TB-Profiler result

Run: SRR10315751
Summary

Run ID: SRR10315751

Sample name:

Date: 2024-10-05T03:29:54.825798

Number of reads: 4192837

Percentage reads mapped: 16.78

Median coverage: 106.0

Strain: lineage4.8

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.8 Euro-American (mainly T) RD219 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser450Leu Assoc w R
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.Met306Val Assoc w R
pyrazinamide pncA p.Ser59Pro Assoc w R
streptomycin rpsL p.Lys43Arg Assoc w R
rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1484G>T Assoc w R
capreomycin rrs n.1484G>T Assoc w R
kanamycin rrs n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.1742delT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1747dupG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761155 p.Ser450Leu missense_variant 0.5 rifampicin Assoc w R
rpsL 781687 p.Lys43Arg missense_variant 0.58 streptomycin Assoc w R
fbiC 1304671 c.1742delT frameshift_variant 0.21 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304676 c.1747dupG frameshift_variant 0.21 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.15 streptomycin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.18 amikacin Assoc w R
capreomycin Assoc w R
kanamycin Assoc w R
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
pncA 2289067 p.Ser59Pro missense_variant 1.0 pyrazinamide Assoc w R
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 371 p.Pro124Leu missense_variant 1.0 isoniazid Not assoc w R
gyrB 6326 p.Ser363Ala missense_variant 0.16 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.17 levofloxacin
moxifloxacin
gyrB 6663 p.Phe475Tyr missense_variant 0.17 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrB 6737 p.Thr500Ala missense_variant 0.41 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6742 c.-560A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6749 p.Ala504Ser missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrB 6764 p.Leu509Phe missense_variant 0.41 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.35 levofloxacin
moxifloxacin
gyrB 6815 p.Lys526Gln missense_variant 0.71 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
nusG 734421 c.168A>C synonymous_variant 0.19 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.21 rifampicin
nusG 734443 p.Ala64Thr missense_variant 0.26 rifampicin
nusG 734448 c.195C>T synonymous_variant 0.24 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.25 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.25 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
nusG 734463 c.210G>C synonymous_variant 0.24 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734484 c.231C>T synonymous_variant 0.26 rifampicin
nusG 734505 c.252G>T synonymous_variant 0.26 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.16 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.27 rifampicin
rpoB 760112 c.306T>G synonymous_variant 0.25 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.28 rifampicin Uncertain significance
rpoB 760133 c.327C>G synonymous_variant 0.24 rifampicin
rpoB 760139 c.333A>C synonymous_variant 0.27 rifampicin
rpoB 760140 p.Pro112Ser missense_variant 0.26 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.42 rifampicin
rpoB 760181 c.375T>G synonymous_variant 0.43 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760185 c.379C>T synonymous_variant 0.31 rifampicin
rpoB 760199 c.393C>G synonymous_variant 0.44 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.35 rifampicin Uncertain significance
rpoB 760283 c.477G>A synonymous_variant 0.37 rifampicin
rpoB 760298 c.492G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.31 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.29 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.28 rifampicin
rpoB 760317 c.511_513delAGCinsTCG synonymous_variant 0.28 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.32 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.33 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.32 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.34 rifampicin
rpoB 760356 p.Thr184Ser missense_variant 0.38 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760368 c.562_563delTCinsAG synonymous_variant 0.4 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.4 rifampicin Uncertain significance
rpoB 760382 c.576G>C synonymous_variant 0.39 rifampicin
rpoB 760400 c.594G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760407 p.Ser201Gly missense_variant 0.29 rifampicin Uncertain significance
rpoB 760412 c.606C>T synonymous_variant 0.3 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760659 p.Ser285Thr missense_variant 0.15 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.24 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.25 rifampicin
rpoB 760931 c.1125C>G synonymous_variant 0.26 rifampicin
rpoB 760940 c.1134G>C synonymous_variant 0.28 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760949 c.1143C>T synonymous_variant 0.28 rifampicin
rpoB 760958 c.1152G>C synonymous_variant 0.28 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.3 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.29 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.37 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761003 c.1197C>G synonymous_variant 0.32 rifampicin
rpoB 761006 c.1200C>T synonymous_variant 0.32 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.41 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.5 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.51 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 0.42 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.47 rifampicin
rpoB 761234 c.1428G>T synonymous_variant 0.43 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 0.38 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.35 rifampicin
rpoB 761288 c.1482G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761537 c.1731C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761549 c.1743G>C synonymous_variant 0.22 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.25 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 0.25 rifampicin
rpoB 761655 p.Ala617Ser missense_variant 0.27 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.25 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.22 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.24 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.16 rifampicin
rpoB 761694 p.Ile630Val missense_variant 0.18 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 0.16 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762002 c.2196C>G synonymous_variant 0.46 rifampicin
rpoB 762003 p.Asn733Gln missense_variant 0.52 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762026 c.2220G>C synonymous_variant 0.54 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.55 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762084 p.Ala760Pro missense_variant 0.15 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.71 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 0.28 rifampicin
rpoB 762128 c.2322G>C synonymous_variant 0.44 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.26 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.4 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.7 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762156 p.Val784Ile missense_variant 0.68 rifampicin
rpoB 762161 c.2355C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762189 p.Ile795Val missense_variant 0.51 rifampicin
rpoB 762209 c.2403C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.38 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.31 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.29 rifampicin
rpoB 762278 c.2472C>T synonymous_variant 0.15 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.33 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 0.28 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.28 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.23 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762858 p.Thr1018Ser missense_variant 0.24 rifampicin
rpoB 762863 c.3057T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762881 p.Met1025Ile missense_variant 0.26 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.53 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.55 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.19 rifampicin
rpoC 763013 c.-357C>G upstream_gene_variant 0.38 rifampicin
rpoB 763014 p.Met1070Leu missense_variant 0.18 rifampicin
rpoB 763017 p.Gln1071Glu missense_variant 0.18 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.6 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.56 rifampicin Not assoc w R
rpoC 763034 c.-336C>T upstream_gene_variant 0.37 rifampicin
rpoB 763038 p.Thr1078Ala missense_variant 0.2 rifampicin
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.61 rifampicin
rpoC 763067 c.-303C>G upstream_gene_variant 0.32 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.36 rifampicin
rpoB 763077 p.Val1091Asn missense_variant 0.21 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.53 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.22 rifampicin
rpoC 763160 c.-210G>C upstream_gene_variant 0.33 rifampicin
rpoB 763161 p.Leu1119Ile missense_variant 0.14 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763170 p.Leu1122Met missense_variant 0.16 rifampicin
rpoC 763363 c.-7G>A upstream_gene_variant 0.13 rifampicin
rpoC 763411 c.42T>C synonymous_variant 0.32 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763430 c.61_63delAGGinsCGC synonymous_variant 0.34 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.34 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.56 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.58 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.57 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.56 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.58 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>G synonymous_variant 0.15 rifampicin
rpoC 763603 c.234C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763622 p.Ala85Ser missense_variant 0.16 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763642 c.273G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 0.32 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.27 rifampicin
rpoC 763708 c.339G>T synonymous_variant 0.29 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.29 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>T synonymous_variant 0.26 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.27 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.27 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.16 rifampicin
rpoC 763796 p.Met143Leu missense_variant 0.23 rifampicin
rpoC 763801 c.432C>T synonymous_variant 0.21 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763867 c.498C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763872 p.Gly168Ala missense_variant 0.18 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.21 rifampicin
rpoC 763879 c.510A>C synonymous_variant 0.23 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.23 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.23 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 0.23 rifampicin
rpoC 763910 p.Leu181Ile missense_variant 0.24 rifampicin
rpoC 763921 c.552G>C synonymous_variant 0.24 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 0.22 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.2 rifampicin
rpoC 763961 p.Arg198Asn missense_variant 0.14 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.19 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.18 rifampicin
rpoC 764002 c.633C>T synonymous_variant 0.17 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764134 c.765C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764149 c.780G>C synonymous_variant 0.29 rifampicin
rpoC 764157 p.Lys263Ile missense_variant 0.27 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.27 rifampicin
rpoC 764164 p.Ile265Met missense_variant 0.27 rifampicin
rpoC 764165 p.Glu266Arg missense_variant 0.27 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.37 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.45 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.45 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.44 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.45 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.47 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 0.5 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.5 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.5 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.5 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.5 rifampicin
rpoC 764269 c.900G>T synonymous_variant 0.49 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764308 c.939G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>T synonymous_variant 0.65 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.57 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764368 c.999C>T synonymous_variant 0.48 rifampicin
rpoC 764371 c.1002G>T synonymous_variant 0.53 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 0.54 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.58 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.15 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.54 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.16 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764506 c.1137C>T synonymous_variant 0.36 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.39 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>G synonymous_variant 0.46 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.25 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.26 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.44 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.2 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764706 p.Leu446His missense_variant 0.18 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764719 c.1350G>A synonymous_variant 0.46 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.46 rifampicin
