Run ID: ERR2041726
Sample name:
Date: 2024-04-16T02:02:24.873270
Number of reads: 1163251
Percentage reads mapped: 64.97
Median coverage: 56.0
Strain: lineage4.1.2.1
Spoligotype:
Drug-resistance: MDR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.1 | Euro-American | None | 1.0 |
| lineage4.1.2 | Euro-American | None | 1.0 |
| lineage4.1.2.1 | Euro-American (Haarlem) | RD182 | 0.99 |
| lineage4 | Euro-American | None | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | rpoB | p.His445Asp | Assoc w R | |
| isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
| kasA | p.Arg121Lys | Mutation from literature | ||
| ethambutol | embB | p.Gly406Ser | Assoc w R | |
| p.Asp1024Asn | Uncertain significance | Mutation from literature | ||
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.766_768delGCTinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 491548 | c.766_768delGCTinsCC | frameshift_variant&missense_variant | 0.34 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rpoB | 761139 | p.His445Asp | missense_variant | 0.5 | rifampicin | Assoc w R | |
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.44 | streptomycin | Uncertain significance | Mutation from literature |
| katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| kasA | 2518476 | p.Arg121Lys | missense_variant | 0.41 | isoniazid | Mutation from literature | |
| embB | 4247729 | p.Gly406Ser | missense_variant | 0.86 | ethambutol | Assoc w R | |
| embB | 4249583 | p.Asp1024Asn | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 779 | p.Arg260His | missense_variant | 1.0 | isoniazid | Uncertain significance |
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7418 | c.117C>T | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7433 | c.132G>C | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 0.24 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7569 | p.Ala90Ser | missense_variant | 0.25 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7592 | c.291G>T | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7604 | c.303G>A | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8253 | p.Ile318Val | missense_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8318 | c.1017C>G | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8327 | c.1026C>T | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8339 | c.1038A>C | synonymous_variant | 0.23 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 0.23 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8366 | c.1065G>C | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8378 | c.1077C>T | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8426 | c.1125G>A | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8585 | c.1284C>T | synonymous_variant | 0.16 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8600 | c.1299G>A | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8627 | c.1326C>G | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>G | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8649 | p.Arg450Lys | missense_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8708 | c.1407G>C | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8717 | c.1416C>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8720 | c.1419G>A | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 0.27 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8740 | p.Arg480Gln | missense_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8742 | c.1441_1443delGACinsCG | frameshift_variant&missense_variant | 0.28 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8765 | p.Asp488Glu | missense_variant | 0.29 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 0.29 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8769 | p.His490Tyr | missense_variant | 0.29 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8783 | c.1482G>T | synonymous_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8817 | p.Ser506Ala | missense_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8822 | c.1521C>T | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 0.35 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>T | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8882 | c.1581G>A | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 0.37 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 0.36 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 0.36 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9020 | c.1719G>A | synonymous_variant | 0.4 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 0.42 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 0.34 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9063 | p.Ser588Leu | missense_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9074 | c.1773G>T | synonymous_variant | 0.33 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 0.32 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 0.31 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9101 | c.1800A>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 0.29 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9144 | p.Arg615Lys | missense_variant | 0.19 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 0.21 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 0.22 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9224 | c.1923C>T | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9227 | c.1926C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9248 | c.1947G>C | synonymous_variant | 0.2 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.19 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 0.17 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.18 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491307 | c.525C>G | synonymous_variant | 0.31 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491310 | c.528C>G | synonymous_variant | 0.31 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491316 | c.534C>G | synonymous_variant | 0.31 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491320 | p.Ala180Thr | missense_variant | 0.31 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491331 | c.549G>A | synonymous_variant | 0.33 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491340 | c.558C>A | synonymous_variant | 0.41 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 0.43 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>C | synonymous_variant | 0.43 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 0.45 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491367 | c.585G>C | synonymous_variant | 0.45 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491382 | c.600G>A | synonymous_variant | 0.48 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491415 | c.633A>G | synonymous_variant | 0.48 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491418 | c.636A>C | synonymous_variant | 0.46 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491424 | c.642C>T | synonymous_variant | 0.47 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491427 | c.645C>G | synonymous_variant | 0.47 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491430 | c.648T>G | synonymous_variant | 0.47 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491436 | c.654T>C | synonymous_variant | 0.44 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491439 | p.Asp219Glu | missense_variant | 0.44 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491443 | p.Ser221Asp | missense_variant | 0.43 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491454 | c.672C>G | synonymous_variant | 0.41 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 0.43 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491493 | c.711C>G | synonymous_variant | 0.38 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 0.37 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491503 | c.721C>T | synonymous_variant | 0.37 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 0.36 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 0.36 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 0.36 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 0.35 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 0.34 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491553 | c.771G>A | synonymous_variant | 0.33 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491563 | c.781_783delAGCinsTCG | synonymous_variant | 0.33 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491591 | p.Lys270Met | missense_variant | 0.73 | clofazimine | Not assoc w R |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 0.24 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 0.22 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575548 | c.201C>G | synonymous_variant | 0.26 | ethionamide | |
| isoniazid | ||||||
| mshA | 575561 | p.Met72Val | missense_variant | 0.27 | ethionamide | |
| isoniazid | ||||||
| mshA | 575564 | c.217C>T | synonymous_variant | 0.28 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575569 | c.222A>G | synonymous_variant | 0.29 | ethionamide | |
| isoniazid | ||||||
| mshA | 575572 | c.225T>C | synonymous_variant | 0.3 | ethionamide | |
| isoniazid | ||||||
| mshA | 575590 | c.243T>C | synonymous_variant | 0.34 | ethionamide | |
| isoniazid | ||||||
| mshA | 575593 | c.246G>C | synonymous_variant | 0.31 | ethionamide | |
| isoniazid | ||||||
| mshA | 575596 | c.249C>G | synonymous_variant | 0.31 | ethionamide | |
| isoniazid | ||||||
| mshA | 575597 | p.Ile84Val | missense_variant | 0.3 | ethionamide | |
| isoniazid | ||||||
| mshA | 575602 | p.Glu85Asp | missense_variant | 0.29 | ethionamide | |
| isoniazid | ||||||
| mshA | 575609 | p.Ile88Val | missense_variant | 0.28 | ethionamide | |
| isoniazid | ||||||
| mshA | 575620 | c.273G>C | synonymous_variant | 0.25 | ethionamide | |
| isoniazid | ||||||
| mshA | 575626 | c.279C>G | synonymous_variant | 0.24 | ethionamide | |
| isoniazid | ||||||
| mshA | 575627 | c.280_282delGCAinsTG | frameshift_variant&stop_gained | 0.24 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575635 | c.288A>C | synonymous_variant | 0.24 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575641 | c.294A>G | synonymous_variant | 0.24 | ethionamide | |
| isoniazid | ||||||
| mshA | 575649 | p.Val101Ala | missense_variant | 0.24 | ethionamide | |
| isoniazid | ||||||
| mshA | 575652 | p.Arg102His | missense_variant | 0.24 | ethionamide | |
| isoniazid | ||||||
| mshA | 575656 | c.309G>C | synonymous_variant | 0.23 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>C | synonymous_variant | 0.23 | ethionamide | |
| isoniazid | ||||||
| mshA | 575665 | c.318G>C | synonymous_variant | 0.26 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575679 | p.Asn111Ser | missense_variant | 0.71 | ethionamide | Not assoc w R |
| isoniazid | Not assoc w R | |||||
| mshA | 575689 | c.342G>C | synonymous_variant | 0.29 | ethionamide | |
| isoniazid | ||||||
| mshA | 575692 | c.345G>C | synonymous_variant | 0.28 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 0.27 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575701 | c.354G>A | synonymous_variant | 0.28 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 0.28 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 0.29 | ethionamide | |
| isoniazid | ||||||
| mshA | 575714 | p.Tyr123Asn | missense_variant | 0.27 | ethionamide | |
| isoniazid | ||||||
| mshA | 575732 | c.385_387delCTTinsTG | frameshift_variant&missense_variant | 0.22 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.22 | ethionamide | |
| isoniazid | ||||||
| mshA | 575749 | c.402C>G | synonymous_variant | 0.24 | ethionamide | |
| isoniazid | ||||||
| mshA | 575770 | c.423G>C | synonymous_variant | 0.23 | ethionamide | |
| isoniazid | ||||||
| mshA | 575772 | p.Val142Ala | missense_variant | 0.23 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 0.21 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 0.22 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 0.21 | ethionamide | |
| isoniazid | ||||||
| mshA | 575795 | c.448_450delATCinsGG | frameshift_variant&missense_variant | 0.2 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575803 | c.456C>T | synonymous_variant | 0.18 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575812 | c.465C>T | synonymous_variant | 0.17 | ethionamide | |
| isoniazid | ||||||
| Rv0565c | 657269 | p.Ser68Pro | missense_variant | 1.0 | ethionamide | Uncertain significance |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 0.21 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 0.17 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| nusG | 734596 | c.343T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 760115 | c.309C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R |
| rpoB | 760181 | c.375T>G | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| rpoB | 760199 | c.393C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 760253 | c.447T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 760317 | c.511_512delAGinsTC | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 760334 | c.528G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 760337 | c.531C>G | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 760354 | p.Glu183Ala | missense_variant | 0.32 | rifampicin | |
| rpoB | 760357 | p.Thr184Asn | missense_variant | 0.32 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.36 | rifampicin | Uncertain significance |
| rpoB | 760389 | c.583_585delAGCinsTCG | synonymous_variant | 0.32 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 0.35 | rifampicin | Uncertain significance |
| rpoB | 760418 | c.612G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 760448 | c.642C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 760449 | p.Thr215Leu | missense_variant | 0.35 | rifampicin | |
| rpoB | 760460 | c.654G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 760463 | c.657C>G | synonymous_variant | 0.34 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoB | 760527 | p.Gln241Ala | missense_variant | 0.28 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Arg | missense_variant | 0.28 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.29 | rifampicin | Uncertain significance |
| rpoB | 760587 | p.Thr261Ala | missense_variant | 0.2 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.2 | rifampicin | |
| rpoB | 760593 | p.Gly263Asn | missense_variant | 0.2 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoB | 760964 | c.1158C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
| rpoB | 760965 | c.1159_1161delATGinsCC | frameshift_variant&missense_variant | 0.25 | rifampicin | |
| rpoB | 760973 | c.1167G>C | synonymous_variant | 0.33 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 0.53 | rifampicin | |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.53 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.54 | rifampicin | |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 0.52 | rifampicin | |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 0.52 | rifampicin | |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 761195 | c.1389G>T | synonymous_variant | 0.5 | rifampicin | |
| rpoB | 761201 | c.1395G>A | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 761204 | c.1398C>T | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 761222 | c.1416G>C | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761240 | c.1434C>T | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 761258 | c.1452G>A | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>T | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 761318 | c.1512G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoB | 761346 | p.Val514Asn | missense_variant | 0.38 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 0.39 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoB | 761369 | p.Glu521Asp | missense_variant | 0.41 | rifampicin | |
| rpoB | 761374 | p.Val523Glu | missense_variant | 0.41 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 0.36 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 0.34 | rifampicin | |
| rpoB | 761430 | c.1624_1626delATCinsCG | frameshift_variant&missense_variant | 0.34 | rifampicin | |
| rpoB | 761435 | p.Asp543Glu | missense_variant | 0.32 | rifampicin | |
| rpoB | 761437 | p.Ala544Asp | missense_variant | 0.32 | rifampicin | |
| rpoB | 761451 | p.Val549Thr | missense_variant | 0.31 | rifampicin | |
| rpoB | 761457 | p.Pro551Glu | missense_variant | 0.32 | rifampicin | |
| rpoB | 761477 | c.1671C>T | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761482 | p.Ala559Gly | missense_variant | 0.3 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 0.29 | rifampicin | |
| rpoB | 761502 | c.1696_1698delCCCinsTG | frameshift_variant&missense_variant | 0.26 | rifampicin | |
| rpoB | 761508 | c.1702_1704delTCTinsGC | frameshift_variant&missense_variant | 0.25 | rifampicin | |
| rpoB | 761516 | c.1710G>C | synonymous_variant | 0.25 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.28 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 761640 | c.1834C>T | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 0.28 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 0.32 | rifampicin | |
| rpoB | 761682 | c.1876C>T | synonymous_variant | 0.32 | rifampicin | |
| rpoB | 761687 | c.1881C>G | synonymous_variant | 0.32 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761705 | c.1899C>T | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761711 | c.1905C>G | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 0.27 | rifampicin | |
| rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.27 | rifampicin | |
| rpoB | 761732 | c.1926C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761765 | c.1959T>G | synonymous_variant | 0.23 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 0.24 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 0.25 | rifampicin | |
| rpoB | 761790 | p.Arg662Ala | missense_variant | 0.24 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 0.32 | rifampicin | |
| rpoB | 761814 | p.Ala670Asn | missense_variant | 0.33 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761847 | c.2041_2043delTGCinsCG | frameshift_variant&missense_variant | 0.28 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 0.27 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 0.28 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>T | synonymous_variant | 0.28 | rifampicin | |
| rpoB | 761868 | c.2062_2064delGACinsCG | frameshift_variant&missense_variant | 0.28 | rifampicin | |
| rpoB | 761873 | c.2067A>T | synonymous_variant | 0.26 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761892 | p.Ile696Val | missense_variant | 0.31 | rifampicin | |
| rpoB | 761897 | c.2091C>G | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761903 | c.2097T>C | synonymous_variant | 0.31 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 0.3 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 0.33 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 762006 | c.2200_2202delCGCinsAG | frameshift_variant&missense_variant | 0.41 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoB | 762024 | p.Val740Thr | missense_variant | 0.39 | rifampicin | Uncertain significance |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.49 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 0.51 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.49 | rifampicin | |
| rpoB | 762134 | c.2328C>A | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 0.46 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762209 | c.2403C>T | synonymous_variant | 0.44 | rifampicin | |
| rpoB | 762212 | c.2406G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>C | synonymous_variant | 0.48 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 762236 | c.2430G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 762281 | c.2475G>A | synonymous_variant | 0.47 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 0.45 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.41 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.38 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.38 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 0.38 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.37 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.38 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoC | 762407 | c.-963G>C | upstream_gene_variant | 0.41 | rifampicin | |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762452 | c.2646G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 762490 | p.Val895Ala | missense_variant | 0.32 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.26 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.26 | rifampicin | |
| rpoC | 762527 | c.-843G>C | upstream_gene_variant | 0.25 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.17 | rifampicin | |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 762894 | c.3088C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
| rpoC | 762902 | c.-468C>T | upstream_gene_variant | 0.5 | rifampicin | |
| rpoB | 762929 | c.3123G>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 762962 | c.-408C>A | upstream_gene_variant | 0.47 | rifampicin | |
| rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.53 | rifampicin | |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.53 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 763049 | c.-321G>A | upstream_gene_variant | 0.53 | rifampicin | |
| rpoC | 763058 | c.-312C>G | upstream_gene_variant | 0.53 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoB | 763082 | c.3276C>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoB | 763130 | c.3324G>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 763133 | c.-237G>C | upstream_gene_variant | 0.33 | rifampicin | |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 763139 | c.-231C>T | upstream_gene_variant | 0.33 | rifampicin | |
| rpoC | 763142 | c.-228C>G | upstream_gene_variant | 0.32 | rifampicin | |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.33 | rifampicin | |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.31 | rifampicin | |
| rpoC | 763178 | c.-192G>A | upstream_gene_variant | 0.31 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.26 | rifampicin | |
| rpoB | 763203 | p.Ser1133Ala | missense_variant | 0.26 | rifampicin | Uncertain significance |
| rpoB | 763207 | p.Ser1134Lys | missense_variant | 0.25 | rifampicin | Uncertain significance |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.27 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 763262 | c.-108C>A | upstream_gene_variant | 0.2 | rifampicin | |
| rpoC | 763265 | c.-105G>C | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.16 | rifampicin | Uncertain significance |
| rpoC | 763396 | c.27A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 763409 | c.40_42delCTTinsTG | frameshift_variant&missense_variant | 0.29 | rifampicin | |
| rpoC | 763414 | c.45T>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 763430 | c.61A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 763465 | c.96G>A | synonymous_variant | 0.36 | rifampicin | |
| rpoC | 763468 | c.99G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 763492 | c.123G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 763561 | c.192G>A | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoC | 763657 | c.288G>A | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>A | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 763705 | c.336G>C | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 0.31 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 763781 | c.412_414delTCGinsAGC | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 763790 | p.Glu141Thr | missense_variant | 0.23 | rifampicin | |
| rpoC | 763801 | c.432C>T | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763822 | c.453C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763825 | c.456G>A | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 763831 | c.462A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763836 | p.Ala156Val | missense_variant | 0.19 | rifampicin | |
| rpoC | 763840 | c.471G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763844 | p.Arg159Lys | missense_variant | 0.19 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763861 | c.492C>T | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 0.21 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 0.2 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763933 | c.564C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoC | 763936 | c.567C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 0.21 | rifampicin | Uncertain significance |
| rpoC | 763978 | c.609C>T | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763987 | c.618C>T | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764030 | p.Asp221Asn | missense_variant | 0.16 | rifampicin | Uncertain significance |
| rpoC | 764059 | c.690G>T | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764080 | c.711C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764085 | p.Asn239Thr | missense_variant | 0.19 | rifampicin | Uncertain significance |
| rpoC | 764095 | c.726C>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| rpoC | 764134 | c.765C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| rpoC | 764140 | c.771C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| rpoC | 764143 | c.774G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 764161 | c.792G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764169 | p.Asn267Thr | missense_variant | 0.2 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoC | 764207 | p.Val280Thr | missense_variant | 0.21 | rifampicin | Uncertain significance |
| rpoC | 764213 | p.Arg282Lys | missense_variant | 0.22 | rifampicin | Uncertain significance |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoC | 764293 | c.924G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoC | 764317 | c.948C>G | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 764320 | c.951C>G | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.31 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 764410 | c.1041G>C | synonymous_variant | 0.32 | rifampicin | |
| rpoC | 764429 | c.1060C>T | synonymous_variant | 0.32 | rifampicin | |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066A>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764455 | c.1086G>T | synonymous_variant | 0.29 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 764515 | c.1146C>T | synonymous_variant | 0.33 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 764551 | c.1182G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>G | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 764863 | c.1494G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>C | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 0.27 | rifampicin | Uncertain significance |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
| rpoC | 764962 | c.1593G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoC | 765031 | c.1662G>A | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>T | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>T | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
| rpoC | 765150 | p.Gly594Glu | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765277 | c.1908G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
| rpoC | 765281 | p.Thr638Asp | missense_variant | 0.17 | rifampicin | Uncertain significance |
| rpoC | 765300 | p.Val644Ala | missense_variant | 0.19 | rifampicin | Uncertain significance |
| rpoC | 765305 | c.1936_1938delATCinsGG | frameshift_variant&missense_variant | 0.19 | rifampicin | |
| rpoC | 765311 | p.Ala648Thr | missense_variant | 0.18 | rifampicin | Uncertain significance |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Asp | missense_variant | 0.18 | rifampicin | |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 0.18 | rifampicin | Uncertain significance |
| rpoC | 765339 | p.Gln657Arg | missense_variant | 0.18 | rifampicin | Uncertain significance |
| rpoC | 765343 | c.1974G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 765346 | c.1977C>T | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
| rpoC | 765359 | p.Ala664Thr | missense_variant | 0.19 | rifampicin | |
| rpoC | 765403 | c.2034G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765404 | p.Leu679Val | missense_variant | 0.22 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 765445 | c.2076G>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoC | 765453 | p.Ala695Val | missense_variant | 0.35 | rifampicin | Uncertain significance |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 765508 | c.2139C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 765547 | c.2178C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 765553 | c.2184C>G | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 765607 | c.2238C>G | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 0.44 | rifampicin | Uncertain significance |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 765662 | c.2293_2295delTTGinsCC | frameshift_variant&missense_variant | 0.41 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
| rpoC | 765718 | p.Asp783Glu | missense_variant | 0.43 | rifampicin | Uncertain significance |
| rpoC | 765724 | c.2355C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 765742 | p.Glu791Asp | missense_variant | 0.45 | rifampicin | Uncertain significance |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 0.46 | rifampicin | Uncertain significance |
| rpoC | 765790 | c.2421C>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.48 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 0.49 | rifampicin | Uncertain significance |
| rpoC | 765884 | c.2515_2516delTCinsAG | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 765946 | c.2577C>T | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
| rpoC | 765991 | c.2622C>G | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| rpoC | 766009 | c.2640G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 766480 | c.3111C>G | synonymous_variant | 0.47 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.43 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 766517 | p.Thr1050Ala | missense_variant | 0.45 | rifampicin | |
| rpoC | 766522 | c.3153C>A | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.43 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.42 | rifampicin | |
| rpoC | 766546 | p.Glu1059Asp | missense_variant | 0.41 | rifampicin | |
| rpoC | 766547 | p.Arg1060Lys | missense_variant | 0.4 | rifampicin | |
| rpoC | 766564 | c.3195C>G | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 766570 | c.3201T>G | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 766573 | c.3204T>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 766582 | c.3213C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 766607 | c.3238_3240delATCinsTG | frameshift_variant&missense_variant | 0.43 | rifampicin | |
| rpoC | 766610 | p.Ser1081Pro | missense_variant | 0.43 | rifampicin | |
| rpoC | 766618 | c.3249G>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 766642 | c.3273C>T | synonymous_variant | 0.44 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 766661 | p.Val1098Leu | missense_variant | 0.41 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 0.39 | rifampicin | |
| rpoC | 766667 | p.Ser1100Ala | missense_variant | 0.39 | rifampicin | Uncertain significance |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 766675 | c.3306C>T | synonymous_variant | 0.41 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 766693 | c.3324C>A | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 766702 | c.3333G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 766708 | c.3339A>G | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 0.33 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 766771 | c.3402G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 0.31 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 0.31 | rifampicin | |
| rpoC | 766787 | p.Glu1140Gln | missense_variant | 0.31 | rifampicin | Uncertain significance |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | c.3514_3516delTCGinsGC | frameshift_variant&missense_variant | 0.37 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 0.37 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 0.37 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 0.38 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 0.4 | rifampicin | |
| rpoC | 766911 | p.Ile1181Thr | missense_variant | 0.41 | rifampicin | |
| rpoC | 766915 | p.Asp1182Glu | missense_variant | 0.42 | rifampicin | |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 0.42 | rifampicin | |
| rpoC | 766931 | c.3562_3564delGCAinsAC | frameshift_variant&missense_variant | 0.41 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 766978 | c.3609C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 766996 | c.3627C>G | synonymous_variant | 0.51 | rifampicin | |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
| rpoC | 767020 | c.3651C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 767023 | c.3654C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 767032 | c.3663G>C | synonymous_variant | 0.52 | rifampicin | |
| rpoC | 767059 | c.3690T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | c.3736_3738delAACinsCG | frameshift_variant&missense_variant | 0.52 | rifampicin | |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>G | synonymous_variant | 0.51 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 0.45 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
| bedaquiline | Not assoc w R - Interim | |||||
| rpsL | 781276 | c.-284A>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
| rpsL | 781628 | c.69T>C | synonymous_variant | 0.22 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 0.23 | streptomycin | |
| rpsL | 781649 | c.90T>G | synonymous_variant | 0.28 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.26 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 0.26 | streptomycin | |
| rpsL | 781664 | c.105C>T | synonymous_variant | 0.28 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.38 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 0.41 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>G | synonymous_variant | 0.42 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 0.42 | streptomycin | |
| rpsL | 781726 | p.Lys56Arg | missense_variant | 0.42 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 0.41 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 0.41 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 0.39 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 0.41 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 0.41 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.41 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.42 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 0.44 | streptomycin | |
| rpsL | 781784 | c.225G>A | synonymous_variant | 0.45 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.44 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.43 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 0.43 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 0.35 | streptomycin | Not assoc w R - Interim |
| rpsL | 781868 | c.309T>C | synonymous_variant | 0.33 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 0.32 | streptomycin | |
| rpsL | 781877 | c.318T>G | synonymous_variant | 0.32 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 0.27 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 0.27 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 0.25 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 0.23 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.18 | streptomycin | Uncertain significance |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.2 | linezolid | |
| rplC | 800558 | c.-251G>A | upstream_gene_variant | 0.18 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800570 | c.-239C>G | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800574 | c.-235_-234delGTinsAC | upstream_gene_variant | 0.18 | linezolid | |
| rplC | 800588 | c.-221C>G | upstream_gene_variant | 0.18 | linezolid | |
| rplC | 800589 | c.-220_-219delAGinsTC | upstream_gene_variant | 0.18 | linezolid | |
| rplC | 800600 | c.-209G>C | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.2 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.21 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 0.23 | linezolid | |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.23 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.24 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 0.27 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.28 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.25 | linezolid | |
| rplC | 800744 | c.-65G>C | upstream_gene_variant | 0.21 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.17 | linezolid | Not assoc w R - Interim |
| rplC | 800985 | c.177A>T | synonymous_variant | 0.18 | linezolid | |
| rplC | 801009 | c.201A>C | synonymous_variant | 0.17 | linezolid | |
| rplC | 801019 | p.Thr71Ala | missense_variant | 0.18 | linezolid | |
| rplC | 801066 | c.258G>T | synonymous_variant | 0.16 | linezolid | |
| rplC | 801147 | c.339T>C | synonymous_variant | 0.17 | linezolid | |
| rplC | 801156 | c.348T>C | synonymous_variant | 0.2 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 0.21 | linezolid | |
| rplC | 801206 | p.Arg133Pro | missense_variant | 0.18 | linezolid | |
| rplC | 801216 | c.408C>T | synonymous_variant | 0.19 | linezolid | |
| rplC | 801220 | c.412_414delAGTinsGC | frameshift_variant&missense_variant | 0.19 | linezolid | |
| rplC | 801231 | c.423C>T | synonymous_variant | 0.17 | linezolid | |
| fbiC | 1303788 | c.858T>C | synonymous_variant | 0.18 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305267 | c.2337C>G | synonymous_variant | 0.18 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305277 | p.His783Asn | missense_variant | 0.17 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305311 | p.Arg794Gln | missense_variant | 0.17 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305331 | p.Glu801Lys | missense_variant | 0.16 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.26 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471926 | n.81C>T | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.28 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471985 | n.140T>C | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472042 | n.197T>C | non_coding_transcript_exon_variant | 0.5 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.51 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.5 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.51 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.51 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472292 | n.447A>G | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472298 | n.453G>C | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472302 | n.457_458insT | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472310 | n.465_466insG | non_coding_transcript_exon_variant | 0.45 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472314 | n.469A>G | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.44 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 0.47 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 0.46 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 0.45 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 0.46 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472456 | n.611T>C | non_coding_transcript_exon_variant | 0.46 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472683 | n.838_839insTA | non_coding_transcript_exon_variant | 0.5 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472846 | n.1001C>A | non_coding_transcript_exon_variant | 0.48 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 0.49 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 0.48 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.48 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 0.5 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472861 | n.1016G>T | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473111 | n.1266A>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.41 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473792 | n.135C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1473793 | n.136G>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1473802 | n.145C>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473812 | n.155G>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473814 | n.157A>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473816 | n.159C>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473828 | n.171_175delGGTGCinsCCGGTG | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
| linezolid | ||||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473922 | n.265A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1473923 | n.266C>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1473935 | n.278C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474002 | n.345G>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
| linezolid | ||||||
| rrl | 1474016 | n.359C>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
| linezolid | ||||||
| rrl | 1474026 | n.369C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
| linezolid | ||||||
| rrl | 1474083 | n.426C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474094 | n.437C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474105 | n.448delTinsCG | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474108 | n.451C>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474110 | n.453A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474202 | n.545T>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474263 | n.606G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474287 | n.630_631insTC | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
| linezolid | ||||||
| rrl | 1474293 | n.637_646delCCTCTCCGGA | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
| linezolid | ||||||
| rrl | 1474306 | n.649A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
| linezolid | ||||||
| rrl | 1474350 | n.693G>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
| linezolid | ||||||
| rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474374 | n.717T>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474421 | n.764G>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474427 | n.770A>C | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1474430 | n.773delCinsTTG | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1474432 | n.775C>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
| linezolid | ||||||
| rrl | 1474438 | n.781A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474439 | n.782A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
| linezolid | ||||||
| rrl | 1474452 | n.795C>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
| linezolid | ||||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474710 | n.1053T>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474711 | n.1054G>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474713 | n.1056T>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
| linezolid | ||||||
| rrl | 1474715 | n.1058_1059insC | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
| linezolid | ||||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474952 | n.1296delC | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
| linezolid | ||||||
| rrl | 1474957 | n.1301_1308delACCTTGTG | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
| linezolid | ||||||
| rrl | 1474969 | n.1312_1315delGGTGinsAGGAT | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
| linezolid | ||||||
| rrl | 1474990 | n.1333C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474991 | n.1334T>G | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474995 | n.1338T>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474997 | n.1340A>G | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474999 | n.1342C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475008 | n.1351C>A | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475010 | n.1353G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
| linezolid | ||||||
| rrl | 1475015 | n.1358_1360delCCGinsTCTA | non_coding_transcript_exon_variant | 0.49 | capreomycin | |
| linezolid | ||||||
| rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475037 | n.1380T>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475062 | n.1405A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475120 | n.1463G>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475239 | n.1582_1583delACinsTGGCAG | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
| linezolid | ||||||
| rrl | 1475241 | n.1584C>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
| linezolid | ||||||
| rrl | 1475247 | n.1589_1590insT | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
| linezolid | ||||||
| rrl | 1475250 | n.1594_1598delACTCC | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
| linezolid | ||||||
| rrl | 1475272 | n.1615G>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
| linezolid | ||||||
| rrl | 1475273 | n.1616T>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1475278 | n.1621delGinsCC | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
| linezolid | ||||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475297 | n.1640C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475363 | n.1706C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475375 | n.1718G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475380 | n.1723C>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475381 | n.1724G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
| linezolid | ||||||
| rrl | 1475382 | n.1725A>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
| linezolid | ||||||
| rrl | 1475395 | n.1738T>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1475396 | n.1739C>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1475397 | n.1740G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1475403 | n.1746T>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
| linezolid | ||||||
| rrl | 1475404 | n.1747A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1475407 | n.1750C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1475409 | n.1752T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475428 | n.1771G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475430 | n.1773T>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
| linezolid | ||||||
| rrl | 1475433 | n.1776A>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475458 | n.1801C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
| linezolid | ||||||
| rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475482 | n.1825A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475603 | n.1946G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475614 | n.1957A>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
| linezolid | ||||||
| rrl | 1475615 | n.1958C>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
| linezolid | ||||||
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
| linezolid | ||||||
| rrl | 1475619 | n.1962C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
| linezolid | ||||||
| rrl | 1475621 | n.1964T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475626 | n.1969delTinsCC | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
| linezolid | ||||||
| rrl | 1475629 | n.1972G>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
| linezolid | ||||||
| rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475762 | n.2105delGinsCTT | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
| linezolid | ||||||
| rrl | 1475764 | n.2107A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476103 | n.2446C>A | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476108 | n.2451T>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476246 | n.2589G>A | non_coding_transcript_exon_variant | 0.63 | capreomycin | |
| linezolid | ||||||
| rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
| linezolid | ||||||
| rrl | 1476262 | n.2605G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
| linezolid | ||||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476665 | n.3008T>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036delGinsCA | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
| linezolid | ||||||
| rrl | 1476731 | n.3074G>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
| linezolid | ||||||
| inhA | 1674486 | c.285T>C | synonymous_variant | 0.21 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674507 | c.306G>C | synonymous_variant | 0.2 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674514 | p.Ile105Val | missense_variant | 0.21 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674534 | c.333G>C | synonymous_variant | 0.2 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674537 | c.336C>G | synonymous_variant | 0.19 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 0.18 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674579 | c.378G>C | synonymous_variant | 0.18 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833540 | c.-2_-1delATinsC | upstream_gene_variant | 0.22 | pyrazinamide | |
| rpsA | 1833547 | c.6G>A | synonymous_variant | 0.31 | pyrazinamide | |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.33 | pyrazinamide | |
| rpsA | 1833604 | c.63C>T | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 0.36 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1833658 | c.117C>G | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1833730 | c.189C>T | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.4 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833754 | c.213G>A | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1833770 | p.Asn77His | missense_variant | 0.47 | pyrazinamide | |
| rpsA | 1833778 | c.237C>G | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1833781 | c.240T>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833796 | c.255G>A | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1833814 | c.273C>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1833862 | c.321G>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1833892 | c.351G>A | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.42 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.41 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.42 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834018 | c.477C>T | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834039 | c.498C>T | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834040 | p.Lys167Arg | missense_variant | 0.39 | pyrazinamide | |
