TB-Profiler result

Run: ERR294266
Summary

Run ID: ERR294266

Sample name:

Date: 2024-03-25T23:00:10.900526

Number of reads: 658523

Percentage reads mapped: 18.38

Median coverage: 5.0

Strain: lineage4.2;lineage4.8.1;lineage4.9

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.12
lineage4.2 Euro-American None 0.15
lineage4 Euro-American None 0.81
lineage4.8.1 Euro-American (mainly T) RD219 0.07
lineage4.9 Euro-American (H37Rv-like) None 0.8
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
p.Ile317Leu Mutation from literature
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.319_321delCACinsGG Assoc w R
c.481_483delGCTinsTC Assoc w R
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.391_393delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.538_540delCGTinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.97 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303321 c.391_393delGTTinsAC frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303468 c.538_540delCGTinsGG frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1918258 c.319_321delCACinsGG frameshift_variant&missense_variant 0.9 capreomycin Assoc w R
tlyA 1918420 c.481_483delGCTinsTC frameshift_variant&missense_variant 1.0 capreomycin Assoc w R
katG 2155108 p.Ile335Thr missense_variant 0.95 isoniazid Mutation from literature
katG 2155163 p.Ile317Leu missense_variant 0.8 isoniazid Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.97 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 0.94 isoniazid
dnaA 24 c.24C>T synonymous_variant 0.94 isoniazid
dnaA 30 c.30C>G synonymous_variant 0.94 isoniazid
dnaA 42 c.42C>T synonymous_variant 0.93 isoniazid
dnaA 54 c.54C>T synonymous_variant 0.9 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.67 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.67 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.67 isoniazid
dnaA 759 c.759C>T synonymous_variant 0.67 isoniazid
dnaA 762 c.762C>G synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 768 c.768C>T synonymous_variant 0.67 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.67 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.76 isoniazid
dnaA 789 c.789C>T synonymous_variant 0.88 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 798 c.798C>T synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 804 c.804G>C synonymous_variant 0.88 isoniazid
dnaA 805 c.805T>C synonymous_variant 0.88 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.94 isoniazid
dnaA 831 c.831A>G synonymous_variant 0.93 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.94 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.94 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.92 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.92 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.92 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.94 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.93 isoniazid
dnaA 909 c.909A>G synonymous_variant 0.91 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.9 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.86 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.86 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.88 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.88 isoniazid
dnaA 960 c.960C>G synonymous_variant 0.88 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.89 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.89 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.93 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.93 isoniazid
dnaA 993 c.993A>G synonymous_variant 0.93 isoniazid
dnaA 996 c.996A>T synonymous_variant 0.96 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1059 c.1059C>A synonymous_variant 0.98 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.98 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.97 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.97 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.96 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.96 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1134 c.1134G>C synonymous_variant 0.96 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.88 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 0.87 isoniazid
dnaA 1239 c.1239G>A synonymous_variant 0.81 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.86 isoniazid
dnaA 1260 c.1260C>T synonymous_variant 0.95 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.95 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.96 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.97 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.97 isoniazid
dnaA 1291 c.1291_1293delCTTinsTA frameshift_variant&missense_variant 0.97 isoniazid Uncertain significance
dnaA 1314 c.1314A>G synonymous_variant 0.94 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 1332 c.1332A>C synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.9 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 0.89 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.88 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 0.89 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.91 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.96 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.97 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
gyrB 6091 c.852G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.73 levofloxacin
moxifloxacin
gyrB 6127 c.888G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrB 6205 c.966C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6250 c.1011A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6259 p.Asp340Glu missense_variant 0.95 levofloxacin
moxifloxacin
gyrB 6266 p.Pro343Ala missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.97 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6440 p.Thr401Ser missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6445 p.Asp402Glu missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6452 p.Val405Thr missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 6466 c.-836G>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6481 c.1242G>A synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6484 c.-818A>G upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6511 c.-791A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6542 c.1303_1305delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6559 c.1320C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6625 c.-677G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6664 c.1425C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.79 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.85 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7186 c.-116C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7595 c.294C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7727 c.426G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7781 c.480G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7814 c.513C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8165 c.864C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8186 c.885G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8195 c.894C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8240 c.939C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsTG frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8345 c.1044C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8354 c.1053G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9083 c.1782G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.83 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>A synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9182 c.1881T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 0.77 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9206 c.1905C>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9209 c.1908G>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9266 c.1965C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9317 c.2016G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCA frameshift_variant&missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9392 c.2091C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13882 c.-326_-324delATCinsGG upstream_gene_variant 0.8 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.85 isoniazid
Rv0010c 13893 c.-335T>A upstream_gene_variant 0.8 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.85 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.85 isoniazid
fgd1 490803 c.21T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490857 c.75C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490875 c.93C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491112 c.330G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491172 c.390C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491623 p.Ala281Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491688 c.906A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491703 c.921C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491704 c.922C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575495 c.148C>T synonymous_variant 0.91 ethionamide
isoniazid
mshA 575500 c.153G>A synonymous_variant 0.92 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575524 c.177G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575527 c.180G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575530 c.183C>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575548 c.201C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575557 c.210C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575560 c.213C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575572 c.225T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575587 c.240C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575596 c.249C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575634 p.Ala96Val missense_variant 1.0 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575650 c.303G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575651 p.Arg102Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575656 c.309G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575658 p.Ala104Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575680 c.333C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575860 c.513G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575916 p.Asp190Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 0.92 ethionamide
isoniazid
mshA 576010 c.663C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 576011 c.664_666delAGGinsCA frameshift_variant&missense_variant 0.95 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576017 p.Val224Leu missense_variant 0.95 ethionamide
isoniazid
mshA 576026 c.679_681delCTTinsAC frameshift_variant&missense_variant 0.9 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576032 p.Gly229Asn missense_variant 0.9 ethionamide
isoniazid
mshA 576045 p.Ala233Gly missense_variant 0.95 ethionamide
isoniazid
mshA 576070 c.723T>C synonymous_variant 0.82 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGC upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-256delTCinsGT upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619678 c.-213G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619681 c.-210G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619899 c.9G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 619911 c.21C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619912 p.Val8Ile missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619929 c.39C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 619957 p.Val23Leu missense_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 619962 c.72G>C synonymous_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620291 p.Tyr134Phe missense_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620298 c.408G>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620301 c.411G>T synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.92 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620676 c.786C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620800 p.Val304Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656262 c.1209C>G synonymous_variant 0.8 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.83 ethionamide
Rv0565c 656271 c.1200C>T synonymous_variant 0.83 ethionamide
Rv0565c 656277 c.1194C>A synonymous_variant 0.85 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.85 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.85 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.85 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.94 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.94 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.94 ethionamide
Rv0565c 657201 c.270C>G synonymous_variant 0.95 ethionamide
Rv0565c 657219 p.Ala84Glu missense_variant 0.97 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.95 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.95 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.95 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 0.97 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.97 ethionamide
Rv0565c 657267 c.204G>T synonymous_variant 0.97 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 1.0 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 1.0 ethionamide
Rv0565c 657309 c.162C>G synonymous_variant 1.0 ethionamide
Rv0565c 657640 c.-170A>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731729 c.-201C>T upstream_gene_variant 0.92 isoniazid
hadA 731742 c.-188A>G upstream_gene_variant 0.93 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.94 isoniazid
hadA 731765 c.-165C>T upstream_gene_variant 0.96 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.96 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.96 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.97 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.97 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.94 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.88 isoniazid
hadA 732320 c.391_393delGAAinsAC frameshift_variant&missense_variant 0.88 isoniazid Uncertain significance
hadA 732325 c.396T>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
hadA 732328 p.Asp133Glu missense_variant 0.88 isoniazid Uncertain significance
hadA 732329 p.Leu134Thr missense_variant 0.88 isoniazid
hadA 732334 c.405G>C synonymous_variant 0.89 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.93 isoniazid
hadA 732367 c.438C>G synonymous_variant 0.95 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.96 isoniazid
hadA 732385 c.456A>G synonymous_variant 0.97 isoniazid
hadA 732389 p.Ser154Ala missense_variant 0.97 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.97 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.97 isoniazid
nusG 734053 c.-201A>T upstream_gene_variant 1.0 rifampicin
nusG 734078 c.-176C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734093 c.-161A>G upstream_gene_variant 0.95 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.95 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.95 rifampicin
nusG 734118 c.-136_-134delCTTinsTC upstream_gene_variant 0.95 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.97 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 0.96 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.96 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.96 rifampicin
nusG 734173 c.-81_-80delCCinsGA upstream_gene_variant 0.89 rifampicin
nusG 734175 c.-79_-78delGGinsCT upstream_gene_variant 0.89 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 0.89 rifampicin
nusG 734184 c.-70_-68delTTGinsCT upstream_gene_variant 0.89 rifampicin
nusG 734201 c.-53G>C upstream_gene_variant 0.96 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 0.96 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.96 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 0.95 rifampicin
nusG 734225 c.-29C>T upstream_gene_variant 0.95 rifampicin
nusG 734232 c.-22G>A upstream_gene_variant 0.94 rifampicin
nusG 734233 c.-21T>A upstream_gene_variant 0.94 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 0.94 rifampicin
nusG 734283 c.30G>C synonymous_variant 0.9 rifampicin
nusG 734415 c.162C>T synonymous_variant 0.93 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734448 c.195C>T synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734505 c.252G>A synonymous_variant 1.0 rifampicin
nusG 734520 c.267C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734844 c.591G>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734875 p.Val208Ile missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734905 c.652C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734943 c.690G>C synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Thr missense_variant 1.0 rifampicin
rpoB 759629 c.-178T>C upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.93 rifampicin Uncertain significance
rpoB 760088 c.282C>G synonymous_variant 0.95 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.98 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.97 rifampicin
rpoB 760172 c.366G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760356 c.550_552delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760403 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.92 rifampicin
rpoB 760754 c.948G>C synonymous_variant 1.0 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760796 c.990A>G synonymous_variant 0.96 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.95 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 0.95 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.9 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.91 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 0.9 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Thr missense_variant 0.91 rifampicin
rpoB 760877 c.1071G>T synonymous_variant 0.94 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.97 rifampicin
rpoB 760919 c.1113C>T synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>A synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 1.0 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>T synonymous_variant 0.97 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.91 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.93 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.97 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 1.0 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761240 c.1434C>T synonymous_variant 0.96 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>G synonymous_variant 0.95 rifampicin
rpoB 761282 c.1476C>T synonymous_variant 0.96 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.97 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761373 p.Val523Gln missense_variant 0.95 rifampicin
rpoB 761387 c.1581C>G synonymous_variant 0.94 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.82 rifampicin
rpoB 761414 c.1608A>T synonymous_variant 0.8 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.73 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.87 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.9 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.9 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.96 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>A synonymous_variant 0.94 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.92 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761816 c.2010C>G synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761955 p.Ile717Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762209 c.2403C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 0.93 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.93 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762347 c.2541T>C synonymous_variant 0.87 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.91 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 0.9 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.9 rifampicin
rpoC 762374 c.-996G>T upstream_gene_variant 0.95 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762494 c.-876G>A upstream_gene_variant 1.0 rifampicin
rpoC 762800 c.-570C>G upstream_gene_variant 1.0 rifampicin
rpoC 762812 c.-558C>A upstream_gene_variant 1.0 rifampicin
rpoB 762814 p.Met1003Arg missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762824 c.-546C>T upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762957 c.3151C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.98 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.98 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.96 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763199 c.-171G>T upstream_gene_variant 0.95 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.91 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.91 rifampicin
rpoC 763211 c.-159C>T upstream_gene_variant 0.91 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.9 rifampicin
rpoC 763238 c.-132T>G upstream_gene_variant 0.9 rifampicin
rpoC 763247 c.-123G>A upstream_gene_variant 0.87 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.88 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.82 rifampicin
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763405 c.36C>T synonymous_variant 0.96 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.97 rifampicin
rpoC 763420 c.51G>T synonymous_variant 0.97 rifampicin
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.97 rifampicin
rpoC 763435 c.66A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.97 rifampicin
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763711 c.342G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>A synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763778 p.Thr137Val missense_variant 1.0 rifampicin
rpoC 763781 p.Ser138Gly missense_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763852 c.483C>T synonymous_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>C synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763933 c.564C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764015 c.646C>T synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764212 c.843C>T synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764263 c.894G>C synonymous_variant 0.96 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.97 rifampicin
rpoC 764272 c.903G>T synonymous_variant 0.97 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.97 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.98 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.98 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.98 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>T synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>A synonymous_variant 0.97 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.96 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.97 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.96 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765065 c.1696C>T synonymous_variant 0.95 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.93 rifampicin
rpoC 765079 c.1710T>A synonymous_variant 0.93 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.93 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765350 p.Ala661Ser missense_variant 1.0 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.96 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.96 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.96 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.92 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765571 c.2202C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765578 c.2209C>T synonymous_variant 0.93 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 0.94 rifampicin
rpoC 765592 c.2223C>T synonymous_variant 0.94 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.96 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765640 c.2271A>G synonymous_variant 0.96 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 1.0 rifampicin
rpoC 765734 c.2365_2367delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.95 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.97 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.96 rifampicin
rpoC 766030 c.2661C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 0.97 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.87 rifampicin
rpoC 766080 c.2712delT frameshift_variant 0.88 rifampicin
rpoC 766084 c.2715_2716insG frameshift_variant 0.81 rifampicin
rpoC 766090 c.2721C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766096 c.2727G>C synonymous_variant 0.87 rifampicin
rpoC 766097 c.2728C>T synonymous_variant 0.87 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.89 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.83 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.81 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 0.81 rifampicin Uncertain significance
rpoC 766171 c.2802C>T synonymous_variant 0.82 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.82 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.72 rifampicin
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 0.62 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.79 rifampicin
rpoC 766280 c.2911_2913delAGCinsGT frameshift_variant&missense_variant 0.81 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 0.87 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.83 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.89 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.9 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.93 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.94 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.96 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.97 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.97 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766469 c.3100C>T synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.97 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.97 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.96 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.96 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.98 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.98 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.91 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.94 rifampicin
rpoC 767065 c.3696G>C synonymous_variant 0.91 rifampicin
rpoC 767066 c.3697C>T synonymous_variant 0.89 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.88 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 0.9 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.93 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.94 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>A synonymous_variant 1.0 rifampicin
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775864 p.Ala873Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 775874 c.2607C>A synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775880 p.Asn867Lys missense_variant 0.35 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.44 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.85 clofazimine
bedaquiline
mmpL5 775912 c.2569C>A synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 0.85 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>A synonymous_variant 0.55 clofazimine
bedaquiline
mmpL5 775927 c.2554C>T synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775937 c.2542_2544delGCGinsTC frameshift_variant&missense_variant 0.57 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775949 c.2532G>C synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.95 clofazimine
bedaquiline
mmpL5 775993 p.Glu830Lys missense_variant 0.77 clofazimine
bedaquiline
mmpL5 775997 c.2484T>G synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776003 c.2478C>T synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776008 p.His825Tyr missense_variant 0.77 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsCA frameshift_variant&missense_variant 0.77 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776024 c.2457G>C synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 776027 c.2454G>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776030 c.2451G>A synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 776056 p.Val809Leu missense_variant 0.83 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 776076 p.Ala802Phe missense_variant 0.83 clofazimine
bedaquiline
mmpL5 776084 c.2397C>A synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776093 c.2388C>A synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776102 c.2377_2379delATCinsGG frameshift_variant&missense_variant 0.71 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776120 c.2361C>T synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 777161 p.Gln440His missense_variant 0.73 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777185 c.1296G>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777191 c.1290C>A synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777212 c.1269C>G synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777626 c.855C>T synonymous_variant 0.67 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777629 c.852C>A synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 777640 c.841C>T synonymous_variant 0.73 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777647 c.834C>G synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 777678 p.Val268Thr missense_variant 0.73 clofazimine
bedaquiline
mmpL5 777680 c.801G>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777683 c.798C>A synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 777689 c.792C>T synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 777701 c.780C>A synonymous_variant 0.8 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.96 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.96 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.96 streptomycin
rpsL 781601 c.42C>T synonymous_variant 0.96 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.96 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.98 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.98 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.95 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.95 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.94 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.94 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.94 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.93 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.92 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.92 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.9 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.9 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.92 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 0.97 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.97 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.97 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.93 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.97 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.93 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.93 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.92 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.91 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.91 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.86 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.93 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.95 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.98 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.98 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.98 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.98 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.96 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.96 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.95 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.98 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94_-92delATCinsCT upstream_gene_variant 0.98 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.98 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800916 c.108A>C synonymous_variant 0.8 linezolid
rplC 800919 c.111C>G synonymous_variant 0.8 linezolid
rplC 800922 c.114C>G synonymous_variant 0.86 linezolid
rplC 800931 c.123G>C synonymous_variant 0.9 linezolid
rplC 800934 c.126C>G synonymous_variant 0.9 linezolid
rplC 800939 p.Arg44Leu missense_variant 0.91 linezolid Uncertain significance
rplC 800949 c.141T>C synonymous_variant 0.92 linezolid
rplC 800962 c.154C>T synonymous_variant 0.96 linezolid
rplC 800976 c.168G>A synonymous_variant 0.97 linezolid
rplC 801003 c.195G>C synonymous_variant 0.95 linezolid
rplC 801004 c.196_198delCTGinsGC frameshift_variant&missense_variant 0.95 linezolid
rplC 801009 c.201A>G synonymous_variant 0.95 linezolid Not assoc w R - Interim
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 0.92 linezolid
rplC 801174 c.366T>C synonymous_variant 0.92 linezolid
rplC 801183 c.375C>A synonymous_variant 0.93 linezolid
rplC 801195 c.387G>T synonymous_variant 0.93 linezolid
rplC 801198 c.390C>T synonymous_variant 0.93 linezolid
rplC 801207 c.399C>T synonymous_variant 0.94 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>T synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801285 c.477G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801300 c.492C>G synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 0.97 linezolid
rplC 801312 c.504G>T synonymous_variant 1.0 linezolid
rplC 801321 c.513C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801349 p.Leu181Val missense_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801363 c.555C>G synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801417 c.609T>C synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
Rv1129c 1253614 c.921C>T synonymous_variant 0.82 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253632 c.903T>C synonymous_variant 0.81 moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv1129c 1253635 c.900C>T synonymous_variant 0.88 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253638 c.897A>G synonymous_variant 0.88 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253641 c.892_894delCAGinsGA frameshift_variant&missense_variant 0.88 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1253653 c.882T>G synonymous_variant 0.89 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253665 c.868_870delCGCinsGG frameshift_variant&synonymous_variant 0.88 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1253683 c.852C>G synonymous_variant 0.95 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253686 c.849C>A synonymous_variant 0.96 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253707 c.828A>C synonymous_variant 0.92 moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv1129c 1253716 c.819G>C synonymous_variant 0.88 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253730 p.Ala269Ser missense_variant 0.92 moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1253743 p.Gln264Arg missense_variant 0.9 moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv1129c 1253746 c.787_789delGACinsCT frameshift_variant&missense_variant 0.9 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv1129c 1253749 c.786T>C synonymous_variant 0.9 moxifloxacin
levofloxacin
rifampicin
isoniazid
fbiC 1303233 c.303T>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303242 c.312T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303251 c.321C>T synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303272 c.342A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303281 c.351A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303284 c.354T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303285 p.Ser119Ala missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303288 p.Ser120Gly missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303292 p.Thr121Met missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303297 p.Met123Leu missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303302 c.372A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303314 c.384C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303464 c.534A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303665 c.735G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303680 c.750G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303722 c.792C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303740 c.810C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303896 c.966G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303938 c.1008C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303977 c.1047C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>C synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304805 c.1875G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304820 c.1890G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304913 c.1983G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Tyr missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305411 c.2481C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
sigE 1364835 c.423C>G synonymous_variant 0.73 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.8 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.89 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.9 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.9 pyrazinamide
sigE 1364875 c.463C>A synonymous_variant 0.9 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.9 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.95 pyrazinamide Uncertain significance
