TB-Profiler result

Run: ERR294266
Summary

Run ID: ERR294266

Sample name:

Date: 2024-10-04T01:44:23.410443

Number of reads: 658523

Percentage reads mapped: 18.38

Median coverage: 5.0

Strain: lineage4.2;lineage4.8.1;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.12
lineage4.2 Euro-American None 0.15
lineage4 Euro-American None 0.81
lineage4.8.1 Euro-American (mainly T) RD219 0.07
lineage4.9 Euro-American (H37Rv-like) None 0.8
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
p.Ile317Leu Mutation from literature
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
katG 2155108 p.Ile335Thr missense_variant 0.95 isoniazid Mutation from literature
katG 2155163 p.Ile317Leu missense_variant 0.8 isoniazid Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.97 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 0.94 isoniazid
dnaA 24 c.24C>T synonymous_variant 0.94 isoniazid
dnaA 30 c.30C>G synonymous_variant 0.94 isoniazid
dnaA 42 c.42C>T synonymous_variant 0.93 isoniazid
dnaA 54 c.54C>T synonymous_variant 0.9 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.67 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.67 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.67 isoniazid
dnaA 759 c.759C>T synonymous_variant 0.67 isoniazid
dnaA 762 c.762C>G synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 768 c.768C>T synonymous_variant 0.67 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.67 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.76 isoniazid
dnaA 789 c.789C>T synonymous_variant 0.88 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 804 c.804G>C synonymous_variant 0.88 isoniazid
dnaA 805 c.805T>C synonymous_variant 0.88 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.94 isoniazid
dnaA 831 c.831A>G synonymous_variant 0.93 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.94 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.94 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.92 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.92 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.92 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.94 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.93 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.91 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.9 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.86 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.86 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.88 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.88 isoniazid
dnaA 960 c.960C>G synonymous_variant 0.88 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.89 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.89 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.93 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.93 isoniazid
dnaA 993 c.993A>G synonymous_variant 0.93 isoniazid
dnaA 996 c.996A>T synonymous_variant 0.96 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 0.98 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.98 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.97 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.97 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.96 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.96 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1134 c.1134G>C synonymous_variant 0.96 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.88 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 0.87 isoniazid
dnaA 1239 c.1239G>A synonymous_variant 0.81 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.86 isoniazid
dnaA 1260 c.1260C>T synonymous_variant 0.95 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.95 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.96 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.97 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.97 isoniazid
dnaA 1291 c.1291_1293delCTTinsTTA synonymous_variant 0.97 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.94 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 1332 c.1332A>C synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.9 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 0.89 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.88 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.89 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.91 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.96 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.97 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
gyrB 6091 c.852G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.73 levofloxacin
moxifloxacin
gyrB 6127 c.888G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 6205 c.966C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 0.95 levofloxacin
moxifloxacin
gyrB 6266 p.Pro343Ala missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.97 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6440 p.Thr401Ser missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6445 p.Asp402Glu missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6452 p.Val405Thr missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 6466 c.-836G>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6481 c.1242G>A synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6484 c.-818A>G upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6511 c.-791A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6542 p.Ile435Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6559 c.1320C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6625 c.-677G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6664 c.1425C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6674 c.-628_-626delCTTinsTTG upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.79 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.85 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7186 c.-116C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7595 c.294C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7727 c.426G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7781 c.480G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7814 c.513C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8165 c.864C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8186 c.885G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8195 c.894C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8240 c.939C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8345 c.1044C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8354 c.1053G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9017 c.1716C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9083 c.1782G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.83 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>A synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9182 c.1881T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 0.77 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9206 c.1905C>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9209 c.1908G>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9266 c.1965C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9317 c.2016G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCGA synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9392 c.2091C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13882 c.-326_-324delATCinsGTG upstream_gene_variant 0.8 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.85 isoniazid
Rv0010c 13893 c.-335T>A upstream_gene_variant 0.8 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.85 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.85 isoniazid
fgd1 490803 c.21T>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490818 c.36C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490851 c.69A>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 490854 c.72C>T synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 490857 c.75C>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fgd1 490869 c.87C>A synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fgd1 490875 c.93C>T synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491064 c.282A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491112 c.330G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491168 p.Phe129Tyr missense_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491172 c.390C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491623 p.Ala281Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491673 c.891A>C synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fgd1 491679 c.897A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491688 c.906A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491703 c.921C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491704 c.922C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491709 c.927A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575495 c.148C>T synonymous_variant 0.91 isoniazid
ethionamide
mshA 575500 c.153G>A synonymous_variant 0.92 isoniazid
ethionamide
mshA 575521 c.174A>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575524 c.177G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575527 c.180G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575530 c.183C>T synonymous_variant 0.94 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575548 c.201C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575557 c.210C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575560 c.213C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 1.0 isoniazid
ethionamide
mshA 575572 c.225T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575576 c.229C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575587 c.240C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575596 c.249C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575629 c.282A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575634 p.Ala96Val missense_variant 1.0 isoniazid
ethionamide
mshA 575641 c.294A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575650 c.303G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575651 p.Arg102Glu missense_variant 1.0 isoniazid
ethionamide
mshA 575656 c.309G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575658 p.Ala104Glu missense_variant 1.0 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575680 c.333C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.96 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.96 isoniazid
ethionamide
mshA 575860 c.513G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575887 c.540G>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575896 c.549G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575908 c.561A>G synonymous_variant 0.92 isoniazid
ethionamide
mshA 575916 p.Asp190Ala missense_variant 0.92 isoniazid
ethionamide
mshA 575925 p.Gly193Ala missense_variant 0.92 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.89 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.89 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 0.92 isoniazid
ethionamide
mshA 575984 c.637T>C synonymous_variant 0.92 isoniazid
ethionamide
mshA 576001 c.654C>T synonymous_variant 0.92 isoniazid
ethionamide
mshA 576010 c.663C>G synonymous_variant 0.95 isoniazid
ethionamide
mshA 576011 c.664_666delAGGinsCGA synonymous_variant 0.95 isoniazid
ethionamide
mshA 576017 p.Val224Leu missense_variant 0.95 isoniazid
ethionamide
mshA 576026 p.Leu227Ile missense_variant 0.9 isoniazid
ethionamide
mshA 576032 p.Gly229Asn missense_variant 0.9 isoniazid
ethionamide
mshA 576045 p.Ala233Gly missense_variant 0.95 isoniazid
ethionamide
mshA 576070 c.723T>C synonymous_variant 0.82 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619535 c.-356_-354delCAAinsGAC upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619543 c.-348C>G upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257_-256delTCinsGT upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619669 c.-222G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619678 c.-213G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619681 c.-210G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619899 c.9G>C synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 619911 c.21C>T synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 619912 p.Val8Ile missense_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 619923 c.33C>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 619929 c.39C>T synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 619953 c.63C>G synonymous_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 619957 p.Val23Leu missense_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 619962 c.72G>C synonymous_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 620197 p.Gln103Met missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620238 c.348G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620269 p.Val127Ile missense_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620291 p.Tyr134Phe missense_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>C synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620298 c.408G>T synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620301 c.411G>T synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.98 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>C synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.98 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>C synonymous_variant 0.98 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.98 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.95 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.95 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 0.92 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>C synonymous_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620583 c.693G>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620634 c.744C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620664 c.774C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620676 c.786C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620763 c.873G>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620773 p.Ile295Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620800 p.Val304Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620809 c.919C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620844 c.954C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
Rv0565c 656262 c.1209C>G synonymous_variant 0.8 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.83 ethionamide
Rv0565c 656271 c.1200C>T synonymous_variant 0.83 ethionamide
Rv0565c 656277 c.1194C>A synonymous_variant 0.85 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.85 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.85 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.85 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.94 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.94 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.94 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 0.95 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 0.97 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.95 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.95 ethionamide
Rv0565c 657240 p.Glu77Lys missense_variant 0.95 ethionamide
Rv0565c 657252 c.219G>C synonymous_variant 0.97 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.97 ethionamide
Rv0565c 657267 c.204G>T synonymous_variant 0.97 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 1.0 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 1.0 ethionamide
Rv0565c 657309 c.162C>G synonymous_variant 1.0 ethionamide
Rv0565c 657640 c.-170A>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731729 c.-201C>T upstream_gene_variant 0.92 isoniazid
hadA 731742 c.-188A>G upstream_gene_variant 0.93 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.94 isoniazid
hadA 731765 c.-165C>T upstream_gene_variant 0.96 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.96 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.96 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.97 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.97 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.94 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.88 isoniazid
hadA 732320 p.Glu131Asn missense_variant 0.88 isoniazid
hadA 732325 c.396T>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
hadA 732328 p.Asp133Glu missense_variant 0.88 isoniazid Uncertain significance
hadA 732329 p.Leu134Thr missense_variant 0.88 isoniazid
hadA 732334 c.405G>C synonymous_variant 0.89 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.93 isoniazid
hadA 732367 c.438C>G synonymous_variant 0.95 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.96 isoniazid
hadA 732385 c.456A>G synonymous_variant 0.97 isoniazid
hadA 732389 p.Ser154Ala missense_variant 0.97 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.97 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.97 isoniazid
nusG 734053 c.-201A>T upstream_gene_variant 1.0 rifampicin
nusG 734078 c.-176C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734093 c.-161A>G upstream_gene_variant 0.95 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.95 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.95 rifampicin
nusG 734118 c.-136_-134delCTTinsTTC upstream_gene_variant 0.95 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.97 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 0.96 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.96 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.96 rifampicin
nusG 734173 c.-81_-80delCCinsGA upstream_gene_variant 0.89 rifampicin
nusG 734175 c.-79_-78delGGinsCT upstream_gene_variant 0.89 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 0.89 rifampicin
nusG 734184 c.-70_-68delTTGinsCTT upstream_gene_variant 0.89 rifampicin
nusG 734201 c.-53G>C upstream_gene_variant 0.96 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 0.96 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.96 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 0.95 rifampicin
nusG 734225 c.-29C>T upstream_gene_variant 0.95 rifampicin
nusG 734232 c.-22G>A upstream_gene_variant 0.94 rifampicin
nusG 734233 c.-21T>A upstream_gene_variant 0.94 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 0.94 rifampicin
nusG 734283 c.30G>C synonymous_variant 0.9 rifampicin
nusG 734415 c.162C>T synonymous_variant 0.93 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734448 c.195C>T synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734505 c.252G>A synonymous_variant 1.0 rifampicin
nusG 734520 c.267C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734844 c.591G>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734875 p.Val208Ile missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734905 c.652C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734943 c.690G>C synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Thr missense_variant 1.0 rifampicin
mmaA3 737310 c.840A>G synonymous_variant 0.85 isoniazid
mmaA3 737316 c.834G>A synonymous_variant 0.76 isoniazid
mmaA3 737320 p.Lys277Arg missense_variant 0.76 isoniazid
mmaA3 737324 p.Ala276Ser missense_variant 0.76 isoniazid
mmaA3 737338 p.Tyr271Phe missense_variant 0.73 isoniazid
mmaA3 737340 c.810A>G synonymous_variant 0.7 isoniazid
mmaA3 737358 c.792A>C synonymous_variant 0.91 isoniazid
mmaA3 737365 p.Ala262Glu missense_variant 0.86 isoniazid
mmaA3 737376 c.774G>A synonymous_variant 0.64 isoniazid
mmaA3 737381 p.Ile257Val missense_variant 0.58 isoniazid
mmaA3 737885 p.Val89Ile missense_variant 0.9 isoniazid
mmaA3 737889 p.Arg87His missense_variant 0.89 isoniazid
mmaA3 737898 c.252C>G synonymous_variant 0.95 isoniazid
mmaA3 737916 c.234C>T synonymous_variant 0.93 isoniazid
mmaA3 737919 p.Val77Ile missense_variant 0.92 isoniazid
mmaA3 737922 c.228C>T synonymous_variant 0.93 isoniazid
mmaA3 737931 c.219A>C synonymous_variant 0.93 isoniazid
mmaA3 737937 c.213A>G synonymous_variant 0.93 isoniazid
mmaA3 737943 c.207A>G synonymous_variant 0.93 isoniazid
mmaA3 737946 c.204A>G synonymous_variant 0.93 isoniazid
mmaA3 738303 c.-155_-154delCGinsAA upstream_gene_variant 0.35 isoniazid
mmaA3 738309 c.-160G>C upstream_gene_variant 0.36 isoniazid
mmaA3 738315 c.-166G>A upstream_gene_variant 0.93 isoniazid
mmaA3 738329 c.-180A>G upstream_gene_variant 0.43 isoniazid
mmaA3 738336 c.-188_-187delTCinsAA upstream_gene_variant 0.43 isoniazid
mmaA3 738346 c.-198_-197delCTinsGC upstream_gene_variant 0.93 isoniazid
mmaA3 738348 c.-199G>C upstream_gene_variant 0.94 isoniazid
rpoB 759629 c.-178T>C upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.93 rifampicin Uncertain significance
rpoB 760088 c.282C>G synonymous_variant 0.95 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.98 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.97 rifampicin
rpoB 760172 c.366G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760356 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760403 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.92 rifampicin
rpoB 760754 c.948G>C synonymous_variant 1.0 rifampicin
rpoB 760755 p.His317Asn missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760796 c.990A>G synonymous_variant 0.96 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.95 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 0.95 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.9 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.91 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.9 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 0.91 rifampicin
rpoB 760877 c.1071G>T synonymous_variant 0.94 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.97 rifampicin
rpoB 760919 c.1113C>T synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>A synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 1.0 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>T synonymous_variant 0.97 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.91 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.93 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.97 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.97 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 1.0 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.96 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>G synonymous_variant 0.95 rifampicin
rpoB 761282 c.1476C>T synonymous_variant 0.96 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.97 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761373 p.Val523Gln missense_variant 0.95 rifampicin
rpoB 761387 c.1581C>G synonymous_variant 0.94 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.82 rifampicin
rpoB 761414 c.1608A>T synonymous_variant 0.8 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.73 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.87 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.9 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.9 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.96 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>A synonymous_variant 0.94 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.92 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761816 c.2010C>G synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761955 p.Ile717Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 0.93 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.93 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762347 c.2541T>C synonymous_variant 0.87 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.91 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 0.9 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.9 rifampicin
rpoC 762374 c.-996G>T upstream_gene_variant 0.95 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762494 c.-876G>A upstream_gene_variant 1.0 rifampicin
rpoC 762800 c.-570C>G upstream_gene_variant 1.0 rifampicin
rpoC 762812 c.-558C>A upstream_gene_variant 1.0 rifampicin
rpoB 762814 p.Met1003Arg missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762824 c.-546C>T upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762957 c.3151C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.98 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.98 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.96 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763199 c.-171G>T upstream_gene_variant 0.95 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.91 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.91 rifampicin
rpoC 763211 c.-159C>T upstream_gene_variant 0.91 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.9 rifampicin
rpoC 763238 c.-132T>G upstream_gene_variant 0.9 rifampicin
rpoC 763247 c.-123G>A upstream_gene_variant 0.87 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.88 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.82 rifampicin
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763405 c.36C>T synonymous_variant 0.96 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.97 rifampicin
rpoC 763420 c.51G>T synonymous_variant 0.97 rifampicin
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.97 rifampicin
rpoC 763435 c.66A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.97 rifampicin
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763711 c.342G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>A synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763778 p.Thr137Val missense_variant 1.0 rifampicin
rpoC 763781 p.Ser138Gly missense_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763852 c.483C>T synonymous_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>C synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763933 c.564C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764015 c.646C>T synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.94 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764212 c.843C>T synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764263 c.894G>C synonymous_variant 0.96 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.97 rifampicin
rpoC 764272 c.903G>T synonymous_variant 0.97 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.97 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.98 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.98 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.98 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>T synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>A synonymous_variant 0.97 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.96 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.97 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.96 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765065 c.1696C>T synonymous_variant 0.95 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.93 rifampicin
rpoC 765079 c.1710T>A synonymous_variant 0.93 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.93 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765350 p.Ala661Ser missense_variant 1.0 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.96 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.96 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.96 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.92 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765571 c.2202C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765578 c.2209C>T synonymous_variant 0.93 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 0.94 rifampicin
rpoC 765592 c.2223C>T synonymous_variant 0.94 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.96 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765640 c.2271A>G synonymous_variant 0.96 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 1.0 rifampicin
rpoC 765734 c.2365_2367delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.95 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.97 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.96 rifampicin
rpoC 766030 c.2661C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 0.97 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.87 rifampicin
rpoC 766080 c.2712delT frameshift_variant 0.88 rifampicin
rpoC 766084 c.2715_2716insG frameshift_variant 0.81 rifampicin
rpoC 766090 c.2721C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766096 c.2727G>C synonymous_variant 0.87 rifampicin
rpoC 766097 c.2728C>T synonymous_variant 0.87 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.89 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.83 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.81 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 0.81 rifampicin Uncertain significance
rpoC 766171 c.2802C>T synonymous_variant 0.82 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.82 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.72 rifampicin
rpoC 766193 p.Gln942Glu missense_variant 0.62 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.79 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.81 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 0.87 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.83 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.89 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.9 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.93 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.94 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.96 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.97 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.97 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766469 c.3100C>T synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.97 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.97 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.96 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.96 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.98 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.98 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.91 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.94 rifampicin
rpoC 767065 c.3696G>C synonymous_variant 0.91 rifampicin
rpoC 767066 c.3697C>T synonymous_variant 0.89 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.88 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 0.9 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.93 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.94 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>A synonymous_variant 1.0 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775864 p.Ala873Ser missense_variant 1.0 bedaquiline
clofazimine
mmpL5 775865 c.2616T>G synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 775874 c.2607C>A synonymous_variant 0.71 bedaquiline
clofazimine
mmpL5 775880 p.Asn867Lys missense_variant 0.35 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.44 bedaquiline
clofazimine
mmpL5 775886 c.2595A>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.85 bedaquiline
clofazimine
mmpL5 775912 c.2569C>A synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 775913 p.Ala856Ser missense_variant 0.85 bedaquiline
clofazimine
mmpL5 775916 c.2565T>A synonymous_variant 0.55 bedaquiline
clofazimine
mmpL5 775927 c.2554C>T synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 775937 p.Ala848Ser missense_variant 0.57 bedaquiline
clofazimine
mmpL5 775949 c.2532G>C synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.9 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.95 bedaquiline
clofazimine
mmpL5 775993 p.Glu830Lys missense_variant 0.77 bedaquiline
clofazimine
mmpL5 775997 c.2484T>G synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 776003 c.2478C>T synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 776008 p.His825Tyr missense_variant 0.77 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 776015 p.Ile822Leu missense_variant 0.77 bedaquiline
clofazimine
mmpL5 776024 c.2457G>C synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 776027 c.2454G>C synonymous_variant 0.96 bedaquiline