rpoC 764785 c.1416C>G synonymous_variant 0.43 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.54 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.41 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.4 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764840 p.Ile491Val missense_variant 0.53 rifampicin Uncertain significance
rpoC 764843 p.Ala492Asn missense_variant 0.36 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.27 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.29 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.28 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.28 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.24 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.24 rifampicin Uncertain significance
rpoC 764917 c.1548G>C synonymous_variant 0.24 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 0.23 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.2 rifampicin
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.18 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.21 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.17 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765064 c.1695C>T synonymous_variant 0.18 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.22 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.2 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.15 rifampicin
rpoC 765874 c.2505G>C synonymous_variant 0.17 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.18 rifampicin Uncertain significance
rpoC 765890 p.Arg841Lys missense_variant 0.18 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765907 c.2538G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.19 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.16 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.17 rifampicin
rpoC 765955 c.2586C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 0.15 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.17 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.17 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.29 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.29 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.3 rifampicin
rpoC 766910 p.Ile1181Val missense_variant 0.33 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.35 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 0.29 rifampicin
rpoC 766934 p.Glu1189Ser missense_variant 0.3 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.32 rifampicin
rpoC 766951 c.3582G>C synonymous_variant 0.32 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766969 c.3600C>T synonymous_variant 0.28 rifampicin
rpoC 766978 c.3609C>A synonymous_variant 0.32 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 767017 c.3648C>G synonymous_variant 0.43 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 0.42 rifampicin
rpoC 767093 c.3724_3726delAGCinsTCG synonymous_variant 0.39 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Ile missense_variant 0.46 rifampicin
rpoC 767113 c.3744G>C synonymous_variant 0.4 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 767173 c.3804C>G synonymous_variant 0.24 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.2 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.2 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781572 p.Gln5Asn missense_variant 0.15 streptomycin
rpsL 781592 c.33T>C synonymous_variant 0.15 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.15 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.15 streptomycin
rpsL 781605 p.Ile16Ala missense_variant 0.16 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.16 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.16 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 0.25 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.28 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.24 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.42 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.22 streptomycin
rpsL 781706 c.147T>G synonymous_variant 0.2 streptomycin
rpsL 781709 c.150G>T synonymous_variant 0.23 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.36 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.16 streptomycin
rpsL 781725 p.Lys56Arg missense_variant 0.16 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.16 streptomycin
rpsL 781733 c.174_176delGAGinsC frameshift_variant&synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781738 p.Gln60Arg missense_variant 0.2 streptomycin
rpsL 781740 c.182_183insAT frameshift_variant 0.26 streptomycin Uncertain significance
rpsL 781751 c.192G>C synonymous_variant 0.46 streptomycin
rpsL 781754 c.195G>T synonymous_variant 0.22 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.47 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.22 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.26 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.4 streptomycin
rpsL 781803 p.Val82Ile missense_variant 0.19 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.58 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.58 streptomycin
rpsL 781829 c.270G>T synonymous_variant 0.41 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.56 streptomycin
rpsL 781856 c.297C>T synonymous_variant 0.41 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>C synonymous_variant 0.43 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.55 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.54 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.51 streptomycin
rpsL 781898 c.339A>G synonymous_variant 0.42 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.43 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.41 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.44 streptomycin
rplC 800633 c.-176T>C upstream_gene_variant 0.27 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.21 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.18 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.22 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.23 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 0.24 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.23 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.22 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.23 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.22 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.18 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.2 linezolid
Rv1129c 1253535 p.Phe334Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
fbiC 1304613 c.1683T>C synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304649 c.1719C>T synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304660 p.Tyr577Phe missense_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304662 p.Ser578Thr missense_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>T synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304682 c.1752C>G synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304712 c.1782C>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.14 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.58 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.58 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.18 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.13 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.15 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.15 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.76 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468_470delGATinsAGAG non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.74 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>A non_coding_transcript_exon_variant 0.76 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.78 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472518 n.673G>C non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472544 n.699C>G non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.26 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.34 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.16 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.16 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472670 n.824_825insTAG non_coding_transcript_exon_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472678 n.833T>A non_coding_transcript_exon_variant 0.17 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472682 n.837_838delTTinsAC non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472684 n.841_846delGATCCG non_coding_transcript_exon_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.17 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.17 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.18 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.19 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.24 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.61 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 0.56 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472844 n.999_1004delCGCGTCinsAAGCCG non_coding_transcript_exon_variant 0.59 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472858 n.1013G>C non_coding_transcript_exon_variant 0.58 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472862 n.1017T>C non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472863 n.1018T>C non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472878 n.1033G>A non_coding_transcript_exon_variant 0.59 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.21 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111_1113delTCAinsCTG non_coding_transcript_exon_variant 0.81 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.16 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.2 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.81 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.22 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.14 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.81 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.15 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.75 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473791 n.134A>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1473792 n.135C>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1473802 n.145C>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1473803 n.146G>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1473804 n.147T>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473814 n.157A>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473830 n.173T>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsCA non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474220 n.563G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_633delCCTinsGCGCCA non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474294 n.638_646delCTCTCCGGA non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474310 n.655dupG non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474415 n.758_781delCCACACGCGCATACGCGCGTGTGAinsT non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474439 n.782A>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1052_1054delGTGinsAGA non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474716 n.1059_1060delAAinsGAG non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.15 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.32 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474804 n.1147C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474927 n.1271delC non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1474931 n.1274G>A non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475406 n.1749T>G non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1475414 n.1757G>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1475422 n.1765A>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475481 n.1824C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475482 n.1825A>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948_1951delATATinsTC non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475629 n.1973dupA non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid
rrl 1475636 n.1979_1982delATCCinsGAG non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsAGT non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475766 n.2109G>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 0.16 capreomycin
linezolid Uncertain significance
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475882 n.2225C>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid Uncertain significance
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.63 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.44 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.5 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.6 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.74 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.8 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833589 c.48A>C synonymous_variant 0.18 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.19 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.19 pyrazinamide
rpsA 1833607 c.66T>C synonymous_variant 0.2 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.2 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.19 pyrazinamide
rpsA 1833623 p.Lys28Ala missense_variant 0.19 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.41 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 0.39 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.41 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 0.4 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.41 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.33 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.33 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.34 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.31 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.31 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.34 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.42 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.37 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.39 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.42 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.48 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.46 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.51 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 0.46 pyrazinamide
rpsA 1833838 c.297G>A synonymous_variant 0.45 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.52 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.53 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.49 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.6 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.58 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.15 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.46 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.17 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.53 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.4 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.58 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.62 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.2 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.42 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.21 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.48 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.5 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.62 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.59 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.46 pyrazinamide
rpsA 1834108 c.567C>A synonymous_variant 0.48 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834151 p.Asn204His missense_variant 0.29 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.28 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.28 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.28 pyrazinamide
rpsA 1834167 c.628_629delAC frameshift_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834172 c.631_632insGG frameshift_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
rpsA 1834210 c.669C>T synonymous_variant 0.5 pyrazinamide
rpsA 1834219 c.678C>G synonymous_variant 0.14 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.31 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.24 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.28 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTTG synonymous_variant 0.18 pyrazinamide
rpsA 1834264 c.723G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834286 c.745_746delTCinsAG synonymous_variant 0.21 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.42 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.55 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.34 pyrazinamide
rpsA 1834307 p.Asp256Lys missense_variant 0.42 pyrazinamide
rpsA 1834310 p.Glu257Pro missense_variant 0.21 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.36 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 0.28 pyrazinamide
rpsA 1834340 p.Met267Leu missense_variant 0.34 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>T synonymous_variant 0.57 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.54 pyrazinamide
rpsA 1834378 c.837T>G synonymous_variant 0.44 pyrazinamide
rpsA 1834384 c.843A>G synonymous_variant 0.34 pyrazinamide
rpsA 1834395 p.Arg285His missense_variant 0.25 pyrazinamide
rpsA 1834399 p.His286Gln missense_variant 0.37 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.56 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.59 pyrazinamide
rpsA 1834456 c.915T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.35 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.58 pyrazinamide
rpsA 1834474 c.933C>T synonymous_variant 0.44 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
rpsA 1834486 p.Glu315Asp missense_variant 0.19 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.51 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.48 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.51 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.51 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.48 pyrazinamide
rpsA 1834557 p.Ala339Gly missense_variant 0.43 pyrazinamide
rpsA 1834570 c.1029C>T synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
rpsA 1834574 p.Met345Leu missense_variant 0.44 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.41 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.41 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.43 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834650 p.Thr370Asn missense_variant 0.31 pyrazinamide
rpsA 1834653 p.Glu371Ala missense_variant 0.29 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.28 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.31 pyrazinamide
rpsA 1834688 c.1147_1149delAGTinsTCG synonymous_variant 0.31 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.26 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.27 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.19 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.14 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2154769 p.Asp448Ala missense_variant 1.0 isoniazid Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517917 c.-198G>C upstream_gene_variant 0.23 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.25 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.25 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.22 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.2 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.18 isoniazid
kasA 2517986 c.-129C>T upstream_gene_variant 0.15 isoniazid
Rv2477c 2783181 p.Leu288Val missense_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0 ethionamide Uncertain significance
mtrB 3625729 c.885A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627068 c.282T>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrB 3627074 c.-461G>T upstream_gene_variant 0.17 rifampicin
bedaquiline
mtrB 3627092 c.-479C>G upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627128 p.Asp74Glu missense_variant 0.15 rifampicin
bedaquiline
mtrB 3627131 c.-518C>G upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrB 3627134 c.-521C>G upstream_gene_variant 0.16 rifampicin
bedaquiline
mtrB 3627139 c.-526T>C upstream_gene_variant 0.15 rifampicin
bedaquiline
mtrB 3627140 c.-527G>C upstream_gene_variant 0.15 rifampicin
bedaquiline
mtrB 3627143 c.-530G>T upstream_gene_variant 0.15 rifampicin
bedaquiline
alr 3840764 c.657G>C synonymous_variant 1.0 cycloserine
rpoA 3877613 p.Ile299Val missense_variant 0.14 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.19 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.24 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 0.19 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>T synonymous_variant 0.21 rifampicin
rpoA 3877685 c.823C>T synonymous_variant 0.14 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877701 c.807G>T synonymous_variant 0.25 rifampicin
rpoA 3877704 c.804G>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3877731 c.777G>T synonymous_variant 0.32 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.35 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.34 rifampicin
rpoA 3877758 c.750G>C synonymous_variant 0.17 rifampicin
rpoA 3877761 c.747G>C synonymous_variant 0.15 rifampicin
rpoA 3877764 p.Ala248Gly missense_variant 0.15 rifampicin
rpoA 3877770 c.738A>C synonymous_variant 0.17 rifampicin
rpoA 3877773 c.735G>T synonymous_variant 0.16 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877794 c.714G>T synonymous_variant 0.25 rifampicin
rpoA 3877800 c.708G>C synonymous_variant 0.17 rifampicin
rpoA 3877803 c.705G>A synonymous_variant 0.16 rifampicin
rpoA 3877815 c.693C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877821 c.687C>A synonymous_variant 0.21 rifampicin
rpoA 3877824 c.684G>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877833 c.675C>G synonymous_variant 0.17 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>T synonymous_variant 0.31 rifampicin
rpoA 3877842 c.666A>C synonymous_variant 0.33 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877854 c.652_654delTTGinsCTC synonymous_variant 0.17 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.18 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.19 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.16 rifampicin
rpoA 3877881 c.627G>T synonymous_variant 0.17 rifampicin
rpoA 3877896 p.Pro204Ala missense_variant 0.16 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.27 rifampicin
rpoA 3877902 c.606C>T synonymous_variant 0.14 rifampicin
rpoA 3877905 c.603A>C synonymous_variant 0.17 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.3 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 0.15 rifampicin
rpoA 3877936 p.Lys191Arg missense_variant 0.16 rifampicin
rpoA 3877938 c.570C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>C synonymous_variant 0.17 rifampicin
rpoA 3877968 c.540C>G synonymous_variant 0.19 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.19 rifampicin Uncertain significance
rpoA 3878202 c.306G>C synonymous_variant 0.18 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878217 p.Leu97Val missense_variant 0.23 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.21 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.24 rifampicin
rpoA 3878251 c.256_257delTCinsAG synonymous_variant 0.17 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.24 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.29 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.28 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 0.36 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>T synonymous_variant 0.26 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.39 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>C synonymous_variant 0.29 rifampicin
rpoA 3878334 c.174T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3878343 c.165C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.29 rifampicin
rpoA 3878358 c.150C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3878361 c.147G>T synonymous_variant 0.2 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.33 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.33 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.16 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.16 rifampicin
rpoA 3878397 c.111G>C synonymous_variant 0.16 rifampicin
rpoA 3878400 c.108T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878406 c.102G>C synonymous_variant 0.3 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 0.17 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.18 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.17 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.16 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.16 rifampicin
rpoA 3879097 c.-590C>T upstream_gene_variant 0.15 rifampicin
rpoA 3879121 c.-614T>C upstream_gene_variant 0.17 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.17 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 0.17 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.17 rifampicin
rpoA 3879145 c.-638G>C upstream_gene_variant 0.18 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.18 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.18 rifampicin
rpoA 3879166 c.-659C>G upstream_gene_variant 0.18 rifampicin
rpoA 3879175 c.-668C>T upstream_gene_variant 0.18 rifampicin
rpoA 3879182 c.-676_-675delAAinsCG upstream_gene_variant 0.19 rifampicin
rpoA 3879190 c.-683C>A upstream_gene_variant 0.2 rifampicin
rpoA 3879202 c.-695T>A upstream_gene_variant 0.16 rifampicin
ddn 3986615 c.-229C>G upstream_gene_variant 0.18 pretomanid
delamanid
ddn 3986616 c.-228_-227delAGinsTC upstream_gene_variant 0.2 pretomanid
delamanid
ddn 3986621 c.-223G>C upstream_gene_variant 0.19 pretomanid
delamanid
clpC1 4038740 c.1965G>C synonymous_variant 0.31 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>T synonymous_variant 0.37 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.4 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.41 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 0.42 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.45 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 0.45 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>T synonymous_variant 0.51 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 0.58 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.51 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.56 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.56 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.57 pyrazinamide
clpC1 4038926 c.1779G>T synonymous_variant 0.55 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.59 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.61 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.61 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4038997 c.1708T>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039007 c.1698G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.55 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.4 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4039082 c.1623C>T synonymous_variant 0.36 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.42 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039094 c.1611C>A synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4039097 c.1608G>T synonymous_variant 0.37 pyrazinamide
clpC1 4039100 c.1605C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 0.42 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.45 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.43 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.46 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.39 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 0.4 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.4 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.41 pyrazinamide
clpC1 4039217 c.1488G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4039279 p.Val476Ile missense_variant 0.46 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 0.47 pyrazinamide
clpC1 4039289 c.1416T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.48 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 0.49 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 0.49 pyrazinamide
clpC1 4039347 p.Arg453Lys missense_variant 0.45 pyrazinamide
clpC1 4039355 c.1350G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039359 p.Ser449Asn missense_variant 0.44 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.41 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.37 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.34 pyrazinamide Uncertain significance
clpC1 4039427 p.Glu426Asp missense_variant 0.31 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.32 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.28 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039466 c.1239T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.2 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039478 c.1227G>A synonymous_variant 0.19 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.19 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039499 c.1206G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.27 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039526 c.1179G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.29 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.4 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.29 pyrazinamide
clpC1 4039570 c.1135delAinsCAC frameshift_variant&missense_variant 0.28 pyrazinamide
clpC1 4039574 c.1131G>A synonymous_variant 0.31 pyrazinamide
clpC1 4039575 c.1128_1129delTG frameshift_variant 0.3 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039604 c.1101G>A synonymous_variant 0.16 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.6 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.57 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.48 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.55 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.56 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.56 pyrazinamide
clpC1 4039763 c.942C>A synonymous_variant 0.53 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.57 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.58 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.56 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.62 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.46 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039840 p.Leu289Met missense_variant 0.14 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.18 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039898 c.805_807delCTCinsTTG synonymous_variant 0.64 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.21 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.24 pyrazinamide
clpC1 4039925 c.780C>G synonymous_variant 0.45 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.68 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.47 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039967 p.Gln246His missense_variant 0.21 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039991 c.714G>T synonymous_variant 0.34 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 0.21 pyrazinamide
clpC1 4040001 p.His235Ser missense_variant 0.2 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.36 pyrazinamide
clpC1 4040009 p.Ala232Asp missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040013 p.Gln231Ala missense_variant 0.17 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.18 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.34 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.52 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 0.19 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.5 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4040051 c.654C>G synonymous_variant 0.26 pyrazinamide
clpC1 4040057 c.648C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4040066 c.639G>C synonymous_variant 0.39 pyrazinamide
clpC1 4040069 c.636G>T synonymous_variant 0.37 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4040093 c.612C>G synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4040108 c.597G>C synonymous_variant 0.16 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.2 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.27 pyrazinamide
clpC1 4040429 c.274_276delTTGinsCTC synonymous_variant 0.27 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.28 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.31 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.31 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.29 pyrazinamide
clpC1 4040495 c.210C>T synonymous_variant 0.31 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.35 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.33 pyrazinamide
clpC1 4040540 c.165G>C synonymous_variant 0.32 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 0.29 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.25 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.25 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.25 pyrazinamide
clpC1 4040573 c.132T>G synonymous_variant 0.25 pyrazinamide
clpC1 4040582 c.123G>T synonymous_variant 0.24 pyrazinamide
clpC1 4040585 c.120A>G synonymous_variant 0.24 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.24 pyrazinamide
clpC1 4040594 c.111G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.24 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.24 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.24 pyrazinamide
clpC1 4040612 c.93G>A synonymous_variant 0.23 pyrazinamide
clpC1 4040615 c.90C>G synonymous_variant 0.23 pyrazinamide
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
aftB 4269159 c.-323G>C upstream_gene_variant 0.15 ethambutol
aftB 4269171 c.-335C>G upstream_gene_variant 0.23 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.28 ethambutol
ubiA 4269191 p.Ser215Gly missense_variant 0.27 ethambutol
ubiA 4269199 p.Ser212Tyr missense_variant 0.26 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.26 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.25 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.25 ethambutol Not assoc w R - Interim
ubiA 4269225 c.609C>T synonymous_variant 0.25 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 0.25 ethambutol
aftB 4269237 c.-401C>G upstream_gene_variant 0.25 ethambutol
aftB 4269240 c.-404G>C upstream_gene_variant 0.25 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.24 ethambutol
aftB 4269258 c.-422C>G upstream_gene_variant 0.24 ethambutol
ubiA 4269271 p.Val188Ala missense_variant 0.23 ethambutol Uncertain significance
aftB 4269291 c.-455A>G upstream_gene_variant 0.24 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R