TB-Profiler result

Run: ERR323115
Summary

Run ID: ERR323115

Sample name:

Date: 2024-04-16T07:05:00.490216

Number of reads: 291548

Percentage reads mapped: 7.38

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.91
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 924 c.924C>G synonymous_variant 1.0 isoniazid
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 933 c.933C>G synonymous_variant 1.0 isoniazid
dnaA 955 c.955_957delAGAinsCT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.96 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>T synonymous_variant 1.0 isoniazid
dnaA 993 c.993A>G synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 999 c.999C>G synonymous_variant 1.0 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
gyrB 6100 c.861G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6148 c.909C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6157 c.918C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6175 c.936G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6391 c.-911G>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6398 p.Val387Ile missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 0.96 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6727 c.-575G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.97 levofloxacin Uncertain significance
moxifloxacin
gyrA 6751 c.-551G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.91 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6850 c.-452C>T upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7162 c.-140C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7460 c.159C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7496 c.195C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7671 c.370_372delCCGinsGC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7742 c.441G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8318 c.1017C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8319 c.1018_1019delAGinsTC synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8330 c.1029C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 0.89 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.89 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8774 c.1473C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8843 c.1542G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8909 c.1608C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8952 p.Gln551Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9213 p.Thr638Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGT synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491256 c.474G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491271 c.489C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491295 c.513C>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491316 c.534C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491321 p.Ala180Val missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491541 c.759G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491571 p.Asp263Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575652 p.Arg102Pro missense_variant 0.85 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575692 c.345G>A synonymous_variant 0.95 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.95 ethionamide
isoniazid Not assoc w R - Interim
mshA 575705 c.358T>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575734 c.387T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.94 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575761 c.414C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 c.448_450delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575843 p.Arg166Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620337 c.447C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>T synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620362 c.472_474delGCCinsTG frameshift_variant&missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.93 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620670 c.780C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620709 c.819G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
hadA 731753 c.-177A>G upstream_gene_variant 0.93 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.93 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.93 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 1.0 isoniazid
nusG 734439 c.186C>G synonymous_variant 0.93 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.94 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.96 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.96 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.97 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.98 rifampicin
nusG 734499 c.246G>C synonymous_variant 0.97 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.82 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.95 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.96 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760220 c.414C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760325 c.519G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>T synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.93 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.96 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760514 c.708C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760658 c.852G>A synonymous_variant 0.97 rifampicin
rpoB 760661 c.855A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.97 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.97 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.92 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.91 rifampicin
rpoB 760754 c.948G>C synonymous_variant 0.91 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 0.91 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.92 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.93 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.93 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.97 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 1.0 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760887 p.Thr361Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.92 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.9 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.9 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.97 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.97 rifampicin
rpoB 761126 c.1320G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.96 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.97 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.96 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.96 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.96 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.95 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.93 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>T synonymous_variant 0.94 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.97 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761639 c.1833G>A synonymous_variant 1.0 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.96 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.95 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.95 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.95 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.94 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.94 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.97 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.97 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762009 c.2203C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762146 c.2340G>A synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762221 c.2415G>A synonymous_variant 0.97 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.97 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.9 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.96 rifampicin
rpoC 762854 c.-516G>C upstream_gene_variant 0.96 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 0.97 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.97 rifampicin Uncertain significance
rpoB 762929 c.3123G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.94 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.96 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.82 rifampicin