sigE 1364892 c.480C>G synonymous_variant 0.95 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.96 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 1.0 pyrazinamide
sigE 1364954 p.Arg181His missense_variant 1.0 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 1.0 pyrazinamide
sigE 1364962 c.550_552delCCTinsGC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364976 c.564T>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.89 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.88 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.9 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.91 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.87 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 0.86 pyrazinamide
sigE 1365078 c.666C>G synonymous_variant 0.86 pyrazinamide
sigE 1365081 c.669G>C synonymous_variant 0.84 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.84 pyrazinamide
sigE 1365087 c.675A>G synonymous_variant 0.84 pyrazinamide
sigE 1365096 c.684G>A synonymous_variant 0.76 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.75 pyrazinamide
sigE 1365111 c.699C>T synonymous_variant 0.71 pyrazinamide
sigE 1365117 c.705A>T synonymous_variant 0.73 pyrazinamide
sigE 1365118 c.706C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
embR 1416643 c.705G>C synonymous_variant 1.0 ethambutol
embR 1416649 c.699A>G synonymous_variant 1.0 ethambutol
embR 1416664 c.684T>C synonymous_variant 1.0 ethambutol
embR 1416667 c.681C>G synonymous_variant 1.0 ethambutol
embR 1416671 p.Gly226Ala missense_variant 1.0 ethambutol
embR 1416679 c.669T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embR 1416691 c.657C>T synonymous_variant 1.0 ethambutol
embR 1416696 p.Ser218Thr missense_variant 1.0 ethambutol
embR 1416697 c.651C>G synonymous_variant 1.0 ethambutol
embR 1416717 c.631C>T synonymous_variant 0.94 ethambutol
embR 1416721 c.625_627delACAinsGG frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
atpE 1461197 c.153A>G synonymous_variant 0.91 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.83 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.77 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.71 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.71 bedaquiline
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 0.83 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.84 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.84 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.74 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 0.71 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474108 n.451C>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474156 n.499G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629C>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474291 n.635_651delTTCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474311 n.654_655insAA non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.73 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
inhA 1673601 c.-601G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 1.0 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.91 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.91 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673697 c.-505G>A upstream_gene_variant 0.89 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.9 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
fabG1 1674083 p.Ala215Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674120 c.-82G>A upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.96 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.96 ethionamide
isoniazid
inhA 1674147 c.-55C>T upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1674150 c.-52C>A upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1674156 c.-46C>T upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.86 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674504 c.303C>G synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674531 c.330C>T synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674549 c.348G>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 0.94 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674703 c.502T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 0.95 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674745 p.Tyr182Ala missense_variant 0.94 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.92 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674774 c.573A>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674837 c.636C>T synonymous_variant 0.94 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674846 p.Ile215Met missense_variant 0.95 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.95 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674930 c.729C>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833271 c.-271G>A upstream_gene_variant 0.75 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 0.75 pyrazinamide
rpsA 1833280 c.-262G>A upstream_gene_variant 0.79 pyrazinamide
rpsA 1833283 c.-259C>A upstream_gene_variant 0.73 pyrazinamide
rpsA 1833288 c.-254T>C upstream_gene_variant 0.85 pyrazinamide
rpsA 1833305 c.-237G>A upstream_gene_variant 0.85 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.75 pyrazinamide
rpsA 1833315 c.-227C>A upstream_gene_variant 0.83 pyrazinamide
rpsA 1833317 c.-225_-223delCTCinsTG upstream_gene_variant 0.83 pyrazinamide
rpsA 1833325 c.-217C>G upstream_gene_variant 0.83 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.95 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 0.97 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.97 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1833782 p.Ser81Thr missense_variant 0.96 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.94 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.93 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833883 c.342C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 0.96 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.97 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTG frameshift_variant&stop_gained 0.97 pyrazinamide Uncertain significance
rpsA 1834279 c.738C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.93 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834351 c.810G>A synonymous_variant 0.95 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834405 c.864C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 0.89 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.95 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834726 c.1185C>T synonymous_variant 0.88 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.96 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.96 linezolid
tsnR 1853394 c.-212_-210delCTCinsGCG upstream_gene_variant 0.91 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.93 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.92 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.88 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.88 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.89 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.89 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.89 linezolid
tsnR 1853468 c.-138C>T upstream_gene_variant 0.91 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.93 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.93 linezolid
tsnR 1853495 c.-111G>A upstream_gene_variant 0.93 linezolid
tsnR 1853516 c.-90C>T upstream_gene_variant 0.87 linezolid
tsnR 1853538 c.-68_-66delGAAinsAG upstream_gene_variant 0.88 linezolid
tsnR 1853552 c.-54C>G upstream_gene_variant 0.8 linezolid
tlyA 1917951 c.12T>C synonymous_variant 1.0 capreomycin
tlyA 1917966 c.27C>G synonymous_variant 1.0 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 1.0 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 1.0 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 1.0 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 1.0 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 1.0 capreomycin
tlyA 1918011 c.72G>C synonymous_variant 1.0 capreomycin
tlyA 1918035 c.96G>C synonymous_variant 1.0 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 1.0 capreomycin
tlyA 1918206 c.267G>C synonymous_variant 0.8 capreomycin
tlyA 1918212 c.273A>G synonymous_variant 0.92 capreomycin
tlyA 1918233 c.294A>G synonymous_variant 0.92 capreomycin
tlyA 1918236 c.297A>C synonymous_variant 0.91 capreomycin
tlyA 1918245 c.306C>T synonymous_variant 0.91 capreomycin Not assoc w R - Interim
tlyA 1918248 c.309T>C synonymous_variant 0.9 capreomycin
tlyA 1918251 c.312T>C synonymous_variant 0.9 capreomycin
tlyA 1918410 c.471C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
tlyA 1918442 p.Val168Ala missense_variant 1.0 capreomycin
tlyA 1918446 c.507A>T synonymous_variant 1.0 capreomycin
tlyA 1918452 c.513T>C synonymous_variant 1.0 capreomycin
tlyA 1918453 p.Ser172Asn missense_variant 1.0 capreomycin
tlyA 1918457 p.Arg173Pro missense_variant 1.0 capreomycin
tlyA 1918460 p.Asp174Gly missense_variant 1.0 capreomycin
tlyA 1918476 c.537A>C synonymous_variant 1.0 capreomycin
tlyA 1918477 p.Leu180Met missense_variant 1.0 capreomycin
bacA 2063574 c.1155C>G synonymous_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063588 c.1141T>C synonymous_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
bacA 2063610 c.1117_1119delTCCinsGG frameshift_variant&missense_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064969 c.-241T>C upstream_gene_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064981 c.-253G>C upstream_gene_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.93 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064996 c.-268G>C upstream_gene_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101744 c.1299C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101747 c.1296C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101753 c.1290C>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101762 c.1281C>T synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101789 c.1254G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101825 c.1218G>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2101834 c.1209C>T synonymous_variant 0.93 ethionamide
delamanid Not assoc w R - Interim
isoniazid
ndh 2101838 p.Ala402Val missense_variant 0.92 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 c.1185T>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 0.88 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 0.88 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101894 c.1149T>C synonymous_variant 0.84 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>T synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2101915 c.1128T>C synonymous_variant 0.86 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101918 c.1123_1125delAGGinsCC frameshift_variant&missense_variant 0.86 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101921 c.1122G>A synonymous_variant 0.86 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101924 c.1119T>G synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102302 c.741G>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>C synonymous_variant 0.8 ethionamide
delamanid
isoniazid
katG 2155029 c.1083C>G synonymous_variant 0.82 isoniazid
katG 2155032 c.1080T>C synonymous_variant 0.82 isoniazid Not assoc w R - Interim
katG 2155054 p.Tyr353Phe missense_variant 0.92 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.92 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.92 isoniazid
katG 2155065 c.1047C>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
katG 2155068 p.Ala348Gly missense_variant 0.92 isoniazid Uncertain significance
katG 2155071 c.1041T>G synonymous_variant 0.92 isoniazid
katG 2155081 p.Thr344Val missense_variant 0.8 isoniazid
katG 2155104 c.1008G>C synonymous_variant 0.9 isoniazid
katG 2155113 c.999C>G synonymous_variant 0.93 isoniazid
katG 2155119 c.993T>C synonymous_variant 0.93 isoniazid
katG 2155131 c.981A>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
katG 2155164 c.948C>T synonymous_variant 0.8 isoniazid
katG 2155167 c.945C>T synonymous_variant 0.8 isoniazid Not assoc w R - Interim
kasA 2517917 c.-198G>T upstream_gene_variant 0.97 isoniazid
kasA 2517926 c.-189G>A upstream_gene_variant 0.97 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.93 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.96 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.89 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.82 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.77 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.77 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.8 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.87 isoniazid
kasA 2518153 c.39C>T synonymous_variant 0.83 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.83 isoniazid
kasA 2518168 c.54C>T synonymous_variant 0.85 isoniazid
kasA 2518172 c.58_60delACAinsGG frameshift_variant&missense_variant 0.85 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.84 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.87 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.86 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.83 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.83 isoniazid
kasA 2518261 c.147G>A synonymous_variant 0.87 isoniazid
kasA 2518268 p.Thr52Asp missense_variant 0.85 isoniazid
kasA 2518273 c.159G>A synonymous_variant 0.84 isoniazid
kasA 2518282 c.168A>G synonymous_variant 0.88 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.88 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.85 isoniazid
kasA 2518300 c.186T>G synonymous_variant 0.9 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518687 p.Asp191Glu missense_variant 1.0 isoniazid
kasA 2518699 c.585C>T synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518717 c.603C>G synonymous_variant 1.0 isoniazid
kasA 2518741 c.627G>A synonymous_variant 0.95 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.95 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.94 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.94 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.89 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.88 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.88 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.96 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.96 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.96 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.97 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.97 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.97 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.97 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518907 c.793T>C synonymous_variant 1.0 isoniazid
kasA 2518910 p.Leu266Met missense_variant 1.0 isoniazid
kasA 2518936 c.822C>T synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518951 c.837G>T synonymous_variant 1.0 isoniazid
kasA 2519146 c.1032C>G synonymous_variant 1.0 isoniazid
kasA 2519152 c.1038G>T synonymous_variant 0.93 isoniazid
kasA 2519161 c.1047G>A synonymous_variant 0.95 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.95 isoniazid
kasA 2519195 c.1081_1083delACGinsTA frameshift_variant&stop_gained 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519206 c.1092C>T synonymous_variant 1.0 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 1.0 isoniazid
kasA 2519221 c.1107G>A synonymous_variant 1.0 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 1.0 isoniazid
kasA 2519230 c.1116C>T synonymous_variant 1.0 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>G synonymous_variant 1.0 isoniazid
ahpC 2726579 c.387T>C synonymous_variant 1.0 isoniazid
ahpC 2726582 c.390G>C synonymous_variant 1.0 isoniazid
ahpC 2726585 c.393C>G synonymous_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 1.0 isoniazid
ahpC 2726639 c.447C>G synonymous_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.96 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.97 isoniazid
ahpC 2726657 c.465A>G synonymous_variant 0.97 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 0.96 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.96 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.96 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.91 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 0.89 isoniazid
ahpC 2726690 c.498C>T synonymous_variant 0.87 isoniazid
ahpC 2726693 c.501C>T synonymous_variant 0.83 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.83 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 0.83 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.7 isoniazid
folC 2746564 c.1035A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746585 c.1014G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746588 c.1011C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746599 p.Thr334Ala missense_variant 0.88 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746612 c.987C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 1.0 para-aminosalicylic_acid
folC 2746633 c.966C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747007 p.Ser198Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747083 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747101 c.498G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747120 p.Phe160Tyr missense_variant 0.95 para-aminosalicylic_acid
folC 2747122 c.477G>T synonymous_variant 0.95 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747257 c.342G>A synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747263 c.336C>A synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747274 p.Ser109Ala missense_variant 0.85 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.79 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.79 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747334 c.265C>T synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsTG frameshift_variant&synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.84 para-aminosalicylic_acid
folC 2747363 p.Ala79Val missense_variant 0.85 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.89 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747410 c.187_189delAGCinsGT frameshift_variant&synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747443 c.156G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747464 c.135G>A synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782465 c.1578G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 c.1548C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>A synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.91 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782837 c.1206C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1180_1182delGCTinsTG frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782864 c.1179T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782867 p.Ala392Gly missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782876 c.1167G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782885 c.1158G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783299 c.744A>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783398 c.645C>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.616_618delCCCinsGG frameshift_variant&missense_variant 0.97 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783449 c.594C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783458 c.585G>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783470 c.573C>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783578 c.465G>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783650 c.393C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783659 p.Glu128Asp missense_variant 0.98 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783674 c.369T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783773 c.270A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783818 c.225G>A synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783842 c.201C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.169_171delCCGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783967 c.76T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784480 c.-438G>T upstream_gene_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784489 c.-447C>A upstream_gene_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784492 c.-450C>G upstream_gene_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-461_-459delGGTinsAC upstream_gene_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784510 c.-470_-468delAGCinsGT upstream_gene_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784514 c.-472C>A upstream_gene_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784519 c.-477G>C upstream_gene_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2997257 c.519C>G synonymous_variant 1.0 capreomycin
Rv2681 2997263 c.525A>G synonymous_variant 1.0 capreomycin
Rv2681 2997267 c.529_531delTCGinsAC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997271 p.Ala178Glu missense_variant 1.0 capreomycin
Rv2681 2997278 c.540G>C synonymous_variant 1.0 capreomycin
Rv2681 2997291 c.553_555delTTGinsCC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997308 c.570C>G synonymous_variant 1.0 capreomycin
Rv2681 2997309 p.Ile191Val missense_variant 1.0 capreomycin
Rv2681 2997317 c.579A>G synonymous_variant 1.0 capreomycin
Rv2752c 3064902 c.1290C>T synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064932 c.1260T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 0.9 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064950 c.1242C>A synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064956 p.Ser412Thr missense_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064968 c.1224G>A synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064989 c.1203G>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064995 c.1197C>T synonymous_variant 0.76 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>C synonymous_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065397 c.795G>C synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>G synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065403 c.789C>G synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065421 c.771G>A synonymous_variant 0.57 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065429 c.763T>C synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065430 c.762A>T synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065451 c.741G>A synonymous_variant 0.69 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>G synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065466 c.726G>C synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065659 p.Pro178Leu missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065664 p.Leu176Thr missense_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065886 c.306C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065901 c.291A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065947 p.Gly82Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065949 c.243C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065952 c.240C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065957 c.235T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065958 c.234G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065982 c.210G>A synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.9 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066000 c.190_192delATGinsCA frameshift_variant&missense_variant 0.89 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066006 c.186G>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066093 c.99T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066129 c.63G>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066135 c.57C>T synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066138 c.54C>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066243 c.-52C>T upstream_gene_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066255 c.-64C>T upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066260 c.-69T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066276 c.-85G>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066279 c.-88A>G upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066285 c.-94C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066294 c.-103C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066300 c.-109G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066306 c.-115T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066336 c.-145C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066350 c.-159T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066357 c.-166G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066360 c.-169T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066395 c.-204G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066398 c.-207G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066399 c.-210_-208delATTinsGA upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066420 c.