TB-Profiler result

Run: SRR1172728
Summary

Run ID: SRR1172728

Sample name:

Date: 2024-04-16T05:34:44.172880

Number of reads: 572316

Percentage reads mapped: 31.07

Median coverage: 12.0

Strain: La3

Spoligotype:

Drug-resistance: RR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.13
lineage6.2.3 West-Africa 2 RD702 0.06
La3 M.orygis None 0.1
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser450Leu Assoc w R
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.4_6delGCAinsTT Assoc w R
c.376_378delCCTinsGG Assoc w R
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1024_1026delGAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.358_360delCAGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 0.56 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761155 p.Ser450Leu missense_variant 0.28 rifampicin Assoc w R
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.85 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303954 c.1024_1026delGAAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance Mutation from literature
tlyA 1917943 c.4_6delGCAinsTT frameshift_variant&missense_variant 0.54 capreomycin Assoc w R
tlyA 1918315 c.376_378delCCTinsGG frameshift_variant&missense_variant 0.6 capreomycin Assoc w R
fbiA 3640900 c.358_360delCAGinsAC frameshift_variant&missense_variant 0.53 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.61 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.6 isoniazid
dnaA 42 c.42C>T synonymous_variant 0.65 isoniazid
dnaA 51 c.51C>T synonymous_variant 0.46 isoniazid
dnaA 558 c.558G>C synonymous_variant 0.67 isoniazid
dnaA 561 c.561C>T synonymous_variant 0.69 isoniazid
dnaA 567 c.567C>G synonymous_variant 0.73 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.76 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 0.8 isoniazid
dnaA 588 c.588A>C synonymous_variant 0.86 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.86 isoniazid
dnaA 600 c.600T>G synonymous_variant 0.86 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.85 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 649 c.649C>T synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.82 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.85 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.85 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.77 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.77 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>C synonymous_variant 0.77 isoniazid
dnaA 682 c.682T>C synonymous_variant 0.77 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.75 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.78 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.67 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.67 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.64 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.64 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.71 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.73 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.68 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.71 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.67 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 0.55 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.52 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.53 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.59 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.59 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.59 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.62 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.53 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.58 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.64 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.61 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.58 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.58 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.64 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.64 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.67 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.65 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.57 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.5 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.44 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.44 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.44 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.52 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.47 isoniazid Not assoc w R - Interim
dnaA 999 c.999C>G synonymous_variant 0.53 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.56 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.56 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.55 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.6 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.64 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.78 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.77 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.77 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.75 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.72 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.72 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.79 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.75 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.69 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.6 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.6 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.67 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.62 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.59 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.64 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.7 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.73 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.77 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.86 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.86 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.76 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.76 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.75 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.73 isoniazid
dnaA 1311 c.1311C>G synonymous_variant 0.77 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.77 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.75 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 0.75 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.8 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.8 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.67 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.62 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.62 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.62 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.67 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.71 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.75 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.76 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.78 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.85 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.8 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.74 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.7 isoniazid
dnaA 1485 c.1485A>G synonymous_variant 0.79 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.75 isoniazid
dnaA 1497 c.1497T>C synonymous_variant 0.72 isoniazid
dnaA 1506 c.1506T>G synonymous_variant 0.65 isoniazid
gyrB 5803 c.564A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 5806 c.567C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 5809 c.570C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 5812 c.573C>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 5849 c.610C>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 5863 c.624G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 5880 p.Thr214Ser missense_variant 0.44 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.65 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6250 c.1011A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.83 levofloxacin Uncertain significance
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.82 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.72 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7015 c.-287G>A upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.68 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7246 c.2007T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 7347 c.46_48delGAAinsCG frameshift_variant&missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7436 c.135C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7439 c.138C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7775 c.474C>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8090 c.789C>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8096 c.795T>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.84 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8372 c.1071G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 8387 c.1086C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8401 p.Asp367Ala missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318_1320delTTGinsCA frameshift_variant&missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.62 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.78 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.33 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.36 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.4 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.42 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.42 isoniazid
fgd1 490797 c.15G>A synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.77 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fgd1 491173 c.391C>A synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.62 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 0.83 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491340 c.558C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491535 c.753G>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>A synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
mshA 575075 c.-273T>C upstream_gene_variant 0.58 ethionamide
isoniazid Uncertain significance
mshA 575084 c.-264T>C upstream_gene_variant 0.64 ethionamide
isoniazid
mshA 575117 c.-231T>C upstream_gene_variant 0.67 ethionamide
isoniazid
mshA 575118 c.-230_-228delACGinsGC upstream_gene_variant 0.67 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCC upstream_gene_variant 0.71 ethionamide
isoniazid
mshA 575137 c.-211C>G upstream_gene_variant 0.8 ethionamide
isoniazid
mshA 575144 c.-204T>C upstream_gene_variant 0.8 ethionamide
isoniazid
mshA 575154 c.-194_-192delGTGinsCC upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575161 c.-187T>C upstream_gene_variant 0.82 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.67 ethionamide
isoniazid
mshA 575542 c.195C>A synonymous_variant 0.67 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.71 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.77 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.77 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.83 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.83 ethionamide
isoniazid
mshA 575587 c.240C>G synonymous_variant 0.83 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.83 ethionamide
isoniazid
mshA 575623 c.276C>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.72 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.72 ethionamide
isoniazid
mshA 575665 c.318G>A synonymous_variant 0.74 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.68 ethionamide
isoniazid
mshA 575695 c.348C>A synonymous_variant 0.63 ethionamide
isoniazid
mshA 575701 c.354G>A synonymous_variant 0.56 ethionamide
isoniazid
mshA 575704 c.357T>G synonymous_variant 0.56 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.6 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.68 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.71 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.72 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575755 c.408G>A synonymous_variant 0.81 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.81 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.88 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.88 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575809 c.462C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.94 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575833 c.486C>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 575845 c.498C>T synonymous_variant 0.8 ethionamide
isoniazid Not assoc w R - Interim
mshA 575864 c.517T>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.73 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.6 ethionamide
isoniazid
mshA 575917 p.Asp190Glu missense_variant 0.57 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.54 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.5 ethionamide
isoniazid
ccsA 619584 c.-307A>T upstream_gene_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 619594 c.-297G>T upstream_gene_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 619609 c.-282G>C upstream_gene_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>T synonymous_variant 0.73 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.77 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.76 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620424 c.534G>C synonymous_variant 0.74 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.68 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.68 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>G synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 0.46 capreomycin
amikacin
kanamycin
Rv0565c 656402 p.Ala357Thr missense_variant 0.7 ethionamide
Rv0565c 656412 c.1059T>C synonymous_variant 0.67 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.73 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 0.75 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.81 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.76 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.76 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.76 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.73 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.73 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.67 ethionamide Not assoc w R - Interim
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.55 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.67 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.81 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.81 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.82 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.82 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.82 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.77 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.83 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.67 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.64 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.6 ethionamide
Rv0565c 657372 c.99G>C synonymous_variant 0.48 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.48 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.4 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 0.4 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 0.44 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.47 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.5 ethionamide
Rv0565c 657600 c.-132_-131delCA upstream_gene_variant 0.5 ethionamide
Rv0565c 657606 c.-136T>G upstream_gene_variant 0.5 ethionamide
Rv0565c 657607 c.-138_-137insCA upstream_gene_variant 0.5 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.76 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.88 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.89 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.88 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.62 ethionamide
hadA 731717 c.-213T>G upstream_gene_variant 0.9 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.91 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.92 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.97 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.91 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.88 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.88 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.85 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.88 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.89 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.89 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.84 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.81 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.8 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.72 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.76 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.74 isoniazid
nusG 734352 c.99T>C synonymous_variant 0.55 rifampicin
nusG 734360 p.Ala36Val missense_variant 0.57 rifampicin Uncertain significance
nusG 734370 c.117A>G synonymous_variant 0.62 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.65 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.76 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.78 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.81 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.81 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.85 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.85 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.84 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.82 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.83 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.84 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.84 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.88 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.88 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.82 rifampicin
nusG 734814 c.561G>C synonymous_variant 0.53 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.68 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>C synonymous_variant 0.8 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.84 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.89 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.89 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.89 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.95 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.95 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.93 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.92 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.88 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.84 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.87 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.85 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.82 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.85 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.83 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.78 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.78 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.84 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.85 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.85 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.88 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.91 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.94 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.94 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.9 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.81 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.73 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.72 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.72 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.74 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.67 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.69 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.79 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.76 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.76 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.65 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.71 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.75 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.77 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.66 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.72 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.72 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.81 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.89 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.78 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.72 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.78 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.79 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.83 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.85 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.85 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.86 rifampicin
rpoB 761373 p.Val523His missense_variant 0.88 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.75 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.74 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.53 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.73 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.82 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.93 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.88 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.88 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.76 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.84 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 0.67 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.67 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.69 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.71 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.75 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.77 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.76 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.77 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.67 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.71 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.75 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.89 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.82 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.82 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.83 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.83 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.83 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.8 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.79 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.79 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.79 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.79 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.82 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.85 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.88 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.9 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.93 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.92 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.92 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.95 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.94 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.95 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.96 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.96 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.9 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.9 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.9 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.88 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.88 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.9 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.9 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.91 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.95 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.95 rifampicin
rpoC 762512 c.-858C>G upstream_gene_variant 0.79 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.86 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.81 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.75 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.75 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.68 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.64 rifampicin Uncertain significance
rpoB 762810 c.3004_3006delGCCinsTG frameshift_variant&missense_variant 0.55 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.55 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.9 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.85 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.89 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.96 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.91 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.84 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.82 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.82 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.81 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.72 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.72 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 0.69 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.72 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.71 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.67 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.72 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.77 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.82 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.79 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.79 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.82 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.85 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.85 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.85 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.92 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.92 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.93 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.93 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.89 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.85 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.85 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.85 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.82 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.87 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.87 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.88 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.84 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.85 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.83 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.87 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.92 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.9 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.87 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.93 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.94 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.88 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.92 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.91 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.88 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.86 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.86 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.87 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.88 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.79 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.83 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.83 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.83 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.88 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.79 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.88 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.82 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.78 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.67 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.69 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.69 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.81 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.81 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.8 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.76 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.79 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.73 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.73 rifampicin
rpoC 765292 c.1923G>C synonymous_variant 0.76 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 0.76 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.76 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.78 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.8 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 0.86 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765364 c.1995G>A synonymous_variant 0.9 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.94 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.92 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.89 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.85 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.84 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.83 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.83 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.82 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.8 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.81 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.85 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.85 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.84 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.83 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.81 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.8 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.79 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.79 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.82 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.83 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.88 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.86 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.92 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.95 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.96 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 0.6 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.73 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.69 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.79 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.77 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.77 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.79 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.79 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.82 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.85 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.83 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.87 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.83 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.8 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.8 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.81 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.69 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.77 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.75 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.83 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.75 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.82 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.84 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.84 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.84 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.83 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.83 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.8 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.82 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.87 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.84 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.85 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.95 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.94 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.94 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.92 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.84 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.75 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.67 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.38 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.46 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.46 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.55 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
mmpL5 775961 c.2520C>G synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.5 clofazimine
bedaquiline
mmpL5 775973 c.2506_2508delTTGinsCC frameshift_variant&missense_variant 0.55 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775981 p.Leu834Met missense_variant 0.64 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.6 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776030 c.2451G>A synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 776672 c.1809G>C synonymous_variant 0.46 clofazimine
bedaquiline
mmpL5 776675 c.1806G>A synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 776684 c.1797G>A synonymous_variant 0.46 clofazimine
bedaquiline
mmpL5 776687 p.Trp598Phe missense_variant 0.4 clofazimine
bedaquiline
mmpL5 776695 p.Val596Ile missense_variant 0.42 clofazimine
bedaquiline
mmpL5 776738 c.1743C>T synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 776744 c.1735_1737delCGCinsAA frameshift_variant&missense_variant 0.62 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776756 p.Asp575Glu missense_variant 0.62 clofazimine
bedaquiline
mmpL5 777101 c.1380C>G synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 777110 c.1371T>G synonymous_variant 0.69 clofazimine
bedaquiline
mmpL5 777115 p.Met456Leu missense_variant 0.69 clofazimine
bedaquiline
mmpL5 777116 c.1365C>T synonymous_variant 0.69 clofazimine
bedaquiline
mmpL5 777133 p.Val450Ile missense_variant 0.65 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.81 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 777212 c.1267_1269delGCCinsAG frameshift_variant&missense_variant 0.62 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777215 c.1266C>G synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 777218 c.1263G>A synonymous_variant 0.62 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.57 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.71 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.68 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.68 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.86 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.86 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.87 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.88 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.83 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.83 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.8 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.82 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.84 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.81 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.82 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.8 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.8 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.79 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.74 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.88 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.88 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.86 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.89 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.89 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.83 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.82 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.82 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.85 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.83 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.82 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.79 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.85 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.96 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.96 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.92 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.95 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.92 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.86 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.86 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.86 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.86 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.88 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.89 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.92 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.89 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.88 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.88 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.89 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.9 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.88 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.88 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.88 linezolid
rplC 800814 c.6A>G synonymous_variant 0.91 linezolid
rplC 800817 c.9A>T synonymous_variant 0.94 linezolid
