TB-Profiler result

Run: ERR108471
Summary

Run ID: ERR108471

Sample name:

Date: 2024-04-15T23:30:53.725090

Number of reads: 329782

Percentage reads mapped: 7.18

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.508_510delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.601_603delATGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491290 c.508_510delGTGinsAC frameshift_variant&missense_variant 0.92 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303531 c.601_603delATGinsCC frameshift_variant&missense_variant 0.93 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155693 p.Ser140Asn missense_variant 1.0 isoniazid Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 558 c.558G>C synonymous_variant 1.0 isoniazid
dnaA 570 c.570C>G synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 594 c.594C>G synonymous_variant 1.0 isoniazid
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 627 c.627G>A synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>G synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 660 c.660G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>T synonymous_variant 1.0 isoniazid
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 687 c.687C>T synonymous_variant 0.94 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.96 isoniazid
dnaA 702 c.702C>T synonymous_variant 0.96 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.96 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.96 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.97 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.97 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.97 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.97 isoniazid
dnaA 783 c.783C>T synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 798 c.798C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 888 c.888C>G synonymous_variant 1.0 isoniazid
dnaA 894 c.894G>A synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 903 c.903C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 1.0 isoniazid
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 933 c.933C>G synonymous_variant 1.0 isoniazid
gyrB 5812 c.573C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 5818 c.579G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 5839 c.600C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5863 c.624G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5865 p.Thr209Ser missense_variant 0.94 levofloxacin
moxifloxacin
gyrB 5869 c.630C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5882 p.Gln215Ala missense_variant 0.94 levofloxacin
moxifloxacin
gyrB 5893 c.654C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6187 c.948C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6208 c.969G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 6215 p.Ser326Thr missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6323 c.1085_1086insGTCT frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6327 c.1090_1093delGAAC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6334 c.-968G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6658 c.-644G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6721 c.1482C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6724 c.-578G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 p.Ile519Leu missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6798 p.Gly520Ala missense_variant 0.96 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6800 p.Lys521Arg missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.96 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7355 c.54T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7778 c.477G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7796 c.495G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7853 c.552C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7890 c.589C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8636 c.1335A>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8639 c.1338G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8849 c.1548C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.96 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9145 p.Arg615Gln missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 9147 p.Gly616Ser missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Gln missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9203 c.1902G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9213 p.Thr638Glu missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9254 c.1953C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9281 c.1980C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9299 c.1998G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9368 c.2067G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9413 c.2112G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 0.93 levofloxacin
moxifloxacin
fgd1 491259 c.477T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>T synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.68 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491320 p.Ala180Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.71 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491370 c.588C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491559 c.777G>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491605 c.823C>T synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
mshA 575659 c.312A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.96 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575714 p.Tyr123Asn missense_variant 0.96 ethionamide
isoniazid
mshA 575728 c.381C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575804 c.457_459delTCGinsAGC synonymous_variant 1.0 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575818 c.471G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.94 ethionamide
isoniazid
ccsA 620569 c.679_681delGGAinsCG frameshift_variant&missense_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>T synonymous_variant 0.92 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620607 c.717T>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620658 c.768C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620679 c.789C>G synonymous_variant 0.92 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620698 p.Val270Ile missense_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.7 capreomycin
amikacin
kanamycin
hadA 731729 c.-201C>T upstream_gene_variant 0.83 isoniazid
hadA 731732 c.-198G>C upstream_gene_variant 0.85 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.91 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.94 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.94 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.94 isoniazid
hadA 731813 c.-117C>T upstream_gene_variant 0.94 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.95 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 731860 c.-70C>G upstream_gene_variant 1.0 isoniazid
nusG 734373 c.120_121insC frameshift_variant 1.0 rifampicin
nusG 734394 c.141C>A synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.94 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.96 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.97 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.97 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.97 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.97 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.97 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 0.95 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.93 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.92 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.87 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.9 rifampicin
nusG 734841 c.588G>C synonymous_variant 0.95 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.95 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.96 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.96 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734863 p.Thr204Ser missense_variant 1.0 rifampicin