-229C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066425 c.-234A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066429 c.-238G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066436 c.-246_-245delGGinsAA upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066456 c.-265A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-274G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-291_-289delGCCinsTG upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066495 c.-304C>T upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-311_-310delCGinsTC upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066504 c.-314_-313delCCinsGA upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066534 c.-343G>T upstream_gene_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066560 c.-369C>T upstream_gene_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>A upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066707 c.-516A>G upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066747 c.-558_-556delCAAinsATC upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066756 c.-565G>C upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066769 c.-578A>G upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066792 c.-601G>C upstream_gene_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066828 c.-637C>G upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066835 c.-645_-644delCGinsAA upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066864 c.-673C>G upstream_gene_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>G upstream_gene_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066891 c.-700G>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066897 c.-706G>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066905 c.-714T>C upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066906 c.-715C>G upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066912 c.-721G>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066927 c.-736A>G upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066933 c.-743_-742delGGinsAC upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066966 c.-775C>A upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066975 c.-784G>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>C upstream_gene_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067382 c.564C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067391 c.555G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067436 c.510C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067442 c.504C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067463 c.481_483delATCinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067481 c.465C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067670 c.276G>A synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067679 p.Cys89Leu missense_variant 0.88 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067718 c.226_228delGCCinsTG frameshift_variant&missense_variant 0.81 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.8 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.79 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067808 c.138C>T synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067844 c.102G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.95 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 0.95 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073896 c.576C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3074318 p.Phe52Leu missense_variant 0.95 para-aminosalicylic_acid
thyA 3074319 c.153T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074331 c.141C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074337 c.135C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074343 c.129G>A synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074355 c.117G>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074372 p.Met34Leu missense_variant 0.93 para-aminosalicylic_acid
thyA 3074377 p.Gln32Arg missense_variant 0.93 para-aminosalicylic_acid
ald 3087290 c.471T>C synonymous_variant 0.82 cycloserine
ald 3087293 c.474G>C synonymous_variant 0.82 cycloserine
ald 3087311 c.492C>G synonymous_variant 0.83 cycloserine
ald 3087318 c.499_501delGAAinsAG frameshift_variant&missense_variant 0.79 cycloserine
ald 3087350 c.531C>A synonymous_variant 0.79 cycloserine
ald 3087353 c.534C>G synonymous_variant 0.79 cycloserine
lpqB 3624646 c.265T>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624650 c.261G>A synonymous_variant 0.86 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624680 c.231T>A synonymous_variant 0.87 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 0.85 bedaquiline
rifampicin Uncertain significance
lpqB 3624701 c.210T>G synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCC frameshift_variant&missense_variant 0.74 bedaquiline
rifampicin Uncertain significance
lpqB 3624760 c.151C>T synonymous_variant 0.72 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 0.65 bedaquiline
rifampicin
lpqB 3624779 c.132G>C synonymous_variant 0.67 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 0.67 bedaquiline
rifampicin
lpqB 3624785 c.126G>A synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624788 c.123A>G synonymous_variant 0.67 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625057 c.-147C>T upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625095 p.Glu507Gln missense_variant 0.81 bedaquiline
rifampicin
lpqB 3625096 c.-186C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625105 c.1509C>T synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625117 c.-207T>G upstream_gene_variant 0.78 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625135 c.-225A>C upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625138 c.-228C>A upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.77 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625174 c.-264C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625258 c.-348G>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625298 p.Ala439Val missense_variant 0.94 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.92 bedaquiline
rifampicin
lpqB 3625327 c.-417A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625372 c.-462A>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 0.76 bedaquiline
rifampicin
lpqB 3625381 c.-471T>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3625386 p.Ala410Pro missense_variant 0.72 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3625407 p.Gln403Glu missense_variant 0.5 bedaquiline
rifampicin
mtrB 3625408 c.1206G>A synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625687 c.927G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625693 c.-783G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625708 c.906C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625723 c.-813C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625744 c.870G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.98 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.850_852delCGAinsAG frameshift_variant&missense_variant 0.98 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625771 c.843C>T synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625807 c.-897C>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625819 c.795G>A synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625837 c.-927C>A upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625888 c.-978G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625897 c.-987G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625906 c.-996G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625909 c.-999T>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625915 c.699G>A synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3625924 c.690G>C synonymous_variant 0.94 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.93 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 0.93 bedaquiline
rifampicin
mtrB 3626642 c.-29G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626647 c.-34A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626650 c.-37A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626684 c.-71G>T upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626765 c.585C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626777 c.573C>T synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626780 c.-167T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626792 c.558G>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626819 c.-206G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3626861 c.489C>A synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626866 c.-253T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626909 c.441C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626924 c.-311G>T upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627113 c.-500C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627122 c.-509T>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3627170 c.-557C>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627175 c.175C>T synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627181 c.-568T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3627185 c.163_165delTTGinsCT frameshift_variant&missense_variant 0.78 bedaquiline
rifampicin
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.78 bedaquiline
rifampicin
mtrB 3627197 c.-584T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627233 c.-620T>G upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3627239 c.111C>T synonymous_variant 0.84 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627242 c.108C>T synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3627278 c.-665G>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3627296 c.-683T>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCC frameshift_variant&missense_variant 0.9 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.91 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3627375 c.-762C>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3627377 c.-764G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3627380 c.-767T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3627861 c.-512C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
fbiB 3640914 c.-621C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642686 c.1152G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642692 c.1158C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642711 p.Leu393Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642752 c.1218C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642753 c.1219C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642763 p.Asp410Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642773 p.Asp413Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
alr 3841248 p.His58Ser missense_variant 0.9 cycloserine
rpoA 3877492 p.Gln339Ala missense_variant 0.9 rifampicin
rpoA 3877494 p.Glu338Asp missense_variant 0.9 rifampicin Uncertain significance
rpoA 3877503 c.1005G>T synonymous_variant 0.93 rifampicin
rpoA 3877506 c.1002C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877515 c.993G>C synonymous_variant 0.96 rifampicin
rpoA 3877524 c.984C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877554 c.954G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 1.0 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.95 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 0.94 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.94 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877742 c.766C>T synonymous_variant 0.94 rifampicin
rpoA 3877752 c.756C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>A synonymous_variant 1.0 rifampicin
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.95 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.93 rifampicin
rpoA 3877869 c.639G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.95 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.95 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.95 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.96 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.97 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.86 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.86 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.86 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.86 rifampicin
rpoA 3878043 c.465G>T synonymous_variant 0.84 rifampicin
rpoA 3878049 c.459G>T synonymous_variant 0.83 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.8 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.77 rifampicin
rpoA 3878064 c.444G>A synonymous_variant 0.77 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.75 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.75 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 0.75 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.75 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878103 c.405A>G synonymous_variant 0.86 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.84 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.89 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.92 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.97 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 0.95 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.95 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.9 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.93 rifampicin
rpoA 3878262 c.244_246delAGCinsGT frameshift_variant&synonymous_variant 0.94 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 0.97 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.98 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>C synonymous_variant 0.97 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.97 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878406 c.102G>T synonymous_variant 0.93 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.92 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.93 rifampicin
rpoA 3878433 c.75G>A synonymous_variant 0.94 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.94 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.91 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.92 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.91 rifampicin
rpoA 3878471 p.Val13Ile missense_variant 0.92 rifampicin
rpoA 3878472 c.36C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878478 c.30C>G synonymous_variant 0.92 rifampicin
rpoA 3878499 c.9C>T synonymous_variant 0.95 rifampicin
rpoA 3878507 c.-1_1insC upstream_gene_variant 0.9 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878758 c.-251G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878769 c.-262C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878818 c.-311G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878837 c.-331_-330delAAinsGG upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.97 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3878938 c.-431T>C upstream_gene_variant 0.96 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.96 rifampicin Uncertain significance
rpoA 3878953 c.-446C>T upstream_gene_variant 0.95 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 0.95 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.96 rifampicin
rpoA 3879006 c.-499A>C upstream_gene_variant 0.95 rifampicin
rpoA 3879013 c.-508_-506delGAAinsAC upstream_gene_variant 0.88 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.87 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.93 rifampicin
rpoA 3879033 c.-526C>G upstream_gene_variant 0.93 rifampicin
rpoA 3879034 c.-527G>C upstream_gene_variant 0.93 rifampicin
rpoA 3879040 c.-535_-533delGTGinsACT upstream_gene_variant 0.93 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.97 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879117 c.-610C>A upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879169 c.-662G>A upstream_gene_variant 0.98 rifampicin
rpoA 3879172 c.-665C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879238 c.-731C>T upstream_gene_variant 1.0 rifampicin
clpC1 4038248 c.2457C>G synonymous_variant 0.87 pyrazinamide
clpC1 4038254 c.2451G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038271 p.Pro812Thr missense_variant 0.96 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038299 c.2406C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038308 c.2397G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038317 c.2388G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038428 c.2277G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038461 c.2244G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Thr missense_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038575 c.2130C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038782 c.1923G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.87 pyrazinamide
clpC1 4038899 c.1806C>G synonymous_variant 0.88 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038911 c.1794G>A synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038914 c.1791G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.86 pyrazinamide
clpC1 4038929 c.1776G>T synonymous_variant 0.87 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.85 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.89 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.89 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039094 c.1611C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039140 p.Glu522Val missense_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039160 c.1545C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039169 p.Glu512Asp missense_variant 0.96 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039199 c.1506C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039202 c.1503G>A synonymous_variant 0.89 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039319 c.1384_1386delGCTinsAC frameshift_variant&missense_variant 0.92 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 0.91 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.91 pyrazinamide
clpC1 4039331 c.1374C>A synonymous_variant 0.91 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.75 pyrazinamide
clpC1 4039343 c.1362G>A synonymous_variant 0.85 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039361 c.1344C>A synonymous_variant 0.91 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.84 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.9 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.91 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039439 c.1266C>A synonymous_variant 0.95 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039562 c.1143C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039574 c.1129_1131delGCGinsTT frameshift_variant&missense_variant 0.95 pyrazinamide
clpC1 4039589 c.1116G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039736 c.969C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.96 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039838 c.867G>A synonymous_variant 0.96 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039922 c.783C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.95 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.98 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040138 c.567G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040180 c.525C>G synonymous_variant 0.92 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.93 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040549 c.154_156delTTGinsCT frameshift_variant&missense_variant 0.97 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>T synonymous_variant 0.87 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.98 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.98 pyrazinamide
clpC1 4040657 c.48T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040669 c.36C>G synonymous_variant 0.98 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.98 pyrazinamide
clpC1 4040705 c.-1G>C upstream_gene_variant 0.97 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.97 pyrazinamide
clpC1 4041008 c.-304C>G upstream_gene_variant 0.7 pyrazinamide
glpK 4138472 c.1284G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>T synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138518 p.Glu413Ala missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138553 c.1203C>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>T synonymous_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138625 c.1131G>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138628 c.1128T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138667 c.1089G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138682 c.1074C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138697 c.1059C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138702 p.Gln352Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138713 p.Ala348Trp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138715 c.1041G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139053 p.Ala235Ser missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139060 c.696A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139067 p.Glu230Ala missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139069 c.687C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139078 c.678C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139081 c.675G>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139084 c.672T>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139087 c.669A>T synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139096 p.Leu220Phe missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139099 c.657G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139104 c.652T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139129 c.627G>A synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139143 c.613T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139159 c.597C>T synonymous_variant 0.87 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139165 c.591A>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139561 c.195G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139575 p.Val61Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139579 c.177C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139585 c.171G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 p.Arg52Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139633 c.123C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139636 c.120C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139639 c.117G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139648 c.108T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139653 p.His35Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139663 c.93C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139672 c.84C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139681 c.75C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4239129 c.-734C>T upstream_gene_variant 1.0 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 0.8 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 1.0 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 1.0 ethambutol
embC 4239167 c.-696G>C upstream_gene_variant 1.0 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 1.0 ethambutol
embC 4239185 c.-678G>C upstream_gene_variant 1.0 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.8 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4240759 c.897C>G synonymous_variant 0.97 ethambutol
embC 4240777 c.915G>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.94 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.94 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.96 ethambutol
embC 4240811 c.949_951delTTCinsCG frameshift_variant&missense_variant 0.95 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.92 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.92 ethambutol
embC 4240853 c.991C>T synonymous_variant 0.86 ethambutol Not assoc w R - Interim
embC 4240859 c.997C>T synonymous_variant 0.82 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.91 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.9 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.93 ethambutol
embC 4241158 c.1296T>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4241161 c.1299C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.92 ethambutol
embC 4241182 c.1320G>C synonymous_variant 1.0 ethambutol
embC 4241185 c.1323G>C synonymous_variant 1.0 ethambutol
embC 4241191 c.1329C>T synonymous_variant 1.0 ethambutol
embC 4241194 c.1332C>G synonymous_variant 1.0 ethambutol
embC 4241197 c.1335G>C synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embC 4241206 c.1344G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241219 p.Ile453Val missense_variant 1.0 ethambutol
embC 4241545 c.1683T>G synonymous_variant 0.82 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.86 ethambutol
embC 4241560 c.1698C>G synonymous_variant 0.87 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.89 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.94 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.94 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.97 ethambutol
embC 4241617 c.1755G>A synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4241623 c.1761C>G synonymous_variant 0.97 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.93 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.96 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>T synonymous_variant 0.89 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.92 ethambutol
embA 4242739 c.-494C>G upstream_gene_variant 0.94 ethambutol
embC 4242740 p.Leu960Val missense_variant 0.94 ethambutol
embA 4242745 c.-488A>C upstream_gene_variant 0.94 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.94 ethambutol
embC 4242762 p.Arg967Gln missense_variant 0.95 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.95 ethambutol
embC 4242779 c.2917_2919delAACinsCG frameshift_variant&missense_variant 0.96 ethambutol
embC 4242789 c.2927_2928insTT frameshift_variant 1.0 ethambutol
embC 4242793 c.2933_2934delCG frameshift_variant 1.0 ethambutol
embA 4242818 c.-415C>T upstream_gene_variant 1.0 ethambutol
embA 4242826 c.-407G>T upstream_gene_variant 0.97 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 0.97 ethambutol
embC 4242835 c.2973C>T synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embA 4242838 c.-395C>G upstream_gene_variant 0.97 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.97 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.97 ethambutol
embA 4242859 c.-374C>T upstream_gene_variant 0.97 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.97 ethambutol
embA 4242871 c.-362C>T upstream_gene_variant 0.97 ethambutol
embC 4242877 c.3015G>A synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4242880 c.-353A>C upstream_gene_variant 0.97 ethambutol
embA 4242892 c.-341G>C upstream_gene_variant 0.97 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.96 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 0.94 ethambutol
embC 4242941 p.His1027Asn missense_variant 0.94 ethambutol
embA 4242946 c.-287T>C upstream_gene_variant 0.93 ethambutol
embC 4242958 c.3096G>A synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embA 4244372 c.1140T>C synonymous_variant 1.0 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.85 ethambutol
embA 4244886 c.1654C>T synonymous_variant 0.85 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.92 ethambutol
embA 4244904 p.Val558Leu missense_variant 0.92 ethambutol Uncertain significance
embA 4244909 c.1677C>G synonymous_variant 0.92 ethambutol
embA 4244921 c.1689C>G synonymous_variant 0.87 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.86 ethambutol
embA 4244936 c.1704C>G synonymous_variant 0.86 ethambutol
embA 4245059 c.1827G>C synonymous_variant 0.79 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.79 ethambutol
embA 4245063 c.1831C>T synonymous_variant 0.79 ethambutol
embA 4245078 p.Trp616Val missense_variant 0.73 ethambutol
embA 4245083 c.1851A>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embA 4245086 c.1854C>G synonymous_variant 0.86 ethambutol
embA 4245093 p.Ile621Val missense_variant 0.94 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 0.94 ethambutol
embA 4245164 c.1932C>T synonymous_variant 0.83 ethambutol
embA 4245174 p.Ser648Thr missense_variant 0.87 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.82 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.86 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.8 ethambutol
embA 4245198 p.Leu656Ala missense_variant 0.8 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.79 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.76 ethambutol
embA 4245222 p.Tyr664Leu missense_variant 0.81 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.94 ethambutol
embA 4246336 p.Ala1035Val missense_variant 0.9 ethambutol
embA 4246338 p.Leu1036Met missense_variant 0.9 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 0.95 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.95 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
embB 4246364 c.-150G>C upstream_gene_variant 0.94 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.93 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.93 ethambutol
embB 4246403 c.-111G>C upstream_gene_variant 0.87 ethambutol
embB 4247365 c.852A>C synonymous_variant 0.87 ethambutol
embB 4247375 p.Leu288Val missense_variant 0.9 ethambutol
embB 4247380 c.867C>G synonymous_variant 0.91 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.92 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.93 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.94 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.94 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247446 c.933C>T synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.97 ethambutol
embB 4247494 c.981G>A synonymous_variant 0.97 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.96 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.96 ethambutol
embB 4247503 c.990C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4247506 c.993C>T synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4247512 c.999T>C synonymous_variant 0.97 ethambutol
embB 4247519 c.1006C>T synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247548 c.1035C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>A synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247576 c.1063C>T synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Ile missense_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>C synonymous_variant 1.0 ethambutol
embB 4248064 c.1551G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>A synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248139 c.1626C>A synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248161 c.1648C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248173 p.Val554Leu missense_variant 1.0 ethambutol
embB 4248199 c.1686A>C synonymous_variant 1.0 ethambutol
embB 4248200 p.Ile563Val missense_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248211 c.1698G>C synonymous_variant 1.0 ethambutol
embB 4248214 c.1701C>A synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol
embB 4248226 c.1713G>C synonymous_variant 1.0 ethambutol
embB 4248233 c.1720C>T synonymous_variant 1.0 ethambutol
embB 4248241 c.1728C>T synonymous_variant 0.97 ethambutol
embB 4248256 c.1743C>G synonymous_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>C synonymous_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 1.0 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.9 ethambutol
embB 4248372 p.Arg620His missense_variant 1.0 ethambutol
embB 4248382 c.1869C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248448 c.1935C>T synonymous_variant 1.0 ethambutol
embB 4248457 c.1944T>C synonymous_variant 1.0 ethambutol
embB 4248463 c.1950C>G synonymous_variant 1.0 ethambutol
embB 4248469 c.1956C>T synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>C synonymous_variant 1.0 ethambutol
embB 4248488 p.Ala659Ser missense_variant 1.0 ethambutol
embB 4248500 p.Ile663Val missense_variant 1.0 ethambutol
embB 4248504 p.Asp664Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248508 c.1995G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248512 p.Thr667Ser missense_variant 0.93 ethambutol
embB 4248515 p.Val668Ile missense_variant 0.93 ethambutol Not assoc w R - Interim
embB 4248535 c.2022C>A synonymous_variant 0.9 ethambutol
embB 4249387 p.Glu958Asp missense_variant 0.83 ethambutol
embB 4249390 c.2877C>T synonymous_variant 0.86 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.81 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.84 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 0.83 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.86 ethambutol
embB 4249447 c.2934G>C synonymous_variant 0.86 ethambutol
embB 4249450 c.2937C>T synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embB 4249469 p.Leu986Met missense_variant 0.88 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.83 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.82 ethambutol
embB 4249492 c.2979C>G synonymous_variant 0.84 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.9 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.95 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.95 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.95 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.95 ethambutol
embB 4249540 c.3027C>T synonymous_variant 0.95 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 0.9 ethambutol
aftB 4267272 p.Lys522Thr missense_variant 0.9 ethambutol
aftB 4267277 c.1560G>C synonymous_variant 0.82 ethambutol
aftB 4267282 p.Glu519Gln missense_variant 0.82 ethambutol
aftB 4267283 c.1554C>G synonymous_variant 0.82 ethambutol
aftB 4267290 p.Ala516Gln missense_variant 0.82 ethambutol
aftB 4267298 c.1539A>G synonymous_variant 0.82 ethambutol
aftB 4267304 p.Val511Ala missense_variant 0.82 ethambutol
aftB 4267309 c.1528C>T synonymous_variant 0.82 ethambutol
aftB 4267316 c.1521A>G synonymous_variant 0.75 ethambutol
aftB 4268137 c.700C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4268138 c.699A>C synonymous_variant 0.86 ethambutol Not assoc w R - Interim
aftB 4268174 c.663G>C synonymous_variant 0.88 ethambutol
aftB 4268177 c.658_660delTTGinsCT frameshift_variant&missense_variant 0.88 ethambutol Uncertain significance
aftB 4268183 c.654A>G synonymous_variant 0.82 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.88 ethambutol
aftB 4268207 c.630C>G synonymous_variant 0.87 ethambutol
aftB 4268210 c.627C>T synonymous_variant 0.86 ethambutol
aftB 4268213 c.624T>C synonymous_variant 0.86 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.86 ethambutol
aftB 4268228 c.609C>G synonymous_variant 0.85 ethambutol
aftB 4268236 c.601T>C synonymous_variant 0.82 ethambutol
aftB 4268368 p.Cys157Arg missense_variant 0.71 ethambutol
aftB 4268386 c.451T>C synonymous_variant 0.81 ethambutol
aftB 4268389 c.448C>T synonymous_variant 0.81 ethambutol
aftB 4268396 c.441T>C synonymous_variant 0.85 ethambutol
aftB 4268404 c.433T>C synonymous_variant 0.85 ethambutol
aftB 4268406 p.Val144Thr missense_variant 0.89 ethambutol
aftB 4268411 c.426G>A synonymous_variant 0.89 ethambutol
aftB 4268423 c.414C>G synonymous_variant 1.0 ethambutol
aftB 4268450 c.387A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268455 p.Val128Leu missense_variant 1.0 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 1.0 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 0.96 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.96 ethambutol
aftB 4269018 c.-182G>C upstream_gene_variant 0.96 ethambutol
aftB 4269027 c.-191C>A upstream_gene_variant 0.95 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.94 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.94 ethambutol
aftB 4269048 c.-212C>T upstream_gene_variant 0.94 ethambutol
ubiA 4269066 c.768C>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4269123 c.-287T>G upstream_gene_variant 0.75 ethambutol
ubiA 4269131 p.Leu235Met missense_variant 0.83 ethambutol Uncertain significance
aftB 4269143 c.-307T>C upstream_gene_variant 0.83 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.83 ethambutol Not assoc w R - Interim
ubiA 4269152 p.Ala228Ser missense_variant 0.84 ethambutol Uncertain significance
aftB 4269153 c.-317C>G upstream_gene_variant 0.84 ethambutol
aftB 4269156 c.-320C>G upstream_gene_variant 0.86 ethambutol
aftB 4269164 c.-328T>C upstream_gene_variant 0.89 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.91 ethambutol
aftB 4269210 c.-374G>A upstream_gene_variant 0.97 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 0.92 ethambutol
aftB 4269242 c.-406C>T upstream_gene_variant 0.91 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.91 ethambutol
aftB 4269555 c.-719C>G upstream_gene_variant 0.82 ethambutol
ubiA 4269570 c.262_264delAGGinsCA frameshift_variant&missense_variant 0.93 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 0.93 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
aftB 4269609 c.-773G>C upstream_gene_variant 0.93 ethambutol
aftB 4269612 c.-776T>C upstream_gene_variant 0.93 ethambutol
ubiA 4269620 p.Val72Ile missense_variant 0.92 ethambutol
aftB 4269621 c.-785C>G upstream_gene_variant 0.92 ethambutol
ubiA 4269627 c.205_207delGTGinsAC frameshift_variant&missense_variant 0.92 ethambutol
aftB 4269639 c.-803C>G upstream_gene_variant 0.92 ethambutol
ubiA 4269647 p.Ser63Cys missense_variant 0.9 ethambutol