| rpsA | 1834094 | c.553C>T | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.37 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 0.37 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 0.38 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.39 | pyrazinamide | Uncertain significance |
| rpsA | 1834172 | p.Ile211Val | missense_variant | 0.39 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834183 | c.642T>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 0.38 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 0.36 | pyrazinamide | |
| rpsA | 1834231 | c.690T>G | synonymous_variant | 0.37 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 0.37 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 0.33 | pyrazinamide | |
| rpsA | 1834333 | c.792C>T | synonymous_variant | 0.36 | pyrazinamide | |
| rpsA | 1834336 | c.795C>G | synonymous_variant | 0.35 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>C | synonymous_variant | 0.4 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.48 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834525 | c.984G>A | synonymous_variant | 0.48 | pyrazinamide | |
| rpsA | 1834527 | p.Arg329Gln | missense_variant | 0.47 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834558 | c.1017C>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834564 | c.1023C>T | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834579 | c.1038C>G | synonymous_variant | 0.47 | pyrazinamide | |
| rpsA | 1834603 | p.Glu354Asp | missense_variant | 0.48 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.45 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834627 | c.1086C>T | synonymous_variant | 0.44 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.46 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 0.48 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.49 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.43 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.39 | pyrazinamide | |
| rpsA | 1834751 | c.1210_1212delCTTinsAC | frameshift_variant&missense_variant | 0.34 | pyrazinamide | Uncertain significance |
| rpsA | 1834759 | c.1218A>T | synonymous_variant | 0.32 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.33 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.31 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.3 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.29 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.28 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.27 | pyrazinamide | |
| tsnR | 1853370 | c.-236_-234delGCAinsAC | upstream_gene_variant | 0.27 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.26 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 0.24 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.25 | linezolid | |
| tsnR | 1853401 | c.-205A>G | upstream_gene_variant | 0.26 | linezolid | |
| tsnR | 1853403 | c.-203A>G | upstream_gene_variant | 0.26 | linezolid | |
| tsnR | 1853417 | c.-189G>C | upstream_gene_variant | 0.2 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.2 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.17 | linezolid | |
| tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
| ndh | 2102305 | c.738T>C | synonymous_variant | 0.19 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102323 | c.720C>T | synonymous_variant | 0.17 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102377 | c.666A>G | synonymous_variant | 0.19 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102401 | c.642T>C | synonymous_variant | 0.21 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102407 | c.636T>C | synonymous_variant | 0.21 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102416 | c.627G>A | synonymous_variant | 0.26 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102436 | p.His203Asn | missense_variant | 0.25 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102437 | c.606G>C | synonymous_variant | 0.25 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102443 | c.600A>G | synonymous_variant | 0.26 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102452 | c.589_591delTTGinsCC | frameshift_variant&missense_variant | 0.21 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102460 | p.His195Tyr | missense_variant | 0.21 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102461 | c.580_582delGAGinsAC | frameshift_variant&missense_variant | 0.21 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102470 | c.573G>A | synonymous_variant | 0.21 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102482 | c.561A>G | synonymous_variant | 0.19 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
| bedaquiline | Not assoc w R - Interim | |||||
| kasA | 2518076 | c.-39C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518279 | c.165T>C | synonymous_variant | 0.18 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 0.18 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 0.18 | isoniazid | |
| kasA | 2518290 | p.Lys59Arg | missense_variant | 0.25 | isoniazid | |
| kasA | 2518300 | c.186T>G | synonymous_variant | 0.26 | isoniazid | |
| kasA | 2518303 | c.189C>T | synonymous_variant | 0.26 | isoniazid | |
| kasA | 2518309 | c.195G>A | synonymous_variant | 0.26 | isoniazid | |
| kasA | 2518312 | c.198T>C | synonymous_variant | 0.27 | isoniazid | |
| kasA | 2518322 | p.Ser70Asp | missense_variant | 0.31 | isoniazid | |
| kasA | 2518336 | c.222A>G | synonymous_variant | 0.34 | isoniazid | |
| kasA | 2518337 | c.223_225delCTCinsTG | frameshift_variant&missense_variant | 0.34 | isoniazid | |
| kasA | 2518343 | p.Met77Leu | missense_variant | 0.34 | isoniazid | |
| kasA | 2518348 | c.234A>G | synonymous_variant | 0.36 | isoniazid | |
| kasA | 2518374 | p.Gly87Ala | missense_variant | 0.38 | isoniazid | |
| kasA | 2518379 | c.265T>C | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518384 | c.270G>C | synonymous_variant | 0.37 | isoniazid | |
| kasA | 2518385 | p.Gly91Ser | missense_variant | 0.35 | isoniazid | |
| kasA | 2518390 | c.276A>C | synonymous_variant | 0.35 | isoniazid | |
| kasA | 2518392 | p.Gln93Arg | missense_variant | 0.35 | isoniazid | |
| kasA | 2518396 | c.282A>C | synonymous_variant | 0.31 | isoniazid | |
| kasA | 2518403 | p.Ser97Asn | missense_variant | 0.37 | isoniazid | |
| kasA | 2518413 | p.Ser100Thr | missense_variant | 0.38 | isoniazid | |
| kasA | 2518423 | c.309C>G | synonymous_variant | 0.39 | isoniazid | |
| kasA | 2518426 | c.312T>C | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518429 | c.315A>G | synonymous_variant | 0.38 | isoniazid | |
| kasA | 2518439 | p.Ala109Thr | missense_variant | 0.39 | isoniazid | |
| kasA | 2518444 | c.330T>G | synonymous_variant | 0.4 | isoniazid | |
| kasA | 2518447 | c.333T>G | synonymous_variant | 0.39 | isoniazid | |
| kasA | 2518448 | p.Val112Ile | missense_variant | 0.39 | isoniazid | |
| kasA | 2518459 | c.345T>C | synonymous_variant | 0.36 | isoniazid | |
| kasA | 2518462 | c.348A>G | synonymous_variant | 0.36 | isoniazid | |
| kasA | 2518465 | c.351T>C | synonymous_variant | 0.36 | isoniazid | |
| kasA | 2518468 | c.354A>C | synonymous_variant | 0.36 | isoniazid | |
| kasA | 2518470 | p.Ala119Gly | missense_variant | 0.36 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 0.4 | isoniazid | |
| kasA | 2518488 | p.Ser125Thr | missense_variant | 0.43 | isoniazid | |
| kasA | 2518492 | c.378C>T | synonymous_variant | 0.43 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 0.47 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 0.44 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 0.44 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 0.43 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 0.43 | isoniazid | |
| kasA | 2518570 | c.456G>A | synonymous_variant | 0.45 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 0.46 | isoniazid | |
| kasA | 2518579 | c.465T>G | synonymous_variant | 0.48 | isoniazid | |
| kasA | 2518588 | c.474T>C | synonymous_variant | 0.47 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 0.48 | isoniazid | |
| kasA | 2518606 | c.492G>C | synonymous_variant | 0.47 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 0.48 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 0.5 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 0.52 | isoniazid | |
| kasA | 2518657 | c.543G>C | synonymous_variant | 0.54 | isoniazid | |
| kasA | 2518663 | c.549T>C | synonymous_variant | 0.55 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 0.57 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 0.53 | isoniazid | |
| kasA | 2518688 | p.Val192Phe | missense_variant | 0.53 | isoniazid | |
| kasA | 2518705 | c.591T>G | synonymous_variant | 0.48 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 0.4 | isoniazid | |
| kasA | 2518715 | p.Pro201Gly | missense_variant | 0.38 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 0.4 | isoniazid | |
| kasA | 2518739 | p.Ala209Thr | missense_variant | 0.39 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 0.35 | isoniazid | |
| kasA | 2518756 | c.642G>C | synonymous_variant | 0.3 | isoniazid | |
| kasA | 2518759 | c.645C>G | synonymous_variant | 0.31 | isoniazid | |
| kasA | 2518780 | p.Glu222Asp | missense_variant | 0.27 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 0.27 | isoniazid | |
| kasA | 2518787 | c.673_675delCGGinsGC | frameshift_variant&missense_variant | 0.28 | isoniazid | |
| kasA | 2518816 | c.702C>G | synonymous_variant | 0.24 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 0.22 | isoniazid | |
| kasA | 2518843 | c.729T>C | synonymous_variant | 0.21 | isoniazid | |
| kasA | 2518847 | p.Leu245Met | missense_variant | 0.21 | isoniazid | |
| kasA | 2518853 | p.Leu247Ile | missense_variant | 0.22 | isoniazid | |
| Rv2477c | 2782615 | c.1428G>A | synonymous_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782621 | c.1422T>C | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782668 | p.Gln459Glu | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782675 | c.1368G>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782680 | c.1363T>C | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782684 | c.1359T>G | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782690 | c.1353C>G | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782695 | c.1348A>C | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782702 | c.1341G>A | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782705 | c.1338G>C | synonymous_variant | 0.21 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782862 | p.Ala394Val | missense_variant | 0.85 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Uncertain significance | |||||
| amikacin | ||||||
| Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.26 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782924 | c.1119G>C | synonymous_variant | 0.22 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782928 | p.Thr372Glu | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.23 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782963 | c.1080G>A | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782972 | c.1071G>T | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782987 | c.1056C>G | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783014 | p.Ser343Thr | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783037 | c.1006C>T | synonymous_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783038 | p.Ala335Met | missense_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783041 | c.1002C>G | synonymous_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783044 | c.999G>C | synonymous_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783053 | c.990C>G | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>G | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783084 | p.Val320Gln | missense_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783087 | p.Asn319Ser | missense_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.17 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783105 | p.Val313Thr | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783134 | c.909G>A | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.22 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783158 | p.Ala295Val | missense_variant | 0.22 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Uncertain significance | |||||
| amikacin | ||||||
| Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.25 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783192 | p.Ser284Asn | missense_variant | 0.28 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.29 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783206 | c.837G>C | synonymous_variant | 0.28 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783215 | c.828G>C | synonymous_variant | 0.25 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783218 | c.825C>G | synonymous_variant | 0.26 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.24 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783230 | c.813T>C | synonymous_variant | 0.22 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.22 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783242 | p.Thr267Gln | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783247 | c.796T>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | p.Gln255Ala | missense_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783289 | p.Leu252Ile | missense_variant | 0.22 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783290 | c.753G>C | synonymous_variant | 0.21 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.23 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.25 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.33 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783344 | c.699C>G | synonymous_variant | 0.38 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.36 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.35 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 0.34 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783365 | c.678C>T | synonymous_variant | 0.34 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783377 | c.666C>G | synonymous_variant | 0.36 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783386 | c.657G>C | synonymous_variant | 0.36 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>C | synonymous_variant | 0.38 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783407 | c.636C>G | synonymous_variant | 0.37 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.36 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | c.618C>G | synonymous_variant | 0.37 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.35 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783444 | p.Gln200Ser | missense_variant | 0.39 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783449 | c.594C>G | synonymous_variant | 0.38 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 0.32 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.33 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.33 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.37 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 0.33 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.34 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783506 | c.537C>T | synonymous_variant | 0.36 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.38 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783523 | c.520C>T | synonymous_variant | 0.38 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.41 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.42 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.42 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>G | synonymous_variant | 0.43 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.44 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783563 | c.480A>C | synonymous_variant | 0.42 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.44 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.45 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.45 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.43 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783626 | c.415_417delGCGinsTT | frameshift_variant&missense_variant | 0.44 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783634 | p.Leu137Ile | missense_variant | 0.44 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783646 | p.Asp133Asn | missense_variant | 0.45 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.45 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.43 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.45 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.43 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783692 | c.351G>A | synonymous_variant | 0.41 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.39 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.39 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783728 | c.315G>A | synonymous_variant | 0.37 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783737 | c.306C>G | synonymous_variant | 0.37 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783743 | c.300C>G | synonymous_variant | 0.36 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.34 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.35 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783764 | c.277_279delATGinsCC | frameshift_variant&missense_variant | 0.29 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783773 | c.270A>G | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.3 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.31 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783788 | c.255T>C | synonymous_variant | 0.32 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783791 | c.252C>G | synonymous_variant | 0.32 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.31 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.24 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783824 | c.219G>C | synonymous_variant | 0.24 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783837 | p.Thr69Ser | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783842 | c.201C>A | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783845 | c.196_198delACCinsCG | frameshift_variant&synonymous_variant | 0.2 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783857 | c.186C>G | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783866 | c.177C>T | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783872 | c.171G>C | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783875 | p.Lys56Thr | missense_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.22 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.25 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783926 | c.117C>G | synonymous_variant | 0.21 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783935 | c.108C>G | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Leu | missense_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783986 | c.57G>C | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| thyX | 3067244 | c.702C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074495 | c.-24C>T | upstream_gene_variant | 1.0 | para-aminosalicylic_acid | |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
| lpqB | 3625060 | c.-150G>C | upstream_gene_variant | 0.21 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Not assoc w R | |||||
| lpqB | 3625069 | c.-159T>G | upstream_gene_variant | 0.21 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625075 | c.-165G>C | upstream_gene_variant | 0.24 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625093 | p.Glu507Lys | missense_variant | 0.24 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625111 | c.-201G>C | upstream_gene_variant | 0.24 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.25 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.27 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 0.31 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625135 | c.1479A>G | synonymous_variant | 0.31 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 0.32 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625150 | c.-240C>T | upstream_gene_variant | 0.37 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625162 | c.-252T>G | upstream_gene_variant | 0.36 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625177 | c.-267C>G | upstream_gene_variant | 0.39 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 0.4 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625198 | c.-288C>G | upstream_gene_variant | 0.39 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625204 | c.1408_1410delTCGinsGC | frameshift_variant&missense_variant | 0.38 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.4 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625240 | c.-330T>G | upstream_gene_variant | 0.39 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 0.31 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625351 | c.1263T>C | synonymous_variant | 0.31 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.29 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.29 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.3 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625585 | c.-675G>C | upstream_gene_variant | 0.31 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.32 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625599 | p.Met339Leu | missense_variant | 0.31 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.31 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625623 | p.Thr331Ser | missense_variant | 0.3 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625627 | p.Asp329Glu | missense_variant | 0.3 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 0.3 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625636 | p.Ala326Glu | missense_variant | 0.27 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625645 | c.969C>T | synonymous_variant | 0.26 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625648 | c.964_966delTATinsCC | frameshift_variant&missense_variant | 0.26 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 0.25 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.26 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.23 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.24 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 0.25 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 0.26 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.27 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.23 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 0.22 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 0.18 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625819 | c.795G>A | synonymous_variant | 0.18 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626684 | c.-71G>T | upstream_gene_variant | 0.17 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.2 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626717 | c.-104C>T | upstream_gene_variant | 0.2 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 0.2 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.21 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626729 | c.619_621delAAGinsCA | frameshift_variant&missense_variant | 0.2 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.2 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626735 | c.-122C>A | upstream_gene_variant | 0.2 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626738 | c.-125G>A | upstream_gene_variant | 0.24 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 0.26 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 0.28 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626776 | c.-163A>C | upstream_gene_variant | 0.27 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.28 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 0.29 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 0.32 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626804 | c.-191A>C | upstream_gene_variant | 0.36 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626816 | c.-203G>C | upstream_gene_variant | 0.4 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626822 | p.Asp176Glu | missense_variant | 0.39 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626825 | c.-212T>G | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626843 | c.-230G>C | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 0.42 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 0.43 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 0.41 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.41 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>G | upstream_gene_variant | 0.44 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.43 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 0.43 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626907 | p.Asn148Gly | missense_variant | 0.46 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626912 | p.Thr146Ser | missense_variant | 0.43 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626924 | c.-311G>A | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.43 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 0.44 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626942 | c.406_408delGTAinsAC | frameshift_variant&missense_variant | 0.41 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.44 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 0.45 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.45 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626999 | c.-386G>C | upstream_gene_variant | 0.52 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.53 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 0.52 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627053 | c.297C>T | synonymous_variant | 0.52 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627056 | c.294C>T | synonymous_variant | 0.52 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627068 | c.282T>G | synonymous_variant | 0.52 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 0.54 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 0.52 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.52 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 0.45 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 0.46 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627122 | c.-509T>G | upstream_gene_variant | 0.44 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.46 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627131 | p.Ala73Lys | missense_variant | 0.45 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.45 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.42 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 0.41 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627188 | c.160_162delTTAinsCG | frameshift_variant&missense_variant | 0.4 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627194 | c.-581G>A | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 0.39 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627213 | p.Arg46His | missense_variant | 0.4 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627224 | c.-611G>C | upstream_gene_variant | 0.4 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627227 | c.-614T>G | upstream_gene_variant | 0.38 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.37 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.35 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627247 | p.Ile35Val | missense_variant | 0.36 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.32 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.32 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>C | upstream_gene_variant | 0.32 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.22 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 0.23 | bedaquiline | |
| rifampicin | ||||||
| fbiB | 3640743 | c.-792T>C | upstream_gene_variant | 0.17 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.18 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877569 | c.937_939delCCGinsGC | frameshift_variant&missense_variant | 0.19 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877593 | c.915C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877596 | c.912G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877611 | c.895_897delATCinsGG | frameshift_variant&missense_variant | 0.26 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 0.26 | rifampicin | |
| rpoA | 3877638 | c.870T>G | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 0.28 | rifampicin | |
| rpoA | 3877677 | c.831G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877689 | c.819C>G | synonymous_variant | 0.3 | rifampicin | |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877695 | c.813C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877785 | c.723C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877788 | c.720G>A | synonymous_variant | 0.38 | rifampicin | |
| rpoA | 3877815 | c.693C>A | synonymous_variant | 0.38 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.37 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.37 | rifampicin | |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877881 | c.627G>C | synonymous_variant | 0.36 | rifampicin | |
| rpoA | 3877893 | c.615C>G | synonymous_variant | 0.35 | rifampicin | |
| rpoA | 3877905 | c.603A>C | synonymous_variant | 0.33 | rifampicin | |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877929 | c.577_579delATCinsGG | frameshift_variant&missense_variant | 0.3 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 0.29 | rifampicin | Uncertain significance |
| rpoA | 3877974 | c.534G>C | synonymous_variant | 0.3 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878073 | c.435C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878082 | c.426T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878093 | p.Val139Ile | missense_variant | 0.23 | rifampicin | |
| rpoA | 3878094 | c.412_414delCTCinsTG | frameshift_variant&synonymous_variant | 0.23 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 0.25 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.26 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoA | 3878124 | c.384G>C | synonymous_variant | 0.27 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 0.26 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 0.28 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.29 | rifampicin | Uncertain significance |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 0.33 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878166 | c.342C>G | synonymous_variant | 0.33 | rifampicin | |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878196 | p.Glu104Ala | missense_variant | 0.36 | rifampicin | Uncertain significance |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878244 | p.Glu88Asp | missense_variant | 0.37 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoA | 3878253 | c.255G>C | synonymous_variant | 0.38 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 0.35 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878276 | c.232C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.36 | rifampicin | Uncertain significance |
| rpoA | 3878295 | c.213A>G | synonymous_variant | 0.35 | rifampicin | |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 0.35 | rifampicin | |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 0.32 | rifampicin | |
| rpoA | 3878316 | c.192C>G | synonymous_variant | 0.32 | rifampicin | |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 0.28 | rifampicin | |
| rpoA | 3878358 | c.150C>G | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 0.3 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3878391 | c.117T>C | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3878394 | c.114G>T | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 0.29 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 0.33 | rifampicin | |
| rpoA | 3878454 | c.54A>C | synonymous_variant | 0.28 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.39 | rifampicin | |
| rpoA | 3878775 | c.-268A>G | upstream_gene_variant | 0.39 | rifampicin | Uncertain significance |
| rpoA | 3878782 | c.-275G>C | upstream_gene_variant | 0.39 | rifampicin | |
| rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 0.39 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.39 | rifampicin | Uncertain significance |
| rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 0.41 | rifampicin | |
| rpoA | 3878808 | c.-301G>T | upstream_gene_variant | 0.42 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.44 | rifampicin | |
| rpoA | 3878830 | c.-325_-323delCTGinsAC | upstream_gene_variant | 0.41 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.41 | rifampicin | |
| rpoA | 3878843 | c.-337_-336delCGinsAA | upstream_gene_variant | 0.43 | rifampicin | |
| rpoA | 3878845 | c.-338G>C | upstream_gene_variant | 0.47 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.47 | rifampicin | |
| rpoA | 3878869 | c.-362G>C | upstream_gene_variant | 0.44 | rifampicin | |
| rpoA | 3878873 | c.-366G>A | upstream_gene_variant | 0.42 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.4 | rifampicin | Uncertain significance |
| rpoA | 3878884 | c.-377C>G | upstream_gene_variant | 0.38 | rifampicin | |
| rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 0.38 | rifampicin | |
| rpoA | 3878893 | c.-388_-386delCACinsAG | upstream_gene_variant | 0.38 | rifampicin | |
| rpoA | 3878899 | c.-392C>T | upstream_gene_variant | 0.38 | rifampicin | |
| rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 0.37 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.34 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>C | upstream_gene_variant | 0.33 | rifampicin | |
| rpoA | 3878931 | c.-424C>T | upstream_gene_variant | 0.36 | rifampicin | |
| rpoA | 3878935 | c.-428C>T | upstream_gene_variant | 0.32 | rifampicin | |
| rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.32 | rifampicin | |
| rpoA | 3878947 | c.-440G>T | upstream_gene_variant | 0.32 | rifampicin | |
| rpoA | 3878950 | c.-443C>T | upstream_gene_variant | 0.32 | rifampicin | |
| rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 0.3 | rifampicin | |
| rpoA | 3878962 | c.-455G>C | upstream_gene_variant | 0.28 | rifampicin | |
| rpoA | 3878965 | c.-458C>G | upstream_gene_variant | 0.28 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.29 | rifampicin | Uncertain significance |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.26 | rifampicin | Uncertain significance |
| rpoA | 3878977 | c.-470C>G | upstream_gene_variant | 0.26 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.19 | rifampicin | |
| rpoA | 3879097 | c.-590C>T | upstream_gene_variant | 0.18 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.21 | rifampicin | |
| rpoA | 3879125 | c.-618T>G | upstream_gene_variant | 0.21 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.21 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.24 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.25 | rifampicin | |
| rpoA | 3879178 | c.-671T>G | upstream_gene_variant | 0.29 | rifampicin | |
| rpoA | 3879190 | c.-683C>A | upstream_gene_variant | 0.26 | rifampicin | |
| rpoA | 3879199 | c.-692C>A | upstream_gene_variant | 0.26 | rifampicin | |
| rpoA | 3879202 | c.-695T>C | upstream_gene_variant | 0.27 | rifampicin | |
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.31 | delamanid | |
| pretomanid | ||||||
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.29 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>G | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038436 | p.Ala757Ser | missense_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.22 | pyrazinamide | |
| clpC1 | 4038451 | p.Thr752Ser | missense_variant | 0.22 | pyrazinamide | |
| clpC1 | 4038455 | c.2246_2249delTGGT | frameshift_variant | 0.22 | pyrazinamide | |
| clpC1 | 4038462 | c.2242_2243insACAT | frameshift_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038474 | p.Ser744Ala | missense_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038485 | p.Gly740Lys | missense_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038491 | c.2214C>G | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038509 | c.2196C>T | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038512 | c.2193C>G | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038519 | p.Arg729Gln | missense_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038530 | c.2175G>A | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038533 | p.Arg724Lys | missense_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038538 | p.Thr723Ser | missense_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4038620 | p.Gln695Leu | missense_variant | 0.33 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.33 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.32 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.33 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>A | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4038679 | p.Pro676Ala | missense_variant | 0.38 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>T | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4038726 | p.Thr660Cys | missense_variant | 0.45 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.53 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038794 | c.1909_1911delAGCinsTCG | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038875 | c.1830C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038905 | c.1800A>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>G | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038928 | c.1777C>A | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4038929 | c.1776G>T | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4038932 | c.1773G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.51 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038980 | c.1725C>T | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039001 | c.1702_1704delAACinsGG | frameshift_variant&missense_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039043 | c.1662G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4039073 | c.1632C>G | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4039090 | c.1615C>T | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>T | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4039118 | c.1587C>G | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4039127 | p.Lys526Asn | missense_variant | 0.46 | pyrazinamide | |
| clpC1 | 4039136 | c.1569C>T | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4039141 | p.Glu522Lys | missense_variant | 0.45 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039187 | c.1518G>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039199 | c.1506C>T | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039265 | c.1440C>T | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4039271 | c.1434G>A | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039277 | c.1428C>G | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4039280 | c.1425G>C | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>G | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039295 | c.1408_1410delTCAinsGC | frameshift_variant&missense_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4039310 | c.1395A>G | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>A | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039346 | c.1359G>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039355 | c.1350G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039394 | c.1311G>C | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039406 | c.1299G>C | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.34 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039442 | c.1261_1263delCTAinsTG | frameshift_variant&synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039448 | c.1257A>G | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>A | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4039568 | p.Met379Ile | missense_variant | 0.41 | pyrazinamide | Uncertain significance |
| clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039581 | p.Thr375Ser | missense_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039601 | c.1104G>C | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039655 | c.1050G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>G | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>T | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039823 | c.882T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.33 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039855 | c.850C>T | synonymous_variant | 0.34 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4039901 | c.804C>G | synonymous_variant | 0.39 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040001 | p.His235Ala | missense_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040009 | c.696C>G | synonymous_variant | 0.4 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>G | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4040027 | c.678C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4040030 | c.675C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.37 | pyrazinamide | |
| clpC1 | 4040057 | c.648C>T | synonymous_variant | 0.41 | pyrazinamide | |
| clpC1 | 4040090 | c.615T>C | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040093 | c.612C>T | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040126 | c.579C>G | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4040135 | c.570C>G | synonymous_variant | 0.42 | pyrazinamide | |
| clpC1 | 4040144 | c.561G>C | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4040159 | c.546G>C | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.44 | pyrazinamide | |
| clpC1 | 4040168 | c.537G>C | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040200 | c.505T>C | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040204 | c.501G>C | synonymous_variant | 0.46 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4040213 | c.492T>G | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040231 | c.474C>G | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040257 | p.Ala150Thr | missense_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.56 | pyrazinamide | |
| clpC1 | 4040315 | p.Glu130Asp | missense_variant | 0.55 | pyrazinamide | |
| clpC1 | 4040326 | c.379C>T | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>A | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040345 | c.360C>G | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>C | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.48 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.47 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040419 | c.286C>T | synonymous_variant | 0.54 | pyrazinamide | |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.49 | pyrazinamide | |
| clpC1 | 4040432 | c.273C>T | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040444 | c.261C>G | synonymous_variant | 0.5 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.52 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040531 | c.174T>G | synonymous_variant | 0.45 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040540 | c.165G>C | synonymous_variant | 0.43 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.38 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>G | synonymous_variant | 0.36 | pyrazinamide | |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.35 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4040596 | c.109C>T | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>G | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4040600 | c.103_105delTTAinsCC | frameshift_variant&missense_variant | 0.29 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4040618 | c.87C>G | synonymous_variant | 0.32 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4040645 | c.60C>G | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040660 | c.45G>C | synonymous_variant | 0.31 | pyrazinamide | |
| clpC1 | 4040669 | c.36C>T | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4040681 | c.24T>G | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4040695 | c.10C>A | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4040710 | c.-6C>A | upstream_gene_variant | 0.18 | pyrazinamide | |
| clpC1 | 4040711 | c.-7G>A | upstream_gene_variant | 0.18 | pyrazinamide | |
| glpK | 4138464 | p.Gly431Ala | missense_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138472 | c.1284G>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>T | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138490 | c.1266G>T | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138494 | p.Gln421Gly | missense_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138500 | p.Arg419His | missense_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138502 | c.1254T>G | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138511 | c.1245C>T | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138514 | c.1242A>C | synonymous_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138523 | c.1233C>G | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138526 | p.Asp410Glu | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138529 | p.Val409Ala | missense_variant | 0.19 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138538 | c.1218C>G | synonymous_variant | 0.24 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138547 | c.1209C>T | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138550 | c.1206C>T | synonymous_variant | 0.21 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138556 | c.1200G>C | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138568 | c.1188A>G | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 0.2 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 0.22 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138598 | c.1158G>A | synonymous_variant | 0.23 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138625 | c.1131G>C | synonymous_variant | 0.24 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 0.24 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138634 | c.1122G>T | synonymous_variant | 0.21 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138661 | c.1095T>C | synonymous_variant | 0.21 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138682 | c.1074C>A | synonymous_variant | 0.18 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138696 | p.Pro354Thr | missense_variant | 0.17 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | ||||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| embC | 4239298 | c.-565C>T | upstream_gene_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4241134 | c.1272G>A | synonymous_variant | 0.22 | ethambutol | |
| embC | 4241135 | p.Val425Leu | missense_variant | 0.22 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
| embC | 4241141 | p.Ile427Val | missense_variant | 0.22 | ethambutol | Uncertain significance |
| embC | 4241158 | c.1296T>C | synonymous_variant | 0.24 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 0.21 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 0.22 | ethambutol | |
| embC | 4241185 | c.1323G>C | synonymous_variant | 0.21 | ethambutol | |
| embC | 4241188 | c.1326C>G | synonymous_variant | 0.19 | ethambutol | |
| embC | 4241197 | c.1335G>C | synonymous_variant | 0.19 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 0.18 | ethambutol | |
| embC | 4241215 | c.1353C>G | synonymous_variant | 0.19 | ethambutol | |
| embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4242803 | p.Val981Leu | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embA | 4244288 | c.1056C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244894 | c.1662C>G | synonymous_variant | 0.4 | ethambutol | |
| embA | 4244897 | c.1665T>G | synonymous_variant | 0.38 | ethambutol | |
| embA | 4244906 | c.1674C>G | synonymous_variant | 0.37 | ethambutol | |
| embA | 4244909 | c.1677C>A | synonymous_variant | 0.37 | ethambutol | |
| embA | 4244919 | c.1687_1689delCTCinsTG | frameshift_variant&missense_variant | 0.37 | ethambutol | Uncertain significance |
| embA | 4244930 | c.1698G>C | synonymous_variant | 0.37 | ethambutol | |
| embA | 4244933 | c.1701A>G | synonymous_variant | 0.37 | ethambutol | |
| embA | 4244945 | c.1713C>G | synonymous_variant | 0.36 | ethambutol | |
| embA | 4244959 | p.Ala576Gly | missense_variant | 0.41 | ethambutol | |
| embA | 4244980 | p.Val583Ala | missense_variant | 0.41 | ethambutol | |
| embA | 4244982 | c.1750T>C | synonymous_variant | 0.42 | ethambutol | |
| embA | 4244986 | p.Gly585Ala | missense_variant | 0.41 | ethambutol | |
| embB | 4248248 | c.1735_1737delTTCinsCG | frameshift_variant&missense_variant | 0.22 | ethambutol | |
| embB | 4248252 | p.Gly580Ala | missense_variant | 0.2 | ethambutol | |
| embB | 4248256 | c.1743C>G | synonymous_variant | 0.2 | ethambutol | |
| embB | 4248264 | p.Phe584Ser | missense_variant | 0.2 | ethambutol | |
| embB | 4248274 | c.1761C>T | synonymous_variant | 0.22 | ethambutol | |
| embB | 4248275 | c.1762_1764delACGinsGC | frameshift_variant&missense_variant | 0.22 | ethambutol | |
| embB | 4248319 | c.1806A>C | synonymous_variant | 0.17 | ethambutol | |
| embB | 4248321 | p.Gly603Ala | missense_variant | 0.17 | ethambutol | Uncertain significance |
| embB | 4248325 | c.1812G>C | synonymous_variant | 0.17 | ethambutol | |
| embB | 4248338 | c.1825C>T | synonymous_variant | 0.18 | ethambutol | |
| embB | 4248343 | c.1830G>C | synonymous_variant | 0.19 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 0.2 | ethambutol | |
| embB | 4248368 | p.Leu619Val | missense_variant | 0.18 | ethambutol | |
| embB | 4248382 | c.1869C>T | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
| embB | 4248398 | c.1885_1887delCTGinsGT | frameshift_variant&missense_variant | 0.17 | ethambutol | |
| embB | 4248407 | p.Leu632Val | missense_variant | 0.16 | ethambutol | |
| ethA | 4326788 | p.Leu229Arg | missense_variant | 1.0 | ethionamide | Uncertain significance |
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
| amikacin | Not assoc w R | |||||
| kanamycin | Not assoc w R | |||||
| whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| gid | 4407979 | p.Pro75Leu | missense_variant | 1.0 | streptomycin | Uncertain significance |