rplC 800844 c.36T>C synonymous_variant 0.88 linezolid
rplC 800865 c.57A>G synonymous_variant 0.78 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.8 linezolid
rplC 800907 c.99C>G synonymous_variant 0.67 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.46 linezolid
rplC 801132 c.324T>C synonymous_variant 0.46 linezolid
rplC 801147 c.339T>C synonymous_variant 0.59 linezolid
rplC 801150 c.342G>C synonymous_variant 0.59 linezolid
rplC 801153 c.345G>C synonymous_variant 0.56 linezolid
rplC 801156 c.348T>A synonymous_variant 0.58 linezolid
rplC 801168 c.360C>G synonymous_variant 0.57 linezolid
rplC 801171 c.363A>G synonymous_variant 0.57 linezolid
rplC 801174 c.366T>C synonymous_variant 0.62 linezolid
rplC 801195 c.387G>C synonymous_variant 0.65 linezolid
rplC 801207 c.399C>T synonymous_variant 0.64 linezolid
rplC 801246 c.438C>T synonymous_variant 0.5 linezolid
rplC 801249 c.441T>C synonymous_variant 0.5 linezolid
rplC 801255 c.447C>T synonymous_variant 0.5 linezolid
rplC 801300 c.492C>G synonymous_variant 0.42 linezolid
rplC 801309 c.501C>G synonymous_variant 0.47 linezolid
rplC 801312 c.504G>C synonymous_variant 0.4 linezolid
rplC 801321 c.513C>T synonymous_variant 0.5 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.5 linezolid
rplC 801339 c.531T>C synonymous_variant 0.47 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.47 linezolid
rplC 801348 c.540T>G synonymous_variant 0.67 linezolid
rplC 801357 c.549T>C synonymous_variant 0.7 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.78 linezolid
rplC 801402 c.594T>C synonymous_variant 0.75 linezolid
rplC 801405 c.597T>C synonymous_variant 0.75 linezolid
rplC 801423 c.615G>C synonymous_variant 0.68 linezolid
rplC 801426 c.618C>G synonymous_variant 0.64 linezolid
rplC 801427 p.Met207Val missense_variant 0.64 linezolid
rplC 801438 c.630T>C synonymous_variant 0.68 linezolid
rplC 801442 p.Ile212Val missense_variant 0.61 linezolid
fbiC 1303489 c.559C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303497 c.567G>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304161 p.Arg411Ser missense_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304187 c.1257T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fbiC 1304535 c.1605G>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.88 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>A synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1305252 c.2322G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305372 c.2442G>A synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 0.64 clofazimine Not assoc w R - Interim
pretomanid
delamanid
sigE 1365042 c.630G>C synonymous_variant 0.67 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.8 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.73 pyrazinamide
atpE 1460816 c.-229T>C upstream_gene_variant 0.81 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.87 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.88 bedaquiline
atpE 1460852 c.-193C>G upstream_gene_variant 0.86 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.86 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.86 bedaquiline
atpE 1460861 c.-184C>G upstream_gene_variant 0.86 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.79 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.69 bedaquiline
atpE 1460897 c.-148A>C upstream_gene_variant 0.69 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.57 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.6 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.6 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.59 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.59 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.75 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.81 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.74 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.72 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.6 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.57 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.59 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.56 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.91 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.84 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473653 n.-5_2delTGTGTTTinsGTGTAA non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474958 n.1301A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.77 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
inhA 1673523 c.-679G>T upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.6 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.83 ethionamide
isoniazid
inhA 1673580 c.-622T>G upstream_gene_variant 0.82 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.78 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.8 ethionamide
isoniazid
fabG1 1673710 p.Leu91Ile missense_variant 0.77 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.72 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.67 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.62 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.62 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.62 ethionamide
isoniazid
fabG1 1673890 p.Ala151Ser missense_variant 0.9 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.86 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.86 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.87 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.88 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.88 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.96 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.95 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.67 ethionamide
isoniazid
inhA 1674114 c.-88T>A upstream_gene_variant 0.73 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1674126 c.-76G>C upstream_gene_variant 0.76 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.84 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1674156 c.-46C>G upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1674171 c.-31T>C upstream_gene_variant 0.64 ethionamide
isoniazid
inhA 1674504 c.303C>G synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.82 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.83 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.8 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.81 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674723 c.522C>T synonymous_variant 0.89 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674738 c.537C>G synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 0.86 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 0.86 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674753 c.552G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.87 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.86 ethionamide
isoniazid
inhA 1674855 c.654C>G synonymous_variant 0.86 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674864 c.663C>T synonymous_variant 0.83 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.84 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.85 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 0.92 ethionamide
isoniazid
rpsA 1833532 c.-10A>C upstream_gene_variant 0.47 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.68 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.82 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.83 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.76 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.74 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.67 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.67 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.71 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.76 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.75 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.78 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.79 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.78 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.78 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.79 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.78 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.81 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.8 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.6 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.59 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.74 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.75 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.8 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.77 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834510 c.969C>T synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.84 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.77 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.83 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.95 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.96 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.95 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.94 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.67 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.67 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.7 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.68 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.67 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.69 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.67 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.67 linezolid
tlyA 1917929 c.-11T>C upstream_gene_variant 0.58 capreomycin
tlyA 1917937 c.-3_-2insC upstream_gene_variant 0.5 capreomycin
tlyA 1917940 p.Val1Met missense_variant 0.5 capreomycin
tlyA 1917951 c.12T>C synonymous_variant 0.57 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.65 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.73 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.69 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.69 capreomycin Not assoc w R - Interim
tlyA 1917996 c.57A>G synonymous_variant 0.69 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.69 capreomycin
tlyA 1918310 p.Asn124Ser missense_variant 0.6 capreomycin
tlyA 1918323 c.384G>C synonymous_variant 0.62 capreomycin
tlyA 1918326 c.387G>C synonymous_variant 0.53 capreomycin
tlyA 1918330 p.Leu131Val missense_variant 0.57 capreomycin
tlyA 1918346 p.Ala136Val missense_variant 0.57 capreomycin
tlyA 1918352 p.Gly138Asp missense_variant 0.53 capreomycin
tlyA 1918356 c.417C>G synonymous_variant 0.57 capreomycin
tlyA 1918359 c.420A>G synonymous_variant 0.57 capreomycin
tlyA 1918362 c.423G>C synonymous_variant 0.57 capreomycin
bacA 2064972 c.-244T>C upstream_gene_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.79 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101756 c.1287G>C synonymous_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2101765 c.1278C>G synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>A synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>G synonymous_variant 0.8 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101774 c.1269T>C synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.8 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>A synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.71 ethionamide
delamanid
isoniazid
ndh 2101963 c.1080G>A synonymous_variant 0.71 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101966 c.1077T>G synonymous_variant 0.71 ethionamide
delamanid
isoniazid
ndh 2101972 c.1071G>C synonymous_variant 0.72 ethionamide
delamanid
isoniazid
ndh 2101988 p.Ala352Asp missense_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2101993 c.1050A>G synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2102233 c.810G>A synonymous_variant 0.64 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102302 c.741G>C synonymous_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2102623 c.420C>G synonymous_variant 0.75 ethionamide
delamanid
isoniazid
ndh 2102638 c.405A>C synonymous_variant 0.78 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 0.67 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102695 c.348C>T synonymous_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>T synonymous_variant 0.54 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 0.45 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>C synonymous_variant 0.35 ethionamide
delamanid
isoniazid
katG 2155677 c.435C>G synonymous_variant 0.81 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.81 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.88 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.88 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.94 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.94 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.93 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.93 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.91 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.91 isoniazid
PPE35 2169840 p.Gly258Asp missense_variant 1.0 pyrazinamide Not assoc w R
pncA 2289913 c.-672T>C upstream_gene_variant 0.62 pyrazinamide
pncA 2289925 c.-684T>C upstream_gene_variant 0.72 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.74 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.71 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.71 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 0.71 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.95 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.95 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.95 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.95 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.95 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.89 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.89 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 0.88 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.87 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 0.87 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.87 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.97 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.91 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.9 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.85 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.7 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.9 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.92 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.85 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.86 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.87 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.83 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.79 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.65 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.9 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.91 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.92 isoniazid
kasA 2518474 c.360G>A synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518483 c.369C>G synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.92 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.92 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.94 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.93 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.95 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.94 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.94 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.88 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.88 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.83 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.83 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.79 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.86 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.83 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.79 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.62 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.67 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.62 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.71 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.7 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.71 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.78 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.79 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.81 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.9 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.9 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.93 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.96 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.96 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.92 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.92 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.85 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.8 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.78 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.77 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.75 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.75 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.78 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.71 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.77 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.77 isoniazid
kasA 2518951 c.837G>C synonymous_variant 0.77 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.79 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.75 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.75 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.7 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.76 isoniazid
kasA 2519108 c.994_996delGATinsCG frameshift_variant&missense_variant 0.76 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.79 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.73 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.87 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.86 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.71 isoniazid
kasA 2519196 p.Thr361Ser missense_variant 0.64 isoniazid
ahpC 2726251 p.Gly20Ala missense_variant 0.67 isoniazid Uncertain significance
ahpC 2726255 c.63T>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ahpC 2726258 c.66C>T synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ahpC 2726303 c.111T>C synonymous_variant 0.73 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.69 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 0.69 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.69 isoniazid
ahpC 2726322 c.130_132delCCAinsGC frameshift_variant&missense_variant 0.69 isoniazid Uncertain significance
ahpC 2726330 c.138G>A synonymous_variant 0.75 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 0.77 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.91 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
ahpC 2726564 c.372C>G synonymous_variant 0.82 isoniazid Not assoc w R - Interim
ahpC 2726591 c.399C>G synonymous_variant 0.82 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.82 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.9 isoniazid
ahpC 2726601 p.Ile137Leu missense_variant 0.91 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.88 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.91 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.87 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.78 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.75 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.75 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.74 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.68 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.68 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.68 isoniazid
ahpC 2726717 c.525A>G synonymous_variant 0.53 isoniazid
folC 2746390 c.1209G>C synonymous_variant 0.64 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.64 para-aminosalicylic_acid
folC 2746414 c.1183_1185delGAGinsCA frameshift_variant&missense_variant 0.73 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.73 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.73 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.7 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 0.67 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.86 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.87 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 0.81 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747101 c.498G>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 0.71 para-aminosalicylic_acid
folC 2747264 p.Gly112Ala missense_variant 0.73 para-aminosalicylic_acid
folC 2747266 c.333C>T synonymous_variant 0.67 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.8 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.75 para-aminosalicylic_acid
folC 2747302 c.297A>C synonymous_variant 0.84 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.74 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.67 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.65 para-aminosalicylic_acid
Rv2477c 2782441 c.1602G>A synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.44 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782894 c.1149C>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.88 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.73 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.86 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.82 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.81 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784441 c.-399G>A upstream_gene_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
ribD 2987026 p.Ala63Gly missense_variant 0.57 para-aminosalicylic_acid
ribD 2987033 c.195C>G synonymous_variant 0.62 para-aminosalicylic_acid
ribD 2987042 c.204A>G synonymous_variant 0.67 para-aminosalicylic_acid
ribD 2987046 p.Val70Ile missense_variant 0.71 para-aminosalicylic_acid
ribD 2987092 p.Val85Ala missense_variant 0.71 para-aminosalicylic_acid
ribD 2987105 c.267C>G synonymous_variant 0.65 para-aminosalicylic_acid
ribD 2987108 c.270T>C synonymous_variant 0.65 para-aminosalicylic_acid
Rv2680 2996360 p.Met86Leu missense_variant 0.64 capreomycin
Rv2681 2996368 c.-371T>C upstream_gene_variant 0.64 capreomycin
Rv2681 2996374 c.-365G>C upstream_gene_variant 0.5 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 0.43 capreomycin
Rv2681 2996380 c.-359C>G upstream_gene_variant 0.43 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 0.43 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 0.43 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>G upstream_gene_variant 0.43 capreomycin
Rv2681 2996401 c.-338T>C upstream_gene_variant 0.46 capreomycin
Rv2681 2996404 c.-335T>C upstream_gene_variant 0.46 capreomycin
Rv2680 2996408 p.Leu102Met missense_variant 0.46 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.46 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.46 capreomycin
Rv2752c 3064995 c.1197C>G synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>G synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065007 c.1185G>C synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065013 c.1179G>C synonymous_variant 0.54 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065018 p.Asn392His missense_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065022 c.1170G>A synonymous_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065028 c.1162_1164delGTGinsAC frameshift_variant&missense_variant 0.64 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065040 c.1152C>G synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065183 p.Ser337Ala missense_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065190 p.Ile334Met missense_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065196 c.996T>C synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>G synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065223 c.969T>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>C synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 0.64 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065925 p.Ala89Gly missense_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 0.78 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065946 p.Gly82Ala missense_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCC frameshift_variant&missense_variant 0.88 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065988 c.204A>G synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.77 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066003 c.189C>T synonymous_variant 0.69 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin
isoniazid
Rv2752c 3066009 c.183G>C synonymous_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.72 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.67 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066093 c.99T>C synonymous_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.62 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066351 c.-160G>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066357 c.-166G>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066369 c.-180_-178delAGCinsGCG upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.6 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067325 c.621A>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067462 c.484C>T synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.81 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067510 c.436C>T synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.72 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.67 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.74 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.76 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.8 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.8 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.85 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.82 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.85 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.78 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.71 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.73 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.72 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.75 para-aminosalicylic_acid
thyA 3073812 c.660C>G synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073815 c.657G>A synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3073824 c.648A>G synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.78 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073872 c.598_600delATCinsGG frameshift_variant&missense_variant 0.67 para-aminosalicylic_acid
thyA 3073890 c.580_582delTTGinsCA frameshift_variant&missense_variant 0.58 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.58 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073941 c.531C>T synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073983 c.489C>T synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.63 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 0.53 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.53 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3074423 p.Pro17Ala missense_variant 0.5 para-aminosalicylic_acid
thyA 3074427 c.45T>A synonymous_variant 0.46 para-aminosalicylic_acid
ald 3087680 c.861G>C synonymous_variant 0.82 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.83 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.83 cycloserine
lpqB 3623356 p.Leu519Ile missense_variant 0.75 bedaquiline
rifampicin
lpqB 3623360 c.1551A>G synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623363 c.1548T>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623366 c.1545T>G synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623369 c.1542G>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623372 c.1539G>T synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623379 p.Ala511Asn missense_variant 0.75 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3623417 c.1494A>C synonymous_variant 0.73 bedaquiline
rifampicin
lpqB 3623987 c.924G>C synonymous_variant 0.73 bedaquiline
rifampicin
lpqB 3623990 c.921G>C synonymous_variant 0.73 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623993 c.918C>T synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3624014 c.897T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624041 p.Glu290Asp missense_variant 0.83 bedaquiline
rifampicin
lpqB 3624050 c.861C>G synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624077 c.834G>A synonymous_variant 0.69 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624185 c.726C>T synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3624194 c.717C>G synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 0.5 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 0.56 bedaquiline
rifampicin
lpqB 3624404 c.507G>T synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624407 c.504C>T synonymous_variant 0.67 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624410 c.501C>T synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 0.71 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624437 c.474G>A synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624461 c.450C>G synonymous_variant 0.6 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 0.55 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 0.75 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.76 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.69 bedaquiline
rifampicin Uncertain significance
lpqB 3625054 c.-144C>G upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625060 c.-150G>T upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>C upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3625087 c.1525_1527delGCCinsTG frameshift_variant&missense_variant 0.54 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625093 p.Glu507Asp missense_variant 0.56 bedaquiline
rifampicin
lpqB 3625099 c.-189C>G upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.59 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625510 c.-600T>C upstream_gene_variant 0.37 bedaquiline
rifampicin
lpqB 3625513 c.-603G>C upstream_gene_variant 0.4 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 0.42 bedaquiline
rifampicin
lpqB 3625525 c.-615G>C upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625528 c.-618G>T upstream_gene_variant 0.45 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.52 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.61 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.59 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.66 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.65 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625636 c.978C>G synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.73 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.72 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.74 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3625755 p.Ala287Thr missense_variant 0.72 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625777 c.-867C>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3625797 p.Val273Met missense_variant 0.72 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625843 c.-933C>G upstream_gene_variant 0.72 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626154 c.460C>T synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626155 c.457_459delGCGinsTC frameshift_variant&missense_variant 0.75 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626158 c.456C>T synonymous_variant 0.75 bedaquiline
rifampicin
mtrB 3626170 c.444T>C synonymous_variant 0.75 bedaquiline
rifampicin
mtrB 3626179 c.435A>G synonymous_variant 0.69 bedaquiline
rifampicin
mtrB 3626185 c.429T>G synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626188 c.424_426delTCTinsAC frameshift_variant&missense_variant 0.7 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626194 c.420T>C synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626203 c.411G>A synonymous_variant 0.7 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.86 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrA 3626869 c.481C>T synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626876 c.-263A>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626912 c.-299T>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627065 c.-452G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627071 c.279G>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3627146 c.204C>T synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627167 c.-554T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.87 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.84 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.81 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.81 bedaquiline
rifampicin
fbiB 3640866 c.-669T>C upstream_gene_variant 0.5 clofazimine
pretomanid
delamanid
fbiA 3640871 p.Ala110Gly missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiB 3640878 c.-657T>C upstream_gene_variant 0.56 clofazimine
pretomanid
delamanid
fbiB 3640899 c.-636G>C upstream_gene_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>G upstream_gene_variant 0.47 clofazimine
pretomanid
delamanid
fbiB 3641622 p.Ser30Gly missense_variant 0.75 clofazimine
pretomanid
delamanid
fbiB 3641627 c.93C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiB 3641642 c.108G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiB 3641645 c.111A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiB 3641654 c.120A>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3641663 c.129T>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3642587 p.Met351Ile missense_variant 0.58 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>T synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiB 3642609 c.1075_1076delAGinsTC synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiB 3642614 c.1080C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiB 3642617 c.1083C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
alr 3841001 c.420A>G synonymous_variant 0.77 cycloserine
alr 3841010 c.411A>G synonymous_variant 0.8 cycloserine
alr 3841017 p.Leu135Glu missense_variant 0.8 cycloserine
alr 3841022 c.399C>G synonymous_variant 0.8 cycloserine
alr 3841028 c.393G>C synonymous_variant 0.8 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.8 cycloserine
alr 3841037 c.384G>C synonymous_variant 0.75 cycloserine
rpoA 3877515 c.993G>C synonymous_variant 0.62 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.82 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.83 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.84 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.9 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.83 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.85 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.78 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.74 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.68 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.64 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.62 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.67 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.65 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.58 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.58 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.55 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.67 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.72 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.85 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.83 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.8 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878055 c.453A>G synonymous_variant 0.79 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.79 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.79 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.79 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.79 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 0.79 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.85 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.87 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.81 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.86 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.88 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.89 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.93 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.94 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.89 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.85 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.86 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.84 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.85 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.85 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.82 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.8 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.79 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.82 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.79 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.75 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.64 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.8 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.87 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.87 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.88 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.94 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.94 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.89 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.9 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.79 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.78 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.74 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.73 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.75 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.73 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.65 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.57 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.57 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.68 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.74 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.68 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.7 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.71 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.71 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.71 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.76 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.77 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.83 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.8 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.79 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.77 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.76 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.8 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.81 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.86 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.86 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.77 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.62 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.6 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.54 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.54 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.86 delamanid
pretomanid
ddn 3986646 c.-198_-196delCTCinsTG upstream_gene_variant 0.86 delamanid
pretomanid
clpC1 4038239 c.2466T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 0.87 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.81 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 0.69 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.81 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.88 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.88 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.8 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.87 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.87 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.87 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.87 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.88 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.88 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.87 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.88 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.83 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.79 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.83 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038530 c.2175G>A synonymous_variant 0.89 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.86 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.79 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.75 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.79 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.78 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.81 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.85 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.85 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.85 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.89 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.87 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.87 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.83 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.85 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.87 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.89 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.89 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.87 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.85 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.97 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.83 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.79 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.73 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.79 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.83 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.88 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.89 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.95 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.91 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.81 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.83 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039718 c.987C>A synonymous_variant 0.83 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.89 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.57 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.59 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.62 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.61 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.62 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.62 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.62 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.86 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.89 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 0.91 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.8 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.8 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.92 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.92 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.89 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.86 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.89 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.89 pyrazinamide
clpC1 4040321 c.384C>T synonymous_variant 0.89 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.84 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.83 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.9 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040450 c.255A>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.79 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.92 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.94 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.94 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 0.94 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040706 c.-4_-3delAC upstream_gene_variant 0.83 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.83 pyrazinamide
panD 4044105 c.177G>C synonymous_variant 0.53 pyrazinamide
panD 4044117 c.165G>C synonymous_variant 0.56 pyrazinamide
panD 4044120 c.162A>C synonymous_variant 0.56 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 0.56 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 0.56 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 0.64 pyrazinamide
panD 4044682 c.-401C>A upstream_gene_variant 0.6 pyrazinamide
panD 4044688 c.-407T>C upstream_gene_variant 0.6 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 0.6 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 0.6 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 0.6 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.75 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.69 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.73 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.78 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.88 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.82 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.82 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.8 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.72 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.75 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.8 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.71 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.64 pyrazinamide
panD 4044941 c.-660G>C upstream_gene_variant 0.81 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 0.86 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.92 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 0.93 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.87 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.89 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.89 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.91 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.91 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.91 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.89 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.82 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.74 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.74 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.71 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.76 pyrazinamide
glpK 4138565 c.1191G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>A synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>A synonymous_variant 0.73 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.8 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139126 c.630G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139135 c.619_621delGATinsAC frameshift_variant&synonymous_variant 0.69 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139143 c.613T>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139195 c.561G>T synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139198 c.558C>G synonymous_variant 0.82 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139207 c.549T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.159C>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Gln missense_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139615 c.141G>A synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139651 c.103_105delCACinsGG frameshift_variant&missense_variant 0.74 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139675 c.81C>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139684 c.72C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139687 c.69C>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240178 c.316T>C synonymous_variant 0.62 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.65 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embC 4240216 c.354T>C synonymous_variant 0.47 ethambutol
embC 4240219 c.357C>G synonymous_variant 0.47 ethambutol
embC 4240222 c.360G>C synonymous_variant 0.47 ethambutol
embC 4240229 c.367_369delCTGinsAC frameshift_variant&missense_variant 0.47 ethambutol
embC 4240232 p.Gln124Val missense_variant 0.47 ethambutol
embC 4240249 p.Asp129Glu missense_variant 0.6 ethambutol
embC 4240258 c.396T>G synonymous_variant 0.77 ethambutol
embC 4240654 c.792C>G synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embC 4240660 c.798C>G synonymous_variant 0.54 ethambutol
embC 4240669 c.807G>C synonymous_variant 0.54 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.54 ethambutol Not assoc w R
embC 4240677 p.Gly272Ala missense_variant 0.5 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.63 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.67 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.68 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.81 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.87 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.83 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.83 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.79 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.76 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.75 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.78 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.78 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.76 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.76 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.76 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.81 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.86 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.85 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.85 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.85 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.77 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.77 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.69 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.69 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.75 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.8 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.8 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.82 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.82 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.81 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.8 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.79 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.77 ethambutol
embC 4241179 c.1317G>A synonymous_variant 0.76 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.67 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embC 4241218 c.1356G>C synonymous_variant 0.54 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.6 ethambutol
embC 4241394 p.Lys511Ser missense_variant 0.81 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.86 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.86 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.71 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.75 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.69 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.65 ethambutol
embC 4241500 c.1638A>C synonymous_variant 0.62 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.62 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.62 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.67 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.7 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>G synonymous_variant 0.65 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.61 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 0.56 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.56 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.58 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.64 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.7 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.77 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.74 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.74 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.77 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.76 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.75 ethambutol
embC 4241747 p.Val629Leu missense_variant 0.7 ethambutol
embC 4241750 p.Leu630Val missense_variant 0.7 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.7 ethambutol
embC 4241770 c.1908T>C synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embC 4241791 c.1929G>C synonymous_variant 0.58 ethambutol
embC 4241794 c.1932C>G synonymous_variant 0.54 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.5 ethambutol
embA 4242742 c.-491C>G upstream_gene_variant 0.69 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.75 ethambutol
embA 4242754 c.-479G>C upstream_gene_variant 0.77 ethambutol
embA 4242772 c.-461G>C upstream_gene_variant 0.76 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.8 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.77 ethambutol
embA 4242802 c.-431G>C upstream_gene_variant 0.77 ethambutol
embA 4242820 c.-413G>C upstream_gene_variant 0.69 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.69 ethambutol
embA 4242832 c.-401A>C upstream_gene_variant 0.75 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.75 ethambutol
embC 4242841 c.2979C>T synonymous_variant 0.75 ethambutol Not assoc w R - Interim
embA 4242844 c.-389A>G upstream_gene_variant 0.75 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.75 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.77 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.75 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.77 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.76 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.78 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.73 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.74 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.71 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.69 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.77 ethambutol
embA 4245222 c.1990_1992delTATinsCG frameshift_variant&missense_variant 0.76 ethambutol Uncertain significance
embA 4245248 c.2016G>C synonymous_variant 0.76 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.73 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embA 4245693 p.Ile821Val missense_variant 0.92 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.91 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.83 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.79 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.73 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.69 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.71 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.69 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.71 ethambutol
embA 4245785 c.2553G>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.73 ethambutol Uncertain significance
embB 4245812 c.-702G>C upstream_gene_variant 0.79 ethambutol
embA 4245813 c.2581_2583delCCCinsGG frameshift_variant&missense_variant 0.79 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 0.79 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.79 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.88 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.94 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.94 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.94 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.94 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.91 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.92 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.94 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.94 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.95 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.93 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.92 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.92 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.93 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.93 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.87 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.83 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.76 ethambutol Uncertain significance
embB 4246367 c.-147C>T upstream_gene_variant 0.74 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.71 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.68 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.72 ethambutol Not assoc w R - Interim
embB 4246400 c.-114G>C upstream_gene_variant 0.77 ethambutol
embB 4247059 c.546C>A synonymous_variant 0.64 ethambutol
embB 4247068 c.555T>C synonymous_variant 0.64 ethambutol Not assoc w R - Interim
embB 4247074 c.561G>T synonymous_variant 0.64 ethambutol
embB 4247095 c.582G>T synonymous_variant 0.64 ethambutol
embB 4247098 c.585C>G synonymous_variant 0.64 ethambutol
embB 4247101 c.588G>C synonymous_variant 0.64 ethambutol
embB 4247105 p.Pro198Ala missense_variant 0.64 ethambutol
embB 4247110 c.597G>C synonymous_variant 0.64 ethambutol
embB 4247111 c.598C>T synonymous_variant 0.64 ethambutol
embB 4247114 p.Ala201Thr missense_variant 0.64 ethambutol Uncertain significance
embB 4247117 c.604_606delGTCinsCG frameshift_variant&missense_variant 0.64 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.66 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.7 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.73 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.71 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.72 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.73 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.62 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.64 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.73 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.91 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.92 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.92 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.92 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.92 ethambutol
embB 4247815 c.1302C>G synonymous_variant 1.0 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.89 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.89 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.81 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.81 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.81 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.84 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.85 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.84 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.84 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.89 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.83 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.82 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.8 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.9 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.86 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.8 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.8 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.83 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.86 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.86 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.86 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.81 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.79 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.79 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.73 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.67 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.67 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.65 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.64 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.64 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.61 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.64 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.71 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.88 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.84 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.81 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.79 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.75 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.77 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.77 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.76 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.77 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.86 ethambutol
embB 4248382 c.1869C>G synonymous_variant 0.83 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.85 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 0.68 ethambutol
embB 4248410 c.1897_1899delTTCinsCG frameshift_variant&missense_variant 0.65 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.69 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.73 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.73 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.67 ethambutol
embB 4249384 c.2871G>T synonymous_variant 0.6 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.65 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.65 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.65 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.61 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.61 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.67 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.62 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.7 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.72 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.6 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.6 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.64 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.62 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.62 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.64 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.69 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 0.69 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.68 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.62 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.71 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.73 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.8 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.88 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.87 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.87 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.92 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.92 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.92 ethambutol
ubiA 4268969 p.Leu289Val missense_variant 0.54 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 0.62 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.62 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.65 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.68 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.68 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.65 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.65 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.65 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.72 ethambutol