Run ID: ERR176778
Sample name:
Date: 2024-10-04T20:16:52.325131
Number of reads: 282298
Percentage reads mapped: 9.1
Median coverage: 1.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.99 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.96 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | p.Ser140Asn | Uncertain significance | Mutation from literature |
| ethambutol | embB | p.Asp311Gly | Mutation from literature | |
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| katG | 2155693 | p.Ser140Asn | missense_variant | 1.0 | isoniazid | Uncertain significance | Mutation from literature |
| embB | 4247445 | p.Asp311Gly | missense_variant | 0.93 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 699 | c.699G>C | synonymous_variant | 0.9 | isoniazid | Not assoc w R - Interim |
| dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 714 | c.714C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 765 | c.766_767insCG | frameshift_variant | 0.97 | isoniazid | Uncertain significance |
| dnaA | 769 | c.770_771delCA | frameshift_variant | 0.97 | isoniazid | Uncertain significance |
| dnaA | 793 | p.Val265Ile | missense_variant | 0.97 | isoniazid | Uncertain significance |
| dnaA | 802 | c.802C>T | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 805 | c.805T>C | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 0.97 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 0.96 | isoniazid | |
| dnaA | 837 | c.837A>G | synonymous_variant | 0.96 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 864 | c.864C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 877 | c.877T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 888 | c.888C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 909 | c.909A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 912 | c.912T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 921 | c.921A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 927 | c.927G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 933 | c.933C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1008 | c.1008G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1014 | c.1014C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1023 | c.1023C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1029 | c.1029C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1035 | c.1035A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1038 | c.1038A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1047 | p.Glu349Asp | missense_variant | 1.0 | isoniazid | |
| dnaA | 1050 | c.1050G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1055 | p.Ala352Asp | missense_variant | 1.0 | isoniazid | |
| dnaA | 1059 | c.1059C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1098 | c.1098A>G | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6160 | c.921C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6190 | c.951A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6532 | c.-770C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6535 | c.-767C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6547 | c.-755T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6550 | c.1311A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6551 | c.1312T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6556 | c.-746C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6577 | c.1338T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6583 | c.-719G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6631 | c.-671C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6680 | c.1441C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6724 | c.-578G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6775 | c.-527G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6802 | c.1563G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6824 | c.1585C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7081 | c.-221T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7114 | c.-188C>G | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>T | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7165 | c.-137C>A | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7189 | c.-113C>T | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7210 | p.Asp657Glu | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7213 | c.-89G>A | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7216 | c.-86G>T | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7225 | c.-77T>C | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7237 | c.-65C>T | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7243 | c.-59G>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7246 | c.2007T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7252 | c.-50G>T | upstream_gene_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7258 | c.-44G>T | upstream_gene_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7415 | c.114C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7448 | c.147G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>G | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7529 | c.228G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7592 | c.291G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7655 | c.354G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7775 | c.474C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7778 | c.477G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8312 | c.1011G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8327 | c.1026C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8342 | c.1041G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8354 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8357 | c.1056G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8367 | c.1066C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8400 | p.Asp367Asn | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8433 | p.Thr378Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8442 | c.1141C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8477 | c.1176C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8513 | c.1212C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8588 | p.Glu429Asp | missense_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8597 | c.1296C>G | synonymous_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8645 | c.1344C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8708 | c.1407G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8720 | c.1419G>A | synonymous_variant | 0.86 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 0.8 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8796 | p.Ile499Val | missense_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 0.94 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8817 | p.Ser506Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8876 | c.1575C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8924 | c.1623C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8951 | c.1650G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8967 | p.Ala556Asn | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9038 | c.1737C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9044 | c.1743C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9062 | c.1761C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9065 | c.1764C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9092 | c.1791C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9101 | c.1800A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9207 | p.Lys636Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9213 | p.Thr638Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9248 | c.1947G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9278 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9284 | c.1983T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9300 | p.Ala667Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 0.98 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9332 | p.Asn677Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9356 | c.2055G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9369 | c.2068C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9389 | c.2088C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491491 | p.Pro237Thr | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491496 | c.714C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491512 | p.Asn244Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491563 | c.781_782delAGinsTC | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491603 | p.Ala274Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491605 | c.823C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491610 | c.828A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| mshA | 575656 | c.309G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575665 | c.318G>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575686 | c.339G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575704 | c.357T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575705 | c.358_360delTTGinsCTC | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575744 | p.Ala133Thr | missense_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 575749 | c.402C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575761 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575795 | p.Ile150Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575800 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575803 | c.456C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575821 | c.474G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575839 | c.492G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575905 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575908 | c.561A>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575911 | c.564G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575917 | p.Asp190Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575924 | p.Gly193Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575935 | c.588G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 0.91 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 0.93 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620373 | c.483C>A | synonymous_variant | 0.94 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 0.9 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 0.9 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| ccsA | 620418 | c.528G>C | synonymous_variant | 0.9 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620430 | c.540C>T | synonymous_variant | 0.88 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620439 | c.549T>G | synonymous_variant | 0.87 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620442 | c.552G>T | synonymous_variant | 0.87 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 0.87 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620460 | c.570T>C | synonymous_variant | 0.9 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 0.93 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620634 | c.744C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620703 | c.813G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620709 | c.819G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| Rv0565c | 657668 | c.-200_-198delACCinsGCG | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657686 | c.-216C>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657690 | c.-220C>A | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731732 | c.-198G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731753 | c.-177A>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731807 | c.-123C>T | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731819 | c.-111G>C | upstream_gene_variant | 0.94 | isoniazid | |
| hadA | 731823 | c.-107_-105delCTGinsATC | upstream_gene_variant | 0.92 | isoniazid | |
| nusG | 734407 | p.Val52Ile | missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734508 | c.255C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734814 | c.561G>C | synonymous_variant | 0.91 | rifampicin | |
| nusG | 734820 | c.567A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734826 | c.573A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734850 | c.597C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734863 | p.Thr204Ser | missense_variant | 1.0 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760060 | p.Tyr85Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 760068 | c.262_264delTCTinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760106 | c.300G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760115 | c.309C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760244 | c.438G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760253 | c.447T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760316 | c.510C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760337 | c.531C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760343 | c.537G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760357 | p.Thr184Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760445 | c.639C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760511 | c.705G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760514 | c.708C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 0.96 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.97 | rifampicin | |
| rpoB | 760611 | c.805_807delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760622 | c.816C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760629 | c.823C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 760965 | p.Met387Leu | missense_variant | 0.9 | rifampicin | Uncertain significance |
| rpoB | 760991 | c.1185G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760997 | c.1191G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761054 | c.1248G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761124 | c.1318C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761132 | c.1326G>C | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761252 | c.1446C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761258 | c.1452G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761318 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761437 | p.Ala544Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761439 | p.Asp545Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761661 | c.1855C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761816 | c.2010C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761819 | c.2013G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761999 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762014 | c.2208C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762038 | c.2232C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762251 | c.2445G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762275 | c.2469C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762488 | c.2682G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762503 | c.-867G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.97 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762560 | c.-810A>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762563 | c.-807G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762575 | c.-795C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762760 | p.Cys985Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762786 | p.Val994Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 762791 | c.-579G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762799 | p.Ala998Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762827 | c.-543G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762833 | c.3027C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762851 | c.-519C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762863 | c.-507T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762879 | p.Met1025Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762917 | c.-453C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763004 | c.3198G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763007 | c.3201C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763139 | c.-231C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763142 | c.-228C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763172 | c.3366G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763375 | c.6C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763396 | c.27A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763402 | c.33C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763411 | c.42T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763420 | c.51G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763429 | c.60C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61_63delAGGinsCGT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763435 | c.66A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763531 | c.162G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763781 | p.Ser138Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763801 | c.432C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763831 | c.462A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763837 | c.468G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763925 | p.Ala186Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 763930 | c.561G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763940 | p.Ala191Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763947 | p.Ala193Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763951 | c.582G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763960 | c.591T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763963 | c.594C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763972 | c.603C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764084 | p.Asn239Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 764095 | c.726C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 764134 | c.765C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764143 | c.774G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764147 | p.Ser260Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764153 | p.Gln262Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764182 | p.Asp271Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764194 | c.825G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764195 | p.Ser276Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764239 | c.870T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764245 | c.876C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764248 | c.879C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764285 | p.Gly306Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 764293 | c.924G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764317 | c.948C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764320 | c.951C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764392 | c.1023C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764410 | c.1041G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764485 | c.1116G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764491 | c.1122G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764548 | c.1179G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764585 | c.1216_1218delCTCinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764602 | c.1233C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764644 | c.1275G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764701 | c.1332C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764755 | c.1386C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764797 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764812 | c.1443C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519_1521delTTGinsCTC | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764926 | c.1557C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764953 | c.1584G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764956 | c.1587T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765004 | c.1635G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765011 | c.1642_1644delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765016 | c.1647C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765055 | c.1686C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 765085 | c.1716T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765121 | c.1752G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765425 | p.Lys686Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765445 | c.2076G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765451 | c.2082C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765452 | p.Ala695Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765458 | p.Ile697Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765466 | c.2097C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765469 | c.2100G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765480 | p.Tyr704Phe | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765496 | c.2127C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765508 | c.2139C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765591 | p.Arg741Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765596 | p.Lys743Gln | missense_variant | 0.92 | rifampicin | |
| rpoC | 765607 | c.2238C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765805 | c.2436C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765812 | c.2443_2445delCGAinsAGG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765817 | c.2448G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765883 | c.2514C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765946 | c.2577C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765947 | c.2578T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765961 | c.2592G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765962 | c.2593_2595delTTGinsCTT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765970 | c.2601C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766003 | c.2634G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766369 | c.3000C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766375 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766390 | c.3021C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766423 | c.3054T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766459 | c.3090G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | p.Val1039Ile | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoC | 766492 | c.3123T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766493 | p.Gly1042Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766537 | c.3168G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766546 | c.3177G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766579 | c.3210C>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 766582 | c.3213C>T | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766588 | c.3219G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766681 | c.3312C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766711 | c.3342C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766712 | p.Ser1115Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766720 | c.3351C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766741 | c.3372G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766771 | c.3402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766798 | c.3429C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766801 | c.3432C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766837 | c.3468G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766858 | c.3489C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766867 | c.3498C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766882 | c.3513C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766951 | c.3582G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766975 | c.3606C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767008 | c.3639G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767020 | c.3651C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767068 | c.3699G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | p.Asn1246Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767185 | c.3816G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767200 | c.3831G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767203 | c.3834C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 776672 | p.Val603Ile | missense_variant | 0.6 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776681 | p.Leu600Phe | missense_variant | 0.4 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776686 | p.Ser599Ala | missense_variant | 0.4 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776695 | p.Val596Ile | missense_variant | 0.4 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776704 | p.Asp593Asn | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776706 | p.Tyr592Phe | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776715 | p.Lys589Pro | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776732 | p.Ser583Asn | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| clofazimine | Uncertain significance | |||||
| mmpL5 | 776735 | c.1746C>G | synonymous_variant | 0.64 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777142 | p.Val447Leu | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777173 | c.1308C>G | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777179 | c.1302G>C | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777188 | c.1293T>C | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777194 | p.Glu429Gln | missense_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777203 | c.1278G>T | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777206 | c.1275A>G | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777227 | c.1254C>G | synonymous_variant | 0.95 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 777245 | c.1236G>C | synonymous_variant | 0.92 | bedaquiline | |
| clofazimine | ||||||
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781652 | c.93T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781676 | c.117C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781703 | c.144G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781737 | p.Gln60Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781862 | c.303G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781880 | c.321C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781901 | c.342C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800564 | c.-245C>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800585 | c.-224T>C | upstream_gene_variant | 0.92 | linezolid | |
| rplC | 800594 | c.-215C>G | upstream_gene_variant | 0.88 | linezolid | |
| rplC | 800597 | c.-212A>T | upstream_gene_variant | 0.88 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.88 | linezolid | |
| rplC | 800603 | c.-206G>T | upstream_gene_variant | 0.88 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.92 | linezolid | |
| rplC | 800633 | c.-176T>C | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800693 | c.-116A>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800892 | c.84G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800919 | c.111C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 0.94 | linezolid | |
| rplC | 800946 | c.138T>G | synonymous_variant | 0.93 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 800955 | c.147C>T | synonymous_variant | 0.92 | linezolid | |
| rplC | 800961 | c.153G>A | synonymous_variant | 0.92 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.92 | linezolid | Not assoc w R - Interim |
| rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801186 | c.378C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801222 | c.414T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801231 | c.423C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801237 | c.429G>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801252 | c.444G>C | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303492 | c.562T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303506 | c.576C>T | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303515 | c.585G>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303531 | p.Met201Leu | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303536 | c.606G>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303548 | c.618G>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303551 | c.621G>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303554 | c.624G>T | synonymous_variant | 0.93 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.96 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.96 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.97 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304694 | c.1764A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304718 | c.1788C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304757 | c.1827A>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304787 | c.1857T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304790 | c.1860C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304793 | c.1863C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304797 | p.Ala623Lys | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304820 | c.1890G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304823 | c.1893C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304931 | c.2001C>G | synonymous_variant | 0.9 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.91 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304946 | c.2016G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304958 | c.2028T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304961 | c.2031C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304967 | c.2037G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304995 | p.Leu689Met | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305007 | p.Ile693Val | missense_variant | 1.0 | pretomanid | |
| delamanid | Uncertain significance | |||||
| clofazimine | Uncertain significance | |||||
| fbiC | 1305030 | c.2100G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305033 | c.2103T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305043 | c.2113_2115delTCAinsAGT | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305063 | c.2133G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364767 | c.355_357delAGGinsCGC | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364814 | c.402C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364877 | c.465G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364887 | c.475_477delTTAinsCTG | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1461042 | c.-2delA | upstream_gene_variant | 0.92 | bedaquiline | |
| atpE | 1461050 | c.6C>T | synonymous_variant | 0.93 | bedaquiline | |
| atpE | 1461071 | c.27C>G | synonymous_variant | 0.94 | bedaquiline | |
| atpE | 1461101 | c.57T>C | synonymous_variant | 0.95 | bedaquiline | |
| atpE | 1461107 | c.63C>A | synonymous_variant | 0.89 | bedaquiline | |
| atpE | 1461113 | c.69C>T | synonymous_variant | 0.94 | bedaquiline | |
| atpE | 1461131 | c.87T>C | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 0.92 | bedaquiline | |
| atpE | 1461137 | c.93C>G | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461147 | c.103_105delCTTinsTTG | synonymous_variant | 0.9 | bedaquiline | |
| atpE | 1461153 | p.Ser37Ala | missense_variant | 0.9 | bedaquiline | Uncertain significance |
| atpE | 1461170 | c.126A>G | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461182 | c.138A>G | synonymous_variant | 0.94 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 0.94 | bedaquiline | |
| atpE | 1461188 | c.144G>A | synonymous_variant | 0.94 | bedaquiline | |
| atpE | 1461197 | c.153A>T | synonymous_variant | 0.94 | bedaquiline | |
| atpE | 1461212 | c.168C>G | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461215 | c.171C>G | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461224 | c.180T>C | synonymous_variant | 0.92 | bedaquiline | |
| atpE | 1461233 | c.189A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461254 | c.210T>C | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471926 | n.81C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472289 | n.444T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472297 | n.453_465delGTCCGGGTTCTCT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472313 | n.468delGinsCA | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | Uncertain significance | |||||
| amikacin | ||||||
| rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472844 | n.1000dupG | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472849 | n.1005delT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472856 | n.1012delA | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472859 | n.1014G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472861 | n.1018dupT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTC | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473696 | n.39T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473697 | n.40C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473743 | n.86C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473811 | n.154C>A | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
| linezolid | ||||||
| rrl | 1473813 | n.156C>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
| linezolid | ||||||
| rrl | 1473814 | n.157A>C | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473829 | n.172G>C | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473830 | n.173T>G | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
| linezolid | ||||||
| rrl | 1473831 | n.174G>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473833 | n.176G>T | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
| linezolid | ||||||
| rrl | 1473836 | n.179A>G | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474202 | n.545T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474282 | n.625G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474287 | n.630delTinsCTCG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474289 | n.632C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474293 | n.637_647delCCTCTCCGGAG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474306 | n.649A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474446 | n.789C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474629 | n.972G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474640 | n.983C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474710 | n.1053delTinsGCAA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474720 | n.1063C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474722 | n.1065T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474905 | n.1248T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475366 | n.1709G>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475379 | n.1722G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475398 | n.1741C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475403 | n.1746T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475430 | n.1773T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475458 | n.1801C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475532 | n.1875A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475643 | n.1986C>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
| linezolid | ||||||
| rrl | 1475647 | n.1990G>C | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1475991 | n.2334T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476025 | n.2368G>A | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>G | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>A | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476105 | n.2448G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476165 | n.2508T>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036delGinsCA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673697 | c.-505G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673706 | c.-496C>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673710 | c.-492_-490delCTAinsATC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673748 | c.-454A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673749 | c.-453_-452delAAinsCG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673757 | c.-445G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673758 | c.-444A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673778 | c.-424C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673799 | c.-403T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673808 | c.-394A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673816 | c.-386G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673941 | c.-261_-259delGCCinsTCG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673946 | c.-256C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673960 | c.-242_-241delCAinsTC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674502 | p.Thr101Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674516 | c.315C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674534 | c.333G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| inhA | 1674540 | c.339C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674552 | c.351C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674555 | c.354G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674561 | c.360C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674600 | c.399G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674601 | p.Leu134Thr | missense_variant | 0.88 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674620 | p.Pro140Arg | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674628 | c.427_428delTCinsAG | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674639 | c.438C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674687 | c.486G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833537 | c.-5_-1delACAATinsCCAC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833547 | c.6G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833628 | c.87G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833685 | c.144G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833730 | c.189C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833739 | c.198C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833778 | c.237C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833781 | c.240T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833805 | c.264C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833820 | c.279G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833829 | c.288A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833892 | c.351G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833901 | c.360G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833970 | c.429G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833988 | c.447C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834069 | c.528G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834096 | c.555G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834282 | c.741C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834345 | c.804C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834387 | c.846C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834520 | p.Ala327Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834552 | c.1011G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834556 | p.Ala339Gln | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834612 | c.1071G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834645 | c.1104C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Pro | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.9 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.82 | linezolid | |
| tsnR | 1853375 | c.-231G>C | upstream_gene_variant | 0.8 | linezolid | |
| tsnR | 1853417 | c.-189G>C | upstream_gene_variant | 0.82 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.82 | linezolid | |
| katG | 2155654 | p.Lys153Arg | missense_variant | 1.0 | isoniazid | |
| katG | 2155661 | p.Val151Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155668 | c.444G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155680 | c.432G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517917 | c.-198G>T | upstream_gene_variant | 0.98 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517993 | c.-122G>A | upstream_gene_variant | 0.96 | isoniazid | |
| kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518138 | c.24T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518150 | c.36C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518152 | p.Ser13Asn | missense_variant | 1.0 | isoniazid | |
| kasA | 2518156 | c.42T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518159 | c.45G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518174 | c.60A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518180 | c.66G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518187 | p.Ile25Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518193 | p.Pro27Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518219 | c.105T>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518223 | c.109T>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518234 | c.120G>A | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518496 | p.Leu128Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518540 | c.426T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518555 | c.441C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518564 | c.450C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518595 | c.481_483delCGCinsAGG | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518606 | c.492G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518618 | c.504G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519152 | c.1038G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2519158 | c.1044C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519170 | c.1056G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519182 | c.1068G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519185 | c.1071C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519188 | c.1074G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519194 | c.1080G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519195 | p.Thr361Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2519203 | c.1089C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519224 | c.1110C>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726597 | c.405C>G | synonymous_variant | 0.9 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 0.9 | isoniazid | |
| ahpC | 2726612 | c.420C>G | synonymous_variant | 0.94 | isoniazid | |
| ahpC | 2726633 | c.441C>G | synonymous_variant | 0.94 | isoniazid | |
| ahpC | 2726638 | p.Ala149Val | missense_variant | 0.94 | isoniazid | |
| ahpC | 2726648 | c.456T>C | synonymous_variant | 0.94 | isoniazid | |
| ahpC | 2726657 | c.465A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726669 | c.477T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726675 | c.483A>G | synonymous_variant | 0.92 | isoniazid | |
| ahpC | 2726681 | c.489A>G | synonymous_variant | 0.92 | isoniazid | |
| folC | 2746663 | c.936T>C | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746666 | c.933C>G | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746677 | p.Ser308Ala | missense_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746678 | c.921T>G | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746684 | c.915C>G | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746687 | c.912C>G | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746690 | p.Val303Ala | missense_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746693 | c.906G>C | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
| folC | 2746714 | c.885T>C | synonymous_variant | 0.85 | para-aminosalicylic_acid | |
| folC | 2747302 | c.297A>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| folC | 2747314 | c.285A>C | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747326 | c.273G>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747334 | c.265C>T | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747341 | p.Val86Leu | missense_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747346 | c.253C>T | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747359 | c.240C>G | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747365 | c.234G>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747368 | c.231G>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747371 | c.228C>G | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| Rv2477c | 2782414 | p.Asp543Glu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782419 | p.Val542Ile | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782432 | c.1611G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782453 | c.1590C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782462 | c.1581C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782495 | p.Asp516Glu | missense_variant | 1.0 | kanamycin | Uncertain significance |
| levofloxacin | Uncertain significance | |||||
| moxifloxacin | Uncertain significance | |||||
| streptomycin | ||||||
| rifampicin | Uncertain significance | |||||
| ethambutol | ||||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782516 | c.1527C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783005 | c.1038C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783014 | p.Ser343Thr | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783155 | c.888C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.95 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.94 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783215 | c.828G>C | synonymous_variant | 0.9 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783497 | c.544_546delTTGinsCTC | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783509 | c.534C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783539 | c.504G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| thyA | 3073839 | c.633T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073888 | p.Ser195Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073890 | c.580_582delTTGinsCTC | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073893 | c.579C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073902 | c.570C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3625042 | c.-132C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625045 | c.-135C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625054 | c.-144C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625063 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
| bedaquiline | Uncertain significance | |||||
| lpqB | 3625069 | c.-161_-159delCTTinsTTG | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625078 | c.-168G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625095 | p.Glu507Lys | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625117 | c.-207T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625122 | c.-212C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625135 | c.-225A>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625144 | c.-234G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625149 | p.Val489Ile | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625162 | c.1452T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625168 | c.-258G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625183 | c.-273G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625243 | c.-333T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625246 | c.-336G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625283 | p.Val444Ala | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625291 | p.Glu441Asp | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625312 | c.-402G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625336 | c.-426C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625351 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625357 | c.-447T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625369 | c.-459G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625723 | c.-813C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3625762 | c.852A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625766 | p.Ser283His | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625795 | c.-885G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625798 | c.-888G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625804 | c.-896_-894delAGGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625845 | p.Ser257Thr | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625846 | c.-936G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625852 | c.-942A>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625855 | c.759G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625867 | c.747A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625876 | c.738G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625882 | c.732G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626741 | c.609C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626750 | c.-137T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626774 | c.-163_-161delAGGinsCGT | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626825 | c.525T>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626843 | c.-230G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626858 | c.-245A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626978 | p.Asp124Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626992 | c.-379C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626995 | c.-382C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626999 | c.351G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627002 | c.-389G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627005 | c.-392G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627014 | c.-401G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627017 | c.-404G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627041 | p.Ile103Val | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627215 | c.-602G>C | upstream_gene_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627227 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627230 | c.-617G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627299 | c.-688_-686delTTGinsCTC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627305 | p.Ala15Pro | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627311 | c.39C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627320 | c.-707C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627325 | c.-712T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627343 | p.Thr3Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| rpoA | 3877587 | c.921A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877662 | c.846C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877671 | c.837C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | c.831G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877707 | c.801G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877728 | c.780C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877740 | c.768G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877749 | c.759C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.735_738delGTCAinsCAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877821 | c.687C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877860 | c.648C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877881 | c.627G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877884 | c.624G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877893 | c.615C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877923 | c.585C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878124 | c.384G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878142 | p.Gly122Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878175 | c.333G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878244 | c.264G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878250 | c.258C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878253 | c.255G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>T | synonymous_variant | 0.94 | rifampicin | |
| rpoA | 3878316 | c.192C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878358 | c.150C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878373 | c.135G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3879073 | c.-566A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879082 | c.-575C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-583_-581delACAinsTCG | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3879091 | c.-584C>T | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3879117 | c.-610C>T | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879124 | c.-618_-617delTGinsGC | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 0.93 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.91 | rifampicin | |
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986657 | c.-187C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986661 | c.-183C>A | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986673 | c.-171C>T | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986681 | c.-163C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986696 | c.-148G>T | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986699 | c.-145C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clpC1 | 4038293 | c.2412G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038302 | c.2403C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038308 | p.Val799Leu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038317 | c.2388G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038325 | p.Val794Ile | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038335 | c.2370C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038350 | c.2355C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038401 | c.2302_2304delTTGinsCTC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038407 | c.2298G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038416 | c.2289C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038474 | p.Ser744Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038490 | p.Ala739Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038491 | c.2214C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038587 | c.2116_2118delCGCinsAGG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038644 | p.Glu687Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>G | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038679 | p.Pro676Ala | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038743 | c.1962G>A | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038764 | c.1941C>A | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038905 | c.1800A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038932 | c.1773G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038986 | c.1719C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039009 | c.1696C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039073 | c.1632C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039079 | c.1626C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039082 | c.1623C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | c.1536A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039193 | c.1512C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039199 | p.Ala502Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039220 | c.1485G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039310 | c.1395A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039316 | c.1389G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039334 | c.1371G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039338 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039347 | p.Arg453Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039364 | c.1341C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039394 | c.1311G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039553 | c.1152C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039592 | c.1113G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039628 | c.1077C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039655 | c.1050G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039670 | c.1035G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039691 | c.1014G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039739 | c.966C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039829 | c.874_876delTTGinsCTC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039832 | c.873C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039901 | c.804C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039907 | c.798G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039922 | c.783C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039925 | c.780C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039949 | c.756G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039955 | c.750G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039985 | c.720G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039988 | c.717C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040018 | c.687G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040123 | c.582G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040144 | c.561G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040257 | p.Ala150Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040270 | c.435C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040276 | c.429C>G | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040306 | c.399G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040312 | c.393G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>T | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040414 | c.291G>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040570 | c.135C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040690 | c.15T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040695 | c.10C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040696 | c.9A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040699 | c.6C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040711 | c.-7G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044177 | c.105C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044180 | p.Asp34Glu | missense_variant | 1.0 | pyrazinamide | |
| panD | 4044188 | c.94T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044195 | c.87T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044210 | c.72C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044213 | c.69C>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044225 | c.57C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044231 | p.Cys17Lys | missense_variant | 1.0 | pyrazinamide | |
| panD | 4044237 | c.45G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044270 | c.12G>A | synonymous_variant | 1.0 | pyrazinamide | |
| glpK | 4138562 | c.1194G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138568 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138589 | c.1167C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138596 | p.Phe387Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138604 | c.1150_1152delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139637 | p.Ala40Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139639 | p.Val39Ile | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139648 | c.108T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139652 | p.His35Gly | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| embC | 4240717 | c.855T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240729 | c.867C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240736 | p.Ser292Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240759 | c.897C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240765 | c.903C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240795 | c.933C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240822 | c.960C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240825 | c.963G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240826 | p.Ala322Ser | missense_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240843 | c.981C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| embB | 4247440 | c.927C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 0.91 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 0.91 | ethambutol | |
| embB | 4247476 | c.963C>G | synonymous_variant | 0.91 | ethambutol | |
| ethA | 4326280 | c.1194G>T | synonymous_variant | 0.8 | ethionamide | |
| ethA | 4326304 | c.1170C>G | synonymous_variant | 0.73 | ethionamide | |
| ethA | 4326307 | c.1167C>A | synonymous_variant | 0.73 | ethionamide | |
| ethA | 4326310 | c.1164T>C | synonymous_variant | 0.73 | ethionamide | |
| ethA | 4326322 | p.Val384Ile | missense_variant | 0.8 | ethionamide | |
| ethA | 4326329 | p.Tyr382Phe | missense_variant | 0.8 | ethionamide | |
| ethA | 4326331 | c.1143C>G | synonymous_variant | 0.8 | ethionamide | |
| ethA | 4326343 | p.Ile377Met | missense_variant | 0.8 | ethionamide | |
| ethA | 4326347 | p.Gly376His | missense_variant | 0.8 | ethionamide |