rpoC 763417 c.48C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 0.9 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 0.82 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.82 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.88 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.94 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.93 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.96 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.96 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.9 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.89 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.92 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.91 rifampicin
rpoC 764077 c.708C>G synonymous_variant 0.91 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.91 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.91 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.79 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.75 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.83 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.82 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 0.81 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.76 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.81 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.81 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.88 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.89 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.9 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.89 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.9 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.91 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.92 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.95 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.95 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.95 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.94 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.93 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765403 c.2034G>C synonymous_variant 0.95 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.95 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.95 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.95 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.97 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.97 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.95 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.93 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.96 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.94 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.94 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.91 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.91 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765577 c.2208G>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.91 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.91 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.96 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.96 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.92 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.87 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.93 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.92 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.92 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.93 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.95 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.94 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.95 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.91 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.92 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.92 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.93 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.92 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.92 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>A synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.97 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.97 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.97 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.97 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.98 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.93 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767296 c.3927C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767302 c.3933C>A synonymous_variant 0.8 rifampicin
mmpL5 775851 p.Ser877Thr missense_variant 0.53 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Leu missense_variant 0.41 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 0.51 clofazimine
bedaquiline
mmpL5 775895 c.2584_2586delATCinsCA frameshift_variant&missense_variant 0.57 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775904 c.2577G>A synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.52 clofazimine
bedaquiline
mmpL5 775910 c.2569_2571delCGGinsAA frameshift_variant&missense_variant 0.53 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775922 c.2557_2559delCTGinsTC frameshift_variant&synonymous_variant 0.43 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775951 c.2530C>T synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775955 c.2524_2526delATCinsGG frameshift_variant&missense_variant 0.36 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775961 c.2520C>G synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776081 c.2400G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776087 c.2394C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776093 c.2388C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776099 p.Thr794Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776107 c.2374C>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776126 c.2355C>T synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 776129 c.2352C>G synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 776132 c.2347_2349delGCAinsTG frameshift_variant&missense_variant 0.44 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776137 p.Ser782Ala missense_variant 0.94 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776312 c.2169A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776715 p.Lys589Pro missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776733 p.Ser583Asn missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776741 c.1740C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776744 c.1737C>G synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781559 c.-1G>C upstream_gene_variant 0.85 streptomycin
rpsL 781572 c.13_15delCAGinsAC frameshift_variant&missense_variant 0.88 streptomycin Uncertain significance
rpsL 781595 c.36T>C synonymous_variant 0.96 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.96 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.96 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>T synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>G synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.98 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rplC 800543 c.-266C>T upstream_gene_variant 0.84 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.85 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.94 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.89 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.84 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.83 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.81 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.81 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.83 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.88 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.89 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.92 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 0.92 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.91 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.92 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.92 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800921 p.Arg38Leu missense_variant 1.0 linezolid
rplC 800928 c.120C>T synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 0.96 linezolid
rplC 800964 c.156G>C synonymous_variant 0.96 linezolid
rplC 800985 c.177A>G synonymous_variant 0.96 linezolid
rplC 801003 c.195G>C synonymous_variant 0.86 linezolid
rplC 801004 c.196_198delCTGinsGC frameshift_variant&missense_variant 0.86 linezolid
rplC 801009 c.201A>C synonymous_variant 0.86 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.86 linezolid
rplC 801195 c.387G>T synonymous_variant 1.0 linezolid
rplC 801205 p.Arg133Ala missense_variant 1.0 linezolid
rplC 801220 p.Ser138Ala missense_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 0.96 linezolid
rplC 801252 c.444G>C synonymous_variant 0.96 linezolid
rplC 801264 c.456C>T synonymous_variant 0.88 linezolid
rplC 801267 c.459A>C synonymous_variant 0.94 linezolid
rplC 801270 c.462T>C synonymous_variant 0.94 linezolid
rplC 801276 c.468G>C synonymous_variant 0.94 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.93 linezolid
rplC 801285 c.477G>C synonymous_variant 0.93 linezolid
rplC 801307 c.499_501delGCCinsTG frameshift_variant&missense_variant 0.8 linezolid
fbiC 1303489 c.559C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303548 c.618G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303593 c.663G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303612 p.Leu228Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304515 p.Ala529Thr missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304643 c.1713G>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304682 c.1752C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305361 c.2431C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305381 c.2451G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1305399 c.2469A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305408 c.2478G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305420 c.2490C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305429 c.2499G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364839 c.427T>C synonymous_variant 0.9 pyrazinamide
sigE 1364845 c.433C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
sigE 1364859 c.447C>T synonymous_variant 0.9 pyrazinamide
sigE 1364862 c.450C>T synonymous_variant 0.9 pyrazinamide
sigE 1364865 c.453G>T synonymous_variant 0.9 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.9 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
sigE 1364883 c.471G>A synonymous_variant 0.9 pyrazinamide
atpE 1461132 p.Val30Ile missense_variant 0.94 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.94 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.94 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.94 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.89 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.89 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 0.9 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.9 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.95 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.91 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.95 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.95 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.91 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.9 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474284 n.629dupC non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474292 n.635_644delTTCCTCTCCGinsC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474420 n.764_769delGCGCAT non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474428 n.771C>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAGT non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673760 p.Lys107Asn missense_variant 1.0 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 0.92 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.85 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.86 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.87 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.87 ethionamide
isoniazid
inhA 1673931 c.-271C>G upstream_gene_variant 0.88 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.85 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1674399 c.198A>G synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674402 c.201C>T synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674421 c.220T>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674428 p.Gly76Asp missense_variant 0.87 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674441 c.240G>A synonymous_variant 0.88 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674444 c.243G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674477 c.276G>T synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 0.86 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674514 p.Ile105Val missense_variant 0.88 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.86 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674542 p.Ala114Glu missense_variant 0.86 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.85 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.95 ethionamide
isoniazid
inhA 1674687 c.486G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674702 c.501G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 0.95 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCT frameshift_variant&missense_variant 0.95 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674852 c.651G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674930 c.729C>T synonymous_variant 0.93 ethionamide
isoniazid
rpsA 1833589 c.48A>C synonymous_variant 0.93 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833859 c.318C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.94 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.91 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.91 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.91 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833994 c.453G>T synonymous_variant 0.91 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.87 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.88 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.89 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834123 c.582C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.86 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.83 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834225 c.684C>T synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834234 c.693G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 0.95 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.95 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.95 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.96 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.9 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.9 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.89 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.93 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.93 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.93 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.93 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.8 linezolid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155696 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.92 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518612 c.498C>G synonymous_variant 1.0 isoniazid
kasA 2518621 c.507G>A synonymous_variant 1.0 isoniazid
kasA 2518624 c.510C>G synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Phe missense_variant 1.0 isoniazid
kasA 2518697 p.Cys195Val missense_variant 1.0 isoniazid
kasA 2518705 c.591T>C synonymous_variant 1.0 isoniazid
kasA 2518708 c.594C>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518759 c.645C>T synonymous_variant 1.0 isoniazid
kasA 2518777 p.Asp221Glu missense_variant 1.0 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 1.0 isoniazid
kasA 2518787 c.673_675delCGGinsGT frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518795 c.681C>T synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518822 c.708C>A synonymous_variant 0.96 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518847 p.Leu245Met missense_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 1.0 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 1.0 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519193 c.1080_1081delGA frameshift_variant 1.0 isoniazid
kasA 2519198 c.1084_1085insAT frameshift_variant 1.0 isoniazid
kasA 2519209 c.1095C>G synonymous_variant 1.0 isoniazid
kasA 2519218 c.1104G>T synonymous_variant 1.0 isoniazid
Rv2477c 2782453 c.1590C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782480 c.1563G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783584 c.457_459delGCCinsCG frameshift_variant&synonymous_variant 0.8 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783593 c.450T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 0.84 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783634 p.Leu137Ile missense_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783847 p.Thr66Pro missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783854 c.187_189delTTCinsCG frameshift_variant&missense_variant 0.83 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783877 p.Lys56Gln missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783881 c.160_162delTTGinsAC frameshift_variant&missense_variant 0.85 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783884 c.159T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783897 p.Arg49Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783901 c.142T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783902 c.141C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783905 c.138C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2752c 3065022 c.1170G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065051 c.1141C>T synonymous_variant 0.95 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065055 c.1137T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065058 c.1134C>G synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065067 c.1125C>T synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065082 c.1110G>A synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 0.95 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065106 c.1086C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067688 c.258G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067709 c.235_237delTCGinsAGC synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067712 c.234G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067730 c.216G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067760 c.186G>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.89 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.86 para-aminosalicylic_acid
thyA 3073885 c.586_587insCG frameshift_variant 0.86 para-aminosalicylic_acid
thyA 3073890 p.Leu194Phe missense_variant 0.86 para-aminosalicylic_acid
thyA 3073891 c.579_580delCT frameshift_variant 0.86 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073926 c.546G>T synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3074196 c.276G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074199 c.273G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.8 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 0.92 para-aminosalicylic_acid
thyA 3074220 c.252A>C synonymous_variant 0.92 para-aminosalicylic_acid
lpqB 3624636 p.His92Arg missense_variant 0.92 bedaquiline
rifampicin Uncertain significance
lpqB 3624643 p.Ile90Leu missense_variant 0.93 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624674 p.Asn79Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624683 c.228G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.225A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624695 c.216C>T synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624725 c.186G>C synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625246 c.-336G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625251 c.-341C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625282 c.-372C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625312 c.-402G>T upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625318 c.-408G>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625325 p.His430Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625354 c.-444G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625357 c.-447T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625386 p.Ala410Pro missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625390 c.-480C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625741 c.-831G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625768 c.-858G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625801 c.-891G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625845 p.Ser257Thr missense_variant 0.88 bedaquiline
rifampicin
lpqB 3625846 c.-936G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625855 c.759G>A synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625864 c.748_750delCGTinsAG frameshift_variant&missense_variant 0.86 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625867 c.747A>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625882 c.-972G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625888 c.-978G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 0.71 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3626735 c.-122C>T upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 0.82 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.83 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626783 c.-170C>T upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3626792 c.-179G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626795 c.-182C>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626846 c.504G>A synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.93 bedaquiline
rifampicin Uncertain significance
mtrB 3626999 c.-386G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627005 c.-392G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627008 c.-395G>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627023 c.-410C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>T upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627263 c.-650C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627269 c.81G>T synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627277 c.73C>T synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627278 c.-665G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627305 c.43_45delGCTinsCA frameshift_variant&synonymous_variant 0.91 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627323 c.25_27delTTGinsCT frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627326 c.-713T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
fbiB 3642656 c.1122G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642692 c.1158C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642709 p.Gly392Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642711 p.Leu393Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.9 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 1.0 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 1.0 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 1.0 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 1.0 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.97 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 0.97 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.94 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.91 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.9 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.9 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.9 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.9 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.9 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 0.92 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.92 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.92 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.94 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.95 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878103 c.405A>G synonymous_variant 0.96 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.96 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 1.0 rifampicin
rpoA 3878154 c.354G>C synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878244 c.264G>A synonymous_variant 0.91 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.9 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.9 rifampicin
rpoA 3878935 c.-428C>T upstream_gene_variant 0.91 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 0.92 rifampicin
clpC1 4038302 c.2403C>G synonymous_variant 0.9 pyrazinamide
clpC1 4038310 p.Val799Leu missense_variant 0.9 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.92 pyrazinamide
clpC1 4038325 p.Val794Leu missense_variant 0.94 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038410 c.2295C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.92 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.96 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.92 pyrazinamide
clpC1 4038536 c.2169C>A synonymous_variant 0.96 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.97 pyrazinamide
clpC1 4038584 c.2121G>T synonymous_variant 0.97 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.93 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.91 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.79 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.86 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.86 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.83 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.84 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.94 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.93 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039100 c.1605C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039199 c.1506C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039361 c.1344C>A synonymous_variant 0.94 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.97 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.97 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039598 c.1107C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039601 c.1104G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039613 c.1092C>T synonymous_variant 0.98 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.98 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.96 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039943 c.762G>T synonymous_variant 0.96 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.95 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039955 c.750G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 0.96 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040015 c.690G>T synonymous_variant 0.95 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 0.94 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.94 pyrazinamide
clpC1 4040093 c.612C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040300 c.405C>T synonymous_variant 0.95 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.94 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040560 c.145C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040696 c.9A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.9 pyrazinamide
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138658 c.1098C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138685 c.1071C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138696 p.Pro354Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138697 c.1059C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138754 c.1002C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138772 c.984G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138775 c.981C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138787 c.969C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138793 c.963T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138805 c.951C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239514 c.-349A>T upstream_gene_variant 0.91 ethambutol
embC 4239518 c.-345C>T upstream_gene_variant 0.91 ethambutol
embC 4239524 c.-339C>T upstream_gene_variant 0.91 ethambutol
embC 4239526 c.-337_-336delGGinsAC upstream_gene_variant 0.91 ethambutol
embC 4239533 c.-330T>C upstream_gene_variant 0.91 ethambutol
embC 4239539 c.-324G>A upstream_gene_variant 0.91 ethambutol
embC 4239540 c.-323_-321delTTGinsCC upstream_gene_variant 0.91 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.91 ethambutol
embC 4240717 c.855T>C synonymous_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 1.0 ethambutol
embC 4240825 c.963G>A synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.82 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.85 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.87 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.87 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.87 ethambutol
embC 4241074 c.1212G>C synonymous_variant 0.87 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.87 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.77 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.83 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.83 ethambutol
embC 4241126 p.Leu422Met missense_variant 0.8 ethambutol
embC 4241551 c.1689A>T synonymous_variant 0.8 ethambutol
embC 4241560 c.1698C>G synonymous_variant 0.89 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.95 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.95 ethambutol
embC 4241593 c.1731C>G synonymous_variant 0.95 ethambutol
embC 4241614 c.1752A>C synonymous_variant 1.0 ethambutol
embC 4241626 c.1764T>C synonymous_variant 1.0 ethambutol
embC 4241635 c.1773G>C synonymous_variant 1.0 ethambutol
embC 4241644 c.1782G>C synonymous_variant 1.0 ethambutol
embC 4241648 c.1786T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4242844 c.-389A>G upstream_gene_variant 0.8 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.8 ethambutol
embC 4242855 p.Gly998Ala missense_variant 0.88 ethambutol
embA 4242862 c.-371A>G upstream_gene_variant 0.88 ethambutol
embC 4242872 p.Asp1004Thr missense_variant 0.79 ethambutol
embC 4242878 p.Thr1006Val missense_variant 0.8 ethambutol
embA 4242907 c.-326G>C upstream_gene_variant 0.75 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.8 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embA 4245077 c.1845G>C synonymous_variant 1.0 ethambutol
embA 4245083 c.1851A>C synonymous_variant 1.0 ethambutol
embA 4245089 c.1857G>C synonymous_variant 1.0 ethambutol
embB 4247467 c.954C>T synonymous_variant 0.94 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.94 ethambutol
embB 4247491 c.978G>T synonymous_variant 0.96 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.96 ethambutol
embB 4247506 c.993C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247527 c.1014G>C synonymous_variant 1.0 ethambutol
embB 4247536 c.1023C>G synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247540 p.Val343Ile missense_variant 1.0 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4248106 c.1593C>G synonymous_variant 1.0 ethambutol
embB 4248118 c.1605T>C synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.94 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.95 ethambutol
embB 4248143 c.1630_1632delTTGinsAC frameshift_variant&missense_variant 0.95 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.96 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.96 ethambutol
embB 4248170 p.Ala553Ser missense_variant 0.96 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.96 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.95 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.94 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.94 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 1.0 ethambutol Uncertain significance
embB 4248233 c.1720C>T synonymous_variant 1.0 ethambutol
embB 4248242 p.Val577Ile missense_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.96 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.96 ethambutol
embB 4248259 p.Met582Ile missense_variant 0.95 ethambutol
embB 4248269 p.Met586Gln missense_variant 0.95 ethambutol
embB 4248275 c.1762_1764delACGinsGC frameshift_variant&missense_variant 0.94 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.94 ethambutol
aftB 4267547 c.1290C>G synonymous_variant 0.83 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 0.86 ethambutol
aftB 4267567 c.1270C>T synonymous_variant 0.86 ethambutol
aftB 4267571 c.1266T>C synonymous_variant 0.8 ethambutol
aftB 4267577 c.1260C>T synonymous_variant 0.8 ethambutol Not assoc w R - Interim
aftB 4267580 c.1257G>T synonymous_variant 0.8 ethambutol
aftB 4267592 c.1243_1245delGCCinsTG frameshift_variant&missense_variant 0.8 ethambutol Uncertain significance
aftB 4267601 c.1236C>G synonymous_variant 0.86 ethambutol
aftB 4267622 c.1215G>C synonymous_variant 0.86 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.86 ethambutol