinsTTA | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1299 | c.1299G>T | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1317 | c.1317A>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1323 | c.1323C>T | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 1329 | c.1329A>G | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1332 | c.1332A>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1347 | c.1347C>T | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1356 | c.1356T>C | synonymous_variant | 0.34 | isoniazid | Not assoc w R - Interim |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1374 | c.1374G>A | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1428 | c.1428C>A | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1434 | c.1434C>A | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1437 | c.1437G>A | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1441 | c.1441C>T | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1470 | c.1470C>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1473 | c.1473T>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 1479 | c.1479C>T | synonymous_variant | 0.2 | isoniazid | |
gyrB | 6151 | c.912C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6157 | c.918C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6160 | c.921C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6355 | c.-947G>A | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940_-938delTTGinsCTA | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6631 | c.-671C>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6644 | c.-658_-657delAGinsTC | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6680 | c.1441C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6721 | c.1482C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6781 | c.-521C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6835 | c.-467C>T | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6872 | c.-430T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6916 | c.-386G>T | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6941 | c.-361C>T | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7388 | c.87C>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7412 | c.111C>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7424 | c.123G>A | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7433 | c.132G>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7760 | c.459C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>T | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7838 | c.537C>T | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7841 | c.540C>T | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8213 | c.912C>T | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8222 | c.921C>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8228 | c.927G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8235 | c.934_936delTTAinsCTG | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8252 | c.951G>A | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.36 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8321 | c.1020C>T | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8337 | c.1036_1038delCTAinsTTG | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.35 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8393 | c.1092T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8492 | c.1191G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8501 | c.1200G>A | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8507 | c.1206C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8510 | c.1209G>A | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251C>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8576 | c.1275C>G | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8609 | c.1308G>C | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8645 | c.1344C>T | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8664 | c.1363C>T | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8855 | c.1554C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8876 | c.1575C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8930 | c.1629C>T | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>A | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8957 | c.1656C>T | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.34 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>A | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.25 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9062 | c.1761C>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9128 | c.1827C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9147 | p.Gly616Ser | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9185 | c.1884C>T | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9192 | c.1891C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9203 | c.1902G>A | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9248 | c.1947G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9251 | c.1950G>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9287 | c.1986G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490815 | c.33G>T | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490818 | c.36C>T | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490830 | c.48A>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490851 | c.69A>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490854 | c.72C>T | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490857 | c.75C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490869 | c.87C>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490887 | c.105G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491022 | c.240C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491043 | c.261T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491058 | c.276C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491064 | c.282A>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491082 | c.300T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491083 | p.Val101Ile | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491097 | c.315G>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491112 | c.330G>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491115 | c.333G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491289 | c.507C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491290 | p.Val170Ile | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491310 | c.528C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491316 | c.534C>A | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491320 | p.Ala180Gln | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491538 | c.756G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491623 | p.Ala281Thr | missense_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491637 | c.855C>A | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491640 | c.858G>C | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
mshA | 575761 | c.414C>T | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>A | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
mshA | 575851 | c.504C>T | synonymous_variant | 0.35 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575860 | c.513G>A | synonymous_variant | 0.37 | isoniazid | |
ethionamide | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.37 | isoniazid | |
ethionamide | ||||||
mshA | 575878 | c.531A>G | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
mshA | 575905 | c.558G>C | synonymous_variant | 0.54 | isoniazid | |
ethionamide | ||||||
mshA | 575907 | p.Ala187Val | missense_variant | 0.47 | isoniazid | Not assoc w R |
ethionamide | Not assoc w R | |||||
mshA | 575916 | p.Asp190Ala | missense_variant | 0.49 | isoniazid | |
ethionamide | ||||||
mshA | 575924 | p.Gly193Ile | missense_variant | 0.43 | isoniazid | |
ethionamide | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.34 | isoniazid | |
ethionamide | ||||||
mshA | 575950 | c.603C>G | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
mshA | 575971 | c.624C>T | synonymous_variant | 0.34 | isoniazid | |
ethionamide | ||||||
mshA | 576193 | c.846T>C | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 576202 | c.855T>G | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 576205 | c.858G>A | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
mshA | 576214 | c.867G>A | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
mshA | 576220 | c.873C>G | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
mshA | 576223 | c.876G>C | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
mshA | 576233 | p.Ile296Val | missense_variant | 0.2 | isoniazid | |
ethionamide | ||||||
mshA | 576247 | c.900A>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.31 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.3 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619615 | c.-276C>T | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619627 | c.-264C>T | upstream_gene_variant | 0.31 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>G | upstream_gene_variant | 0.31 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619647 | c.-244T>C | upstream_gene_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619669 | c.-222G>C | upstream_gene_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619672 | c.-219A>G | upstream_gene_variant | 0.33 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619681 | c.-210G>C | upstream_gene_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620307 | c.417C>T | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657647 | c.-179_-177delGTCinsATT | upstream_gene_variant | 0.16 | ethionamide | |
Rv0565c | 657689 | c.-219A>C | upstream_gene_variant | 0.18 | ethionamide | |
hadA | 731753 | c.-177A>T | upstream_gene_variant | 0.26 | isoniazid | |
hadA | 731768 | c.-162G>A | upstream_gene_variant | 0.37 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.39 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.42 | isoniazid | |
hadA | 731798 | c.-132C>G | upstream_gene_variant | 0.45 | isoniazid | |
hadA | 731825 | c.-105G>C | upstream_gene_variant | 0.37 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731849 | c.-81C>T | upstream_gene_variant | 0.28 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.28 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.31 | isoniazid | |
nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
nusG | 734093 | c.-161A>G | upstream_gene_variant | 0.2 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 0.21 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.18 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.19 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.18 | rifampicin | Uncertain significance |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.23 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.24 | rifampicin | |
nusG | 734143 | c.-111C>T | upstream_gene_variant | 0.22 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.22 | rifampicin | |
nusG | 734150 | c.-104G>C | upstream_gene_variant | 0.26 | rifampicin | |
nusG | 734407 | p.Val52Ile | missense_variant | 0.37 | rifampicin | |
nusG | 734415 | c.162C>T | synonymous_variant | 0.38 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.4 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.42 | rifampicin | |
nusG | 734439 | c.186C>G | synonymous_variant | 0.48 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.45 | rifampicin | |
nusG | 734457 | c.204C>T | synonymous_variant | 0.43 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.41 | rifampicin | |
nusG | 734505 | c.252G>A | synonymous_variant | 0.43 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.39 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.39 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.29 | rifampicin | |
nusG | 734826 | c.573A>G | synonymous_variant | 0.35 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
nusG | 734847 | c.594T>C | synonymous_variant | 0.36 | rifampicin | |
nusG | 734850 | c.597C>G | synonymous_variant | 0.36 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.36 | rifampicin | |
nusG | 734870 | p.Ser206Asn | missense_variant | 0.37 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 0.38 | rifampicin | |
nusG | 734905 | c.652C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
nusG | 734910 | c.657C>G | synonymous_variant | 0.26 | rifampicin | |
nusG | 734913 | c.660C>G | synonymous_variant | 0.25 | rifampicin | |
nusG | 734940 | c.687G>A | synonymous_variant | 0.19 | rifampicin | |
nusG | 734943 | c.690G>C | synonymous_variant | 0.17 | rifampicin | |
nusG | 734946 | c.693C>T | synonymous_variant | 0.17 | rifampicin | |
nusG | 734951 | p.Gly233Ala | missense_variant | 0.17 | rifampicin | |
mmaA3 | 738315 | c.-166G>A | upstream_gene_variant | 0.26 | isoniazid | |
mmaA3 | 738346 | c.-198_-197delCTinsGC | upstream_gene_variant | 0.26 | isoniazid | |
mmaA3 | 738348 | c.-199G>C | upstream_gene_variant | 0.27 | isoniazid | |
rpoB | 760088 | c.282C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760115 | c.309C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.39 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760145 | c.339C>G | synonymous_variant | 0.45 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760274 | c.468G>A | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760356 | p.Thr184Ser | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.32 | rifampicin | |
rpoB | 760403 | c.597C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760415 | c.609C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760478 | c.672C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>T | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoB | 760533 | p.Val243His | missense_variant | 0.29 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760556 | c.750G>A | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.35 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.35 | rifampicin | |
rpoB | 760598 | c.792C>T | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760748 | c.942C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760754 | c.948G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760755 | p.His317Asn | missense_variant | 0.22 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.22 | rifampicin | |
rpoB | 760763 | c.957C>T | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Ser | missense_variant | 0.19 | rifampicin | |
rpoB | 760850 | c.1044G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760856 | c.1050C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Thr | missense_variant | 0.29 | rifampicin | |
rpoB | 760877 | c.1071G>T | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.37 | rifampicin | |
rpoB | 760916 | c.1110C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760919 | c.1113C>T | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760964 | c.1158C>T | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>T | synonymous_variant | 0.43 | rifampicin | |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761133 | c.1327_1329delTTGinsCTC | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761180 | c.1374A>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761192 | c.1386C>G | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761204 | c.1398C>T | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761240 | c.1434C>T | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761282 | c.1476C>G | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.47 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761367 | p.Glu521Gln | missense_variant | 0.41 | rifampicin | |
rpoB | 761374 | p.Val523Asp | missense_variant | 0.39 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.33 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.31 | rifampicin | |
rpoB | 761465 | c.1659G>T | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761471 | c.1665C>T | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761477 | c.1671C>T | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761483 | c.1677G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761504 | c.1698C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761516 | c.1710G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761540 | c.1734C>T | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761561 | c.1755C>G | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761564 | c.1758G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 761582 | c.1776G>A | synonymous_variant | 0.6 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.49 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761666 | c.1860G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761669 | c.1863C>T | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761675 | c.1869G>T | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.29 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.3 | rifampicin | |
rpoB | 761786 | c.1980C>A | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.32 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761819 | c.2013G>A | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.38 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.41 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761867 | c.2061C>A | synonymous_variant | 0.62 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.66 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.36 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.35 | rifampicin | |
rpoB | 761921 | c.2115C>T | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761933 | c.2127G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761955 | p.Ile717Val | missense_variant | 0.26 | rifampicin | Uncertain significance |
rpoB | 761969 | c.2163G>A | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.44 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762050 | c.2244G>A | synonymous_variant | 0.47 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.44 | rifampicin | Uncertain significance |
rpoB | 762138 | c.2332C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762179 | c.2373C>T | synonymous_variant | 0.55 | rifampicin | |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 762239 | c.2433G>A | synonymous_variant | 0.41 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 762350 | c.2544C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.35 | rifampicin | |
rpoB | 762368 | c.2562G>A | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.33 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoC | 762401 | c.-969G>T | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.41 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 762443 | c.-927G>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762452 | c.2646G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 762491 | c.2685T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762507 | p.Leu901Met | missense_variant | 0.33 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoC | 762524 | c.-846G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762788 | c.2982G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 0.28 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 762795 | p.Asp997Asn | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoC | 762800 | c.-570C>A | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 762824 | c.-546C>T | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762827 | c.-543G>T | upstream_gene_variant | 0.38 | rifampicin | |
rpoB | 762833 | c.3027C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 762920 | c.-450C>G | upstream_gene_variant | 0.48 | rifampicin | |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>A | upstream_gene_variant | 0.46 | rifampicin | |
rpoB | 762989 | c.3183G>A | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 763082 | c.-288C>G | upstream_gene_variant | 0.49 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763103 | c.-267G>A | upstream_gene_variant | 0.49 | rifampicin | |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763133 | c.-237G>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.35 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoC | 763402 | c.33C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763408 | c.39T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763423 | c.54G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>A | synonymous_variant | 0.57 | rifampicin | |
rpoC | 763573 | c.204G>T | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 763615 | c.246G>A | synonymous_variant | 0.49 | rifampicin | |
rpoC | 763618 | c.249C>T | synonymous_variant | 0.49 | rifampicin | |
rpoC | 763621 | c.252C>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 763636 | c.267T>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763681 | c.312C>A | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 763768 | c.399C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763781 | p.Ser138Ala | missense_variant | 0.42 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.4 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 763836 | p.Ala156Val | missense_variant | 0.43 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.39 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.38 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763888 | c.519G>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763924 | c.555G>A | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763969 | c.600C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763978 | c.609C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763991 | p.Ile208Leu | missense_variant | 0.46 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.41 | rifampicin | |
rpoC | 764044 | c.675T>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764056 | c.687G>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764080 | c.711C>T | synonymous_variant | 0.49 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764194 | p.Glu275Asp | missense_variant | 0.32 | rifampicin | |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.32 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764218 | c.849C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764242 | c.873C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764245 | c.876C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764254 | c.885G>A | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764260 | c.891G>A | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764263 | c.894G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764317 | c.948C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764320 | c.951C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764339 | c.970C>T | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764353 | c.984G>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764428 | c.1059G>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764452 | c.1083T>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764455 | c.1086G>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764857 | c.1488G>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764875 | c.1506C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764887 | c.1518G>A | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764888 | c.1519_1521delTTGinsCTC | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764896 | c.1527C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764902 | c.1533C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764908 | c.1539G>A | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764953 | c.1584G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764983 | c.1614T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765052 | c.1683C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 765085 | c.1716T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765328 | p.His653Gln | missense_variant | 0.26 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoC | 765334 | c.1965C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765343 | c.1974G>A | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765367 | c.1998C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765370 | c.2001G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.41 | rifampicin | Uncertain significance |
rpoC | 765404 | c.2035C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>A | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765547 | c.2178C>A | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765592 | c.2223C>T | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765622 | p.Glu751Asp | missense_variant | 0.36 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765685 | c.2316G>A | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765728 | p.Gln787Lys | missense_variant | 0.48 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.43 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 765907 | c.2538G>A | synonymous_variant | 0.6 | rifampicin | |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765952 | c.2583G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 765973 | c.2604C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765991 | c.2622C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766003 | c.2634G>A | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.4 | rifampicin | |
rpoC | 766061 | p.Val898Ile | missense_variant | 0.37 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.35 | rifampicin | |
rpoC | 766096 | c.2727G>T | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 766148 | p.Thr927Ala | missense_variant | 0.38 | rifampicin | Uncertain significance |
rpoC | 766178 | p.Ile937Val | missense_variant | 0.33 | rifampicin | |
rpoC | 766185 | p.Glu939Ala | missense_variant | 0.28 | rifampicin | |
rpoC | 766192 | c.2823T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766193 | p.Gln942Glu | missense_variant | 0.21 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.24 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.24 | rifampicin | |
rpoC | 766288 | c.2919C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766294 | c.2925C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766315 | c.2946C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766333 | c.2964G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766369 | c.3000C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766402 | c.3033C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766492 | c.3123T>A | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766500 | p.Ala1044Val | missense_variant | 0.37 | rifampicin | Uncertain significance |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.51 | rifampicin | |
rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.52 | rifampicin | |
rpoC | 766540 | c.3171C>T | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766570 | c.3201T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766579 | c.3210C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 766585 | c.3216T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.59 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766660 | c.3291G>A | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766666 | c.3297C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 766769 | c.3400C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766801 | c.3432C>A | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766978 | c.3609C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.4 | rifampicin | |
rpoC | 767044 | c.3675G>A | synonymous_variant | 0.46 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.49 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.52 | rifampicin | |
rpoC | 767152 | c.3783T>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 767158 | c.3789T>A | synonymous_variant | 0.44 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.43 | rifampicin | |
rpoC | 767185 | c.3816G>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 767200 | c.3831G>A | synonymous_variant | 0.46 | rifampicin | |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.46 | rifampicin | |
rpoC | 767275 | c.3906T>A | synonymous_variant | 0.37 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 0.35 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.3 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.17 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776030 | c.2451G>A | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | bedaquiline | Not assoc w R |
clofazimine | Not assoc w R | |||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | bedaquiline | |
clofazimine | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781598 | c.39G>C | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.31 | streptomycin | |
rpsL | 781622 | c.63C>G | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.36 | streptomycin | Not assoc w R - Interim |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781763 | c.204C>G | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781766 | c.207C>T | synonymous_variant | 0.37 | streptomycin | Not assoc w R - Interim |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781820 | c.261G>T | synonymous_variant | 0.48 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.49 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.45 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781886 | c.327C>T | synonymous_variant | 0.42 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.44 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.32 | streptomycin | Uncertain significance |
rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 0.31 | streptomycin | |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.34 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800693 | c.-116A>C | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800714 | c.-95C>T | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800715 | c.-94_-92delATCinsCTT | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.32 | linezolid | |
rplC | 800744 | c.-65G>A | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800759 | c.-50C>T | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800762 | c.-47T>G | upstream_gene_variant | 0.21 | linezolid | |
rplC | 801123 | c.315C>T | synonymous_variant | 0.18 | linezolid | Not assoc w R - Interim |
rplC | 801132 | c.324T>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801136 | p.Ser110Ala | missense_variant | 0.25 | linezolid | |
rplC | 801141 | c.333C>T | synonymous_variant | 0.26 | linezolid | |
rplC | 801147 | c.339T>C | synonymous_variant | 0.26 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.26 | linezolid | |
rplC | 801156 | c.348T>G | synonymous_variant | 0.28 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.36 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.36 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.38 | linezolid | |
rplC | 801207 | c.399C>T | synonymous_variant | 0.39 | linezolid | |
rplC | 801210 | c.402T>C | synonymous_variant | 0.38 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.25 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.2 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.2 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.25 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801339 | c.531T>G | synonymous_variant | 0.23 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.24 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.21 | linezolid | |
rplC | 801349 | p.Leu181Val | missense_variant | 0.21 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801378 | c.570C>T | synonymous_variant | 0.25 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.2 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801408 | c.600C>A | synonymous_variant | 0.2 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1303480 | p.Gln184Glu | missense_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303492 | c.562T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303506 | c.576C>T | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.41 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303537 | p.Arg203Leu | missense_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303542 | c.612C>G | synonymous_variant | 0.45 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303593 | c.663G>A | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303596 | c.666G>C | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303716 | c.786C>T | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303722 | c.792C>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303731 | c.801A>G | synonymous_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.36 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303750 | c.820_822delTTAinsCTG | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303779 | c.849G>A | synonymous_variant | 0.49 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>T | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303788 | c.858T>C | synonymous_variant | 0.46 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303794 | c.864A>G | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304619 | c.1689G>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304628 | c.1698G>T | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.32 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304796 | c.1866G>A | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304799 | c.1869G>C | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304823 | c.1893C>T | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.49 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.52 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304896 | c.1966C>T | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304915 | p.Asp662Gly | missense_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.44 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.39 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304970 | c.2040G>C | synonymous_variant | 0.37 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304988 | c.2058G>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305144 | c.2214G>A | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305150 | c.2220C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305154 | c.2224T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305173 | p.Asn748Ser | missense_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305177 | c.2247A>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305181 | c.2251T>C | synonymous_variant | 0.33 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305186 | c.2256C>T | synonymous_variant | 0.34 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364667 | c.255T>C | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364671 | c.259C>T | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364676 | c.264C>G | synonymous_variant | 0.25 | pyrazinamide | |
sigE | 1364691 | c.279T>C | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364721 | c.309C>G | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364925 | c.513C>G | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1364931 | c.519C>G | synonymous_variant | 0.35 | pyrazinamide | |
sigE | 1364952 | c.540A>C | synonymous_variant | 0.3 | pyrazinamide | |
sigE | 1364955 | c.543G>C | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364964 | c.552T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364976 | c.564T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364979 | c.567C>G | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364980 | c.568T>C | synonymous_variant | 0.32 | pyrazinamide | |
sigE | 1364984 | p.Ala191Asp | missense_variant | 0.34 | pyrazinamide | |
sigE | 1365006 | c.594T>C | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1365012 | c.600G>C | synonymous_variant | 0.36 | pyrazinamide | |
sigE | 1365030 | c.618C>T | synonymous_variant | 0.37 | pyrazinamide | |
sigE | 1365033 | c.621G>A | synonymous_variant | 0.36 | pyrazinamide | |
sigE | 1365036 | c.624T>C | synonymous_variant | 0.4 | pyrazinamide | |
sigE | 1365042 | c.630G>C | synonymous_variant | 0.41 | pyrazinamide | |
sigE | 1365063 | c.651A>T | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1365072 | c.660G>C | synonymous_variant | 0.32 | pyrazinamide | |
sigE | 1365078 | c.666C>G | synonymous_variant | 0.32 | pyrazinamide | |
sigE | 1365081 | c.669G>T | synonymous_variant | 0.32 | pyrazinamide | |
sigE | 1365084 | c.672G>C | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1365087 | c.675A>C | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1365090 | c.678T>C | synonymous_variant | 0.3 | pyrazinamide | |
sigE | 1365099 | c.687A>C | synonymous_variant | 0.26 | pyrazinamide | |
sigE | 1365111 | c.699C>T | synonymous_variant | 0.2 | pyrazinamide | |
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
pyrazinamide | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.41 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.44 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.44 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.34 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472029 | n.185_188delGGGA | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.36 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472445 | n.601_604delTCTC | non_coding_transcript_exon_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472451 | n.606_607insCGGG | non_coding_transcript_exon_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472460 | n.615T>C | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472463 | n.618G>C | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472686 | n.841G>A | non_coding_transcript_exon_variant | 0.57 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 0.27 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 0.27 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 0.27 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.27 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472859 | n.1014G>C | non_coding_transcript_exon_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.34 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.4 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473676 | n.19G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473797 | n.140G>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1473887 | n.230T>A | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474002 | n.345G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474007 | n.350A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474061 | n.404T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1474135 | n.478G>A | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474156 | n.499G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474163 | n.506C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474286 | n.629C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474291 | n.635_644delTTCCTCTCCG | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474303 | n.646A>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474306 | n.651_655delGGTGG | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474409 | n.756_774delACCCACACGCGCATACGCG | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474433 | n.776G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474435 | n.779_783delTGAAT | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475018 | n.1361G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475027 | n.1370G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475028 | n.1371G>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475062 | n.1405A>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475379 | n.1722G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475398 | n.1741C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475446 | n.1789G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475453 | n.1796T>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475487 | n.1830C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475605 | n.1948A>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475637 | n.1980T>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475759 | n.2102_2106delCCCGCinsTCGT | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475999 | n.2342G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1476035 | n.2378G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476045 | n.2388G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476077 | n.2420T>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476104 | n.2448delG | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476301 | n.2644A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1476595 | n.2938C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476602 | n.2945G>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476740 | n.3083G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
inhA | 1673490 | c.-712A>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673494 | c.-708C>T | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673499 | c.-703T>G | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673505 | c.-697A>C | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1673523 | c.-679G>T | upstream_gene_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1673535 | c.-667A>C | upstream_gene_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1673721 | c.-481C>T | upstream_gene_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1673727 | c.-475C>T | upstream_gene_variant | 0.22 | isoniazid | Uncertain significance |
ethionamide | ||||||
inhA | 1673733 | c.-469G>C | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1673749 | c.-453_-452delAAinsCG | upstream_gene_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1673758 | c.-444A>G | upstream_gene_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674810 | c.609C>G | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674813 | c.612C>T | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674819 | c.618G>T | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674840 | c.639C>T | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674927 | c.726G>A | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674939 | c.738G>T | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.17 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.27 | pyrazinamide | Uncertain significance |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833595 | c.54T>G | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833703 | c.162C>T | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833749 | p.Ile70Leu | missense_variant | 0.57 | pyrazinamide | Not assoc w R |
rpsA | 1833760 | c.219C>T | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833782 | p.Ser81Thr | missense_variant | 0.45 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833799 | c.258C>A | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833808 | c.267G>T | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833820 | c.279G>A | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833838 | c.297G>T | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833892 | c.351G>A | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833904 | c.363G>A | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833934 | c.393C>T | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834051 | c.510G>A | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834252 | c.711C>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834255 | c.714C>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834258 | c.717G>A | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834259 | c.718_720delCTAinsTTG | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834279 | c.738C>T | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834282 | c.741C>T | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834294 | c.753G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834387 | c.846C>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834414 | c.873C>T | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834432 | c.891G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834477 | c.936C>T | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834495 | c.954G>A | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834517 | c.976C>T | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834556 | p.Ala339Thr | missense_variant | 0.53 | pyrazinamide | Uncertain significance |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834612 | c.1071G>A | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834615 | c.1074C>T | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834624 | c.1083G>A | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.56 | pyrazinamide | |
rpsA | 1834666 | c.1125G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834669 | c.1128G>C | synonymous_variant | 0.45 | pyrazinamide | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.26 | linezolid | |
tsnR | 1853375 | c.-231G>T | upstream_gene_variant | 0.26 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853450 | c.-156G>A | upstream_gene_variant | 0.19 | linezolid | |
tsnR | 1853453 | c.-153G>C | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.26 | linezolid | |
tsnR | 1853468 | c.-138C>T | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853485 | c.-121G>C | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853489 | c.-117C>T | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853495 | c.-111G>C | upstream_gene_variant | 0.24 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2063541 | c.1188A>G | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063550 | c.1179C>G | synonymous_variant | 0.31 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063574 | c.1155C>G | synonymous_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063583 | c.1146G>C | synonymous_variant | 0.31 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063588 | c.1141T>C | synonymous_variant | 0.32 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2063598 | c.1131T>C | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064975 | c.-247G>C | upstream_gene_variant | 0.27 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064981 | c.-253G>C | upstream_gene_variant | 0.28 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.27 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
bacA | 2064996 | c.-268G>A | upstream_gene_variant | 0.29 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101912 | c.1131G>A | synonymous_variant | 0.28 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.3 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101939 | c.1104A>C | synonymous_variant | 0.39 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 0.39 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101964 | p.Glu360Ala | missense_variant | 0.38 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101966 | c.1077T>A | synonymous_variant | 0.38 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 0.43 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101980 | p.Asn355Asp | missense_variant | 0.43 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101987 | c.1056C>G | synonymous_variant | 0.44 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101990 | c.1053G>C | synonymous_variant | 0.44 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101999 | c.1044G>A | synonymous_variant | 0.41 | isoniazid | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2102020 | c.1023A>G | synonymous_variant | 0.39 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102023 | c.1020G>C | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102026 | c.1017G>T | synonymous_variant | 0.38 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102035 | c.1008C>G | synonymous_variant | 0.38 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102047 | c.996G>C | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
delamanid | ||||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2102050 | c.993T>A | synonymous_variant | 0.3 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102059 | c.984T>A | synonymous_variant | 0.29 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102065 | c.978G>C | synonymous_variant | 0.26 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102068 | c.975T>G | synonymous_variant | 0.25 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102686 | c.357G>C | synonymous_variant | 0.24 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102707 | c.336C>T | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102710 | c.333C>T | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102713 | c.330C>T | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102718 | p.Gln109Glu | missense_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102722 | c.321C>G | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
delamanid | ||||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2102731 | c.312C>G | synonymous_variant | 0.27 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.37 | isoniazid | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.32 | isoniazid | |
kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.29 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.21 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.18 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518567 | c.453G>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518687 | p.Asp191Glu | missense_variant | 0.28 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518717 | c.603C>G | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518768 | c.654C>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518792 | c.678C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518843 | c.729T>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518846 | c.732G>C | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518867 | c.753G>A | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518907 | c.793T>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.22 | isoniazid | |
kasA | 2519104 | c.990T>A | synonymous_variant | 0.18 | isoniazid | |
kasA | 2519119 | c.1005G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2519146 | c.1032C>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519152 | c.1038G>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519161 | c.1047G>A | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519188 | c.1074G>A | synonymous_variant | 0.38 | isoniazid | |
kasA | 2519197 | c.1083G>C | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519203 | c.1089C>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519206 | c.1092C>T | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519221 | c.1107G>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2519227 | c.1113G>C | synonymous_variant | 0.22 | isoniazid | |
eis | 2714526 | c.805_806delAC | frameshift_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
folC | 2746584 | c.1015T>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
folC | 2746591 | c.1008C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2746597 | c.1002C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2746609 | c.990T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
folC | 2746612 | c.987C>T | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2746621 | c.978C>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
folC | 2746624 | c.975C>G | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2746627 | p.Asp324Glu | missense_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2746631 | p.Gly323Val | missense_variant | 0.3 | para-aminosalicylic_acid | |
folC | 2746657 | c.942T>C | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
folC | 2746663 | c.936T>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
folC | 2746975 | c.624T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2746978 | p.Ala207Glu | missense_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2746990 | p.Asp203Glu | missense_variant | 0.24 | para-aminosalicylic_acid | |
folC | 2746999 | c.600T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
folC | 2747002 | c.597T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
folC | 2747299 | c.300C>T | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
folC | 2747302 | c.297A>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
folC | 2747314 | c.285A>T | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
folC | 2747317 | c.282C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
Rv2477c | 2782822 | c.1221G>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782828 | c.1215T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782831 | c.1212G>A | synonymous_variant | 0.19 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782846 | p.Arg399Lys | missense_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782861 | c.1182T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782868 | p.Ala392Ser | missense_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782885 | c.1158G>C | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783146 | c.897G>A | synonymous_variant | 0.19 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.23 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783164 | c.879G>A | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783167 | c.876G>A | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783329 | c.714G>A | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783338 | c.705C>T | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>C | synonymous_variant | 0.51 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783410 | c.633G>C | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.42 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783425 | p.Pro206Ala | missense_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | ||||||
Rv2477c | 2783428 | c.615C>T | synonymous_variant | 0.39 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783449 | c.594C>G | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>G | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783499 | c.544T>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.34 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>A | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.4 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783566 | c.477C>T | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>C | synonymous_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.56 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783611 | c.432C>G | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.58 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.49 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783650 | c.393C>T | synonymous_variant | 0.52 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.52 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.38 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783791 | c.252C>T | synonymous_variant | 0.32 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783836 | c.207C>G | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783842 | c.201C>T | synonymous_variant | 0.41 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783857 | c.186C>G | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.57 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.62 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>A | synonymous_variant | 0.6 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.55 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783967 | c.76T>C | synonymous_variant | 0.4 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.39 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.37 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784016 | c.27G>A | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784390 | c.-348G>C | upstream_gene_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784396 | c.-354A>T | upstream_gene_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784454 | c.-412G>A | upstream_gene_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
pepQ | 2859825 | p.Ala198Ser | missense_variant | 0.22 | bedaquiline | |
clofazimine | ||||||
pepQ | 2859828 | c.591G>A | synonymous_variant | 0.23 | bedaquiline | |
clofazimine | ||||||
pepQ | 2859834 | c.585T>C | synonymous_variant | 0.23 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R - Interim | |||||
Rv2752c | 3065016 | c.1176C>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065022 | c.1170G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065046 | c.1146G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065052 | c.1140G>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065055 | c.1137T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065067 | c.1125C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065097 | c.1095C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065106 | c.1086C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065430 | c.762A>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065475 | c.717C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065612 | p.Thr194Ala | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065614 | p.Asp193Gly | missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065634 | c.558G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065637 | c.555A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065711 | p.Gly161Ser | missense_variant | 0.89 | levofloxacin | Uncertain significance |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
Rv2752c | 3065928 | c.264G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065947 | p.Gly82Ala | missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065949 | c.243C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065957 | c.235T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065958 | c.234G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3065994 | c.198T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066006 | c.186G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066024 | c.168T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066040 | p.Gly51Thr | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066050 | p.Leu48Met | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066054 | c.138T>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066084 | c.108C>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066087 | c.105A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3066118 | p.Asn25Gly | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066126 | c.66C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066129 | c.63G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066135 | c.57C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066138 | c.54C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066420 | c.-229C>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066426 | c.-235T>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066435 | c.-244T>A | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066456 | c.-265A>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066465 | c.-276_-274delGGGinsAGC | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066468 | c.-277C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066471 | c.-280A>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066474 | c.-283G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066480 | c.-291_-289delGCCinsTCT | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066504 | c.-313C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066513 | c.-322C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066596 | c.-405C>T | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066597 | c.-406C>T | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066618 | c.-427A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066633 | c.-442T>C | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066636 | c.-445G>A | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066644 | c.-453T>C | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066672 | c.-481G>C | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066676 | c.-485C>T | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066685 | c.-495_-494delGGinsCC | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066687 | c.-496G>A | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066699 | c.-508C>G | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066707 | c.-516A>G | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066714 | c.-523G>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066717 | c.-526C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066720 | c.-529G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067316 | c.630A>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067325 | c.621A>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067360 | p.Ile196Val | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067382 | c.564C>T | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
thyX | 3067385 | c.561C>G | synonymous_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
thyX | 3067418 | c.528C>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067670 | c.276G>A | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067676 | c.270C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyX | 3067823 | c.123G>C | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
thyX | 3067826 | c.120C>G | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>G | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067883 | c.63C>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067889 | c.57C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3073932 | c.540C>T | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyA | 3073968 | c.504C>G | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyA | 3073983 | c.489C>T | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074001 | c.471C>G | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyA | 3074046 | c.426G>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074053 | p.Arg140Gln | missense_variant | 0.35 | para-aminosalicylic_acid | |
thyA | 3074056 | p.Glu139Pro | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3074082 | c.390G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074089 | p.Ile128Asn | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074121 | p.Asp117Glu | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074130 | c.342G>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074133 | c.339C>T | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3074157 | c.315C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyA | 3074160 | c.312A>G | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyA | 3074163 | p.Ala103Thr | missense_variant | 0.31 | para-aminosalicylic_acid | |
thyA | 3074172 | c.300G>C | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyA | 3074181 | c.291A>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074184 | c.288A>G | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyA | 3074187 | c.285T>C | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyA | 3074196 | c.276G>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074199 | c.273G>A | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.4 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074217 | c.255T>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074220 | c.252A>C | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyA | 3074244 | c.228A>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyA | 3074252 | p.Glu74Gln | missense_variant | 0.26 | para-aminosalicylic_acid | |
thyA | 3074253 | p.His73Gln | missense_variant | 0.26 | para-aminosalicylic_acid | |
thyA | 3074256 | c.216G>A | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyA | 3074267 | p.Ile69Val | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3074268 | c.204T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
fbiD | 3339333 | c.216G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
lpqB | 3624674 | c.237C>T | synonymous_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624680 | c.231T>C | synonymous_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624686 | p.Glu75Gln | missense_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624701 | c.210T>A | synonymous_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624713 | c.198C>T | synonymous_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624749 | c.162G>A | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624755 | c.154_156delTTAinsCTG | synonymous_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624760 | c.151C>T | synonymous_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624776 | c.135T>C | synonymous_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624779 | c.132G>C | synonymous_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624783 | p.Ser43Thr | missense_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624788 | c.123A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3625095 | p.Glu507Gln | missense_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625096 | c.-186C>T | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625102 | c.-192A>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625153 | c.-243C>T | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625174 | c.-264C>A | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625186 | c.-276T>G | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625198 | c.-288C>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625218 | c.-308C>A | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625243 | c.-333T>C | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625255 | c.-345T>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625261 | c.1353C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>A | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625693 | c.-783G>T | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625708 | c.906C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625747 | c.867G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.36 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625762 | c.852A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625804 | c.-896_-894delAGGinsCGA | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625828 | c.-918G>A | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625846 | c.-936G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625860 | p.Ala252Ser | missense_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625864 | c.750T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625888 | c.-978G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626562 | p.Pro18Ser | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3626684 | c.-71G>T | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626702 | c.-91_-89delCTGinsTTA | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626819 | c.-206G>A | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 0.45 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.44 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627113 | c.-500C>T | upstream_gene_variant | 0.38 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627175 | c.175C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627185 | c.-574_-572delTTGinsCTT | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627190 | c.160T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>G | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627239 | c.111C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627278 | c.-665G>T | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627287 | c.-674C>G | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>G | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTC | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877527 | c.981C>G | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3877542 | c.966C>T | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877557 | c.951C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.52 | rifampicin | |
rpoA | 3877617 | c.891G>C | synonymous_variant | 0.51 | rifampicin | |
rpoA | 3877638 | c.870T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.26 | rifampicin | |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.43 | rifampicin | |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3877773 | c.735G>C | synonymous_variant | 0.42 | rifampicin | |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.43 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877887 | c.621G>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3877900 | p.Ser203Thr | missense_variant | 0.37 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.43 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoA | 3877995 | c.513G>A | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878025 | c.483C>T | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878043 | c.465G>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878049 | c.459G>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.44 | rifampicin | |
rpoA | 3878073 | c.435C>T | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878079 | c.429C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3878082 | c.426T>C | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.52 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.58 | rifampicin | |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.42 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3878184 | c.324C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878205 | c.303T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878295 | c.213A>G | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878355 | c.153C>G | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878364 | c.144A>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878391 | c.117T>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3878406 | c.102G>T | synonymous_variant | 0.55 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.56 | rifampicin | |
rpoA | 3878421 | c.87A>T | synonymous_variant | 0.52 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 0.47 | rifampicin | |
rpoA | 3878458 | p.Asn17Ser | missense_variant | 0.52 | rifampicin | |
rpoA | 3878471 | p.Val13Ile | missense_variant | 0.43 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.39 | rifampicin | |
rpoA | 3878484 | c.24C>A | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.31 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.37 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.37 | rifampicin | |
rpoA | 3878837 | c.-331_-330delAAinsGG | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.4 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.41 | rifampicin | Uncertain significance |
rpoA | 3878884 | c.-377C>G | upstream_gene_variant | 0.36 | rifampicin | |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.39 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.37 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.24 | rifampicin | Uncertain significance |
rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878991 | c.-484C>A | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoA | 3879015 | c.-508G>A | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879033 | c.-526C>T | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3879034 | c.-527G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3879037 | c.-530G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoA | 3879061 | c.-554C>T | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.44 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.42 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.41 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.42 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.44 | rifampicin | |
rpoA | 3879190 | c.-683C>T | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879238 | c.-731C>G | upstream_gene_variant | 0.21 | rifampicin | |
ddn | 3986615 | c.-229C>T | upstream_gene_variant | 0.29 | pretomanid | |
delamanid | ||||||
clpC1 | 4038278 | c.2427T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038289 | p.Asn806Asp | missense_variant | 0.31 | pyrazinamide | |
clpC1 | 4038314 | c.2391T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038317 | c.2388G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038323 | c.2382C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038329 | p.Glu792Asp | missense_variant | 0.37 | pyrazinamide | |
clpC1 | 4038350 | c.2355C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038389 | c.2316G>A | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Thr | missense_variant | 0.22 | pyrazinamide | |
clpC1 | 4038499 | p.Ser736Gly | missense_variant | 0.3 | pyrazinamide | |
clpC1 | 4038519 | p.Arg729Gln | missense_variant | 0.35 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.35 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>T | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038647 | c.2058T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.37 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.36 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4038674 | c.2031C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038692 | c.2013C>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038698 | c.2007C>T | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>A | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038845 | c.1858_1860delTCGinsAGC | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038890 | c.1815G>A | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038980 | c.1725C>T | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039021 | c.1684C>T | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039073 | c.1632C>T | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039133 | c.1572C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039136 | c.1569C>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039140 | p.Glu522Val | missense_variant | 0.31 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.47 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039190 | c.1515C>G | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4039223 | c.1482C>T | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039238 | c.1467C>T | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039268 | c.1437C>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>T | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039277 | c.1428C>T | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4039283 | c.1422C>T | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039292 | c.1413C>T | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039319 | p.Ala462Thr | missense_variant | 0.47 | pyrazinamide | |
clpC1 | 4039322 | c.1383T>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>T | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.53 | pyrazinamide | |
clpC1 | 4039355 | c.1350G>T | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>T | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039484 | c.1221T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039589 | c.1116G>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039673 | c.1032G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039715 | c.990G>A | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039727 | c.978C>T | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039796 | c.909C>T | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039997 | c.708C>T | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040030 | c.675C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4040138 | c.567G>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.37 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040180 | c.525C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040243 | c.462C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040276 | c.427_429delTCCinsAGT | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040288 | c.417C>T | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040321 | c.384C>T | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040435 | c.270G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040444 | c.261C>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040456 | c.249C>T | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040486 | c.219G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040549 | c.154_156delTTGinsCTT | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040567 | c.138C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040573 | c.132T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040582 | c.123G>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040657 | c.48T>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040669 | c.36C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040695 | c.10C>A | synonymous_variant | 0.28 | pyrazinamide | |
panD | 4044138 | c.144T>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
panD | 4044141 | c.141C>G | synonymous_variant | 0.24 | pyrazinamide | |
panD | 4044150 | c.132A>G | synonymous_variant | 0.24 | pyrazinamide | |
panD | 4044159 | c.123C>T | synonymous_variant | 0.24 | pyrazinamide | |
panD | 4044162 | c.120A>G | synonymous_variant | 0.24 | pyrazinamide | |
panD | 4044165 | c.117G>C | synonymous_variant | 0.22 | pyrazinamide | |
panD | 4044177 | c.105C>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
panD | 4044188 | c.94T>C | synonymous_variant | 0.26 | pyrazinamide | |
panD | 4044195 | c.87T>C | synonymous_variant | 0.23 | pyrazinamide | |
panD | 4044201 | c.81C>G | synonymous_variant | 0.24 | pyrazinamide | |
panD | 4044225 | c.57C>T | synonymous_variant | 0.22 | pyrazinamide | |
panD | 4044228 | c.54C>T | synonymous_variant | 0.21 | pyrazinamide | |
panD | 4044231 | p.Cys17Gln | missense_variant | 0.21 | pyrazinamide | |
panD | 4044237 | c.45G>C | synonymous_variant | 0.21 | pyrazinamide | |
panD | 4044240 | c.42G>T | synonymous_variant | 0.21 | pyrazinamide | |
panD | 4044261 | c.21G>A | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
panD | 4044273 | c.9G>C | synonymous_variant | 0.19 | pyrazinamide | |
glpK | 4138418 | c.1338T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138424 | c.1332T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138429 | c.1327T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138451 | c.1305T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138472 | c.1284G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138478 | c.1278T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138502 | c.1254T>G | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139231 | c.525A>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139242 | c.514T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139243 | c.513A>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139255 | c.501G>A | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139258 | c.498C>A | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139261 | c.495C>G | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139270 | c.486C>G | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139273 | c.483A>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139276 | c.480T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139282 | c.474T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139285 | c.471A>G | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139306 | c.450C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139312 | c.444T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139321 | c.435T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139324 | c.432A>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139327 | c.429G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139339 | c.417G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4239125 | c.-738C>G | upstream_gene_variant | 0.21 | ethambutol | |
embC | 4239141 | c.-722G>A | upstream_gene_variant | 0.25 | ethambutol | Uncertain significance |
embC | 4239147 | c.-716T>C | upstream_gene_variant | 0.25 | ethambutol | |
embC | 4239156 | c.-707_-706delACinsTT | upstream_gene_variant | 0.27 | ethambutol | |
embC | 4239161 | c.-702A>G | upstream_gene_variant | 0.29 | ethambutol | |
embC | 4239173 | c.-690T>C | upstream_gene_variant | 0.29 | ethambutol | |
embC | 4239176 | c.-687C>G | upstream_gene_variant | 0.29 | ethambutol | |
embC | 4239179 | c.-684G>A | upstream_gene_variant | 0.3 | ethambutol | |
embC | 4239189 | c.-674C>T | upstream_gene_variant | 0.28 | ethambutol | |
embC | 4239209 | c.-654G>C | upstream_gene_variant | 0.28 | ethambutol | |
embC | 4239215 | c.-648T>G | upstream_gene_variant | 0.23 | ethambutol | |
embC | 4239336 | c.-527T>C | upstream_gene_variant | 0.2 | ethambutol | |
embC | 4239341 | c.-522G>C | upstream_gene_variant | 0.25 | ethambutol | |
embC | 4239378 | c.-485T>C | upstream_gene_variant | 0.28 | ethambutol | |
embC | 4239401 | c.-462A>C | upstream_gene_variant | 0.25 | ethambutol | |
embC | 4239407 | c.-456C>G | upstream_gene_variant | 0.21 | ethambutol | |
embC | 4240717 | c.855T>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embC | 4240741 | c.879C>T | synonymous_variant | 0.29 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.42 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.39 | ethambutol | |
embC | 4240811 | p.Phe317Leu | missense_variant | 0.33 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.32 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.28 | ethambutol | |
embC | 4240837 | c.975C>G | synonymous_variant | 0.33 | ethambutol | |
embC | 4240859 | p.Leu333Ile | missense_variant | 0.31 | ethambutol | |
embC | 4240867 | c.1005T>G | synonymous_variant | 0.28 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.3 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4240918 | c.1056G>C | synonymous_variant | 0.23 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.24 | ethambutol | |
embC | 4240927 | c.1065C>T | synonymous_variant | 0.24 | ethambutol | |
embC | 4241059 | c.1197G>A | synonymous_variant | 0.26 | ethambutol | |
embC | 4241086 | c.1224G>C | synonymous_variant | 0.32 | ethambutol | |
embC | 4241101 | c.1239G>C | synonymous_variant | 0.34 | ethambutol | |
embC | 4241121 | p.Ser420Asn | missense_variant | 0.32 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embC | 4241551 | c.1689A>C | synonymous_variant | 0.18 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.23 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.28 | ethambutol | |
embC | 4241587 | c.1725C>G | synonymous_variant | 0.3 | ethambutol | |
embC | 4241614 | c.1752A>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241617 | c.1755G>A | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
embC | 4241623 | c.1761C>A | synonymous_variant | 0.2 | ethambutol | |
embC | 4241626 | c.1764T>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4241635 | c.1773G>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4242375 | p.Arg838Gln | missense_variant | 0.38 | ethambutol | Uncertain significance |
embA | 4242391 | c.-842G>T | upstream_gene_variant | 0.41 | ethambutol | |
embA | 4242400 | c.-833C>G | upstream_gene_variant | 0.43 | ethambutol | |
embC | 4242402 | p.Arg847His | missense_variant | 0.44 | ethambutol | Uncertain significance |
embA | 4242406 | c.-827A>T | upstream_gene_variant | 0.46 | ethambutol | |
embA | 4242427 | c.-806A>G | upstream_gene_variant | 0.38 | ethambutol | |
embC | 4242428 | p.Ala856Pro | missense_variant | 0.38 | ethambutol | |
embC | 4242434 | p.Val858Ile | missense_variant | 0.36 | ethambutol | |
embA | 4242448 | c.-785C>G | upstream_gene_variant | 0.26 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4242805 | c.-428G>A | upstream_gene_variant | 0.23 | ethambutol | |
embA | 4242826 | c.-407G>C | upstream_gene_variant | 0.25 | ethambutol | |
embA | 4242827 | c.-406C>T | upstream_gene_variant | 0.24 | ethambutol | |
embA | 4242832 | c.-401A>G | upstream_gene_variant | 0.27 | ethambutol | |
embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.27 | ethambutol | |
embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.26 | ethambutol | |
embC | 4242847 | c.2985C>G | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embA | 4242853 | c.-380C>T | upstream_gene_variant | 0.27 | ethambutol | |
embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.32 | ethambutol | |
embA | 4242895 | c.-338C>T | upstream_gene_variant | 0.32 | ethambutol | |
embC | 4242904 | c.3042C>T | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
embA | 4242910 | c.-323C>T | upstream_gene_variant | 0.22 | ethambutol | |
embA | 4242919 | c.-314A>G | upstream_gene_variant | 0.2 | ethambutol | |
embA | 4242925 | c.-308C>T | upstream_gene_variant | 0.18 | ethambutol | |
embC | 4242928 | c.3066A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embA | 4243460 | c.228C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4244885 | c.1653A>G | synonymous_variant | 0.36 | ethambutol | |
embA | 4244886 | c.1654C>T | synonymous_variant | 0.36 | ethambutol | |
embA | 4244897 | c.1665T>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
embA | 4244900 | c.1668G>C | synonymous_variant | 0.39 | ethambutol | |
embA | 4244904 | p.Val558Leu | missense_variant | 0.36 | ethambutol | Uncertain significance |
embA | 4244909 | c.1677C>G | synonymous_variant | 0.32 | ethambutol | |
embA | 4244916 | c.1684C>T | synonymous_variant | 0.3 | ethambutol | |
embA | 4244921 | c.1689C>G | synonymous_variant | 0.29 | ethambutol | |
embA | 4245093 | p.Ile621Val | missense_variant | 0.17 | ethambutol | Uncertain significance |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.27 | ethambutol | |
embA | 4245136 | p.Tyr635Phe | missense_variant | 0.37 | ethambutol | |
embA | 4245149 | c.1917C>A | synonymous_variant | 0.42 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.41 | ethambutol | |
embA | 4245174 | p.Ser648Thr | missense_variant | 0.43 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.42 | ethambutol | |
embA | 4245186 | p.Thr652Ala | missense_variant | 0.4 | ethambutol | |
embA | 4245198 | p.Leu656Ala | missense_variant | 0.24 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4245713 | c.-801G>C | upstream_gene_variant | 0.21 | ethambutol | |
embB | 4245725 | c.-789A>C | upstream_gene_variant | 0.19 | ethambutol | |
embB | 4245726 | c.-788_-786delTTGinsCTC | upstream_gene_variant | 0.19 | ethambutol | |
embB | 4245737 | c.-777A>C | upstream_gene_variant | 0.19 | ethambutol | |
embB | 4245740 | c.-774T>C | upstream_gene_variant | 0.21 | ethambutol | |
embB | 4247371 | c.858C>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4247380 | c.867C>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4247386 | c.873T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4247389 | c.876C>G | synonymous_variant | 0.19 | ethambutol | |
embB | 4247395 | c.882C>A | synonymous_variant | 0.24 | ethambutol | |
embB | 4247401 | c.888T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
embB | 4247446 | c.933C>T | synonymous_variant | 0.26 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4247494 | c.981G>A | synonymous_variant | 0.27 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4247500 | c.987C>G | synonymous_variant | 0.28 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.34 | ethambutol | |
embB | 4247519 | c.1006C>T | synonymous_variant | 0.35 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.27 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 0.23 | ethambutol | |
embB | 4247572 | c.1059A>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247576 | c.1063C>T | synonymous_variant | 0.2 | ethambutol | |
embB | 4247579 | p.Ala356Ile | missense_variant | 0.2 | ethambutol | |
embB | 4247590 | c.1077A>G | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
embB | 4247972 | p.Thr487Phe | missense_variant | 0.32 | ethambutol | |
embB | 4247977 | c.1464C>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4247983 | c.1470G>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4247992 | c.1479G>A | synonymous_variant | 0.39 | ethambutol | Not assoc w R - Interim |
embB | 4248007 | c.1494C>G | synonymous_variant | 0.49 | ethambutol | |
embB | 4248035 | p.Val508Ile | missense_variant | 0.57 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.59 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Asp | missense_variant | 0.57 | ethambutol | |
embB | 4248055 | c.1542G>C | synonymous_variant | 0.52 | ethambutol | |
embB | 4248064 | c.1551G>C | synonymous_variant | 0.41 | ethambutol | Not assoc w R - Interim |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.4 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.36 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.35 | ethambutol | |
embB | 4248118 | c.1605T>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4248173 | p.Val554Leu | missense_variant | 0.22 | ethambutol | |
embB | 4248199 | c.1686A>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.18 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.19 | ethambutol | Uncertain significance |
embB | 4248211 | c.1698G>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248217 | c.1704C>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4248220 | c.1707A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embB | 4248226 | c.1713G>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248232 | c.1719G>A | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embB | 4248233 | c.1720C>T | synonymous_variant | 0.22 | ethambutol | |
embB | 4248241 | c.1728C>T | synonymous_variant | 0.23 | ethambutol | |
embB | 4248277 | c.1764G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4248280 | c.1767C>G | synonymous_variant | 0.26 | ethambutol | |
embB | 4248316 | c.1803C>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.32 | ethambutol | |
embB | 4248322 | c.1809G>C | synonymous_variant | 0.33 | ethambutol | |
embB | 4248328 | c.1815G>A | synonymous_variant | 0.31 | ethambutol | |
embB | 4248337 | c.1824G>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4249343 | p.Val944Ile | missense_variant | 0.32 | ethambutol | |
embB | 4249351 | c.2838C>G | synonymous_variant | 0.3 | ethambutol | |
embB | 4249354 | c.2841G>A | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
embB | 4249369 | c.2856T>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4249375 | c.2862G>C | synonymous_variant | 0.38 | ethambutol | |
embB | 4249381 | c.2868A>G | synonymous_variant | 0.38 | ethambutol | |
embB | 4249382 | p.Pro957Ala | missense_variant | 0.38 | ethambutol | |
embB | 4249387 | p.Glu958Asp | missense_variant | 0.38 | ethambutol | |
embB | 4249417 | c.2904A>G | synonymous_variant | 0.45 | ethambutol | |
embB | 4249423 | p.Asp970Glu | missense_variant | 0.44 | ethambutol | Uncertain significance |
embB | 4249432 | c.2919A>G | synonymous_variant | 0.4 | ethambutol | |
embB | 4249433 | c.2920C>T | synonymous_variant | 0.43 | ethambutol | |
embB | 4249441 | c.2928A>G | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
embB | 4249444 | c.2931T>C | synonymous_variant | 0.39 | ethambutol | |
embB | 4249447 | c.2934G>C | synonymous_variant | 0.4 | ethambutol | |
embB | 4249469 | p.Leu986Met | missense_variant | 0.39 | ethambutol | |
embB | 4249486 | c.2973T>G | synonymous_variant | 0.28 | ethambutol | |
embB | 4249487 | c.2974T>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4249492 | c.2979C>A | synonymous_variant | 0.3 | ethambutol | |
aftB | 4267622 | c.1213_1215delTCGinsAGC | synonymous_variant | 0.18 | ethambutol | |
aftB | 4267625 | c.1212T>C | synonymous_variant | 0.17 | ethambutol | |
aftB | 4267634 | p.Arg401His | missense_variant | 0.19 | ethambutol | |
aftB | 4267647 | p.Asp397Cys | missense_variant | 0.82 | ethambutol | |
aftB | 4267655 | c.1182C>G | synonymous_variant | 0.19 | ethambutol | |
aftB | 4268096 | c.741C>T | synonymous_variant | 0.23 | ethambutol | |
aftB | 4268099 | c.738G>T | synonymous_variant | 0.24 | ethambutol | |
aftB | 4268105 | c.732T>C | synonymous_variant | 0.23 | ethambutol | |
aftB | 4268120 | c.717C>G | synonymous_variant | 0.24 | ethambutol | |
aftB | 4268123 | p.Ser238Gly | missense_variant | 0.25 | ethambutol | |
aftB | 4268126 | c.711G>C | synonymous_variant | 0.25 | ethambutol | |
aftB | 4268129 | c.708T>G | synonymous_variant | 0.25 | ethambutol | |
aftB | 4268138 | c.699A>C | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
aftB | 4268144 | c.693T>C | synonymous_variant | 0.26 | ethambutol | |
ubiA | 4269131 | p.Leu235Met | missense_variant | 0.19 | ethambutol | Uncertain significance |
aftB | 4269138 | c.-302C>T | upstream_gene_variant | 0.24 | ethambutol | |
ubiA | 4269144 | c.690C>G | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
ubiA | 4269152 | p.Ala228Ser | missense_variant | 0.24 | ethambutol | Uncertain significance |
aftB | 4269153 | c.-317C>G | upstream_gene_variant | 0.24 | ethambutol | |
aftB | 4269156 | c.-320C>G | upstream_gene_variant | 0.24 | ethambutol | |
aftB | 4269164 | c.-328T>C | upstream_gene_variant | 0.27 | ethambutol | |
ubiA | 4269177 | c.657G>A | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
aftB | 4269183 | c.-347T>C | upstream_gene_variant | 0.35 | ethambutol | |
aftB | 4269210 | c.-374G>A | upstream_gene_variant | 0.39 | ethambutol | |
ubiA | 4269222 | c.612T>G | synonymous_variant | 0.37 | ethambutol | Not assoc w R - Interim |
aftB | 4269225 | c.-389C>A | upstream_gene_variant | 0.36 | ethambutol | |
aftB | 4269234 | c.-398A>G | upstream_gene_variant | 0.33 | ethambutol | |
aftB | 4269242 | c.-406C>T | upstream_gene_variant | 0.31 | ethambutol | |
ubiA | 4269243 | p.His197Gln | missense_variant | 0.31 | ethambutol | |
aftB | 4269248 | c.-412C>T | upstream_gene_variant | 0.32 | ethambutol | |
aftB | 4269252 | c.-416C>G | upstream_gene_variant | 0.31 | ethambutol | |
aftB | 4269267 | c.-431C>G | upstream_gene_variant | 0.24 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |