TB-Profiler result

Run: ERR3797047

Summary

Run ID: ERR3797047

Sample name:

Date: 2024-04-15T11:31:06.889998

Number of reads: 348033

Percentage reads mapped: 15.56

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.95
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid kasA p.Arg121Lys Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.9 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
kasA 2518476 p.Arg121Lys missense_variant 0.9 isoniazid Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 543 c.543C>G synonymous_variant 1.0 isoniazid
dnaA 558 c.558G>C synonymous_variant 1.0 isoniazid
dnaA 567 c.567C>G synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 1.0 isoniazid
dnaA 588 c.588A>C synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 1.0 isoniazid
dnaA 597 c.597C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 723 c.723A>G synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 804 c.804G>C synonymous_variant 1.0 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
gyrB 6280 c.1041T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6325 c.-977C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Arg missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6361 c.-941G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6367 c.-935C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6370 c.1131C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6531 p.Ser431Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6547 c.-755T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6551 c.1312T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6604 c.-698G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6607 c.-695T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6608 p.Val457Ile missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6766 c.-536G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6821 c.1582_1584delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6850 c.-452C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6896 p.Arg553Lys missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6926 c.1687_1689delTTGinsCC frameshift_variant&missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6955 c.-347G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6961 c.-341G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6965 p.Ser576Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6988 c.-314C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7005 p.Gly589Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7022 p.Leu595Lys missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7418 c.117C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7466 c.165G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7513 p.Ala71Val missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7611 c.310_312delTCGinsGC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7614 p.Leu105Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7748 c.447A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7758 c.457_459delATCinsGT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8190 c.889_891delGCCinsTG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8237 c.936A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8271 p.Ala324Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8345 c.1044C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8400 p.Asp367Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8429 c.1128C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8547 c.1246_1248delATCinsGG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8567 p.Ile422Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8579 p.Asp426Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8612 c.1311C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8741 c.1440C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8792 c.1491G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8814 c.1513_1515delGTCinsAG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8855 c.1554C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8951 c.1650G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9016 p.Thr572Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9114 c.1813_1815delGAGinsAC frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9176 c.1875G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9206 c.1905C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9207 p.Lys636Arg missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 9213 p.Thr638Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 9218 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 p.Asp655Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491022 c.240C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491034 c.252C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491077 p.Asn99Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491135 p.Tyr118Phe missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491505 c.723G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
mshA 575627 c.280_282delGCAinsTG frameshift_variant&stop_gained 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575635 c.288A>C synonymous_variant 0.95 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575650 c.303G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575652 p.Arg102Gln missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575906 c.559_561delGCAinsTG frameshift_variant&stop_gained 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575917 p.Asp190Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575923 c.577_578delGG frameshift_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575929 c.582_583insCG frameshift_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575932 c.585G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575935 c.588G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575977 c.630G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575983 c.636G>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620238 c.348G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620247 p.Leu119Phe missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620257 c.367_369delATCinsGG frameshift_variant&missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620264 p.Gly125Ala missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>G synonymous_variant 1.0 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620287 p.Arg133Ala missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620311 p.Leu141Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620329 p.Ile147Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620658 c.768C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620754 c.864G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620762 p.Lys291Arg missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620791 c.901_903delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
hadA 732268 c.339T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732269 p.Glu114Gln missense_variant 1.0 isoniazid
hadA 732281 p.Thr118Ala missense_variant 1.0 isoniazid
hadA 732284 c.355_357delCAGinsGC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732328 p.Asp133Glu missense_variant 1.0 isoniazid Uncertain significance
hadA 732329 p.Leu134Ile missense_variant 1.0 isoniazid
hadA 732341 p.Thr138Cys missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732353 c.424C>T synonymous_variant 1.0 isoniazid
hadA 732358 c.429G>A synonymous_variant 1.0 isoniazid
hadA 732361 c.432C>T synonymous_variant 1.0 isoniazid
hadA 732364 c.435T>G synonymous_variant 1.0 isoniazid
hadA 732376 p.Asp149Glu missense_variant 1.0 isoniazid
hadA 732378 p.Gly150Glu missense_variant 1.0 isoniazid
hadA 732385 c.456A>T synonymous_variant 1.0 isoniazid
hadA 732391 c.462T>A synonymous_variant 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734484 c.231C>T synonymous_variant 1.0 rifampicin
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734508 c.255C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734553 c.300C>T synonymous_variant 1.0 rifampicin
nusG 734554 c.301_303delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>C synonymous_variant 1.0 rifampicin
nusG 734595 p.Asp114Glu missense_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760145 c.339C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>G synonymous_variant 0.97 rifampicin
rpoB 760256 c.450C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>G synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.93 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>G synonymous_variant 0.97 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 c.757delCinsAT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 760566 p.Ser254Ala missense_variant 0.94 rifampicin
rpoB 760567 c.762delG frameshift_variant 1.0 rifampicin
rpoB 760571 c.765G>C synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760593 c.787_789delGGCinsA frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760634 c.828T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 0.94 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.9 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760973 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761147 c.1341C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>C synonymous_variant 1.0 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Asp missense_variant 1.0 rifampicin
rpoB 761381 c.1575G>C synonymous_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761437 p.Ala544Glu missense_variant 1.0 rifampicin
rpoB 761441 p.Asp545Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761457 p.Pro551Asp missense_variant 1.0 rifampicin
rpoB 761475 p.Arg557Lys missense_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 1.0 rifampicin
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 1.0 rifampicin
rpoB 761747 c.1941G>T synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761802 p.Met666Leu missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>G synonymous_variant 1.0 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762051 c.2245_2247delCATinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 c.2308_2310delATCinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.99 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762170 c.2364C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762173 c.2367G>A synonymous_variant 0.99 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762197 c.2391C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762348 c.2542_2543delTCinsAG synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.97 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.97 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.97 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.97 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 0.97 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.95 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.95 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoB 762537 c.2731_2733delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762560 c.2754A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762563 c.-807G>T upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoC 762851 c.-519C>T upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247_3249delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763172 c.3366G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763253 c.-117G>C upstream_gene_variant 1.0 rifampicin
rpoC 763259 c.-111G>T upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763420 c.51G>C synonymous_variant 1.0 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763434 p.Gln22Arg missense_variant 1.0 rifampicin Uncertain significance
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 1.0 rifampicin
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 1.0 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763534 c.165T>C synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 1.0 rifampicin
rpoC 763621 c.252C>G synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 1.0 rifampicin
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Asp missense_variant 1.0 rifampicin
rpoC 763787 p.Asp140Asn missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763810 p.Glu147Asp missense_variant 1.0 rifampicin
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764048 p.Thr227Val missense_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764126 p.Thr253Ser missense_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764133 p.Ala255Gly missense_variant 1.0 rifampicin
rpoC 764143 c.774G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764147 c.778_780delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ala missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.97 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764279 c.910_912delCAGinsAC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764285 p.Gly306Asn missense_variant 0.95 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.96 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.96 rifampicin
rpoC 764344 c.975C>G synonymous_variant 0.96 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764491 c.1122G>T synonymous_variant 0.98 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.97 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>G synonymous_variant 0.96 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 0.96 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 0.96 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.98 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.94 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.98 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 0.99 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>G synonymous_variant 0.99 rifampicin
rpoC 764809 c.1440C>G synonymous_variant 0.98 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.98 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764912 p.Met515Leu missense_variant 1.0 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764956 c.1587T>C synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765028 c.1659C>G synonymous_variant 1.0 rifampicin
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 1.0 rifampicin
rpoC 765115 c.1746G>C synonymous_variant 1.0 rifampicin
rpoC 765121 c.1752G>T synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765356 p.Met663Leu missense_variant 0.91 rifampicin
rpoC 765361 c.1992C>G synonymous_variant 0.92 rifampicin
rpoC 765371 c.2002C>T synonymous_variant 0.93 rifampicin
rpoC 765379 c.2010G>C synonymous_variant 0.95 rifampicin
rpoC 765397 c.2028G>T synonymous_variant 1.0 rifampicin
rpoC 765405 p.Leu679Gln missense_variant 1.0 rifampicin
rpoC 765408 p.Gly680Asp missense_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765458 p.Ile697Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765590 p.Arg741Asn missense_variant 1.0 rifampicin
rpoC 765718 p.Asp783Glu missense_variant 0.92 rifampicin Uncertain significance
rpoC 765728 c.2359_2361delCAGinsAT frameshift_variant&missense_variant 0.93 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 0.9 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.91 rifampicin
rpoC 765771 p.Thr801Met missense_variant 0.94 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.97 rifampicin
rpoC 765781 p.Asp804Glu missense_variant 0.97 rifampicin
rpoC 765790 c.2421C>G synonymous_variant 0.97 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.97 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.97 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765817 c.2448G>C synonymous_variant 0.98 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 1.0 rifampicin
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 1.0 rifampicin
rpoC 766428 c.3060_3061insACC conservative_inframe_insertion 1.0 rifampicin
rpoC 766432 c.3063T>C synonymous_variant 1.0 rifampicin
rpoC 766434 c.3065_3066delAGinsGCAGC missense_variant&conservative_inframe_insertion 1.0 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766494 p.Gly1042Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 766513 p.Asp1048Glu missense_variant 1.0 rifampicin
rpoC 766517 p.Thr1050Ser missense_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 1.0 rifampicin
rpoC 766539 c.3171_3174delCGGC frameshift_variant 1.0 rifampicin
rpoC 766546 c.3177G>A synonymous_variant 1.0 rifampicin
rpoC 766548 c.3179_3180insACAA frameshift_variant 1.0 rifampicin
rpoC 766568 c.3199_3201delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766573 c.3204T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 1.0 rifampicin
rpoC 766708 c.3339A>G synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.97 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.98 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.98 rifampicin
rpoC 766758 p.Val1130Ala missense_variant 0.98 rifampicin
rpoC 766763 c.3394_3396delATAinsGG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.98 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766841 c.3472_3474delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766951 c.3582G>C synonymous_variant 0.98 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766969 c.3600C>G synonymous_variant 0.98 rifampicin
rpoC 766973 p.Ala1202Ser missense_variant 0.98 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 0.98 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.97 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ser missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767185 c.3816G>C synonymous_variant 1.0 rifampicin
rpoC 767187 p.Gln1273Arg missense_variant 1.0 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775783 c.2698C>T synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775808 c.2673C>G synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775825 c.2656C>T synonymous_variant 0.59 clofazimine
bedaquiline
mmpL5 775826 c.2655G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775832 c.2647_2649delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775875 p.Gly869Ala missense_variant 0.34 clofazimine
bedaquiline
mmpL5 775877 c.2604C>G synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 775892 p.His863Pro missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775895 c.2584_2586delATCinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775901 c.2580G>A synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 775907 c.2572_2574delCTCinsTG frameshift_variant&synonymous_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775910 c.2571G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 0.35 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.92 clofazimine
bedaquiline
mmpL5 775975 p.Leu836Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2481G>C synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776021 c.2458_2460delGTGinsAC frameshift_variant&missense_variant 0.47 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776024 c.2457G>C synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 776029 p.Leu818Met missense_variant 0.53 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776030 c.2451G>T synonymous_variant 0.82 clofazimine
bedaquiline
mmpL5 776051 c.2428_2430delTTGinsAT frameshift_variant&missense_variant 0.82 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776055 p.Val809Ala missense_variant 0.47 clofazimine
bedaquiline
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781679 c.120C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781703 c.144G>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>T synonymous_variant 0.97 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.97 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.97 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.97 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>A synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781760 c.201T>C synonymous_variant 0.98 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.98 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781775 c.216C>T synonymous_variant 0.98 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.98 streptomycin
rpsL 781817 c.258G>C synonymous_variant 0.98 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.98 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 0.98 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781895 c.336G>A synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781913 c.354C>G synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.93 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 0.95 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.95 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.95 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.95 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.95 linezolid
rplC 800574 c.-235_-233delGTCinsACT upstream_gene_variant 0.95 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 0.95 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.95 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.95 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 0.95 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.95 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.96 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.96 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>C upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800726 c.-83G>A upstream_gene_variant 0.96 linezolid
rplC 800729 c.-80G>C upstream_gene_variant 0.92 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.92 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.9 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.89 linezolid
rplC 800780 c.-29C>G upstream_gene_variant 0.88 linezolid
rplC 800856 c.48A>G synonymous_variant 0.7 linezolid
rplC 801180 c.372C>G synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 0.95 linezolid
rplC 801246 c.438C>G synonymous_variant 0.93 linezolid
rplC 801249 c.441T>C synonymous_variant 0.93 linezolid
rplC 801252 c.444G>C synonymous_variant 0.93 linezolid
rplC 801255 c.447C>T synonymous_variant 0.93 linezolid
rplC 801267 c.459A>T synonymous_variant 0.93 linezolid
rplC 801270 c.462T>C synonymous_variant 0.93 linezolid
rplC 801276 c.468G>C synonymous_variant 0.9 linezolid
rplC 801279 c.471G>C synonymous_variant 0.87 linezolid
rplC 801312 c.504G>C synonymous_variant 0.93 linezolid
rplC 801325 c.517_519delGACinsCG frameshift_variant&missense_variant 0.91 linezolid
rplC 801339 c.531T>G synonymous_variant 0.93 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.93 linezolid
rplC 801348 c.540T>G synonymous_variant 0.93 linezolid
rplC 801354 c.546G>A synonymous_variant 0.93 linezolid Not assoc w R - Interim
rplC 801357 c.549T>C synonymous_variant 0.93 linezolid
rplC 801375 p.Asn189Lys missense_variant 0.91 linezolid
fbiC 1303503 c.573G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303525 p.Ser199Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303585 c.655_657delTCGinsAGC synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303646 p.Ala239Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304502 c.1572G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304508 p.Glu526Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304523 c.1593G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304660 p.Tyr577Phe missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304673 c.1743C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304674 p.Gly582Gln missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304709 c.1779C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1943delAGinsTC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304894 p.Gly655Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304899 p.Arg657Lys missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304919 c.1989C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304988 c.2058G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
sigE 1364931 c.519C>G synonymous_variant 0.93 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.93 pyrazinamide
sigE 1364950 c.538_540delGCAinsTC frameshift_variant&missense_variant 0.93 pyrazinamide Uncertain significance
sigE 1364958 c.546G>C synonymous_variant 0.93 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 0.93 pyrazinamide
sigE 1364964 c.552T>G synonymous_variant 0.93 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.93 pyrazinamide
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 0.93 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 0.94 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.95 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.95 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
sigE 1365027 c.615C>T synonymous_variant 1.0 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.93 pyrazinamide
sigE 1365066 c.654G>C synonymous_variant 0.93 pyrazinamide
sigE 1365069 c.657C>G synonymous_variant 0.93 pyrazinamide
sigE 1365078 c.666C>G synonymous_variant 0.92 pyrazinamide
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472288 n.443A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472298 n.453_468delGTCCGGGTTCTCTCGGinsCGTA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472326 n.481T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472583 n.738T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472675 n.830_839delTCCTTCCTTGinsCTTTCCTAA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472869 n.1024G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472870 n.1025T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276_1277delTTinsCTG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473123 n.1278A>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473289 n.1444_1445delTCinsGTCA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474275 n.618T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474287 n.630T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474289 n.633_646delTTTTCCTCTCCGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474674 n.1017A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053delTinsGCAA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474715 n.1060_1061delAA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474928 n.1271C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475345 n.1688T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475346 n.1689C>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475356 n.1699A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475376 n.1719A>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid Uncertain significance
rrl 1475380 n.1723C>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475397 n.1740G>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475399 n.1743_1748delCACTAA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475617 n.1960C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475626 n.1969T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475636 n.1979A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673802 c.-400A>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673808 c.-394A>C upstream_gene_variant 0.9 ethionamide
isoniazid
fabG1 1673810 p.Ser124Cys missense_variant 0.9 ethionamide
isoniazid
inhA 1673816 c.-386G>A upstream_gene_variant 0.91 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673832 c.-370A>G upstream_gene_variant 0.9 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 1.0 ethionamide
isoniazid
inhA 1673901 c.-301A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674502 p.Thr101Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674513 c.312C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674514 p.Ile105Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674518 p.Asn106Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674526 p.Phe109Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674586 p.Ser129Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674609 c.408G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674628 c.427_428delTCinsAG synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674687 c.486G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674712 p.Val171Ile missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674741 c.540C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674742 p.Lys181Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674765 c.564C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674786 c.585G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674831 c.630_631insACCCA frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674834 c.633C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674835 c.635_639delGCGCC frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674847 p.Gln216Arg missense_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 0.9 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.9 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833734 c.193_195delGCCinsTG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833739 c.198C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833770 c.229_231delAACinsCT frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833778 c.237C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833794 p.Glu85Lys missense_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 p.Glu97Asp missense_variant 1.0 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833994 c.453G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834045 c.504G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834375 c.834G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834399 c.858C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834532 p.Val331Ile missense_variant 1.0 pyrazinamide
rpsA 1834541 p.Pro334Ala missense_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834556 p.Ala339Gln missense_variant 1.0 pyrazinamide
rpsA 1834572 p.Ala344Val missense_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834650 p.Thr370Ser missense_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 c.1192_1194delGCCinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
kasA 2517941 c.-174C>G upstream_gene_variant 0.96 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.95 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.93 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.92 isoniazid
kasA 2517993 c.-122G>A upstream_gene_variant 0.92 isoniazid
kasA 2518459 c.345T>G synonymous_variant 0.9 isoniazid
kasA 2518462 c.348A>G synonymous_variant 0.9 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.9 isoniazid
kasA 2518470 p.Ala119Gly missense_variant 0.9 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.9 isoniazid
kasA 2518488 p.Ser125Thr missense_variant 0.91 isoniazid
kasA 2518496 p.Leu128Ala missense_variant 0.91 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.92 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.92 isoniazid
kasA 2518516 c.402C>G synonymous_variant 0.94 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.95 isoniazid
kasA 2518537 c.423C>G synonymous_variant 0.96 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.96 isoniazid
kasA 2518555 c.441C>G synonymous_variant 0.97 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.97 isoniazid
kasA 2518564 c.450C>G synonymous_variant 0.97 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.97 isoniazid
kasA 2518588 c.474T>G synonymous_variant 0.97 isoniazid
kasA 2518597 c.483C>G synonymous_variant 0.97 isoniazid
kasA 2518603 c.489G>T synonymous_variant 0.96 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518612 c.498C>G synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518636 c.522C>T synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Ile missense_variant 1.0 isoniazid
kasA 2518692 p.Ala193Val missense_variant 1.0 isoniazid
kasA 2518702 c.588C>T synonymous_variant 1.0 isoniazid
kasA 2518705 c.591T>C synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.92 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.9 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.92 isoniazid
kasA 2519098 c.984C>T synonymous_variant 0.92 isoniazid
kasA 2519104 c.990T>C synonymous_variant 0.92 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.92 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 0.92 isoniazid
kasA 2519113 p.Gln333His missense_variant 0.92 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.92 isoniazid
kasA 2519137 c.1023T>C synonymous_variant 0.93 isoniazid
kasA 2519143 c.1029G>A synonymous_variant 0.94 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.93 isoniazid
kasA 2519170 c.1056G>A synonymous_variant 0.93 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519203 c.1089C>T synonymous_variant 1.0 isoniazid
kasA 2519212 c.1098C>A synonymous_variant 1.0 isoniazid
folC 2747281 c.318A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747338 p.Thr87Arg missense_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747353 c.246C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783584 c.457_459delGCCinsCG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783587 c.456G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783668 c.375G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783672 p.Arg124Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783713 c.328_330delATGinsCC frameshift_variant&missense_variant 0.95 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783717 p.Leu109Lys missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783727 p.Val106Ile missense_variant 0.95 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783746 c.297G>A synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783896 c.147G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783947 c.96C>A synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783957 p.Tyr29Leu missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 p.Ser27Asn missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783967 c.76T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783968 p.Thr25Ser missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784017 p.Lys9Arg missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784037 c.6T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3065457 c.735A>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065466 c.726G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065481 c.711T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065484 c.708G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065487 c.705T>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065496 c.696G>T synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065502 p.Asp230Glu missense_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 0.87 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065532 c.660A>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065535 c.657C>T synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065538 c.654G>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065541 c.651A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065547 c.645A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065550 c.642G>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065556 c.636G>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065562 c.630T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065576 p.Ala206Ser missense_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067391 c.555G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067400 c.546C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073926 c.546G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073971 c.501C>T synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073980 c.492C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074025 c.445_447delTTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074042 p.Pro144Ala missense_variant 1.0 para-aminosalicylic_acid
ald 3087224 c.405A>G synonymous_variant 1.0 cycloserine
ald 3087227 c.408C>G synonymous_variant 1.0 cycloserine
ald 3087233 c.414T>C synonymous_variant 1.0 cycloserine
ald 3087236 c.417A>G synonymous_variant 1.0 cycloserine
ald 3087239 c.420C>G synonymous_variant 1.0 cycloserine
ald 3087251 c.432T>C synonymous_variant 1.0 cycloserine
ald 3087257 c.438T>C synonymous_variant 1.0 cycloserine
ald 3087272 c.453A>C synonymous_variant 1.0 cycloserine
ald 3087274 p.Thr152Ser missense_variant 1.0 cycloserine
ald 3087278 p.Gln153His missense_variant 1.0 cycloserine
ald 3087281 c.462G>C synonymous_variant 1.0 cycloserine
ald 3087284 c.465C>A synonymous_variant 1.0 cycloserine
ald 3087290 c.471T>G synonymous_variant 1.0 cycloserine
ald 3087314 c.495C>G synonymous_variant 1.0 cycloserine
lpqB 3624356 c.555C>T synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624359 c.552C>T synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624365 c.546T>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624371 c.540T>G synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624376 p.Val179Met missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624382 p.Lys177Gln missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624383 c.528C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624396 p.Ala172Val missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624404 c.507G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624412 p.Asn167Tyr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624452 c.459T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624467 c.444C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Lys missense_variant 0.91 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625129 c.-219C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625147 c.1465_1467delGTCinsCG frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625162 c.-252T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625165 c.-255G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625168 c.-258G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625207 c.-297C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285