Run ID: ERR108471
Sample name:
Date: 2024-04-15T23:30:53.725090
Number of reads: 329782
Percentage reads mapped: 7.18
Median coverage: 1.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 0.99 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.94 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | katG | p.Ser140Asn | Uncertain significance | Mutation from literature |
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.508_510delGTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
fbiC | c.601_603delATGinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491290 | c.508_510delGTGinsAC | frameshift_variant&missense_variant | 0.92 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303531 | c.601_603delATGinsCC | frameshift_variant&missense_variant | 0.93 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
katG | 2155693 | p.Ser140Asn | missense_variant | 1.0 | isoniazid | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 558 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 570 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 576 | c.576G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 588 | c.588A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 594 | c.594C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 600 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 627 | c.627G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 633 | c.633T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 645 | c.645A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 660 | c.660G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 672 | c.672T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 681 | c.681G>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 682 | c.682_684delTTGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 687 | c.687C>T | synonymous_variant | 0.94 | isoniazid | |
dnaA | 693 | c.693A>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 702 | c.702C>T | synonymous_variant | 0.96 | isoniazid | |
dnaA | 705 | c.705A>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 771 | c.771A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 783 | c.783C>T | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 793 | c.793_795delGTAinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 798 | c.798C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 888 | c.888C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 894 | c.894G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 903 | c.903C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 909 | c.909A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 912 | c.912T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 933 | c.933C>G | synonymous_variant | 1.0 | isoniazid | |
gyrB | 5812 | c.573C>G | synonymous_variant | 0.8 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5818 | c.579G>C | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.86 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5839 | c.600C>G | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 5863 | c.624G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5865 | p.Thr209Ser | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5869 | c.630C>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5873 | c.634A>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5882 | p.Gln215Ala | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5893 | c.654C>G | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5902 | c.663A>G | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6086 | p.Thr283Pro | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6151 | c.912C>T | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6181 | c.942C>A | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6184 | c.945C>G | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6187 | c.948C>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6203 | p.Ser322Ala | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6208 | c.969G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6215 | p.Ser326Thr | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6323 | c.1085_1086insGTCT | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 6327 | c.1090_1093delGAAC | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6334 | c.-968G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>C | upstream_gene_variant | 0.85 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6658 | c.-644G>C | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6721 | c.1482C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6724 | c.-578G>C | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6794 | p.Ile519Leu | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6798 | p.Gly520Ala | missense_variant | 0.96 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrB | 6800 | p.Lys521Arg | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6808 | c.1569C>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7397 | c.96G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7406 | c.105G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7421 | c.120G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7433 | c.132G>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7721 | c.420G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7778 | c.477G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7790 | c.489G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7796 | c.495G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7841 | c.540C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7847 | c.546G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7853 | c.552C>T | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7886 | c.585T>C | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7890 | c.589C>T | synonymous_variant | 0.91 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8327 | c.1026C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | c.1039_1041delGCGinsTC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>C | synonymous_variant | 0.88 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8609 | c.1308G>C | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>T | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8639 | c.1338G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8645 | c.1344C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8849 | c.1548C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8900 | c.1599G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>T | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.94 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>A | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9038 | c.1737C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9065 | c.1764C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9145 | p.Arg615Gln | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9147 | p.Gly616Ser | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9153 | p.Thr618Gln | missense_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9203 | c.1902G>A | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9213 | p.Thr638Glu | missense_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.81 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9236 | c.1935G>C | synonymous_variant | 0.83 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.87 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9248 | c.1947G>C | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9254 | c.1953C>G | synonymous_variant | 0.89 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9281 | c.1980C>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9287 | c.1986G>A | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9356 | c.2055G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9362 | c.2061C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9368 | c.2067G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9413 | c.2112G>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9419 | c.2118T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9420 | p.Ile707Glu | missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
fgd1 | 491259 | c.477T>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.96 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491289 | c.507C>T | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.68 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491307 | c.525C>T | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491310 | c.528C>G | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491320 | p.Ala180Gln | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.71 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491370 | c.588C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491523 | c.741G>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491559 | c.777G>A | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491563 | c.781_783delAGCinsTCG | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491574 | c.792C>T | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491605 | c.823C>T | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491628 | c.846G>A | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575714 | p.Tyr123Asn | missense_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575728 | c.381C>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.87 | ethionamide | |