nusG 734886 c.633A>G synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.88 rifampicin
rpoB 760112 c.306T>G synonymous_variant 0.88 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.88 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760127 c.321C>T synonymous_variant 0.9 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 0.91 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.93 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.96 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 1.0 rifampicin
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760591 p.Val262Ala missense_variant 0.94 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.95 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.98 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.95 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.93 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760796 c.990A>G synonymous_variant 0.8 rifampicin
rpoB 760800 p.Val332Ile missense_variant 0.83 rifampicin Uncertain significance
rpoB 760805 c.999G>C synonymous_variant 0.88 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.86 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.87 rifampicin
rpoB 760829 c.1023C>T synonymous_variant 0.9 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.93 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.93 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.93 rifampicin Uncertain significance
rpoB 760919 c.1113C>T synonymous_variant 0.93 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.92 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.91 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.91 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.91 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 0.91 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.88 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>A synonymous_variant 0.71 rifampicin
rpoB 761066 c.1260G>C synonymous_variant 0.77 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.96 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 1.0 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761346 p.Val514Ile missense_variant 1.0 rifampicin
rpoB 761355 p.Val517Lys missense_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Asp missense_variant 1.0 rifampicin
rpoB 761381 c.1575G>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.97 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.98 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761669 c.1863C>T synonymous_variant 0.97 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.96 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761789 c.1983G>C synonymous_variant 0.95 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.95 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.95 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.93 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.93 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.93 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762026 c.2220G>C synonymous_variant 0.91 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762032 c.2226C>G synonymous_variant 0.91 rifampicin
rpoB 762035 c.2229G>C synonymous_variant 0.91 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.95 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.95 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 0.96 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 1.0 rifampicin
rpoB 762245 c.2439G>T synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.98 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762290 c.2484C>T synonymous_variant 0.97 rifampicin
rpoB 762293 c.2487T>G synonymous_variant 0.97 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 0.97 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.96 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.96 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.98 rifampicin Uncertain significance
rpoB 762929 c.3123G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.92 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763040 c.3234C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247_3249delTTGinsCC frameshift_variant&missense_variant 0.95 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.96 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 0.95 rifampicin
rpoC 763100 c.-270G>A upstream_gene_variant 0.96 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.98 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.97 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.96 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 1.0 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.96 rifampicin
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.99 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.98 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.98 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.98 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.96 rifampicin
rpoC 763762 c.393C>T synonymous_variant 0.98 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.97 rifampicin
rpoC 763781 c.412_414delTCGinsAGC synonymous_variant 0.96 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.96 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 0.92 rifampicin
rpoC 763906 c.537C>G synonymous_variant 0.92 rifampicin
rpoC 763919 c.550C>T synonymous_variant 0.94 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.95 rifampicin
rpoC 763933 c.564C>A synonymous_variant 0.95 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 0.96 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764060 p.Pro231Val missense_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764077 c.708C>G synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764169 p.Asn267Thr missense_variant 0.98 rifampicin
rpoC 764179 c.810C>T synonymous_variant 0.97 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.97 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764191 c.822C>G synonymous_variant 0.97 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.95 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Thr missense_variant 0.94 rifampicin Uncertain significance
rpoC 764213 p.Arg282Lys missense_variant 0.94 rifampicin Uncertain significance
rpoC 764227 c.858G>C synonymous_variant 0.96 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.96 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.96 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.96 rifampicin
rpoC 764274 c.908_909insGACCA frameshift_variant 0.95 rifampicin
rpoC 764280 c.911_916delAGTCGGinsC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764296 c.927G>C synonymous_variant 0.97 rifampicin
rpoC 764312 p.Asp315Asn missense_variant 0.97 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.97 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.97 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764665 c.1296C>G synonymous_variant 1.0 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 1.0 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>C synonymous_variant 1.0 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.98 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764844 p.Ala492Gly missense_variant 0.98 rifampicin
rpoC 764854 c.1485G>C synonymous_variant 0.97 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.95 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.96 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764920 c.1551G>C synonymous_variant 1.0 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>C synonymous_variant 0.95 rifampicin
rpoC 764956 c.1587T>C synonymous_variant 0.94 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764971 c.1602C>G synonymous_variant 0.93 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.9 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>G synonymous_variant 0.91 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765100 c.1731G>C synonymous_variant 0.91 rifampicin
rpoC 765103 c.1734G>T synonymous_variant 0.9 rifampicin
rpoC 765394 c.2025G>A synonymous_variant 1.0 rifampicin
rpoC 765404 p.Leu679Val missense_variant 1.0 rifampicin
rpoC 765407 c.2038_2040delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765422 p.Asn685Asp missense_variant 1.0 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765484 c.2115G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765544 c.2175C>G synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765861 p.Phe831Tyr missense_variant 0.96 rifampicin Uncertain significance
rpoC 765874 c.2505G>C synonymous_variant 0.96 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.96 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.97 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765937 c.2568T>A synonymous_variant 1.0 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.96 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 1.0 rifampicin
rpoC 766297 c.2928G>C synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.98 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.98 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.96 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.96 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.96 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766434 p.Glu1022Gly missense_variant 0.94 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 0.96 rifampicin
rpoC 766783 c.3414C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766931 c.3562_3564delGCAinsTG frameshift_variant&stop_gained 0.8 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766954 c.3585C>G synonymous_variant 0.89 rifampicin
rpoC 766961 p.Gly1198Asn missense_variant 0.89 rifampicin
rpoC 766972 c.3603G>C synonymous_variant 0.96 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Met missense_variant 0.97 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.98 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.98 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.98 rifampicin
rpoC 767197 c.3828G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>T synonymous_variant 1.0 rifampicin
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767269 c.3900C>G synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpoC 767296 c.3927C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775847 c.2634G>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Leu missense_variant 0.91 clofazimine
bedaquiline
mmpL5 775886 c.2595A>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775895 c.2586C>A synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775910 c.2571G>T synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.65 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 775919 c.2562G>C synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.32 clofazimine
bedaquiline
mmpL5 775940 c.2541C>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.56 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.56 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.59 clofazimine
bedaquiline
mmpL5 775972 p.Ala837Pro missense_variant 0.61 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.95 clofazimine
bedaquiline
mmpL5 775991 c.2488_2490delGAGinsAC frameshift_variant&missense_variant 0.54 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>C synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 776003 c.2478C>T synonymous_variant 0.64 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.95 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.95 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.96 streptomycin
rpsL 781631 c.72G>C synonymous_variant 0.97 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.96 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.96 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.96 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.98 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.98 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.98 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.95 streptomycin Uncertain significance
rplC 800498 c.-311G>A upstream_gene_variant 1.0 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.96 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.93 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.97 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.96 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.96 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.96 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.96 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.97 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.97 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 0.97 linezolid
rplC 800600 c.-209G>A upstream_gene_variant 0.97 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.97 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.97 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.94 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.97 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.97 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.97 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.98 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.97 linezolid
rplC 800702 c.-107G>C upstream_gene_variant 0.97 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.97 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.97 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.97 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.97 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.94 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.94 linezolid
rplC 800780 c.-29C>G upstream_gene_variant 0.9 linezolid
fbiC 1303525 p.Ser199Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303827 c.897A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303871 p.Tyr314Phe missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303878 c.948G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304547 c.1617C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304802 c.1872G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304805 c.1875G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304809 p.Ser627Gly missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
atpE 1461179 c.135G>C synonymous_variant 0.91 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.91 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.91 bedaquiline
atpE 1461188 c.144G>T synonymous_variant 0.91 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.91 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.9 bedaquiline
rrs 1471514 n.-332A>C upstream_gene_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471517 n.-329T>C upstream_gene_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471541 n.-305G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471547 n.-299C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471550 n.-296T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471553 n.-293C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471562 n.-284A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472032 n.187G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472042 n.197T>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472312 n.467_468insC non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473743 n.86C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473754 n.97G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474284 n.629dupC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474292 n.635_644delTTCCTCTCCGinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474715 n.1061delA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475200 n.1543T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475221 n.1564C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475232 n.1575A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475425 n.1768G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475430 n.1773T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475482 n.1825A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475607 n.1950A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475759 n.2102_2106delCCCGCinsTCGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476741 n.3084G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476743 n.3086A>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476744 n.3087G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476746 n.3089T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476755 n.3098G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476757 n.3101delG non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
inhA 1673646 c.-556T>C upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673652 c.-550C>G upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673658 c.-544G>C upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.92 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673670 c.-532G>A upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674522 c.321G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674621 c.420C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674639 c.438C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674745 p.Tyr182Val missense_variant 0.92 ethionamide
isoniazid
inhA 1674756 c.555T>G synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674759 c.558G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674780 c.579T>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674810 c.609C>G synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 0.86 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674819 c.618G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674825 c.624C>T synonymous_variant 0.89 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674827 p.Glu209Ala missense_variant 0.89 ethionamide
isoniazid
inhA 1674839 p.Ala213Asp missense_variant 0.89 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.9 ethionamide
isoniazid
inhA 1674847 p.Gln216Lys missense_variant 0.9 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.96 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674933 c.732G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674937 p.Leu246Met missense_variant 0.96 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674963 c.762G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674967 p.Asp256Ser missense_variant 0.93 ethionamide
isoniazid
rpsA 1833616 c.75A>C synonymous_variant 0.93 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.94 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.89 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.95 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.93 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.92 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.92 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 0.92 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.91 pyrazinamide
rpsA 1833695 c.154_156delCTCinsTG frameshift_variant&missense_variant 0.91 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833772 c.231C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833865 c.324G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.97 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834210 c.669C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834219 c.678C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834387 c.846C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834462 c.921C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834468 c.927A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834483 c.942G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834522 c.981C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.97 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834723 c.1182G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Asn missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834828 c.1287C>T synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.95 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.94 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 0.92 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.9 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.9 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.9 linezolid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 c.417C>G synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.98 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517992 c.-123C>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.9 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.93 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.94 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.94 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.94 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.94 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.94 isoniazid
kasA 2518726 c.612G>A synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
Rv2477c 2782451 p.Ala531Gly missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 1.0 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782510 c.1533G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782981 c.1062G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783377 c.666C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783380 c.663C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 0.9 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783634 p.Leu137Ile missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783668 c.375G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783672 p.Arg124Gln missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859798 c.621G>C synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859822 c.597T>C synonymous_variant 1.0 clofazimine
bedaquiline
Rv2752c 3065721 c.471G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065732 c.460T>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065742 p.Thr150Ile missense_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065748 c.444T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065769 c.423C>T synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065775 c.417T>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065781 c.411C>A synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065789 c.403C>A synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065791 p.Thr134Ser missense_variant 0.88 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065799 c.393C>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065806 p.Arg129Ala missense_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065808 c.384C>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066006 c.186G>C synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066027 c.165C>G synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066030 c.162G>A synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066042 c.150T>G synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066051 c.141G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.124_126delATTinsGC frameshift_variant&missense_variant 0.91 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066071 c.121T>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 0.87 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
thyX 3067337 c.609C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067340 c.606G>A synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067343 c.603C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067421 c.525G>T synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067433 c.513C>T synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067442 c.504C>G synonymous_variant 0.86 para-aminosalicylic_acid
mtrB 3625135 c.1479A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625162 c.-252T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625168 c.-258G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625177 c.-267C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625192 c.-282G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625195 c.-285A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625741 c.-831G>A upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625747 c.867G>C synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.95 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625766 c.-857_-856delTCinsAG upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625795 c.-885G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625801 c.-891G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 0.94 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625858 c.-948C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625864 c.750T>C synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625879 c.735G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625882 c.-972G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625888 c.726G>A synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625899 p.Val239Leu missense_variant 0.91 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626735 c.-122C>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626750 c.-137T>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626768 c.582G>C synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.85 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626792 c.-179G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626825 c.-212T>G upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626840 c.-227C>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.94 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.95 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.95 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.95 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.96 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.98 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 0.99 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877794 c.714G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877821 c.687C>G synonymous_variant 0.98 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877865 c.643C>T synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877878 c.630G>A synonymous_variant 1.0 rifampicin
rpoA 3877881 c.627G>C synonymous_variant 1.0 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>A synonymous_variant 0.98 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 0.98 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.97 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.95 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 0.94 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.98 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.98 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.98 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.98 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878202 c.306G>C synonymous_variant 0.97 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878264 p.Ser82Gly missense_variant 0.95 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.95 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 0.85 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878328 c.180G>C synonymous_variant 0.83 rifampicin
rpoA 3878331 c.177A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.88 rifampicin
rpoA 3878872 c.-365G>C upstream_gene_variant 0.91 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.92 rifampicin Uncertain significance
rpoA 3878886 c.-379G>A upstream_gene_variant 0.96 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 0.96 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 0.96 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.97 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.97 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 0.97 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878962 c.-455G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879094 c.-587T>C upstream_gene_variant 0.7 rifampicin
rpoA 3879121 c.-616_-614delCTTinsAAC upstream_gene_variant 0.7 rifampicin
rpoA 3879124 c.-618_-617delTGinsGC upstream_gene_variant 0.7 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.64 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.67 rifampicin
rpoA 3879151 c.-644C>G upstream_gene_variant 0.73 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.73 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.8 rifampicin
ddn 3986622 c.-222C>T upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986631 c.-213A>T upstream_gene_variant 0.92 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.92 delamanid
pretomanid
ddn 3986646 c.-198_-196delCTCinsTG upstream_gene_variant 0.92 delamanid
pretomanid
ddn 3986656 c.-188C>G upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986665 c.-179G>C upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986696 c.-148G>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986699 c.-145C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986702 c.-142G>C upstream_gene_variant 1.0 delamanid
pretomanid
clpC1 4038308 p.Val799Asn missense_variant 1.0 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2313C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038416 c.2289C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038512 c.2193C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Ala missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038587 c.2118C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 1.0 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038657 p.Lys683Ser missense_variant 0.92 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038674 c.2031C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038902 c.1803C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.98 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039091 c.1614G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039124 c.1581C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039139 c.1566G>A synonymous_variant 0.97 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039145 c.1560G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.98 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCC frameshift_variant&missense_variant 0.98 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039217 c.1488G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039265 c.1440C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039283 c.1422C>T synonymous_variant 0.86 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.84 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.83 pyrazinamide
clpC1 4039346 c.1359G>T synonymous_variant 0.88 pyrazinamide
clpC1 4039355 c.1350G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039359 p.Ser449Asn missense_variant 0.9 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.95 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.94 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.89 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.86 pyrazinamide
clpC1 4039635 p.Glu357Leu missense_variant 0.88 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039688 c.1017G>A synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039805 c.900C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.93 pyrazinamide
clpC1 4039820 c.885T>A synonymous_variant 0.93 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.93 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039840 c.865C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.98 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040108 c.597G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040126 c.579C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040159 c.546G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040195 c.510G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040201 c.504C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040214 p.Ser164Asn missense_variant 1.0 pyrazinamide
clpC1 4040219 c.484_486delTCCinsGG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.95 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040279 c.426C>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040321 c.384C>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040345 c.360C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.95 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.94 pyrazinamide
clpC1 4040369 c.334_336delCTCinsTG frameshift_variant&synonymous_variant 0.91 pyrazinamide
clpC1 4040393 c.312G>T synonymous_variant 0.9 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>T synonymous_variant 0.91 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040636 c.69C>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040644 c.61A>C synonymous_variant 0.92 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.93 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.93 pyrazinamide
clpC1 4040674 c.31A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040675 c.30C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040690 c.15T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.93 pyrazinamide
clpC1 4040696 c.9A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040706 c.-2C>G upstream_gene_variant 0.93 pyrazinamide
clpC1 4040710 c.-6C>A upstream_gene_variant 0.92 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 0.92 pyrazinamide
glpK 4138457 p.Asp433Glu missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138464 p.Gly431Ala missense_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138489 c.1267T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138495 p.Gln421Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138500 p.Arg419His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138505 c.1251T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138541 c.1215C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138567 p.Thr397Ala missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139621 c.135G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240729 c.867C>G synonymous_variant 0.93 ethambutol
embC 4240736 p.Ser292Ala missense_variant 0.95 ethambutol
embC 4240756 c.894G>C synonymous_variant 0.95 ethambutol
embC 4240774 c.912C>G synonymous_variant 0.95 ethambutol
embC 4240778 c.916_918delCATinsAC frameshift_variant&missense_variant 0.95 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.95 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.95 ethambutol
embC 4240790 p.Met310Leu missense_variant 0.95 ethambutol
embC 4240807 c.945C>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embC 4240816 c.954C>T synonymous_variant 0.92 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.9 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.9 ethambutol
embC 4240954 c.1092T>C synonymous_variant 1.0 ethambutol
embC 4240960 c.1098G>C synonymous_variant 1.0 ethambutol
embC 4240963 c.1101G>C synonymous_variant 1.0 ethambutol
embC 4241002 c.1140G>C synonymous_variant 1.0 ethambutol
embC 4241008 c.1146G>C synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>G synonymous_variant 1.0 ethambutol
embC 4241026 c.1164C>G synonymous_variant 1.0 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.96 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.96 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.97 ethambutol
embC 4241063 c.1201_1203delATCinsCG frameshift_variant&missense_variant 0.97 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.97 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.97 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.96 ethambutol
embC 4241131 c.1269G>C synonymous_variant 1.0 ethambutol
embC 4241412 p.Ile517Thr missense_variant 1.0 ethambutol
embC 4241439 p.Ser526Thr missense_variant 0.95 ethambutol
embC 4241443 c.1581C>G synonymous_variant 0.95 ethambutol
embC 4241452 c.1590G>C synonymous_variant 0.95 ethambutol
embC 4241464 c.1602C>G synonymous_variant 0.95 ethambutol
embC 4241470 c.1608C>G synonymous_variant 0.94 ethambutol
embC 4241480 p.Leu540Val missense_variant 1.0 ethambutol
embC 4241483 p.Val541Leu missense_variant 1.0 ethambutol
embC 4241494 c.1632C>G synonymous_variant 1.0 ethambutol
embA 4244669 c.1437G>C synonymous_variant 1.0 ethambutol
embA 4244678 c.1446G>C synonymous_variant 1.0 ethambutol
embA 4244681 c.1449A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244684 c.1452C>G synonymous_variant 1.0 ethambutol
embA 4244694 p.Lys488Val missense_variant 1.0 ethambutol
embA 4244699 c.1467C>G synonymous_variant 1.0 ethambutol
embA 4244723 c.1491G>A synonymous_variant 1.0 ethambutol
embA 4245243 p.Ala671Ser missense_variant 0.8 ethambutol
embA 4245248 c.2016G>C synonymous_variant 0.73 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.67 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embA 4245264 p.Asp678Asn missense_variant 0.67 ethambutol Uncertain significance
embA 4245270 p.Arg680Lys missense_variant 0.67 ethambutol
embA 4245281 c.2049C>G synonymous_variant 0.8 ethambutol
embA 4245282 c.2050_2052delATCinsGG frameshift_variant&missense_variant 0.8 ethambutol Uncertain significance
embA 4245290 c.2058C>G synonymous_variant 0.8 ethambutol
embA 4245293 c.2061T>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4247426 p.Gly305Gln missense_variant 0.91 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.94 ethambutol
embB 4247446 p.Asp311Glu missense_variant 0.95 ethambutol
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.96 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.96 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.96 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.95 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.92 ethambutol
embB 4248232 c.1719G>C synonymous_variant 1.0 ethambutol
embB 4248242 p.Val577Ile missense_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248256 c.1743C>G synonymous_variant 1.0 ethambutol
embB 4248257 p.Met582Val missense_variant 1.0 ethambutol
embB 4248264 p.Phe584Cys missense_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248299 c.1786_1788delTTCinsAG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248304 c.1791G>C synonymous_variant 1.0 ethambutol
embB 4248403 c.1890G>C synonymous_variant 1.0 ethambutol
embB 4248407 c.1894_1896delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248410 c.1897_1899delTTCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248416 c.1903_1905delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4248421 c.1908G>C synonymous_variant 1.0 ethambutol
embB 4248425 c.1912T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4248460 c.1947C>G synonymous_variant 0.94 ethambutol
embB 4248466 c.1953C>T synonymous_variant 0.93 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.92 ethambutol
embB 4249433 p.Leu974Val missense_variant 0.92 ethambutol Uncertain significance
embB 4249441 c.2928A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.93 ethambutol
embB 4249454 p.Thr981Gln missense_variant 0.94 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.95 ethambutol
embB 4249483 c.2970C>G synonymous_variant 0.94 ethambutol
embB 4249486 c.2973T>C synonymous_variant 0.94 ethambutol
embB 4249487 c.2974T>C synonymous_variant 1.0 ethambutol
embB 4249618 c.3105C>T synonymous_variant 1.0 ethambutol
embB 4249624 c.3111C>G synonymous_variant 1.0 ethambutol
embB 4249627 c.3114G>C synonymous_variant 1.0 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249654 p.His1047Gln missense_variant 1.0 ethambutol
embB 4249657 c.3144C>G synonymous_variant 1.0 ethambutol
embB 4249661 c.3148_3150delGCCinsTG frameshift_variant&missense_variant 1.0 ethambutol
embB 4249665 p.Thr1051Ser missense_variant 1.0 ethambutol
embB 4249686 p.Ala1058Gly missense_variant 1.0 ethambutol
embB 4249690 c.3177C>G synonymous_variant 1.0 ethambutol
embB 4249693 c.3180T>C synonymous_variant 1.0 ethambutol
embB 4249702 c.3189C>A synonymous_variant 1.0 ethambutol
aftB 4267562 c.1275C>T synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4267577 c.1260C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
aftB 4267601 c.1236C>G synonymous_variant 0.95 ethambutol
aftB 4267604 c.1233C>G synonymous_variant 0.95 ethambutol
aftB 4267619 c.1218C>G synonymous_variant 0.95 ethambutol
aftB 4267622 c.1215G>C synonymous_variant 1.0 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 1.0 ethambutol
aftB 4267635 p.Arg401Lys missense_variant 1.0 ethambutol
aftB 4267647 p.Asp397Ser missense_variant 1.0 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim