TB-Profiler result

Run: ERR926160
Summary

Run ID: ERR926160

Sample name:

Date: 2024-03-25T21:14:29.179604

Number of reads: 7442862

Percentage reads mapped: 48.29

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.94
lineage4.9 Euro-American (H37Rv-like) None 0.82
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5353 c.114T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 5356 c.117G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCT frameshift_variant&synonymous_variant 0.94 levofloxacin Uncertain significance
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5374 c.135C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5386 c.147G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5389 c.150C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5795 p.Asp186Asn missense_variant 0.85 levofloxacin
moxifloxacin
gyrB 5803 c.564A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5806 c.567C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 5812 c.573C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 5821 c.582G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 5848 c.609G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5858 c.619_621delAACinsGG frameshift_variant&missense_variant 0.87 levofloxacin Uncertain significance
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6094 c.855C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6124 c.885C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6181 c.942C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrB 6283 c.1044C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6299 c.1060C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6326 p.Ser363Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6475 c.-827C>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6487 c.1248C>G synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6490 c.-812T>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6511 c.-791A>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6556 c.-746C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6749 p.Ala504Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6781 c.-521C>T upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.98 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6835 c.-467C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6838 c.-464C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6844 c.-458T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6850 c.-452C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6941 c.-361C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6991 c.-311C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 0.99 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7496 c.195C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7556 c.255C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 0.97 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7614 c.313C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7700 c.399G>A synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7703 c.402G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7775 c.474C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8129 c.828T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8270 c.969G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364Leu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8414 c.1113C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8555 c.1254G>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 p.Glu429Asp missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8666 c.1365G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8708 c.1407G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8741 c.1440C>T synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8829 c.1528_1530delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8843 c.1542G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8882 c.1581G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8927 c.1626G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8963 p.Ile554Met missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9266 p.Asp655Glu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9419 c.2118T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 9431 c.2130G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491127 c.345C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491136 c.354C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491138 p.Glu119Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491321 p.Ala180Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491370 c.588C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491379 c.597C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491562 c.780C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491605 c.823C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575833 c.486C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575857 c.510G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.9 ethionamide
Rv0565c 657668 c.-200_-198delACCinsGG upstream_gene_variant 0.97 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.97 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCG upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-262G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731717 c.-213T>C upstream_gene_variant 0.96 isoniazid
hadA 731726 c.-204C>T upstream_gene_variant 0.98 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 1.0 isoniazid
hadA 731738 c.-192G>C upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>G upstream_gene_variant 0.99 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.99 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.99 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.99 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.99 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.88 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.96 isoniazid
hadA 731823 c.-107_-105delCTGinsAC upstream_gene_variant 0.95 isoniazid
nusG 734383 p.Ser44Leu missense_variant 0.88 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.93 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.94 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.97 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.96 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.99 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.99 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.99 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.98 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.96 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.93 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>C synonymous_variant 0.93 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.93 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.93 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.93 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.93 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.94 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.96 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.96 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734922 c.669C>T synonymous_variant 1.0 rifampicin
nusG 734928 c.675A>G synonymous_variant 1.0 rifampicin
nusG 734931 c.678A>G synonymous_variant 1.0 rifampicin
rpoB 760121 c.315T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.98 rifampicin
rpoB 760140 c.334_336delCCCinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>T synonymous_variant 0.99 rifampicin
rpoB 760223 c.417T>C synonymous_variant 0.99 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.99 rifampicin
rpoB 760283 c.477G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.98 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.97 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.97 rifampicin
rpoB 760317 c.511_513delAGCinsTCG synonymous_variant 0.97 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.98 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.98 rifampicin
rpoB 760337 c.531C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760340 c.534G>C synonymous_variant 0.99 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760514 c.708C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760585 p.Asn260Thr missense_variant 1.0 rifampicin
rpoB 760590 p.Val262Ser missense_variant 0.99 rifampicin
rpoB 760607 c.801G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.99 rifampicin
rpoB 760721 c.915C>G synonymous_variant 0.98 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>T synonymous_variant 0.98 rifampicin
rpoB 760730 c.924T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.97 rifampicin
rpoB 760796 c.990A>G synonymous_variant 0.93 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.93 rifampicin
rpoB 760808 c.1002C>G synonymous_variant 0.93 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.93 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.93 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 0.93 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760847 c.1041C>T synonymous_variant 0.98 rifampicin
rpoB 760848 p.Thr348Ser missense_variant 0.98 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.98 rifampicin
rpoB 760865 c.1059C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>T synonymous_variant 1.0 rifampicin
rpoB 760880 c.1074G>C synonymous_variant 0.98 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.98 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.98 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.98 rifampicin Uncertain significance
rpoB 760916 c.1110C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.96 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.93 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.92 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.96 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.94 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.94 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.97 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761303 c.1497G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.97 rifampicin
rpoB 761347 p.Val514Glu missense_variant 0.96 rifampicin
rpoB 761349 p.Asp515Asn missense_variant 0.97 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.97 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.97 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.98 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.98 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.82 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.88 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.99 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.99 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.98 rifampicin
rpoB 761657 c.1851C>A synonymous_variant 0.98 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.98 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.97 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.97 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.98 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 1.0 rifampicin
rpoB 761711 c.1905C>G synonymous_variant 0.97 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 0.97 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 0.97 rifampicin
rpoB 761728 p.Ser641Thr missense_variant 0.93 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761747 c.1941G>C synonymous_variant 0.93 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.97 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.99 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 0.84 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.96 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.95 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.96 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.99 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.99 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.98 rifampicin Uncertain significance
rpoB 762134 c.2328C>T synonymous_variant 0.98 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.98 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.99 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>T synonymous_variant 0.98 rifampicin
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.98 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.97 rifampicin
rpoB 762305 c.2499G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.89 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762320 c.2514C>G synonymous_variant 0.92 rifampicin
rpoB 762329 c.2523G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.95 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.95 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.94 rifampicin
rpoB 762348 c.2542_2543delTCinsAG synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.98 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.97 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 762810 c.3004_3006delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762814 p.Met1003Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762899 c.3093G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.99 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.99 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.98 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763049 c.-321G>A upstream_gene_variant 0.99 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.99 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 0.99 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.98 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.97 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.97 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.96 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.94 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.94 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.93 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.93 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.95 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.98 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 0.98 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 0.96 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.96 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 0.99 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.98 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>T synonymous_variant 0.99 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763747 c.378G>A synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.99 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.99 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.97 rifampicin
rpoC 763825 c.456G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 0.92 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.83 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.97 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.97 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.99 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.99 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.99 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.99 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.99 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.99 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 1.0 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.99 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.99 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.92 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763967 p.Gly200Ser missense_variant 0.99 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.99 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>T synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.97 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.97 rifampicin
rpoC 764056 c.687G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764059 c.690G>T synonymous_variant 0.94 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.94 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.95 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.97 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.97 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.98 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.98 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.97 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.97 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.98 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.98 rifampicin
rpoC 764254 c.885G>C synonymous_variant 0.99 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.99 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.99 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.99 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764296 c.927G>C synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>T synonymous_variant 1.0 rifampicin
rpoC 764353 c.984G>C synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 0.99 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.99 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.99 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.99 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.99 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.97 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.99 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.98 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.99 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 1.0 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCT frameshift_variant&synonymous_variant 0.92 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764920 c.1551G>C synonymous_variant 0.96 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.95 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764962 c.1593G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 0.99 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765016 c.1647C>G synonymous_variant 0.99 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.96 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765338 p.Gln657Lys missense_variant 0.93 rifampicin
rpoC 765357 p.Met663Thr missense_variant 0.96 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.97 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765373 c.2004G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765404 p.Leu679Lys missense_variant 0.99 rifampicin
rpoC 765407 c.2038_2040delGGTinsAC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.99 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.98 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.99 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.99 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765577 c.2208G>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.88 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.91 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.93 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.95 rifampicin
rpoC 765814 c.2445A>C synonymous_variant 0.96 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.96 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.99 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.98 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.94 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.93 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.95 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.97 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.97 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>T synonymous_variant 0.96 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 0.96 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 0.96 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.96 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 0.93 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.93 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.93 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766712 c.3343_3345delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.97 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.97 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.97 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.97 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.97 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.97 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 0.99 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.98 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.98 rifampicin
rpoC 766951 c.3582G>C synonymous_variant 0.98 rifampicin
rpoC 766960 c.3591C>T synonymous_variant 0.98 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766975 c.3606C>A synonymous_variant 0.98 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767163 p.Asn1265Ser missense_variant 0.99 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.99 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>T synonymous_variant 0.94 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.99 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.98 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpsL 781571 c.12C>T synonymous_variant 0.99 streptomycin
rpsL 781592 c.33T>C synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>G synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.99 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>G synonymous_variant 1.0 streptomycin
rpsL 781670 c.111G>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781706 c.147T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.99 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.99 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.99 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.99 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.99 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.98 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.86 streptomycin
rpsL 781769 c.210G>A synonymous_variant 1.0 streptomycin
rpsL 781781 c.222G>T synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>T synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781910 c.351C>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>G synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
rplC 800516 c.-293G>C upstream_gene_variant 0.98 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.97 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.97 linezolid
rplC 800549 c.-260G>T upstream_gene_variant 0.97 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.9 linezolid
rplC 800603 c.-206G>T upstream_gene_variant 0.79 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.91 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.95 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.96 linezolid
rplC 800642 c.-167C>T upstream_gene_variant 0.97 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.97 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.97 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.97 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.98 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.98 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.99 linezolid
rplC 800729 c.-80G>C upstream_gene_variant 0.99 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 0.98 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.97 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.97 linezolid
rplC 800768 c.-41C>A upstream_gene_variant 0.96 linezolid
rplC 801171 c.363A>G synonymous_variant 0.95 linezolid
rplC 801174 c.366T>C synonymous_variant 0.97 linezolid
rplC 801195 c.387G>C synonymous_variant 0.98 linezolid
rplC 801207 c.399C>T synonymous_variant 0.98 linezolid
rplC 801210 c.402T>C synonymous_variant 0.98 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.98 linezolid
rplC 801237 c.429G>C synonymous_variant 0.97 linezolid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303593 c.663G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303959 c.1029C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303968 c.1038G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303977 c.1047C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304667 c.1737G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1305400 p.His824Asn missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305422 p.Ala831Glu missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305456 c.2526C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305459 c.2529G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305462 c.2532G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305474 c.2544T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
sigE 1364742 c.330A>G synonymous_variant 0.98 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.99 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.99 pyrazinamide
sigE 1364767 c.355_357delAGGinsCC frameshift_variant&missense_variant 0.99 pyrazinamide Uncertain significance
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.99 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.99 pyrazinamide
sigE 1364839 c.427_429delTTGinsCT frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.99 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.98 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.97 pyrazinamide
sigE 1364871 c.459C>T synonymous_variant 1.0 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364907 c.495G>C synonymous_variant 0.99 pyrazinamide
sigE 1364919 p.Asp169Glu missense_variant 0.99 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.99 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.99 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 1.0 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 0.99 pyrazinamide
sigE 1365072 c.660G>C synonymous_variant 1.0 pyrazinamide
sigE 1365081 c.669G>A synonymous_variant 1.0 pyrazinamide
atpE 1461149 c.105T>G synonymous_variant 0.92 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.93 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.93 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 0.94 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.95 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.93 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.93 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.93 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.93 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.94 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.93 bedaquiline
atpE 1461227 c.183G>A synonymous_variant 0.92 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 0.92 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.92 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.95 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.95 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472290 n.445C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474008 n.352delA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474016 n.359C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474022 n.365G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474026 n.369C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTCCAAG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474953 n.1296C>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475017 n.1360_1361insA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475202 n.1545G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475233 n.1576C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475242 n.1585G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475271 n.1614A>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475275 n.1618delCinsGG non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475285 n.1628G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475297 n.1640C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475343 n.1686A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475358 n.1701T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475378 n.1721A>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475379 n.1722G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475387 n.1730C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475762 n.2105G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107_2108delAAinsTTTGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
inhA 1674480 c.279T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 0.86 ethionamide
isoniazid
inhA 1674507 c.306G>T synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.88 ethionamide
isoniazid
inhA 1674687 c.486G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674828 p.Glu209Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1674838 p.Ala213Gln missense_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 c.682_684delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 0.89 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 0.93 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.95 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.96 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.96 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.95 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833658 c.117C>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1833664 c.123C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.99 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.99 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.98 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.99 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.99 pyrazinamide
rpsA 1833838 c.297G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.99 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.99 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.99 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.99 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.97 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 0.99 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.99 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.99 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.99 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.98 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.99 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.99 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.98 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834852 c.1311C>T synonymous_variant 0.88 pyrazinamide
tsnR 1853417 c.-189G>C upstream_gene_variant 0.99 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.99 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.99 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.99 linezolid
tsnR 1853441 c.-165C>T upstream_gene_variant 0.97 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.97 linezolid
tsnR 1853453 c.-153G>T upstream_gene_variant 0.97 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.97 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.97 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.98 linezolid
tsnR 1853516 c.-90C>T upstream_gene_variant 0.99 linezolid
tsnR 1853525 c.-81G>C upstream_gene_variant 0.99 linezolid
tsnR 1853528 c.-78G>C upstream_gene_variant 0.99 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 0.99 linezolid
tsnR 1853540 c.-66A>G upstream_gene_variant 0.99 linezolid
tsnR 1853546 c.-60C>G upstream_gene_variant 0.99 linezolid
tsnR 1853552 c.-54C>G upstream_gene_variant 1.0 linezolid
tsnR 1853561 c.-45G>A upstream_gene_variant 1.0 linezolid
ndh 2102053 c.990G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102059 c.984T>C synonymous_variant 0.98 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102065 c.978G>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102068 c.975T>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102071 c.972C>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102077 c.966T>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102086 c.957G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102206 c.837G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102218 c.825C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102227 c.816C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102242 c.801G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 0.99 ethionamide
delamanid
isoniazid
ndh 2102251 c.792C>G synonymous_variant 0.99 ethionamide
delamanid
isoniazid
ndh 2102260 c.783C>T synonymous_variant 0.99 ethionamide
delamanid
isoniazid
ndh 2102469 c.574C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102470 c.573G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102491 c.552A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102494 c.549T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102497 c.546T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102503 c.540C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102509 c.534T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102512 c.531G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102518 c.525T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102527 c.516A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102533 c.508_510delCTAinsTG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102610 c.433T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102614 c.429C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102623 c.420C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102653 c.390T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102668 c.375T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102677 c.366C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102694 p.Val117Ile missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
katG 2155080 c.1032G>C synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517980 c.-135C>G upstream_gene_variant 1.0 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517992 c.-123C>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.99 isoniazid
kasA 2518031 c.-84G>C upstream_gene_variant 0.95 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.81 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.81 isoniazid
kasA 2518156 c.42T>G synonymous_variant 0.93 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.99 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.99 isoniazid
kasA 2518219 c.105T>C synonymous_variant 0.99 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.99 isoniazid
kasA 2518240 c.126C>T synonymous_variant 0.99 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.99 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.99 isoniazid
kasA 2518279 c.165T>C synonymous_variant 0.91 isoniazid
kasA 2518603 c.489G>T synonymous_variant 0.85 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.85 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.88 isoniazid
kasA 2518612 c.498C>G synonymous_variant 0.9 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.94 isoniazid
kasA 2518633 c.519G>C synonymous_variant 0.95 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.96 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.96 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.97 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.98 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.98 isoniazid
kasA 2518687 c.573C>T synonymous_variant 0.99 isoniazid
kasA 2518688 p.Val192Phe missense_variant 0.99 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.99 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.98 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.98 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.98 isoniazid
kasA 2518727 c.613C>T synonymous_variant 0.98 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.97 isoniazid
kasA 2518798 c.684G>T synonymous_variant 0.74 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.99 isoniazid
kasA 2518840 c.726C>A synonymous_variant 0.77 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.76 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.76 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.99 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.99 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.94 isoniazid
kasA 2518882 c.769_*835del stop_lost&conservative_inframe_deletion&splice_region_variant 0.94 isoniazid
kasA 2518882 c.768C>G synonymous_variant 0.88 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.88 isoniazid
kasA 2519044 c.930G>C synonymous_variant 0.94 isoniazid
kasA 2519049 p.Gly312Ala missense_variant 0.94 isoniazid
kasA 2519053 c.939G>C synonymous_variant 0.94 isoniazid
kasA 2519056 c.942G>C synonymous_variant 0.95 isoniazid
kasA 2519059 c.945G>C synonymous_variant 0.95 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.96 isoniazid
kasA 2519068 c.954C>G synonymous_variant 0.95 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.95 isoniazid
kasA 2519077 c.963G>C synonymous_variant 0.95 isoniazid
kasA 2519090 p.Ile326Leu missense_variant 0.95 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.92 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.94 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.93 isoniazid
kasA 2519176 c.1062G>A synonymous_variant 0.93 isoniazid
kasA 2519180 c.1066_1068delGTGinsAC frameshift_variant&missense_variant 0.92 isoniazid
kasA 2519191 c.1077G>C synonymous_variant 0.94 isoniazid
kasA 2519195 c.1081_1083delACGinsGT frameshift_variant&missense_variant 0.94 isoniazid
kasA 2519200 c.1086G>C synonymous_variant 0.94 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726378 c.186T>G synonymous_variant 1.0 isoniazid
ahpC 2726381 c.189C>G synonymous_variant 1.0 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726405 c.213C>G synonymous_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726411 p.Asp73Glu missense_variant 1.0 isoniazid
ahpC 2726414 p.Glu74Asp missense_variant 0.97 isoniazid
ahpC 2726582 c.390G>C synonymous_variant 1.0 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726622 p.Ile144Val missense_variant 1.0 isoniazid
ahpC 2726633 c.441C>G synonymous_variant 1.0 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726648 c.456T>C synonymous_variant 1.0 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782576 c.1467C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 p.Ala295Val missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783176 c.865_867delCAGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2680 2996329 c.225T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996350 c.-389C>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996356 c.-383G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 0.99 capreomycin
Rv2680 2996366 c.262_264delTATinsCC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2680 2996381 p.Ser93Ala missense_variant 1.0 capreomycin
Rv2680 2996386 p.Asp94Glu missense_variant 1.0 capreomycin
Rv2681 2996389 c.-350A>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996401 c.-338T>G upstream_gene_variant 0.97 capreomycin
Rv2752c 3065892 c.300C>T synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>T synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065947 p.Gly82Ala missense_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsGC frameshift_variant&missense_variant 0.93 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065961 c.231G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
thyX 3067646 c.300C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067676 c.270C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067680 p.Cys89Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067699 p.Thr83Ser missense_variant 1.0 para-aminosalicylic_acid
thyA 3073800 c.672G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073819 c.652_653insCC frameshift_variant 1.0 para-aminosalicylic_acid
thyA 3073822 c.648_649delAC frameshift_variant 1.0 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073834 p.Val213Thr missense_variant 1.0 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073854 c.618C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073896 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.550_552delCTCinsTG frameshift_variant&synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.99 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.99 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3624396 p.Ala172Val missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624404 c.507G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624412 p.Asn167Tyr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624452 c.459T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624455 c.456G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624575 c.336T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624581 c.330A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624584 c.327G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624591 p.Thr107Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624603 p.Lys103Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624605 p.Glu102Asp missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624610 p.Ala101Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624614 c.297A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624636 p.His92Arg missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624659 c.252C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624671 c.240C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624675 p.Asn79Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624677 c.234C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624683 c.228G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.225A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624725 c.186G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624752 c.159C>G synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.92 bedaquiline
rifampicin Uncertain significance
lpqB 3625207 c.-297C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625216 c.-306G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625246 c.-336G>T upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625262 p.Tyr451Phe missense_variant 0.97 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625273 c.-363C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.99 bedaquiline
rifampicin
mtrB 3625744 c.870G>A synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625753 p.Ala287Gln missense_variant 0.98 bedaquiline
rifampicin
mtrB 3625762 c.852A>T synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625765 c.-855C>A upstream_gene_variant 0.99 bedaquiline
rifampicin
mtrB 3625774 c.840G>A synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625807 c.807C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625845 p.Ser257Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 0.99 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625882 c.-972G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626669 c.-56T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626705 c.-92G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626792 c.558G>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626825 c.-212T>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626840 c.-227C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626843 c.-230G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626858 c.-245A>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.99 bedaquiline
rifampicin Uncertain significance
mtrB 3626987 c.-374C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627005 c.-392G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627014 c.-401G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627023 c.-410C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.98 bedaquiline
rifampicin
mtrB 3627044 c.-431C>T upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627056 c.-443C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.98 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.97 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.97 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.97 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.99 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.99 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 0.99 rifampicin
rpoA 3877764 c.744C>A synonymous_variant 0.99 rifampicin
rpoA 3877770 c.738A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877794 c.714G>T synonymous_variant 1.0 rifampicin
rpoA 3877884 c.624G>C synonymous_variant 0.88 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.94 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3877926 c.580_582delCTGinsAC frameshift_variant&missense_variant 0.99 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877968 c.540C>G synonymous_variant 1.0 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.94 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.94 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.94 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.97 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.96 rifampicin
rpoA 3878166 c.342C>A synonymous_variant 0.96 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>C synonymous_variant 0.97 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Val missense_variant 0.93 rifampicin
rpoA 3878202 c.306G>C synonymous_variant 0.94 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878241 p.Glu89Asp missense_variant 0.98 rifampicin
rpoA 3878244 p.Glu88Asp missense_variant 0.98 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.98 rifampicin
rpoA 3878250 c.258C>G synonymous_variant 0.98 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.98 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.98 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878665 c.-158A>G upstream_gene_variant 0.78 rifampicin Uncertain significance
rpoA 3878672 c.-166_-165delTAinsCT upstream_gene_variant 0.81 rifampicin
rpoA 3878683 c.-176G>C upstream_gene_variant 0.81 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.85 rifampicin
rpoA 3878701 c.-194C>T upstream_gene_variant 0.85 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.9 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.82 rifampicin
rpoA 3878917 c.-410G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 1.0 rifampicin
rpoA 3878944 c.-437G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878950 c.-443C>G upstream_gene_variant 0.97 rifampicin
rpoA 3878956 c.-449G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 0.97 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 0.97 rifampicin
rpoA 3879040 c.-535_-533delGTGinsAAC upstream_gene_variant 0.97 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.99 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.99 rifampicin
rpoA 3879088 c.-582_-581delCAinsGC upstream_gene_variant 0.99 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879121 c.-615_-614delTTinsAG upstream_gene_variant 0.97 rifampicin
rpoA 3879124 c.-618_-617delTGinsGT upstream_gene_variant 0.97 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.97 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.97 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.98 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.98 rifampicin
clpC1 4038456 p.Val750Glu missense_variant 0.94 pyrazinamide
clpC1 4038461 c.2244G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038474 p.Ser744Thr missense_variant 0.97 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.99 pyrazinamide
clpC1 4038490 p.Ala739Ser missense_variant 0.99 pyrazinamide
clpC1 4038491 c.2214C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.99 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.99 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.99 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038587 c.2118C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038593 c.2112C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038605 c.2100G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038613 p.Asn698His missense_variant 1.0 pyrazinamide
clpC1 4038614 c.2091C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.99 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038677 c.2026_2028delCCGinsGC frameshift_variant&missense_variant 0.96 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 0.98 pyrazinamide
clpC1 4038695 c.2010C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.99 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038881 c.1824C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039007 c.1698G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.99 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039082 c.1623C>T synonymous_variant 0.99 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.99 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.99 pyrazinamide
clpC1 4039100 c.1605C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039119 c.1585_1586delTCinsAG synonymous_variant 0.87 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.97 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039238 c.1467C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039289 c.1416T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039328 c.1377A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039385 c.1320C>T synonymous_variant 0.99 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.99 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.99 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.99 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.99 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.99 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.99 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.99 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 0.99 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039574 c.1129_1131delGCGinsTC frameshift_variant&missense_variant 0.99 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.99 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.99 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.99 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.99 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.99 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 0.99 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040330 c.375C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040417 c.288G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040426 c.279T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.99 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.99 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040549 c.154_156delTTGinsCC frameshift_variant&missense_variant 0.96 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.98 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040681 c.24T>C synonymous_variant 0.99 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.97 pyrazinamide
clpC1 4040696 c.9A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.97 pyrazinamide
glpK 4138558 p.Ala400Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>T synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1153_1155delTCGinsAGC synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138775 c.981C>A synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139561 c.195G>A synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139585 c.171G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.157_159delGCCinsCG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139600 c.156G>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139615 c.141G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139624 c.132C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
ethA 4327686 c.-213C>G upstream_gene_variant 1.0 ethionamide
ethA 4327692 c.-219G>A upstream_gene_variant 1.0 ethionamide
ethA 4327695 c.-222A>G upstream_gene_variant 1.0 ethionamide
ethA 4327704 c.-231C>T upstream_gene_variant 1.0 ethionamide
ethA 4327713 c.-240A>C upstream_gene_variant 1.0 ethionamide
ethA 4327720 c.-247T>G upstream_gene_variant 1.0 ethionamide
ethA 4327746 c.-273T>C upstream_gene_variant 0.93 ethionamide
ethA 4327749 c.-276G>C upstream_gene_variant 0.91 ethionamide