isoniazid | ||||||
mshA | 575744 | p.Ala133Thr | missense_variant | 1.0 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575804 | c.457_459delTCGinsAGC | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575818 | c.471G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575842 | c.495G>C | synonymous_variant | 0.97 | ethionamide | |
isoniazid | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.97 | ethionamide | |
isoniazid | ||||||
mshA | 575878 | c.531A>C | synonymous_variant | 0.97 | ethionamide | |
isoniazid | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.97 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
ccsA | 620569 | c.679_681delGGAinsCG | frameshift_variant&missense_variant | 0.75 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620583 | c.693G>C | synonymous_variant | 0.89 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620589 | c.699G>C | synonymous_variant | 0.9 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620598 | c.708C>G | synonymous_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620604 | c.714C>T | synonymous_variant | 0.92 | capreomycin | |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620607 | c.717T>C | synonymous_variant | 0.92 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620619 | c.729G>T | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620622 | c.732G>C | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620652 | c.762C>G | synonymous_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620658 | c.768C>A | synonymous_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620679 | c.789C>G | synonymous_variant | 0.92 | capreomycin | |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620698 | p.Val270Ile | missense_variant | 0.89 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.7 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
hadA | 731729 | c.-201C>T | upstream_gene_variant | 0.83 | isoniazid | |
hadA | 731732 | c.-198G>C | upstream_gene_variant | 0.85 | isoniazid | |
hadA | 731753 | c.-177A>C | upstream_gene_variant | 0.91 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.94 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.94 | isoniazid | |
hadA | 731810 | c.-120G>C | upstream_gene_variant | 0.94 | isoniazid | |
hadA | 731813 | c.-117C>T | upstream_gene_variant | 0.94 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.95 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731860 | c.-70C>G | upstream_gene_variant | 1.0 | isoniazid | |
nusG | 734373 | c.120_121insC | frameshift_variant | 1.0 | rifampicin | |
nusG | 734394 | c.141C>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.94 | rifampicin | |
nusG | 734421 | c.168A>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734439 | c.186C>G | synonymous_variant | 0.97 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.97 | rifampicin | |
nusG | 734454 | c.201A>G | synonymous_variant | 0.97 | rifampicin | |
nusG | 734460 | c.207G>C | synonymous_variant | 0.97 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.97 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
nusG | 734478 | c.225C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
nusG | 734502 | c.249G>A | synonymous_variant | 0.95 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.93 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.92 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.87 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734826 | c.573A>C | synonymous_variant | 0.9 | rifampicin | |
nusG | 734841 | c.588G>C | synonymous_variant | 0.95 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.95 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.96 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734862 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734863 | p.Thr204Ser | missense_variant | 1.0 | rifampicin | |
nusG | 734886 | c.633A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 760104 | c.298_300delTCGinsAGC | synonymous_variant | 0.88 | rifampicin | |
rpoB | 760112 | c.306T>G | synonymous_variant | 0.88 | rifampicin | |
rpoB | 760115 | c.309C>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 760127 | c.321C>T | synonymous_variant | 0.9 | rifampicin | |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.91 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760274 | c.468G>A | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760454 | c.648C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760478 | c.672C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760502 | c.696C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.94 | rifampicin | |
rpoB | 760595 | c.789C>T | synonymous_variant | 0.95 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760649 | c.843G>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760721 | c.915C>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 760796 | c.990A>G | synonymous_variant | 0.8 | rifampicin | |
rpoB | 760800 | p.Val332Ile | missense_variant | 0.83 | rifampicin | Uncertain significance |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.86 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.87 | rifampicin | |
rpoB | 760829 | c.1023C>T | synonymous_variant | 0.9 | rifampicin | |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760858 | p.Val351Ala | missense_variant | 0.93 | rifampicin | Uncertain significance |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 760887 | p.Thr361Val | missense_variant | 0.93 | rifampicin | Uncertain significance |
rpoB | 760919 | c.1113C>T | synonymous_variant | 0.93 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.91 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 760965 | p.Met387Leu | missense_variant | 0.91 | rifampicin | Uncertain significance |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 760973 | c.1167G>T | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>T | synonymous_variant | 0.91 | rifampicin | |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.81 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>A | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761066 | c.1260G>C | synonymous_variant | 0.77 | rifampicin | |
rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761147 | c.1341C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761171 | c.1365C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761234 | c.1428G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761273 | c.1467T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761318 | c.1512G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761345 | c.1539G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761346 | p.Val514Ile | missense_variant | 1.0 | rifampicin | |
rpoB | 761355 | p.Val517Lys | missense_variant | 1.0 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
rpoB | 761367 | p.Glu521Gln | missense_variant | 1.0 | rifampicin | |
rpoB | 761374 | p.Val523Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 761381 | c.1575G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761561 | c.1755C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761564 | c.1758G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761669 | c.1863C>T | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761687 | c.1881C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761693 | c.1887G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.95 | rifampicin | |
rpoB | 761789 | c.1983G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761791 | p.Arg662Gln | missense_variant | 0.95 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761819 | c.2013G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761990 | c.2184G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 762002 | c.2196C>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 762003 | c.2197_2199delAACinsCG | frameshift_variant&missense_variant | 0.93 | rifampicin | |
rpoB | 762014 | c.2208C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 762026 | c.2220G>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 762029 | c.2223C>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 762032 | c.2226C>G | synonymous_variant | 0.91 | rifampicin | |
rpoB | 762035 | c.2229G>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762137 | c.2331C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 762156 | c.2350_2352delGTGinsAC | frameshift_variant&missense_variant | 0.96 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762212 | c.2406G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762239 | c.2433G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762245 | c.2439G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762290 | c.2484C>T | synonymous_variant | 0.97 | rifampicin | |
rpoB | 762293 | c.2487T>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 762299 | c.2493G>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 762308 | c.2502G>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 762314 | c.2508C>T | synonymous_variant | 0.96 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762833 | c.3027C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762839 | c.-531G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762863 | c.-507T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762879 | p.Met1025Leu | missense_variant | 0.98 | rifampicin | Uncertain significance |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 762959 | c.3153G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.92 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 763053 | c.3247_3249delTTGinsCC | frameshift_variant&missense_variant | 0.95 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>G | upstream_gene_variant | 0.96 | rifampicin | |
rpoC | 763079 | c.-291C>G | upstream_gene_variant | 0.95 | rifampicin | |
rpoC | 763100 | c.-270G>A | upstream_gene_variant | 0.96 | rifampicin | |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 763130 | c.3324G>A | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763133 | c.-237G>C | upstream_gene_variant | 0.98 | rifampicin | |
rpoC | 763160 | c.-210G>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.96 | rifampicin | |
rpoC | 763181 | c.-189G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763375 | c.6C>A | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763414 | c.45T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763423 | p.Glu18Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 763430 | c.61_63delAGGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763433 | c.64_66delCAAinsAC | frameshift_variant&missense_variant | 0.93 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763558 | c.189C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763615 | c.246G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763762 | c.393C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 763781 | c.412_414delTCGinsAGC | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763903 | c.534G>A | synonymous_variant | 0.92 | rifampicin | |
rpoC | 763906 | c.537C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 763919 | c.550C>T | synonymous_variant | 0.94 | rifampicin | |
rpoC | 763930 | c.561G>A | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763933 | c.564C>A | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763940 | p.Ala191Ser | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763947 | p.Ala193Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 763951 | c.582G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763960 | c.591T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763987 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764040 | p.Ser224Thr | missense_variant | 1.0 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764060 | p.Pro231Val | missense_variant | 1.0 | rifampicin | |
rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764077 | c.708C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764169 | p.Asn267Thr | missense_variant | 0.98 | rifampicin | |
rpoC | 764179 | c.810C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764182 | p.Asp271Glu | missense_variant | 0.97 | rifampicin | Uncertain significance |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764191 | c.822C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764207 | p.Val280Thr | missense_variant | 0.94 | rifampicin | Uncertain significance |
rpoC | 764213 | p.Arg282Lys | missense_variant | 0.94 | rifampicin | Uncertain significance |
rpoC | 764227 | c.858G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764254 | c.885G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764263 | c.894G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764274 | c.908_909insGACCA | frameshift_variant | 0.95 | rifampicin | |
rpoC | 764280 | c.911_916delAGTCGGinsC | frameshift_variant&missense_variant | 0.95 | rifampicin | |
rpoC | 764296 | c.927G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764312 | p.Asp315Asn | missense_variant | 0.97 | rifampicin | |
rpoC | 764344 | c.975C>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764371 | c.1002G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764405 | c.1036_1038delAGGinsCT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764485 | c.1116G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764491 | c.1122G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764530 | c.1161C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764605 | c.1236G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764665 | c.1296C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764701 | c.1332C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764713 | c.1344G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764746 | c.1377G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764758 | c.1389C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764844 | p.Ala492Gly | missense_variant | 0.98 | rifampicin | |
rpoC | 764854 | c.1485G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764863 | c.1494G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764869 | c.1500C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764878 | c.1509C>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764887 | c.1518G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 0.95 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 764920 | c.1551G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764953 | c.1584G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764956 | c.1587T>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 764971 | c.1602C>G | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.9 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 765085 | c.1716T>G | synonymous_variant | 0.91 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 765100 | c.1731G>C | synonymous_variant | 0.91 | rifampicin | |
rpoC | 765103 | c.1734G>T | synonymous_variant | 0.9 | rifampicin | |
rpoC | 765394 | c.2025G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
rpoC | 765407 | c.2038_2040delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765422 | p.Asn685Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 765454 | c.2085C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765466 | c.2097C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765484 | c.2115G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765493 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765544 | c.2175C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765547 | c.2178C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoC | 765861 | p.Phe831Tyr | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoC | 765874 | c.2505G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 765875 | p.Val836Ile | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765904 | c.2535C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765908 | c.2539C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765934 | c.2565C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765937 | c.2568T>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765940 | c.2571A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765946 | c.2577C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765947 | c.2578T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765952 | c.2583G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765962 | c.2593T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 766270 | c.2901G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 1.0 | rifampicin | |
rpoC | 766291 | c.2922G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766297 | c.2928G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766309 | c.2940G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766315 | c.2946C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 766434 | p.Glu1022Gly | missense_variant | 0.94 | rifampicin | |
rpoC | 766459 | c.3090G>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766783 | c.3414C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 766846 | c.3477C>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 766931 | c.3562_3564delGCAinsTG | frameshift_variant&stop_gained | 0.8 | rifampicin | |
rpoC | 766942 | c.3573C>T | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 766945 | c.3576A>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 766954 | c.3585C>G | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766961 | p.Gly1198Asn | missense_variant | 0.89 | rifampicin | |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 767020 | c.3651C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767023 | c.3654C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767106 | p.Asn1246Met | missense_variant | 0.97 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 767162 | p.Asn1265Ala | missense_variant | 0.98 | rifampicin | |
rpoC | 767174 | p.Asn1269Asp | missense_variant | 0.98 | rifampicin | |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.98 | rifampicin | |
rpoC | 767197 | c.3828G>A | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767269 | c.3900C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767296 | c.3927C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775847 | c.2634G>C | synonymous_variant | 0.9 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.86 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775862 | c.2619G>C | synonymous_variant | 0.86 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775865 | c.2616T>C | synonymous_variant | 0.87 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775885 | p.Ile866Leu | missense_variant | 0.91 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775886 | c.2595A>G | synonymous_variant | 0.88 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775895 | c.2586C>A | synonymous_variant | 0.95 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.95 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775910 | c.2571G>T | synonymous_variant | 0.93 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775915 | p.Ala856Ser | missense_variant | 0.65 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.94 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775919 | c.2562G>C | synonymous_variant | 0.65 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.32 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775940 | c.2541C>T | synonymous_variant | 0.96 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.56 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775946 | c.2535C>G | synonymous_variant | 0.56 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.59 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775972 | p.Ala837Pro | missense_variant | 0.61 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.72 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.95 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775991 | c.2488_2490delGAGinsAC | frameshift_variant&missense_variant | 0.54 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.91 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776003 | c.2478C>T | synonymous_variant | 0.64 | clofazimine | |
bedaquiline | ||||||
rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.95 | streptomycin | |
rpsL | 781598 | c.39G>C | synonymous_variant | 0.95 | streptomycin | |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.96 | streptomycin | |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781652 | c.93T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781766 | c.207C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
rpsL | 781817 | c.258G>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781829 | c.270G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781898 | c.339A>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781916 | c.357T>G | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.95 | streptomycin | Uncertain significance |
rplC | 800498 | c.-311G>A | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800531 | c.-278T>C | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.93 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800570 | c.-239C>G | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800574 | c.-235_-234delGTinsAC | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800585 | c.-224T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800594 | c.-215C>G | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800597 | c.-212A>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800600 | c.-209G>A | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800633 | c.-176T>C | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800645 | c.-164C>G | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800678 | c.-131C>T | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800693 | c.-116A>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800702 | c.-107G>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800744 | c.-65G>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800745 | c.-64_-62delCTCinsTG | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800759 | c.-50C>T | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800762 | c.-47T>G | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800780 | c.-29C>G | upstream_gene_variant | 0.9 | linezolid | |
fbiC | 1303525 | p.Ser199Ala | missense_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303581 | c.651G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303788 | c.858T>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303794 | c.864A>G | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303827 | c.897A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Thr | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303869 | c.939T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303871 | p.Tyr314Phe | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303878 | c.948G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304547 | c.1617C>G | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304567 | p.Phe546Tyr | missense_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304628 | c.1698G>C | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304637 | c.1707G>A | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304760 | c.1830G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304796 | c.1866G>A | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304799 | c.1869G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304802 | c.1872G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304805 | c.1875G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304809 | p.Ser627Gly | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
atpE | 1461179 | c.135G>C | synonymous_variant | 0.91 | bedaquiline | |
atpE | 1461182 | c.138A>G | synonymous_variant | 0.91 | bedaquiline | |
atpE | 1461185 | c.141G>C | synonymous_variant | 0.91 | bedaquiline | |
atpE | 1461188 | c.144G>T | synonymous_variant | 0.91 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.91 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.9 | bedaquiline | |
rrs | 1471514 | n.-332A>C | upstream_gene_variant | 0.96 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471517 | n.-329T>C | upstream_gene_variant | 0.96 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471541 | n.-305G>C | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471547 | n.-299C>G | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471550 | n.-296T>C | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471553 | n.-293C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471562 | n.-284A>G | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471931 | n.87delA | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471936 | n.91A>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472032 | n.187G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472035 | n.190G>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472041 | n.196C>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472042 | n.197T>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.95 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472289 | n.444T>C | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472297 | n.453_465delGTCCGGGTTCTCT | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472312 | n.467_468insC | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472337 | n.492C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472380 | n.535G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472846 | n.1001C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472848 | n.1003T>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472860 | n.1015C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472861 | n.1016G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTC | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473696 | n.39T>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473697 | n.40C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473743 | n.86C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473754 | n.97G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473757 | n.100T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474266 | n.609T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474284 | n.629dupC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474292 | n.635_644delTTCCTCTCCGinsC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474303 | n.646A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474306 | n.649A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.653_654delTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474374 | n.717T>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474672 | n.1015C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474709 | n.1053delT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474715 | n.1061delA | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475200 | n.1543T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475202 | n.1545G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475221 | n.1564C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475232 | n.1575A>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475425 | n.1768G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475429 | n.1772G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475430 | n.1773T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475480 | n.1823A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475482 | n.1825A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475603 | n.1946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475607 | n.1950A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475759 | n.2102_2106delCCCGCinsTCGT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475989 | n.2332T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1476034 | n.2377C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>A | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476056 | n.2399G>A | non_coding_transcript_exon_variant | 0.92 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476088 | n.2431A>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476666 | n.3009C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1476692 | n.3035T>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476741 | n.3084G>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1476743 | n.3086A>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476744 | n.3087G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476746 | n.3089T>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476755 | n.3098G>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476757 | n.3101delG | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
inhA | 1673646 | c.-556T>C | upstream_gene_variant | 0.9 | ethionamide | |
isoniazid | ||||||
inhA | 1673652 | c.-550C>G | upstream_gene_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1673658 | c.-544G>C | upstream_gene_variant | 0.92 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673660 | p.Ala74Glu | missense_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1673670 | c.-532G>A | upstream_gene_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.92 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1674522 | c.321G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674534 | c.333G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674550 | p.Ser117Ala | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674600 | c.399G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674601 | p.Leu134Val | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674621 | c.420C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674628 | p.Ser143Gly | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674639 | c.438C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674663 | c.462G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674669 | c.468G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517_519delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674726 | c.525G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674729 | c.528G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674732 | c.531C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674745 | p.Tyr182Val | missense_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1674756 | c.555T>G | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
inhA | 1674774 | c.573A>C | synonymous_variant | 0.86 | ethionamide | |
isoniazid | ||||||
inhA | 1674777 | c.576C>G | synonymous_variant | 0.83 | ethionamide | |
isoniazid | ||||||
inhA | 1674780 | c.579T>C | synonymous_variant | 0.87 | ethionamide | |
isoniazid | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
inhA | 1674810 | c.609C>G | synonymous_variant | 0.86 | ethionamide | |
isoniazid | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 0.86 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674819 | c.618G>C | synonymous_variant | 0.86 | ethionamide | |
isoniazid | ||||||
inhA | 1674822 | c.621C>G | synonymous_variant | 0.85 | ethionamide | |
isoniazid | ||||||
inhA | 1674825 | c.624C>T | synonymous_variant | 0.89 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674827 | p.Glu209Ala | missense_variant | 0.89 | ethionamide | |
isoniazid | ||||||
inhA | 1674839 | p.Ala213Asp | missense_variant | 0.89 | ethionamide | |
isoniazid | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.9 | ethionamide | |
isoniazid | ||||||
inhA | 1674847 | p.Gln216Lys | missense_variant | 0.9 | ethionamide | |
isoniazid | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674909 | c.708G>A | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674915 | c.714C>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674924 | c.723G>C | synonymous_variant | 0.97 | ethionamide | |
isoniazid | ||||||
inhA | 1674933 | c.732G>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674937 | p.Leu246Met | missense_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674954 | c.753G>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674957 | c.756G>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
inhA | 1674963 | c.762G>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
inhA | 1674966 | c.765T>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
inhA | 1674967 | p.Asp256Ser | missense_variant | 0.93 | ethionamide | |
isoniazid | ||||||
rpsA | 1833616 | c.75A>C | synonymous_variant | 0.93 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1833625 | c.84A>G | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1833628 | c.87G>C | synonymous_variant | 0.95 | pyrazinamide | |
rpsA | 1833634 | c.93G>A | synonymous_variant | 0.95 | pyrazinamide | |
rpsA | 1833664 | c.123C>G | synonymous_variant | 0.93 | pyrazinamide | |
rpsA | 1833676 | c.135A>G | synonymous_variant | 0.92 | pyrazinamide | |
rpsA | 1833679 | c.138G>T | synonymous_variant | 0.92 | pyrazinamide | |
rpsA | 1833685 | c.144G>T | synonymous_variant | 0.92 | pyrazinamide | |
rpsA | 1833691 | c.150G>A | synonymous_variant | 0.92 | pyrazinamide | |
rpsA | 1833694 | c.153G>C | synonymous_variant | 0.91 | pyrazinamide | |
rpsA | 1833695 | c.154_156delCTCinsTG | frameshift_variant&missense_variant | 0.91 | pyrazinamide | Uncertain significance |
rpsA | 1833724 | c.183C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833730 | c.189C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833733 | c.192C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833734 | p.Ala65Ser | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1833745 | c.204G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833772 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833778 | c.237C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833781 | c.240T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833820 | c.279G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833862 | c.321G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833865 | c.324G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833894 | p.Ala118Glu | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834012 | c.471G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834192 | c.651C>G | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834213 | c.672G>C | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834219 | c.678C>G | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.96 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.96 | pyrazinamide | |
rpsA | 1834252 | c.711C>T | synonymous_variant | 0.96 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834294 | c.753G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834361 | c.820T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834387 | c.846C>T | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834408 | c.867C>T | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834456 | c.915T>G | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834462 | c.921C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834477 | c.936C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834483 | c.942G>A | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834522 | c.981C>T | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834552 | c.1011G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834600 | c.1059G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834606 | c.1065C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834667 | p.Ala376Ser | missense_variant | 0.97 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834723 | c.1182G>A | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834759 | c.1218A>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Asn | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834810 | c.1269C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834813 | c.1272G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834828 | c.1287C>T | synonymous_variant | 1.0 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.95 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.94 | linezolid | |
tsnR | 1853384 | c.-222G>T | upstream_gene_variant | 0.92 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.9 | linezolid | |
tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 0.9 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.9 | linezolid | |
katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.98 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2517992 | c.-123C>T | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.9 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.93 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.94 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.94 | isoniazid | |
kasA | 2518688 | p.Val192Phe | missense_variant | 0.94 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.94 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518715 | p.Pro201Gly | missense_variant | 0.94 | isoniazid | |
kasA | 2518726 | c.612G>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518756 | c.642G>C | synonymous_variant | 1.0 | isoniazid | |
Rv2477c | 2782451 | p.Ala531Gly | missense_variant | 0.93 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.96 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782495 | p.Asp516Glu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782510 | c.1533G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782555 | c.1488G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782558 | c.1485T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.93 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>T | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783014 | p.Ser343Thr | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783344 | c.699C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.96 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783377 | c.666C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783380 | c.663C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783410 | c.633G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.89 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783626 | c.415_417delGCGinsTC | frameshift_variant&missense_variant | 0.9 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783634 | p.Leu137Ile | missense_variant | 0.93 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783641 | c.402G>C | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783651 | p.His131Ala | missense_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783668 | c.375G>C | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783672 | p.Arg124Gln | missense_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783689 | c.354G>C | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.94 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
pepQ | 2859798 | c.621G>C | synonymous_variant | 0.92 | clofazimine | |
bedaquiline | ||||||
pepQ | 2859822 | c.597T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
Rv2752c | 3065721 | c.471G>C | synonymous_variant | 0.92 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065732 | c.460T>C | synonymous_variant | 0.89 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065742 | p.Thr150Ile | missense_variant | 0.9 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065748 | c.444T>C | synonymous_variant | 0.9 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065769 | c.423C>T | synonymous_variant | 0.89 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065775 | c.417T>C | synonymous_variant | 0.89 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065781 | c.411C>A | synonymous_variant | 0.88 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065789 | c.403C>A | synonymous_variant | 0.88 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065791 | p.Thr134Ser | missense_variant | 0.88 | ethambutol | Uncertain significance |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065799 | c.393C>G | synonymous_variant | 0.93 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065806 | p.Arg129Ala | missense_variant | 0.91 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065808 | c.384C>G | synonymous_variant | 0.91 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066006 | c.186G>C | synonymous_variant | 0.8 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066027 | c.165C>G | synonymous_variant | 0.87 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066030 | c.162G>A | synonymous_variant | 0.88 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3066042 | c.150T>G | synonymous_variant | 0.87 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066045 | c.147T>C | synonymous_variant | 0.91 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066051 | c.141G>C | synonymous_variant | 0.92 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066054 | c.138T>G | synonymous_variant | 0.88 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066066 | c.124_126delATTinsGC | frameshift_variant&missense_variant | 0.91 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3066071 | c.121T>C | synonymous_variant | 0.91 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.87 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066087 | c.105A>G | synonymous_variant | 0.87 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
thyX | 3067337 | c.609C>T | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
thyX | 3067340 | c.606G>A | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
thyX | 3067343 | c.603C>T | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>G | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
thyX | 3067406 | c.540A>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
thyX | 3067421 | c.525G>T | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
thyX | 3067430 | c.516C>G | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067433 | c.513C>T | synonymous_variant | 0.87 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.87 | para-aminosalicylic_acid | |
thyX | 3067442 | c.504C>G | synonymous_variant | 0.86 | para-aminosalicylic_acid | |
mtrB | 3625135 | c.1479A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625149 | p.Val489Ile | missense_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625162 | c.-252T>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625168 | c.-258G>T | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625177 | c.-267C>G | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625192 | c.-282G>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625195 | c.-285A>C | upstream_gene_variant | 1.0 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.81 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.86 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.87 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625741 | c.-831G>A | upstream_gene_variant | 0.88 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625747 | c.867G>C | synonymous_variant | 0.91 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.87 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.95 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.95 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625766 | c.-857_-856delTCinsAG | upstream_gene_variant | 0.95 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625795 | c.-885G>C | upstream_gene_variant | 0.96 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625801 | c.-891G>C | upstream_gene_variant | 0.95 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.94 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.94 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.94 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.94 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625845 | p.Ser257Thr | missense_variant | 0.94 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.88 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.88 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625855 | c.759G>A | synonymous_variant | 0.88 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625858 | c.-948C>G | upstream_gene_variant | 0.88 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625864 | c.750T>C | synonymous_variant | 0.88 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625879 | c.735G>A | synonymous_variant | 0.92 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625882 | c.-972G>C | upstream_gene_variant | 0.9 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625888 | c.726G>A | synonymous_variant | 0.9 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625899 | p.Val239Leu | missense_variant | 0.91 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.92 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626735 | c.-122C>T | upstream_gene_variant | 0.93 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626750 | c.-137T>G | upstream_gene_variant | 0.94 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.95 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626768 | c.582G>C | synonymous_variant | 0.89 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.85 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.85 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.85 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.86 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626792 | c.-179G>C | upstream_gene_variant | 0.93 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 0.93 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.94 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626825 | c.-212T>G | upstream_gene_variant | 0.94 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626840 | c.-227C>T | upstream_gene_variant | 0.92 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.9 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
rpoA | 3877638 | c.870T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoA | 3877647 | c.861C>T | synonymous_variant | 0.94 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoA | 3877662 | c.846C>T | synonymous_variant | 0.95 | rifampicin | |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.95 | rifampicin | |
rpoA | 3877671 | c.837C>G | synonymous_variant | 0.95 | rifampicin | |
rpoA | 3877677 | c.831G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoA | 3877728 | c.780C>G | synonymous_variant | 0.96 | rifampicin | |
rpoA | 3877740 | c.768G>C | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3877749 | c.759C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3877758 | c.750G>C | synonymous_variant | 0.99 | rifampicin | |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoA | 3877794 | c.714G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3877821 | c.687C>G | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877865 | c.643C>T | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877878 | c.630G>A | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877881 | c.627G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877887 | c.621G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877893 | c.615C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | c.600T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3877920 | c.588G>A | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3877971 | p.Asp179Glu | missense_variant | 0.97 | rifampicin | Uncertain significance |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.95 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoA | 3877995 | c.513G>C | synonymous_variant | 0.94 | rifampicin | |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoA | 3878082 | c.426T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878127 | c.381G>C | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.98 | rifampicin | Uncertain significance |
rpoA | 3878145 | c.363C>G | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.98 | rifampicin | |
rpoA | 3878184 | c.324C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoA | 3878196 | p.Glu104Ala | missense_variant | 0.97 | rifampicin | Uncertain significance |
rpoA | 3878202 | c.306G>C | synonymous_variant | 0.97 | rifampicin | |
rpoA | 3878205 | c.303T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoA | 3878264 | p.Ser82Gly | missense_variant | 0.95 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.95 | rifampicin | Uncertain significance |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoA | 3878310 | c.198G>C | synonymous_variant | 0.85 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoA | 3878328 | c.180G>C | synonymous_variant | 0.83 | rifampicin | |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.85 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.88 | rifampicin | |
rpoA | 3878872 | c.-365G>C | upstream_gene_variant | 0.91 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.92 | rifampicin | Uncertain significance |
rpoA | 3878886 | c.-379G>A | upstream_gene_variant | 0.96 | rifampicin | Uncertain significance |
rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 0.96 | rifampicin | |
rpoA | 3878893 | c.-388_-386delCACinsAG | upstream_gene_variant | 0.96 | rifampicin | |
rpoA | 3878899 | c.-392C>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 0.97 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.97 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>C | upstream_gene_variant | 0.97 | rifampicin | |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878947 | c.-440G>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878962 | c.-455G>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879121 | c.-616_-614delCTTinsAAC | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879124 | c.-618_-617delTGinsGC | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 0.67 | rifampicin | |
rpoA | 3879151 | c.-644C>G | upstream_gene_variant | 0.73 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.73 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.8 | rifampicin | |
ddn | 3986622 | c.-222C>T | upstream_gene_variant | 0.94 | delamanid | |
pretomanid | ||||||
ddn | 3986631 | c.-213A>T | upstream_gene_variant | 0.92 | delamanid | |
pretomanid | ||||||
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.92 | delamanid | |
pretomanid | ||||||
ddn | 3986646 | c.-198_-196delCTCinsTG | upstream_gene_variant | 0.92 | delamanid | |
pretomanid | ||||||
ddn | 3986656 | c.-188C>G | upstream_gene_variant | 0.96 | delamanid | |
pretomanid | ||||||
ddn | 3986661 | c.-183C>A | upstream_gene_variant | 0.96 | delamanid | |
pretomanid | ||||||
ddn | 3986665 | c.-179G>C | upstream_gene_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3986696 | c.-148G>T | upstream_gene_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3986699 | c.-145C>T | upstream_gene_variant | 1.0 | delamanid | |
pretomanid | ||||||
ddn | 3986702 | c.-142G>C | upstream_gene_variant | 1.0 | delamanid | |
pretomanid | ||||||
clpC1 | 4038308 | p.Val799Asn | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038317 | c.2388G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038329 | p.Glu792Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038383 | c.2322G>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038395 | c.2310C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038416 | c.2289C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038512 | c.2193C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038519 | p.Arg729Ala | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038533 | p.Arg724Gln | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038587 | c.2118C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038620 | p.Gln695Leu | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038657 | p.Lys683Ser | missense_variant | 0.92 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038668 | c.2037G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038674 | c.2031C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038679 | p.Pro676Ala | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038767 | c.1938G>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038779 | c.1926C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038795 | p.Ser637Thr | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038881 | c.1824C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038902 | c.1803C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038905 | c.1800A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038911 | c.1794G>T | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.98 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039034 | c.1671C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039067 | c.1638G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039073 | c.1632C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039079 | c.1626C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039091 | c.1614G>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>T | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039133 | c.1572C>G | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039139 | c.1566G>A | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>T | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.98 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.98 | pyrazinamide | |
clpC1 | 4039181 | c.1522_1524delTTGinsCC | frameshift_variant&missense_variant | 0.98 | pyrazinamide | |
clpC1 | 4039187 | c.1518G>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039199 | p.Ala502Glu | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039217 | c.1488G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039265 | c.1440C>T | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039283 | c.1422C>T | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039292 | c.1413C>T | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.84 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039310 | c.1395A>G | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>G | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.83 | pyrazinamide | |
clpC1 | 4039346 | c.1359G>T | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039355 | c.1350G>C | synonymous_variant | 0.9 | pyrazinamide | |
clpC1 | 4039359 | p.Ser449Asn | missense_variant | 0.9 | pyrazinamide | |
clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.91 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>C | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>C | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.95 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>T | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039472 | c.1233G>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.97 | pyrazinamide | |
clpC1 | 4039544 | c.1161C>T | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4039601 | c.1104G>A | synonymous_variant | 0.89 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039635 | p.Glu357Leu | missense_variant | 0.88 | pyrazinamide | |
clpC1 | 4039649 | c.1056G>C | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4039688 | c.1017G>A | synonymous_variant | 0.76 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039733 | c.972G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039766 | c.939T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.98 | pyrazinamide | |
clpC1 | 4039802 | c.903G>C | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4039805 | c.900C>G | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4039814 | c.891C>G | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039820 | c.885T>A | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039829 | c.874_876delTTGinsCC | frameshift_variant&missense_variant | 0.93 | pyrazinamide | |
clpC1 | 4039832 | c.873C>G | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4039840 | c.865C>T | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039913 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039925 | c.780C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039943 | c.762G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039946 | c.759A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039949 | c.756G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039994 | p.Glu237Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4040015 | c.690G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040021 | c.684A>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040027 | c.678C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040030 | c.675C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040057 | c.648C>T | synonymous_variant | 0.98 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040108 | c.597G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040126 | c.579C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040141 | c.564C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040144 | c.561G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040159 | c.546G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040168 | c.537G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040195 | c.510G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040200 | c.505T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040201 | c.504C>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040207 | c.498T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040214 | p.Ser164Asn | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4040219 | c.484_486delTCCinsGG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040228 | c.477G>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040257 | p.Ala150Thr | missense_variant | 0.95 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4040309 | c.396C>G | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040321 | c.384C>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040345 | c.360C>T | synonymous_variant | 0.96 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.95 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.94 | pyrazinamide | |
clpC1 | 4040369 | c.334_336delCTCinsTG | frameshift_variant&synonymous_variant | 0.91 | pyrazinamide | |
clpC1 | 4040393 | c.312G>T | synonymous_variant | 0.9 | pyrazinamide | |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040477 | c.228G>T | synonymous_variant | 0.91 | pyrazinamide | |
clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040636 | c.69C>G | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4040648 | c.57G>A | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4040654 | c.51G>A | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4040674 | c.31A>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040675 | c.30C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040690 | c.15T>C | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4040695 | c.10C>A | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4040696 | c.9A>G | synonymous_variant | 0.93 | pyrazinamide | |
clpC1 | 4040706 | c.-2C>G | upstream_gene_variant | 0.93 | pyrazinamide | |
clpC1 | 4040710 | c.-6C>A | upstream_gene_variant | 0.92 | pyrazinamide | |
clpC1 | 4040711 | c.-7G>A | upstream_gene_variant | 0.92 | pyrazinamide | |
glpK | 4138457 | p.Asp433Glu | missense_variant | 0.8 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138464 | p.Gly431Ala | missense_variant | 0.88 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138472 | c.1284G>C | synonymous_variant | 0.95 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138478 | c.1278T>C | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138481 | c.1275G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138489 | c.1267T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138495 | p.Gln421Glu | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138500 | p.Arg419His | missense_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138502 | c.1254T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138505 | c.1251T>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138511 | c.1245C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138514 | c.1242A>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138535 | c.1221T>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138541 | c.1215C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138567 | p.Thr397Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138568 | c.1188A>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138571 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138580 | c.1176C>T | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138583 | c.1173G>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138601 | c.1155G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138610 | c.1146C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138616 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138622 | c.1134C>G | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138625 | c.1131G>C | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139621 | c.135G>A | synonymous_variant | 1.0 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | ||||||
embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4240729 | c.867C>G | synonymous_variant | 0.93 | ethambutol | |
embC | 4240736 | p.Ser292Ala | missense_variant | 0.95 | ethambutol | |
embC | 4240756 | c.894G>C | synonymous_variant | 0.95 | ethambutol | |
embC | 4240774 | c.912C>G | synonymous_variant | 0.95 | ethambutol | |
embC | 4240778 | c.916_918delCATinsAC | frameshift_variant&missense_variant | 0.95 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.95 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.95 | ethambutol | |
embC | 4240790 | p.Met310Leu | missense_variant | 0.95 | ethambutol | |
embC | 4240807 | c.945C>G | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
embC | 4240816 | c.954C>T | synonymous_variant | 0.92 | ethambutol | |
embC | 4240819 | c.957A>C | synonymous_variant | 0.9 | ethambutol | |
embC | 4240822 | c.960C>G | synonymous_variant | 0.9 | ethambutol | |
embC | 4240954 | c.1092T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240960 | c.1098G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240963 | c.1101G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241008 | c.1146G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241026 | c.1164C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
embC | 4241047 | c.1185C>G | synonymous_variant | 0.96 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.96 | ethambutol | |
embC | 4241059 | c.1197G>A | synonymous_variant | 0.97 | ethambutol | |
embC | 4241063 | c.1201_1203delATCinsCG | frameshift_variant&missense_variant | 0.97 | ethambutol | |
embC | 4241071 | c.1209C>G | synonymous_variant | 0.97 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.97 | ethambutol | |
embC | 4241104 | c.1242G>A | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.96 | ethambutol | |
embC | 4241131 | c.1269G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241412 | p.Ile517Thr | missense_variant | 1.0 | ethambutol | |
embC | 4241439 | p.Ser526Thr | missense_variant | 0.95 | ethambutol | |
embC | 4241443 | c.1581C>G | synonymous_variant | 0.95 | ethambutol | |
embC | 4241452 | c.1590G>C | synonymous_variant | 0.95 | ethambutol | |
embC | 4241464 | c.1602C>G | synonymous_variant | 0.95 | ethambutol | |
embC | 4241470 | c.1608C>G | synonymous_variant | 0.94 | ethambutol | |
embC | 4241480 | p.Leu540Val | missense_variant | 1.0 | ethambutol | |
embC | 4241483 | p.Val541Leu | missense_variant | 1.0 | ethambutol | |
embC | 4241494 | c.1632C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244669 | c.1437G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244678 | c.1446G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4244681 | c.1449A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embA | 4244684 | c.1452C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244694 | p.Lys488Val | missense_variant | 1.0 | ethambutol | |
embA | 4244699 | c.1467C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4244723 | c.1491G>A | synonymous_variant | 1.0 | ethambutol | |
embA | 4245243 | p.Ala671Ser | missense_variant | 0.8 | ethambutol | |
embA | 4245248 | c.2016G>C | synonymous_variant | 0.73 | ethambutol | |
embA | 4245257 | c.2025A>G | synonymous_variant | 0.67 | ethambutol | |
embA | 4245263 | c.2031A>G | synonymous_variant | 0.67 | ethambutol | Not assoc w R - Interim |
embA | 4245264 | p.Asp678Asn | missense_variant | 0.67 | ethambutol | Uncertain significance |
embA | 4245270 | p.Arg680Lys | missense_variant | 0.67 | ethambutol | |
embA | 4245281 | c.2049C>G | synonymous_variant | 0.8 | ethambutol | |
embA | 4245282 | c.2050_2052delATCinsGG | frameshift_variant&missense_variant | 0.8 | ethambutol | Uncertain significance |
embA | 4245290 | c.2058C>G | synonymous_variant | 0.8 | ethambutol | |
embA | 4245293 | c.2061T>C | synonymous_variant | 0.8 | ethambutol | Not assoc w R - Interim |
embB | 4247426 | p.Gly305Gln | missense_variant | 0.91 | ethambutol | |