clofazimine
mmpL5 776030 c.2451G>A synonymous_variant 0.92 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 776056 p.Val809Leu missense_variant 0.83 bedaquiline
clofazimine
mmpL5 776060 c.2421C>G synonymous_variant 0.88 bedaquiline
clofazimine
mmpL5 776072 c.2409C>G synonymous_variant 0.87 bedaquiline
clofazimine
mmpL5 776076 p.Ala802Phe missense_variant 0.83 bedaquiline
clofazimine
mmpL5 776084 c.2397C>A synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 776093 c.2388C>A synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776102 p.Ile793Val missense_variant 0.71 bedaquiline
clofazimine
mmpL5 776120 c.2361C>T synonymous_variant 0.75 bedaquiline
clofazimine
mmpL5 777158 c.1323C>G synonymous_variant 0.73 bedaquiline
clofazimine
mmpL5 777161 p.Gln440His missense_variant 0.73 bedaquiline
clofazimine
mmpL5 777164 c.1317C>G synonymous_variant 0.8 bedaquiline
clofazimine
mmpL5 777179 c.1302G>C synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777185 c.1296G>C synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777191 c.1290C>A synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777203 c.1278G>C synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777209 c.1272C>T synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777212 c.1269C>G synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777626 c.855C>T synonymous_variant 0.67 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 777629 c.852C>A synonymous_variant 0.67 bedaquiline
clofazimine
mmpL5 777640 c.841C>T synonymous_variant 0.73 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 777647 c.834C>G synonymous_variant 0.73 bedaquiline
clofazimine
mmpL5 777678 p.Val268Thr missense_variant 0.73 bedaquiline
clofazimine
mmpL5 777680 c.801G>C synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 777683 c.798C>A synonymous_variant 0.73 bedaquiline
clofazimine
mmpL5 777689 c.792C>T synonymous_variant 0.73 bedaquiline
clofazimine
mmpL5 777701 c.780C>A synonymous_variant 0.8 bedaquiline
clofazimine
rpsL 781571 c.12C>T synonymous_variant 0.96 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.96 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.96 streptomycin
rpsL 781601 c.42C>T synonymous_variant 0.96 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.96 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.98 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.98 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.95 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.95 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.94 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.94 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.94 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.93 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.92 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.92 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.9 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.9 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.92 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 0.97 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.97 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.97 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.93 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.97 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.93 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.93 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.92 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.91 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.91 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.86 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.93 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.95 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.98 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.98 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.98 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.98 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.96 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.96 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.95 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.98 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94_-92delATCinsCTT upstream_gene_variant 0.98 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.98 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800916 c.108A>C synonymous_variant 0.8 linezolid
rplC 800919 c.111C>G synonymous_variant 0.8 linezolid
rplC 800922 c.114C>G synonymous_variant 0.86 linezolid
rplC 800931 c.123G>C synonymous_variant 0.9 linezolid
rplC 800934 c.126C>G synonymous_variant 0.9 linezolid
rplC 800939 p.Arg44Leu missense_variant 0.91 linezolid Uncertain significance
rplC 800949 c.141T>C synonymous_variant 0.92 linezolid
rplC 800962 c.154C>T synonymous_variant 0.96 linezolid
rplC 800976 c.168G>A synonymous_variant 0.97 linezolid
rplC 801003 c.195G>C synonymous_variant 0.95 linezolid
rplC 801004 p.Leu66Val missense_variant 0.95 linezolid
rplC 801009 c.201A>G synonymous_variant 0.95 linezolid Not assoc w R - Interim
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 0.92 linezolid
rplC 801174 c.366T>C synonymous_variant 0.92 linezolid
rplC 801183 c.375C>A synonymous_variant 0.93 linezolid
rplC 801195 c.387G>T synonymous_variant 0.93 linezolid
rplC 801198 c.390C>T synonymous_variant 0.93 linezolid
rplC 801207 c.399C>T synonymous_variant 0.94 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>T synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801285 c.477G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801300 c.492C>G synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 0.97 linezolid
rplC 801312 c.504G>T synonymous_variant 1.0 linezolid
rplC 801321 c.513C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801349 p.Leu181Val missense_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801363 c.555C>G synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801417 c.609T>C synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
Rv1129c 1253614 c.921C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253632 c.903T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
Rv1129c 1253635 c.900C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253638 c.897A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253641 p.Gln298Glu missense_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253653 c.882T>G synonymous_variant 0.89 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253665 p.Arg290Gly missense_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253683 c.852C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253686 c.849C>A synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253707 c.828A>C synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
Rv1129c 1253716 c.819G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253730 p.Ala269Ser missense_variant 0.92 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
Rv1129c 1253743 p.Gln264Arg missense_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253746 p.Asp263His missense_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253749 c.786T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
fbiC 1303233 c.303T>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1303242 c.312T>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1303251 c.321C>T synonymous_variant 0.83 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303272 c.342A>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303281 c.351A>G synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1303284 c.354T>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303285 p.Ser119Ala missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303288 p.Ser120Gly missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303292 p.Thr121Met missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303297 p.Met123Leu missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303302 c.372A>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303314 c.384C>T synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303321 p.Val131Ile missense_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303464 c.534A>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303468 p.Arg180Gly missense_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303480 p.Gln184Glu missense_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1303506 c.576C>T synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303521 c.591C>T synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303538 p.Arg203Leu missense_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>C synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303623 c.693C>T synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>G synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1303661 p.Val244Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303665 c.735G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303680 c.750G>A synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303695 c.765T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303722 c.792C>G synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303740 c.810C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303746 c.816T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303779 c.849G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303788 c.858T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303797 c.867A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303896 c.966G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303938 c.1008C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303953 p.Asp341Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303956 c.1026A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303971 c.1041T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303977 c.1047C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304172 c.1242G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304184 c.1254G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304545 p.Val539Thr missense_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304553 c.1623C>T synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>A synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>G synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1304805 c.1875G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304820 c.1890G>A synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>A synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304853 c.1923C>T synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304913 c.1983G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304915 p.Asp662Gly missense_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1304955 c.2025G>A synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1305393 c.2463T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1305396 c.2466C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1305400 p.His824Tyr missense_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1305405 c.2475A>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1305411 c.2481C>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1305417 c.2487C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
sigE 1364835 c.423C>G synonymous_variant 0.73 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.8 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.89 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.9 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.9 pyrazinamide
sigE 1364875 c.463C>A synonymous_variant 0.9 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.9 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.95 pyrazinamide
sigE 1364892 c.480C>G synonymous_variant 0.95 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.96 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 1.0 pyrazinamide
sigE 1364954 p.Arg181His missense_variant 1.0 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 1.0 pyrazinamide
sigE 1364962 p.Pro184Ala missense_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.89 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.88 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.9 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.91 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.87 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.86 pyrazinamide
sigE 1365078 c.666C>G synonymous_variant 0.86 pyrazinamide
sigE 1365081 c.669G>C synonymous_variant 0.84 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.84 pyrazinamide
sigE 1365087 c.675A>G synonymous_variant 0.84 pyrazinamide
sigE 1365096 c.684G>A synonymous_variant 0.76 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.75 pyrazinamide
sigE 1365111 c.699C>T synonymous_variant 0.71 pyrazinamide
sigE 1365117 c.705A>T synonymous_variant 0.73 pyrazinamide
sigE 1365118 c.706C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
embR 1416643 c.705G>C synonymous_variant 1.0 ethambutol
embR 1416649 c.699A>G synonymous_variant 1.0 ethambutol
embR 1416664 c.684T>C synonymous_variant 1.0 ethambutol
embR 1416667 c.681C>G synonymous_variant 1.0 ethambutol
embR 1416671 p.Gly226Ala missense_variant 1.0 ethambutol
embR 1416679 c.669T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embR 1416691 c.657C>T synonymous_variant 1.0 ethambutol
embR 1416696 p.Ser218Thr missense_variant 1.0 ethambutol
embR 1416697 c.651C>G synonymous_variant 1.0 ethambutol
embR 1416717 c.631C>T synonymous_variant 0.94 ethambutol
embR 1416721 p.Thr209Ala missense_variant 0.92 ethambutol
atpE 1461197 c.153A>G synonymous_variant 0.91 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.83 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.77 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.71 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.71 bedaquiline
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 0.83 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.84 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.84 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.74 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 0.71 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474108 n.451C>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474156 n.499G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629C>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474291 n.635_651delTTCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474311 n.654_655insAA non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.73 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
inhA 1673601 c.-601G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673615 c.-587_-586delAAinsTG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673657 c.-545_-544delCGinsAA upstream_gene_variant 0.91 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 0.91 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 0.91 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 0.91 isoniazid
ethionamide
inhA 1673697 c.-505G>A upstream_gene_variant 0.89 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 0.9 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674083 c.-119_-118delCCinsAG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674120 c.-82G>A upstream_gene_variant 0.96 isoniazid
ethionamide
inhA 1674129 c.-73C>T upstream_gene_variant 0.96 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 0.96 isoniazid
ethionamide
inhA 1674136 c.-66T>G upstream_gene_variant 0.96 isoniazid
ethionamide
inhA 1674147 c.-55C>T upstream_gene_variant 0.96 isoniazid
ethionamide
inhA 1674150 c.-52C>A upstream_gene_variant 0.96 isoniazid
ethionamide
inhA 1674156 c.-46C>T upstream_gene_variant 0.95 isoniazid
ethionamide
inhA 1674171 c.-31T>C upstream_gene_variant 0.86 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.85 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674504 c.303C>G synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674531 c.330C>T synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.95 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674549 c.348G>T synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674660 c.459G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674687 c.486G>A synonymous_variant 0.94 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674703 c.502T>C synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674718 c.517_519delAGGinsCGC synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674726 c.525G>C synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674732 c.531C>T synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674741 c.540C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674745 p.Tyr182Ala missense_variant 0.94 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674774 c.573A>C synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674792 c.591G>C synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674837 c.636C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674846 p.Ile215Met missense_variant 0.95 isoniazid
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.97 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.97 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.95 isoniazid
ethionamide
inhA 1674912 c.711G>C synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674930 c.729C>T synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833271 c.-271G>A upstream_gene_variant 0.75 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 0.75 pyrazinamide
rpsA 1833280 c.-262G>A upstream_gene_variant 0.79 pyrazinamide
rpsA 1833283 c.-259C>A upstream_gene_variant 0.73 pyrazinamide
rpsA 1833288 c.-254T>C upstream_gene_variant 0.85 pyrazinamide
rpsA 1833305 c.-237G>A upstream_gene_variant 0.85 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.75 pyrazinamide
rpsA 1833315 c.-227C>A upstream_gene_variant 0.83 pyrazinamide
rpsA 1833317 c.-225_-223delCTCinsTTG upstream_gene_variant 0.83 pyrazinamide
rpsA 1833325 c.-217C>G upstream_gene_variant 0.83 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.95 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 0.97 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.97 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1833782 p.Ser81Thr missense_variant 0.96 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.94 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.93 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833883 c.342C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 0.96 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.97 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTTG synonymous_variant 0.97 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.93 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834351 c.810G>A synonymous_variant 0.95 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834405 c.864C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 0.89 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.95 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834726 c.1185C>T synonymous_variant 0.88 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.96 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.96 linezolid
tsnR 1853394 c.-212_-210delCTCinsGCG upstream_gene_variant 0.91 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.93 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.92 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.88 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.88 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.89 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.89 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.89 linezolid
tsnR 1853468 c.-138C>T upstream_gene_variant 0.91 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.93 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.93 linezolid
tsnR 1853495 c.-111G>A upstream_gene_variant 0.93 linezolid
tsnR 1853516 c.-90C>T upstream_gene_variant 0.87 linezolid
tsnR 1853538 c.-68_-66delGAAinsAAG upstream_gene_variant 0.88 linezolid
tsnR 1853552 c.-54C>G upstream_gene_variant 0.8 linezolid
tlyA 1917951 c.12T>C synonymous_variant 1.0 capreomycin
tlyA 1917966 c.27C>G synonymous_variant 1.0 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 1.0 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 1.0 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 1.0 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 1.0 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 1.0 capreomycin
tlyA 1918011 c.72G>C synonymous_variant 1.0 capreomycin
tlyA 1918035 c.96G>C synonymous_variant 1.0 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 1.0 capreomycin
tlyA 1918206 c.267G>C synonymous_variant 0.8 capreomycin
tlyA 1918212 c.273A>G synonymous_variant 0.92 capreomycin
tlyA 1918233 c.294A>G synonymous_variant 0.92 capreomycin
tlyA 1918236 c.297A>C synonymous_variant 0.91 capreomycin
tlyA 1918245 c.306C>T synonymous_variant 0.91 capreomycin Not assoc w R - Interim
tlyA 1918248 c.309T>C synonymous_variant 0.9 capreomycin
tlyA 1918251 c.312T>C synonymous_variant 0.9 capreomycin
tlyA 1918258 p.His107Glu missense_variant 0.9 capreomycin
tlyA 1918410 c.471C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
tlyA 1918420 p.Ala161Ser missense_variant 1.0 capreomycin
tlyA 1918442 p.Val168Ala missense_variant 1.0 capreomycin
tlyA 1918446 c.507A>T synonymous_variant 1.0 capreomycin
tlyA 1918452 c.513T>C synonymous_variant 1.0 capreomycin
tlyA 1918453 p.Ser172Asn missense_variant 1.0 capreomycin
tlyA 1918457 p.Arg173Pro missense_variant 1.0 capreomycin
tlyA 1918460 p.Asp174Gly missense_variant 1.0 capreomycin
tlyA 1918476 c.537A>C synonymous_variant 1.0 capreomycin
tlyA 1918477 p.Leu180Met missense_variant 1.0 capreomycin
bacA 2063574 c.1155C>G synonymous_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 0.77 kanamycin
capreomycin
streptomycin
amikacin
bacA 2063610 p.Ser373Ala missense_variant 0.79 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 0.86 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064981 c.-253G>C upstream_gene_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.92 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064996 c.-268G>C upstream_gene_variant 0.92 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101744 c.1299C>T synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101747 c.1296C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101753 c.1290C>G synonymous_variant 0.95 isoniazid
delamanid
ethionamide
ndh 2101762 c.1281C>T synonymous_variant 0.97 isoniazid
delamanid
ethionamide
ndh 2101771 c.1272T>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2101783 c.1260T>G synonymous_variant 0.97 isoniazid
delamanid
ethionamide
ndh 2101789 c.1254G>C synonymous_variant 0.98 isoniazid
delamanid
ethionamide
ndh 2101804 c.1239T>G synonymous_variant 0.96 isoniazid
delamanid
ethionamide
ndh 2101825 c.1218G>C synonymous_variant 0.94 isoniazid
delamanid
ethionamide
ndh 2101834 c.1209C>T synonymous_variant 0.93 isoniazid
delamanid Not assoc w R - Interim
ethionamide
ndh 2101838 p.Ala402Val missense_variant 0.92 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101858 c.1185T>C synonymous_variant 0.91 isoniazid
delamanid
ethionamide
ndh 2101873 c.1170T>C synonymous_variant 0.91 isoniazid
delamanid
ethionamide
ndh 2101888 p.Val385Leu missense_variant 0.88 isoniazid
delamanid
ethionamide
ndh 2101891 c.1152C>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.84 isoniazid
delamanid
ethionamide
ndh 2101912 c.1131G>T synonymous_variant 0.86 isoniazid
delamanid
ethionamide
ndh 2101915 c.1128T>C synonymous_variant 0.86 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101918 c.1123_1125delAGGinsCGC synonymous_variant 0.86 isoniazid
delamanid
ethionamide
ndh 2101921 c.1122G>A synonymous_variant 0.86 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101924 c.1119T>G synonymous_variant 0.9 isoniazid
delamanid
ethionamide
ndh 2102302 c.741G>C synonymous_variant 0.9 isoniazid
delamanid
ethionamide
ndh 2102305 c.738T>C synonymous_variant 0.8 isoniazid
delamanid
ethionamide
katG 2155029 c.1083C>G synonymous_variant 0.82 isoniazid
katG 2155032 c.1080T>C synonymous_variant 0.82 isoniazid Not assoc w R - Interim
katG 2155054 p.Tyr353Phe missense_variant 0.92 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.92 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.92 isoniazid
katG 2155065 c.1047C>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
katG 2155068 p.Ala348Gly missense_variant 0.92 isoniazid Uncertain significance
katG 2155071 c.1041T>G synonymous_variant 0.92 isoniazid
katG 2155081 p.Thr344Val missense_variant 0.8 isoniazid
katG 2155104 c.1008G>C synonymous_variant 0.9 isoniazid
katG 2155113 c.999C>G synonymous_variant 0.93 isoniazid
katG 2155119 c.993T>C synonymous_variant 0.93 isoniazid
katG 2155131 c.981A>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
katG 2155164 c.948C>T synonymous_variant 0.8 isoniazid
katG 2155167 c.945C>T synonymous_variant 0.8 isoniazid Not assoc w R - Interim
kasA 2517917 c.-198G>T upstream_gene_variant 0.97 isoniazid
kasA 2517926 c.-189G>A upstream_gene_variant 0.97 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.93 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.96 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.89 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.82 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.77 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.77 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.8 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.87 isoniazid
kasA 2518153 c.39C>T synonymous_variant 0.83 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.83 isoniazid
kasA 2518168 c.54C>T synonymous_variant 0.85 isoniazid
kasA 2518172 p.Thr20Ala missense_variant 0.85 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.84 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.87 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.86 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.83 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.83 isoniazid
kasA 2518261 c.147G>A synonymous_variant 0.87 isoniazid
kasA 2518268 p.Thr52Asp missense_variant 0.85 isoniazid
kasA 2518273 c.159G>A synonymous_variant 0.84 isoniazid
kasA 2518282 c.168A>G synonymous_variant 0.88 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.88 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.85 isoniazid
kasA 2518300 c.186T>G synonymous_variant 0.9 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518687 p.Asp191Glu missense_variant 1.0 isoniazid
kasA 2518699 c.585C>T synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518717 c.603C>G synonymous_variant 1.0 isoniazid
kasA 2518741 c.627G>A synonymous_variant 0.95 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.95 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.94 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.94 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.89 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.88 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.88 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.96 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.96 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.96 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.97 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.97 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.97 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.97 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518907 c.793T>C synonymous_variant 1.0 isoniazid
kasA 2518910 p.Leu266Met missense_variant 1.0 isoniazid
kasA 2518936 c.822C>T synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518951 c.837G>T synonymous_variant 1.0 isoniazid
kasA 2519146 c.1032C>G synonymous_variant 1.0 isoniazid
kasA 2519152 c.1038G>T synonymous_variant 0.93 isoniazid
kasA 2519161 c.1047G>A synonymous_variant 0.95 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.95 isoniazid
kasA 2519195 p.Thr361Ser missense_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519206 c.1092C>T synonymous_variant 1.0 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 1.0 isoniazid
kasA 2519221 c.1107G>A synonymous_variant 1.0 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 1.0 isoniazid
kasA 2519230 c.1116C>T synonymous_variant 1.0 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>G synonymous_variant 1.0 isoniazid
ahpC 2726579 c.387T>C synonymous_variant 1.0 isoniazid
ahpC 2726582 c.390G>C synonymous_variant 1.0 isoniazid
ahpC 2726585 c.393C>G synonymous_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 1.0 isoniazid
ahpC 2726639 c.447C>G synonymous_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.96 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.97 isoniazid
ahpC 2726657 c.465A>G synonymous_variant 0.97 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 0.96 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.96 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.96 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.91 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 0.89 isoniazid
ahpC 2726690 c.498C>T synonymous_variant 0.87 isoniazid
ahpC 2726693 c.501C>T synonymous_variant 0.83 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.83 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 0.83 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.7 isoniazid
folC 2746564 c.1035A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746585 c.1014G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746588 c.1011C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746599 p.Thr334Ala missense_variant 0.88 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746612 c.987C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 1.0 para-aminosalicylic_acid
folC 2746633 c.966C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747007 p.Ser198Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747083 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747101 c.498G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747120 p.Phe160Tyr missense_variant 0.95 para-aminosalicylic_acid
folC 2747122 c.477G>T synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747257 c.342G>A synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747263 c.336C>A synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747274 p.Ser109Ala missense_variant 0.85 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.79 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747334 c.265C>T synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747341 p.Val86Leu missense_variant 0.83 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.84 para-aminosalicylic_acid
folC 2747363 p.Ala79Val missense_variant 0.85 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.89 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747410 p.Ser63Gly missense_variant 0.82 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747443 c.156G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747464 c.135G>A synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782465 c.1578G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782495 c.1548C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.97 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.97 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.97 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.97 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>A synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782837 c.1206C>G synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 p.Ala394Ser missense_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782867 p.Ala392Gly missense_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782885 c.1158G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin