TB-Profiler result

Run: SRR1180172
Summary

Run ID: SRR1180172

Sample name:

Date: 2024-10-05T07:34:12.231631

Number of reads: 1635197

Percentage reads mapped: 54.92

Median coverage: 36.0

Strain: lineage2.2.1

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.07
lineage2 East-Asian RD105 0.98
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 0.95
lineage2.2 East-Asian (Beijing) RD105;RD207 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Met482Ile Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embB 4247448 p.His312Arg missense_variant 0.27 ethambutol Mutation from literature
embB 4247959 p.Met482Ile missense_variant 0.23 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 540 c.540C>T synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 549 c.549C>T synonymous_variant 0.21 isoniazid
dnaA 552 c.552G>C synonymous_variant 0.22 isoniazid
dnaA 558 c.558G>C synonymous_variant 0.22 isoniazid
dnaA 567 c.567C>G synonymous_variant 0.22 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.22 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.21 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 0.24 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.21 isoniazid
dnaA 594 c.594C>G synonymous_variant 0.22 isoniazid
dnaA 597 c.597C>T synonymous_variant 0.2 isoniazid
dnaA 600 c.600T>C synonymous_variant 0.21 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.18 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.25 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.24 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.24 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.24 isoniazid
dnaA 930 c.930G>A synonymous_variant 0.23 isoniazid
dnaA 939 c.939C>T synonymous_variant 0.25 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.25 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.24 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.18 isoniazid
dnaA 1053 c.1053C>T synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 1077 c.1077A>G synonymous_variant 0.38 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.31 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.29 isoniazid
dnaA 1107 c.1107C>T synonymous_variant 0.28 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.29 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>C synonymous_variant 0.35 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.3 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.28 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.28 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.22 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.21 isoniazid
dnaA 1180 c.1180C>T synonymous_variant 0.22 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 0.31 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.3 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.35 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.34 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.29 isoniazid
dnaA 1224 c.1224C>G synonymous_variant 0.29 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.35 isoniazid
dnaA 1239 c.1239G>A synonymous_variant 0.37 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.4 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.43 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.42 isoniazid
dnaA 1291 c.1291_1293delCTTinsTTA synonymous_variant 0.4 isoniazid
dnaA 1299 c.1299G>T synonymous_variant 0.42 isoniazid
dnaA 1317 c.1317A>C synonymous_variant 0.48 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 1329 c.1329A>G synonymous_variant 0.36 isoniazid
dnaA 1332 c.1332A>G synonymous_variant 0.34 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.38 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 0.33 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.33 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>G synonymous_variant 0.37 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 0.36 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.35 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.28 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.27 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.32 isoniazid
dnaA 1428 c.1428C>A synonymous_variant 0.33 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.33 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 0.31 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 0.3 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.29 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.28 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.24 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 0.19 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.2 isoniazid Not assoc w R - Interim
dnaA 1479 c.1479C>T synonymous_variant 0.2 isoniazid
gyrB 6151 c.912C>T synonymous_variant 0.17 levofloxacin
moxifloxacin
gyrB 6157 c.918C>T synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6355 c.-947G>A upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6362 c.-940_-938delTTGinsCTA upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6631 c.-671C>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6644 c.-658_-657delAGinsTC upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.3 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrB 6721 c.1482C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6730 c.-572A>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6781 c.-521C>T upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6835 c.-467C>T upstream_gene_variant 0.16 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.19 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.2 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>T upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6941 c.-361C>T upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7388 c.87C>A synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 7424 c.123G>A synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7427 c.126G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7625 c.324G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7793 c.492G>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 8096 c.795T>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8213 c.912C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.32 levofloxacin
moxifloxacin
gyrA 8252 c.951G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.36 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8321 c.1020C>T synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8337 c.1036_1038delCTAinsTTG synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.35 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.22 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8486 c.1185T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8492 c.1191G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8507 c.1206C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8528 c.1227G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8576 c.1275C>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8636 c.1335A>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 8664 c.1363C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8855 c.1554C>G synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>T synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8957 c.1656C>T synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8983 p.Cys561Ser missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>A synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>A synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 0.18 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.25 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.24 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.25 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9185 c.1884C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9192 c.1891C>T synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9203 c.1902G>A synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 490803 c.21T>A synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>T synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 490818 c.36C>T synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 490830 c.48A>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 490851 c.69A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 490854 c.72C>T synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 490857 c.75C>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 490869 c.87C>A synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491022 c.240C>G synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491058 c.276C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491064 c.282A>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 491112 c.330G>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.24 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491289 c.507C>T synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491290 p.Val170Ile missense_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.25 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491310 c.528C>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491316 c.534C>A synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491320 p.Ala180Gln missense_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491331 c.549G>A synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491538 c.756G>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fgd1 491623 p.Ala281Thr missense_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491637 c.855C>A synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 575746 c.399C>G synonymous_variant 0.28 isoniazid
ethionamide
mshA 575761 c.414C>T synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575821 c.474G>C synonymous_variant 0.3 isoniazid
ethionamide
mshA 575824 c.477T>A synonymous_variant 0.31 isoniazid
ethionamide
mshA 575851 c.504C>T synonymous_variant 0.35 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575860 c.513G>A synonymous_variant 0.37 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.37 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.46 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.46 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.46 isoniazid
ethionamide
mshA 575905 c.558G>C synonymous_variant 0.54 isoniazid
ethionamide
mshA 575907 p.Ala187Val missense_variant 0.47 isoniazid Not assoc w R
ethionamide Not assoc w R
mshA 575916 p.Asp190Ala missense_variant 0.49 isoniazid
ethionamide
mshA 575924 p.Gly193Ile missense_variant 0.43 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.34 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.32 isoniazid
ethionamide
mshA 575971 c.624C>T synonymous_variant 0.34 isoniazid
ethionamide
mshA 576193 c.846T>C synonymous_variant 0.19 isoniazid
ethionamide
mshA 576202 c.855T>G synonymous_variant 0.19 isoniazid
ethionamide
mshA 576205 c.858G>A synonymous_variant 0.18 isoniazid
ethionamide
mshA 576214 c.867G>A synonymous_variant 0.19 isoniazid
ethionamide
mshA 576220 c.873C>G synonymous_variant 0.2 isoniazid
ethionamide
mshA 576223 c.876G>C synonymous_variant 0.2 isoniazid
ethionamide
mshA 576233 p.Ile296Val missense_variant 0.2 isoniazid
ethionamide
mshA 576247 c.900A>C synonymous_variant 0.27 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 619615 c.-276C>T upstream_gene_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 619627 c.-264C>T upstream_gene_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>G upstream_gene_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 619647 c.-244T>C upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619669 c.-222G>C upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>G upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619681 c.-210G>C upstream_gene_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>T synonymous_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620625 p.Ile245Met missense_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657647 c.-179_-177delGTCinsATT upstream_gene_variant 0.16 ethionamide
Rv0565c 657689 c.-219A>C upstream_gene_variant 0.18 ethionamide
hadA 731753 c.-177A>T upstream_gene_variant 0.26 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.37 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.39 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.42 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.45 isoniazid
hadA 731825 c.-105G>C upstream_gene_variant 0.37 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.33 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.28 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.28 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.31 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 0.19 rifampicin Uncertain significance
nusG 734093 c.-161A>G upstream_gene_variant 0.2 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.21 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.18 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.19 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.18 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.23 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.24 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 0.22 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.22 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.26 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.37 rifampicin
nusG 734415 c.162C>T synonymous_variant 0.38 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.4 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.42 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.48 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.45 rifampicin
nusG 734457 c.204C>T synonymous_variant 0.43 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.41 rifampicin
nusG 734505 c.252G>A synonymous_variant 0.43 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.39 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.39 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.29 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.35 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
nusG 734847 c.594T>C synonymous_variant 0.36 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.36 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.36 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.37 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.38 rifampicin
nusG 734905 c.652C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
nusG 734910 c.657C>G synonymous_variant 0.26 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.25 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.19 rifampicin
nusG 734943 c.690G>C synonymous_variant 0.17 rifampicin
nusG 734946 c.693C>T synonymous_variant 0.17 rifampicin
nusG 734951 p.Gly233Ala missense_variant 0.17 rifampicin
mmaA3 738315 c.-166G>A upstream_gene_variant 0.26 isoniazid
mmaA3 738346 c.-198_-197delCTinsGC upstream_gene_variant 0.26 isoniazid
mmaA3 738348 c.-199G>C upstream_gene_variant 0.27 isoniazid
rpoB 760088 c.282C>G synonymous_variant 0.3 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.33 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.34 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.39 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 760145 c.339C>G synonymous_variant 0.45 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.29 rifampicin
rpoB 760307 c.501T>C synonymous_variant 0.19 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.22 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.3 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760356 p.Thr184Ser missense_variant 0.34 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.34 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.32 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.32 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760415 c.609C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.36 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.34 rifampicin Uncertain significance
rpoB 760533 p.Val243His missense_variant 0.29 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760556 c.750G>A synonymous_variant 0.36 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.35 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.35 rifampicin
rpoB 760598 c.792C>T synonymous_variant 0.32 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.26 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.23 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.22 rifampicin
rpoB 760754 c.948G>C synonymous_variant 0.22 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.22 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.22 rifampicin
rpoB 760763 c.957C>T synonymous_variant 0.2 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.21 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.22 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.24 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ser missense_variant 0.19 rifampicin
rpoB 760850 c.1044G>C synonymous_variant 0.18 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 0.29 rifampicin
rpoB 760877 c.1071G>T synonymous_variant 0.38 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.37 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.32 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.33 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.33 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.41 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.43 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.42 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.53 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.4 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.4 rifampicin
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.29 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 0.36 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 0.37 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>T synonymous_variant 0.36 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.36 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.42 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.46 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.47 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.41 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.39 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.37 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.43 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.38 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.38 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.37 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.33 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.31 rifampicin
rpoB 761465 c.1659G>T synonymous_variant 0.33 rifampicin
rpoB 761471 c.1665C>T synonymous_variant 0.32 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 0.31 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.29 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.33 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.37 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 0.42 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.42 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>T synonymous_variant 0.43 rifampicin
rpoB 761561 c.1755C>G synonymous_variant 0.48 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761582 c.1776G>A synonymous_variant 0.6 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.49 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.44 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.38 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.35 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.29 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.27 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.27 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.31 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.29 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.3 rifampicin
rpoB 761786 c.1980C>A synonymous_variant 0.33 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.32 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.38 rifampicin
rpoB 761819 c.2013G>A synonymous_variant 0.37 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.39 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.38 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.41 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.47 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 0.62 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.66 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.5 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.4 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.38 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.37 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.36 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.35 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.36 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 0.38 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761955 p.Ile717Val missense_variant 0.26 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.38 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.44 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762050 c.2244G>A synonymous_variant 0.47 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.44 rifampicin Uncertain significance
rpoB 762138 c.2332C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.47 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.55 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.41 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.36 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.38 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.3 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762347 c.2541T>C synonymous_variant 0.37 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 0.36 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.35 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 0.33 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.31 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.3 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.33 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.29 rifampicin
rpoC 762401 c.-969G>T upstream_gene_variant 0.29 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.41 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 762443 c.-927G>C upstream_gene_variant 0.36 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762507 p.Leu901Met missense_variant 0.33 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.32 rifampicin Uncertain significance
rpoC 762524 c.-846G>C upstream_gene_variant 0.3 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.25 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.24 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.24 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.21 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762788 c.2982G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.28 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.29 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 0.32 rifampicin Uncertain significance
rpoC 762800 c.-570C>A upstream_gene_variant 0.32 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 762824 c.-546C>T upstream_gene_variant 0.37 rifampicin
rpoC 762827 c.-543G>T upstream_gene_variant 0.38 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 762920 c.-450C>G upstream_gene_variant 0.48 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>A upstream_gene_variant 0.46 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763082 c.-288C>G upstream_gene_variant 0.49 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>A upstream_gene_variant 0.49 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.35 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 0.35 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.29 rifampicin
rpoC 763402 c.33C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.35 rifampicin
rpoC 763423 c.54G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.43 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>A synonymous_variant 0.57 rifampicin
rpoC 763573 c.204G>T synonymous_variant 0.59 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>A synonymous_variant 0.49 rifampicin
rpoC 763618 c.249C>T synonymous_variant 0.49 rifampicin
rpoC 763621 c.252C>G synonymous_variant 0.49 rifampicin
rpoC 763636 c.267T>G synonymous_variant 0.48 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763681 c.312C>A synonymous_variant 0.38 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.35 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.44 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.42 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.44 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.43 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.43 rifampicin
rpoC 763768 c.399C>T synonymous_variant 0.4 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.42 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.4 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.43 rifampicin
rpoC 763836 p.Ala156Val missense_variant 0.43 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.41 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.41 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.39 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.38 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.41 rifampicin
rpoC 763888 c.519G>T synonymous_variant 0.4 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.42 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.38 rifampicin
rpoC 763936 c.567C>G synonymous_variant 0.41 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.4 rifampicin
rpoC 763969 c.600C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.4 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.46 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.46 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.48 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764024 c.655T>C synonymous_variant 0.47 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.41 rifampicin
rpoC 764044 c.675T>G synonymous_variant 0.42 rifampicin
rpoC 764056 c.687G>T synonymous_variant 0.44 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.48 rifampicin
rpoC 764080 c.711C>T synonymous_variant 0.49 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.47 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 0.42 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 0.32 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 0.32 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.36 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764218 c.849C>T synonymous_variant 0.42 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.34 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>A synonymous_variant 0.37 rifampicin
rpoC 764260 c.891G>A synonymous_variant 0.4 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.38 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.42 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.42 rifampicin
rpoC 764339 c.970C>T synonymous_variant 0.48 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>T synonymous_variant 0.27 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.22 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.23 rifampicin
rpoC 764452 c.1083T>G synonymous_variant 0.23 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 0.25 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.24 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.47 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.42 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.47 rifampicin
rpoC 764578 c.1209C>G synonymous_variant 0.36 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.21 rifampicin
rpoC 764857 c.1488G>T synonymous_variant 0.32 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.32 rifampicin
rpoC 764887 c.1518G>A synonymous_variant 0.31 rifampicin
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.31 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.3 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.3 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 0.32 rifampicin
rpoC 764908 c.1539G>A synonymous_variant 0.33 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.22 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>T synonymous_variant 0.16 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.26 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.16 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 0.26 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.25 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 0.29 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 0.3 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 0.36 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.41 rifampicin Uncertain significance
rpoC 765404 c.2035C>T synonymous_variant 0.45 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.43 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.46 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>T synonymous_variant 0.42 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>A synonymous_variant 0.34 rifampicin
rpoC 765529 c.2160C>T synonymous_variant 0.31 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.26 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.29 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.32 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.33 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.34 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.36 rifampicin
rpoC 765592 c.2223C>T synonymous_variant 0.39 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.36 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765685 c.2316G>A synonymous_variant 0.3 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 0.48 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.47 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.42 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.43 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.36 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.41 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.41 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.4 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.37 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.57 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.57 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765907 c.2538G>A synonymous_variant 0.6 rifampicin
rpoC 765928 c.2559C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.57 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 0.44 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>A synonymous_variant 0.33 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.26 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.4 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.42 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.4 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.37 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.35 rifampicin
rpoC 766096 c.2727G>T synonymous_variant 0.39 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.41 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.39 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.38 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 0.38 rifampicin Uncertain significance
rpoC 766178 p.Ile937Val missense_variant 0.33 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.28 rifampicin
rpoC 766192 c.2823T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 766193 p.Gln942Glu missense_variant 0.21 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.24 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.24 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.24 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 0.3 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.27 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.32 rifampicin
rpoC 766333 c.2964G>C synonymous_variant 0.35 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.35 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.33 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.36 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.38 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.42 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.42 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.44 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.48 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.55 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.54 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.6 rifampicin
rpoC 766492 c.3123T>A synonymous_variant 0.6 rifampicin
rpoC 766500 p.Ala1044Val missense_variant 0.37 rifampicin Uncertain significance
rpoC 766522 c.3153C>G synonymous_variant 0.51 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.52 rifampicin
rpoC 766540 c.3171C>T synonymous_variant 0.52 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.54 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.6 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 0.57 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.56 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.57 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.58 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.59 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.57 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.57 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 0.6 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.57 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.57 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.56 rifampicin
rpoC 766801 c.3432C>A synonymous_variant 0.55 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.39 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.3 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 0.34 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.4 rifampicin
rpoC 767044 c.3675G>A synonymous_variant 0.46 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.49 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.52 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 0.46 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 0.44 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.43 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.41 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.46 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.46 rifampicin
rpoC 767275 c.3906T>A synonymous_variant 0.37 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.35 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.35 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775981 p.Leu834Met missense_variant 0.3 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.17 bedaquiline
clofazimine
mmpL5 776030 c.2451G>A synonymous_variant 0.19 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776182 p.Asp767Asn missense_variant 1.0 bedaquiline Not assoc w R
clofazimine Not assoc w R
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0 bedaquiline
clofazimine
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.33 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.32 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.31 streptomycin
rpsL 781622 c.63C>G synonymous_variant 0.37 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.36 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.41 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.41 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.34 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.37 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.33 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.33 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.32 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.33 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.37 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.43 streptomycin
rpsL 781820 c.261G>T synonymous_variant 0.48 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.49 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.45 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.47 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.42 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.4 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.44 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.33 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.32 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.31 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.17 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.34 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.38 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.37 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.36 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.35 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.3 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.3 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.24 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.27 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.33 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.3 linezolid
rplC 800715 c.-94_-92delATCinsCTT upstream_gene_variant 0.31 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.32 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 0.31 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.29 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.21 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.21 linezolid
rplC 801123 c.315C>T synonymous_variant 0.18 linezolid Not assoc w R - Interim
rplC 801132 c.324T>C synonymous_variant 0.24 linezolid
rplC 801136 p.Ser110Ala missense_variant 0.25 linezolid
rplC 801141 c.333C>T synonymous_variant 0.26 linezolid
rplC 801147 c.339T>C synonymous_variant 0.26 linezolid
rplC 801153 c.345G>C synonymous_variant 0.26 linezolid
rplC 801156 c.348T>G synonymous_variant 0.28 linezolid
rplC 801171 c.363A>G synonymous_variant 0.36 linezolid
rplC 801174 c.366T>C synonymous_variant 0.36 linezolid
rplC 801195 c.387G>C synonymous_variant 0.38 linezolid
rplC 801207 c.399C>T synonymous_variant 0.39 linezolid
rplC 801210 c.402T>C synonymous_variant 0.38 linezolid
rplC 801255 c.447C>T synonymous_variant 0.25 linezolid
rplC 801300 c.492C>G synonymous_variant 0.2 linezolid
rplC 801309 c.501C>G synonymous_variant 0.2 linezolid
rplC 801312 c.504G>C synonymous_variant 0.2 linezolid
rplC 801321 c.513C>T synonymous_variant 0.25 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.24 linezolid
rplC 801339 c.531T>G synonymous_variant 0.23 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.24 linezolid
rplC 801348 c.540T>G synonymous_variant 0.21 linezolid
rplC 801349 p.Leu181Val missense_variant 0.21 linezolid
rplC 801357 c.549T>C synonymous_variant 0.24 linezolid
rplC 801378 c.570C>T synonymous_variant 0.25 linezolid
rplC 801402 c.594T>C synonymous_variant 0.2 linezolid
rplC 801405 c.597T>C synonymous_variant 0.21 linezolid
rplC 801408 c.600C>A synonymous_variant 0.2 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
fbiC 1303480 p.Gln184Glu missense_variant 0.17 pretomanid
delamanid
clofazimine
fbiC 1303492 c.562T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303506 c.576C>T synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1303537 p.Arg203Leu missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303542 c.612C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1303593 c.663G>A synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303596 c.666G>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>A synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303716 c.786C>T synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303722 c.792C>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303750 c.820_822delTTAinsCTG synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303755 c.825T>C synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303779 c.849G>A synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>T synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303788 c.858T>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303794 c.864A>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304619 c.1689G>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>T synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304754 c.1824G>A synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1304796 c.1866G>A synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304823 c.1893C>T synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.49 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304896 c.1966C>T synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304915 p.Asp662Gly missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304970 c.2040G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1304988 c.2058G>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1305144 c.2214G>A synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305150 c.2220C>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1305173 p.Asn748Ser missense_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305177 c.2247A>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1305181 c.2251T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 0.34 pretomanid
delamanid
clofazimine
sigE 1364667 c.255T>C synonymous_variant 0.24 pyrazinamide
sigE 1364671 c.259C>T synonymous_variant 0.24 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.25 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.31 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.23 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.34 pyrazinamide
sigE 1364931 c.519C>G synonymous_variant 0.35 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.3 pyrazinamide
sigE 1364955 c.543G>C synonymous_variant 0.31 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.31 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.32 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.34 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.34 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.36 pyrazinamide
sigE 1365030 c.618C>T synonymous_variant 0.37 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.36 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.4 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.41 pyrazinamide
sigE 1365063 c.651A>T synonymous_variant 0.34 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.32 pyrazinamide
sigE 1365078 c.666C>G synonymous_variant 0.32 pyrazinamide
sigE 1365081 c.669G>T synonymous_variant 0.32 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.31 pyrazinamide
sigE 1365087 c.675A>C synonymous_variant 0.31 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.3 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.26 pyrazinamide
sigE 1365111 c.699C>T synonymous_variant 0.2 pyrazinamide
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0 streptomycin Uncertain significance
pyrazinamide Uncertain significance
isoniazid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.41 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.44 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.44 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472029 n.185_188delGGGA non_coding_transcript_exon_variant 0.21 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.21 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.36 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.21 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.21 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.57 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.27 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.28 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.39 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.35 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.4 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.39 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1473987 n.330G>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.38 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474002 n.345G>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474007 n.350A>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474156 n.499G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474291 n.635_644delTTCCTCTCCG non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474306 n.651_655delGGTGG non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475446 n.1789G>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.4 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475759 n.2102_2106delCCCGCinsTCGT non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.4 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476104 n.2448delG non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>G non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476595 n.2938C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476602 n.2945G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.47 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
inhA 1673490 c.-712A>G upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673494 c.-708C>T upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673499 c.-703T>G upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673505 c.-697A>C upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1673523 c.-679G>T upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673535 c.-667A>C upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673721 c.-481C>T upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673727 c.-475C>T upstream_gene_variant 0.22 isoniazid Uncertain significance
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 0.23 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.23 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.23 isoniazid
ethionamide
inhA 1673758 c.-444A>G upstream_gene_variant 0.22 isoniazid
ethionamide
inhA 1674810 c.609C>G synonymous_variant 0.19 isoniazid
ethionamide
inhA 1674813 c.612C>T synonymous_variant 0.18 isoniazid
ethionamide
inhA 1674816 c.615T>C synonymous_variant 0.19 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674819 c.618G>T synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674840 c.639C>T synonymous_variant 0.25 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.26 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.23 isoniazid
ethionamide
inhA 1674927 c.726G>A synonymous_variant 0.27 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674939 c.738G>T synonymous_variant 0.26 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.26 isoniazid
ethionamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.17 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.34 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.35 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.37 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.38 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.36 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833749 p.Ile70Leu missense_variant 0.57 pyrazinamide Not assoc w R
rpsA 1833760 c.219C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
rpsA 1833782 p.Ser81Thr missense_variant 0.45 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.43 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.43 pyrazinamide
rpsA 1833799 c.258C>A synonymous_variant 0.4 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.4 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 0.39 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.39 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 0.4 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.38 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.38 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.37 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.35 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.32 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.29 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.36 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.38 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833934 c.393C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
rpsA 1833949 c.408T>C synonymous_variant 0.4 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.41 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.45 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.27 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.27 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834234 c.693G>C synonymous_variant 0.33 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.33 pyrazinamide
rpsA 1834255 c.714C>G synonymous_variant 0.33 pyrazinamide
rpsA 1834258 c.717G>A synonymous_variant 0.32 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTTG synonymous_variant 0.33 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.32 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.33 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.33 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.36 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.35 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.35 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.34 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.4 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.42 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.42 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.5 pyrazinamide
rpsA 1834517 c.976C>T synonymous_variant 0.5 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 0.53 pyrazinamide Uncertain significance
rpsA 1834609 c.1068T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834615 c.1074C>T synonymous_variant 0.62 pyrazinamide
rpsA 1834624 c.1083G>A synonymous_variant 0.64 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.63 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.56 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834669 c.1128G>C synonymous_variant 0.45 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.26 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.26 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.23 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 0.19 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.2 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.26 linezolid
tsnR 1853468 c.-138C>T upstream_gene_variant 0.28 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.28 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.28 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.28 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.24 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2063541 c.1188A>G synonymous_variant 0.24 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063550 c.1179C>G synonymous_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063574 c.1155C>G synonymous_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063583 c.1146G>C synonymous_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063598 c.1131T>C synonymous_variant 0.35 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064975 c.-247G>C upstream_gene_variant 0.27 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064981 c.-253G>C upstream_gene_variant 0.28 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.27 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064996 c.-268G>A upstream_gene_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101912 c.1131G>A synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2101960 c.1083A>G synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2101964 p.Glu360Ala missense_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2101966 c.1077T>A synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2101972 c.1071G>C synonymous_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2101980 p.Asn355Asp missense_variant 0.43 isoniazid
delamanid
ethionamide
ndh 2101987 c.1056C>G synonymous_variant 0.44 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>C synonymous_variant 0.44 isoniazid
delamanid
ethionamide
ndh 2101999 c.1044G>A synonymous_variant 0.41 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102020 c.1023A>G synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102023 c.1020G>C synonymous_variant 0.39 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102026 c.1017G>T synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102035 c.1008C>G synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102047 c.996G>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102050 c.993T>A synonymous_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2102059 c.984T>A synonymous_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2102065 c.978G>C synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2102068 c.975T>G synonymous_variant 0.25 isoniazid
delamanid
ethionamide
ndh 2102686 c.357G>C synonymous_variant 0.24 isoniazid
delamanid
ethionamide
ndh 2102707 c.336C>T synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102710 c.333C>T synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102713 c.330C>T synonymous_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102718 p.Gln109Glu missense_variant 0.27 isoniazid
delamanid
ethionamide
ndh 2102722 c.321C>G synonymous_variant 0.27 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102731 c.312C>G synonymous_variant 0.27 isoniazid
delamanid
ethionamide
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517941 c.-174C>G upstream_gene_variant 0.37 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.32 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.29 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.21 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.18 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.21 isoniazid
kasA 2518567 c.453G>T synonymous_variant 0.18 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.23 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.23 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.22 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.26 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.28 isoniazid
kasA 2518687 p.Asp191Glu missense_variant 0.28 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.35 isoniazid
kasA 2518717 c.603C>G synonymous_variant 0.33 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.31 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.3 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.31 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.3 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.28 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.28 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.3 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.33 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.32 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.28 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.28 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.31 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.32 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.24 isoniazid
kasA 2518907 c.793T>C synonymous_variant 0.25 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.22 isoniazid
kasA 2519104 c.990T>A synonymous_variant 0.18 isoniazid
kasA 2519119 c.1005G>C synonymous_variant 0.18 isoniazid
kasA 2519146 c.1032C>G synonymous_variant 0.27 isoniazid
kasA 2519152 c.1038G>T synonymous_variant 0.27 isoniazid
kasA 2519161 c.1047G>A synonymous_variant 0.31 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.31 isoniazid
kasA 2519188 c.1074G>A synonymous_variant 0.38 isoniazid
kasA 2519197 c.1083G>C synonymous_variant 0.31 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 0.3 isoniazid
kasA 2519206 c.1092C>T synonymous_variant 0.31 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.24 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 0.22 isoniazid
eis 2714526 c.805_806delAC frameshift_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
folC 2746584 c.1015T>C synonymous_variant 0.22 para-aminosalicylic_acid
folC 2746591 c.1008C>G synonymous_variant 0.2 para-aminosalicylic_acid
folC 2746597 c.1002C>G synonymous_variant 0.2 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2746612 c.987C>T synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 0.31 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 0.3 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.34 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.32 para-aminosalicylic_acid
folC 2746975 c.624T>C synonymous_variant 0.2 para-aminosalicylic_acid
folC 2746978 p.Ala207Glu missense_variant 0.2 para-aminosalicylic_acid
folC 2746990 p.Asp203Glu missense_variant 0.24 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 0.19 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 0.19 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.23 para-aminosalicylic_acid
folC 2747314 c.285A>T synonymous_variant 0.21 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.19 para-aminosalicylic_acid
Rv2477c 2782822 c.1221G>C synonymous_variant 0.18 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.17 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782831 c.1212G>A synonymous_variant 0.19 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782846 p.Arg399Lys missense_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 c.1182T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782868 p.Ala392Ser missense_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782885 c.1158G>C synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 0.19 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.23 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783164 c.879G>A synonymous_variant 0.23 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783167 c.876G>A synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.25 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783338 c.705C>T synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Ala missense_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 0.39 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783449 c.594C>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.34 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783548 c.495T>A synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.4 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783566 c.477C>T synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783650 c.393C>T synonymous_variant 0.52 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783659 c.384A>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783791 c.252C>T synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783842 c.201C>T synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.57 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>A synonymous_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783967 c.76T>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.37 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784396 c.-354A>T upstream_gene_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.27 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2859825 p.Ala198Ser missense_variant 0.22 bedaquiline
clofazimine
pepQ 2859828 c.591G>A synonymous_variant 0.23 bedaquiline
clofazimine
pepQ 2859834 c.585T>C synonymous_variant 0.23 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
Rv2752c 3065016 c.1176C>T synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065022 c.1170G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065046 c.1146G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065052 c.1140G>A synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065067 c.1125C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065073 c.1119C>G synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065106 c.1086C>G synonymous_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065430 c.762A>T synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065463 c.729T>C synonymous_variant 0.16 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065475 c.717C>T synonymous_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065614 p.Asp193Gly missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065634 c.558G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065637 c.555A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065711 p.Gly161Ser missense_variant 0.89 levofloxacin Uncertain significance
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
Rv2752c 3065928 c.264G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065947 p.Gly82Ala missense_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065949 c.243C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065957 c.235T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065958 c.234G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.29 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066002 p.Met64Leu missense_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066006 c.186G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066084 c.108C>T synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066087 c.105A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3066118 p.Asn25Gly missense_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066126 c.66C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066129 c.63G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066135 c.57C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066138 c.54C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066420 c.-229C>G upstream_gene_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066435 c.-244T>A upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066456 c.-265A>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066465 c.-276_-274delGGGinsAGC upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066468 c.-277C>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066471 c.-280A>C upstream_gene_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066474 c.-283G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066480 c.-291_-289delGCCinsTCT upstream_gene_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066504 c.-313C>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066596 c.-405C>T upstream_gene_variant 0.18 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066597 c.-406C>T upstream_gene_variant 0.17 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066636 c.-445G>A upstream_gene_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066672 c.-481G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066676 c.-485C>T upstream_gene_variant 0.44 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066687 c.-496G>A upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066699 c.-508C>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066707 c.-516A>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066714 c.-523G>A upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066717 c.-526C>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066720 c.-529G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067316 c.630A>G synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067360 p.Ile196Val missense_variant 0.33 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067382 c.564C>T synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067418 c.528C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067670 c.276G>A synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.28 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073932 c.540C>T synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3073983 c.489C>T synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3074046 c.426G>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.35 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.33 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3074089 p.Ile128Asn missense_variant 0.19 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 0.19 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3074133 c.339C>T synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.32 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3074163 p.Ala103Thr missense_variant 0.31 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3074196 c.276G>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074199 c.273G>A synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.4 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074220 c.252A>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074244 c.228A>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3074252 p.Glu74Gln missense_variant 0.26 para-aminosalicylic_acid
thyA 3074253 p.His73Gln missense_variant 0.26 para-aminosalicylic_acid
thyA 3074256 c.216G>A synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.19 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.19 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
fbiD 3339333 c.216G>A synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
lpqB 3624674 c.237C>T synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624680 c.231T>C synonymous_variant 0.19 rifampicin
bedaquiline
lpqB 3624686 p.Glu75Gln missense_variant 0.2 rifampicin
bedaquiline
lpqB 3624701 c.210T>A synonymous_variant 0.28 rifampicin
bedaquiline
lpqB 3624713 c.198C>T synonymous_variant 0.28 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.32 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 0.31 rifampicin
bedaquiline
lpqB 3624760 c.151C>T synonymous_variant 0.31 rifampicin
bedaquiline
lpqB 3624776 c.135T>C synonymous_variant 0.32 rifampicin
bedaquiline
lpqB 3624779 c.132G>C synonymous_variant 0.31 rifampicin
bedaquiline
lpqB 3624783 p.Ser43Thr missense_variant 0.31 rifampicin
bedaquiline
lpqB 3624788 c.123A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3625095 p.Glu507Gln missense_variant 0.19 rifampicin
bedaquiline
lpqB 3625096 c.-186C>T upstream_gene_variant 0.18 rifampicin
bedaquiline
lpqB 3625102 c.-192A>G upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625153 c.-243C>T upstream_gene_variant 0.16 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.21 rifampicin
bedaquiline
lpqB 3625174 c.-264C>A upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625183 c.-273G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625186 c.-276T>G upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.33 rifampicin
bedaquiline
lpqB 3625218 c.-308C>A upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625240 c.-330T>C upstream_gene_variant 0.32 rifampicin
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 0.32 rifampicin
bedaquiline
lpqB 3625255 c.-345T>G upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3625261 c.1353C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.21 rifampicin
bedaquiline
lpqB 3625669 c.-759G>A upstream_gene_variant 0.25 rifampicin
bedaquiline
lpqB 3625693 c.-783G>T upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrB 3625708 c.906C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.36 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625804 c.-896_-894delAGGinsCGA upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625822 c.-912C>T upstream_gene_variant 0.3 rifampicin
bedaquiline
lpqB 3625828 c.-918G>A upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625846 c.-936G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625860 p.Ala252Ser missense_variant 0.27 rifampicin
bedaquiline
mtrB 3625864 c.750T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625888 c.-978G>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3626562 p.Pro18Ser missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3626684 c.-71G>T upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626702 c.-91_-89delCTGinsTTA upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626819 c.-206G>A upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.25 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrB 3627113 c.-500C>T upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrA 3627175 c.175C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627185 c.-574_-572delTTGinsCTT upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3627190 c.160T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627197 c.-584T>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627233 c.-620T>G upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3627239 c.111C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrA 3627242 c.108C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.27 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrB 3627278 c.-665G>T upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3627287 c.-674C>G upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3627296 c.-683T>G upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTC upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.29 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 0.21 rifampicin
bedaquiline
rpoA 3877527 c.981C>G synonymous_variant 0.19 rifampicin
rpoA 3877542 c.966C>T synonymous_variant 0.28 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.52 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.51 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.35 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.26 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 0.43 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 0.42 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.43 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.4 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.37 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.36 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.37 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.37 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.43 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.4 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>A synonymous_variant 0.4 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.37 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.37 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.37 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.37 rifampicin
rpoA 3878043 c.465G>C synonymous_variant 0.45 rifampicin
rpoA 3878049 c.459G>C synonymous_variant 0.45 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.48 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.45 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.44 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 0.4 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.38 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 0.45 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.5 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.52 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.58 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.42 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 0.26 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.22 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.3 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 0.27 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.29 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878355 c.153C>G synonymous_variant 0.31 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.35 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3878406 c.102G>T synonymous_variant 0.55 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.56 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.52 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.54 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.47 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.52 rifampicin
rpoA 3878471 p.Val13Ile missense_variant 0.43 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.39 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.35 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.23 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.37 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.38 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.37 rifampicin
rpoA 3878837 c.-331_-330delAAinsGG upstream_gene_variant 0.34 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.4 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.41 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 0.36 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.38 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.39 rifampicin Uncertain significance
rpoA 3878938 c.-431T>C upstream_gene_variant 0.35 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.37 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGTG upstream_gene_variant 0.22 rifampicin
rpoA 3878991 c.-484C>A upstream_gene_variant 0.21 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3879015 c.-508G>A upstream_gene_variant 0.17 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.25 rifampicin
rpoA 3879033 c.-526C>T upstream_gene_variant 0.3 rifampicin
rpoA 3879034 c.-527G>C upstream_gene_variant 0.3 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 0.3 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.31 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.39 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.44 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.42 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.41 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.39 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.42 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.44 rifampicin
rpoA 3879190 c.-683C>T upstream_gene_variant 0.34 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.26 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.26 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.26 rifampicin
rpoA 3879238 c.-731C>G upstream_gene_variant 0.21 rifampicin
ddn 3986615 c.-229C>T upstream_gene_variant 0.29 pretomanid
delamanid
clpC1 4038278 c.2427T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038289 p.Asn806Asp missense_variant 0.31 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.29 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.28 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.29 pyrazinamide
clpC1 4038323 c.2382C>G synonymous_variant 0.3 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 0.37 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.41 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.42 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.42 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.36 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038389 c.2316G>A synonymous_variant 0.23 pyrazinamide
clpC1 4038486 p.Gly740Thr missense_variant 0.22 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.3 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.35 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.35 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4038596 c.2109A>G synonymous_variant 0.35 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.39 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.37 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.37 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.36 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.35 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.4 pyrazinamide
clpC1 4038674 c.2031C>G synonymous_variant 0.43 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2013C>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.26 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4038701 c.2004G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.24 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.32 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.36 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.51 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 0.53 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.53 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.43 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.38 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.36 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.32 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.43 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.42 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 0.42 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4039021 c.1684C>T synonymous_variant 0.49 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.43 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.4 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.39 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.31 pyrazinamide
clpC1 4039140 p.Glu522Val missense_variant 0.31 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.32 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.47 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.44 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 0.42 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.43 pyrazinamide
clpC1 4039268 c.1437C>T synonymous_variant 0.44 pyrazinamide
clpC1 4039274 c.1431G>T synonymous_variant 0.41 pyrazinamide
clpC1 4039277 c.1428C>T synonymous_variant 0.46 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 0.45 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.45 pyrazinamide
clpC1 4039319 p.Ala462Thr missense_variant 0.47 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 0.47 pyrazinamide
clpC1 4039328 c.1377A>T synonymous_variant 0.51 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.53 pyrazinamide
clpC1 4039355 c.1350G>T synonymous_variant 0.52 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.51 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.45 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.47 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.41 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.42 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.47 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039589 c.1116G>T synonymous_variant 0.33 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.27 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039715 c.990G>A synonymous_variant 0.39 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.38 pyrazinamide
clpC1 4039727 c.978C>T synonymous_variant 0.35 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.27 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.27 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.32 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039796 c.909C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039817 c.888A>T synonymous_variant 0.29 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.29 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.38 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.33 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039997 c.708C>T synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.36 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.3 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.39 pyrazinamide
clpC1 4040138 c.567G>C synonymous_variant 0.37 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>T synonymous_variant 0.23 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.2 pyrazinamide
clpC1 4040180 c.525C>G synonymous_variant 0.25 pyrazinamide
clpC1 4040243 c.462C>G synonymous_variant 0.25 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.28 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.28 pyrazinamide
clpC1 4040288 c.417C>T synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040321 c.384C>T synonymous_variant 0.47 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.42 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.32 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.31 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.37 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.29 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.33 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.26 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.26 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.28 pyrazinamide
clpC1 4040456 c.249C>T synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.27 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.36 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.41 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.28 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040549 c.154_156delTTGinsCTT synonymous_variant 0.33 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.33 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.29 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>T synonymous_variant 0.18 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.17 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.18 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.25 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.22 pyrazinamide
clpC1 4040657 c.48T>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4040669 c.36C>G synonymous_variant 0.21 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.28 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
panD 4044141 c.141C>G synonymous_variant 0.24 pyrazinamide
panD 4044150 c.132A>G synonymous_variant 0.24 pyrazinamide
panD 4044159 c.123C>T synonymous_variant 0.24 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 0.24 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 0.22 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
panD 4044188 c.94T>C synonymous_variant 0.26 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.23 pyrazinamide
panD 4044201 c.81C>G synonymous_variant 0.24 pyrazinamide
panD 4044225 c.57C>T synonymous_variant 0.22 pyrazinamide
panD 4044228 c.54C>T synonymous_variant 0.21 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 0.21 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.21 pyrazinamide
panD 4044240 c.42G>T synonymous_variant 0.21 pyrazinamide
panD 4044261 c.21G>A synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
panD 4044273 c.9G>C synonymous_variant 0.19 pyrazinamide
glpK 4138418 c.1338T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138424 c.1332T>C synonymous_variant 0.19 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138429 c.1327T>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138451 c.1305T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138472 c.1284G>C synonymous_variant 0.18 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138478 c.1278T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138502 c.1254T>G synonymous_variant 0.15 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139231 c.525A>C synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139242 c.514T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139243 c.513A>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139255 c.501G>A synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139258 c.498C>A synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139261 c.495C>G synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139270 c.486C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139273 c.483A>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139276 c.480T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139282 c.474T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139285 c.471A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139306 c.450C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139312 c.444T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139321 c.435T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139324 c.432A>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139327 c.429G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139339 c.417G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 0.21 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.25 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.25 ethambutol
embC 4239156 c.-707_-706delACinsTT upstream_gene_variant 0.27 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 0.29 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 0.29 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.29 ethambutol
embC 4239179 c.-684G>A upstream_gene_variant 0.3 ethambutol
embC 4239189 c.-674C>T upstream_gene_variant 0.28 ethambutol
embC 4239209 c.-654G>C upstream_gene_variant 0.28 ethambutol
embC 4239215 c.-648T>G upstream_gene_variant 0.23 ethambutol
embC 4239336 c.-527T>C upstream_gene_variant 0.2 ethambutol
embC 4239341 c.-522G>C upstream_gene_variant 0.25 ethambutol
embC 4239378 c.-485T>C upstream_gene_variant 0.28 ethambutol
embC 4239401 c.-462A>C upstream_gene_variant 0.25 ethambutol
embC 4239407 c.-456C>G upstream_gene_variant 0.21 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.19 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embC 4240741 c.879C>T synonymous_variant 0.29 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.42 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.39 ethambutol
embC 4240811 p.Phe317Leu missense_variant 0.33 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.32 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.28 ethambutol
embC 4240837 c.975C>G synonymous_variant 0.33 ethambutol
embC 4240859 p.Leu333Ile missense_variant 0.31 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.28 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.3 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.26 ethambutol
embC 4240885 c.1023T>C synonymous_variant 0.24 ethambutol
embC 4240918 c.1056G>C synonymous_variant 0.23 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.24 ethambutol
embC 4240927 c.1065C>T synonymous_variant 0.24 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.26 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.32 ethambutol
embC 4241101 c.1239G>C synonymous_variant 0.34 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.32 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embC 4241551 c.1689A>C synonymous_variant 0.18 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.23 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.28 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.3 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.26 ethambutol
embC 4241617 c.1755G>A synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embC 4241623 c.1761C>A synonymous_variant 0.2 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.2 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.19 ethambutol
embC 4242375 p.Arg838Gln missense_variant 0.38 ethambutol Uncertain significance
embA 4242391 c.-842G>T upstream_gene_variant 0.41 ethambutol
embA 4242400 c.-833C>G upstream_gene_variant 0.43 ethambutol
embC 4242402 p.Arg847His missense_variant 0.44 ethambutol Uncertain significance
embA 4242406 c.-827A>T upstream_gene_variant 0.46 ethambutol
embA 4242427 c.-806A>G upstream_gene_variant 0.38 ethambutol
embC 4242428 p.Ala856Pro missense_variant 0.38 ethambutol
embC 4242434 p.Val858Ile missense_variant 0.36 ethambutol
embA 4242448 c.-785C>G upstream_gene_variant 0.26 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4242805 c.-428G>A upstream_gene_variant 0.23 ethambutol
embA 4242826 c.-407G>C upstream_gene_variant 0.25 ethambutol
embA 4242827 c.-406C>T upstream_gene_variant 0.24 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 0.27 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.27 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.26 ethambutol
embC 4242847 c.2985C>G synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embA 4242853 c.-380C>T upstream_gene_variant 0.27 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.32 ethambutol
embA 4242895 c.-338C>T upstream_gene_variant 0.32 ethambutol
embC 4242904 c.3042C>T synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embA 4242910 c.-323C>T upstream_gene_variant 0.22 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.2 ethambutol
embA 4242925 c.-308C>T upstream_gene_variant 0.18 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244885 c.1653A>G synonymous_variant 0.36 ethambutol
embA 4244886 c.1654C>T synonymous_variant 0.36 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.39 ethambutol
embA 4244904 p.Val558Leu missense_variant 0.36 ethambutol Uncertain significance
embA 4244909 c.1677C>G synonymous_variant 0.32 ethambutol
embA 4244916 c.1684C>T synonymous_variant 0.3 ethambutol
embA 4244921 c.1689C>G synonymous_variant 0.29 ethambutol
embA 4245093 p.Ile621Val missense_variant 0.17 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 0.27 ethambutol
embA 4245136 p.Tyr635Phe missense_variant 0.37 ethambutol
embA 4245149 c.1917C>A synonymous_variant 0.42 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.41 ethambutol
embA 4245174 p.Ser648Thr missense_variant 0.43 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.42 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.4 ethambutol
embA 4245198 p.Leu656Ala missense_variant 0.24 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.21 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.2 ethambutol
embB 4245713 c.-801G>C upstream_gene_variant 0.21 ethambutol
embB 4245725 c.-789A>C upstream_gene_variant 0.19 ethambutol
embB 4245726 c.-788_-786delTTGinsCTC upstream_gene_variant 0.19 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.19 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.21 ethambutol
embB 4247371 c.858C>G synonymous_variant 0.17 ethambutol
embB 4247380 c.867C>G synonymous_variant 0.18 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.18 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.19 ethambutol
embB 4247395 c.882C>A synonymous_variant 0.24 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.24 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embB 4247446 c.933C>T synonymous_variant 0.26 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.28 ethambutol
embB 4247494 c.981G>A synonymous_variant 0.27 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.28 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.28 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.34 ethambutol
embB 4247519 c.1006C>T synonymous_variant 0.35 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.27 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.23 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.2 ethambutol
embB 4247576 c.1063C>T synonymous_variant 0.2 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.2 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.18 ethambutol Not assoc w R - Interim
embB 4247972 p.Thr487Phe missense_variant 0.32 ethambutol
embB 4247977 c.1464C>G synonymous_variant 0.32 ethambutol
embB 4247983 c.1470G>C synonymous_variant 0.39 ethambutol
embB 4247992 c.1479G>A synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 0.49 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.57 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.59 ethambutol Uncertain significance
embB 4248044 p.Lys511Asp missense_variant 0.57 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.52 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.4 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.36 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.35 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.28 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.19 ethambutol
embB 4248172 c.1659G>C synonymous_variant 0.23 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.22 ethambutol
embB 4248199 c.1686A>C synonymous_variant 0.18 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.18 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.19 ethambutol Uncertain significance
embB 4248211 c.1698G>C synonymous_variant 0.19 ethambutol
embB 4248217 c.1704C>G synonymous_variant 0.18 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embB 4248226 c.1713G>C synonymous_variant 0.19 ethambutol
embB 4248232 c.1719G>A synonymous_variant 0.22 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 0.22 ethambutol
embB 4248241 c.1728C>T synonymous_variant 0.23 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.23 ethambutol
embB 4248280 c.1767C>G synonymous_variant 0.26 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.32 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.32 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.33 ethambutol
embB 4248328 c.1815G>A synonymous_variant 0.31 ethambutol
embB 4248337 c.1824G>C synonymous_variant 0.29 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.25 ethambutol
embB 4249343 p.Val944Ile missense_variant 0.32 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.3 ethambutol
embB 4249354 c.2841G>A synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embB 4249369 c.2856T>C synonymous_variant 0.39 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.38 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.38 ethambutol
embB 4249382 p.Pro957Ala missense_variant 0.38 ethambutol
embB 4249387 p.Glu958Asp missense_variant 0.38 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.45 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.44 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 0.4 ethambutol
embB 4249433 c.2920C>T synonymous_variant 0.43 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.39 ethambutol
embB 4249447 c.2934G>C synonymous_variant 0.4 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.39 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.28 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.28 ethambutol
embB 4249492 c.2979C>A synonymous_variant 0.3 ethambutol
aftB 4267622 c.1213_1215delTCGinsAGC synonymous_variant 0.18 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.17 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.19 ethambutol
aftB 4267647 p.Asp397Cys missense_variant 0.82 ethambutol
aftB 4267655 c.1182C>G synonymous_variant 0.19 ethambutol
aftB 4268096 c.741C>T synonymous_variant 0.23 ethambutol
aftB 4268099 c.738G>T synonymous_variant 0.24 ethambutol
aftB 4268105 c.732T>C synonymous_variant 0.23 ethambutol
aftB 4268120 c.717C>G synonymous_variant 0.24 ethambutol
aftB 4268123 p.Ser238Gly missense_variant 0.25 ethambutol
aftB 4268126 c.711G>C synonymous_variant 0.25 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.25 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.27 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.26 ethambutol
ubiA 4269131 p.Leu235Met missense_variant 0.19 ethambutol Uncertain significance
aftB 4269138 c.-302C>T upstream_gene_variant 0.24 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
ubiA 4269152 p.Ala228Ser missense_variant 0.24 ethambutol Uncertain significance
aftB 4269153 c.-317C>G upstream_gene_variant 0.24 ethambutol
aftB 4269156 c.-320C>G upstream_gene_variant 0.24 ethambutol
aftB 4269164 c.-328T>C upstream_gene_variant 0.27 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 0.3 ethambutol Not assoc w R - Interim
aftB 4269183 c.-347T>C upstream_gene_variant 0.35 ethambutol
aftB 4269210 c.-374G>A upstream_gene_variant 0.39 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.37 ethambutol Not assoc w R - Interim
aftB 4269225 c.-389C>A upstream_gene_variant 0.36 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 0.33 ethambutol
aftB 4269242 c.-406C>T upstream_gene_variant 0.31 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.31 ethambutol
aftB 4269248 c.-412C>T upstream_gene_variant 0.32 ethambutol
aftB 4269252 c.-416C>G upstream_gene_variant 0.31 ethambutol
aftB 4269267 c.-431C>G upstream_gene_variant 0.24 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R